Статті в журналах з теми "2003 c-488"

OM OG AF H. C. ANDERSEN ANDERSEN. H.C. Andersens samlede værker. Eventyr og Historier I-111. Udgivet af Det Danske Sprog- og Litteraturselskab under redaktion af Klaus P. Mortensen. Udgivere: Laurids Kristian Fahl, Esther Kielberg, Klaus P. Mortensen, Jesper Gehlert Nielsen under medvirken af Finn Gredal Jensen. Det Danske Sprog- og Litteraturselskab/ Gyldendal 2003. 560 s. + 528 s + 488 s. Jackie Wullschlager: H.C. Andersen. En biografi. På dansk ved Pia Juul. Hans Reitzels Forlag. 2002. 504 s. Jens Andersen: Andersen. En biografi 1-2. Gyldendal 2003. 528 s. + 440 s

The spatial and temporal distribution of hantavirus and arenavirus antibody-positive wild rodents in Trentino, Italy, was studied using immunofluorescence assays (IFA) in two long-term sites trapped in 2000–2003, and six other sites trapped in 2002. The overall hantavirus seroprevalence in the bank voles, Clethrionomys glareolus (n=229) screened for Puumala virus (PUUV) antibodies was 0·4%, and that for Apodemus flavicollis mice (n=1416) screened for Dobrava virus (DOBV) antibodies was 0·2%. Antibodies against lymphocytic choriomeningitis virus (LCMV) were found in 82 (5·6%) of the 1472 tested rodents; the seroprevalence being 6·1% in A. flavicollis (n=1181), 3·3% in C. glareolus (n=276), and 14·3% in Microtus arvalis (n=7). Of the serum samples of 488 forestry workers studied by IFA, 12 were LCMV-IgG positive (2·5%) and one DOBV-IgG positive (0·2%), however, the latter could not be confirmed DOBV-specific with a neutralization assay. Our results show a widespread distribution but low prevalence of DOBV in Trentino, and demonstrate that the arenavirus antibodies are a common finding in several other rodent species besides the house mouse.

Abstract. Partitioning carbon fluxes is key to understanding the process underlying ecosystem response to change. This study used soil and canopy fluxes with stable isotopes (13C) and radiocarbon (14C) measurements in an 18 km2, 50-year-old, dry (287 mm mean annual precipitation; nonirrigated) Pinus halepensis forest plantation in Israel to partition the net ecosystem's CO2 flux into gross primary productivity (GPP) and ecosystem respiration (Re) and (with the aid of isotopic measurements) soil respiration flux (Rs) into autotrophic (Rsa), heterotrophic (Rh), and inorganic (Ri) components. On an annual scale, GPP and Re were 655 and 488 g C m−2, respectively, with a net primary productivity (NPP) of 282 g C m−2 and carbon-use efficiency (CUE = NPP ∕ GPP) of 0.43. Rs made up 60 % of the Re and comprised 24±4 %Rsa, 23±4 %Rh, and 13±1 %Ri. The contribution of root and microbial respiration to Re increased during high productivity periods, and inorganic sources were more significant components when the soil water content was low. Comparing the ratio of the respiration components to Re of our mean 2016 values to those of 2003 (mean for 2001–2006) at the same site indicated a decrease in the autotrophic components (roots, foliage, and wood) by about −13 % and an increase in the heterotrophic component (Rh∕Re) by about +18 %, with similar trends for soil respiration (Rsa∕Rs decreasing by −19 % and Rh∕Rs increasing by +8 %, respectively). The soil respiration sensitivity to temperature (Q10) decreased across the same observation period by 36 % and 9 % in the wet and dry periods, respectively. Low rates of soil carbon loss combined with relatively high belowground carbon allocation (i.e., 38 % of canopy CO2 uptake) and low sensitivity to temperature help explain the high soil organic carbon accumulation and the relatively high ecosystem CUE of the dry forest.

