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Бєлих, Віталій Ростиславович. "Конструкторсько-технологічне забезпечення електричної платформи "odi" для людей з інвалідністю (комплексна магістерська дисертація)". Master's thesis, КПІ ім. Ігоря Сікорського, 2019. https://ela.kpi.ua/handle/123456789/31365.
Повний текст джерелаBased on the analysis of the state of the issue in the field of transportation of people with disabilities, it is determined that in developed countries there are developments that can improve transportation conditions, including those equipped with electric movement drives. Such technologies are already available in most countries to a wide range of people with medium and high incomes.In the process, a vehicle design was created, the rear suspension system of the electric platform was analyzed and designed. To verify the results, a computer simulation of the suspension was carried out.Made in a 1: 4 scale layout of the rear suspension truss, and the layout design of the electric platform.
Bowd, Rebecca Elizabeth. "The purposes of reading in late Georgian Britain : science, medicine, industry and intellectual culture in the Leeds subscription libraries, 1768-1815." Thesis, University of Leeds, 2015. http://etheses.whiterose.ac.uk/11145/.
Повний текст джерелаGauld, Craig. "The fantasy of the corroborative and transformative archive : the authority of archival beginnings." Thesis, University of Glasgow, 2010. http://theses.gla.ac.uk/1511/.
Повний текст джерелаFuchs, Thomas. "Bibliotheca Ilfeldensis: Die Bibliothek der ehemaligen Klosterschule Ilfeld." MVB, 2008. https://ul.qucosa.de/id/qucosa%3A71579.
Повний текст джерелаNale, Janet Yakubu. "Isolation and characterisation of temperate bacteriophages of the hypervirulent Clostridium difficile 027 strains." Thesis, University of Leicester, 2013. http://hdl.handle.net/2381/27918.
Повний текст джерелаSchneider, Ulrich Johannes. "Sammlungen, die Bibliothek, die Zukunft." Leipziger Universitätsverlag, 2012. https://ul.qucosa.de/id/qucosa%3A13034.
Повний текст джерелаSchneider, Ulrich Johannes. "Universitätsbibliothek Leipzig." Leipziger Universitätsverlag, 2009. https://ul.qucosa.de/id/qucosa%3A13032.
Повний текст джерелаMatook, Khaled Soliman. "The academic libraries of the future in Saudi Arabia and their manpower requirements." Thesis, Manchester Metropolitan University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270886.
Повний текст джерелаCalixto, José António. "The educational roles of public libraries in Portugal : political and professional perceptions." Thesis, University of Sheffield, 2003. http://etheses.whiterose.ac.uk/14613/.
Повний текст джерелаKlai, Amira. "Clostridium difficile : étude du processus de colonisation et d'hypervirulence de la souche épidémique 027." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00922985.
Повний текст джерелаBarketi-Klai, Amira. "Clostridium difficile : étude du processus de colonisation et d’hypervirulence de la souche épidémique 027." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA114844/document.
Повний текст джерелаClostridium difficile is an enteropathogenic bacterium that causes post-antibiotic nosocomial diarrhea and pseudomembranous colitis. During the last decade, the incidence and the severity of C. difficile infections have significantly increased in America and Europe. This evolution seems to be related to the emergence and to the rapid dissemination of a particularly virulent clone of PCR-ribotype 027. The main virulence factors of C. difficile are the TcdA and TcdB cytotoxins which are responsible for intestinal lesions. However, the intestinal colonization by the bacterium is considered as an indispensible step for infection.To better understand the hypervirulence mechanisms of strain 027, we focused on the study of intestinal colonization process of this strain compared to the colonization process of the non-epidemic strain 630Δerm. First, we studied the role of the fibronectin binding protein FbpA. In vitro and in vivo characterization of a mutant FbpA showed the involvement of this protein in the colonization process of the non-epidemic strain 630Δerm. The difficulty of obtaining a mutant in the epidemic strain R20291 027 does not allow us to compare the adhesive properties of FbpA between the two strains.In a second step, we studied the characteristics of flagellar proteins FliC, FliD, FlgE and MotB. We showed that the flagella have a role in the adhesion and colonization of strain 027 and that this role is less important in strain 630Δerm. We also showed that flagella are involved in other cellular processes than adhesion and colonization. A transcriptomic study of a FliC mutant in 027 R20291 shows that flagellin is also involved in toxin production, sporulation and in the adaptation of bacteria to stress conditions. Further study should be performed to better understand the regulation system that governs these different cellular processes. Finally, we performed a transcriptomic analysis of the kinetic of in vivo colonization of the 027 R20291 strain. The study revealed a very early expression of toxin and sporulation genes during the first stages of the infection process. This analysis also allowed us to identify some genes, specific to 027 strains, which appeared regulated during the infection process. These genes could be involved in the virulence of C. difficile 027 strains and could provide new issues of study to better understand C. difficile virulence
Scholl, Heike. "Leseförderung in den Schulferien." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-39072.
