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Zeng, Kai. "Some problems in harmonic analysis on twsited crossed products." Electronic Thesis or Diss., Bourgogne Franche-Comté, 2023. http://www.theses.fr/2023UBFCD048.
This thesis is devoted to the study of some problems in the harmonic analysis on twisted crossed products defined by twisted actions of a locally compact group G on a von Neumann algebra M. It consists of two parts. The first concerns twisted crossed products and their Fourier and Schur multipliers. We prove that the property of being QWEP for the twisted von Neumann algebra of a group G is independent of the underlying 2-cocycle and that the completely bounded Lp-Fourier multipliers on this twisted algebra are also independent of the 2-cocycle. Under the hypothesis of an amenable action, we establish several transference results between the Fourier and Schur multipliers on the noncommutative Lp spaces of the twisted crossed product.In the second part, we study Fourier multiplier commutators on the twisted crossed product of an Euclidean space. We characterize their Schatten p-class membership by that of their symbols in the associated Besov space. In addition, this part contains a formula on the Dixmier trace, which also gives us a characterization of the weak Schatten p-class membership of these commutators by a Sobolev space. In particular, our results apply to the case of quantum Euclidean spaces
Zhou, Quan. "Performance portfolio." Thesis, University of Salford, 2017. http://usir.salford.ac.uk/43699/.
Themelis, Kristy. "Investigating the effects of multisensory illusions on pain and body perception." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43299/.
Wang, Hong. "Study of Chinese household cooking practices : energy and cooking fumes." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43499/.
Bruno, Cosima. "Contemporary Chinese poetry in translation." Thesis, SOAS, University of London, 2003. http://eprints.soas.ac.uk/4399/.
Parmar, Manish M. "Polymorph selection with morphology control using solvents and additives." Thesis, Liverpool John Moores University, 2016. http://researchonline.ljmu.ac.uk/4399/.
Di, Staso Nicola <1981>. "Modificazioni soggettive del rapporto obbligatorio e garanzie reali." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4399/.
The study about the subjective side of the legal relationship is pivotal in the theory of the obligation. The question is whether the modification of one or even both parts always entails its extinction or whether its objective unity is preserved. The answer has been different depending on historic ages. In the Roman law, the variation of any subject entailed the extinction of the relationship and the constitution of a new obligation (subjective novation). Such solution has been opposed by modern legislators, for whom, in case of modification of the personae, not the extinction of the relationship, but only the change of one of its elements happens. As for the property secutities, especially the mortgage, the essential general principles are the specialty and the accesority. The latter feature is crucial in case of subjective modification of the relationship, and this emerges in the dissertation about the singles typologies of the Italian Civil Code that determines it, in both active and passive point of view. In order to quicken the transfer of the credit, in the 2007 the “Bersani Decree” (on the portability of the loan), that allowed to remove the ties of the credit circulation in the banking relationships area, was approved. The features of the modification of the obligatory relations, however, can undermine the effectiveness of the Bersoni reform. This is the reason why some scholars support a vast review of the whole mortgage law, removing, in the light of what occurred in other European systems, the requirement of the acessority of the tie. Nevertheless, due to the risks related to this reform, refining the mechanism of improvement of the portability is considered preferable, while removing the criticalities without compromising the certainties of the present system, of which the acessority of the mortgage is an important foundation.
Coyle, Jesse Aaron. "Optimization of nuclear, radiological, biological, and chemical terrorism incidence models through the use of simulated annealing Monte Carlo and iterative methods." Thesis, Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/43599.
Hostetler, Dana M. "New methods for the examination of poor quality medicines." Thesis, Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/43699.
Domingues, Lidiane Priscila. "Fécula de batata na alimentação de cães." reponame:Repositório Institucional da UFPR, 2016. http://hdl.handle.net/1884/43399.
Co-orientadora : Profª. Drª. Ana Rosalia Mendes
Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Agrárias, Programa de Pós-Graduação em Zootecnia. Defesa: Curitiba, 24/03/2016
Inclui referências : f. 24-27-38-52-53
Área de concentração : Nutrição e produção animal
Resumo: A proximidade entre os cães e seus tutores induz a busca de dietas cada vez mais elaboradas, contribuindo para o surgimento de novos nichos no setor. É o caso das chamadas dietas grain free, caracterizadas por elevados teores de proteína e lipídios e substituição dos grãos por fontes mais complexas de amido, como é o caso da batata. Objetivou-se avaliar as características do extrusado, os coeficientes de digestibilidade aparente (CDA), características fecais e palatabilidade de dietas com crescentes níveis de fécula de batata (FBT) para cães adultos e filhotes. Quatro dietas contendo 0, 10, 20 e 30% de FBT, em substituição ao milho, foram avaliadas em três experimentos. O primeiro consistiu na avaliação das características físicas das dietas durante e após seu processamento. Para digestibilidade e características fecais (Experimento 2) foram comparadas as quatro dietas, com 8 cães adultos (7 anos) e 16 filhotes (6 meses). No teste de preferência alimentar (Experimento 3) foram comparadas as dietas: 0 vs 10% de FBT e 0 vs 30% de FBT, utilizando 16 cães filhotes. Dietas com maior nível de FBT apresentaram maior tamanho de extrusado, índice de expansão, maior dureza, e maior número de poros enquanto a densidade foi reduzida (P<0,001). A inclusão de FBT aumentou o gasto com energia mecânica na extrusão. A inclusão de FBT aumentou (P<0,05) os CDA da matéria seca (MS), energia bruta (EB) e energia metabolizável (EM) da dieta, tanto nos cães adultos como em filhotes e da proteína bruta (PB) e amido total (AT) apenas em filhotes. A matéria seca fecal (MSf) elevou-se com a inclusão de FBT nas dietas, tanto para cães adultos como filhotes (P<0,05). A inclusão de FBT nas dietas reduziu os níveis de nitrogênio amoniacal das fezes dos cães filhotes (P<0,05). Os cães preferiram as dietas com maior inclusão de FBT (P<0,05), quando as umidades das dietas foram igualadas. A adição de FBT na dieta resulta em extrusados com alto índice de expansão, baixa densidade e maior tamanho. A FBT é uma boa fonte de amido para cães adultos e principalmente para filhotes, melhorando os coeficientes de digestibilidade da maioria dos componentes da dieta e aumentando a MSf, além de ser palatável. Palavras-chave: amido, extrusão, tubérculo.