Представлена гипотеза о новом механизме ускорения химических реакцийс участием переохлажденной воды вблизи –45 °C. Гипотеза основана на свойствах второйкритической точки воды. Предполагается, что возрастание флуктуации энергии молекулводы приводит к ускорению протекания химических превращений. В эксперименте сиспользованием нанопористых увлажненных силикатных сорбентов удалось наблюдатьреакцию взаимодействия водорода с поверхностью пор при –45 °C. Химические реакциис участием воды по предполагаемому механизму могут ускоренно протекать на линииВидома при температурах от –45 °C до –53 °C и в области давлений от 0 до 100 MPa. ЛИТЕРАТУРА1. Palmer M. Y., Cordiner M. A., Nixon C. A., Charnley S. B., Teanby N. A., Kisiel, Z., Irwin P. G. J., MummaM. J. ALMA detection and astrobiological potential of vinyl cyanide on Titan // Science Advances, 2017,v. 3(7), p. e1700022/6. DOI: https://doi.org/10.1126/sciadv.17000222. Goesmann F., Rosenbauer H., Bredehöft J. 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We propose a novel semiconductor laser structure. It is composed of three cascaded active sections: a Fabry-Pérot laser section sandwiched between two gain-coupled distributed feedback (DFB) laser sections. We have modeled this multi-section structure. The simulation results show that compared with index- and gain-coupled DFB lasers, a significant reduction in the longitudinal spatial-hole burning can be obtained with the proposed device, and that this leads to a stable single longitudinal mode operation at relatively high optical power with a SMSR exceeding 56dB. Full Text: PDF ReferencesL.A. Coldren, "Monolithic tunable diode lasers", IEEE J. Select. Topics Quant. Electron. 6, 988 (2000) CrossRef O. Kjebon, R. Schatz, S. Lourdudoss, S. Nilsson, B. Stalnacke, L. Backbom, "30 GHz direct modulation bandwidth in detuned loaded InGaAsP DBR lasers at 1.55 [micro sign]m wavelength", Electron. Lett. 33(6), 488 (1997). CrossRef N. Kim, J. Shin, E. Sim, C.W. Lee, D.-S. Yee, M.Y. Jeon, Y. Jang, K.H. Park, "Monolithic dual-mode distributed feedback semiconductor laser for tunable continuous-wave terahertz generation", Opt. Expr. 17(16), 13851 (2009). CrossRef M.J. Wallace, R. ORreilly Meehan, R.R Enright, F. Bello, D. Mccloskey, B. Barabadi, E.N. Wang, J.F. Donegan, "Athermal operation of multi-section slotted tunable lasers", Opt. Expr. 25(13), 14426 (2017). CrossRef J.E. Carroll, J.E.A. Whiteaway, R.G.S. Plumb, "Distributed Feedback Semiconductor Lasers", Distributed feedback semiconductor lasers (IEE and SPIE, 1998). CrossRef H. Ghafour-Shiraz, Distributed Feedback Laser Diodes and Optical Tunable Filters (Wiley, 2003). CrossRef D.D. Marcenac, Ph.D dissertation (University of Cambridge, 1993). DirectLink L.M. Zhang, J.E. Carroll, C. Tsang, "Dynamic response of the gain-coupled DFB laser", IEEE J. Quant. Electr. 29, 1722 (1993). CrossRef W. Li, W.-P. Huang, X. Li, J. Hong, "Multiwavelength gain-coupled DFB laser cascade: design modeling and simulation", IEEE J. Quant. Electro. 36(10), 1110 (2000). CrossRef B.M. Mehdi, H. Rachid, in Proc. 3rd Intern. Conf. on Embedded Systems in Telecomm. and Instrument., Annaba, Algeria (2016). DirectLinkC. Henry, "Theory of the linewidth of semiconductor lasers", IEEE J.Quant. Electr. QE-18, 259 (1982). CrossRef K. Takaki, T. Kise, K. Maruyama, N. Yamanaka, M. Funabashi, A. Kasukawa, "Reduced linewidth re-broadening by suppressing longitudinal spatial hole burning in high-power 1.55-/spl mu/m continuous-wave distributed-feedback (CW-DFB) laser diodes", IEEE J. Quant. Electr. 39, 1060 (2003) CrossRef

In the last few decades, the studies in second language acquisition have not answered the question what mechanisms a human’s brain uses to make acquisition of language(s) possible. A neurocognitive model which tries to address SLA from such a perspective was suggested by Ullman (2005; 2015), according to which, “both first and second languages are acquired and processed by well-studied brain systems that are known to subserve particular nonlanguage functions” (Ullman, 2005: 141). The brain systems in question have analogous roles in their language and nonlanguage functions. This article is meant to critically analyse the suggested DP model within the context of neurocognitive studies of L2; and evaluate its contribution to the field of SLA studies. References Aboitiz, F. (1995). Working memory networks and the origin of language areas in the human brain. Medical Hypothesis, 25, 504-506. Aboitiz, F. & Garcia, R. (1977). The anatomy of language revisited. 