Повний текст джерелаSteglich, Matthias [Verfasser], and Ulrich [Akademischer Betreuer] Nübel. "Evolutionsgenetik und Phylogeographie von Clostridium difficile Ribotyp 027 in Deutschland / Matthias Steglich ; Betreuer: Ulrich Nübel." Braunschweig : Technische Universität Braunschweig, 2017. http://d-nb.info/1175890553/34.
Повний текст джерелаMartin, Melissa Jane. "Characterisation of the `agr' locus and naturally occurring membrane vessicles in `Clostridium difficile' 027 strains." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590512.
Повний текст джерелаJohansson, Charlotta. "Safety and mobility of children crossing streets as pedestrians and bicyclists." Doctoral thesis, Luleå, 2004. http://epubl.luth.se/1402-1544/2004/027.
Повний текст джерелаAl-Mahri, Bakhit Ahmed Rajhit. "An evaluation of the effectiveness of the learning resource centres in the colleges of education in Oman." Thesis, University of Glasgow, 2003. http://theses.gla.ac.uk/4847/.
Повний текст джерелаSekulovic, Ognjen. "Étude de l'impact des prophages sur la biologie de Clostridium difficile." Mémoire, Université de Sherbrooke, 2010. http://savoirs.usherbrooke.ca/handle/11143/4049.
Повний текст джерелаSchneider, Ulrich Johannes. "Sammlungen, die Bibliothek, die Zukunft." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-157024.
Повний текст джерелаSirard, Stéphanie. "Analyse génotypique et phénotypique d'isolats cliniques de Clostridium difficile et comparaison en fonction de la sévérité des symptômes." Mémoire, Université de Sherbrooke, 2011. http://hdl.handle.net/11143/5547.
Повний текст джерелаSwirtun, Linda R. "Anterior cruciate ligament injury : factors affecting selection of treatment and intermediate outcome /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7357-027-3/.
Повний текст джерелаWerme, Martin. "On natural and drug-induced reward : genetic, biochemical and behavioral comparisons /." Stockholm : [Karolinska Univ. Press], 2001. http://diss.kib.ki.se/2001/91-7349-027-X/.
Повний текст джерелаTang, Lisa Eng. "Age-associated hepatic drug transporter expression and its implications for pediatric pharmacotherapy." View the abstract Download the full-text PDF version, 2007. http://etd.utmem.edu/ABSTRACTS/2007-027-Tang-Index.html.
Повний текст джерелаTitle from title page screen (viewed on June 19, 2008). Research advisor: Bernd Meibohm, Ph.D. Document formatted into pages (xiv, 100 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 96-100).
Nooh, Mohammed Mostafa. "Biochemical and immunological mechanisms underlying differential interaction of superantigens with host immunogenetic factors in streptococcal sepsis." View the abstract Download the full-text PDF version, 2008. http://etd.utmem.edu/ABSTRACTS/2008-027-Nooh-index.html.
Повний текст джерелаTitle from title page screen (viewed on Sept. 17 2008). Research advisor: Malak Y. Kotb, Ph.D. Document formatted into pages (xvii, 189 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 161-189).
Robinson, Bridget K. "Determinants of physical activity behavior and self-efficacy for exercise among African American women." View the abstract Download the full-text PDF version, 2009. http://etd.utmem.edu/ABSTRACTS/2009-027-Robinson-index.htm.
