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Статті в журналах з теми "342.475 6":
1
Vashchyshyn, Oksana, Halyna Bilovus, Antin Shuvar, and Hanna Dorota. "Anthracnose of flax in conditions of Western Forestr of Ukraine." Bast and Technical Crops, no. 6(11) (December 1, 2018): 92–98. http://dx.doi.org/10.48096/btc.2018.6(11).92-98.
Анотація:
The results of the study of the dynamics of the development and spread of flax anthracnosis in the conditions of the western forest-steppe of Ukraine are presented. The influence of the stability of the variety and the abiotic factors on the damage of plants by the disease is established. It is studied and recommended for use in the breeding process as a starting material for creating resistant varieties for anthracnose: varieties Mogilevsky-2, Slavny, Taurneus B-35, Krisstall, Nike, K-6, Kievsky-2, Verin, Lintex, Milenium, Daros I, T. Tammes st 19, Arsen, Achay and hybrids 2527, AL-340, C-332, 405/4, № 340, 403/6.
2
Karuturi, Meghan S., Gabrielle B. Rocque, Joseph C. Cappelleri, Joanne L. Blum, Steven L. McCune, Bijoy Telivala, Sobha Kurian, et al. "Abstract P1-18-25: Real-world quality of life (QoL) in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-), advanced breast cancer (ABC) treated with palbociclib: A patient-reported outcome (PRO) analysis from POLARIS." Cancer Research 82, no. 4_Supplement (February 15, 2022): P1–18–25—P1–18–25. http://dx.doi.org/10.1158/1538-7445.sabcs21-p1-18-25.
Анотація:
Abstract Background: POLARIS is an ongoing, prospective, real-world, noninterventional, multicenter study in patients with HR+/HER2- ABC receiving palbociclib in the United States and Canada. This report describes PRO data from a real-world setting of patients with ABC receiving palbociclib. Methods: POLARIS has a targeted enrollment of 1500 patients from ~110 sites in the United States and Canada. Key inclusion criteria included patients with HR+/HER2- ABC with evidence of metastatic disease. QoL was assessed with the European Organisation for Research and Treatment of Cancer Quality-of-Life Questionnaire Core 30 (EORTC QLQ-C30). A clinical problem threshold for 5 functioning and 9 symptom scales of the EORTC QLQ-C30 was established with anchor questions assigned for each domain to assess functional health and symptom burden. Results: As of March 16, 2021, 1240 patients were treated with palbociclib and had EORTC QLQ-C30 data collected and analyzed (at baseline, n=1240; after 6 months of palbociclib treatment, n=1076; after 12 months of palbociclib treatment, n=926). At baseline, the median age of patients was 64 years (Table 1). The majority of patients were white (82%) and 98.8% were female. Nearly 95% of patients had stage 4 metastatic disease, 5.1% had locally advanced stage (III), 68% had a recurrent disease from the earlier stage (0-III), and 27.3% had de novo stage IV disease diagnosed at enrollment. In this cohort, 98.3% of patients were estrogen receptor-positive (ER+)/progesterone receptor-positive (PR+), 94% were HER2-, with 99% of patients HER2- also ER+/PR+ at or nearest to the enrollment date. The percentages of patients with functioning scale scores (physical [baseline=54.6%; month 6=50.2%; month 12=50.4%], role [baseline=28.6%; month 6=20.1%; month 12=18.6%], social [baseline=24.2%; month 6=15%; month 12=15%], emotional [baseline=37.1%; month 6=29.6%; month 12=29.4%], and cognitive [baseline=34.2%; month 6=34.5%; month 12=31.7%]) below the clinical problem threshold remained stable over the first 12 months of palbociclib treatment (Table 2). A similar trend across time was observed with the symptom scales with the percentages of patients (fatigue, pain, nausea and vomiting, insomnia, appetite loss, constipation, dyspnea, diarrhea, and financial difficulties) above the clinical problem threshold also remaining stable over the first 12 months (Table 2). Conclusions: In this PRO analysis, palbociclib treatment did not have any significant adverse impact on QoL in patients with HR+/HER2- ABC as assessed by QLQ-C30 functioning and symptom scales. Pfizer (NCT03280303) Table 1.Patient Demographic CharacteristicsCharacteristicTotal. (N=1240)Age at study enrollmentMedian (range), y64 (22-97)Distribution, n (%)<40 y61 (4.9)40 to 50 y144 (11.6)51 to 69 y622 (50.2)70 to 74 y181 (14.6)75 to 84 y198 (16.0)≥85 y34 (2.7)Sex, n (%)Male15 (1.2)Female1225 (98.8)Race, n (%)American Indian or Alaska Nativea8 (0.6)Asian19 (1.5)Black or African Americana138 (11.1)Native Hawaiian or other Pacific Islandera5 (0.4)White1017 (82.0)Not reported due to confidentiality regulations27 (2.2)Other23 (1.9)Not reported3 (0.2)Ethnicity, n (%)Hispanic or Latinob104 (8.4)Not Hispanic or Latino1099 (88.6)Not reported due to confidentiality regulations36 (2.9)Time from ABC/mBC diagnosis date to study enrollment dateMedian (range), y1.35 (0-248)Missing, n7Distribution, n (%)≤1 mo508 (41.0)>1 to 2 mo247 (19.9)>2 to 3 mo71 (5.7)>3 to 4 mo22 (1.8)>4 to 5 mo23 (1.9)>5 to 6 mo12 (1.0)>6 mo350 (28.2)aMinority. bMinority among White. ABC=advanced breast cancer; mBC=metastatic breast cancer. Table 2.Percentages of Symptoms and Functional ImprovementScaleClinical problem (threshold)Baselinea n (%)Month 6a n (%)Month 12a n (%)Functioning ScalesbPhysical functioningc<83629 (54.6)365 (50.2)239 (50.4)Mean (SD)73.3 (24.8)76.9 (22.2)76.7 (21.7)Role functioningc<58330 (28.6)146 (20.1)88 (18.6)Mean (SD)70.4 (32.7)76.0 (27.8)77.2 (26.6)Social functioningd<58278 (24.2)109 (15.0)71 (15.0)Mean (SD)74.4 (29.8)80.7 (25.0)81.0 (25.3)Emotional functioninge<71427 (37.1)215 (29.6)139 (29.4)Mean (SD)74.3 (23.1)79.6 (20.4)80.5 (21.0)Cognitive functioninge<75394 (34.2)251 (34.5)150 (31.7)Mean (SD)78.9 (24.4)80.4 (21.3)80.7 (22.9)Symptom ScalesbFatiguec>39421 (36.5)256 (35.2)144 (30.4)Mean (SD)36.7 (26.9)34.2 (23.0)33.0(24.4)Painc>25614 (53.3)341 (46.9)221 (46.6)Mean (SD)34.8 (31.7)26.7 (26.4)26.6 (27.2)Nausea and vomitingc>8423 (36.7)233 (32.0)153 (32.3)Mean (SD)12.4 (21.2)9.4 (17.4)9.7 (17.3)Insomniaf>50279 (24.2)156 (21.5)89 (18.8)Mean (SD)31.7 (31.1)29.3 (28.9)26.8 (29.0)Appetite lossf>50205 (17.8)72 (9.9)48 (10.1)Mean (SD)23.3 (30.2)16.9 (25.0)15.9 (25.2)Constipationc>50142 (12.3)71 (9.8)46 (9.7)Mean (SD)18.9 (27.6)15.7 (23.7)15.3 (23.8)Dyspneag>17547 (47.6)323 (44.5)207 (43.7)Mean (SD)23.0 (28.8)19.1 (24.8)18.5 (24.5)Diarrheah>17327 (28.5)209 (28.7)120 (25.4)Mean (SD)12.9 (23.5)12.8 (22.6)10.5 (20.1)Financial Impact of Diseasei>17563 (49.0)322 (44.3)198 (42.0)Mean (SD)26.9 (33.2)22.5 (30.3)20.2 (27.9)aThe number of patients eligible at a visit is based on data expected to be available through the latest date of exposure, visit date, or questionnaire date. Baseline, N=1240; Month 6, N=1076; Month 12, N=926. bPercentages for functional and symptom scales were calculated based on “n,” the number of measurements available. Values for Mean (Standard Deviation, SD) were also based on “n”. cn (missing), Baseline=1152 (88); Month 6=727 (349); Month 12=474 (452) dn (missing), Baseline=1151 (89); Month 6=726 (350); Month 12=473 (453) en (missing), Baseline=1151 (89); Month 6=727 (349); Month 12=473 (453) fn (missing), Baseline=1151 (89); Month 6=727 (349); Month 12=474 (452) gn (missing), Baseline=1149 (91); Month 6=726 (350); Month 12=474 (452) hn (missing), Baseline=1149 (91); Month 6=727 (349); Month 12=473 (453) in (missing), Baseline=1149 (91); Month 6=727 (349); Month 12=471 (455) Note: For functioning scales, scoring below the clinical problem threshold indicates a clinically important problem whereas, for the symptom scales, scores above the clinical problem threshold indicate such a problem. Citation Format: Meghan S. Karuturi, Gabrielle B. Rocque, Joseph C. Cappelleri, Joanne L. Blum, Steven L. McCune, Bijoy Telivala, Sobha Kurian, Daniel M. Anderson, Michaela Tsai, Timothy Pluard, John Migas, Yao Wang, Monica Z. Montelongo, Debu Tripathy. Real-world quality of life (QoL) in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-), advanced breast cancer (ABC) treated with palbociclib: A patient-reported outcome (PRO) analysis from POLARIS [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P1-18-25.
3
Černý, Karel. "Hugh Wilford: America’s Great Game: The CIA’s Secret Arabists and the Shaping of the Modern Middle East." Czech Journal of International Relations 50, no. 4 (December 1, 2015): 72–76. http://dx.doi.org/10.32422/cjir.250.
