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Sentenac, Flore. "Learning and Algorithms for Online Matching." Electronic Thesis or Diss., Institut polytechnique de Paris, 2023. http://www.theses.fr/2023IPPAG005.
Анотація:
Cette thèse se concentre principalement sur les problèmes d'appariement en ligne, où des ensembles de ressources sont alloués séquentiellement à des flux de demandes. Nous les traitons à la fois du point de vue de l'apprentissage en ligne et de l'analyse compétitive, toujours lorsqueEn ce qui concerne l'apprentissage en ligne, nous étudions comment la structure spécifique de l'appariement influence l'apprentissage dans la première partie, puis comment les effets de report dans le système affectent ses performances.En ce qui concerne l'analyse compétitive, nous étudions le problème de l'appariement en ligne dans des classes spécifiques de graphes aléatoires, dans un effort pour s'éloigner de l'analyse du pire cas.Enfin, nous explorons la manière dont l'apprentissage peut être exploité dans le problème d'ordonnancement des machinesThis thesis focuses mainly on online matching problems, where sets of resources are sequentially allocated to demand streams. We treat them both from an online learning and a competitive analysis perspective, always in the case when the input is stochastic.On the online learning side, we study how the specific matching structure influences learning in the first part, then how carry-over effects in the system affect its performance.On the competitive analysis side, we study the online matching problem in specific classes of random graphs, in an effort to move away from worst-case analysis.Finally, we explore how learning can be leveraged in the scheduling problem
2
Thiry, Arnauld. "Assessment of plant hormone quantification as a new physiological trait for crop breeding using a new classification method for crop performance under drought." Thesis, Lancaster University, 2017. http://eprints.lancs.ac.uk/90099/.
Анотація:
The need to accelerate the selection of crop genotypes that are both resistant to and productive under abiotic stress is enhanced by global warming and the increase in demand for food by a growing world population. In this thesis, a new method is proposed for evaluation of wheat genotypes in terms of their resilience to stress and their production capacity. The method quantifies the components of the new index related with yield and yield components under abiotic stress. The index method, based on a scoring scale, offers a simple and easy visualization and identification of resilient, productive genotypes, according to their yield and yield components. This new selection method could help breeders and researchers by defining clear and strong criteria to identify genotypes with high resilience and high productivity and to reveal where genotypes express their susceptibility to a stress environment, providing a quantitative classification of contrasts in terms of yield and yield components. This index method has allowed 1) the identification of contrasting genotypes from a small population (CIMCOG-ROOT, 10 genotypes), and 2) the quantification of their contrasts, in terms of yield and yield components (grain number per spike), both constituting a key opportunity to test whether a stress hormone and/or hormone balance (ABA, ethylene and/or ABA/ethylene) could be used as a physiological trait for breeding for abiotic stress resilience. Due to the complexity of spatial and temporal variation of hormone accumulation (ABA and ethylene) and their different effects in plant development in response to stress environments, it is necessary to investigate how factors other than environment can influence the production of hormones. The factors considered in this work were: day time, water management (irrigation), tissue specificity (leaf and spike) and wheat phenological development (phenological stages). The present study of hormone (ABA and ethylene) quantification in wheat has shown that the genotypic variation in hormone signalling cannot be identified at every developmental stage of the plant. In fact, only two stages were identified for differences in ethylene emission (late- booting and heading), and two for ABA accumulation (late-booting and half-emergence), both on leaf tissue. However, the ratio ABA/ethylene (ABA/ETH) emerges as a better method to study genotypic variation in response to stress environments, in terms of hormone accumulation. In fact, both tissues, leaf and spike at all stages during the pre-anthesis stage (from booting to heading), have shown significant genotypic variation in terms of ABA/ETH balance. The resilience index of grain number per spike and this study of hormone (ABA and ethylene) quantification under drought stress (on leaf and spike), have shown that at late-booting stage, a lower leaf hormone ratio ABA/ETH and higher leaf ethylene emission is associated with a higher resilience of spike fertility (grain per spike resilience). However, under controlled conditions, a possible optimum threshold is observed in terms of leaf hormone ratio ABA/ETH. These results have been obtained with statistical significance in eight genotypes under field conditions and four genotypes under controlled environments. It is suggested in this work that a possible method for early selection of genotypes for high spike fertility resilience under drought stress could be developed by quantifying hormone signalling (leaf ethylene and the leaf ratio ABA/ETH at late-booting stage). However, some improvements in the process of hormone quantification need to be made before recommending this method to breeders.
3
Capewell, Adam Daniel. "Novel grading of silicon germanium for high quality virtual substrates." Thesis, University of Warwick, 2002. http://wrap.warwick.ac.uk/90799/.
Анотація:
The growth of SiGe virtual substrates, by solid-source molecular beam epitaxy (SS-MBE), using a new germanium grading technique has been studied. It is proposed that the grading of germanium using a series of linearly graded/uniform layers (terrace grading) prevents the dislocation pile-ups, associated with strain relief, from penetrating the entire epilayer. Since the dislocation pile-ups cause threading dislocations to become trapped and increase the roughness of the surface, the control of these pile-ups reduces both the threading dislocation density and the RMS surface roughness. Si0.50Ge0.50 virtual substrates of 2 µm thickness using the terrace grading technique have been studied and compared to conventional linear graded and step graded virtual substrates of the same thickness. Substantial reductions in both the RMS roughness and threading dislocation densities are found in the terrace graded structure, compared with the conventional techniques. Electrical properties have been measured in layers grown on virtual substrates using the terrace grading and show promisingly high hole mobilities. The mechanism by which the terrace graded virtual substrates relax has been examined in order to optimise the growth conditions. It is found that the lowest layers of the virtual substrates do not relax until sufficient strain energy is accumulated by the growth of the following layers, leading to dislocation pile-ups that extend through several layers. The use of in-situ anneals has been shown to greatly improve the relaxation of the lower layers, with a corresponding decrease in the size of the pile-ups, and consequently lower threading dislocation densities have been found.
4
Zanetti, Davide. "Comunicazioni sicure su canali eterogenei: un'analisi sistematica di SSL da Java a Jolie." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/9099/.
Анотація:
All’interno di questa tesi è stata affrontata la tematica della realizzazione di comuni- cazioni sicure, in modo da ottenere l'indipendenza di queste ultime dal canale utilizzato, con l'ausilio di strumenti in grado di fornire supporto per la creazione di applicativi orientati allo scambio di dati e messaggi, quali i linguaggi di programmazione Java e Jolie, il quale è basato sul precedente.
Sono state inizialmente analizzate le principali caratteristiche e le problematiche più importanti che è necessario dover risolvere in modo da poter arrivare al risultato desiderato.
Successivamente, è stato dato un ampio sguardo ad una delle scienze più applicate per risolvere i problemi tipici che affliggono questo tipo di comunicazioni, la crittografia. Sono stati elencati gli strumenti messi a disposizione ed il loro funzionamento.
La crittografia viene poi applicata al protocollo SSL, il quale rappresenta la soluzione maggiormente diffusa, sia sul Web che in altri ambiti, per proteggere le informazioni personali che transitano tra gli end-point di una comunicazione. Sono state elencate le principali caratteristiche, alcuni cenni riguardanti la nascita e lo sviluppo ed è stato descritto il funzionamento di questo protocollo, soprattutto per quanto riguarda la sua fase preliminare, che è una delle parti che lo caratterizzano maggiormente.
In seguito, è stata analizzata la soluzione fornita all’interno delle librerie del linguaggio Java per realizzare comunicazioni indipendenti dal mezzo di comunicazione che soddisfino le politiche dettate dal protocollo SSL. Questa soluzione è rappresentata dalla classe SSLEngine, che è quindi stata esaminata, a partire dal ciclo di vita e dall'inizializzazione, fino ad arrivare all'interazione all'interno di un applicazione.
Quanto esplorato in precedenza viene poi applicato a Jolie, un linguaggio di programmazione basato sulle comunicazioni e sviluppato in Java, all'interno dell'Università di Bologna. Dopo uno sguardo generale alle sue caratteristiche è stata approfondita la gestione dei protocolli, e di conseguenza, l'introduzione di SSL all'interno di essi, realizzata tramite la classe SSLProtocol. Questa classe contiene ed implementa i concetti analizzati nel capitolo riguardante Java, adattandoli all'architettura ed alla progettazione pensata appositamente per Jolie; è stata quindi effettuata un'analisi del codice e della gestione della classe SSLEngine per realizzare comunicazioni sicure. Infine, per verificare l’effettivo funzionamento, sono stati creati due semplici casi d’uso per poter sfruttare i vantaggi offerti da Jolie, il quale è particolarmente indicato per la creazione di applicazioni orientate ai servizi.
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Tian, Na. "Novel optimisation methods for numerical inverse problems." Thesis, University of Greenwich, 2011. http://gala.gre.ac.uk/9099/.
Анотація:
Inverse problems involve the determination of one or more unknown quantities usually appearing in the mathematical formulation of a physical problem. These unknown quantities may be boundary heat flux, various source terms, thermal and material properties, boundary shape and size. Solving inverse problems requires additional information through in-situ data measurements of the field variables of the physical problems. These problems are also ill-posed because the solution itself is sensitive to random errors in the measured input data. Regularisation techniques are usually used in order to deal with the instability of the solution. In the past decades, many methods based on the nonlinear least squares model, both deterministic (CGM) and stochastic (GA, PSO), have been investigated for numerical inverse problems. The goal of this thesis is to examine and explore new techniques for numerical inverse problems. The background theory of population-based heuristic algorithm known as quantum-behaved particle swarm optimisation (QPSO) is re-visited and examined. To enhance the global search ability of QPSO for complex multi-modal problems, several modifications to QPSO are proposed. These include perturbation operation, Gaussian mutation and ring topology model. Several parameter selection methods for these algorithms are proposed. Benchmark functions were used to test the performance of the modified algorithms. To address the high computational cost of complex engineering optimisation problems, two parallel models of the QPSO (master-slave, static subpopulation) were developed for different distributed systems. A hybrid method, which makes use of deterministic (CGM) and stochastic (QPSO) methods, is proposed to improve the estimated solution and the performance of the algorithms for solving the inverse problems. Finally, the proposed methods are used to solve typical problems as appeared in many research papers. The numerical results demonstrate the feasibility and efficiency of QPSO and the global search ability and stability of the modified versions of QPSO. Two novel methods of providing initial guess to CGM with approximated data from QPSO are also proposed for use in the hybrid method and were applied to estimate heat fluxes and boundary shapes. The simultaneous estimation of temperature dependent thermal conductivity and heat capacity was addressed by using QPSO with Gaussian mutation. This combination provides a stable algorithm even with noisy measurements. Comparison of the performance between different methods for solving inverse problems is also presented in this thesis.
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Abánades, Lázaro Isabel. "The effect of surface functionalisation on cancer cells internalisation and selective cytotoxicity of zirconium metal organic frameworks." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/9099/.
Анотація:
A considerable amount of effort has been directed to develop porous materials as drug delivery systems (DDSs) – one of the most promising emerging applications in healthcare, as most anticancer therapeutics have toxic dose dependence due to a lack of tumour selectivity – as their hierarchical porosity can be used to store and release challenging drugs. Among them, Metal-Organic Frameworks (MOFs) – emerging hybrid, highly porous crystalline structures – offer several advantages compared to other available DDS, as they combine desirable features from both organic (biocompatibility, e.g. porous polymers) and inorganic (high loadings, e.g. mesoporous silica) porous materials. MOFs are highly amenable to functionalisation, meaning fine control over their physical properties can be achieved, and thus they have experienced tremendous development during the past decade in many applications. Despite surface engineering being advantageous for diverse fields – in biomedicine, it can both improve stability and dispersion, and provide the possibility of targeted carriers, decreasing the immune system recognition – surface functionalization of MOFs is underdeveloped. The multiple synthetic steps – synthesis, drug loading and surface modification – and the lack of orthogonality between them hinder their industrial manufacturing as DDSs. This thesis focuses on the development of surface functionalisation protocols of Zirconium MOFs, particularly UiO-66, a Zr-terephthalate MOF, the study of their cell internalisation fate and routes and the correlation with their therapeutic activity. During Chapter 1, an introduction to the use of DDSs in anticancer therapy, followed by examples of the most relevant MOFs from a coordination chemistry point of view, is given, in which zirconium MOFs and their synthesis are highlighted. Particular focus is given to the coordination modulation process, in which monodentate modulators are introduced to the MOFs synthesis to compete with the multidentate linkers during nucleation, enhancing properties such as porosity through the induction of defects. Then, the most relevant examples of surface functionalization of Zr MOFs for drug delivery are discussed with respect to the effects on properties such as colloidal dispersion in aqueous solvents, physiological stability, and drug release kinetics. In Chapter 2 different functionalised modulators (i.e p-functionalised benzoic acids, folic acid or biotin) are introduced to UiO-66 synthesis to obtain surface-functionalised UiO-66 with the appropriate size for drug delivery by one-pot synthesis. Full characterisation of the materials shows them to be remarkably porous due to the defects formed when modulators attach to available zirconium positions in the pores and on the surfaces of the MOFs. Furthermore, the use of a carboxylate-containing anticancer metabolic target (dichloroacetic acid, DCA) as a modulator of UiO-66 synthesis is explored, and co-modulated samples, in which both DCA and functionalised modulators are introduced to UiO-66 synthesis, are synthesised and fully characterised, resulting in drug-containing (ca. 20% w/w) surface-functionalised MOFs by one pot syntheses. Importantly, DCA modulation induces a high number of defects, and consequently highly charged nanoparticles which are colloidally stable in aqueous solvents. Particle size control in the DCA modulated synthesis of the UiO family of isoreticular MOFs – including UiO-66 and its bromo, amino and nitro derivatives, and extended structures Zr-Naphthalenedicarboxylate (NDC) and Zr-Biphenyldicarboxylate (BPDC) – is achieved, obtaining ca. 100 nm particles of UiO-66 derivatives and microcrystals of Zr-NDC and Zr-BPDC when ZrCl4 is the metal precursor, and mesoporous < 20 nm UiO-66 derivatives and ca. 200 nm Zr-NDC and Zr-BPDC when ZrOCl2 is used as the metal precursor. The high porosity of the DCA modulated samples, due to DCA attachment to the inner and outer surface at defect sites, allows the loading of a second drug, the well-known anticancer drug 5-fluorouracil (5-FU), into the pores of the isoreticular MOFs to create dual DDSs. Different postsynthetic modes of surface coating, based in both coordination and covalent chemistry, are studied during Chapter 3. The functionalities of the p-functionalised benzoic acid modulators, introduced to UiO-66 structure during Chapter 2, are used to covalently attach short-chain alkanes and long-chain polymers to UiO-66 surface through copper-catalysed azide-alkyne cycloaddition. Exhaustive characterisation confirms that the attachment occurs through covalent chemistry and not through surface adhesion or electrostatic forces. Folic acid and biotin, which are introduced to UiO-66 surface as synthetic modulators during Chapter 2, are also introduced to UiO-66 surface postsynthetically. Colloidal dispersion and stability towards phosphates are investigated and compared to bare MOFs, in order to gain insights into the effect of both surface chemistry and mode of attachment on physical properties. A comprehensive overview of in vitro studies of cellular internalisation of zirconium MOFs is given in Chapter 4, focussing on the relevance of the endocytosis internalisation routes, which are strictly correlated with therapeutic efficacy. The postsynthetic surface functionalisation protocols investigated in Chapter 3 are applied to analogous calcein-loaded UiO-66 samples. Calcein is a fluorescent molecule not able to efficiently cross the cell membrane by itself, and hence serves as an in ideal probe of MOFs cellular internalisation. Its release from bare and poly(ethylene glycol) coated UiO-66 into phosphate buffered saline at pH 7.4 and 5.5, in order to simulate extracellular and intracellular conditions, is found to be pH responsive (more pronounced at 5.5) for all MOFs, but an ideal decrease in calcein release at pH 7.4 occurs only for PEGylated MOFs. Internalisation of calcein-loaded MOFs by HeLa cervical cancer cells is studied by fluorescence assisted cell sorting, highlighting the effects of surface chemistry on endocytosis efficiencies and internalisation mechanisms. A discussion of in vitro studies into anticancer drug delivery from Zr MOFs is provided in Chapter 5, alongside a summary of the therapeutic effects of DCA and approaches to enhance its anticancer efficacy. Experimental assessment of the in vitro anticancer performance towards MCF-7 breast cancer cells of the DCA-containing MOFs of the UiO family of different sizes (ca. 100 nm and <20 nm), synthesised by coordination modulation during Chapter 2, is given. The effect of dual-drug containing MOFs (DCA and 5-FU) is also examined, to investigate the possible synergic effect of the drug combination. Then, the cytoxicity of bare and surface functionalised, DCA-loaded and empty UiO-66 MOFs is studied at first upon incubation with HeLa cells, for which the cellular routes of internalisation were elucidated in Chapter 4. The most promising MOFs are then tested for selective anticancer activity against a series of cancerous and healthy cells lines, and their macrophage uptake and ROS production is also analysed, to determine the effect of surface functionalization. The selective anticancer cytotoxicity of folate-coated MOFs is attributed to a combination of cancer cell targeting and optimal cell internalisation routes. To summarise, the one-pot synthesis of drug-loaded, surface functionalised UiO-66 has been successfully performed, resulting in porous, crystalline MOFs with the appropriate size for drug delivery. The use of a carboxylate-containing anticancer metabolic target as a modulator has been explored for the UiO family of isoreticular MOFs, resulting in well-dispersed nanoMOFs with enhanced anticancer activity, into which a second drug can be loaded, enabling the creation of dual DDSs.A series of postsynthetic surface modifications are performed, enabling the study of the MOF’s properties (colloidal dispersion, physiological stability and biocompatibility) with respect to their surface chemistry and coating mode, but more importantly providing valuable insights into correlations between surface chemistry, routes of cellular internalisation and therapeutic effect.