Повний текст джерелаTitle from title page screen (viewed on September 18, 2009). Research advisor: Mona N. Wicks, Ph.D. Document formatted into pages (x, 85 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 63-71).
Capitanio, Lara. "Foglio 027 Bolzano. Studio petrografico delle vulcaniti permiane del settore Val di Tires – Passo Nigra, Alta Val d’Ega, Bolzano." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/14458/.
Повний текст джерелаGemein, Stefanie [Verfasser]. "Etablierung eines Testverfahrens zur Prüfung sporizider Flächendesinfektionsmittel: mit dem Schwerpunkt Clostridium difficile Ribotyp 027 / Stefanie Gemein. Mathematisch-Naturwissenschaftliche Fakultät." Bonn : Universitäts- und Landesbibliothek Bonn, 2011. http://d-nb.info/1017217394/34.
Повний текст джерелаSchneider, Ulrich Johannes. "Über die Rolle von Bibliotheken in einer digitalisierten Welt." Klartext-Verl, 2010. https://ul.qucosa.de/id/qucosa%3A13056.
Повний текст джерелаSchneider, Ulrich Johannes. "Universitätsbibliothek Leipzig." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-157007.
Повний текст джерелаRambelli, Daniele. "Studio petrografico delle vulcaniti permiane nell’area di Ponte Gardena – Barbiano (BZ)." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2019.
Знайти повний текст джерелаSchneider, Ulrich Johannes. "Über die Rolle von Bibliotheken in einer digitalisierten Welt." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-158226.
Повний текст джерелаRibeiro, Paulo Leonardo Lima. "Efeito da glicerina residual do biodiesel e de estirpes microbianas (Cupriavidus necator IPT 027 e Burkholderia cepacia IPT 438) na produção, propriedades e composição de copolímeros de polihidroxialcanoatos." Universidade Federal da Bahia. Escola Politécnica, 2012. http://repositorio.ufba.br/ri/handle/ri/18621.
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Os polihidroxialcanoatos (PHAs) são poliésteres produzidos por um grande número de estirpes bacterianas, em condições de crescimento limitante. Estes polímeros são completamente biodegradáveis e, por conseguinte, materiais alternativos para fins de substituição dos temoplásticos sintéticos. No entanto, os PHAs, ainda, não têm sido capazes de competir com as resinas convencionais, devido ao elevado custo de processo. Uma forma possível de reduzir os custos de produção é a utilização de fontes de carbono mais baratas, como os coprodutos da indústria do biodiesel. Deste modo, estirpes de Cupriavidus necator IPT 027 e Burkholderia cepacia IPT 438 foram utilizadas, em estudo, a fim de sintetizar PHAs a partir de distintas glicerinas residuais do biodiesel (GRBs) derivadas, por sua vez, do processamento do biodiesel de soja (GRB I), óleos e gorduras residuais (GRB II) e mamona (GRB III). Diferentes variáveis foram mantidas constantes durante a produção de PHA, obtendo-se um percentual máximo de extração de 71,07 %, quando se fez uso da cepa Cupriavidus necator IPT 027 em cultivo com GRB II. As análises de CG-MS revelaram copolímeros de PHAs com hidroxiésteres de cadeia curta (3HB) e de cadeia média (3HTD, 15HPD e 11HHD), com distintas frações em %mol. Tais resultados relacionam-se com o meio de cultivo, as altas massas moleculares obtidas (552 kDa a 8240 kDa), as temperaturas de fusão (139,8 ºC a 175,9 ºC) e os graus de cristalinidade verificados por DRX (35,92 % a 66,07 %) e DSC (33,30 % a 57,80 %). Além disso, observou-se uma versatilidade da cepa Burkholderia cepacia IPT 438 perante as fontes de carbono estudadas, principalmente no que concerne às propriedades dos biopoliésteres. Portanto, majoritariamente, os biopolímeros produzidos obtiveram, segundo a literatura, propriedades aplicáveis em nível industrial, porém torna-se fundamental o controle otimizado do processo de cultivo, a fim de potencializar a produção e propriedades de copolímeros de PHAs, adequando-os as mais diversas aplicações tecnológicas.