4
Min, Wang Kee, Sung Doo Hwang, Chang Ho Lee, Young Do Park, Yong Ho Park, and Ik Min Park. "Influence of Thermo-Mechanical Heat Treatment on the Thermoelectric Properties of Ag Added Bi1Sb3Te6 Compounds." Solid State Phenomena 118 (December 2006): 47–52. http://dx.doi.org/10.4028/www.scientific.net/ssp.118.47.
Анотація:
The direct extrusion process using the mechanically alloyed powder as raw materials was applied to prepare the thermoelectric materials. The mechanically alloyed powders of Ag added Bi1Sb3Te6 were extruded using pulse discharge sintering method at temperatures ranging from 345°C to 425°C. The fractographs of extruded specimens shows that no grain size changes was observed until 385°C, but became coarser with the increase of the extrusion temperature above 405°C. The X-ray diffraction patterns showed that the intensity of (110) plane increased with extrusion temperature up to 385°C and started to drop down above 405°C. The power factor value (PF) also increased with the extrusion temperature up to 385°C and altered above 405°C. These trends agreed with the variation in intensity of (110) plane of XRD patterns. The figure of merit (Z) value of the extruded specimens at 385°C was 3.1 × 10-3 W/K, which was the highest value among the prepared specimens.
5
Gaywood, Alexander P., and Hamish McNab. "Synthesis and Chemistry of 4,5-Dihydrothieno[3,2-b]pyrrol-6-one—A Heteroindoxyl." Journal of Organic Chemistry 74, no. 11 (June 5, 2009): 4278–82. http://dx.doi.org/10.1021/jo900496u.
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Abdel-Hafez, Shams H., Ragaa A. Ahmed, Mohamed A. Abdel-Azim, and Khairy M. Hassan. "Selenium containing Heterocycles: Part 1. Synthesis of Some New Substituted Pyrido[3′,2′:4,5]selenolo[3,2-d]pyrimidines and Related Fused Tetracyclic Systems." Journal of Chemical Research 2007, no. 10 (October 2007): 580–84. http://dx.doi.org/10.3184/030823407x25506.
Анотація:
New series of selenolo[2,3- b]pyridine, pyrido[3′,2′:4,5]selenolo[3,2- d]pyrimidine, 7,8-dihydro-2,4-dimethylpyrrolo [1,2- a]pyrido[3′,2′:4,5]selenolo[3,2- d]pyrimidin-10(6 H)-one and 7,9-dimethylpyrido[3′,2′:4,5]selenolo[3,2- d][1,2,4] triazolo[4,3- c]pyrimidine derivatives were synthesised from 3-cyano-4,6-dimethylpyridine-2(1 H)-selenone (1). Spectroscopic (IR, 1H, MS) of the newly synthesised compounds are reported.
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Izmest’ev, Alexei N., Galina A. Gazieva, Natalya V. Sigay, Sergei A. Serkov, Valentina A. Karnoukhova, Vadim V. Kachala, Alexander S. Shashkov, Igor E. Zanin, Angelina N. Kravchenko, and Nina N. Makhova. "An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy." Beilstein Journal of Organic Chemistry 12 (October 24, 2016): 2240–49. http://dx.doi.org/10.3762/bjoc.12.216.
Анотація:
An effective and highly regio- and diastereoselective one-pot method for the synthesis of new polynuclear dispiroheterocyclic systems with five stereogenic centers (dispiro[imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-6,3′-pyrrolidine-2′,3′′-indoles]) comprising pyrrolidinyloxindole and imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine moieties has been developed. The method relies on a 1,3-dipolar cycloaddition of azomethine ylides generated in situ from isatin derivatives and sarcosine to 6-benzylideneimidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-2,7-diones.
8
Komyakov, Boris K., Anton E. Saad, Vladimir A. Fadeev, Talat H. Al-Attar, and Aleksey V. Sergeev. "Local recurrences after radical cystectomy in bladder cancer patients." Urology reports (St. - Petersburg) 12, no. 4 (January 22, 2023): 269–76. http://dx.doi.org/10.17816/uroved112087.
Анотація:
BACKGROUND: Radical cystectomy is the standard treatment for patients with muscle-invasive bladder cancer and superficial neoplasms in cases of resistance to intravesical immunochemotherapy.
AIM: To establish the frequency of local pelvic recurrence in patients with bladder cancer after radical cystectomy.
MATERIALS AND METHODS: From 1997 to 2022 radical cystectomy was performed in 407 patients with bladder cancer: 344 (84.5%) men and 63 (15.5%) women. Orthotopic urinary diversion methods were performed in 302 (74.2%) patients, including gastrocystoplasty 24 (5.9%), ileocystoplasty 253 (63.8%) and sigmocystoplasty 25 (6.1%) patients. Continent skin diversion of urine was performed in 13 (3.2%) patients, ureter transplantation into the sigmoid colon in 42 (10.3%) patients, and ureterocutaneostomy in 50 (12.3%) patients.
RESULTS: Local recurrence in the pelvis after radical cystectomy was observed in 33 (8.1%) patients: 27 (81.8%) men and 6 (18.2%) women. The average age of men with relapses was 58.7 11.7 years (from 43 to 73 years), women 50.0 7.8 years (from 24 to 65 years). Simultaneous metastatic lesions of internal organs were detected in 6 (18.2%) patients. Local pelvic recurrence after radical cystectomy occurred more often in lymphopositive patients with extravesical spread of the primary low-grade tumor. The median time from radical cystectomy to detection of pelvic recurrence was 7.0 months, from the moment of detection of pelvic recurrence to the death of the patient 4.5 months.
CONCLUSIONS: The frequency of local pelvic recurrence of bladder cancer after radical cystectomy is 8.1%. The survival rate of patients with local pelvic recurrence is extremely low.
9
Kraľovičová, Eva, Alžbeta Krutošíková, and Jaroslav Kováč. "Preparation and reactions of thieno[3,2-b]furan derivatives." Collection of Czechoslovak Chemical Communications 51, no. 8 (1986): 1685–91. http://dx.doi.org/10.1135/cccc19861685.
Анотація:
Reactions of 3-(5-aryl-2-furyl)propenoic, 3-(2-benzo[b]furyl)propenoic and 3-(5-ethoxycarbonyl-4H-furo[3,2-b]-2-pyrrolyl)propenoic acids with thionyl chloride in the presence of triethylbenzylammonium chloride were investigated. The obtained 2-arylthieno[3,2-b]-furan-5-carboxylic acid chlorides Ia - Ic and 3-chlorothieno[3,2-b]benzo[b]furan-2-carboxylic acid chloride afforded in substitution nucleophilic reactions the corresponding esters V and carboxylic acids VI which were decarboxylated to VII. 3-Chlorothieno[3,2-b]benzo[b]furan-2-carboxylic acid chloride (Id), 6-ethoxycarbonyl-3-chlorothieno[2',3':4,5]furo[3,2-b]pyrrole-2-carboxylic acid chloride (IV), and ethyl 3-chlorothieno[2',3':4,5]furo[3,2-b]indole-2-carboxylate (VIII), synthesized under conditions of triethylphosphite reduction from ethyl 6-chloro-2-(2-nitrophenyl)thieno[3,2-b]furan-5-carboxylate (Va), are new heterocyclic systems.
10
Deeb, Ali, Besher Bayoumy, Fathy Yasine, and Rida Fikry. "Pyridazine Derivatives and Related Compounds, Part 4. Pyrrolo[2,3-c]pyridazines and Furo[2,3-c]pyndazines, Synthesis and Some Reactions." Zeitschrift für Naturforschung B 47, no. 3 (March 1, 1992): 418–23. http://dx.doi.org/10.1515/znb-1992-0320.
Анотація:
Ethyl 5-amino-3,4-diphenyl-7H-pyrrolo[2,3-c]pyridazine-6-carboxylate (1), ethyl 5-aminofuro[ 2,3-c]pyridazine-6-carboxylate (2) and 5-aminofuro[2,3-c]pyridazine-6-carboxamide (3), are obtained from 4-cyano-5,6-diphenyl-3(2H)-pyridazinone. 5-Acetamido and 5-chloroacetamido derivatives prepared from 1, undergo cyclization on heating to form 2-substituted pyridazino[4',3':4,5]pyrrolo[3,2-d]oxazin-4(5H)-one (5a, b). The reaction of 1 and 2 with hydrazine gave 6-carbohydrazide derivatives (7 a, b). Compound 3 undergoes condensation with acetyl chloride, chloroacetyl chloride, benzoyl chloride, formamide and carbon disulphide to furnish the corresponding pyrimido[4',5' :4,5]furo[2,3-c]pyridazin-4(3 H)-one derivatives. The reaction of 1 with o-aminophenol gave 3,4-diphenyl-11-oxo-10,11-dihydro-12H -pyridazino[ 4',3' :4,5]pyrrolo[3,2-b][1,5]benzoxazepine.
Дисертації з теми "342.475 6":
1
Chien, Ching-Ming, and 簡啟民. "Cytotoxic mechanisms of Cardiotoxin III (CTX III)、N′-(11H-indolo[3,2-c]quinolin-6-yl)-N,N-dimethylethane-1,2-diamine (IQDMA) and Naphtho[1,2-b]furan-4,5-dione (NFD)." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/85029628380595944153.