Abstract: The proximity between the dogs and their guardians induces the search for ever more elaborate diets, contributing to the emergence of new niches in the sector. This is the case of so-called grain free diets characterized by high levels of protein and lipids and replacement of the grain for more complex sources of starch, such as potato case. This study aimed to evaluate the characteristics of extruded, the apparent digestibility coefficients (ADC), fecal characteristics and palatability of diets with increasing levels of potato starch (FBT) for adult dogs and puppies. Four diets containing 0, 10, 20 and 30% of FBT, replacing corn were evaluated in three experiments. The first consisted in evaluating the physical characteristics of diets during and after processing. For digestibility and fecal characteristics (Experiment 2) four diets were compared with 8 adult dogs (7 years) and 16 young (6 months). In food preference test (Experiment 3) diets were compared: 0 vs 10% FBT and 0 vs 30% FBT using 16 puppies. Diets with higher FBT showed greater size extruded expansion ratio, greater hardness, and greater number of pores while the density was decreased (P <0.001). The inclusion of FBT increased spending on mechanical energy in the extrusion. The inclusion of FBT increased (P <0.05) the ADC of dry matter (DM), gross energy (GE) and metabolizable energy (ME) of the diet, both adult dogs and puppies and crude protein (CP) and Total starch (aT) only in puppies. Fecal DM (LDM) is increased by the inclusion in diets FBT, both adult dogs and puppies (P <0.05). The inclusion of FBT in the diets reduced ammonia levels in feces of puppies (P <0.05). The dogs prefer diets containing higher inclusion FBT (P <0.05) when the moisture content of the diets were equalized. The addition of FBT in the diet results in extrudates with high rates of expansion, low density and large size. The FBT is a good source of starch for adult dogs and puppies mainly for improving the digestibility of most components of the diet and increasing MSf, and is palatable. Keywords: extrusion, starch, tubercle
Assmann, Ana Luiza Palma Guimarães. "Produção e caracterização de anticorpo policlonal e monoclonal anti-3abc do virus da febre aftosa." reponame:Repositório Institucional da UFPR, 2015. http://hdl.handle.net/1884/43999.
Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Tecnologia, Programa de Pós-Graduação em Engenharia de Bioprocessos e Biotecnologia. Defesa: Curitiba, 27/02/2015
Inclui referências : f.98-108
Resumo: A febre aftosa é uma doença altamente contagiosa que acomete animais biungulados. Tem distribuição cosmopolita, mas é endêmica na Ásia, África e em alguns países da América do Sul, sendo que o Brasil é considerado zona livre com vacinação. No Brasil o controle epidemiológico da doença é realizado mediante a vacinação e vigilância sanitária sendo necessário diagnóstico diferencial entre animais vacinados de portadores do vírus, para provar a ausência da doença. Desta forma é fundamental o desenvolvimento de testes para diferenciar animais vacinados de doentes e para o controle do processo de produção da vacina. A resposta a anticorpos, contra proteínas não estruturais do vírus, tem sido amplamente utilizada para este propósito, como é o caso do ensaio imuno-enzimático-ELISA/EITB. A proteína 3ABC é uma proteína não estrutural do vírus da febre aftosa e está presente em altos níveis no soro de animais infectados. Visando a diferenciação entre animais doentes e vacinados a proteína ABC deve ser removida durante o processo de produção da vacina, para que o animal imunizado não apresente anticorpos detectáveis contra ela. O objetivo deste estudo foi produzir e caracterizar anticorpos policlonal e monoclonal contra a proteína 3ABC do vírus da febre aftosa, para serem utilizados no desenvolvimento de um teste imunoenzimático que permita monitorar os processos de purificação da vacina, para remover as proteínas não estruturais e controle de qualidade das partidas produzidas visando sua aprovação pelos órgãos fiscalizadores como o Ministério da Agricultura Pecuária e Abastecimento (MAPA). Para a produção dos anticorpos policlonal e monoclonal primeiramente foi produzida a proteína 3ABC recombinante a partir do plasmídeo contendo gene que codifica a proteína 3ABC, já com a mutegênese do gene 3ABC no sítio ativo da protease 3Cpro para sua inativação, produzido por Gonzales, 2013. A produção da proteína foi realizada por fermentação da Escherichia coli recombinante em erlenmeyer de um litro e realizada as etapas de semi purificação (anticorpo policlonal) e ou purificação (anticorpo monoclonal). O anticorpo policlonal, produzido em coelhos, apresentou altos títulos a partir de 75 dias pós-imunização. A puriticação foi realizada por cromatografia de afinidade com proteína G, o que resultou em uma imunoglobulina altamente pura, tornando-a mais específica para a proteína de interesse. Para a produção do anticorpo monoclonal foram imunizados camundongos BALB/c por via intramuscular. A fusão realizada originou 217 colônias de hibridomas, sendo 10 deles positivos no tese ELISA indireto. Após clonagem e expansão dos clones positivos, foi realizado o teste de estabilidade permitindo a seleção de dois clones estáveis. Os anticorpos foram caracterizados pelas metodologias de ELISA e Western Blotting e mostraram alta reatividade contra a proteína 3ABC e podem ser utilizados no desenvolvimento do teste ELISA para o monitoramento dos processos de purificação da vacina contra a febre aftosa. Todos os experimentos foram realizados na empresa Ourofino Saúde Animal. Palavras chave: febre aftosa; proteína 3ABC; anticorpo policlonal anti-3ABC; anticorpo monoclonal anti-3ABC.