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Costa, Nanci Aparecida [UNESP]. "O uso da mídia e a presença dos gêneros textuais no processo ensino-aprendizagem: uma análise do material didático - cadernos do aluno e do professor - de língua portuguesa do estado de São Paulo." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/90099.
Анотація:
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costa_na_me_rcla.pdf: 741331 bytes, checksum: f7afbe1333b565fea5b4dd5d687dda7d (MD5)O objetivo desta pesquisa de mestrado é estudar a questão do uso das mídias e sua inserção no processo de ensino-aprendizagem de Língua Portuguesa, com o intuito de, no primeiro momento, expor os princípios epistemológicos e históricos que dão suporte teórico para tal temática. A partir desta base teórica, estudar como ocorre a presença destes elementos no material em circulação na rede pública de ensino do Estado de São Paulo. Tecendo, desta forma, discussões sobre a influência dos meios de comunicação na educação e na cultura dos alunos. Finalmente, apresentar qualitativamente a presença do uso das mídias nas apostilas de Língua Portuguesa em circulação no ensino público do Estado de São Paulo, discorrendo, a partir de elementos retirados do próprio material trabalhado em sala de aula, a presença dos gêneros textuais no processo de ensino-aprendizagem, utilizando como base a mídia. Assim, mostrando, a distribuição dos gêneros (textuais e midiáticos) em cada uma das quatro apostilas estudadas pelos alunos e utilizadas pelos professores na série final de sua formação no Ensino Médio
The main goal of this research is to study the issue of media utilization and its insertion on the process of learning-teaching of the Portuguese Language to, primarily, expose the epistemological e historical principles that give theoretical support to that theme. From this theoretical basis, to study how the presence of these elements occur at the circulating material on the public teaching of the State of São Paulo. Bringing, thus, discussions about the influence of the communicational means on education e student culture. Finally, to present qualitatively the presence of media utilization on books of Portuguese Language in circulation at the public teaching of the State of São Paulo, bringing, from the elements taken from the material used in class, the presence of textual genres on the teaching-learning process, using as basis the media. This way, showing, the distribution of genres (textual and mediatic) on each of the four books studied by the students and used by the teachers on the final grade of their formation in High School
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Quintanilha, Edson de Castro [UNESP]. "Representações de estudantes do curso de Pedagogia e de professores da rede pública sobre alunos dos anos iniciais." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/90199.
Анотація:
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Este trabalho, ligado à linha de pesquisa “Políticas Públicas, Organização Escolar e Formação de Professores”, teve por objetivo investigar e comparar as representações sociais de estudantes do Curso de Pedagogia da FCT/UNESP e dos professores formados em Cursos de Pedagogia, sobre os alunos dos anos iniciais do Ensino Fundamental da rede municipal de ensino, analisando sua percepção sobre a interferência dessas representações no desenvolvimento do trabalho docente. Para atingir esse objetivo, procuramos responder às perguntas: Que representações sociais os estudantes do Curso de Pedagogia e os professores possuem do aluno dos anos iniciais da escola pública com os quais trabalham ou poderão vir a trabalhar? Estas representações apresentam diferenças após o início da prática docente? Elas podem interferir no desenvolvimento do trabalho docente? Apoiamo-nos, para o desenvolvimento desse trabalho, na teoria das representações sociais de Serge Moscovici. A partir do nosso referencial teórico coletamos os dados necessários, junto aos participantes da pesquisa, por meio de questionário contendo solicitação de evocações sobre “aluno ideal” e “aluno da escola pública” e questões objetivas e subjetivas, permitindo uma triangulação para confirmação das representações pesquisadas. A análise dos dados coletados possibilitou-nos identificar as representações sociais de estudantes do Curso de Pedagogia e dos professores sobre os alunos das séries iniciais da rede pública municipal e refletir sobre os aspectos cognitivos, comportamentais/afetivos e socioculturais nelas contidos. Em seguida analisamos as expectativas docentes nascidas das representações e sua possível influência no sucesso escolar do aluno, valendo-nos da teoria da profecia autorrealizadora...
The present paper is connected to the research line entitled “Public Policies, Scholar Organization and Teachers’ Formation”. The main of this study is to investigate and compare social representations of Pedagogy students’ from FCT/UNESP and teachers’ graduated at Pedagogy about elementary school students from municipal schools. Besides, it aims to analyze how their perception interferes into their practice. In order to reach such objectives we intended to ask the following questions: What social representations Pedagogy students and teachers have about elementary school students from municipal schools with whom they will work? Are such representations different after they start to work as teachers? Can they interfere into teachers’ work? The theoretical base of this paper is Social Representations Theory by Serge Moscovici. The data were collected through questionnaire with objective and subjective questions related to the “ideal student” and the “student from public school”, which provides us to investigate the researched representations. Through data analysis it was possible to identify social representations of Pedagogy students’ and teachers’ about elementary school students from municipal schools. Thus, it was also possible to think about cognitive, behavior/affective and sociocultural aspects inserted into such representations. After that, we analyzed teachers’ expectations brought from their representation and the its possible influence in students’ scholar success, according to self-performing theory ... (Complete abstract click electronic access below)
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Abrantes, Aline Reck Padilha [UNESP]. "Instituição ou instituído?: análise de uma prática escolar de inclusão." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/90299.
Анотація:
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A experiência profissional e os impasses enfrentados no cotidiano de trabalho atual, quando se trata de crianças com algum diagnóstico a serem incluídas na escola regular, instigaramnos a realizar o presente estudo. Partindo do princípio de que a inclusão implica no trabalho de toda instituição escolar é que buscamos na Pedagogia Institucional sustentação para nossa pesquisa. A Pedagogia Institucional, corpo de conhecimentos teóricos que, articulado a prática pedagógica, transforma a classe num laboratório de trabalho constante vem a ser a perspectiva da leitura da prática da Escola de Educação Infantil e Ensino Fundamental Centro Integrado de Desenvolvimento - CID. Os sujeitos foram todos os profissionais e professores desta escola, os alunos do último ano da educação infantil, alunos da primeira série e alunos da última série do ensino fundamental, os pais e uma profissional da Escola Nossa Senhora do Bom Conselho, escola que recebe alunos egressos do CID. Os dados coletados constituíram os seguintes focos de análise: 1. A escola como promotora da unidade. 2. A escola como promotora da autonomia. 3. A troca com os pais. 4. A escola como promotora do diálogo com a sociedade. 5. O trabalho em grupo. 6. A escuta como exercício da ética. 7. A equipe interdisciplinar como suporte. 8. A prática da avaliação. Após analise e discussão reflexiva, consideramos que o cerne da inclusão é a prática instituída no cotidiano da escola e, pensamos que a relevância desta pesquisa está na possibilidade de contribuir com aqueles setores que pretendem instituir a inclusão.
Professional experience and difficulties faced in the routine of current work, concerning children with some kind of diagnostic to be included in the regular school, encouraged us to accomplish the present work. Our work is supported by Institutional Pedagogy for we think that inclusion is the work of the whole school institution. Institutional Pedagogy, theoretical knowledge which when related to pedagogical practice turns the classroom into a laboratory of constant work, is the perspective from what practiced is understood at the Elementary and Middle school CID (Centro Integrado de Desenvolvimento). The subjects were all professionals and teachers from this school, students from the last grade of elementary school and from the first and last grade of middle school, parents and one professional from Bom Conselho school, which admits students from CIC. The collected data were related to the following focus of analysis: 1. The school as unity provider; 2. The school as autonomy provider; 3. Connections between parents and school; 4. The school as dialogue provider in the society; 5. The group work; 6. Hearing as ethics exercise; 7. The interdisciplinary team as support and 8. Evaluation practice. After the analysis and discussion, we have considered the practice instituted in the school routine the key for the inclusion. We think that the relevance of this study is in the possibility of contributing to those sectors which intend to institute the inclusion.
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Pinheiro, Cláudia Ramos [UNESP]. "Avaliação da infiltração bacteriana corono-apical de canais radiculares obturados com diferentes tipos de cimentos endodônticos." Universidade Estadual Paulista (UNESP), 2008. http://hdl.handle.net/11449/90399.
Анотація:
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pinheiro_cr_me_arafo.pdf: 1052559 bytes, checksum: 2a41a237f5d01f6a98076552b4ca2ebd (MD5)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Avaliamos a infiltração coroa-ápice da bactéria Enterococcus faecalis em incisivos centrais bovinos instrumentados e obturados com os cimentos endodônticos AH Plus, Endofill, Epiphany, Acroseal e o cimento experimental à base do Polímero da mamona (Polifil). Foi confeccionado um dispositivo a ser adaptado na porção inferior de tubos de centrífuga, Eppendorf. As raízes, previamente obturadas, foram inseridas nesse dispositivo até que 5mm se projetasse para fora do tubo plástico. A junção entre o tubo e a raiz foi selada com araldite, assim como a porção da raiz, externa ao recipiente, excluindo-se 1 mm ao redor do forame apical. O dispositivo Eppendorf e raiz obturada foram fixados em frasco tipo penicilina, contendo caldo .Brain heart infusion.. Com auxílio de uma pipeta, 1mL da bactéria foi transferido ao caldo B.H.I. e 400 µL de uma cultura recente foram transferidos para a porção superior do tubo. Durante 64 dias, a infiltração bacteriana era detectada através da turvação do caldo. Os resultados foram submetidos à análise estatística. Foi utilizado o método não-paramétrico de Kaplan-Meier e o teste de Kruskal-Wallis, complementado por comparações múltiplas pelo teste de Dunn. Adotou-se o nível de significância de 5%. Os cimentos AH Plus e Endofill apresentaram resistência à infiltração bacteriana significativamente menor do que o Polifil, mas estatisticamente equivalentes entre si. Os cimentos Epiphany e Acroseal deram resultados intermediários e equivalentes, mas sem diferença estatisticamente significante em relação aos outros cimentos.
This study compared some of the endodontic sealers sealing ability (AH Plus, Epiphany, Acroseal, Endofill and Polifil (a castor oil-based experimental sealer) using the active lateral condensation technique, through a bacterial test, during 64 days. One hundred bovine incisors were selected and divided into five experimental groups and two control groups (negative and positive ones). The teeth were cleaned and shaped by the step-back technique, then, they were filled with the endodontic sealers and stored in (100%) wet environment. The roots were impermeabilized with araldite glue, adapted into an eppendorf microtube and sterilized by ethylen oxide gas. The root/ eppendorf microtube was added to penicillin flasks containing 6mL of BHI broth kept at 37º C for 4 days to confirm sterilization. After this period, 400µL of Enterococcus faecalis ATCC 29212 were inserted at the upper portion of the eppendorf microtube. Daily leakage was evaluated through the broth turbidy. The results were submitted to the statistical analysis (Kaplan-Meier method as well as Kruskal-Wallis´ and Dunn´s tests). AH Plus and Endofill sealers were statistically equivalent concerning the sealing property, showing less resistance to the bacterial leakage than Polifil, while Acroseal and Epiphany had similar and intermediate behavior, but without numerical significance when compared to the other sealers.
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Giachini, Camillo Ferrarezi [UNESP]. "Desempenho operacional de uma colhedora de cana-de-açucar ( Saccarum spp.) em função dos turnos de trabalho." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/90499.
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giachini_cf_me_botfca.pdf: 1758286 bytes, checksum: 3db1d4c51bcf405b71434d3425afb037 (MD5)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Universidade Estadual Paulista (UNESP)
A agricultura nos últimos anos vem sofrendo pressões para a modificação de suas técnicas visando o aumento da produtividade, redução dos custos de de produção e a preocupação com o ambiente. Em busca de atingir todos estes fatores, a cultura da cana-de-acucar foi em busca da modernização que ocorreram principlamente no campo.Um gande avanço tecnologico para a producção da cana-de-acúcar foi a substitição do sistema de colheita manual para o sistema mecanizado. A colheita mecanizada passa a suprir a mão de obra utilizada no corte que estava se tornando escassa, além de possibilitar um rendimento na colheita e uma menor agressão ao ambiente uma vez que a queima do canavial deixou de ser utilizada. Por estes fatore o presente trabalho teve por objetivo avaliar o desempenho operacional de uma colhedora de cana-de-açúcar sem queima prévia do canavial durante os três turnos de trabalho da mesma. O ensaio foi realizado na Usina Santa Cândida, pertencente ao Grupo Tonon Biotecnologia,localizada no municipio de Bocaina ,Região Centro Oeste do Estado de São Paulo. O canavial avaliado foi caracterizado...