Анотація:
博士高雄醫學大學
醫藥暨應用化學研究所
98
Apoptosis plays an important role in the regulation of cellular activities in eukaryotes. Three predominant apoptotic pathways are the mitochondria-mediated intrinsic pathway, the death receptor-induced extrinsic pathway and apoptotic signalling evoked by endoplasmic reticulum (ER) stress. Three type of compounds (CTX III, IQDMA and NFD)-induced apoptotic cell death accompanied by regulation of Bcl-2 family, loss of mitochondrial membrane potential, release of cytochrome c and caspase-9, -3 activation. In addition, CTX III induced ER stress, release of Ca2+ ion, activation of calpain and caspase-12. Finally, cell death caused by both mtiochridal and ER stress dependent apoptosis. Cell cycle control is the major regulatory mechanism of cell growth. Many cytotoxic agents and/or DNA damaging agents arrest the cell cycle at the G1, S or G2/M phase and then induce apoptotic cell death. CTX III resulted in S phase arrest in the cell cycle progression, which was associated with a marked decrease expressions of cyclin A, cyclin B1, and CDK 1. Mitogen-activated protein kinase (MAPK) members have been identified as an important signaling in the control of cell proliferation and differentiation. The activation of JNK played an important role in CTX III induced apoptosis. Signal transducer and activator of transcription (STAT) proteins have been shown to have a major role in survival, proliferation, angiogenesis, and immune evasion of tumors. Inhibitions of phosphorylation of STAT3 and STAT5 with CTX III treatment and of STAT5 with IQDMA treatment regulated the downstream effects and linked to anti-proliferation. Tyrosine kinases, classified into receptor tyrosine kinases and non receptor kinases, play important role in regulation of cell proliferation, differentiation, survival, and carcinogenesis. CTX III inhibited phosphorylation of Src and then phosphorylation of EGFR at Y845 site, subsequently, cell cycle arrested at S phase. IQDMA abolished Src and STAT5 activation, later induced apoptosis. NFD treatment inactivated EGFR and PI3K/Akt pathway, leading to apoptotic death. Collectively, the study used three types of compounds for apoptosis and cell cycle arrest. These results provide the impetus for developing new therapeutic strategies in which synthetic compounds.
Книги з теми "342.475 6":
1
Good, Phillip I. Resampling Methods. Boston, MA: Birkhäuser Boston, 2001. http://dx.doi.org/10.1007/978-1-4757-3425-6.
2
Алгебра: підруч. для 7 кл. закладів заг. серед. освіти. Харків, Україна: Гімназія, 2020.
3
Gilmore, Stephen, and Lisa Glennon. Hayes & Williams' Family Law. Oxford University Press, 2018. http://dx.doi.org/10.1093/he/9780198811862.001.0001.
Анотація:
Hayes and Williams’ Family Law, now in its sixth edition, provides critical and case-focused discussion of the key legislation and debates affecting adults and children. The volume takes a critical approach to the subject and includes ‘talking points’ and focused ‘discussion questions’ throughout each chapter which highlight areas of debate or controversy. The introductory chapter within this edition provides a discussion of the law’s understanding of ‘family’ and the extent to which this has changed over time, a detailed overview of the meaning of private and family life within Article 8 of the ECHR, and a discussion of the Family Justice Review and subsequent developments. Part 1 of this edition, supplemented by the ‘Latest Developments’ section, outlines the most up-to-date statistics on the incidence of marriage, civil partnerships and divorce, discusses recent case law on the validity of marriage such as Hayatleh v Mofdy [2017] EWCA Civ 70 and K v K (Nullity: Bigamous Marriage) [2016] EWHC 3380 (Fam), and highlights the recent Supreme Court decision (In the Matter of an Application by Denise Brewster for Judicial Review (Northern Ireland) [2017] 1 WLR 519) on the pension rights of unmarried cohabitants. It also considers the litigation concerning the prohibition of opposite-sex civil partnership registration from the judgment of the Court of Appeal in Steinfeld and Keidan v Secretary of State for Education [2017] EWCA Civ 81 to the important decision of the Supreme Court in R (on the application of Steinfeld and Keidan) (Application) v Secretary of State for International Development (in substitution for the Home Secretary and the Education Secretary) [2018] UKSC 32. This edition also provides an in-depth discussion of the recent Supreme Court decision in Owens v Owens [2018] UKSC 41 regarding the grounds for divorce and includes discussion of Thakkar v Thakkar [2016] EWHC 2488 (Fam) on the divorce procedure. Further, this edition also considers the flurry of cases in the area of financial provision on divorce such as Waggott v Waggott [2018] EWCA Civ 722; TAB v FC (Short Marriage: Needs: Stockpiling) [2016] EWHC 3285; FF v KF [2017] EWHC 1903 (Fam); BD v FD (Financial Remedies: Needs) [2016] EWHC 594 (Fam); Juffali v Juffali [2016] EWHC 1684 (Fam); AAZ v BBZ [2016] EWHC 3234 (Fam); Scatliffe v Scatliffe [2016] UKPC 36; WM v HM [2017] EWFC 25; Hart v Hart [2017] EWCA Civ 1306; Sharp v Sharp [2017] EWCA Civ 408; Work v Gray [2017] EWCA Civ 270, and Birch v Birch [2017] UKSC 53. It also considers the recent decision of the Supreme Court in Mills v Mills [2018] UKSC 38 concerning post-divorce maintenance obligations between former partners, and the Privy Council decision in Marr v Collie [2017] UKPC 17 relating to the joint name purchase by a cohabiting couple of investment property.Part 2 focuses on child law, examining the law on parenthood and parental responsibility, including the parental child support obligation. This edition includes discussion of new case law on provision of child maintenance by way of global financial orders (AB v CD (Jurisdiction: Global Maintenance Orders)[2017] EWHC 3164), new case law and legislative/policy developments on section 54 of the Human Fertilisation and Embryology Act 2008 (parental orders transferring legal parenthood in surrogacy arrangements), and new cases on removing and restricting parental responsibility (Re A and B (Children: Restrictions on Parental Responsibility: Radicalisation and Extremism) [2016] EWFC 40 and Re B and C (Change of Names: Parental Responsibility: Evidence) [2017] EWHC 3250 (Fam)). Orders regulating the exercise of parental responsibility are also examined, and this edition updates the discussion with an account of the new Practice Direction 12J (on contact and domestic abuse), and controversial case law addressing the tension between the paramountcy of the child’s welfare and the protected interests of a parent in the context of a transgender father’s application for contact with his children (Re M (Children) [2017] EWCA Civ 2164). Part 2 also examines the issue of international child abduction, including in this edition the Supreme Court’s latest decision, on the issue of repudiatory retention (Re C (Children) [2018] UKSC 8). In the public law, this edition discusses the Supreme Court’s clarification of the nature and scope of local authority accommodation under section 20 of the Children Act 1989 (Williams v London Borough of Hackney [2018] UKSC 37). In the law of adoption, several new cases involving children who have been relinquished by parents for adoption are examined (Re JL & AO (Babies Relinquished for Adoption),[2016] EWHC 440 (Fam) and see also Re M and N (Twins: Relinquished Babies: Parentage) [2017] EWFC 31, Re TJ (Relinquished Baby: Sibling Contact) [2017] EWFC 6, and Re RA (Baby Relinquished for Adoption: Final Hearing)) [2016] EWFC 47).
Частини книг з теми "342.475 6":
1
von Roth, Dominik, and Ulrike Roesler. "Nr. 118 | S. [Selmar] Bagge, „Zur gegenwärtigen Parteistellung auf musikalischem Gebiete“, in: Monatschrift für Theater und Musik 4 (1858), Nr. 6 (Juni), S. 298–302." In Die Neudeutsche Schule – Phänomen und Geschichte, 1475–85. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-04923-0_118.
2
Zhang, Chenyang. "Trial." In Win in Chinese Courts, 63–76. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-3342-6_5.
Анотація:
AbstractThe pretrial preparation and trial will commence after appropriate service of the court documents on all parties. Ordinary procedure, summary procedure and special procedure are three concepts of parallel standing in the CPL. Except for cases under the summary procedure and the special procedure, all the other cases are tried under the ordinary procedure, which is the basis of all procedures and covers all necessary steps stipulated by the CPL. Our introduction will firstly be based on the ordinary procedure as well. (1) After serving court documents on all parties, the court needs to wait at least 30 days (or 45 days if the defendant is a foreign party without domicile in China) for the defendant to submit statement of defense and evidence. After that, the court can arrange a pretrial conference or a court hearing. There is no specific provision on the process and content of the pretrial conference, and in practice, the pretrial conference may proceed as an ordinary court hearing. Therefore, we advise that the parties try to figure out the process and content of the pretrial conference, and even make proper preparations with reference to the requirements of the ordinary court hearing. (2) In China, the steps of a court hearing generally include: court-conducted investigation, debates in court, closing argument and mediation. Among them, court-conducted investigation and debates in court are the core steps of court trial. To avoid unnecessary repetition and improve trial efficiency, Chinese courts sometimes combine these two steps together. During the Chinese court trial, we should pay attention to the following points: Firstly, judges are not passive listeners, but the leaders and controllers of all trial activities. Secondly, judges generally care more about the fact finding than the opinions of the parties on the law application. Thirdly, Chinese courts attach importance to the trial efficiency, and therefore the parties need to express their opinions as concisely as possible. Fourthly, the court trial may be made publicly available on the Internet; some court trials are also conducted online. (3) After finishing court hearing, the court will make the first-instance judgment and serve it on the parties through legal means to complete the rendering thereof. The parties may appeal within 15 days (or 30 days, if the appellant is a foreign party without domicile in China) and initiate the second-instance procedure. (4) Generally speaking, the trial process of second instance is not so different from that of first instance. The second-instance judgment is the effective final judgment. Under certain circumstances, the second-instance court may also remand the case to the first-instance court for retrial. (5) The trial time limit of first-instance cases under ordinary procedure is 6 months, and can be extended twice up to 15 months. The trial time limit of second-instance cases is 3 months, and can be extended once up to 6 months. But it is sometimes difficult for Chinese courts to close the case within the statutory trial time limit due to the litigation explosion. (6) In addition to the ordinary procedure, Chinese courts will try cases with little dispute and simple legal relations through the summary procedure. Cases under summary procedure are tried by one judge only, with shorter trial period and more flexible and simpler trial procedures. The summary procedure is applicable to most cases accepted by Chinese courts. However, the summary procedure is not frequently applied to foreign-related cases in China. (7) For money-judgment cases with a disputed amount below a certain standard, the trial procedure thereof will be further simplified and referred to as “Small Claims Procedure”. The first instance of such cases is final, and no appeal is allowed. However, the small claims procedure is not applicable to foreign-related cases. (8) At last, all civil cases in China can be divided into two categories: foreign-related cases and non-foreign-related cases. Foreign-related cases refer to cases with foreign elements, including cases where one of the litigants is a foreigner or a foreign organization, etc. There are special rules for the trial of foreign-related cases under the Chinese legal system, mainly to protect the litigious rights of foreign parties. However, it is worth noting that if the parties submit a non-foreign-related case to a foreign court or arbitration institution, it is highly likely that Chinese courts may refuse to recognize and enforce the judgment/award so rendered. This is one of the reasons why we have to distinguish foreign-related cases from non-foreign-related cases.