Кириленко, Поліна Андріївна, та Валентин Олександрович Бутович. "Електронні бібліотеки: проблеми створення та перспективи розвитку". Thesis, Національний авіаційний університет, 2021. https://er.nau.edu.ua/handle/NAU/50510.
Повний текст джерелаThe article deals with the generalization of existing research experience. Problems of creation, development and functioning of the electronic library as a component modern information-educational environment. The approaches to definition are considered the notion of "electronic library". The purpose of creating, specific features are determined, functional capabilities, basic functions of the electronic library.
У статті здійснено узагальнення існуючого досвіду дослідження проблем створення, розвитку та функціонування електронної бібліотеки як складової сучасного інформаційно-освітнього середовища. Розглянуто підходи до визначення поняття «електронна бібліотека». Визначено мету створення, специфічні особливості, функціональні можливості, основні функції електронної бібліотеки.
Hazel, Susan Jane. "Effects of treatment with IGF-I, GH and IGF-2 plus GH in a rat model of chronic renal failure /." Title page, contents and abstract only, 1995. http://web4.library.adelaide.edu.au/theses/09PH/09phh429.pdf.
Повний текст джерелаDrost, Vincent. "Le monnayage de l'empereur Maxence (306-312 ap. J. -C. ) et l'histoire politique et économique de la fin de l'époque tétrarchique." Paris 1, 2011. http://www.theses.fr/2011PA010528.
Повний текст джерелаKoop, Ulrike. "Wertzumessung für Öffentliche Bibliotheken." Doctoral thesis, Humboldt-Universität zu Berlin, 2017. http://dx.doi.org/10.18452/18125.
Повний текст джерелаThe aim of this study is to determine the economic value of a public library in a medium-sized town in Germany. The factors influencing the value must first be identified and the population’s (both library users and non-users) appreciation must be compared with those of their political and administrative representatives. In the theoretical section of this study the current state of research in value and impact assessment will be explained and presented within the context of impact-oriented administration (New Public Management). The concept of lifestyles will also be explained. The main, empirical section of the study concentrates on the assessment of a written questionnaire (mail survey) on the economic value of the Melle Public Library. Two parallel questionnaires were conducted; one for the population of the city of Melle and one for their political and administrative agents. In addition to the economic rating of the library, expressed as willingness-to-pay (under application of the contingent valuation method) at the core of the assessment, the analysis focuses on the aspects of lifestyle types according to Gunnar Otte, library use and position within the family or life cycle as influencing factors. The expressed willingness-to-pay of the population will be directly compared with that of the politicians. A ratio of willingness-to-pay and the result-per-resident (an economic value) will be generated and thereby an indicator of value determined.
Tournieroux, Anne. "Les bibliothèques privées en France et en Italie à la fin du Moyen Âge (1400-1520)." Thesis, Paris 1, 2017. http://www.theses.fr/2017PA01H103.
Повний текст джерелаThis thesis aims at the comparative study of libraries of laity and clerics in the north of France and northern Italy between 1400 and 1520. The relations between the French and Italian territories are no longer to be demonstrated, marked for the beginning of our period by the progressive resolution of the Great Schism and, for the end, by the Italian wars between 1494 and 1516. In the fifteenth century and up to the beginning of the sixteenth century, cultural phenomena of the first order such as dissemination of humanism and, on the material level, the invention of printing spread throughout Europe. We have chosen to focus on "traditional" categories of possessors such as the secular clergy, but also to emerging categories of possessors, including the bourgeoisie
Hodgson, John. "Class acts : the twenty-fifth and twenty-sixth earls of Crawford and their manuscript collections." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/class-acts-the-twentyfifth-and-twentysixth-earls-of-crawford-and-their-manuscript-collections(3ed36c16-23f9-4b9c-85d5-21070eea9984).html.
Повний текст джерелаDiouf, François Malik. "Les ressources numériques dans l'enseignement supérieur sénégalais : état des lieux et étude prospective." Thesis, Dijon, 2014. http://www.theses.fr/2014DIJOL042/document.