Agriculture in recent years has been facing pressure to change their techniques in order to increase productivity, reduce production costs and concern for the environment. In seeking to achieve all these factors, the culture of sugar cane was looking for upgrades that occurred mainly in the field. A major technological breakthrough for the mechanized system. Mechanized harvesting is to supply the labor used in the cut that was becoming scarce, and enables at yields at harvest and less aggression to the environment since the burning of sugarcane is no longer used. For these reasons the present study was to evaluate the operating performance of a harvester for cane sugar without previous burning of sugarcane during the three work shifts the same. The test was conducted at Santa Candida. Plant belonging to the group Tonon Bioenergy, located in the municipality of Bocaina, Midwest Region of São Paulo. The sugarcane was assessed... (Complete abstract click electronic access below)
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Rodrigues, João Batista Tolentino [UNESP]. "Variabilidade espacial e correlações entre atributos de solo e produtividade na agricultura de precisão." Universidade Estadual Paulista (UNESP), 2002. http://hdl.handle.net/11449/90599.
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rodrigues_jbt_me_botfca.pdf: 3900979 bytes, checksum: d33a7d85ab838673b26e9b839cca2375 (MD5)A análise de mapas de produtividade, no contexto da agricultura de precisão, é um dos recursos utilizados na tentativa de compreender e manejar a variabilidade espacial da produtividade e da qualidade das culturas. Mapas de produtividade de milho e de soja gerados por um sistema comercial de monitoramento de colheita para as safras de 1998, 1999 e 2000 foram estudados e submetidos a um processo de classificação através da técnica de análise de agrupamento para o conjunto de dados dos três anos reunidos em uma imagem composta. Objetivou-se, a partir dos agrupamentos obtidos, associar algumas tendências de variação no comportamento da produtividade que pudessem caracterizar essas regiões com comportamentos diferenciados dentro da área. Com o auxílio de um levantamento de atributos físicos e químicos do solo e outros conjuntos de informações, foi verificada a possibilidade de relacionar a variabilidade desses atributos com as sub-regiões que se pretendia identificar na área, ou se os fatores climáticos, como os índices de precipitação pluviométrica, podiam demonstrar alguma influência na produtividade em virtude da variabilidade espacial dos atributos de solo nestas sub-regiões. Foram utilizados programas geoestatísticos para estudar o nível de dependência e a estrutura da variabilidade espacial dos dados de produtividade e de atributos de solo. As análises de comportamento da produtividade e a sua classificação pela análise de agrupamentos, bem como o mapeamento de atributos do solo, foram realizados com a utilização de um sistema de informação geográfica (SIG). Os resultados obtidos demonstraram que os dados de produtividade expressaram uma dependência espacial bastante... .
Yield maps analysis, into precision farming context, is one of the resources used in order to understand and manage the spatial variability of crop's yield and quality. Corn and soybean yield maps obtained from a commercial yield mapping system for three seasons (1998, 1999 and 2000) were studied and classified by a clustering analysis technique using all seasons dataset mixed in a composite image. The aim of this project was to associate some variation trends on the yield behavior to the clusters obtained, in order to characterize these regions with different behaviors within the area. Using a dataset of physical and chemical soil characteristics from a grid soil survey, it was verified the possibility of relating the soil attributes variability to the sub-regions identified in the area. It was still investigated if rainfall index could demonstrate some influence on yield due to spatial variability of the soil attributes on these sub-regions. It was used a geostatistical software for studying the dependence level and the spatial variability framework of yield and soil attributes data. Soil attributes mapping, as well yield behavior analysis and its classification by the clustering analysis were made using a geographical information system (GIS). The results showed that the yield datasets expressed a consistent spatial dependence, which correlation distances ranged from 30 to 40 meters. The spatial variability degree expressed by the structural semivariance contribution index (%C) achieved a high variability level to Corn on 1998 season and medium variability on Soybean 1999 and Corn 2000 season. The clustering analysis technique applied to the three yield maps datasets became possible split the area in four sub-regions. The combination of the maps classified by yield levels allowed defining four yield behavior classes expressively related to the obtained... (Complete abstract, click electronic address below).
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Queiroz, Simone de Castro [UNESP]. "Função Gompertz aplicada a modelagem de produção do biogás em biodigestor tipo batelada." Universidade Estadual Paulista (UNESP), 2001. http://hdl.handle.net/11449/90699.
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queiroz_sc_me_botfca.pdf: 219590 bytes, checksum: 11caae545555dffe208b4feb070748f0 (MD5)O presente trabalho tem por objetivo a modelagem estatística da produção de biogás, utilizando-se de modelos de regressão não-linear, a partir do estudo da biodigestão anaeróbia de três tipos de camas de frangos de corte (napier, mistura de napier+maravalha e maravalha), obtidos após um ciclo de criação e após reutilização em um segundo ciclo. Para cada ciclo, foram obtidos dados relativos às produções médias de biogás, apresentados sob forma de totais semanais, em m3 e em valores acumulados para cada substrato. Foi feita a modelagem estatística, a partir dos tratamento definidos, utilizando-se do modelo Gompertz de regressão não-linear, segundo duas linhas metodológicas distintas. Inicialmente, foram considerados modelos de regressão não-linear somente com um componente determinístico e, posteriormente, com dois componentes (mistura). Foram estudadas as propriedades amostrais dos estimadores através de simulações sob a ótica distribucional. A aproximação de uma Gompertz do modelo estatístico proposto para o volume de biogás para os três tipos de camas de frangos mostrou-se adequada em todas situações experimentais, permitindo estimar os parâmetros envolvidos no modelo, utilizando-se técnicas não-paramétricas. O modelo com mistura de duas Gompertz proporcionou bom ajuste aos dados, mas com dificuldades de convergência no processo de estimação dos parâmetros, no qual ocorreu a heterocedasticidade dos erros, isto é, a parte aleatória do modelo não teve variância constante.
In this work, the Gompertz model was used to fit the biogas production in batch biodigestor obtained from the anaerobic digestion of three poultry litter kinds (elephant grass, elephant grass + wood shavings and wood shavings). Two strategies of modeling was proposed, i.e., using one and two (mixture) deterministic components in the statistical models. Results showed that Gompertz model with just a deterministic component fits very well, and allowed to compare the estimated parameters among the poultry litter kinds by nonparametric techniques . Although the models with the mixture fits better than the other one, there are some problems with the convergence processes and the parameter estimation.
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Cardoso, Guilherme Berriel [UNESP]. "Potencial de redução de consumo de energia elétrica em entreposto frigorífico: um estudo de caso." Universidade Estadual Paulista (UNESP), 2004. http://hdl.handle.net/11449/90799.
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cardoso_gb_me_bauru.pdf: 4100017 bytes, checksum: 472027856f4836299a15fb55465e3ec2 (MD5)Becar - Ind. e Com. de Refrigeracao Ltda
Com o risco de blecaute de energia elétrica que o Brasil enfrentou durante o período de racionamento de energia elétria (2001-2002), devido ao elevado aumento do consumo após o Plano Real (o aumento na geração de energia elétrica cada vez maior, existem grandes possibilidades tanto na conservação como recuperação da energia elétrica. Esse trabalho trata do potencial de redução de consumo de energia elétrica em um entreposto frigorífico. Foi realizado um levantamento do custo da energia elétrica no consumo de três câmaras frigoríficas, através do levantamento da potência elétrica consumida nas câmaras multiplicada pelo preço do kWh praticado na tarifa convencional, na qual a empresa está atualmente enquadrada. Esta é a situação atual do entreposto. Foi proposta uma mudança de equipamentos nas câmaras frigoríficas, por equipamentos...
With the risk of electrical energy blackout that Brazil during the period of electricity saving (2001-2002), due to the high increase of the consumption after Real Plane (the increase in the electricity generation didn't follow the consumption increase) and the rising cost of electricity, there are great possibilities booth in the conservation and in the retrieval of electricity. This paper tells of the potential of reduction in electricity consumption in a slaughterhouse refrigerator distribution center. There was a mesurement in the cost of electricity in the consumption of theree slaughterhouse refrigerator, through the measurement of the electrical power consumed in the refrigerator multiplied by the cost of kWh in the conventional rate, where the company currently is operating. This is the current situation of the distribution center... (Complete abstract click electronic access below)
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Teixeira, Lucas André [UNESP]. "Análise dos projetos ambientais desenvolvidos em um bairro de Bauru (SP) sob a perspectiva educativa." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/90899.
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teixeira_la_me_bauru.pdf: 1300339 bytes, checksum: 092143a424d8fdcec87d55f9716d15e9 (MD5)Secretaria da Educação de SP
Partindo do pressuposto de que a educação ambiental é um processo educativo que objetiva a instrumentalização dos sujeitos para o enfrentamento das verdadeiras causas da crise sócio-ambiental, visando a emancipação das condições determinadas pelo modo de produção atual, agente determinante da crise sócio-ambiental a que está submetida a humanidade, este trabalho propõe-se analisar trabalhos que foram realizados em um bairro popular, objetivando identificar e compreender as diferentes abordagens filosófico-políticas que se expressam nas ações ambientais, ao passo em que pretendemos identificar os fatores indicativos de impactos qualitativos que essas ações proporcionaram na organização do ensino escolar e na comunidade, entendendo-as como espaço educativo. Por meio da análise dos Projetos Ambientais que envolveram a temática ambiental e que foram realizados por diversos segmentos da sociedade, tais como: Universidades, Poder Público, Organizações não-governamentais e Associação de Moradores, este trabalho pretende produzir conhecimentos que contribuam para o enfrentamento da problemática ambiental, buscando o aprofundamento da reflexão de alguns de seus princípios na perspectiva da educação ambiental crítica.
Assuming that environmental education is an educational process which aims at exploitation of the subjects to facing the real causes of social and environmental crisis, to the emancipation of the determined conditions by the current mode of production, a key agent of social and environmental crisis in that the humanity is the subject, this work proposes to examine works have done in a popular district. It aims to identify and understand the different philosophical and politics approaches, those are expressed in environmental actions, while we intend to identify the qualitative impacts those actions provided in the scholl daily and in the community, understanding them as educational spaces. Through the analysis of Environmental Projects those involved the environment thematic and have been done by some segments of society, such as: Universities, Public Authorities, Nongovernmental organizations and Associations of residents. This work intends to produce knowledge to help facing the environmental problem, seeking to deep the reflection of some of its principles under the critical environmental education.
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Mussolini, Ana Flávia [UNESP]. "Reflexões de futuros professores de matemática sobre uma prática educativa utilizando planilhas eletrônicas." Universidade Estadual Paulista (UNESP), 2004. http://hdl.handle.net/11449/90999.
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mussolini_af_me_rcla.pdf: 306703 bytes, checksum: 2844e21933fc8c32b8ed7b5f32ed2d19 (MD5)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Esta pesquisa trata da Formação Inicial de Professores de Matemática, em particular sobre o uso de tecnologia informática. Sabendo da problemática existente nos cursos de graduação, como, por exemplo, a desarticulação entre teoria e prática, entre formação universitária e realidade escolar, deteve-se na seguinte questão: Quais são as perspectivas, expectativas e dificuldades que os futuros professores apresentam quando refletem sobre uma prática educativa utilizando planilhas eletrônicas na escola básica?. A pesquisa contou com a participação de dois futuros professores de Matemática da UNESP de Rio Claro. Foram realizados três encontros de planejamento, dez encontros de intervenção em uma escola pública, e dez encontros de reflexão, que ocorreram sempre após cada intervenção. Os licenciandos tiveram a oportunidade de expor suas idéias sobre as experiências realizadas e, a partir de uma análise à luz do referencial teórico, foram extraindo temas que se referem às suas expectativas, perspectivas e dificuldades. Entre eles, a gestão da sala de aula e a transposição de conteúdo, a complexidade da sala de aula, como eles percebem os alunos, as condições de trabalho na escola, ser professor e o uso de tecnologia informática.
This research addresses the pre-service mathematics teacher education, in particular their practice with computer. Considering the problems concerning teacher education courses - as, for instance, the disarticulation between the theory and the practice, and between the university education and the school reality - it was formulated the following research question: What are the perspectives, expectations and difficulties that the future teachers experience when they reflect on an educational practice using spreadsheets at the basic school? The research was developed in collaboration with two future mathematics teachers from UNESP at Rio Claro, São Paulo, Brazil. It was organized three planning meetings, ten intervention meetings in a public school, and ten reflection meeting, that always took place right after each intervention meeting. The reflection meetings were videoed and transcribed. The data were analyzed with reference to the literature. Themes were identified that could be referred to their expectation, perspectives, and difficulties. These themes included: the teaching in the classroom and the transposition of the contents; the complexity of the classroom environment; the interaction with the students; the school working conditions; being a teacher; and the use of computers.
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Tasissa, Abiy (Abiy Fekadu). "On the formation of Friedlander waves in a compressed gas driven shock tube." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/90799.
Анотація:
Thesis: S.M., Massachusetts Institute of Technology, Department of Aeronautics and Astronautics, 2014.Cataloged from PDF version of thesis.
Includes bibliographical references (pages 71-73).
Compressed gas driven shock tubes have become popular as a laboratory-scale replacement for field blast tests. The well-known initial structure of the Riemann problem eventually evolves into a shock structure resembling a Friedlander wave. In this thesis, we develop an analytical model to predict its key characteristics: location where the wave first forms, peak over-pressure, decay time and impulse. The approach is based on combining the solutions of the two different types of wave interactions that arise in the shock tube after the family of rarefaction waves in the Riemann solution interacts with the closed end of the tube. The results of the analytical model are verified against numerical simulations obtained with a finite volume method. The model furnishes a rational approach to relate shock tube parameters to desired blast wave characteristics, and thus constitutes a useful tool for the design of shock tubes for blast testing.
by Abiy Tasissa.
S.M.
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Oswald, W. Andrew (William Andrew). "Understanding technology development processes theory & practice." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/90699.
Анотація:
Thesis: S.M. in Engineering and Management, Massachusetts Institute of Technology, Engineering Systems Division, System Design and Management Program, 2013.Cataloged from PDF version of thesis.
Includes bibliographical references (pages 75-77).
Technology development is hard for management to understand and hard for practitioners to explain, however it is an essential component of innovation. While there are standard and predictable processes for product development, many of these techniques don't apply well to technology development. Are there common processes for technology development that can make it predictable, or is it unpredictable like basic research and invention? In this thesis, after building a foundation by looking at product development processes, I survey some of the literature on technology development processes and compare them to a handful of case studies from a variety of industries. I then summarize the observations from the cases and build a generic model for technology development that can be used to provide insights into how to monitor and manage technology projects. One of the observations from the product development literature is that looping and iteration is problematic for establishing accurate schedules which becomes one of the fundamental disconnects between management and engineering. Technologists rely heavily on iteration as a tool for gaining knowledge and combined with other risks, technology development may appear "out of control". To mitigate these risks, technologists have developed a variety of approaches including: building a series of prototypes of increasing fidelity and using them as a form of communication, simultaneously developing multiple technologies as a hedge against failure or predicting and developing technologies they think will be needed outside of formal channels. Finally, I use my model to provide some insights as to how management can understand technology development projects. This gives technologists and non-technical managers a common ground for communication.
by W. Andrew Oswald.
S.M. in Engineering and Management
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Conrad, Patrick Raymond. "Accelerating Bayesian inference in computationally expensive computer models using local and global approximations." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/90599.