3
von Roth, Dominik, and Ulrike Roesler. "Nr. 7 | Johann Christian Lobe, „Fortschritt“, in: AmZ 50 (1848), Nr. 4 (26. Januar), Sp. 49–51; Nr. 5 (2. Februar), Sp. 65–69; Nr. 11 (15. März), Sp. 169–173; Nr. 21 (24. Mai), Sp. 337–341; Nr. 36 (6. September), Sp. 581–587; Nr. 37 (13. September), Sp. 5." In Die Neudeutsche Schule – Phänomen und Geschichte, 78–93. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-04923-0_7.
4
Schächtele, Alexander, Rainer Malisch, Björn Hardebusch, F. X. Rolaf van Leeuwen, Gerald Moy, Angelika Tritscher, Majorie van Duursen, et al. "WHO- and UNEP-Coordinated Exposure Studies 2000–2019: Findings of Polybrominated Substances (PBDE, HBCDD, PBB 153, PBDD/PBDF)." In Persistent Organic Pollutants in Human Milk, 299–342. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-34087-1_9.
Анотація:
AbstractThe concentrations of a number of polybrominated substances were determined in pooled human milk samples collected from up to 80 countries from all the United Nations Regional Groups. The samples were taken from one or more of the five exposure studies on persistent organic pollutants coordinated by the World Health Organization and the United Nations Environment Programme between 2000 and 2019.Large differences in levels were found for polybrominated diphenyl ethers (PBDE). The concentration of the sum of 6 PBDE congeners (∑PBDE6: BDE-47, BDE-99, BDE-100, BDE-153, BDE-154, BDE-183) of 135 pooled samples from 80 countries was in the range between 0.3 and 352 ng/g lipid (median 1.6 ng/g lipid). The highest concentrations were detected in the Western European and Others Group (including Australia, Israel, New Zealand, and the USA) in 2003. Time trends were assessed for 36 countries with repeated participation. Rates of decrease tend to fluctuate at near background levels; but at higher levels, a decreasing trend was observed for nearly all countries. Deca-BDE (BDE-209) contributed on average about 13% to ∑PBDE7 (sum of ∑PBDE6 plus BDE-209). The contribution of the octa-brominated diphenyl ether (octa-BDE) BDE-197 and nona-BDEs-206, -207, and -208 to the sum of 25 PBDE was in the range of the six recommended analytes and BDE-209. Therefore, their addition to the list of recommended analytes should be considered.The α-HBCDD levels of 102 pooled samples from 72 countries collected between 2006 and 2019 ranged between <0.1 and 15 ng/g lipid (median: 0.5 ng/g lipid). β-HBCDD and γ-HBCDD were in nearly all samples below the limit of quantification (LOQ for 90% of the samples: <0.1 ng/g lipid) or around the LOQ (max: 0.8 ng/g lipid). Thus, it can be concluded that α-HBCD is the predominant stereoisomer in human milk.Hexabromobiphenyl (PBB 153) was below the limit of quantification (0.5 ng/g lipid) in 106 of 110 pooled samples from 69 countries. In four samples, low concentrations of between 1.0 and 1.7 ng/g lipid were found.In addition to these chemicals listed by the Stockholm Convention on Persistent Organic Pollutants, in 38 pooled samples from 28 countries concentrations of polybrominated dibenzodioxins and -furans (PBDD/PBDF) were determined to assess their contribution to the overall sum of WHO2005 toxic equivalents (TEQ) with polychlorinated dibenzo-p-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF). PBDD and PBDF provided on average about 10% to the overall TEQ calculated as sum of WHO-PCDD/PCDF-TEQ and WHO-PBDD/PBDF-TEQ, when assuming the same toxic equivalency factors for brominated congeners as assigned to their chlorinated analogs. No correlations between PCDD/PCDF and PBDD/PBDF, or PBDD/PBDF and PBDE were found.
5
Boening, John. "[MATY’S]NEW REVIEW, 6 (1784), 321–342. M/H No. 479." In The Reception of Classical German Literature in England, 1760-1860, 97–107. Routledge, 2020. http://dx.doi.org/10.4324/9781003010821-28.
6
Taber, Douglass F. "Organic Functional Group Protection and Deprotection." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0016.
Анотація:
Corey R. J. Stephenson of Boston University devised (Chem. Commun. 2011, 47, 5040) a protocol using visible light for removing the PMB group from 1 to give 2. John F. Hartwig, now at the University of California, Berkeley, developed (Science 2011, 332, 439) a Ni catalyst for the cleavage of the durable aryl ether of 3 to give 4. Mark S. Taylor of the University of Toronto devised (J. Am. Chem. Soc. 2011, 133, 3724) the catalyst 6, which selectively mediated esterifi cation of 5 to 7. Jean-Marie Beau of the Université Paris-Sud added (Chem. Commun. 2011, 47, 2146) Et3 SiH following the Fe-catalyzed deprotection-protection of 8, resulting in clean conversion to the bis ether 9. Mahmood Tajbakhsh of the University of Mazandaran showed (Tetrahedron Lett. 2011, 52, 1260) that guanidine HCl catalyzed the conversion of 10 to 11. Stephen W. Wright of Pfizer/Groton established (Tetrahedron Lett. 2011, 52, 3171) that the new urethane protecting group of 12, stable to many conditions, could be deprotected to 13 under conditions that spared even a Boc group. Matthias Beller of the Leibniz-Institute for Catalysis protected (Chem. Commun. 2011, 47, 2152) the amine 14 as the readily hydrolyzed imidazole 16. Sentaro Okamoto of Kanagawa University found (Org. Lett. 2011, 13, 2626) a simple reagent combination for the removal of the sometimes reluctant sulfonamide from 17. Jordi Burés and Jaume Vilarrasa of the Universitat de Barcelona removed (Angew. Chem. Int. Ed. 2011, 50, 3275) the oxime from 19 by Au-catalyzed exchange with 20. Pengfei Wang of the University of Alabama, Birmingham, designed (J. Org. Chem. 2011, 76, 2040) a range of photochemically removable protecting groups for aldehydes and ketones. Rafael Robles of the University of Granada selectively protected (J. Org. Chem. 2011, 76, 2277) the diol 24 using the reagent created by the activation of 25. Berit Olofsson of Stockholm University prepared (Org. Lett. 2011, 13, 3462) the phenyl ester 28 by exposing 27 to the diaryl iodonium triflate. Kannoth Manheri Muraleedharan of the Indian Institute of Technology, Madras, selectively (Org. Lett. 2011, 13, 1932) esterified 29 to 30 with catalytic SmCl3.
7
Peppoloni, Diana. "Pratiche di mediazione non professionale degli studenti stranieri immigrati di prima o seconda generazione nel sistema scolastico italiano." In SAIL. Venice: Fondazione Università Ca’ Foscari, 2021. http://dx.doi.org/10.30687/978-88-6969-477-6/017.
Анотація:
The study investigates the extent and characteristics of the phenomenon of Child Language Brokering (CLB) in the Italian school system, namely the linguistic mediation of foreign students for their relatives and the institutions of the host country. A questionnaire administrated to 347 students of 36 nationalities of two secondary high schools of Perugia, detected the characteristics of CLB, foreign students’ attitude towards their language and culture of origin and those of the host country, and their relationship with the mediation practices. After an introduction and an overview of the literature on CLB, paragraphs 3 and 4 describe the materials and methods used and the results obtained. Finally, conclusions concern the enhancement of CLB in an inclusive perspective.
8
Squire, Nicholas, Kathleen Healy, and Joanna Broadbent. "Introduction." In Informing and Consulting Employees, 1–18. Oxford University PressOxford, 2005. http://dx.doi.org/10.1093/oso/9780199283644.003.0001.
Анотація:
Abstract This book explores the impact and effect of the Information and Consultation of Employees Regulations 2004 (SI 2004/3426) (the ICE Regulations). The Regulations, made under powers in section 42 of the Employment Relations Act 2004, implement in Great Britain the EU Information and Consultation (European Parliament and Council) Directive 2002/14/EC (the Information and Consultation Directive). Equivalent legislation has been implemented in Northern Ireland by the Information and Consultation of Employees Regulations (Northern Ireland) 2005 (Statutory Rule 2005/47). The ICE Regulations came into force on 6 April 2005. They are likely to extend considerably the circumstances in which larger and medium-sized employers are obliged to inform and consult with employee representatives in relation to matters affecting the workforce. As a result, the ICE Regulations may have a significant impact on the nature and structure of employment and industrial relations within workplaces in the United Kingdom.
9
L.Sihler, Andrew. "Comparison Of Adjectives." In New Comparative Grammar of Greek and Latin, 356–68. Oxford University PressNew York, NY, 1995. http://dx.doi.org/10.1093/oso/9780195083453.003.0073.