Повний текст джерелаIt is in the context of poverty or information exclusion that the massive dissemination of information and technology tools in Senegalese academic libraries responds to an urgent need for transformation and improvement of operational modes as well as modernization of services for different audiences, in particular students. Currently, in almost all academic and research libraries of Senegal digitization activities that crossed the rise of the Internet are being developed. This has created a real increasing effect of digital resources, by the establishment of means of creation and by expansion of access and of sharing of scientific and technical information in higher education institutions. The development of information technology and communication - the true vectors of documentary practices among Senegalese academic libraries users – together with the growth of digital resources, will inevitably turn the traditional relationship between students and libraries upside down. The objective of this thesis is, therefore, to study the transformation of the librarians’ profession, information culture of students, and their use of digital resources, with regard to sociocultural, political, economic, and sociotechnical contexts of Senegal; and in the context of the information society under construction. Thus, through this study, a prospective analysis devoted to the development and the emergence of libraries can be constructed
Malosse, Pierre-Louis. "Libanios, discours LIX : texte, traduction et commentaire." Montpellier 3, 1998. http://www.theses.fr/1998MON30047.
Повний текст джерелаBruhat, Marie-Odile. "Les Carmina Figurata de Publilius Optatianus Porfyrius : la métamorphose d'un genre et l'invention d'une poésie liturgique impériale sous Constantin." Paris 4, 1999. http://www.theses.fr/1998PA040320.
Повний текст джерелаOptatianus Porfyrius transcended the Alexandrian figurated poem (technopaegnia). His square-like poems display internal pictures drawn by clever versus intexti : geometrical patterns, dedications, emblems. This poetry combines influences from epigraphy (characters placement, acrostiches), ornamental arts (mosaic patterns) and mathematics (combinatorics of reading paths and word permutations). To describe his art the poet uses the vocabulary of weaving. His works illustrate graphically this idea of the text as an intertwining. The weaving metaphor reminds of the embroidery: the text/fabric becomes the equivalent of the toga picta of the conqueror. Composed in the period 320-326, Optatianus' Carmina follow emperor Constantine steps toward a monarchic, dynastic and Christian rule. A parallel study of contemporary coins shows how Optatianus carefully exploits the evolution of the imperial propaganda. His praise give evidence of the Christianization of the executive power, precisely when it keeps connections with the cult of sol. Optatianus also emphasizes the theme of the light, with the purpose to celebrate the constantinian gloria. Optatianus poetry bears traits of the esthetics of the roman 4th century a. D. : a taste for abstraction, symbols and clichés. The vows associated to the renewal of the emperor's charisma give to the Carmina a liturgic value in harmony with the spirit of the main imperial celebrations
Li, Shi. "Hyper-heuristic cooperation based approach for bus driver scheduling." Phd thesis, Université de Technologie de Belfort-Montbeliard, 2013. http://tel.archives-ouvertes.fr/tel-00976554.
Повний текст джерелаMorlet, Sébastien. "L'apologétique chrétienne à l'époque de Constantin : la démonstration évangélique d'Eusèbe de Césarée." Paris 4, 2006. http://www.theses.fr/2006PA040220.
Повний текст джерелаThe Demonstratio evangelica is the second part of a large twofold apologia written by Eusebius of Caesarea (c. 265 – 339/340). Though this apologia is the longest one in all Antiquity, it has never been investigated in detail. The Demonstratio evangelica is at the same time an antijewish tract, a continuation of the antipagan controversy dealt with in the first part of the apologia (the Praeparatio evangelica), and above all the climax of an organic work which Eusebius conceived as a teaching process. This study emphasizes the place of the Demonstratio evangelica within the antijewish and antipagan traditions, by a throrough analysis of its polemical background and argumentation. Eusebius’ scholarly project is new within the apologetic tradition. The bishop of Caesarea applies to the controversy methods and commentaries he owes to his spiritual master Origen. In that respect, the Demonstratio evangelica is an original work, situated half-way between controversy and research, which influenced several later polemists
Mezin, Florent. "Des troupes alpines aux troupes de montagne : (1962-2012) : histoire d'un processus de légitimation professionnelleet d'affirmation d’une identité militaro-territoriale." Thesis, Université Grenoble Alpes (ComUE), 2016. http://www.theses.fr/2016GREAH035.
