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Автор: Grafiati

Опубліковано: 8 червня 2024

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1

Mattioli, Paolo <1966&gt. "Qualificazione e valorizzazione della agrozootecnica nel sistema delle aree protette." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2007. http://amsdottorato.unibo.it/580/1/Tesi_Mattioli.pdf.

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2

Dal, Pozzo Fabiana <1978&gt. "Virus animali come modello nello studio in vitro dell'attività di molecole antivirali: applicazioni future in medicina veterinaria e nei confronti di virus filogeneticamente correlati responsabili di patologie umane." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2007. http://amsdottorato.unibo.it/531/1/dal_pozzo_fabiana_tesi.pdf.

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3

Aimon, Akfiny Hasdi [Verfasser], Thomas [Akademischer Betreuer] Michely, and Liu Hao [Akademischer Betreuer] Tjeng. "Thin films preparation of Fe(3−x)Co(x)O(4) with x = 0, 0.1, 0.5, 1 and their properties / Akfiny Hasdi Aimon. Gutachter: Thomas Michely ; Liu Hao Tjeng." Köln : Universitäts- und Stadtbibliothek Köln, 2014. http://d-nb.info/1061121240/34.

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4

Vagelli, Valerio [Verfasser], and W. de [Akademischer Betreuer] Boer. "Measurement of the cosmic (e+ + e-) flux from 0.5 GeV to 1 TeV with the Alpha Magnetic Spectrometer (AMS-02) on the International Space Station / Valerio Vagelli. Betreuer: W. de Boer." Karlsruhe : KIT-Bibliothek, 2014. http://d-nb.info/1067496769/34.

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5

Müller, Sebastian [Verfasser], and Jörn [Akademischer Betreuer] Wilms. "Observations of the X-ray Pulsars XTE J1946+274, 4U 0115+634, and GX 304-1 / Sebastian Müller. Gutachter: Jörn Wilms." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2013. http://d-nb.info/1065380526/34.

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6

Müller, Sebastian Verfasser], and Jörn [Akademischer Betreuer] [Wilms. "Observations of the X-ray Pulsars XTE J1946+274, 4U 0115+634, and GX 304-1 / Sebastian Müller. Gutachter: Jörn Wilms." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2013. http://d-nb.info/1065380526/34.

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7

Martinez, Gandara Alejandra <1980&gt. "The Law and Economics of Eco-labels." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/5630/1/Thesis_Print_Version_%282%29.pdf.

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Eco-labels and certification are one of the many environmental policy tools that have been under scrutiny in recent years. This is because the damages of environmental degradation are becoming more apparent over time. Hence there is a pressure to come up with tools that help solve even small parts of the problem. Eco-labels have been around for over 30 years. However the market, the environment and eco-labels have changed drastically during this period. Moreover, in the last 5 years there has been a sudden increase in eco-labels making them more visible in the market and to the average consumer. All this has made evident that little is known about the effectiveness of eco-labels as environmental policy tools. Hence, there is a call to find answers regarding the actual effects of eco-labels on the market and on the environment. While this work cannot address whether eco-labels have an environmental impact it addresses the effects of eco-labels on the markets. Moreover, this work aimed to find the role of law in eco-labelling. In addition, it aims to find a legal solution that would improve the performance of eco-labelling and certification.

8

Frassetto, Marco <1991&gt. "Plasma Production via 6 ns Pulsed Laser at 1064 and 532 nm wavelengths on Nanostructured Targets." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amsdottorato.unibo.it/9493/1/Tesi_Marco_Frassetto.pdf.