Abstract: FMD is a highly contagious disease that affects cloven-hoofed animals and is endemic in Asia, Africa and some countries in South America. In Brazil the epidemiological disease control is achieved by vaccination and health surveillance. For this control is necessary differential diagnosis between vaccinated animals and those carrying the virus, to prove the absence of the disease. Thus it is important to develop tests to differentiate vaccinated animals from sick animals. The antibody response against nonstructural proteins of the virus, have been widely used for this purpose, such as the enzyme-immunoassay ELISA / EITB. The 3ABC is a nonstructural protein of FMD virus and it is present in high levels in infected animals serum. It is necessary to be removed during vaccine production, so the immunized animal does not produce detectable antibodies against them. The aim of this study was to produce and characterize polyclonal and monoclonal antibodies against the 3ABC protein of FMD virus, for their use to develop an enzymatic immunoassay experiments. Such experiments will allows the monitoring of the vaccine purification processes, which removes non-structural proteins and also the quality control process of the produced batches for approval by regulatory agencies such as the Ministry of Agriculture Livestock and Supply (MAPA). In this study, the plasmid to heterologous protein 3ABC production was produced by GONZALEZ, 2013. The expression has been optimized for subsequent production of polyclonal and monoclonal antibodies. For animal's immunization, either rabbit or mouse, the protein used was the semi purified protein. And for the monoclonal antibody screening tests, the protein used was the purified protein. The purification in this stage was due to the need of a specific test to select the monoclonal antibody which is also highly specific. The polyclonal antibody produced in rabbits, showed high titers from 75 days post-immunization. The large amount of polyclonal antibody obtained enabled the using of affinity chromatography using protein G, as a purification method, which resulted in a highly pure immunoglobulin, making it more specific to the protein of interest. For the production of monoclonal antibody (Mabs) BALB/c Mice were immunized intramuscularly. The fusion carried out originated 217 hybridomas colonies, 10 of them were positives for antibody production by ELISA test. After cloning and expansion of positive clones, stability tests were performed wich allowed the selection of two stable clones. The antibodies were characterized by ELISA and Western Blotting approaches. The mabs obteined showed high reactivity against 3ABC protein and as a result they can be used in the development of an ELISA assay to monitor the purification processes of the vaccine against FMD. All experiments were performed in Ourofino Animal Health Company. Key-words: FMD; 3ABC protein; polyclonal anti-3ABC; monoclonal anti-3ABC.
Carvalho, Lincoln Diniz. "Analise das tecnicas GPS atuais para os posicionamentos estaticos e cinematicos em bases curtas." reponame:Repositório Institucional da UFPR, 1999. http://hdl.handle.net/1884/43599.
Dissertação (mestrado) - Universidade Federal do Paraná
Resumo: O objetivo proposto para este trabalho é mostrar, descrever e aplicar as técnicas de posicionamento por GPS explorando um software comercial (PRISM II). Foi utilizado neste, a técnica de posicionamento relativo estático clássico e seus resultados foram comparados com os obtidos pelas técnicas estático rápido com uma ocupação e com reocupação; Stop and Go\ pseudocinemático e cinemático contínuo com diferentes técnicas de inicialização. Estes resultados também foram comparados com os obtidos em levantamentos GPS anteriores, onde utilizou-se apenas a freqüência Li, e com os levantamentos terrestres convencionais. Foram utilizados equipamentos de dupla freqüência; os testes foram realizados em 2 áreas distintas: Centro Politécnico (Curitiba) e Fazenda Cangüiri (Quatro Barras) e em bases curtas. Através da análise dos resultados verificou-se que se pode obter precisão ao nível do milímetro.