Анотація:
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Aeronautics and Astronautics, 2014.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 129-138).
Computational models of complex phenomena are an important resource for scientists and engineers. However, many state-of-the-art simulations of physical systems are computationally expensive to evaluate and are black box-meaning that they can be run, but their internal workings cannot be inspected or changed. Directly applying uncertainty quantification algorithms, such as those for forward uncertainty propagation or Bayesian inference, to these types of models is often intractable because the analyses use many evaluations of the model. Fortunately, many physical systems are well behaved, in the sense that they may be efficiently approximated with a modest number of carefully chosen samples. This thesis develops global and local approximation strategies that can be applied to black-box models to reduce the cost of forward uncertainty quantification and Bayesian inference. First, we develop an efficient strategy for constructing global approximations using an orthonormal polynomial basis. We rigorously construct a Smolyak pseudospectral algorithm, which uses sparse sample sets to efficiently extract information from loosely coupled functions. We provide a theoretical discussion of the behavior and accuracy of this algorithm, concluding that it has favorable convergence characteristics. We make this strategy efficient in practice by introducing a greedy heuristic that adaptively identifies and explores the important input dimensions, or combinations thereof. When the approximation is used within Bayesian inference, however, it is difficult to translate the theoretical behavior of the global approximations into practical controls on the error induced in the resulting posterior distribution. Thus, the second part of this thesis introduces a new framework for accelerating MCMC algorithms by constructing local surrogates of the computational model within the Metropolis-Hastings kernel, borrowing ideas from deterministic approximation theory, optimization, and experimental design. Exploiting useful convergence characteristics of local approximations, we prove the ergodicity of our approximate Markov chain and show that it samples asymptotically from the exact posterior distribution of interest. Our theoretical results reinforce the key observation underlying this work: when the likelihood has some local regularity, the number of model evaluations per MCMC step can be greatly reduced, without incurring significant bias in the Monte Carlo average. We illustrate that the inference framework is robust and extensible by describing variations that use different approximation families, MCMC kernels, and computational environments. Our numerical experiments demonstrate order-of-magnitude reductions in the number of forward model evaluations used in representative ODE or PDE inference problems, in both real and synthetic data examples. Finally, we demonstrate the local approximation algorithm by performing parameter inference for the ice-ocean coupling in Pine Island Glacier, Antarctica. This problem constitutes a challenging domain for inference and an important application in climate science. We perform simulated inference, comparing synthetic data to predictions from the MIT General Circulation Model, a state-of-the-art ocean simulation. The results reveal some information about parameter sensitivity, but we ultimately conclude that richer data is necessary to constrain the model parameters. In this example, applying our approximation techniques reduced the cost of the inference by a factor of five to ten, taking weeks instead of months, providing evidence that our techniques can make Bayesian inference on large-scale computational models more tractable.
by Patrick Raymond Conrad.
Ph. D.
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Sappelt, Ruth. "We live here : tenants and the Massachusetts Public Housing Reform debate." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/90099.
Анотація:
Thesis: M.C.P., Massachusetts Institute of Technology, Department of Urban Studies and Planning, 2014.Cataloged from PDF version of thesis.
Includes bibliographical references (pages 14-15).
The embezzlement and corruption scandal surrounding the director of a local Massachusetts housing authority in late 2011 spurred a heated public debate about governance and efficiency in the state-funded public housing system. Governor Patrick, state agency heads, public and affordable housing professionals and experts and tenant advocates debated the degree to which the system should be centralized. Eventually, this debate was framed within the parameters of two opposing bills submitted to the state legislature. The Legislature's Committee on Housing took up the issue in June 2013 and will submit a third bill, widely considered to be the decisive measure, towards the end of the 2014 session. Tenant interests were largely absent in this debate. While existing regulations require housing authorities to encourage and fund local tenant organizations, many tenant representatives face retaliation from administrators. In this documentary film thesis, tenants whose organizing efforts have been suppressed discuss how they support one another, overcome stigma and advocate for the interests of their neighbors.
by Ruth Sappelt.
M.C.P.
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David, LaKisha T. (LaKisha Tawanda). "A case for public sanitation with on-site treatment in Ghana." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/90199.
Анотація:
Thesis: M.C.P., Massachusetts Institute of Technology, Department of Urban Studies and Planning, 2014.Cataloged from PDF version of thesis.
Includes bibliographical references (pages 57-60).
According to the WHO/UNICEF Joint Monitoring Programme (JMP), 14% of the population in Ghana use improved sanitation facilities and 59% use shared facilities. The objective of this thesis is to offer a situational analysis of public sanitation in Ghana by addressing both access to sanitation and bio-digestion on-site waste treatment for one non-profit organization, Pure Home Water, to improve access to sanitation in the Northern Sector of Ghana. Based on the neighborhood, customary, and political context of Ghana, I recommend the construction of new public sanitation facilities, the conversion of existing household toilets to the biodigester systems, and making bio-digester systems a standard technical model while creating local ownership of the technology. In addition, I recommend evaluating the status quo to address the needs of vulnerable groups, addressing hygiene needs as standard, and appealing to the local government's business sense.
by LaKisha T. David.
M.C.P.
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Pinheiro, Cláudia Ramos. "Avaliação da infiltração bacteriana corono-apical de canais radiculares obturados com diferentes tipos de cimentos endodônticos /." Araraquara : [s.n.], 2008. http://hdl.handle.net/11449/90399.
Анотація:
Orientador: Idomeo Bonetti FilhoBanca: Carlos Benatti Neto
Banca: Antonio Carlos Bombana
Resumo: Avaliamos a infiltração coroa-ápice da bactéria Enterococcus faecalis em incisivos centrais bovinos instrumentados e obturados com os cimentos endodônticos AH Plus, Endofill, Epiphany, Acroseal e o cimento experimental à base do Polímero da mamona (Polifil). Foi confeccionado um dispositivo a ser adaptado na porção inferior de tubos de centrífuga, Eppendorf. As raízes, previamente obturadas, foram inseridas nesse dispositivo até que 5mm se projetasse para fora do tubo plástico. A junção entre o tubo e a raiz foi selada com araldite, assim como a porção da raiz, externa ao recipiente, excluindo-se 1 mm ao redor do forame apical. O dispositivo Eppendorf e raiz obturada foram fixados em frasco tipo penicilina, contendo caldo .Brain heart infusion.. Com auxílio de uma pipeta, 1mL da bactéria foi transferido ao caldo B.H.I. e 400 µL de uma cultura recente foram transferidos para a porção superior do tubo. Durante 64 dias, a infiltração bacteriana era detectada através da turvação do caldo. Os resultados foram submetidos à análise estatística. Foi utilizado o método não-paramétrico de Kaplan-Meier e o teste de Kruskal-Wallis, complementado por comparações múltiplas pelo teste de Dunn. Adotou-se o nível de significância de 5%. Os cimentos AH Plus e Endofill apresentaram resistência à infiltração bacteriana significativamente menor do que o Polifil, mas estatisticamente equivalentes entre si. Os cimentos Epiphany e Acroseal deram resultados intermediários e equivalentes, mas sem diferença estatisticamente significante em relação aos outros cimentos.
Abstract: This study compared some of the endodontic sealers sealing ability (AH Plus, Epiphany, Acroseal, Endofill and Polifil (a castor oil-based experimental sealer) using the active lateral condensation technique, through a bacterial test, during 64 days. One hundred bovine incisors were selected and divided into five experimental groups and two control groups (negative and positive ones). The teeth were cleaned and shaped by the step-back technique, then, they were filled with the endodontic sealers and stored in (100%) wet environment. The roots were impermeabilized with araldite glue, adapted into an eppendorf microtube and sterilized by ethylen oxide gas. The root/ eppendorf microtube was added to penicillin flasks containing 6mL of BHI broth kept at 37º C for 4 days to confirm sterilization. After this period, 400µL of Enterococcus faecalis ATCC 29212 were inserted at the upper portion of the eppendorf microtube. Daily leakage was evaluated through the broth turbidy. The results were submitted to the statistical analysis (Kaplan-Meier method as well as Kruskal-Wallis' and Dunn's tests). AH Plus and Endofill sealers were statistically equivalent concerning the sealing property, showing less resistance to the bacterial leakage than Polifil, while Acroseal and Epiphany had similar and intermediate behavior, but without numerical significance when compared to the other sealers.
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23
Costa, Nanci Aparecida. "O uso da mídia e a presença dos gêneros textuais no processo ensino-aprendizagem : uma análise do material didático - cadernos do aluno e do professor - de língua portuguesa do estado de São Paulo /." Rio Claro : [s.n.], 2012. http://hdl.handle.net/11449/90099.
Анотація:
Orientador: Marcia Reami PechulaBanca: Maria Augusta Hermengarda Wurthmann Ribeiro
Banca: Maria Inês Ghilardi Lucena
Resumo: O objetivo desta pesquisa de mestrado é estudar a questão do uso das mídias e sua inserção no processo de ensino-aprendizagem de Língua Portuguesa, com o intuito de, no primeiro momento, expor os princípios epistemológicos e históricos que dão suporte teórico para tal temática. A partir desta base teórica, estudar como ocorre a presença destes elementos no material em circulação na rede pública de ensino do Estado de São Paulo. Tecendo, desta forma, discussões sobre a influência dos meios de comunicação na educação e na cultura dos alunos. Finalmente, apresentar qualitativamente a presença do uso das mídias nas apostilas de Língua Portuguesa em circulação no ensino público do Estado de São Paulo, discorrendo, a partir de elementos retirados do próprio material trabalhado em sala de aula, a presença dos gêneros textuais no processo de ensino-aprendizagem, utilizando como base a mídia. Assim, mostrando, a distribuição dos gêneros (textuais e midiáticos) em cada uma das quatro apostilas estudadas pelos alunos e utilizadas pelos professores na série final de sua formação no Ensino Médio
Abstract: The main goal of this research is to study the issue of media utilization and its insertion on the process of learning-teaching of the Portuguese Language to, primarily, expose the epistemological e historical principles that give theoretical support to that theme. From this theoretical basis, to study how the presence of these elements occur at the circulating material on the public teaching of the State of São Paulo. Bringing, thus, discussions about the influence of the communicational means on education e student culture. Finally, to present qualitatively the presence of media utilization on books of Portuguese Language in circulation at the public teaching of the State of São Paulo, bringing, from the elements taken from the material used in class, the presence of textual genres on the teaching-learning process, using as basis the media. This way, showing, the distribution of genres (textual and mediatic) on each of the four books studied by the students and used by the teachers on the final grade of their formation in High School
Mestre
24
Rodrigues, João Batista Tolentino 1966. "Variabilidade espacial e correlações entre atributos de solo e produtividade na agricultura de precisão /." Botucatu : [s.n.], 2002. http://hdl.handle.net/11449/90599.
Анотація:
Orientador: Célia Regina Lopes ZimbackResumo: A análise de mapas de produtividade, no contexto da agricultura de precisão, é um dos recursos utilizados na tentativa de compreender e manejar a variabilidade espacial da produtividade e da qualidade das culturas. Mapas de produtividade de milho e de soja gerados por um sistema comercial de monitoramento de colheita para as safras de 1998, 1999 e 2000 foram estudados e submetidos a um processo de classificação através da técnica de análise de agrupamento para o conjunto de dados dos três anos reunidos em uma imagem composta. Objetivou-se, a partir dos agrupamentos obtidos, associar algumas tendências de variação no comportamento da produtividade que pudessem caracterizar essas regiões com comportamentos diferenciados dentro da área. Com o auxílio de um levantamento de atributos físicos e químicos do solo e outros conjuntos de informações, foi verificada a possibilidade de relacionar a variabilidade desses atributos com as sub-regiões que se pretendia identificar na área, ou se os fatores climáticos, como os índices de precipitação pluviométrica, podiam demonstrar alguma influência na produtividade em virtude da variabilidade espacial dos atributos de solo nestas sub-regiões. Foram utilizados programas geoestatísticos para estudar o nível de dependência e a estrutura da variabilidade espacial dos dados de produtividade e de atributos de solo. As análises de comportamento da produtividade e a sua classificação pela análise de agrupamentos, bem como o mapeamento de atributos do solo, foram realizados com a utilização de um sistema de informação geográfica (SIG). Os resultados obtidos demonstraram que os dados de produtividade expressaram uma dependência espacial bastante... (Resumo completo, clicar acesso eletrônico abaixo).
Abstract: Yield maps analysis, into precision farming context, is one of the resources used in order to understand and manage the spatial variability of crop's yield and quality. Corn and soybean yield maps obtained from a commercial yield mapping system for three seasons (1998, 1999 and 2000) were studied and classified by a clustering analysis technique using all seasons dataset mixed in a composite image. The aim of this project was to associate some variation trends on the yield behavior to the clusters obtained, in order to characterize these regions with different behaviors within the area. Using a dataset of physical and chemical soil characteristics from a grid soil survey, it was verified the possibility of relating the soil attributes variability to the sub-regions identified in the area. It was still investigated if rainfall index could demonstrate some influence on yield due to spatial variability of the soil attributes on these sub-regions. It was used a geostatistical software for studying the dependence level and the spatial variability framework of yield and soil attributes data. Soil attributes mapping, as well yield behavior analysis and its classification by the clustering analysis were made using a geographical information system (GIS). The results showed that the yield datasets expressed a consistent spatial dependence, which correlation distances ranged from 30 to 40 meters. The spatial variability degree expressed by the structural semivariance contribution index (%C) achieved a high variability level to Corn on 1998 season and medium variability on Soybean 1999 and Corn 2000 season. The clustering analysis technique applied to the three yield maps datasets became possible split the area in four sub-regions. The combination of the maps classified by yield levels allowed defining four yield behavior classes expressively related to the obtained... (Complete abstract, click electronic address below).
Mestre
25
Giachini, Camillo Ferrarezi 1987. "Desempenho operacional de uma colhedora de cana-de-açucar ( Saccarum spp.) em função dos turnos de trabalho /." Botucatu :, 2012. http://hdl.handle.net/11449/90499.
Анотація:
Orientador: Carlos Antonio Gamero.Coorientador: Kléber Pereira Lanças
Banca: Paulo Roberto Arbex Silva
Banca: Carlos Eduardo Angeli Furlani
Resumo: A agricultura nos últimos anos vem sofrendo pressões para a modificação de suas técnicas visando o aumento da produtividade, redução dos custos de de produção e a preocupação com o ambiente. Em busca de atingir todos estes fatores, a cultura da cana-de-acucar foi em busca da modernização que ocorreram principlamente no campo.Um gande avanço tecnologico para a producção da cana-de-acúcar foi a substitição do sistema de colheita manual para o sistema mecanizado. A colheita mecanizada passa a suprir a mão de obra utilizada no corte que estava se tornando escassa, além de possibilitar um rendimento na colheita e uma menor agressão ao ambiente uma vez que a queima do canavial deixou de ser utilizada. Por estes fatore o presente trabalho teve por objetivo avaliar o desempenho operacional de uma colhedora de cana-de-açúcar sem queima prévia do canavial durante os três turnos de trabalho da mesma. O ensaio foi realizado na Usina Santa Cândida, pertencente ao Grupo Tonon Biotecnologia,localizada no municipio de Bocaina ,Região Centro Oeste do Estado de São Paulo. O canavial avaliado foi caracterizado... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: Agriculture in recent years has been facing pressure to change their techniques in order to increase productivity, reduce production costs and concern for the environment. In seeking to achieve all these factors, the culture of sugar cane was looking for upgrades that occurred mainly in the field. A major technological breakthrough for the mechanized system. Mechanized harvesting is to supply the labor used in the cut that was becoming scarce, and enables at yields at harvest and less aggression to the environment since the burning of sugarcane is no longer used. For these reasons the present study was to evaluate the operating performance of a harvester for cane sugar without previous burning of sugarcane during the three work shifts the same. The test was conducted at Santa Candida. Plant belonging to the group Tonon Bioenergy, located in the municipality of Bocaina, Midwest Region of São Paulo. The sugarcane was assessed... (Complete abstract click electronic access below)
Mestre
26
Cardoso, Guilherme Berriel. "Potencial de redução de consumo de energia elétrica em entreposto frigorífico : um estudo de caso /." Bauru : [s.n.], 2004. http://hdl.handle.net/11449/90799.