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This thesis presents the result of a study, within the scope of the PLANETA experiment (an INFN research program), on the effect of nanostructures on laser-matter interaction. Specifically, the plasma created on targets containing metal nanowires when irradiated with a laser pulse 6 ns long, at 1064 and 532 nm wavelength, with a power density of about 1 · 1012 W/cm2 . Laser-produced plasma is of interest for a wide range of scientific and technological application, from using them as a source of X-rays to the possibility of nuclear fusion thanks to the high densities and temperatures which can be reached inside the plasma. However, most applications are constrained by the very limited penetration of laser energy into matter, due to the rapid formation of a reflective critical surface of dense plasma. PLANETA experiment was meant to investigate if targets with metal nanowires (thin cylinders with diameter < 100 nm, smaller than the laser’s wavelength) could lead to production of a hotter and/or longer lived plasma compared to bulk metal. The proposed mechanism would be a deeper penetration of laser light into the targets. This could lead to volumetric, instead of superficial heating, and thus to the production of a hotter and denser plasma compared to a bulk metal target. Targets were produced at the electron microscopy lab of INFN Bologna, with nanowires of different geometrical parameters and different metals. They were irradiated with a Nd-Yag laser at the INFN Laboratori Nazionali del Sud in Catania, and the resulting plasmas were observed with detectors of several kinds to compare them with plasmas from bulk metals. A different INFN facility at the Department of Physics, University of L’Aquila, equipped with a 532 nm wavelength laser was available to the PLANETA experiment.

9

Cardillo, Elena. "A Lexi-ontological Resource for Consumer Healthcare: The Italian Consumer Medical Vocabulary." Doctoral thesis, University of Trento, 2011. http://eprints-phd.biblio.unitn.it/570/1/PhD-Thesis-Elena-Cardillo.pdf.

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In the era of Consumer Health Informatics, healthcare consumers and patients play an active role because they increasingly explore health related information sources on their own, and they become more responsible for their personal healthcare, trying to find information on the web, consulting decision-support healthcare systems, trying to interpret clinical notes or test results provided by their physician, or filling in parts of their own Personal Health Record (PHR). In spite of the advances in Healthcare Informatics for answering consumer needs, it is still difficult for laypersons who do not have a good level of healthcare literacy to find, understand, and act on health information, due to the communication gap which still persists between consumer and professional language (in terms of lexicon, semantics, and explanation). Significant effort has been devoted to promote access to and the integration of medical information, and many standard terminologies have been developed for this aim, some of which have been formalized into ontologies. Many of these terminological resources are used in healthcare information systems, but one of the most important problems is that these types of terminologies have been developed according to the physicians’perspective, and thus cannot provide sufficient support when integrated into consumer-oriented applications, such as Electronic Health Records, Personal Health Records, etc. This highlights the need for intermediate consumer-understandable terminologies or ontologies being integrated with more technical ones in order to support communication between patient-applications and those designed for experts. The aim of this thesis is to develop a lexical-ontological resource for consumer-oriented healthcare applications which is based on the construction of a Consumer-oriented Medical Vocabulary for Italian, able to reflect the different ways consumers and patients express and think about health topics, helping to bridge the vocabulary gap, integrated with standard medical terminologies/ontologies used by professionals in the general practice for representing the process of care, by means of Semantic Web technologies, in order to have a coherent semantic medical resource useful both for professionals and for consumers. The feasibility of this consumer-oriented resource and of the Integration Framework has been tested by its application to an Italian Personal Health Record in order to help consumers and patients in the process of querying healthcare information, and easily describe their problems, complaints and clinical history.

10

Manna, Alice <1991&gt. "Measurement of the 235 U(n,f) cross section relative to the neutron-proton elastic scattering up to 500 MeV at n_TOF." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amsdottorato.unibo.it/9954/1/Manna_Alice_tesi.pdf.

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Neutron cross-section standards are fundamental ingredients for both measurements and evaluations of neutron-induced reaction cross sections. This is the case of 235U(n,f) cross section: one of the most important standard cross sections at thermal neutron energy and between 0.15 MeV and 200 MeV. Above 200 MeV this reaction plays an important role for several applications, from biological effectiveness, via nuclear astrophysics, to nuclear technology, as well as for fundamental nuclear physics. However, no measurement exists for energies above 200 MeV. This led to a request for new absolute measurements of 235U(n,f) cross section, in order to extend the precision and possibly to establish it as a standard up to 1 GeV. The n_TOF facility at CERN offers the possibility to study such reaction thanks to the wide neutron energy spectrum available in its experimental area, from thermal to 1 GeV. A dedicated measurement campaign was carried out to provide accurate and precise cross-section data of the 235U(n,f) reaction in the energy region from 10 MeV to 500 MeV. The experimental setup consisted of two chambers to detect the 235U fission events, while the neutron flux was simultaneously measured by exploiting the neutron-proton scattering process using three Proton Recoil Telescopes. In this PhD thesis the development, implementation and characterisation of the two telescopes under the responsibility of the INFN are discussed, as well as the analysis of the data acquired during the campaign. In this measurement, the n_TOF neutron flux in the energy interval between 10 and 500 MeV was measured for the first time. In addition, the analysis of one of the two chambers dedicated to the measurement of fission events is presented in detail. From these data, the 235U(n,f) cross section was determined and represents, at this time, the unique measure of this kind.