Анотація:
Abstract Adjectives in PIE as discussed in 337-47 are in what is called the positive degree: they express the generic force of the adjective without semantic coloration such as emphasis, attenuation, contrast, pejoration, and so on. There were several adjective stems in PIE, however, which did qualify the force of an adjective. As the daughter languages developed, one or another of these formations evolved into the ‘comparative and superlative degrees’ of adjectives familiar from the principal languages of Europe. One such suffix was ..-yos- (349-51), an INTENSIVE marker signifying ‘very; rather; to a marked degree’. This yields the L comparative, and is one of the ingredients in the G comparative. It is also the basis of the L and G superlative. Another stem, ..-(t)ero- (355-6), was PARTICUIARIZING and by implication ANT0NYMIC: ‘the hot one (not the cold one)’; ‘our (own)’.
10
Britnell, Richard. "Rural Settlement and Society." In Britain and Ireland 1050–1530, 368–87. Oxford University PressOxford, 2004. http://dx.doi.org/10.1093/oso/9780198731450.003.0019.
Анотація:
Abstract Since, as we saw in Chapter 4, the population of Britain declined between 1300 and 1530, we should expect abundant tangible evidence from rural sources. If total numbers in England fell from 4.5–6 m. in 1300 to around 2 m. in 1524, and if at least four-fifths of the population lived in rural settlements of various kinds, then rural population fell by at least 2.0–3.2 m. in the course of the period, and the decline was probably even greater between 1348 and the nadir of fifteenth-century contraction around 1450. If, too, many of the problems of the thirteenth-century countryside in southern England had resulted from shortages of land, we should expect those problems to be alleviated as the relationship between population and the land altered to increase per capita resources. Since Wales, Scotland, and Ireland experienced similar demographic contraction we should expect parallel evidence in their documentary and archaeological evidence. We should nevertheless expect the effects of rising resources per capita to be less marked in regions that had suffered less from land hunger before 1348 and that benefited less from manufacturing development and urban demand thereafter.
Тези доповідей конференцій з теми "342.475 6":
1
Allage, Carolina Junqueira, Denise Leite Maia Monteiro, Guilherme Ribeiro Ramires de Jesús, Aylana Ramos Gomes de Oliveira, Gabriella de Oliveira Flor Ferreira, and Leticia Freitas Simões. "A importância da vacina na adolescência como prevenção primária da infecção pelo HPV." In 47º Congresso da SGORJ e Trocando Ideias XXVI. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/jbg-2965-3711-2023133s1107.
Анотація:
Introdução: O papilomavírus humano (HPV) é uma das principais infecções sexualmente transmissíveis e está associado ao câncer de colo do útero, bem como a lesões pré-cancerosas e verrugas genitais. Apesar de ser um tipo de câncer prevenível, ocorrem aproximadamente 570.000 casos novos por ano em todo o mundo. O câncer de colo do útero é o quarto tipo mais comum de câncer entre as mulheres, causando 311.000 óbitos por ano e sendo a quarta principal causa de morte por câncer em mulheres (IARC, 2020). Desde 2014, o Sistema Único de Saúde (SUS) oferece a vacina contra o HPV para meninas entre 9 e 14 anos de idade. A vacina disponível no SUS inclui os sorotipos 6, 11, 16 e 18, sendo os dois últimos responsáveis por 70% dos casos de câncer de colo do útero. Objetivo: O objetivo deste estudo foi avaliar a eficácia da vacina contra o HPV na redução de verrugas genitais, lesões pré-cancerosas e/ou câncer de colo do útero após a conclusão do esquema vacinal. Método: Foi realizado um estudo de coorte prospectivo com 251 pacientes entre 13 e 30 anos de idade (média: 17,6 anos), atendidas em uma clínica privada no período de 2009 a 2018, que completaram o esquema vacinal contra o HPV e foram acompanhadas por 5 anos. Das 251 pacientes, 95 receberam a vacina bivalente da GSK e 156 receberam a vacina quadrivalente da MSD. Foram excluídas as pacientes que não completaram os 5 anos de acompanhamento. Durante o seguimento, foi realizada genotipagem do HPV por reação em cadeia de polimerase (PCR) nas pacientes que apresentaram lesões cervicais induzidas pelo HPV. Resultados: Das 251 pacientes que completaram o esquema vacinal, 6,7% (17/251) apresentaram infecção por HPV após a vacinação. Verrugas genitais foram observadas em 3,6% (9/251) das mulheres, sendo em 5,3% (5/95) das que receberam a vacina da GSK e em 2,6% (4/156) das que receberam a vacina da MSD. Lesões intraepiteliais de baixo grau (LSIL) foram observadas em 3,2% (8/251) dos casos, sendo em 3,2% (3/95) das que receberam a vacina da GSK e em 3,2% (5/156) das que receberam a vacina da MSD. A genotipagem por PCR revelou ausência dos tipos de HPV 16 e/ou 18 em todos os casos, e foram identificados os seguintes tipos de HPV: 31, 39, 51, 52 e 66. Ao longo do acompanhamento de 5 anos, todas as LSIL regrediram, e não houve nenhum caso de lesão de alto grau (HSIL). Conclusão: A vacina contra o HPV mostrou-se efetiva na redução de lesões induzidas pelo HPV. Nenhuma das pacientes que desenvolveram LSIL após a vacinação foi infectada pelos tipos de HPV oncogênicos contidos nas vacinas. Com a disponibilidade da vacina no SUS desde 2014, é necessário melhorar a cobertura vacinal, que sofreu uma importante redução para todas as doenças imunopreveníveis devido à pandemia de COVID-19. Somente dessa forma poderemos reduzir as taxas de câncer de colo do útero em nosso país.
2
Семикова, Г. В., С. В. Дора та З. В. Швец. "ДИНАМИКА ПОКАЗАТЕЛЕЙ ИНСУЛИНОРЕЗИСТЕНТНОСТИ И РЕПРОДУКТИВНЫХ НАРУШЕНИЙ У ПАЦИЕНТОК С ОЖИРЕНИЕМ ПОСЛЕ ВЫПОЛНЕНИЯ РУКАВНОЙ ГАСТРОПЛАСТИКИ". У X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-158.
Анотація:
ЦЕЛЬ: оценить влияние рукавной гастропластики на менструальный цикл и уровень половых гормонов
у пациенток репродуктивного возраста с ожирением
МАТЕРИАЛЫ И МЕТОДЫ: проведено наблюдательное проспективное исследование 32 пациенток
с индексом массы тела (ИМТ) ≥ 35 кг/м2 в возрасте от 19 до 38 лет с различными нарушениями менстру-
ального цикла (НМЦ). Пациенткам выполняли рукавную гастропластику (РГ) по стандартной методике.
Исходно и через 1 год после операции оценивали ИМТ, на 3-5 день менструального цикла при его наличии
определяли уровень гонадотропных гормонов: фолликулостимулирующего (ФСГ) и лютеинизирующего
(ЛГ), уровень общего эстрадиола, свободного тестостерона и пролактина, а также антимюллерова гормона
(АМГ) как маркера овариального резерва. Уровень прогестерона определяли на 21-23 день менструаль-
ного цикла (при его наличии). Индекс инсулинорезистентности НОМА-IR рассчитывали по стандартной
формуле, за инсулинорезистентность принимали значение более 2,7.
РЕЗУЛЬТАТЫ: медиана возраста пациенток составила 29 (22 – 35) лет, ИМТ исходно - 38,8 кг/м2
(36,2 – 40,2). Структура МНЦ была представлена следующим образом: олигоменорея выявлялась у 28,1% па-
циенток (n = 9), аномальные маточные кровотечения у 53,1% пациенток, (n = 17), аменорея на протяжении
как минимум 6 месяцев до оперативного вмешательства – у 18,8% пациенток (n = 6). Исходно НОМА-IR был
равен 5,4 (3,2 – 8,1), что свидетельствует об инсулинорезистентности; только у одной пациентки HOMA-IR
был менее 2,7. Исходно уровень ФСГ составил 4,6 мМЕ/мл (3,0 – 6,4), ЛГ – 11,2 мМЕ/мл (8,4 – 15,2). Уровень
эстрадиола общего составил 362 пг/мл (318 – 414), свободного тестостерона – 5,7 пг/мл (4,2 – 6,8). Уровень
пролактина был равен 448 мМЕ/л (316 – 522). Уровень прогестерона составил 12,3 нмоль/л (7,3 – 18,8).
Уровень АМГ составил 2,9 нг/мл (1,9 - 3,5). Значимых различий в уровне описанных гормонов у пациенток
с различными НМЦ выявлено не было, также не выявлялось корреляции с возрастом и ИМТ.
Через 1 год после РГ у всех пациенток ИМТ снизился до 27,3 кг/м2 (24,6 – 29,1), р < 0,001. НОМА-IR был
ниже исходных значений: 2,8 (1,6 – 3,6). У 22 женщин произошла нормализация менструального цикла;
через 1 год после операции у 4 женщин сохранялись аномальные маточные кровотечения, у 3 – олигомено-
рея, у 3 – аменорея. Описанные пациентки были старше, однако различия в возрасте не были статистически
значимы. Уровень ФСГ через 1 год после РГ повысился и составил 11,6 мМЕ/мл (8,2 – 15,6), р = 0,042; уровень
ЛГ снизился по сравнению с исходными значениями до 6,4 мМЕ/мл (3,2 – 9,1), р = 0,048. Уровень общего
эстрадиола снизился до 320 пг/мл (265 – 373), однако различия статистически не значимы. Свободный
тестостерон был ниже исходных значений – 3,2 пг/мл (2,5 – 4,8), р = 0,034. Уровень пролактина значимых
изменений не претерпел. Уровень АМГ через 1 год после операции возрос до 3,5 нг/мл (2,9 – 4,5), р = 0,042;
уровень прогестерона – до 26,3 нмоль/л (15 – 42), р = 0,024.
ВЫВОДЫ: выполнение РГ у пациенток с ожирением приводит к снижению инсулинорезистентности,
нормализации менструальной функции у большинства пациенток, что сопровождается повышением
уровня АМГ, изменением соотношения гонадотропных гормонов и уменьшением уровня свободного
тестостерона, а также повышением уровня прогестерона.