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Abstract Abstract 2511 Poster Board II-488 Introduction: The signaling mechanisms which orchestrate hematopoietic stem and progenitor cell (HSPC) expansion, and proliferation of leukemic progenitor cells are not fully understood. In vivo parathyroid hormone (PTH) treatment was shown to expand HSPC via activation of bone forming osteoblasts (Calvi et al., Nature, 2003). PTH induced bone remodeling via activation of both osteoblasts and osteoclasts is a basic fibroblast growth factor (bFGF) dependent event (Okada et al., JBC, 2003; Hurley et al., BBRC, 2006). Different FGF receptors are expressed on various sub-types of HSPC and also on bone marrow (BM) stromal cells. This ligand, alone or in combination with other cytokines, promotes ex vivo expansion of both human and murine HSPC. Interestingly, bFGF mediated expansion of HSPC in vitro, in a culture of total BM cells, but not of purified Sca-1+/c-Kit+/Lineage− (SKL) murine HSPC (Yeoh et al., Stem Cells, 2006), implying that HSPC expansion by bFGF is also mediated indirectly via the microenvironment. KG1a is a human CD34+ progenitor AML cell line which harbors a mutation due to a chromosomal translocation, resulting in a constitutively active isoform of the FGF receptor (Gu et al., Blood, 2006). We used this cell line to elucidate the mechanism behind FGF mediated expansion of human CD34+ progenitors. The goal of this study is to reveal the roles of PTH and bFGF in regulation of normal and leukemic HSPC expansion in vivo and the downstream signaling machinery. Results: In order to understand how cytokines control HSPC proliferation and expansion in vivo, we repeatedly injected PTH to wild type (WT) and bFGF knock-out (KO) mice (5 injections per week) for 4 weeks. We observed that PTH administration to WT mice increased the levels of primitive SKL progenitors in the BM and spleen, decreased the percentage of G0 quiescent SKL cells, and upregulated c-Kit expression on the Lin−/Sca-1+ primitive progenitor population. Surprisingly, these effects were not observed in bFGF KO mice treated with PTH, revealing that PTH induced expansion of HSPC requires bFGF signaling. Repeated bFGF injections for only 1 week (total of 7 injections), significantly increased the numbers and frequency of hematopoietic progenitor cells (HPC) with only a minor effect on differentiated white blood cell numbers in the murine BM and spleen. HSPC expansion by bFGF was accompanied with splenomegaly, a phenotype resembling myelo-proliferative like diseases. In addition we found that bFGF downregulated SDF-1 and upregulated SCF expression on BM stromal cells together with upregulation of c-Kit expression on Lin−/Sca-1+ primitive progenitors. Inhibition of FGF signaling in KG1a cells using a specific FGFR inhibitor reduced STAT5 phosphorylation levels and increased the G0 quiescent cell fraction. Moreover, specific inhibitors of FGFR, JAK2 and STAT5, completely blocked human leukemic KG1a proliferation, implying for the involvement of this signaling pathway in expansion of immature human CD34+ AML cells. Conclusions: Our preliminary results reveal that bFGF is down stream of PTH induced HSPC expansion in vivo and that this ligand can expand progenitor cells in their natural BM and spleen microenvironments. bFGF rapidly mediates higher expansion of murine SKL HSPC within 1 week as compared to PTH expansion within 4 weeks. PTH and bFGF induced expansion is mediated both directly and indirectly by upregulating c-Kit receptors on HSPC and its ligand, SCF expression by stromal cells. Our in vitro experiments with malignant human KG1a cells indicate that FGF signaling activates STAT5 via JAK2 to promote expansion of both normal and leukemic progenitor cells. This activation is most probably mediated via SCF/c-Kit signaling since AML cells express high levels of these molecules (Ramenghi et al., Stem Cells, 1994) and therefore may bypass the dependency on the stromal microenvironment. Further studies will provide insights on how PTH/bFGF and their downstream mediators like c-Kit and SCF control normal and leukemic HSPC expansion and their evolving stromal microenvironments. These insights may be used for the development of drugs to inhibit expansion and survival of leukemic HSPC in patients. Moreover, they may also contribute to future development of therapeutic applications aimed at expanding normal HSPC prior to their mobilization or following clinical HSPC transplantation protocols. Disclosures: No relevant conflicts of interest to declare.