Повний текст джерелаSince their creation in 1888, the Alpins form a separate subdivision within the French Army. The primary and specific mission of these territorially very marked units is to defend the Alpine border. In 1962, after two world wars and two decolonization wars, France enters a new era. In response to the threat, the nuclearization of the army is decided by the country. In this context of cold war, the Alpines units are merely territory troops. They become marginalized and hardly find a place as well in the new safety and national defence features as within the Alpins territories which are undergoing profoundchange. However, in 1983, to widespread surprise, the 27e Division Alpine joins the Force d’Action Rapide and takes part in its first external operation. This OPEX (EXternal OPeration) in Lebanon marks a beginning of rebirth for the Alpins. Their operational legitimacy was established by the deployment of mountain soldiers in Yugoslavia in the 1990s and then in Afghanistan in the 2000s. In the XXIth century, the henceforth professional army of the Alps occupies a novel place in the mountain territories and plays a new role to the Alpin societies. Indeed, the struggle for legitimation, appreciation and influence of the “mountain specificity” of the Alpin troops is not to be won on the battlefields only. The search for new traditions in an attempt to rebuild a mountain military identity,the organisation of various ceremonies in the public space, the reconstruction of a common heritage are all weapons in the hands of the 27e Brigade d’Infanterie de Montagne command for the purpose of continuing to exist in spite of the “perpetual reform” of the “Défense française”. The 27e Brigade d'Infanterie de Montagne remains guardian of the traditions of the former Alpins. The 27e BIM stays the emergency brigade of the French land army. Due to its acknowledged operational capabilities, it implements its specific expertise in various theatres, within the national territory or outside
Teixeira, Manuel Ferreira Salavisa. "Infecção nosocomial por Clostridium difficile : caracterização da estirpe epidémica 027." Master's thesis, 2014. http://hdl.handle.net/10451/24359.
Повний текст джерелаThe incidence and severity of Clostridium difficile infection increased exponentially during the last decade, and is currently the third most prevalent nosocomial infection in the Western world. This phenomenon is directly correlated with the spread of an epidemic strain, classified as ribotype 027, characterized by the increased production of toxins A and B, production of another toxin (binary toxin) and high-level resistance to fluoroquinolones. Using a combination of strategies in the management of nosocomial Clostridium difficile infection that is focused not only on the application of barrier methods for preventing horizontal spread (hand washing, isolation, environmental hygiene), but also in reducing the consumption of " target- antibiotics " associated with a higher risk of Clostridium difficile infection was shown to be effective in reducing the incidence and severity of nosocomial C. difficile outbreaks. Currently one of the most significant limitations of therapeutic management of Clostridium difficile infection is the high rate of recurrence after treatment. In this respect , the emergence of new pharmacological agents such as fidaxomicin or research in the immune therapy with anti - toxin A and B vaccines and antibodies , has shown significant results reported by several clinical trials and could play in the future , a role first-line approach in the Clostridium difficile infection. This work reviews current literature regarding the particular characteristics associated with the epidemic strain 027, the prevention and control of nosocomial outbreaks of Clostridium difficile infection, current treatment options and new pharmacological approaches currently under investigation.
A incidência e gravidade da infecção por Clostridium difficile aumentaram exponencialmente no decorrer da última década, sendo actualmente a terceira infecção nosocomial mais prevalente no mundo ocidental. Este fenómeno correlaciona-se directamente com a disseminação de uma estirpe epidémica, classificada como ribótipo 027, caracterizada por uma produção aumentada de toxinas A e B, produção de uma terceira toxina (toxina binária) e elevada resistência a fluoroquinolonas. A utilização de uma combinação de estratégias na abordagem do surto nosocomial de infecção por Clostridium difficile que assente não só na aplicação de métodos barreira para prevenção da disseminação horizontal (lavagem das mãos, isolamento, higiene ambiental), mas também na redução do consumo de “antibióticos-alvo” associados a maior risco de colonização por C. difficile, mostrou ser efectivo na redução da incidência e gravidade da infecção por Clostridium difficile nosocomial. Actualmente uma das limitações mais significativas do manejo terapêutico da infecção por Clostridium difficile é a elevada taxa de recorrência pós-tratamento. Neste domínio, a emergência de novos agentes farmacológicos como a fidaxomicina ou a investigação no âmbito da terapia imunológica com anticorpos anti-toxina A e B e vacinas, tem revelado resultados significativos reportados por diversos ensaios clínicos, podendo vir a desempenhar no futuro, um papel de primeira linha na abordagem da infecção por Clostridium difficile. Este trabalho tem por objectivo a revisão literária das características particulares associadas à estirpe epidémica 027, medidas de prevenção e controlo de surtos nosocomiais de infecção por Clostridium difficile, opções terapêuticas actuais e novas abordagens farmacológicas em estudo.