Анотація:
Orientador: Paulo Cesar RazukBanca: Antonio Moreira dos Santos
Banca: Vicente Luiz Scavon
Resumo: Com o risco de blecaute de energia elétrica que o Brasil enfrentou durante o período de racionamento de energia elétria (2001-2002), devido ao elevado aumento do consumo após o Plano Real (o aumento na geração de energia elétrica cada vez maior, existem grandes possibilidades tanto na conservação como recuperação da energia elétrica. Esse trabalho trata do potencial de redução de consumo de energia elétrica em um entreposto frigorífico. Foi realizado um levantamento do custo da energia elétrica no consumo de três câmaras frigoríficas, através do levantamento da potência elétrica consumida nas câmaras multiplicada pelo preço do kWh praticado na tarifa convencional, na qual a empresa está atualmente enquadrada. Esta é a situação atual do entreposto. Foi proposta uma mudança de equipamentos nas câmaras frigoríficas, por equipamentos... (Resumo completo, lcicar acesso eletrônico abaixo)
Abstract: With the risk of electrical energy blackout that Brazil during the period of electricity saving (2001-2002), due to the high increase of the consumption after Real Plane (the increase in the electricity generation didn't follow the consumption increase) and the rising cost of electricity, there are great possibilities booth in the conservation and in the retrieval of electricity. This paper tells of the potential of reduction in electricity consumption in a slaughterhouse refrigerator distribution center. There was a mesurement in the cost of electricity in the consumption of theree slaughterhouse refrigerator, through the measurement of the electrical power consumed in the refrigerator multiplied by the cost of kWh in the conventional rate, where the company currently is operating. This is the current situation of the distribution center... (Complete abstract click electronic access below)
Mestre
27
Quintanilha, Edson de Castro. "Representações de estudantes do curso de Pedagogia e de professores da rede pública sobre alunos dos anos iniciais /." Presidente Prudente : [s.n.], 2010. http://hdl.handle.net/11449/90199.
Анотація:
Resumo: Este trabalho, ligado à linha de pesquisa "Políticas Públicas, Organização Escolar e Formação de Professores", teve por objetivo investigar e comparar as representações sociais de estudantes do Curso de Pedagogia da FCT/UNESP e dos professores formados em Cursos de Pedagogia, sobre os alunos dos anos iniciais do Ensino Fundamental da rede municipal de ensino, analisando sua percepção sobre a interferência dessas representações no desenvolvimento do trabalho docente. Para atingir esse objetivo, procuramos responder às perguntas: Que representações sociais os estudantes do Curso de Pedagogia e os professores possuem do aluno dos anos iniciais da escola pública com os quais trabalham ou poderão vir a trabalhar? Estas representações apresentam diferenças após o início da prática docente? Elas podem interferir no desenvolvimento do trabalho docente? Apoiamo-nos, para o desenvolvimento desse trabalho, na teoria das representações sociais de Serge Moscovici. A partir do nosso referencial teórico coletamos os dados necessários, junto aos participantes da pesquisa, por meio de questionário contendo solicitação de evocações sobre "aluno ideal" e "aluno da escola pública" e questões objetivas e subjetivas, permitindo uma triangulação para confirmação das representações pesquisadas. A análise dos dados coletados possibilitou-nos identificar as representações sociais de estudantes do Curso de Pedagogia e dos professores sobre os alunos das séries iniciais da rede pública municipal e refletir sobre os aspectos cognitivos, comportamentais/afetivos e socioculturais nelas contidos. Em seguida analisamos as expectativas docentes nascidas das representações e sua possível influência no sucesso escolar do aluno, valendo-nos da teoria da profecia autorrealizadora ... (Resumo completo, clicar acesso eletrônico abaixo)Abstract: The present paper is connected to the research line entitled "Public Policies, Scholar Organization and Teachers' Formation". The main of this study is to investigate and compare social representations of Pedagogy students' from FCT/UNESP and teachers' graduated at Pedagogy about elementary school students from municipal schools. Besides, it aims to analyze how their perception interferes into their practice. In order to reach such objectives we intended to ask the following questions: What social representations Pedagogy students and teachers have about elementary school students from municipal schools with whom they will work? Are such representations different after they start to work as teachers? Can they interfere into teachers' work? The theoretical base of this paper is Social Representations Theory by Serge Moscovici. The data were collected through questionnaire with objective and subjective questions related to the "ideal student" and the "student from public school", which provides us to investigate the researched representations. Through data analysis it was possible to identify social representations of Pedagogy students' and teachers' about elementary school students from municipal schools. Thus, it was also possible to think about cognitive, behavior/affective and sociocultural aspects inserted into such representations. After that, we analyzed teachers' expectations brought from their representation and the its possible influence in students' scholar success, according to self-performing theory ... (Complete abstract click electronic access below)
Orientador: Yoshie Ussami Ferrari Leite
Coorientador: Maria Suzana de Stefano Menin
Banca: Claudia Maria de Lima
Banca: Alda Judith Alves Mazzotti
Mestre
28
Abrantes, Aline Reck Padilha. "Instituição ou instituído? : análise de uma prática escolar de inclusão /." Araraquara : [s.n.], 2007. http://hdl.handle.net/11449/90299.
Анотація:
Orientador: Maria Cristina Bergonzoni StefaniniBanca: Luci Regina Muzzeti
Banca: Taciana Mirna Sandrano
Resumo: A experiência profissional e os impasses enfrentados no cotidiano de trabalho atual, quando se trata de crianças com algum diagnóstico a serem incluídas na escola regular, instigaramnos a realizar o presente estudo. Partindo do princípio de que a inclusão implica no trabalho de toda instituição escolar é que buscamos na Pedagogia Institucional sustentação para nossa pesquisa. A Pedagogia Institucional, corpo de conhecimentos teóricos que, articulado a prática pedagógica, transforma a classe num laboratório de trabalho constante vem a ser a perspectiva da leitura da prática da Escola de Educação Infantil e Ensino Fundamental Centro Integrado de Desenvolvimento - CID. Os sujeitos foram todos os profissionais e professores desta escola, os alunos do último ano da educação infantil, alunos da primeira série e alunos da última série do ensino fundamental, os pais e uma profissional da Escola Nossa Senhora do Bom Conselho, escola que recebe alunos egressos do CID. Os dados coletados constituíram os seguintes focos de análise: 1. A escola como promotora da unidade. 2. A escola como promotora da autonomia. 3. A troca com os pais. 4. A escola como promotora do diálogo com a sociedade. 5. O trabalho em grupo. 6. A escuta como exercício da ética. 7. A equipe interdisciplinar como suporte. 8. A prática da avaliação. Após analise e discussão reflexiva, consideramos que o cerne da inclusão é a prática instituída no cotidiano da escola e, pensamos que a relevância desta pesquisa está na possibilidade de contribuir com aqueles setores que pretendem instituir a inclusão.
Abstract: Professional experience and difficulties faced in the routine of current work, concerning children with some kind of diagnostic to be included in the regular school, encouraged us to accomplish the present work. Our work is supported by Institutional Pedagogy for we think that inclusion is the work of the whole school institution. Institutional Pedagogy, theoretical knowledge which when related to pedagogical practice turns the classroom into a laboratory of constant work, is the perspective from what practiced is understood at the Elementary and Middle school CID (Centro Integrado de Desenvolvimento). The subjects were all professionals and teachers from this school, students from the last grade of elementary school and from the first and last grade of middle school, parents and one professional from Bom Conselho school, which admits students from CIC. The collected data were related to the following focus of analysis: 1. The school as unity provider; 2. The school as autonomy provider; 3. Connections between parents and school; 4. The school as dialogue provider in the society; 5. The group work; 6. Hearing as ethics exercise; 7. The interdisciplinary team as support and 8. Evaluation practice. After the analysis and discussion, we have considered the practice instituted in the school routine the key for the inclusion. We think that the relevance of this study is in the possibility of contributing to those sectors which intend to institute the inclusion.
Mestre
29
Queiroz, Simone de Castro 1960. "Função Gompertz aplicada a modelagem de produção do biogás em biodigestor tipo batelada /." Botucatu : [s.n.], 2001. http://hdl.handle.net/11449/90699.
Анотація:
Orientador: José Raimundo de Souza PassosBanca: Jorge de Lucas Junior
Banca: Maria Teresinha T. Tornero
Resumo: O presente trabalho tem por objetivo a modelagem estatística da produção de biogás, utilizando-se de modelos de regressão não-linear, a partir do estudo da biodigestão anaeróbia de três tipos de camas de frangos de corte (napier, mistura de napier+maravalha e maravalha), obtidos após um ciclo de criação e após reutilização em um segundo ciclo. Para cada ciclo, foram obtidos dados relativos às produções médias de biogás, apresentados sob forma de totais semanais, em m3 e em valores acumulados para cada substrato. Foi feita a modelagem estatística, a partir dos tratamento definidos, utilizando-se do modelo Gompertz de regressão não-linear, segundo duas linhas metodológicas distintas. Inicialmente, foram considerados modelos de regressão não-linear somente com um componente determinístico e, posteriormente, com dois componentes (mistura). Foram estudadas as propriedades amostrais dos estimadores através de simulações sob a ótica distribucional. A aproximação de uma Gompertz do modelo estatístico proposto para o volume de biogás para os três tipos de camas de frangos mostrou-se adequada em todas situações experimentais, permitindo estimar os parâmetros envolvidos no modelo, utilizando-se técnicas não-paramétricas. O modelo com mistura de duas Gompertz proporcionou bom ajuste aos dados, mas com dificuldades de convergência no processo de estimação dos parâmetros, no qual ocorreu a heterocedasticidade dos erros, isto é, a parte aleatória do modelo não teve variância constante.
Abstract: In this work, the Gompertz model was used to fit the biogas production in batch biodigestor obtained from the anaerobic digestion of three poultry litter kinds (elephant grass, elephant grass + wood shavings and wood shavings). Two strategies of modeling was proposed, i.e., using one and two (mixture) deterministic components in the statistical models. Results showed that Gompertz model with just a deterministic component fits very well, and allowed to compare the estimated parameters among the poultry litter kinds by nonparametric techniques . Although the models with the mixture fits better than the other one, there are some problems with the convergence processes and the parameter estimation.
Mestre
30
Teixeira, Lucas André. "Análise dos projetos ambientais desenvolvidos em um bairro de Bauru (SP) sob a perspectiva educativa /." Bauru : [s.n.], 2009. http://hdl.handle.net/11449/90899.
Анотація:
Resumo: Partindo do pressuposto de que a educação ambiental é um processo educativo que objetiva a instrumentalização dos sujeitos para o enfrentamento das verdadeiras causas da crise sócio-ambiental, visando a emancipação das condições determinadas pelo modo de produção atual, agente determinante da crise sócio-ambiental a que está submetida a humanidade, este trabalho propõe-se analisar trabalhos que foram realizados em um bairro popular, objetivando identificar e compreender as diferentes abordagens filosófico-políticas que se expressam nas ações ambientais, ao passo em que pretendemos identificar os fatores indicativos de impactos qualitativos que essas ações proporcionaram na organização do ensino escolar e na comunidade, entendendo-as como espaço educativo. Por meio da análise dos Projetos Ambientais que envolveram a temática ambiental e que foram realizados por diversos segmentos da sociedade, tais como: Universidades, Poder Público, Organizações não-governamentais e Associação de Moradores, este trabalho pretende produzir conhecimentos que contribuam para o enfrentamento da problemática ambiental, buscando o aprofundamento da reflexão de alguns de seus princípios na perspectiva da educação ambiental crítica.Abstract: Assuming that environmental education is an educational process which aims at exploitation of the subjects to facing the real causes of social and environmental crisis, to the emancipation of the determined conditions by the current mode of production, a key agent of social and environmental crisis in that the humanity is the subject, this work proposes to examine works have done in a popular district. It aims to identify and understand the different philosophical and politics approaches, those are expressed in environmental actions, while we intend to identify the qualitative impacts those actions provided in the scholl daily and in the community, understanding them as educational spaces. Through the analysis of Environmental Projects those involved the environment thematic and have been done by some segments of society, such as: Universities, Public Authorities, Nongovernmental organizations and Associations of residents. This work intends to produce knowledge to help facing the environmental problem, seeking to deep the reflection of some of its principles under the critical environmental education.
Orientador: Jandira Líria Biscalquini Talamoni
Coorientador: Marília Freitas de Campos Tozoni-Reis
Banca: Haydee Torres de Oliveira
Banca: Luciana Maria Lunardi Campos
Mestre
31
Ramos, Denise Barbosa. "Avaliação do perfil farmacocinético da administração intranasal de guanosina e seu potencial neuroprotetor em um modelo de isquemia do córtex parietal cerebral por termocoagulação em ratos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/90099.