Ключові слова: пам’ять, ідентичність, національна ідентичність, комеморація, кмеморативні практики. Анотація Національна ідентичність, з одного боку, є однією з фундаментальних ідентичностей, тобто, вона може служити орієнтиром для людини навіть тоді, коли інші (професійні, родинні, класові) швидко змінюються внаслідок трансформації суспільства. З іншого боку, зміни суспільства, його соціальних інститутів (як агентів впливу) змінюють зміст і форми національної ідентичності членів суспільства. Відтак усталення тієї чи іншої моделі ідентичності здійснюється в певному соціальному контексті, який задає не тільки спектр альтернатив, але й набір різних комеморативних практик. У статті обґрунтовується взаємообумовленість смислоконституювання пам’яттєвого та ідентичнісного дискурсів, із урахуванням того, що пам’яттєвий дискурс, з одного боку, віддзеркалює характерні риси національної ідентичності, а з іншого – формує своєрідну смислову основу останньої, моделює її, впливаючи на зміни з різним ступенем інтенсивності. Доведено, що національна ідентичність формується за допомогою колективної пам’яті та комеморативних практик. Посилання Anderson, 2001 – Anderson B. Voobrazhaemыe soobshchestva. Razmыshlenyia ob ystokakh y rasprostranenyy natsyonalyzma [Imaginary communities. Reflections on the origins and spread of nationalism]. M. : Kanon-press, 2001. 288 s. [in Russian] Assman, 2012 – Assman A. Prostory spohadu. Formy ta transformatsii kulturnoi pam’iati [Spaces of memory . Forms and transformations of cultural memory] / per. z nim. K. Dmytrenko, L. Doronicheva, O. Yudin. K.: Nika-Tsentr, 2012. 440 s. (Seriia «Zmina paradyhmy». Vyp. 15). 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Solar cells based on c-Si/porous-Si/CdS/ZnxCd1-xO heterojunctions were synthesized by depositing CdS films on c-Si/porous-Si (PS) substrates by electrochemical deposition (ED). PS layers with systematically varied pore diameter (8-45 nm) and were fabricated on p-type c-Si wafers using electrochemical etching. The window layers of ZnxCd1-xO with several Zn concentrations(x=0.2; 0.4; 0.5 and 0.6) were also deposited on the CdS buffer layers by ED. The photoelectrical properties of heterojunctions were studied as functions of PS pore size and Zn content in ZnxCd1-xO. The optimal pore size and Zn contents were found to be 10 nm and x=0.6, respectively. These yielded a solar cell sample exhibiting an efficiency of 9.9%, the maximum observed in this study. Full Text: PDF ReferencesM.A.Green. "Limiting efficiency of bulk and thin-film silicon solar cells in the presence of surface recombination", Progress in Photovoltaic 7, 327 (1999). CrossRef P.Papet, O. Nichiporik, A. Kaminski et al. "Pyramidal texturing of silicon solar cell with TMAH chemical anisotropic etching", Solar Energy Materials and Solar Cells 90, 2319 (2006). CrossRef P. Vitanovet et al. "High-efficiency solar cell using a thin porous silicon layer", Thin Solid Films 297, 299 (1997). CrossRef L. Santinacci et al. "Electrochemical and optical characterizations of anodic porous n-InP(1 0 0) layers", Electrochim. Acta 56, 878 (2010). CrossRef V.Lehmann. "The Physics of Macropore Formation in Low Doped n‐Type Silicon", J. Electrochem. Soc. 140, 2836 (1993). CrossRef Bisi O et al. "Porous silicon: a quantum sponge structure for silicon based optoelectronics", Surface Science Reports 38, 1 (2000). CrossRef A.I. Raid et al. Applied Nanoscience 7, 9 (2016). CrossRef M.A. Naser et al. "Characteristics