Abstract: The objetive of the work developed in this dissertation is to show, describe and apply some GPS positioning techniques, exploring a commercial processing software (PRISM D). The technique of static relative positioning was used first, and its results were compared with the fast static technique, with occupation and with re-ocupation, the Stop and Go technique, with kinematic and kinematic continuous techniques, with different initialization procedures. The results were also compared with previous GPS surveys in which only the Li frequency was used, and with a conventional terrestrial survey. Double frequency receivers were used. The tests were carried out in 2 differente areas: at the Centro Politécnico Campus, in Curitiba, and at Cangüiri Farm, in Quatro Barras. In these two areas only short baselines were used. The analysis of the results shows that an agreement at the millimeter, level is encountered with the static relative positioning.
Magenau, Astrid Irmela Centre for Vascular Research Faculty of Medicine UNSW. "The role of lipid rafts in actin-mediated phagocytosis by macrophages." Publisher:University of New South Wales. Centre for Vascular Research, 2009. http://handle.unsw.edu.au/1959.4/43699.
Xie, Shuiwei Engineering & Information Technology Australian Defence Force Academy UNSW. "Dynamic Contribution-based Decomposition Method and Hybrid Genetic Algorithm for Multidisciplinary Engineering Optimisation." Awarded by:University of New South Wales - Australian Defence Force Academy. Engineering & Information Technology, 2009. http://handle.unsw.edu.au/1959.4/43899.
Bedo, Nicolas. "Connectivity in cortical networks during word reading." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43099.
Moffat, Chandra Elaine. "Cryptic host-associated and frequency-dependent patterns of host species selection of a candidate weed biological control agent in its native range." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43199.
Kushnir, Alexandra Roma Larisa. "An experimental investigation of the mechanical behaviour of synthetic calcite-dolomite composites." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43299.
Lim, Erin. "Technical debt : what software practitioners have to say." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43499.
Thi, Emily Phaps. "Studies in phagosome maturation : modulation by both the host phosphatidylinositol 3-kinase p110alpha and the mycobacterial protein PE-PGRS62." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43699.
McDonald, Morgan. "The US federal courts' deliberate approach : shaping their role in climate reform through procedural tools." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43799.
Tabarraee, Babak. "Silence studies in the cinema and the case of Abbas Kiarostami." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/43899.
Robinson, Kendra Alexis. "Physiological, behavioural and survival effects of assisting the post-capture ventilation of adult sockeye salmon exposed to capture and release in fresh water." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/43999.
Cruzcruz, Angel D. "The strategic shift to the Asia-Pacific." Thesis, Monterey, California: Naval Postgraduate School, 2014. http://hdl.handle.net/10945/43899.
In 2011, President Barack Obama announced that the United States was going to pivot toward the Asia-Pacific. There is widespread scholarly discussion as to whether this shift to the Asia-Pacific was motivated primarily by regional security anxieties or by larger economic and diplomatic interests. Through the analysis of China’s military growth and threatening behavior within the Asia-Pacific region, and the examination of various economic reasons to strategically shift to the Pacific, this thesis attempts to answer the question: Why did the United States decide in 2011 to adopt this rebalancing strategy and increase its military and economic resources to the Asia-Pacific region?
Seipel, Patrick J. "Handheld assistant for military and police patrols." Thesis, Monterey, California: Naval Postgraduate School, 2014. http://hdl.handle.net/10945/43999.
Military and police patrols are an important component of combat operations, counter insurgency, peacekeeping, disaster relief, and humanitarian assistance missions. These patrols need to access timely, relevant information about events and conditions along their patrol route, both historical and ongoing. In the current practice, this information is gathered manually prior to the commencement of the patrol through the use of historical databases, current event repositories, and by reviewing records that may be relevant to the area to be patrolled. Because it is manual, this process is fraught with numerous problems including high-cost, slow-speed, and low-reliability. We present an architecture and a prototype system to enhance the effectiveness and security of patrol units, expedite the planning of patrol missions, and reduce the cost of planning. Our system uses commercial off-the-shelf handheld devices and a web-enabled, device-independent software system that enables planning the patrol route and linking related information to that route. Once the patrol starts, the application tracks the unit’s current location and provides real-time information and alerts about areas of interest along the route. The command post can track the location of all units and deviations from their planned routes are flagged and the command post is alerted.
Jing, Hongyuan. "Landmine detection algorithm design based on data fusion technology." Thesis, University of Leicester, 2018. http://hdl.handle.net/2381/43099.
Braunwart, Paul R. "Uncovering and avoiding failure modes in driveline and tire/wheel NVH using a computational meta-model." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/43099.
Includes bibliographical references (p. 105-110).
The automotive industry has undergone significant changes in recent years with increased competition and the introduction of new manufacturers into the market. With this changing market, a more efficient approach to Noise Vibration and Harshness (NVH) development is needed to foster better decisions and support the compressed product development timing required by the market.To address this, the "Slider Bar" process and meta-model are presented. Based on the failure mode avoidance approach, the process and model allow the engineering teams to uncover and avoid potential tire/wheel and driveline NVH failure modes. Therefore, early in the product development process, development teams can identify control and noise factor limits and system level effects, avoid potential NVH failure modes, and develop appropriate countermeasures.Using insights from innovation diffusion theory, the process and tool were deployed systematically to NVH community, with user insights used to adapt and improve the process and tools. Based on this work, a strategy is introduced for the development and adoption of a failure mode avoidance initiative.
by Paul R. Braunwart.
S.M.
Danziger, Michael (Michael J. ). "Information visualization for the people." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43199.
Includes bibliographical references (p. 85-89).