Hill, Warren G. (Warren Gary) 1962. "Sulphation of glycosaminoglycans in cystic fibrosis / by Warren Gary Hill." 1995. http://hdl.handle.net/2440/18637.
Повний текст джерелаBibliography: p. 283-315.
xiv, 315 p., [3] leaves of plates : ill. (one col.) ; 30 cm.
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
To establish whether altered sulphation in cystic fibrosis could be demonstrated in different experimental systems, by focusing on glycosaminoglycans. The second aim was to establish the molecular basis for such a phenomenon.
Thesis (Ph.D.)--University of Adelaide, Dept. of Paediatrics, 1995
Montoya, Delilah. "Corazon Sagrado = Sacred Heart /." 1993. http://rmoa.unm.edu/docviewer.php?docId=nmupict2001-027.xml.
Повний текст джерелаUniversity of New Mexico, Dept. of Art and Art History, M.F.A. thesis project. Book (21 p. ; 23 cm.) is housed within the inside cover of portfolio and is held in place with a leather belt. Includes bibliographical references.
Paesler, Ferdinand. "Regionalentwicklung und Mensch-Umwelt-Interaktion - Zwei Fallbeispiele aus Kenia und der Demokratischen Republik Kongo." Doctoral thesis, 2015. https://doi.org/10.25972/WUP-978-3-95826-027-6.
Повний текст джерелаDevelopment as the fundamental concept of Development Studies, Politics and Cooperation is an inhomogeneously used term with a variety of different connotations. This dissertation gives in its theoretical part a short introduction to the history of development thought, focused especially on geographical approaches concerning regional development as well as the relationship between development and space. Thus, local participation and political ecology are identified as suitable instruments for analysing dynamics and actual processes of local development. So the stakeholder- and context-oriented approach leads to development as a result of human-environment interactions. To confirm the usability of the theoretical implications mentioned above, the second part contains a case study research to describe and analyse the regional development and its spatial and social effects in two field study areas. The actual developments in both regions ¬- Wasini Island in Kenya and Mampu/Mbankana in the Democratic Republic of the Congo - are thereby heavily affected by external influences, namely international tourism and nature conservation (Wasini), respectively a development cooperation project carried out by the Hanns Seidel Foundation (Mampu/Mbankana). The analyses also take into account the particular natural-spatial, political and historical context, being the framework for local stakeholders‘ actions. In both study areas events changing the situation can be found, which by large parts of local populations are experienced as exogenous crises: a dramatic decline of tourist arrivals due to the post-electoral riots (2007/08 Kenyan Crisis) in Wasini and the phasing out of Hanns Seidel Foundation‘s financial support in Mampu/Mbankana since 2009, including intraregional shifts of responsibilities and influence. As a result of both the theoretical and empirical findings, development on a regional level is analysed as a stakeholder- and context-dependent process which consists of the accumulated two-way human-environment interactions within a region. This perspective is founded on the tradition of geographical possibilism, because it shows the natural, geographical and social environments framing, but not determining, human actions and thus development processes
Wei, Wei. "Data mining using neural networks for large credit card record sites." Thesis, 2001. http://library1.njit.edu/etd/fromwebvoyage.cfm?id=njit-etd2001-027.
Повний текст джерелаPetrov, Plamen V. "Applications of agent architectures to decision support in distributed simulation and training systems." Thesis, 2000. http://library1.njit.edu/etd/fromwebvoyage.cfm?id=njit-etd2000-027.
Повний текст джерелаAn, Yoo Jung. "Ontology learning for the semantic deep web." Thesis, 2008. http://library1.njit.edu/etd/fromwebvoyage.cfm?id=njit-etd2008-027.
Повний текст джерела