of Nanostructure Silicon Photodiode using Laser Assisted Etching", Procedia Engineering 53, 393 (2013). CrossRef D.H. Oh et al. J. Ceram. Process. Res. "Effects of a H2SO4 treatment on the optical properties in porous Si layers and electrical properties of diode devices fabricated with a H2SO4 treated porous Si layer", 9, 57 (2008). DirectLink H. Foll et al. "Formation and application of porous silicon", Materials Science and Engineering R 280, 1 (2002). CrossRef P. Granitzer et al. "Porous Silicon—A Versatile Host Material", Materials 3, 943 (2010). CrossRef G. Korotcenkov, Porous Silicon: From Formation to Application (Taylor and Francis Group, CRC Press, Boca Raton, USA, 2016). DirectLink V.Y. Yerokhov. "Porous silicon in solar cell structures: a review of achievements and modern directions of further use", Renewable and Sustainable Energy Rev. 3, 291 (1999). CrossRef A. Ramizy et al. "New optical features to enhance solar cell performance based on porous silicon surfaces", Appl. Surf. Science 257, 6112 (2011). CrossRef F. Ruske et al. "Large area ZnO:Al films with tailored light scattering properties for photovoltaic applications", Thin Solid Films 515, 8695 (2007). CrossRef Y. Alivov et al. "Observation of 430 nm electroluminescence from ZnO/GaN heterojunction light-emitting diodes", Appl. Phys. Lett. 83, 2943 (2003). CrossRef G.V. Lashkarev et al. "Properties of zinc oxide at low and moderate temperatures", Low Temp. Phys. 37, 289 (2011). CrossRef P.M. Devshette et al. "Growth and physical properties of ZnxCd1−xO thin films prepared by spray pyrolysis technique", J. of Alloys and Compunds 463, 576 (2008). CrossRef Y. Caglar et al. "Morphological, optical and electrical properties of CdZnO films prepared by sol–gel method", J. Phys. D: Appl. Phys. 42, 065421 (2009). CrossRef A. Abdinov et al. "Photosensitivity of p,n-Si/n-Cd1−xZnxS heterojunctions manufactured by a method of electrochemical deposition", Thin Solid Films 480-481, 388 (2005). CrossRef A Abdinov et al. "Investigation of electrodeposited p-Si/Cd1 − xZnxS1 − ySey heterojunction solar cells", Thin Solid Films 511-512,140 (2006) CrossRef J.B. Orhan et al. "Nano-textured superstrates for thin film silicon solar cells: Status and industrial challenges", Sol. Cells 140, 344 (2015). CrossRef H.Ch. Alan et al. "Light management of tandem solar cells on nanostructured substrates", J. Photon. Energy 7, 027001 (2017) CrossRef

Over 2004–2006, effects of mineral fertilisers (60 N + 30 P + 60 K kg/ha or 120 N + 30 P + 60 K kg/ha) and farmyard manure (12 or 24 t/ha) application on biological and chemical properties of soil were studied in seminatural grassland. The research trial was established at Radvaň site, central Slovakia (altitude 480 m, loamy to sandy-loamy Cambisol). These parameters were investigated during the growing seasons: CO₂ production, intensity of total N mineralisation (TMN), the rate of nitrification (NIT), total C content in microbial biomass (MB-C), C_ox, N_t, P, K, Mg and the humic acids to fulvic acids ratio (HA:FA). At the application of mineral fertilisers, the highest N rate significantly increased TMN and NIT, mainly in 2004 and 2005. The manure application showed the strongest effects on the biological parameters. The manure rate of 12 t/ha significantly increased the soil respiration in 2005 and 2006 as well as TMN and NIT throughout the research. The manure application increased also the soil pH, MB-C, N_t, Mg, P and C_ox.