The design of information visualization, defined as the interactive, graphical presentation of data, is on the verge of a significant paradigm shift brought on by the continued maturation of the Information Age. Its traditional role as a scientific tool deployed by rigorous data analysts is in the process of expanding to include more mainstream uses and users, reflecting fundamental changes to the role of information and data in our increasingly digital society. However, visualization design theory remains rooted in earlier conceptions of its use, largely ignoring the needs of this new, non-expert audience. Accordingly, this thesis attempts to re-contextualize information visualization as a public-facing practice, and explores ways in which its design can shift from being described as "by experts, for experts" to a new characterization as "for the people."
by Michael Danziger.
S.M.
Bishop, Tonja Bowen. "Variation in marginal tax rates around retirement and the return to saving in tax-favored accounts." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43799.
Includes bibliographical references (p. 30-31).
Economists have generally assumed that to the extent possible, retirement savings should be done in a tax-deferred account. However, the advent of Roth-style tax-favored accounts and concerns about the tax implications of increasing retirement income through tax-deferred distributions indicate that this question merits a reevaluation. I use data on married couples in the HRS and NBER's TAXSIM model to measure the probability of a household facing a higher tax rate at ages 62, 65, and 69 than the household faced at age 57. When the marginal tax rate is higher, the household could decrease their lifetime tax by choosing a Roth-style account over a tax-deferred account. I also measure the probability of facing a marginal tax rate that is sufficiently high that the household minimizes tax payments by using a taxable account rather than a tax-deferred account, in the absence of a Roth option. I find that for distributions beginning at age 69, between 10 and 35% of households with taxable income at age 57 should prefer a Roth account to a tax-deferred account, but very few households prefer a taxable account.
by Tonja Bowen Bishop.
S.M.
Gamaliel, Renard. "Frequency-based response of damped outrigger systems for tall buildings." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43899.
Includes bibliographical references (leaf 77).
The outrigger structural system for tall buildings is known to be effective in reducing lateral drift under quasi-static wind loading. Although keeping lateral deflection below the required value is certainly important, it is found that in most tall buildings without supplementary damping, the design for stiffness is usually governed by occupant comfort under lateral acceleration. This thesis describes the concept of incorporating fluid viscous dampers in the outrigger system to add supplementary damping into the structure. A 40-story building installed with the variant outrigger system is analyzed for dynamic response due to wind effects such as buffeting and vortex shedding. By constructing an 80-dof discrete lumped mass model, and using a frequency-based response approach, two configurations of dampers, namely series and parallel damping are studied in detail. The effect of increasing damper size to overall achievable building damping is monitored for both configurations. Additionally, design and constructability issues with regards to the implementation of the systems are discussed.
by Renard Gamaliel.
M.Eng.
Yang, Isabel Y. (Isabel Ying). "Study of sub-0.5 [mega]-m SOI-with-active-substrate (SOIAS) technology for ultra-lower power applications." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/43299.
On t.p. "[mega]" appears as the lower case Greek letter.
Includes bibliographical references (leaves 125-133).
by Isabel Y. Yang.
Ph.D.
Jones, Michael J. (Michael Jeffrey) 1968. "Multidimensional morphable models : a framework for representing and matching object classes." Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/43399.
Includes bibliographical references (p. 129-133).
by Michel Jeffrey Jones.
Ph.D.
Chuang, Erika Shu-Ching. "Design and implementation of a real-time video and graphics scaler." Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/43499.
Includes bibliographical references (leaf 112).
by Erika Shu-Ching Chuang.
M.Eng.
DeBusk, Steven L. "A microcomputer based Energy Monitoring and Reporting System for Virginia state facilities." Thesis, Virginia Tech, 1988. http://hdl.handle.net/10919/43399.
Kulkarni, Nitin Y. "Application of expert systems in landscape architecture." Thesis, Virginia Tech, 1989. http://hdl.handle.net/10919/43899.
Application of artificial intelligence (Al) has been a topic of interest among researchers for the past decade or more. Years of research in the commercial application of Al, availability of hardware support for Al application and affordability of software and hardware has generated a lot of interest in this field and brought this technology within the reach of micro-computer based users. The commercial impact of AI is due to expert systems (ESs). ES technology is a collection of methods and techniques for constructing human-machine systems with specialized problem solving expertise.
This project explores the application of ESs in landscape architecture by developing a prototype ES and testing implications of its use with designers while working on a hypothetical problem in a studio environment. The development process helps identify the typical difficulties of such an application, to uncover technical problems, and to identify areas needing further research.
The project aims at building an ES that provides very limited preliminary data and design guidelines to initialize the design process and keeps track of the most fundamental issues necessary for planning, thus acting as an expert and assistant simultaneously. The idea is to explore the possibility of applying ESs to facilitate the design process so that designers may concentrate on other important aspects of design which include intuitive judgement about qualitative aspects.
Master of Landscape Architecture
Mahalingaiah, Rupaka. "A Comparative study of RISC vs. CISC philosophies of implementing mathematical functions." Thesis, Virginia Tech, 1989. http://hdl.handle.net/10919/43099.
A comparative study of the RISC philosophy of implementing mathematical functions vs the CISC. philosophy implementing the same functions is undertaken. This study tries to verify whether, the RISC philosophy is suited for the computers designed to run specific applications like the realtime systems. A CISC processor is used as a platform machine and several mathematical functions are implemented in both the philosophies.