3
Bednar, Martin, and Daniel Marton. "IMPACT OF CLIMATE CHANGE ON HYDROLOGICAL AND METEOROLOGICAL QUANTITIES IN WATERSHED SCALE." In 22nd International Multidisciplinary Scientific GeoConference 2022. STEF92 Technology, 2022. http://dx.doi.org/10.5593/sgem2022v/3.2/s12.11.
Анотація:
Climate change�s effect on nature, the human population and water resources have become a serious issue. It affects the delicate balance between precipitation, evaporation, discharge and other interactions between the atmosphere and surface, which is represented by the water cycle as we know it. The adaptation of water resources to changing hydrological conditions within basins is crucial. However, the uncertainty of climate change makes it difficult for hydrological models to evaluate future conditions. To suppress the uncertainty that stems from the hydrological model itself, we propose a new modified lumped water balance model in monthly time steps to simulate the rainfallrunoff process more precisely, which will help to evaluate the predicted hydrological and climatological conditions under the uncertainty of climate change. Assessment of the effects of climate change is presented on the catchment above the Vir I reservoir on the Svratka River in the Czech Republic in Central Europe. The uncertainty of climate change is represented by an ensemble of future climatological projections using representative concentration pathways (RCP) scenarios. Two ensembles were generated: the first using RCP 4.5 and the second using RCP 8.5. Both scenarios were coupled with 18 global climate models which are available in LARS-WG 6 software. Analysis of the generated climatological quantities for both ensembles in the 2030s, 2050s, and 2090s periods on annual average relative to baseline values showed an increase in mean temperature of 21.4% (1.4�C), 33.1% (2.2�C) and 55.5% (3.7�C), an increase of potential evapotranspiration of 7.2%, 11.4% and 20.5%, and an increase in precipitation of 4.8%, 5.3% and 5.5%, respectively. Evaluated long-term mean streamflow showed a decrease in the 2030s, 2050s and 2090 of 1.0%, 3.1% and 2.9%, respectively, for RCP 4.5 and an increase of 1.8% in the 2030s but then also a decrease in the 2050s and 2090s of 2.3% and 17.9%, respectively, for RCP 8.5.
4
Лютиков, А. А., В. В. Костюничев, В. А. Голотин, and М. М. Вылка. "PRELIMINARY RESULTS OF STUDIES ON ARTIFICIAL TRIPLOIDIZATION OF WHITEFISH." In DEVELOPMENT AND MODERN PROBLEMS OF AQUACULTURE. ООО "ДГТУ-Принт" Адресс полиграфического предприятия 344003 пл Гагарина, зд. 1, 2023. http://dx.doi.org/10.23947/aquaculture.2023.55-59.
Анотація:
Obtaining triploid fish in modern aquaculture is aimed to solve the problem of growth reduction during the maturation of cultivated objects. Our study shows a fundamental possibility of triploidization of whitefish from Coregonidae family (in particular Stenodus leucichthys nelma) with the use the hydrostatic shock. The triploidization experiment included a control and five experimental timepoints within a time period of 204-476 degree-minutes after fertilization. In each of them inseminated nelma eggs were placed under hydrostatic pressure of 650 bar for 5 minutes with a time interval of 68 degree minutes. The most effective protocol for obtaining nelma triploids was established at 340 degree minutes after insemination that made it possible to obtain a triploidization rate close to 100% according to flow cytometry results. The best survival among experimental nelma eggs was 34.6%, however, this is significantly less than in the control (61.0%). The growth rate of obtained triploid and diploid were comparable, however, the survival rate in triploids was lower: 44.5% (55.6% in diploids) with a 6-times higher incidence of skeletal deformities. Disturbances in skeleton development are expressed generally in the caudal spine curvature and jaw deformation.
5
Константинов, К. В., М. Ю. Плетнев, В. В. Веткин, В. А. Образцова, and Е. П. Юмашева. "THE USE OF THE METHOD OF BIOACOUSTIC CORRECTION IN THE MEDICAL AND SOCIAL REHABILITATION OF DRUG ADDICTS." In Антология российской психотерапии и психологии. Crossref, 2023. http://dx.doi.org/10.54775/ppl.2023.72.47.001.
Анотація:
У наркозависимых проводились групповые психотерапевтические занятия в сочетании с биоакустической коррекцией (БАК). Обследован 31 человек в период восстановления (19 мужчин и 12 женщин), средний возраст 39 лет. Стаж употребления: от 5 до 20 лет. Средний срок трезвости 8,7 месяца. Процедуры БАК заключались в прослушивании больными акустических сэмплов, скоррелированных с текущей ЭЭГ. Продолжительность процедуры 20 минут, курс – от 8 до 22 процедур. До и после курса БАК проводилось тестирование по десятибальным шкалам. Статистический анализ проводился с использованием Microsoft Excel 2010 и «Statistica 6.0». В ходе коррекции наблюдалось достоверное снижения «эмоциональной лабильности» с 6,6±2,3 до 3,2±2,2 балла (p<0,001), «агрессивности» с 4,8±3,0 до 2,0±1,8 (p<0,001), «времени засыпания» с 4,4±3,0 до 2,2±1,6 (p<0,01), «чуткости сна» с 5,1±2,6 до 2,8±2,5 (p<0,01), «страхов» с 4,9±3,4 до 2,7±2,5 (p<0,05), «колебаний артериального давления» с 2,5±2,9 до 1,4±1,4 (p<0,05), улучшение «концентрации внимания» с 4,5±1,6 до 7,3±1,9 (p<0,001), уменьшение «потливости» с 3,0±3,0 до 1,4±1,7 (p<0,05), «головокружения» с 2,0±2,4 до 1,1±1,4 (p<0,05), «головных болей» с 2,7±2,8 до 1,8±1,8 (p<0,05), «нарушений памяти» с 4,9±2,3 до 3,3±2,5 (p<0,01), «утомляемости» с 6,0±2,8 до 3,6±2,5 (p<0,001) и «метеозависимости» с 4,6±3,2 до 3,7±3,1 балла (p<0,05). Так же снижался уровень тревоги, неконтролируемые приступы ярости и «градус тяги». Со слов пациентов после процедур уменьшалось «напряжение мозга» и «прерывистость мыслей», что существенно увеличивало эффективность групповых психотерапевтических занятий. Наиболее заметные изменения наблюдались после 5-6 процедуры и ближе к концу курса БАК. Представляется перспективным дальнейшие наблюдения за восстановлением функций центральной нервной системы у наркозависимых с применением метода биоакустической коррекции.
6
Vedharaj, S., R. Vallinayagam, S. Mani Sarathy, and Robert W. Dibble. "Improving Vegetable Oil Fueled CI Engine Characteristics Through Diethyl Ether Blending." In ASME 2016 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/icef2016-9339.
Анотація:
In this research, the flow and ignition properties of vegetable oil (VO) are improved by blending it with diethyl ether (DEE). DEE, synthesized from ethanol, has lower viscosity than diesel and VO. When DEE is blended with VO, the resultant DEEVO mixtures have favorable properties for compression ignition (CI) engine operation. As such, DEEVO20 (20% DEE + 80% VO) and DEEVO40 (40% DEE + 60% VO) were initially considered in the current study. The viscosity of VO is 32.4*10−6 m2/s; the viscosity is reduced with the increase of DEE in VO. In this study, our blends were limited to a maximum of 40% DEE in VO. The viscosity of DEEVO40 is 2.1*10−6 m2/s, which is comparable to that of diesel (2.3*10−6 m2/s). The lower boiling point and flash point of DEE improves the fuel spray and evaporation for DEEVO mixtures. In addition to the improvement in physical properties, the ignition quality of DEEVO mixtures is also improved, as DEE is a high cetane fuel (DCN = 139). The ignition characteristics of DEEVO mixtures were studied in an ignition quality tester (IQT). There is an evident reduction in ignition delay time (IDT) for DEEVO mixtures compared to VO. The IDT of VO (4.5 ms), DEEVO20 (3.2 ms) and DEEVO40 (2.7 ms) was measured in IQT. Accordingly, the derived cetane number (DCN) of DEEVO mixtures increased with the increase in proportion of DEE. The reported mixtures were also tested in a single cylinder CI engine. The start of combustion (SOC) was advanced for DEEVO20 and DEEVO40 compared to diesel, which is attributed to the high DCN of DEEVO mixtures. On the other hand, the peak heat release rate decreased for DEEVO mixtures compared to diesel. Gaseous emissions such as nitrogen oxide (NOX), total hydrocarbon (THC) and smoke were reduced for DEEVO mixtures compared to diesel. The physical and ignition properties of VO are improved by the addition of DEE, and thus, the need for the trans-esterification process is averted. Furthermore, this blending strategy is simpler and enables operation of straight run oils and fats in CI engine, replacing diesel completely.
7
Мустафина, С. В., В. И. Алфёрова, О. Д. Рымар, Л. В. Щербакова, Е. В. Каштанова та Ю. И. Рагино. "УРОВНИ АДИПОЦИТОКИНОВ У ЖЕНЩИН 25-44 ЛЕТ С РАЗНЫМИ МЕТАБОЛИЧЕСКИМИ ФЕНОТИПАМИ". У X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-154.
Анотація:
ЦЕЛЬ: изучить особенности уровней адипоцитокинов (адипонектин, лептин, адипсин, интерлейкин-6
(ИЛ-6), фактор некроза опухоли α (ФНОα)) у женщин 25-44 лет с разными метаболическими фенотипами.