11

Santos, Salazar Igor <1978&gt. "Potere centrale e comunità locali nell'Emilia Orientale nella transizione dalla Tarda Antichità al Pieno Medioevo: il territorio di Persiceta (500-1000)." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2007. http://amsdottorato.unibo.it/248/1/tesi.pdf.

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12

Confalonieri, Michele. "Systems development for diagnostics and dexterity rehabilitation by means of touchscreen technology." Doctoral thesis, University of Trento, 2016. http://eprints-phd.biblio.unitn.it/1706/1/PhD_Thesis_MicheleConfalonieri.pdf.

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This thesis stems from the need to implement the existing technology in the rehabilitation. Smartphones, touch screen technology, apps, which are a common part of our daily life don’t find an application in clinical practice. The aim of this work is to verify the effectiveness of using this technology both in the hospital and outside. The exergames we developed can be played on usual touchscreen devices, on personal computers and on the custom device built in our laboratory. The device used during our experimentation is now installed in a medical facility with other latest generation medical devices like the Armeo and two different types of exoskeletons. In the first part of this project we focused on developing some exergames oriented to the rehabilitation of persons affected by strokes and in the characterization of people affected by Parkinson. In the second part, because of the strong correlation between physical activity and neurocognitive functions we decided to use the device since the very beginning of the rehabilitation process, developing some kind of exergames used also to monitor patients during this phase. Thanks to the collaboration with the medical staff we analysed and summarized the macro areas and the neurocognitive functions involved during the rehabilitation process. After that, we analysed some of the usual exercises given to the patients highlighting the neurocognitive functions involved, and for each exercise we defined some indicators, like touch precision and its standard deviation, mean of force and its standard deviation, total time to execute the test, number of errors, etc... To develop the exergames based on what we decided with the medical staff we used the game engine called Unity3D and we wrote the code of the exergames in C#. After a first test phase in which the medical staff tried the exergames and gave us a feedback, we fixed the bugs and decided to integrate all the exergames in a common platform. Then, we defined an official procedure for the rehabilitation program based on this new method in order to submit it to the ethics committee. In a second phase, the medical staff selected the group of patients to be assigned to the test program, and defined some useful indicators about the neurocognitive functions involved. Finally, to validate the efficiency of this protocol, patients need to executed the exergames for a certain time, after which the medical staff measured the indicators. In this way we were able to validate the efficiency of the exergames and of the device installed. By working in the European project NoTremor we developed two different type of test with the aim of characterize a model of people affected by Parkinson.

13

Wiese, Maria. "Dissecting the ß-catenin-dependent and -independent functions of BCL9 and BCL9-2 in intestinal tumorigenesis." Doctoral thesis, 2013. http://hdl.handle.net/11858/00-1735-0000-0015-9FC6-1.