Master of Science
Woosnam, Kyle Maurice. "Place Attachment as an Interactional Process: A Case Study of Isle au Haut, Maine." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/43599.
Master of Science
Wolford, Gabriela Fernanda. "Failure Initiation and Progression in Internally Pressurized Non-Circular Composite Cylinders." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/43299.
Master of Science
Bertrand, Karine. "La représentation sociale des menstruations : étude exploratoire d'un fragment du corps." Master's thesis, Université Laval, 2003. http://hdl.handle.net/20.500.11794/43099.
Buchacoff, Gustavo Y. (Gustavo Yehezkel). "An active seating system for prevention of pressure sores." Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/43599.
Includes bibliographical references (leaves 64-65).
A pressure management and relief system has been developed for use by wheelchairbound individuals who are at risk of developing pressure sores. This system can be used in passive or active form, depending on an individual's requirement for pressure management and relief. The active seat uses vacuum and pressure in combination with an open-cell-foam-based cushion to perform pressure relief. Testing methods for the system were studied and developed. These methods allow a controlled and precise testing of seating systems. Prototype systems have also been produced and tested. Experimental equipment and data are presented to support performance claims. Prototypes of both active and passive systems have also been tested in a pilot clinical study to assess their effectiveness. Results from this study are presented.
by Gustavo Y. Buhacoff.
S.M.
CERMISONI, ROBERTA. "L'effetto Tau di Vittorio Benussi come modello di studio del presente fenomenico: nuove prospettive di ricerca per l'esame della percezione del tempo e della personalità." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2013. http://hdl.handle.net/10281/43699.
Plasencia, Castillo Carmen. "Actividad in vitro de Oxaliplatino asociado a otros fármacos y demostración de la reversión de la resistencia a 5-Fluorouracilo." Doctoral thesis, Universitat Autònoma de Barcelona, 2002. http://hdl.handle.net/10803/4399.
El Oxaliplatino y los inhibidores de Topoisomerasa I (TPT y CPT-11) son agentes citotóxicos con actividad antitumoral en el CCR. En el presente estudio, también se evaluó la citotoxicidad de las asociaciones entre OXA y 5-FU o TPT en un panel de líneas celulares derivadas de tumores colorrectales sensibles (HT29, LoVo, DLD-1 y LS-513) y resistentes a 5-FU (HT29-5FUR y LoVo-5FUR). Asimismo se analizó la expresión de TS (ARNm y proteína) y Topoisomerasa I (Topo I; ARNm) tras la exposición a OXA como parámetros directamente relacionados con la sensibilidad al 5-FU e inhibidores de Topo I respectivamente, en las parejas sensibles/resistentes. Los esquemas secuenciales analizados fueron: OXA(4h)®5-FU(24h); 5-FU(24h)®OXA(4h); OXA(4h)®TPT(24h); TPT(24h)®OXA(4h) y OXA(4h)®5-FU (5 días a las dosis a las que se indujo la resistencia en las parejas sensible/resistente). Todas las combinaciones resultaron sinérgicas a dosis moderadas de ambos fármacos, únicamente la asociación 5-FU®OXA en la línea LoVo-5FUR resultó aditiva para cualquier fracción de inhibición. La sinergia fue además independiente del fenotipo de resistencia a 5-FU, del estado del sistema reparador del ADN y/o del estado de p53. La exposición previa a OXA en los esquemas OXA®5-FU y OXA®TPT permitió reducir las dosis de 5-FU y TPT en combinación en las líneas resistentes hasta niveles similares a los requeridos por las correspondientes líneas sensibles, revirtiendo el fenotipo de resistencia a 5-FU y permitiendo en el caso de la línea LoVo-5FUR sobrepasar el fenotipo de resistencia cruzada a Inhibidores de Topo I. La exposición a OXA, administrado como agente único provoca una caída de los niveles de TS (ARNm y proteína) en todas las líneas celulares analizadas. Durante la exposición a 5-FU se observó una sobreexpresión de los niveles de TS en todas las líneas celulares, aunque este incremento fue mucho menor en el esquema OXA®5-FU (entre 3 y 5 veces) comparado con el obtenido para la exposición a 5-FU como agente único. Estos resultados correlacionaron con la actividad sinérgica observada para la asociación OXA®5-FU. La exposición previa a OXA también indujo una disminución en los niveles de expresión de Topo I que correlacionó con la disminución en la dosis de TPT en la combinación OXA®TPT. Estos resultados también sugieren que la administración de los inhibidores de Topo I debe ser previa al OXA ya que los niveles disminuidos de Topo I es uno de los principales mecanismos de resistencia a este tipo de fármacos. Finalmente demostramos que la citotoxicidad observada en las asociaciones entre OXA y 5-FU no correlaciona con un incremento en los procesos apoptóticos. En conclusión, el presente estudio in vitro permite ampliar el conocimiento de las bases moleculares de la actividad de las asociaciones de 5-FU e inhibidores de Topo I y derivados platinados. La disminución en los niveles de TS tras la exposición a OXA en el esquema OXA/5-FU proporciona una nueva interpretación al sinergismo observado en esta asociación tanto en tumores sensibles como resistentes a 5-FU. Por otro lado, la combinación OXA/Inhibidores de Topo I representa una alternativa para el tratamiento del CCR avanzado.