МАТЕРИАЛЫ И МЕТОДЫ: в 2013–2016 гг. в Новосибирске в ходе одномоментного одноцентрового ис-
следования была обследована случайная городская популяционная выборка мужчин и женщин 25–44 лет
(n=1512, из них 840 женщин), в анализ включены показатели 655 женщин. В каждой группе изучались ме-
таболически здоровый фенотип (МЗФ) и метаболически нездоровый фенотип (МНЗФ). Для оценки метабо-
лического здоровья использованы критерии Международной Федерации Диабета (IDF), 2005 года для диа-
гностики метаболического синдрома (МС). Методом мультиплексного анализа с использованием панелей
Human Metabolic Hormone V3 (MILLIPLEX) и Human Adipokine Panel 1, на проточном флуориметре Luminex
MAGPIX определяли уровни ИЛ-6 (n=256), ФНОα (n=365), адипонектина (n=187), адипсина (n=368) и лептина
(n=370). Статистическая обработка проведена с помощью пакета программ SPSS (v. 13.0). Адипоцитокины
распределены ненормально, поэтому данные представлены в виде Ме [25;75], где МЕ – медиана, [25;75] –
процентили. Сравнение двух независимых групп по количественным признакам с ненормальным рас-
пределением произведено с помощью непараметрического критерия Манна-Уитни. При сравнении трех
и более независимых групп использовался критерий Краскела-Уоллиса. Различия считались статистически
значимыми при p<0,05, очень значимыми при p≤0,01, высоко значимыми при p≤0,001.
РЕЗУЛЬТАТЫ: обследовано 655 женщин, средний возраст 36,3±5,4 лет, сред-
ний ИМТ 25,0±5,7 кг/м2. В обследованной выборке медиана адипонектина составила
83,4 [37,4; 120,8] мкг/мл, лептина – 11,8 [5,6; 19,6] нг/мл, адипсина - 24,9 [8,6; 33,2] мкг/мл, ИЛ-6 -
6,9 [1,3; 14,7] пг/мл, ФНОα - 13,1 [3,7; 24,4] пг/мл. Медиана лептина в группе МЗФ в 1,9 раз ниже, чем в группе
МНЗФ - 10,2 [4,4; 16,9] нг/мл против 19,1 [10,9; 28,0] нг/мл (р<0,0001). Медианы адипсина и адипонектина
в сравниваемых группах не отличались (24,8 [8,1; 33,2] и 25,9 [10,0; 33,2] мкг/мл (р=0,534), и 79,5 [37,5; 139,2]
и 87,7 [36,3; 118,5] мкг/мл (р=0,642), соответственно. Медиана ИЛ-6 у женщин с МЗФ значимо ниже, чем
в группе с МНЗФ - 6,9 [1,2; 12,4] и 11,7 [2,2; 18,7] пг/мл соответственно (р=0,007), медиана ФНОα также ниже
в группе МЗФ- 12,7 [3,2; 23,6] пг/мл против 13,8 [4,5; 27,3] пг/мл соответственно (р=0,044).
ВЫВОДЫ: в популяционной выборке женщин 25-44 лет г. Новосибирска метаболически нездоровые
женщины уже имеют более высокие показатели лептина и провоспалительных цитокинов (ИЛ-6, ФНОα),
чем метаболически здоровые. Значения адипонектина и адипсина не отличались в исследуемых группах.
ФИНАНСИРОВАНИЕ: бюджетная тема «Эпидемиологический мониторинг состояния здоровья населе-
ния и изучение молекулярно-генетических и молекулярно-биологических механизмов развития распро-
страненных терапевтических заболеваний в Сибири для совершенствования подходов к их диагностике,
профилактике и лечению» (Рег. № 122031700094-5).
8
Hormann, A., E. J. C. Olson, P. F. Barbara, M. R. Arkin, E. D. A. Stemp, R. E. Holmlin, and J. K. Barton. "Time Resolved Electron Transfer Studies Between Metallointercalators in DNA." In International Conference on Ultrafast Phenomena. Washington, D.C.: Optica Publishing Group, 1996. http://dx.doi.org/10.1364/up.1996.sab.6.
Анотація:
This paper reports the first ultrafast studies on the rates of DNA-mediated forward and reverse electron transfer between photoexcited [M(phen)2dppz]2+ (M=Ru or Os, phen =1,10-phenanthroline, dppz = dipyrido[3,2:a-2′,3′:c]-phenazine) and various electron acceptors in order to ultimately determine the distance dependence of electron transfer kinetics with DNA as an environment.1,2 Previously Barton, Turro, and coworkers have presented evidence that electron transfer in DNA can occur rapidly over an extraordinarily large distance3 with a more shallow distance dependence than that for other media, such as liquids and proteins.4,5 Some theoretical work supports the shallow distance dependence which is attributed to a long range, thermally activated coherent mechanism involving virtual excitation of the DNA "bridge".6 Utilizing time-correlated single photon counting (TCSPC), we observe a substantial fraction of photoexcited [M(phen)2dppz]2+ (M=Ru, Os) exhibits fast oxidative quenching (kq > 3 x 1010 s−1) in the presence of intercalating Rh(III) acceptors while the remaining excited-state species exhibit a range of quenching constants less than 108 s_1. Transient-absorption experiments on the picosecond timescale indicate that, for a series of donors bound to mixed sequence DNA, the majority of back electron transfer is also very fast (ca. 1010 s−1). Importantly, the rate constant for the fast ground-state recovery is independent of loading of Rh(III) intercalators on DNA. As shown in Figure 1, regardless of whether the average loading of metal complexes is 1 in 33 basepairs or 1 in 10 basepairs, the fast bleach recovery exhibited by [Ru(phen)2dppz]2+ is well fit under all conditions by an exponential decay of 9 x 109s−1. Separate ultrafast data suggests that, like the recombination reaction, the fast quenching *M2+ is simple first-order at early time. If the early time electron transfer kinetics were not simple first order, and the electron transfer rate decayed with an exponential distance dependence (i.e. ≅ a factor of 30 per base step [3.4 Å]), our TCSPC apparatus should be able to observe some evidence of the slower components with rate constants in the range of 1010 - 108 s−1. The absence of rates in this range is evidence that the electron transfer is simple first order at time < 10 ns. This result has implications with regards to the donor-acceptor separations on DNA. Throughout most of the titration, intercalators are dilute on the double helix and statistics show that the amount of fast quenching and ground-state recovery observed is too great to be accounted for by random loading of nearest-neighbor pairs. Thus, either the electron transfer reaction must involve clustering of the donor and acceptor on the helix or the DNA-mediated interaction must occur over long distance.
9
Kaur, Inderjit, Swarupa Mitra, Manoj Kumar Sharma, Upasna Saxena, Parveen Ahlawat, Amit Kumar Choudhary, Sarthak Tandon, and Prashant Surkar. "Case report of vaginal melanoma." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685371.
Анотація:
Primary malignant melanoma of vagina is a rare disease with a predilection for local recurrence, distant metastasis and short survival time. Due to the low incidence and lack of reporting in the literature, treatment choices still remain controversial. We describe 2 cases of vaginal malignant melanoma. A 42 yr old female presented with complaints of post coital and per vaginal bleed of 1 month duration. Examination findings show growth 6 cm x 6 cm on anterior vaginal wall, another 3 x 3 cm lesion on right lateral vaginal wall. Vaginal biopsy showed malignant melanoma, S-100 and HMB-45 positive while negative for CK and LCA. MRI Whole abdomen showed altered lesion [3.8cm (AP), 6.0cm (TR) and 4.9cm (CC)] in upper 2/3rd of vagina extending into vaginal fornices and abutting right lower cervix superiorly, right paravaginal extension and mesorectal fascia. No significant enlarged lymph nodes were seen. In view of localised disease she underwent Type III Radical hysterectomy with bilateral salpingo-ophorectomy with bilateral pelvic lymphnode dissection with total vaginectomy. Histopathology s/o 2 tumour nodules, one located in the anterior vaginal cuff measuring – 5 x 5 x 3.2 cm, another located in right lateral vaginal cuff measuring 2.5 x 3 x 1.5 cm, malignant melanoma with involvement of the cervix with full thickness stromal invasion (2.8/2.8 cm,) invading perivaginal soft tissue, distance of invasive carcinoma from closest stromal margin <0.1cm (12 O’ clock), LVI, PNI – not seen, all pelvic LN free (0/25). In view of positive margin and full thickness stromal involvement, she received radiotherapy to pelvis and Inguinal region to a dose of 45 Gy/25# followed by a boost of 16 Gy/8# to the tumour bed till 01/01/16. Another case is a 40 yrs female, presented with complaints of bloody discharge per vaginum of 4 months duration. On examination, there was a large growth occupying the vagina till introitus. Cervix normal, para free. MRI Pelvis showed altered lesion involving left lateral uterine cervix and upper 2/3rd of vagina with full thickness stromal involvement with mild left parametrial, anterior and posterior paravaginal extension, measuring 2.9 x 4.5 x 5.3 cm. Few subcmlymphnodes were seen in bilateral external and internal iliac regions (L>R). Vaginal Biopsy was suggestive of Malignant Melanoma, expressing S-100, HMB 45 and SDX-10. Metastatic work up was negative. She underwent RH with total vaginectomy with bilateral PLND with RPLND. HPR showed exophytic black growth seen involving all quadrants of vagina, extending upwards into both lips of cervix – 7 x 6 x 2.5 cm, Malignant melanoma, distance of invasive carcinoma from closest margin: <0.1 cm (paravaginal soft tissue), 3/8 right Pelvic LN, ECE +, 01/9 Left pelvic LN, ECE absent, 0/6 Right common iliac LN, 0/1 Reperitoneal LN was seen. She received adjuvant radiotherapy to a dose of 50 Gy/25# to the pelvis and inguinals→ boost of 6 Gy/3# to nodal regions showing ECE & 10 Gy/5# to the primary region.
10
Иванов, М. А., А. Н. Звягинцева та Э. И. Панасюк. "ЯВЛЯЕТСЯ ЛИ САХАРНЫЙ ДИАБЕТ И ЗАБОЛЕВАНИЯ ЩИТОВИДНОЙ ЖЕЛЕЗЫ ФАКТОРАМИ РИСКА РАЗВИТИЯ ОСЛОЖНЕНИЙ НОВОЙ КОРОНАВИРУСНОЙ ИНФЕКЦИИ?" У X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-288.