A new technique called energy-loss magnetic chiral dichroism (EMCD) has recently been developed [P. Schattschneider, et al. Nature441, 486 (2006)] to measure magnetic circular dichroism in the transmission electron microscope (TEM) with a spatial resolution of 10 nm. This novel technique is the TEM counterpart of x-ray magnetic circular dichroism, which is widely used for the characterization of magnetic materials with synchrotron radiation. In this paper we describe several experimental methods that can be used to measure the EMCD signal [P. Schattschneider, et al. Nature441, 486 (2006); C. Hébert, et al. Ultramicroscopy108(3), 277 (2008); B. Warot-Fonrose, et al. Ultramicroscopy108(5), 393 (2008); L. Calmels, et al. Phys. Rev. B76, 060409 (2007); P. van Aken, et al. Microsc. Microanal.13(3), 426 (2007)] and give a review of the recent improvements of this new investigation tool. The dependence of the EMCD on several experimental conditions (such as thickness, relative orientation of beam and sample, collection and convergence angle) is investigated in the transition metals iron, cobalt, and nickel. Different scattering geometries are illustrated; their advantages and disadvantages are detailed, together with current limitations. The next realistic perspectives of this technique consist of measuring atomic specific magnetic moments, using suitable spin and orbital sum rules, [L. Calmels, et al. Phys. Rev. B76, 060409 (2007); J. Rusz, et al. Phys. Rev. B76, 060408 (2007)] with a resolution down to 2 to 3 nm.

In this contribution, a numerical study of the optical properties of closely-packed gold nanorods was performed. The studied nano-objects are experimentally grown on a tilted polydimethylsiloxane (PDMS) substrate by using physical vapor deposition (PVD). This method creates nanorods tilted to a certain angle with respect to the substrate normal. This geometry allows exciting both transverse and longitudinal modes of the rods. As demonstrated in a previous experimental work, such PVD-grown nano-objects show promising possibilities both as strain gauges or strain-tunable metamaterials if fabricated on a stretchable dielectric substrate. This numerical study is based on experimental data from previous work and pushes further the subject by approaching an optimized nano-structure allowing better strain-sensitivity (particularly by changing the auto-organization of the said nanorods). Full Text: PDF ReferencesJ.W.M. Chon, C. Bullen, P. Zijlstra, M. Gu, "Spectral encoding on Gold Nanorods Doped in a Silica Sol?Gel Matrix and Its Application to High-Density Optical Data Storage", Adv. Funct. Mater. 17, 875 (2007). CrossRef C.-C. Chen, Y.-P. Lin, C.-W. Wang, H.-C. Tzeng, C.-H. Wu, Y.-C. Chen, C.-P. Chen, L.-C. Chen, Y.-C. Wu, "DNA?Gold Nanorod Conjugates for Remote Control of Localized Gene Expression by near Infrared Irradiation", J. Am. Chem. Soc. 128, 3709 (2006). CrossRef J.N. Anker, W.P. Hall, O. Lyandres, N.C. Shah, J. Zhao, R.P. Van Duyne, "Biosensing with plasmonic nanosensors", Nat. Mater 7, 442 (2008). CrossRef B. Sepulveda, P.C. Angelome, L.M. Lechuga, L.M. Liz-Marzan?, "LSPR-based nanobiosensors", Nano Today 4, 244 (2009). CrossRef A. Haes, R.P. Van Duyne, "A Nanoscale Optical Biosensor: Sensitivity and Selectivity of an Approach Based on the Localized Surface Plasmon Resonance Spectroscopy of Triangular Silver Nanoparticles", J. Am. Chem. Soc. 124, 10596 (2002). CrossRef J.C. Riboh, A.J. Haes, A.D. McFarland, C.R. Yonzon, R.P. Van Duyne, "A Nanoscale Optical Biosensor: Real-Time Immunoassay in Physiological Buffer Enabled by Improved Nanoparticle Adhesion", J. Phys. Chem. B 107, 1772 (2003). CrossRef C.R. Yonzon, E. Jeoung, S. Zou, G.C. Schatz, M. Mrksich, R.P. Van Duyne, "A Comparative Analysis of Localized and Propagating Surface Plasmon Resonance Sensors: The