Over more than 40 years, 5-Fluorouracil-based chemotherapy has been the standard treatment of colorectal cancer (CRC). Chemotherapy resistance is an important cause of cancer treatment failure. 5-Fluorouracil (5-FU) inhibits Thymidylate Synthase (TS) enzyme. Overexpression of Thymidylate Synthase (TS) has been correlated to 5-FU-resistance Several studies have also indicated that 5-FU resistance may be due to a multiple genetic pathways which includes transport mechanisms, metabolism, molecular mechanism, cell cycle kinetics and protection from apoptosis. At the present work, two 5-FU-resistant cell lines (HT29-5FUR and LoVo-5FUR) were established from sensitive parental cell lines (HT29 and LoVo, respectively) by stepwise with increasing concentrations of 5-FU. Cell cycle distributions and doubling times were barely equivalent in both, sensitive and 5-FU-resistant cell lines. 5FU-resistant cell lines exhibit about a 5-fold and 3-fold increase in resistance to the drug as compared to parental cell lines. No differences in sensitivity towards Oxaliplatin were found between sensitive/5-FU-resistant cells. Interestingly, LoVo-5FUR cell line show a cross-resistance pattern to Topoisomerase I inhibitors (TPT, CPT-11 and SN38). 5-FU adaptation does not alter p53 status or RER phenotype in these cell lines. Cellular resistance to 5-FU correlated with an increase in TS gene expression (ARNm and protein), although no gene amplification was observed. Comparative genomic hybridisation (CGH) analysis revealed several genetic abnormalities (gains/loss) in 5-FU-resistant cells as compared to corresponding parental cell lines that could be potentially related with 5-FU resistance phenotype.
Oxaliplatin (OXA) and DNA Topoisomerase I inhibitors (TPT, CPT-11) are cytotoxic agents with proven clinical antitumor activity in CRC. At the present work, we also studied the cellular pharmacology of OXA in combination with 5-FU or TPT in a panel of sensitive (HT29, LoVo, DLD-1 and LS-513) and 5-FU-resistant human colon cancer cells (HT29-5FUR and LoVo-5FUR). Moreover, we evaluated TS (mRNA and protein) and Topoisomerase I (Topo I; mRNA) expression after OXA exposure as parameters directly related to sensitivity to 5-FU and Topo I inhibitors respectively, in sensitive/resistant cell lines. Sequential combination schedules used were: OXA(4h)®5-FU(24h); 5-FU(24h)®OXA(4h); OXA(4h)®TPT(24h); TPT(24h)®OXA(4h) and OXA(4h)®5-FU(5-days exposure at the 5FU dose used for the induction of 5FU-resistance phenotype). All sequential associations were synergistic at moderate doses of both drugs in all cell lines tested, only 5-FU®OXA combination was additive in LoVo-5FUR cells to all inhibition fraction. The synergism found was independent from 5-FU-resistant phenotype, mismatch repair system or p53 status. Previous exposure to OXA in OXA®5-FU and OXA®TPT schedules reduced doses of 5FU and TPT given in combination at the resistant cell lines until levels similar to that obtained in corresponding sensitive cell lines suggesting the role of Oxaliplatin in the overcoming of 5-FU resistance phenotype and in the abrogation of the cross-resistance pattern to Topo I inhibitors showed by LoVo-5FUR cells. The exposure to OXA as single agent induced a significant decrease in TS levels (mRNA and protein) in all cell lines. We have also observed that sequential administration of OXA/5-FU induced a significant decrease in TS mRNA expression (between 3 and 5-fold) as compared to exposure to 5-FU as a single agent in both, sensitive and 5FU-resistant cell lines. These results correlated with the synergistic activity observed in sequential OXA/5-FU administration schedule. Previous exposure to OXA also induced a down-regulation of Topo I gene expression that correlates with the decrease of TPT doses in OXA®TPT combination schedule. These results also suggest that Topo I inhibitors should to be administered previous to OXA, as diminished Topo I levels is one of the most important cause of resistance to these agents. Finally, we demonstrated that despite the high level of cytotoxicity found in the associations between OXA and 5-FU, no increases in apoptosis were observed. In conclusion, our in vitro findings contribute to a better knowledge of the combination of 5-FU or Topo I inhibitors and platinum derivatives, contributing to a rationale for the optimal clinical development of the association between these agents. Down-regulation of TS due to OXA exposure in OXA/5-FU schedules promote a new interpretation of the synergistic activity observed in sensitive and 5-FU-refractory tumours. By other hand, combination of OXA/Topoisomerase I inhibitors represent an alternative for the treatment of advanced colorectal cancer.
Hemphill, Susan Patricia. "Effect of sorghum bran addition on lipid oxidation and sensory properties of ground beef patties differing in fat levels." Texas A&M University, 2006. http://hdl.handle.net/1969.1/4399.
Lam, Jennifer Eleanor. "The nature of the metal-insulator transition in silicon germanide quantum wells." Thesis, University of Ottawa (Canada), 1997. http://hdl.handle.net/10393/4399.
Courtney, Karen Lynne. "Privacy and senior adoption of assistive technology in residential care." Diss., Columbia, Mo. : University of Missouri-Columbia, 2006. http://hdl.handle.net/10355/4399.