Анотація:
A isquemia cerebral é uma das principais causas de morte no mundo, sendo decorrente de uma interrupção transitória ou permanente do fluxo sanguíneo, podendo levar à massiva morte neuronal. Um dos eventos neurotóxicos relacionados à isquemia é o aumento excessivo da concentração de glutamato extracelular, o que leva a hiperestimulação do sistema glutamatérgico (excitotoxicidade) podendo assim desencadear uma cascata de eventos intracelulares nos neurônios culminando em sua morte. Nos últimos anos, o nucleosídeo guanosina tem ganhado atenção dos pesquisadores devido ao seu potencial efeito neuroprotetor frente a insultos envolvendo excitotoxicidade. Na maioria dos experimentos in vivo no qual foram observados efeitos neuroprotetores, a guanosina foi administrada sistemicamente, apresentando considerável variabilidade na magnitude de seus efeitos entre os animais. Dado que a guanosina é uma molécula endógena, podendo ser rapidamente metabolizada via sistêmica até alcançar o cérebro, novas vias de administração devem ser exploradas a fim de maximizar seus efeitos neuroprotetores. A administração pela via intranasal tem se mostrado uma excelente alternativa visto que a boa perfusão da mucosa nasal fornece um excelente local para uma rápida absorção de drogas e transporte para o cérebro via líquido cefalorraquidiano (liquor). Neste sentido, nesta dissertação avaliamos o perfil farmacocinético da administração intranasal de guanosina e seu potencial neuroprotetor em um modelo de isquemia do córtex parietal cerebral por termocoagulação em ratos. Desta maneira, investigamos a concentração de guanosina e seus metabólitos em diferentes estruturas cerebrais, além do liquor e plasma após administração de diferentes doses, volumes de injeção e tempos após injeção intranasal de guanosina pelos métodos de CLAE e de quantificação de radioatividade. Houve diferenças significativas na concentração de purinas presentes nas estruturas analisadas (bulbo, córtex e hipocampo) além do liquor e do plasma. Observamos uma proporcionalidade entre o aumento significativo de radioatividade em relação ao aumento da concentração e do volume. Além disso, comparamos os parâmetros, acima citados, de animais que receberam administração de guanosina pela via intranasal ou intraperitoneal ou não receberam guanosina, apresentando diferenças significativas entre os grupos analisados. A indução isquêmica causou prejuízo sensoriomotor e lesão cerebral nos animais, os quais foram revertidos pelo tratamento com guanosina. Além disso, diferenças significativas na concentração das purinas foram observadas no plasma e no liquor desses animais as quais podem estar envolvidas tanto com o dano nos animais isquêmicos quanto com o efeito neuroprotetor da guanosina. Assim, este trabalho é o pioneiro mostrando a viabilidade da administração intranasal de guanosina, além de reforçar o efeito neuroprotetor da mesma frente a um modelo de isquemia.Cerebral ischemia is a major cause of death worldwide is caused by a transient or permanent interruption of blood flow and can lead to massive neuronal death. One of neurotoxic events related to ischemia is the excessive increase in the extracellular concentration of glutamate, which leads to hyperstimulation of the glutamatergic system (excitotoxicity) thus triggering a cascade of intracellular events culminating in neurons death. In recent years, the guanosine nucleoside has claimed researchers attention because of its potential neuroprotective effect against insults involving excitotoxicity. In most in vivo experiments in which guanosine presented neuroprotective effects, it was administered systemically, resulting in considerable variability in the magnitude of their effects. Since guanosine is an endogenous molecule being rapidly metabolized systemically before to reach the brain, new routes of administration should be explored in order to maximize their neuroprotective effects. The intranasal route has proven to be an excellent alternative because the good perfusion of the nasal mucosa provides a great via for a quick absorption for drug transport to the brain via cerebrospinal fluid (CSF). In this sense, this thesis evaluated the pharmacokinetic profile of intranasal administration of guanosine and its potential neuroprotective in a model of cerebral ischemia in parietal cortex by thermocoagulation in rats. Thus, we investigated the concentration of guanosine and its metabolites in different brain structures, as well as CSF and plasma after administration of different doses, injection volumes and times after intranasal injection of guanosine by HPLC methods and quantification of radioactivity. There were significant differences in the concentration of purines present in the analyzed structures (cerebral bulb, cortex and hippocampus) plus CSF and plasma. We observed proportionality between the significant increase of radioactivity in relation to the increased concentration and volume. Furthermore, we analyzed these parameters in the plasma and CSF of rats which received intranasally or intraperitoneally injection of guanosine and with those that did not receive it, showing significant differences between these groups. The ischemic induction caused sensorimotor deficit and brain injury, which were reversed by guanosine treatment. Moreover, significant differences in the concentration of purines were observed in plasma and CSF of the animals which can be related with both the ischemic damage as well as with the neuroprotective effect of guanosine. In conclusion, this work is the pioneer showing the viability of intranasal administration of guanosine, in addition to reinforcing the potential neuroprotective effect of guanosine.
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Boggs, George Lemuel IV. "Turbine Engine Thrust Measurements Using a Non-Intrusive Acoustic Technique." Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/90299.
Анотація:
Experiments were conducted to measure the thrust generated from a commercial jet engine. This thrust estimation was done using a pneumatic horn as the sound source with two arrays of microphones directly across the exhaust stream. The two arrays were separated by an axial distance downstream. Exhaust centerline measurements were taken at varying engine conditions, specifically; 30%, 50%, 60%, 70%, 80% and 100% engine power. An acoustic thrust estimation showed good agreement with measured thrust during the test campaign. In addition, a full traverse of the acoustic rig through the exhaust stream was completed for the purpose of tomography reconstruction. This reconstruction technique was able to pick up key features of the flow field.Master of Science
33
Seaman, Shane Thomas. "Material Related Effects on the Structural Thermal Optical Performance of a Thermally Tunable Narrowband Interferometric Spectral Filter." Diss., Virginia Tech, 2019. http://hdl.handle.net/10919/90799.
Анотація:
High Spectral Resolution Lidar (HSRL) is a backscatter lidar technique that employs an optical/spectral filter to distinguish between particulate (Mie) and molecular (Rayleigh) backscattered light. By separating the two types of returns, higher accuracy measurements are possible that will enable improved climate models, air quality measurements, and climate forecasting. A spaceborne HSRL instrument can provide great impact in these areas by enabling near-continuous measurements across the Earth, however the optical filter technology has typically been too complex for reliable long-duration space flight due to the need for complicated and costly electro-optic feedback loops, extra alignment detectors, and additional laser sources. Furthermore, these complexities limit the filter from use in other applications. In this research, a high-performance, ultra-narrowband interferometric optical filter with a specific thermo-optical behavior has been designed and built. The interferometer has been designed such that it can be reliably adjusted/tuned by simply monitoring and adjusting the temperature. The greatly reduced operational complexity was made possible through high-accuracy thermal characterization of the interferometer materials, combined with detailed Structural-Thermal-Optical-Performance (STOP) modeling to capture the complicated interactions between the materials. The overall design process, fabrication procedures, and characterization of the optical filter are presented.Doctor of Philosophy
LiDAR (an acronym for Light Detection and Ranging) is a technology that can be used to measure properties of the atmosphere. It is similar to radar, but uses much smaller light waves rather than larger radio waves, enabling more detailed information to be obtained. High Spectral Resolution Lidar (HSRL) is a lidar technique that uses a high precision optical filter to distinguish between light that scatters from particulates (such as dust, smoke, or fog) and light that scatters from molecules (such as oxygen, nitrogen, or carbon dioxide) in the atmosphere. By separating the two types of backscattered light, higher accuracy measurements are possible that will enable improvements in climate models, air quality measurements, and climate forecasting. A spaceborne HSRL instrument can provide great impact in these areas by enabling near-continuous measurements across the Earth; however, the optical filter technology has typically been too complex for reliable long-duration spaceflight due to the need for complicated and expensive additional hardware. In this research, a high-performance HSRL optical filter that can be reliably operated by simply monitoring and adjusting the temperature has been designed, built, and tested. The greatly-reduced operational complexity has been made possible through a new process that enables more accurate prediction of the complicated interactions between the materials of the optical filter. This process is based on a combination of high-accuracy characterization of the materials and detailed structural-thermal-optical-performance (STOP) modeling. The overall design process, fabrication procedures, and characterization of the optical filter are presented.
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Motoc, Dana. "Development of green composites based on epoxidized vegetable oils (EVOs) with hybrid reinforcements: natural and inorganic fibers." Doctoral thesis, Universitat Politècnica de València, 2017. http://hdl.handle.net/10251/90399.
Анотація:
The main aim of this work id to provide integral methods to predict and characterize the properties of composite structures based on hybrid polymers and reinforcements, that could lead to useful results from an industrial point of view. This is addressed, if possible, by theoretical predictions of the effective properties by using the available experimental data.
The first part is focused on the scientific achievements of the author that allowed a quantitative characterization of the main effective properties of several composite architectures from hybrid polymers and reinforcements, based on bio matrices, tailor-made matrices and different theoretical and simulation methods using computer software to allow good comparison. The second part defines the future research lines to continue this initial investigation.
The main objectives are clearly defined to give the reader a sound background with the appropriate concepts that are specifically discussed in the following chapters. As a main objective, this research work makes a first attempt to provide a systematic analysis and prediction of composite hybrid structures.El objetivo general del trabajo es proporcionar medios integrales para predecir y caracterizar las propiedades de las estructuras de compuestos basados en polímeros y refuerzos híbridos, principales que pueden producir resultados de utilidad práctica simultáneamente. Esto se logra comparando, siempre que sea posible, las predicciones teóricas de las propiedades efectivas con los datos experimentales disponibles. Una primera parte se ocupa de los logros científicos del autor que permitieron caracterizar cuantitativamente las principales propiedades efectivas de las arquitecturas de compuestos basados en polímeros y refuerzos híbridos, basados en matrices bio, auto-desarrollados y diferentes métodos teóricos y de simulación por ordenador utilizados para la comparación. La segunda parte identifica las orientaciones futuras para la evolución y desarrollo de la ciencia y la investigación. Los objetivos generales fueron subrayados y concisos para dar al lector una visión previa de los conceptos que serán discutidos específicamente en los siguientes capítulos. Indirectamente, apuntan hacia uno de los objetivos principales de este trabajo, a saber, proporcionar una dirección para el análisis sistemático de materiales compuestos a base de refuerzos híbridos.
L'objectiu general d'aquest treball es proporcionar els mitjos integrals per tal de predir i caracteritzar les propietats d'estructures de compòsits basats en polímers i reforçaments híbrids, que poden produir resultats amb utilitat pràctica simultàniament. Aquest objectiu s'aconsegueix comparant, sempre que és possible, les prediccions teòriques de les propietats efectives amb les dades experimentals disponibles. Una primera part es centra en els temes científics en què ha treballat l'autor que han permès caracteritzar quantitativament les principals propietats efectives de les arquitectures de compòsits basades en polímers i reforçaments híbrids, derivats de matrius bio, auto-desenvolupats i diferents mètodes teòrics i de simulació informàtica per a una correcta comparació. La segona part identifica les orientacions futures per tal d'establir l'evolució i desenvolupament de la ciència i investigació lligada a la temàtica de la tesi. Els objectius generals han sigut clarament definits per tal de donar-li al lector una visió prèvia i sòlida dels conceptes que es discuteixen en capítols venidors. Indirectament, apunten cap a un dels objectius principals d'aquest treball, a saber, proporcionar una direcció per a l'anàlisi sistemàtica de materials compòsits a base de polímers i reforçaments híbrids.
Motoc, D. (2017). Development of green composites based on epoxidized vegetable oils (EVOs) with hybrid reinforcements: natural and inorganic fibers [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/90399
TESIS
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Schlitt, James Thomas. "Applying Time-Valued Knowledge for Public Health Outbreak Response." Diss., Virginia Tech, 2019. http://hdl.handle.net/10919/90399.
Анотація:
During the early stages of any epidemic, simple interventions such as quarantine and isolation may be sufficient to halt the spread of a novel pathogen. However, should this opportunity be missed, substantially more resource-intensive, complex, and societally intrusive interventions may be required to achieve an acceptable outcome. These disparities place a differential on the value of a given unit of knowledge across the time-domains of an epidemic. Within this dissertation we explore these value-differentials via extension of the business concept of the time-value of knowledge and propose the C4 Response Model for organizing the research response to novel pathogenic outbreaks.
First, we define the C4 Response Model as a progression from an initial data-hungry collect stage, iteration between open-science-centric connect stages and machine-learning centric calibrate stages, and a final visualization-centric convey stage. Secondly we analyze the trends in knowledge-building across the stages of epidemics with regard to open and closed access article publication, referencing, and citation. Thirdly, we demonstrate a Twitter message mapping application to assess the virality of tweets as a function of their source-profile category, message category, timing, urban context, tone, and use of bots. Finally, we apply an agent-based model of influenza transmission to explore the efficacy of combined antiviral, sequestration, and vaccination interventions in mitigating an outbreak of an influenza-like-illness (ILI) within a simulated military base population.
We find that while closed access outbreak response articles use more recent citations and see higher mean citation counts, open access articles are published and referenced in significantly greater numbers and are growing in proportion. We observe that tweet viralities showed distinct heterogeneities across message and profile type pairing, that tweets dissipated rapidly across time and space, and that tweets published before high-tweet-volume time periods showed higher virality. Finally, we saw that while timely responses and strong pharmaceutical interventions showed the greatest impact in mitigating ILI transmission within a military base, even optimistic scenarios failed to prevent the majority of new cases. This body of work offers significant methodological contributions for the practice of computational epidemiology as well as a theoretical grounding for the further use of the C4 Response Model.Doctor of Philosophy
During the early stages of an outbreak of disease, simple interventions such as isolating those infected may be sufficient to prevent further cases. However, should this opportunity be missed, substantially more complex interventions such as the development of novel pharmaceuticals may be required. This results in a differential value for specific knowledge across the early, middle, and late stages of epidemic. Within this dissertation we explore these differentials via extension of the business concept of the time-value of knowledge, whereby key findings may yield greater benefits during early epidemics. We propose the C4 Response Model for organizing research regarding this time-value. First, we define the C4 Response Model as a progression from an initial knowledge collection stage, iteration between knowledge connection stages and machine learning-centric calibration stages, and a final conveyance stage. Secondly we analyze the trends in knowledge-building across the stages of epidemics with regard to open and closed access scientific article publication, referencing, and citation. Thirdly, we demonstrate a Twitter application for improving public health messaging campaigns by identifying optimal combinations of source-profile categories, message categories, timing, urban origination, tone, and use of bots. Finally, we apply an agent-based model of influenza transmission to explore the efficacy of combined antiviral, isolation, and vaccination interventions in mitigating an outbreak of an influenza-like-illness (ILI) within a simulated military base population. We find that while closed access outbreak response articles use more recent citations and see higher mean citation counts, open access articles are growing in use and are published and referenced in significantly greater numbers. We observe that tweet viralities showed distinct benefits to certain message and profile type pairings, that tweets faded rapidly across time and space, and that tweets published before high-tweet-volume time periods are retweeted more. Finally, we saw that while early responses and strong pharmaceuticals showed the greatest impact in preventing influenza transmission within military base populations, even optimistic scenarios failed to prevent the majority to new cases. This body of work offers significant methodological contributions for the practice of computational epidemiology as well as a theoretical grounding for the C4 Response Model.
36
Mussolini, Ana Flávia. "Reflexões de futuros professores de matemática sobre uma prática educativa utilizando planilhas eletrônicas /." Rio Claro : [s.n.], 2004. http://hdl.handle.net/11449/90999.
Анотація:
Orientador: Miriam Godoy PenteadoBanca: Laurizete Ferragut Passos
Banca: Telma Aparecida de Souza Gracias
Resumo: Esta pesquisa trata da Formação Inicial de Professores de Matemática, em particular sobre o uso de tecnologia informática. Sabendo da problemática existente nos cursos de graduação, como, por exemplo, a desarticulação entre teoria e prática, entre formação universitária e realidade escolar, deteve-se na seguinte questão: "Quais são as perspectivas, expectativas e dificuldades que os futuros professores apresentam quando refletem sobre uma prática educativa utilizando planilhas eletrônicas na escola básica?". A pesquisa contou com a participação de dois futuros professores de Matemática da UNESP de Rio Claro. Foram realizados três encontros de planejamento, dez encontros de intervenção em uma escola pública, e dez encontros de reflexão, que ocorreram sempre após cada intervenção. Os licenciandos tiveram a oportunidade de expor suas idéias sobre as experiências realizadas e, a partir de uma análise à luz do referencial teórico, foram extraindo temas que se referem às suas expectativas, perspectivas e dificuldades. Entre eles, a gestão da sala de aula e a transposição de conteúdo, a complexidade da sala de aula, como eles percebem os alunos, as condições de trabalho na escola, ser professor e o uso de tecnologia informática.