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Der hochkonservierte Wnt/ß-Catenin-Signaltransduktionsweg spielt eine wichtige Rolle während der Embryonalentwicklung, der Homöostase und der Tumorgenese in Adulten. Die BCL9 Proteine wurden zunächst als Kofaktoren dieses Signalweges identifiziert. Entsprechend agiert BCL9/Legless als essentieller Wnt/ß-Catenin-Kofaktor in Drosophila. Jedoch scheint die Rolle von BCL9 und BCL9-2, der Orthologe von Legless, in Vertebraten komplexer zu sein. Des Weiteren wurden die genauen Funktionen der BCL9 Proteine während der intestinalen Homöostase und Tumorgenese bislang wenig untersucht. Es konnte jedoch bereits gezeigt werden, dass BCL9-2 in intestinalen und Mammakarzinomen verstärkt expremiert wird. Diese Arbeit beschreibt erstmalig den Einfluss und die Funktion von BCL9-2 während der intestinalen Tumorgenese. BCL9-2 beinflusst die Tumorprogression positiv durch Verstärkung des Wnt/ß-Catenin-Signaltransduktionsweg und der Expression von Zielgenen, die Tumorwachstum und -invasion vermitteln. Zudem aktiviert BCL9-2 die Transkription von ß-Catenin-unabhängigen Genen durch einen neuartigen Mechanismus. Im Gegensatz zu BCL9, welches in allen humanen und murinen intestinalen Zelltypen expremiert wurde, beschränkte sich die BCL9-2 Expression auf die Zotten des Darmes. Die Wnt/ß-Catenin-positiven Krypten hingegen zeigten keinerlei BCL9-2-Expression auf, was darauf hinweist, dass BCL9-2 für den Wnt/ß-Catenin-Signalweg bei der intestinalen Homöostase entbehrlich ist. Während jedoch BCL9 Proteinlevel in Kolontumoren, im Vergleich zum normalen Epithel, unverändert blieben, wurde BCL9-2 bereits in frühen Stadien der Tumorgenese und in 90% aller Kolonkarzinome stark expremiert. Darüber hinaus führte transgene Überexpression von BCL9-2 im Darm von K19-BCL9-2;APCMin/+ Mäusen zu einer verstärkten Formation von Adenomen, deren Invasion und einem verringerten Überleben der Versuchstiere. Wie anhand von TOP/FOP Luciferase Reportergen-Versuchen gezeigt werden konnte, korrelierte die Stärke der BCL9-2-Proteinexpression mit der Aktivität des Wnt/ß-Catenin-Signalweges in Kolonkarzinomzellen. Zudem regulierte BCL9-2 die Transkription einiger ß-Catenin-abhängiger und darüber hinaus ß-Catenin-unabhängiger Zielgene, die bei der Tumorentstehung eine wichtige Rolle spielen. Des Weiteren zeigt diese Arbeit, dass in Kolonkarzinomzellen die BCL9-2 abhängige Transkription von CDX1 und CDX2 durch SP1-bindende Elemente über deren proximale Promotoren vermittelt wurde. Mittels Immunpräzipitation konnte zudem eine Interaktion zwischen BCL9-2 und SP1 in Kolonkarzinomzellen bestätigt werden. Zusammenfassend zeigt diese Arbeit, dass BCL9-2-Überexpression in frühen Phasen der intestinalen Tumorgenese die Progression von benignen Tumoren in invasive Karzinome fördert. Diese Eigenschaft wird durch verschiedene Mechanismen vermittelt: Zum einen verstärkt BCL9-2 die Expression einiger Wnt/ß-Catenin-abhängiger Zielgene; zum anderen reguliert BCL9-2 ß-Catenin-unabhängige Gene, die für die Tumorgenese eine wichtige Rolle spielen. Diese Funktion wird vermutlich durch die Bindung an SP1 Transkriptionsfaktoren und damit an die Promotoren von BCL9-2 Zielgenen vermittelt, was zu der verstärkten Expression von Genen führt, die die Tumorprogression und Invasion fördern.

14

Lv, Guohua. "Protein Structure Characterization by Solid-State NMR: Structural Comparison of Mouse and Human alpha-Synuclein Fibrils, Sparse 13C Labeling Schemes, and Stereospecific Assignment of Val and Leu Prochiral Methyl Groups." Doctoral thesis, 2013. http://hdl.handle.net/11858/00-1735-0000-0015-983C-F.

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15

Han, Sihui. "Le comportement d'hystérésis des solides et sa description par un schéma à mémoire discrète : le cas des aciers inoxydables." Habilitation à diriger des recherches, 1985. http://tel.archives-ouvertes.fr/tel-00319507.

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Étude du comportement d'un acier inoxydable 316L et d'un Inconel 718 dans le cadre d'un schéma thermomécanique à mémoire discrète constitué d'une équation multivoque, d'un critère d'inversion et d'un algorithme. Analyse détaillée des propriétés du comportement d'hystérésis pure. Etude des modules tangents aux courbes de charge. Mise en évidence de la restauration des propriétés du matériau après inversion et de la non-existence d'une discontinuité elastique-plastique dans le diagramme contrainte-déformation. Description de l'écrouissage en déformation à partir d'une analyse de la microstructure