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Vita. "May 2006" Includes bibliographical references.
Hickman, Cristina Fontes Lindemann. "Environmental factors affecting interferon-τ expression and secretion by in vitro produced bovine blastocysts". Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4399.
Schoen, Steven W. "The Rhetoric of Evidence in Recent Documentary Film and Video." Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4399.
Kotzé, Hester Johanna. "Evaluation of specific genotypes in the context of the type 2 diabetes risk phenotype in the black South African population / by H.J. Kotzé." Thesis, North-West University, 2010. http://hdl.handle.net/10394/4399.
Thesis (Ph.D. (Biochemistry))--North-West University, Potchefstroom Campus, 2010.
Xu, Yang. "Business rules based legacy system evolution towards service-oriented architecture." Thesis, De Montfort University, 2010. http://hdl.handle.net/2086/4399.
Rautenbach, Karel Frederick. "Characterisation of a solar roof tile (SunSlates™) : with focus on local applicability and conditions." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/4399.
Thesis (MScEng (Mechanical and Mechatronic Engineering))--Stellenbosch University, 2008.
Three SunSlates™ were investigated to predict the performance of a fully installed system. The three slates were mounted on a fixed tilt of 30°, but with different orientations. The tilt is close to latitude of the Stellenbosch site, which is 33.92°. The one faces due east, another due west and last due north. This is to determine the effect that orientation has on the energy from the SunSlates™. Another slate, also facing north, was mounted on an adjustable framework. The framework was used to adjust the tilt angle of the slate, the orientation of the slate was constantly north. This slate was used to determine the effect of tilt on the total daily energy produced by the slate. To determine the performance of the slates daily measurements of temperature, solar insolation and wind was taken. These were used to investigate the effects on the SunSlates™. During the test period, which scheduled from September to November, the results show a difference, smaller than commonly believed, in the daily and annual energy delivered from the differently orientated slates. The slates facing east and west, however, have similar energy outputs, even though the power profiles differ. The north facing slate has the highest annual energy output, as expected. It was found that during the months of summer, November to January, the optimal tilted slate (Slate tilted to have a incidence angle of 0° from solar rays at noon) had a slightly lower energy output, but higher maximum power output per day than the 30 degree tilted slate. This is in contrast to the energy output predictions for the winter months where in the winter the energy can be as much as double that of the 30 degree tilted slate. The thorough testing and expert installation of the SunSlates™ are essential. From the case study it can be seen that some problems during installation, possibly a single faulty slate or shadowing, can cause a complete system to lose 30% of its efficiency.
Centre for Renewable and Sustainable Energy Studies
Silva, Maria Margarida de Aguiar Martins da. "Plano regional de emergência externa no âmbito da saúde." Master's thesis, [s.n.], 2014. http://hdl.handle.net/10284/4399.
A eficácia da ação dos serviços de saúde em situações de emergência ou de catástrofe de grande dimensão é um tema do maior interesse para os todos os profissionais ligados à área da saúde. Por outro lado, e no caso de catástrofes com significativo número de vítimas, as questões de identificação humana ou médico-legal enfatizam o papel da medicina dentária forense nestas situações. Foi propósito deste trabalho avaliar da existência de planos regionais de emergência externa no âmbito da saúde integrados num campo mais vasto do sistema nacional de proteção civil. Após identificação do quadro legal aplicável e da determinação das entidades a nível nacional, regional, ou local com competências nesta matéria, foi elaborado um inquérito que, posteriormente, foi enviado a essas entidades. Procedeu-se também a um conjunto de entrevistas a profissionais de saúde especialistas nestas matérias. Os resultados das diligências realizadas e das respostas ao inquérito elaborado permitiram concluir da existência de notórias diferenças de entendimento das situações por parte das autoridades numa esfera nacional, quer de proteção civil quer na área da saúde. Verificou-se também um assinalável consenso entre especialistas ligados à saúde quanto à não existência de planos regionais de emergência externa no âmbito da saúde e à urgência na sua elaboração e aplicação. Como resultado, é sugerida a elaboração destes planos aplicáveis a todas as unidades de saúde de cada região, dos quais resulta a otimização do pessoal e dos meios existentes. Propõe-se ainda a inclusão de profissionais de medicina dentária nas equipas multidisciplinares que operam em situação de emergência. Effectiveness of the action of health services in emergencies or mass disasters must be a major concern for all the health professionals. Also, in case of mass disasters with a significant number of casualties, the role of the forensic odontology in those situations is essential for identification of the victims. This investigation aims to evaluate the existence of a Regional Plan for External Emergency, in the field of the health services within the scope of the national system of civil protection. After the determination of the applicable legal frame and the identification of the competent national, regional or local authorities, an enquiry was elaborated and sent to these authorities. Also, a number of direct enquiries to some specialised health professional were held. The results observed after the analysis of the answers to the enquiry led to conclude about the existence of significant differences on the understanding of the whole situation by the national authorities of civil protection and health services. It was also established a significant consensus among the health specialists on the nonexistence of any regional plan for external emergency in the field of health services and on the urgent need of its effective existence. As a result of this investigation it is suggested the creation of these regional plans involving all the health units in each region, aiming to optimise the performance of the existent personnel and facilities. Finally it is suggested the inclusion of odontology professionals in the multidisciplinary teams operating in emergency situations.