Abstract: This research addresses the pre-service mathematics teacher education, in particular their practice with computer. Considering the problems concerning teacher education courses - as, for instance, the disarticulation between the theory and the practice, and between the university education and the school reality - it was formulated the following research question: "What are the perspectives, expectations and difficulties that the future teachers experience when they reflect on an educational practice using spreadsheets at the basic school?" The research was developed in collaboration with two future mathematics teachers from UNESP at Rio Claro, São Paulo, Brazil. It was organized three planning meetings, ten intervention meetings in a public school, and ten reflection meeting, that always took place right after each intervention meeting. The reflection meetings were videoed and transcribed. The data were analyzed with reference to the literature. Themes were identified that could be referred to their expectation, perspectives, and difficulties. These themes included: the teaching in the classroom and the transposition of the contents; the complexity of the classroom environment; the interaction with the students; the school working conditions; being a teacher; and the use of computers.
Mestre
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MORETTI, Linda. "Analysis and modelling of innovative technologies on natural gas transportation and distribution networks." Doctoral thesis, Università degli studi di Cassino, 2022. https://hdl.handle.net/11580/90999.
Анотація:
Renewable energy sources (RESs), such as wind, solar and biomass, are the keystone of the energy policy of the EU to fulfil the target of a carbon neutral economy by 2050. However, the integration of a significant share of RESs pose significant challenges to the EU energy systems as it requires, on the one hand, storing large energy volumes to match intermittent renewable supply with the pattern of energy consumption and, on the other hand, transporting renewable energy from where it can be most efficiently and feasibly produced to where it is consumed.
To overcome such challenges, it will be effective to consider the reuse of the existing natural gas (NG) infrastructure. The latter will play a crucial role in the development of a decarbonized energy system based on a large usage of RESs due to its widespread presence and its capacity to provide a cost-effective option for transporting and storing large amounts of energy for long-term period exploiting the NG transportation and distribution networks, as well as the storage complexes of the existing NG infrastructure.
This thesis aims to address, with a multi-thematic approach, the issue of innovative uses of, as well as the development of innovative technologies on, NG transport and distribution networks. To this aim, a number of five case studies were investigated to: i) evaluate the fault management strategies for NG distribution networks to minimize the disservice and to define possible structural improvement measures; ii) assess the technical feasibility of the Power to Gas concept to store intermittent RESs; iii) analyse the impact of hydrogen injection on NG networks; iv) evaluate the effectiveness of the equilibrium gasification models as a modelling tool for the design and optimization of biomass gasification systems integrated into polygenerative plants coupled with energy networks.
Results of this thesis provide useful insights to researchers, designers and policy makers, filling some of the gaps highlighted in the existing scientific literature in all the analysed areas.
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NASELLI, Flores. "NUTRIGENOMICS EFFECTS OF PHYTOCHEMICAL INDICAXANTHIN IN in vitro CELL SYSTEMS." Doctoral thesis, Università degli Studi di Palermo, 2014. http://hdl.handle.net/10447/90899.
Анотація:
Nutrition plays a key role in many aspects of health, indeed epidemiological studies
provide evidence that diet can play essential roles in reducing the risk of chronic diseases.
Accumulating evidence indicates that dietary compounds (phytochemicals) from fruit and
vegetables can modulate multiple cancer-inflammation pathways which are relevant for
chemoprevention and are commonly deregulated by epigenetic mechanisms in cancer cells,
including drug detoxification, cell cycle regulation, apoptosis induction. Epigenetic refers to
heritable alterations in gene expression that do not involve modification of the underlying
genetic DNA sequence. Although epigenetic changes are heritable in somatic cells, these
modifications are also potentially reversible, which makes them attractive and promising
avenues for tailoring cancer preventive and therapeutic strategies.
The aim of this study was to investigate the antiproliferative potential of a Cactus pear
pigment extract (Indicaxanthin) to assess the phenotypic effects on colorectal cancer cell lines
and to investigate the biological function and/or epigenetic mechanisms for Indicaxanthin’s
activity.
The antiproliferative effects of Indicaxanthin (Ind), were investigated on a number of
human cancer cell lines including hepatocarcinoma cells (HepG2, Ha22T, HUH 7), breast
cancer cells (MCF7), cervix epithelial carcinoma (HeLa) and colorectal carcinoma cells
(Caco2, LOVO1, DLD1, HT29, HCT116). Ind caused a clear dose-dependent decrease in the
proliferation of Caco2, with minor effect on the other cell lines. Flow cytometric analysis
showed a pro-apoptotic effect of the pigment at 48h in Caco2 cells. Incubation of proliferating
Caco2 cells with Ind (10μl to 100μl ) remarkably reduced the global DNA 5-methyl cytosine
methylation and caused a stable demethylation of the tumor suppressor p16INK4a gene
promoter, with reactivation of the silenced mRNA expression and accumulation of p16INK4a
protein. A decrease of the hyperphosphorylated retinoblastoma protein in favour of its
hypophospohrylated status was observed, with unaltered level of the cycline-dependent kinase
CDK4. Analysis of cell distribution in the cell cycle phases after Ind treatment showed arrest
of Caco2 cells in the S- G2/M- phase.
The effect of Ind on LINE-1 methylation levels in the other colorectal cancer cell lines
was therefore explored as well as the effect of Ind on promoter methylation status of other
genes implicated in colon carcinogenesis. Ind is able to alter the methylation status on global
and specific gene level. To rationalize the mechanism of DNA methylation changes induced
by Ind, the effect of the phytochemical on the activity and the level of DNA methyltransferase
(DNMT) was evaluated. Ind induced a dose-dependent inhibition of DNMT activity on Caco2
cells, while did not affect DNMT1 and DNMT3b level. However a significant increment of
DNMT3a was evident in Caco2 cell line. Aberrant expression of DNMTs and their isoforms
has been found in many types of cancer and their contribution to aberrant DNA methylation
has been proposed. Following this hypothesis, the effect of Ind on the expression of DNMT
splice variant, was investigated. The expression of DNMT increased appreciably only in some
cell lines with respect to only some DNMT genes after Ind treatment. DNA demethylation
may take place as an active mechanism by the activity of specific enzymes. In order to assess
whether Ind is able to induce an alteration in DNA demethylase expression, which may
explain the effects of Ind on DNA methylation in the tested cell lines, the effect of Ind on the
DNA demethylase expression was investigated. Ind induced an increased expression of some
enzymes with demethylating activity (TET2, MBD4) relatively only in some cell lines.
In this work it appears that the phytochemical Indicaxanthin induces different effects
(both epigenetic and biochemical) on colorectal cancer cell lines tested (reduction of
proliferation, induction of apoptosis, induction of cell cycle arrest, change in DNA
methylation, alteration of gene expression). The effects brought by Ind, are often variable
depending on the cell line used, such phenomenon can be attributed to the cell lines
themselves. Furthermore from in silico molecular imaging tests, in this study it was supposed
that epigenetic effects of Ind are not mediated by a direct alteration of DNMT expression,
rather by an influence of Ind on their activities. Then, Ind binding the DNMT and altering
their methyltransferase function could cause an imbalance of global DNA methylation.
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Romo, del Amo Susana. "Estudi teòric de propietats espectroscòpiques i electroquímiques de polixometalats amb metalls de transició dels grups 6-9." Doctoral thesis, Universitat Rovira i Virgili, 2009. http://hdl.handle.net/10803/9099.
Анотація:
En el primer capítol conté una introducció general de la tesis on es presenten les estructures més típiques dels polioxometal·lats i les característiques generals d'aquests complexes. En el segon capítol es presenten les metodologies computacionals en que es basen els estudis realitzats i la teoria en que es fonamenten les metodologies emprades. En el primer de resultats (capítol 3) es presenta un estudi previ on es comparen diferents mètodes computacionals amb les estructures més petites que existeixen com a POMs, els anions de Lindqvist, M6O19n-. En el segon capítol de resultats (capítol 4), s'ha reproduït l'espectre electrònic de polioxometal·lats que contenen un metall paramagnètic en estructures d'Anderson, XM6O24, utilitzant varies metodologies computacionals. En el cinquè capítol s'ha realitzat l'estudi semiquantitatiu de les propietats electroquímiques que experimenten les estructures "sandwich" amb més d'un metall paramagnètic en la seva estructura, en els que la reducció es produeix de manera selectiva. S'ha verificat la posició on es produirà la primera reducció de l'anió, així com l'estat fonamental de les espècies oxidades i reduïdes. S'ha pogut reproduir amb relativa exactitud l'electroquímica que presenten aquests anions i l'efecte del pH en els processos de reducció. El sisè capítol, és el més extens, s'han estudiat exhaustivament la modificació de les propietats d'un POM quan aquest conté un àtom de Tc. Primer es fa una discussió exhaustiva de les estructures de Lindqvist, M6O19n-, que s'agafa com a model per a posteriorment ser ampliat amb les estructures de Wells-Dawson. Aquests últims són uns candidats ideals per a la immobilització de l'ió Tc (99Tc) que s'obté com a residu radioactiu en les centrals nuclears. A continuació, s'ha ampliat l'estudi amb metalls de transició dels grup 6-9 on s'ha observat una tendència general en les propietats redox i de la basicitat que produeixen les substitucions dels metalls. En el capítol setè, després de veure com es modifiquen les propietats redox dels POMs monosubstituïts amb metalls de transició dels grups 6-9, s'ha passat a estudiar electrònicament i electroquímicament els anions de Keggin monosubstituïts, {MN}W11O39n- i s'han comparat amb els corresponents complexes oxo, {MO}W11O39 n-. En l'últim capítol es presenten les conclusions extretes dels treballs realitzats al llarg d'aquesta tesis.The doctoral thesis consists of eight chapters. The first chapter contains an overview of the theories on the structures are more typical of polioxometalat and the general characteristics of these complexes. The second chapter presents the computational methods that are based on extensive research and theory that is based on the methodologies used. The first results (Chapter 3) iare presented on a previous study comparing different computational methods with the smallest structures that exist as polyoxoanions, the Lindqvist anions, M6O19n-. The second results chapter (Chapter 4), has reproduced the spectrum of electronic polioxometalat containing a paramagnetic metal in Anderson structures, XM6O24, using various computational methods. In the fifth chapter is the study conducted semiquantitative electrochemical properties of the sandwich type polyoxometalats with more than a paramagnetic metal in its structure, in which the reduction occurs selectively. Verified the position where the first reduction in this anion, as well as the fundamental species of oxidized and reduced. Could play with relative accuracy the electrochemical presented and how these anions in the pH of the reduction process. The sixth chapter is the largest, have been studied extensively the properties of a POM when it contains an atom of Tc. First is a comprehensive discussion of the structures Lindqvist, M6O19, which is taken as a model to be expanded later with the structures of Wells-Dawson. These are ideal candidates for the immobilization of ion Tc (99Tc) that occurs as a radioactive waste at nuclear power plants. Then, the study has been extended to transition metal of groups 6-9 where there has been a general trend in the redox properties and the basicity that produce the substituted metal. After seeing how altering the redox properties of metal knobs monosubstituted transition from groups 6-9, have gone to study the electronic and electrochemical of Keggin anions, {MN}W11O39n- and we have compared with the corresponding oxo complex, {MO}W11O39n-. In the final chapter presents the conclusions drawn from work done throughout this thesis.
40
Stanley, Andrew. "State estimation of in-flight aircraft centre of gravity." Thesis, Loughborough University, 2011. https://dspace.lboro.ac.uk/2134/9099.
Анотація:
For all types of aircraft (civil, military, manned, unmanned) the aircraft designer specifies a safe range for the centre of gravity (cg) of the aircraft and designs the aircraft to operate safely within these limits. Changes to the cg may affect aircraft stability, performance and fuel economy so it is an important system parameter. Changes to the in-flight cg position have traditionally been estimated by calculating fuel burn and from that calculating the change in weight and hence change in cg. Other techniques to estimate in-flight aircraft cg are included in the literature review. The motivation for additional cg estimation techniques arise from the potential benefits they offer to a Flight Control System (FCS). These benefits include the potential for improved fault detection and an improved FCS design with better aircraft performance and fuel economy. State estimation using Kalman filters has been used since the 1960 s in many fields of application including the aerospace industry. This thesis will introduce the concept of using state estimation to detect the unexpected angular acceleration associated with a cg change. This state estimation concept is applied to a linear Phantom aircraft model and then to a complex non-linear aircraft model of a delta-canard military aircraft, called ADMIRE. The most common state estimation approach used with non-linear systems is the Extended Kalman Filter (EKF), but an alternative approach is proposed in which the pitching and roll moment coefficient derivatives are selectively modified based upon the aircraft angle of attack, speed and altitude. Both longitudinal and lateral cg estimators are described and examples of their performance are provided and compared with an EKF version of the estimator. A discrete version of the estimator is also described and used with a hardware fuel rig. Faults are applied to the fuel rig and it is proposed that the estimator could aid the fault diagnosis. In a real implementation the aircraft will not be precisely modelled, therefore a sequence of robustness tests are included to identify the critical aircraft parameters affecting the estimator. The results show that a cg estimator based upon a Kalman filter, and using a selective coefficient correction approach, can satisfy the performance requirements specified by the industrial sponsor, BAE Systems.
41
Rozier, Joseph Michael 1977. "Here&There : an augmented reality system of linked audio." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/9099.
Анотація:
Thesis (S.B. and M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2000.Includes bibliographical references (leaves 49-50).
In this thesis, I designed a system for augmenting a space with linked audio. Using this system, individuals can associate audio clips with a location in real-world space. When an individual using the system passes through this augmented space, he or she can hear the audio clips that have been left by traveling through the associated locations. Furthermore, audio clips in the environment can be linked together, so that an individual listening to one audio clip can be directed to related audio clips in the augmented space. In addition, a method of allowing the user to navigate through the augmented space is presented.
by Joseph Michale Rozier.
S.B.and M.Eng.
42
Rivera, Sotelo Giovanna Teresa. "Factores que influyen en la adherencia al tratamiento en adultos mayores diabéticos que acuden al área de emergencia del Hospital Nacional de la PNP “Luis N. Sáenz”." Doctoral thesis, Universidad Nacional Mayor de San Marcos, 2017. https://hdl.handle.net/20.500.12672/9099.