Анотація:
ЦЕЛЬ: поиск ответа на вопрос: является ли сахарный диабет и заболевания щитовидной железы факторами риска развития осложнений COVID-19?
МАТЕРИАЛЫ И МЕТОДЫ: проспективно обследованы и ретроспективно проанализированы результаты оказания помощи 415 больным (в возрасте от 20 до 95 лет) инфекционного отделения COVID-19 с острой
вирусной пневмонией.
Из 70 пациентов с углеводными нарушениями 53 человек страдали сахарным диабетом (СД) 2 типа,
а у 17 больных имел место сахарный диабет 1 типа (основная группа), а у 345 обследуемых не было указанных расстройств углеводного обмена.
Был проанализирован показатель глюкозы у пациентов, не имеющих диагноза сахарный диабет.
Заболевания щитовидной железы были зарегистрированы у 25 человек.
Были проанализированы особенности течения COVID-19 на фоне СД и без него, а также у пациентов
с различными заболеваниями щитовидной железы. Среди анализируемых осложнений спонтанные гематомы встречались у 25 человек, желудочно-кишечные кровотечения (ЖКК) – у 20 пациентов, инфаркт
миокарда (ОИМ) и острое нарушение мозгового кровообращения (ОНМК) наблюдалось у 14 больных,
венозные тромбоэмболические осложнения были зарегистрированы у 11 пациентов (ВТЭО: тромбофлебит – 9, флеботромбоз – 3), мезентеральный тромбоз был обнаружен у 5 человек.
РЕЗУЛЬТАТЫ: среди всех больных 80 человек (19,3%) столкнулись с осложнениями, среди которых
в 10 наблюдениях (12,5%) зарегистрирован летальный исход. Лица, страдающие СД 1 и 2 типов, имели
осложненное течение болезни в 38,6% случаев (27 человек; р <0.05), летальный исход среди них был
у 6 пациентов (22,2%).
Среди пациентов с СД 40,0% (28 человек) подверглись острой диабетической декомпенсации на фоне
COVID-19.
Глюкоза крови была повышена у 12,2% обследуемых (42 человека), а понижена у 1,4% (5 человек).
С осложнениями было связано 30,9% случаев (13 человек) гипергликемии и 60,0% (3 человека, p <0,001)
гипогликемии.
Среди пациентов, имеющих заболевания щитовидной железы, с осложнениями столкнулось 6 человек
(24,0%).
ВЫВОДЫ: наличие СД повышает вероятность развития осложнений, а также летального исхода на фоне
COVID-19. Наличие новой коронавирусной инфекции увеличивает вероятность декомпенсации сахарного
диабета. На основании полученных данных, можно говорить о том, что сахарный диабет, а также изменение
уровня глюкозы (как снижение, так и повышение) является факторами риска тяжелого течения COVID-19.
В настоящем исследовании влияния заболеваний щитовидной железы на течение новой коронавирусной
инфекции выявлено не было.
Звіти організацій з теми "342.475 6":
1
Larramendy, Peter, Linnea Hall, and Annie Little. Landbird trends 2016–2021, and 2021 annual report: Channel Islands National Park. National Park Service, August 2023. http://dx.doi.org/10.36967/2299629.
Анотація:
The National Park Service (NPS) began monitoring landbirds at Channel Islands National Park in 1993 as part of its long-term inventory and monitoring program. The park’s landbird monitoring later became part of the NPS Inventory and Monitoring Division’s Mediterranean Coast Network long-term monitoring programs. Consequently, landbird monitoring has been conducted during every breeding season since 1993. In this report, we summarize data collected during the 2021 breeding season and we analyze trends in a select number of species. Landbird monitoring was conducted between 10 March and 22 May 2021. Using distance-based sampling methods in a standardized protocol, birds were counted on 334 of 338 permanent point count stations (99%) across the Channel Islands monitored for landbirds. These surveys were conducted at 29 of 33 points on Santa Barbara Island, 8 of 8 on East Anacapa Islet, 112 of 112 on Santa Cruz Island, 40 of 40 on San Miguel Island, and 145 of 145 on Santa Rosa Island. Four points on Santa Barbara Island were not counted due to nesting California Brown Pelicans (Pelecanus occidentalis) and Western Gulls (Larus occidentalis); 3 of 4 points (i.e., 17, 19, and 20) were also not counted in 2016–2021 to avoid disturbing breeding pelicans. This was the first monitoring season that the permanent line transects on Santa Barbara, East Anacapa, and San Miguel Islands were not surveyed. During the 2021 monitoring season, Channel Islands National Park decided to stop using line transects and focus on point count stations only, based on an external review of the landbird monitoring program. Fifty-six bird species were counted at point count stations across all of the islands in 2021. Parkwide, 40 of these species are breeders in Channel Islands National Park. Parkwide, the 10 most detected breeding landbirds in 2021 were, in descending order: Spotted Towhee, Song Sparrow, Bewick’s Wren, Orange-crowned Warbler, House Finch, Western Meadowlark, Horned Lark, Common Raven, Island Scrub-Jay, and Pacific-slope Flycatcher (scientific names in Table 2 and Appendix A). On East Anacapa Islet, 26 landbird species have been counted since 1993; 7 species were counted in 2021. No new transient species were detected in 2021; 6 transient or visiting species have been counted on the island overall since 1993. On Santa Barbara Island, 50 landbird species have been counted since 1993; 13 species were counted in 2021. Lincoln’s Sparrow was a new transient species counted in 2021 on Santa Barbara; 23 transient or visiting species have been counted on the island since 1993. On Santa Cruz Island, 78 landbird species have been counted since 2013; 45 species were counted in 2021. Hermit Warbler, Lawrence’s Goldfinch and Warbling Vireo were new transient species counted in 2021 on Santa Cruz Island; 21 transient or visiting species have been counted on this island since 2013. On San Miguel Island, 70 landbird species have been counted since 1993; 10 were counted in 2021. No transient species were counted in 2021; 32 transient or visiting species have been counted on the island since 1993. On Santa Rosa Island, 78 landbird species have been counted since 1994; 39 were detected in 2021. No new transient species were counted in 2021 on Santa Rosa; 21 transient or visiting species have been counted on the island since 1994. Nonnative and invasive birds were counted on only 1 of the 5 islands in 2021: 23 European Starlings on Santa Rosa Island. However, anecdotal sightings of nonnative species occurred more frequently (i.e., outside of survey times) on Santa Cruz and Santa Rosa Islands in 2021. The highest numbers of nonnative species detections occurred on Santa Rosa Island, with 25 detections of Eurasian Collared Dove (primarily at the Historic Ranch), 18 detections of European Starling (Historic Ranch), 2 detections of Brown-headed Cowbird, and 1 Rock Pigeon detection (Historic Ranch). Other species were not reported by Channel Islands National Park landbird monitors or in eBird in 2021. This was the first annual monitoring report since the Coonan and Dye (2016) trend report to incorporate density estimates for particular species across Channel Islands National Park. Parkwide, 13 species were analyzed using the Distance Package in R. Of the 13 species analyzed, 5 had either increasing or decreasing densities from 2016 to 2021. All park islands except for Santa Barbara had a species that showed an increasing or decreasing trend from 2016 to 2021. Horned Lark and House Finch on San Miguel Island were the only species to show decreasing trends from 2016 to 2021, which is opposite from the trend presented by Coonan and Dye (2016).
2
Monthly Infographics Report: April 2023. Microgovernance Research Initiative (MGR), 2023. http://dx.doi.org/10.57189/mgrinfapr24.
Анотація:
A total of 1705 violent incidents occurred in April 2023 which is 6% less than the previous month. The incidents are mostly triggered by politics, access to resources, and other socio-economic factors. More than 316 deaths and 1856 injuries have been recorded from these incidents. Around 3864 people have been arrested in April connected to violent incidents. Some 52 properties have been destroyed in the same time. The highest number of violent incidents have been recorded as clashes and attacks (473). Some 295 incidents of political violence were also recorded at the same time and 36 deaths were directly triggered by politics. Geographically, Chittagong (342) scores the highest number of violence followed by Dhaka (339), Rajshahi (257), and Khulna (246). Among 168 protests in Bangladesh, 100 protests were triggered by politics. 20.73% of protests were done by BNP while Awami League organized 14.63% of protests in April. At least 22 protests were held across Bangladesh, demanding the repeal of the Digital Security Act and freedom of press in the country in April. While some 53.04% of political violence contributed by Bangladesh Awami League & affiliates, similarly, 38.26% contributed by the Bangladesh Nationalist Party (BNP). Whereas 67% incidents were rural, 33% violence incidents took place in urban areas in April.
3
Monthly Infographics Report: April 2023. Microgovernance Research Initiative (MGR), 2023. http://dx.doi.org/10.57189/mgrinfapr23.
Анотація:
A total of 1705 violent incidents occurred in April 2023 which is 6% less than the previous month. The incidents are mostly triggered by politics, access to resources, and other socio-economic factors. More than 316 deaths and 1856 injuries have been recorded from these incidents. Around 3864 people have been arrested in April connected to violent incidents. Some 52 properties have been destroyed in the same time. The highest number of violent incidents have been recorded as clashes and attacks (473). Some 295 incidents of political violence were also recorded at the same time and 36 deaths were directly triggered by politics. Geographically, Chittagong (342) scores the highest number of violence followed by Dhaka (339), Rajshahi (257), and Khulna (246). Among 168 protests in Bangladesh, 100 protests were triggered by politics. 20.73% of protests were done by BNP while Awami League organized 14.63% of protests in April. At least 22 protests were held across Bangladesh, demanding the repeal of the Digital Security Act and freedom of press in the country in April. While some 53.04% of political violence contributed by Bangladesh Awami League & affiliates, similarly, 38.26% contributed by the Bangladesh Nationalist Party (BNP). Whereas 67% incidents were rural, 33% violence incidents took place in urban areas in April.