Анотація:
Determina los factores que influyen en la adherencia al tratamiento en pacientes adultos mayores diabéticos tipo 2 que acuden al área de emergencia del Hospital Nacional PNP “Luis N. Sáenz” en el periodo enero – marzo 2016. Realiza una investigación no experimental, descriptivo - correlacional, trasversal, prospectivo. Se estudiaron a 95 adultos mayores diabéticos, se recogieron los datos demográficos, se aplicó el test de Morisky-Green-Levin para valorar la adherencia al tratamiento y el test de APGAR Familiar para evaluar la percepción de funcionalidad de la familia. De los 95 pacientes, 49 fueron varones y 46 mujeres, la mayoría con edades de entre 60 a 69 años, la ocupación más frecuente fue policía titular, los niveles de glicemia más común fueron de 201 a 400 mg/dL, el tipo de esquema de tratamiento más común fue la metformina y la mayoría de los adultos presentaron alguna comorbilidad (con mayor frecuente hipertensión arterial), el 40% presentaron disfunción familiar leve y el 15.8% presentaron adherencia terapéutica. La dieta como esquema terapéutico (p=0.006), la presencia de percepción de disfunción familiar (p=0.005) y sus aspectos participación (p=0.013), ganancia (p=0.033) y afecto (p=0.002) influyeron en la adherencia al tratamiento en pacientes adultos mayores diabéticos tipo 2. Concluye que la dieta como esquema terapéutico y la presencia de percepción de disfunción familiar son factores que influyen en la adherencia al tratamiento en pacientes adultos mayores diabéticos tipo 2 que acuden al área de emergencia del Hospital Nacional PNP “Luis N. Sáenz”.Tesis
43
Morling, Frances. "Cape Town's cats: reassessing predation through kitty-cams." Master's thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/9099.
Анотація:
Includes bibliographical references.Domestic cats (Felis catus) are abundant generalist predators that exploit a wide range of prey within and adjacent to the urban matrix. Cats are known to have contributed to the extinction and endangerment (mostly on islands) of a number of indigenous species, including birds, small mammals, reptiles and amphibians. Most research on this important topic has been carried out in the developed world, predominantly in Australia, New Zealand, the U.K., the U.S. and Canada with only four studies carried out in Africa. Of these, two studies in Cape Town suggest that domestic cats have a big impact on wildlife but these studies may have underestimated predation because they failed to account for the proportion of prey not returned to participants’ homes. In this study I used kitty-cams in an attempt to provide a prey correction factor for urban cats in Cape Town, South Africa. I investigated hunting of wildlife by free-ranging domestic cats in Newlands, a suburb of Cape Town, South Africa over 5 weeks in 2013. I monitored 13 cats (6 deep-urban and 7 urban-edge) by questionnaire survey, asking cat owners to record all prey items returned by their cats. A total of 43 prey items were returned, 42% of which were small mammals, 30% invertebrates, 12% reptiles, 9% amphibians and 7% birds. Combining these data with two similar survey studies carried out in Cape Town I estimated that a total of 118 cats caught an average of 0.04 prey items per cat per day. Ten of the 13 cats were also monitored for 3 weeks using kitty-cam video cameras. Participating cats wore a video camera and all activity was analysed for prey captures and behavioural activity patterns.
44
Oh, Subin. "The effect of dynamic written corrective feedback for learners of Korean." BYU ScholarsArchive, 2020. https://scholarsarchive.byu.edu/etd/9099.
Анотація:
This study investigates the effectiveness of dynamic written corrective feedback (DWCF) for intermediate learners of Korean as a foreign language (KFL) compared to traditional types of written corrective feedback. DWCF is an innovative method of providing written corrective feedback on students' writing that has primarily been used in English as a second language (ESL) settings. It aims to improve learners' linguistic accuracy and requires multilayered interaction between teachers and students. Although DWCF has been effectively used to increase linguistic accuracy in various ESL settings, it has not yet been widely applied to other language learning settings. This study demonstrates the extent to which DWCF increases the linguistic accuracy of intermediate KFL learners and determines DWCF's impact on fluency and complexity. The treatment group (n = 9) was managed with DWCF and the control group (n = 10) wrote six essays over a 12-week period. The pre- and post-test results were analyzed to determine differences in linguistic accuracy, fluency, and complexity between the two groups. A mixed-model repeated measures ANOVA revealed that the treatment group's accuracy significantly increased compared to the control group, whereas there was no significant difference in fluency or complexity for either group. Limitations and suggestions for future research are discussed in the conclusion.
45
Kroeker, Rosalie. "Rhythmic behaviors in typically developing infants, and infants with later diagnosed autism or developmental delay /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/9099.
46
Delgado, Robert. "Density properties of Euler characteristic -2 surface group, PSL(2,R) character varieties." College Park, Md.: University of Maryland, 2009. http://hdl.handle.net/1903/9099.
Анотація:
Thesis (Ph. D.) -- University of Maryland, College Park, 2009.Thesis research directed by: Dept. of Mathematics. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
47
Mochila, Miguel Filipe Pateiro. "O nada, o desejo e o excesso: literatura e humanismo em Miguel de Unamuno e Vergílio Ferreira." Master's thesis, Universidade de Évora, 2013. http://hdl.handle.net/10174/9099.
Анотація:
Observando os pontos de contacto entre as poéticas de Miguel de Unamuno e
Vergílio Ferreira, consideraremos a pertinência da definição de ironia trágica para a
delimitação da problemática ficcional e existencial de ambos os autores, segundo a qual
o Homem pressente a patética discordância entre o real em que se move e o ideal que
projeta nas diversas experiências do mundo.
As problemáticas artística e amorosa constituem, nessa moeda irónica, uma
poética da esperança na revelação do encontro do Homem consigo mesmo, do seu
caminhar da face real à face ideal que o mobiliza. Partindo do tanatológico como
questionamento fundador, as obras de ambos os autores descobrem possibilidades
aparentemente salvíficas, através daquilo a que chamamos a sensualização da
experiência redentora e a apologia do homem sensível.
Perante o absurdo da nadificação do ego, ambos os autores propõem uma
reversão ética da problemática antropológica, em defesa de uma heroicização da
existência; ### Title
Nothingness, desire and excess: literature and humanism in Miguel de Unamuno
and Vergílio Ferreira
Abstract
Focusing on similar traits between the poetics of Miguel de Unamuno and
Vergílio Ferreira, we shall consider the appropriateness of the definition of tragic irony
regarding the depiction of the fictional and existential problematic in both authors,
according to which man senses a pathetic discrepancy between the real through which
he moves and the ideal that he projects in different mundane experiences.
The artistic and amorous issues constitute, in that ironic currency, a poetic of
hope in the revealing encounter of man with himself, in his shift from the real bearing
towards the ideal bearing that mobilizes him. Deriving from the thanatological as a
founding question, the works of both authors discover possibilities of apparent salvation
through what we call the sensualization of redemptive experience and the apology of the
sensitive man.
Facing the absurdity of the nihilation of ego, both authors propose an ethic
inversion of the anthropological problematic, in defense of a heroism of existence.
48
Bortot, Lodovica <1991>. "Il Cyber-riciclaggio ed i paradisi fiscali: le nuove dinamiche nel processo di money laundering." Master's Degree Thesis, Università Ca' Foscari Venezia, 2016. http://hdl.handle.net/10579/9099.
Анотація:
La Tesi di laurea propone un’analisi del riciclaggio di denaro quale fenomeno in continua evoluzione ed influenzato dalle diverse dinamiche economiche, giuridiche e sociali.
La lotta e il contrasto al riciclaggio di denaro sono resi di difficile realizzazione a causa di due aspetti fondamentali. Il primo aspetto riguarda la normativa internazionale che si presenta di difficile interpretazione e di complessa attuazione. Il secondo aspetto riguarda la natura del fenomeno del riciclaggio: la sua continua evoluzione e mutevolezza, insieme all’esistenza di sistemi finanziari sempre più globali, interdipendenti e complessi, rende difficile le attività di contrasto al riciclaggio date le numerose possibilità di cambiamento, sviluppo ed internazionalizzazione proprie di questo fenomeno.
L’analisi svolta sul fenomeno del riciclaggio, sugli attori coinvolti e sulla normativa di contrasto dimostra come i paradisi fiscali, gli offshore websites e le monete virtuali siano i principali canali utilizzati dagli attori coinvolti nel riciclaggio di denaro.
I paradisi fiscali, sia per ragioni politico-economiche sia geografiche, rimangono oggi, nonostante la normativa a livello internazionale sul antiriciclaggio, una delle principali mete utilizzate dalle organizzazioni criminali e dagli intermediari per riciclare il denaro “sporco”. In particolare, sono approfondite le caratteristiche che rendono i paradisi fiscali un territorio così fertile per riciclare il denaro.
In seguito, vengono analizzate le nuove frontiere e le moderne dinamiche del riciclaggio di denaro rappresentate dal fenomeno del cyber-riciclaggio. Il cyber-riciclaggio e più in generale il cyber-crime sono sistemi moderni utilizzati dalla criminalità organizzata per infiltrarsi nel sistema economico. La rete internet si rivela quale mezzo di facilitazione delle fasi di riciclaggio grazie alla capacità nell’agevolare le operazioni attraverso le quali si compiono tali criminose.
Le nuove monete virtuali come il “Bitcoin”, gli offshore websites ed i servizi bancari online sono nuovi strumenti fondamentali del processo di cyber-laundering.
Il lavoro di tesi si conclude con un’analisi sulle nuove dinamiche e sulla spersonalizzazione dovuta al cyber-riciclaggio ed, in particolare, come questi aspetti siano utilizzati quali strumenti per raggiungere i paradisi fiscali attraverso conti e società intestate a terze persone.
49
Bandeira, Carina Barbosa. "Prevalência de depressão em idosos institucionalizados." Universidade de Fortaleza, 2012. http://dspace.unifor.br/handle/tede/90199.
Анотація:
Made available in DSpace on 2019-03-29T23:43:53Z (GMT). No. of bitstreams: 0
Previous issue date: 2012-12-19Introduction: In the aging population, depression is among the most frequent chronic diseases. Affect the functionality of the elderly and is considered a serious public health problem. It is a fact that depressive symptoms show up in greater numbers in the institutionalized elderly than in the community due to changes related to family disengagement and adaptation to new customs. Objective: To identify the prevalence of depression in elderly residents in large government and non-government long-stay institutions for the elderly (LTCF) in the city of Fortaleza. Methodology: Quantitative research, cross, drawn through a semi-structured questionnaire. Discusses data sociodemographic, clinical and diagnostic criteria of DSM-IV - TR. The research consisted of all elderly residents in two large nursing homes in Fortaleza. Data were statistically analyzed using SPSS version 20.0 Software. Results: In both institutions prevailed: women, unmarried, illiterate, aged between 70 and 79 years. Of the 237 patients evaluated, 82 (34.6%) had major depression. In the diagnosis of major depression by LTCF, statistical significance was detected when applying the inference test, chi-square, among elderly patients with this pathology in both LTCF (25.6% versus 39% in LTCF governmental and non-governmental respectively) (p = 0.042). Statistical significance was observed between the subject and type of nursing home institutionalization, 24 elderly (29.3%) were institutionalized willingly in LTCF nongovernmental, while 9 (11%) reached the governmental ILPI abandoned by their families (p = 0.001). On family visits, 40 (48.8%) received them in LTCF nongovernmental, while only 9 (6.1%) of depressed elderly had contact with their relatives in government LTCF (p = 0.002). Conclusion: It is considered high the prevalence rate of major depression found in the elderly research, resembling what other studies have found about depressive symptoms in institutionalized elderly. The elderly in the nongovernmental LTCF have become more vulnerable to depression, which is necessary to carry out more in-depth study. The DSM-IV-TR was effective as screening tools for depressive symptoms, however it is important to compare it with the geriatric depression scale of Yesavage, being easy to use and widely used in our environment.
Introdução: Na população envelhecida, a depressão encontra-se entre as doenças crônicas mais frequentes. Prejudica a funcionalidade do idoso e é considerada como um problema grave de saúde pública. É fato que sintomas depressivos se apresentam em maior número nos idosos institucionalizados do que na comunidade, em consequência das mudanças relacionadas à desvinculação familiar e adaptação a novos costumes. Objetivo: Identificar a prevalência de depressão em residentes em instituições de longa permanência de idosos (ILPI) de grande porte governamental e não governamental no Município de Fortaleza. Metodologia: Pesquisa quantitativa, transversal, elaborada por meio de um questionário semiestruturado. Aborda dados sociodemográficos, clínicos e os critérios de diagnóstico do DSM-IV - TR. O universo da pesquisa constituiu-se de todos os idosos residentes nas duas ILPI de grande porte do Município de Fortaleza. Os dados foram analisados estatisticamente, por meio do software SPSS versão 20.0 (SPSS Inc, Chicago, IL, USA). Resultado:. Em ambas as instituições prevaleceram: mulheres, solteiros, não alfabetizados, faixa etária entre 70 e 79 anos. Dos 237 pacientes avaliados, 82 (34,6%) apresentaram depressão maior. No diagnóstico de depressão maior por ILPI, detectou-se significância estatística, ao se aplicar o teste de inferência, quiquadrado, entre os idosos acometidos por esta patologia (25,6% versus 39% nas ILPI governamental e não governamental respectivamente) (p=0,042); entre motivo da institucionalização e tipo de ILPI, 24 idosos (29,3%) institucionalizaram-se por vontade própria na ILPI não governamental, enquanto 9 (11%) chegaram à ILPI governamental abandonados por suas famílias (p=0,001). Relativamente à visita de familiares, 40 (48,8%) recebiam-nas na ILPI não governamental, enquanto apenas 9 (6,1%) dos idosos deprimidos tinham contato com seus parentes na ILPI governamental (p=0,002). Conclusão: Considera-se alta a taxa de prevalência de depressão maior detectada nos idosos da pesquisa, assemelhando-se à de outros estudos que constataram sintomas depressivos em idosos institucionalizados. Os idosos da ILPI não governamental mostram-se mais fragilizados à depressão, fazendo-se necessário realizar estudos mais aprofundados. O DSM-IV- TR mostrou-se eficaz como instrumento de rastreio de sintomas depressivos, contudo seria importante compará-lo com a escala de depressão geriátrica de Yesavage, por ser de fácil aplicação e bastante utilizada em meio local.
50
Betanin, Tatiana. "TRANSCENDÊNCIA E JOGO NA ONTOLOGIA FUNDAMENTAL DE MARTIN HEIDEGGER." Universidade Federal de Santa Maria, 2004. http://repositorio.ufsm.br/handle/1/9099.
Анотація:
This dissertation deals with a new matter that appears in one of Martin Heidegger recently published courses Gesamtausgabe, which is the winter 1928/29 lesson named Introduction to Philosophy. In this sense, our objective consists in analysing and rebuilding the game concept presented as a way to transcendence conceptual determination. This concept does not just relate to transcendence but also to the comprehension of being that is considered a transcendence essencial moment. Then, besides the game and transcendence notion, it will be carachterized the comprehension of being notion. As a result, we have the evidence that transcendence is the condition to the comprehension of being possibility. In addition, transcendence is the senses of being formation and these senses either can be manifested or can be historically concealed.Esta dissertação trata de uma problemática nova que aparece em um dos cursos recentemente publicado na Gesamtausgabe de Martin Heidegger, que é a lição de inverno de 1928/29 intitulada Introdução à Filosofia . O nosso objetivo consiste em analisar e reconstruir o conceito de jogo que se apresenta como a forma de determinação conceitual da transcendência. Esse conceito não apenas se relaciona à transcendência, senão também à compreensão de ser, que é considerada um momento essencial da transcendência. Então, além da noção de jogo e de transcendência, será caracterizada a noção de compreensão de ser. Como resultado temos a constatação de que a transcendência é a condição de possibilidade da compreensão de ser. Além disso, ela é a formação de sentidos de ser, sentidos que tanto se manifestam como se ocultam historicamente.