Binding of Concanavalin A to a Monosaccharide Functionalized Self-Assembled Monolayer", J. Am. Chem. Soc. 126, 12669 (2004). CrossRef A.J. Haes, L. Chang, W.L. Klein, R.P. Van Duyne, "Detection of a Biomarker for Alzheimer's Disease from Synthetic and Clinical Samples Using a Nanoscale Optical Biosensor", J. Am. Chem. Soc. 127, 2264 (2005). CrossRef R. Caputo, G. Palermo, M.Infusino L. De Sio, "Liquid Crystals as an Active Medium: Novel Possibilities in Plasmonics", Nanospectroscopy 1, 40 (2015). CrossRef T. Maurer, J. Marae-Djouda, U. Cataldi, A. Gontier, G. Montay, Y. Madi, B. Panicaud, D. Macias, P.-M. Adam, G. Lév?que, T. Bürgi, R. Caputo, "The beginnings of plasmomechanics: towards plasmonic strain sensors", Frontiers of Materials Science 9, 170 (2015). CrossRef X. Niu, S. P. Stagon, H. Huang, J.K. Baldwin, A. Misra, "Smallest Metallic Nanorods Using Physical Vapor Deposition", Phys. Rev. Lett. 110 136102 (2013). CrossRef Lumerical Solutions, Inc. DirectLink P.K. Jain, W. Huang, M.A.El-Sayed, "On the Universal Scaling Behavior of the Distance Decay of Plasmon Coupling in Metal Nanoparticle Pairs: A Plasmon Ruler Equation", Nanoletters 7, 2080 (2007). CrossRef P.K. Jain, M.A. El-Sayed, "Plasmonic coupling in noble metal nanostructures", Chem. Phys. Letters 487, 153 (2010). CrossRef

Candidemia is becoming more actual because of better survival of even critically ill patients, wide use of antimicrobials, and increased numbers of invasive procedures and manipulations. Diagnosis of candidemia remains complicated, and costs of treatment and mortality rates are increasing. Objective. To evaluate the pathogens of candidemia, risk factors and their influence on outcome. Material and methods. Data of 41 patients with positive blood culture for Candida spp., who were treated in the intensive care units at the Hospital of Kaunas University of Medicine, were analyzed retrospectively. Results. Candidemia was caused by Candida albicans (C. albicans) in 48.8% (n=20) of patients and by non-albicans Candida in 51.2% (n=21) of patients. The main cause of candidemia was C. albicans in 2004 (83.3%, n=5), but in 2005 (63.6%, n=7), in 2006 (57.1%, n=4), and in 2007 (52.9%, n=9), the main cause was non-albicans Candida spp. The number of candidemia cases caused by C. albicans was decreased in 2005, 2006, and 2007 as compared with 2004, and the number of candidemia caused by non-albicans Candida spp. was decreased, respectively (P<0.05). More than 65% (n=34) of patients had severe disease (P<0.05). Lethal outcome was recorded in 58.5% of patients with candidemia. Mechanical ventilation was used in 76.9% (n=20) and urinary bladder catheter in 72.1% (n=19) of non-survivors and in 23.1% (n=6) and 26.9% (n=7) of survivors, respectively (P<0.05). Conclusions. There is an increase in the prevalence of candidemia in the intensive care units during the 4-year period; half of candidemia cases were caused by non-albicans Candida spp., and patients with candidemia caused by non-albicans Candida spp. are at higher risk of mortality. Therefore, for the empirical treatment of septic conditions in an intensive care unit, when invasive fungal infection is suspected, we recommend using an antifungal agent of non-azole class until a pathogen of candidemia is determined. Severe disease is evaluated as a risk factor for candidemia. Patients with oncological diseases are at significantly higher risk for candidemia caused by non-albicans Candida spp. Use of mechanical ventilation and urinary bladder catheter is a risk factor for lethal outcome.

Sweet potato feathery mottle virus (SPFMV), Sweet potato virus G (SPVG), and Sweet potato virus 2 (SPV2) (also known as Ipomoea vein mosaic virus (2) and Sweet potato virus Y) are members of the genus Potyvirus (family Potyviridae), which can synergistically interact with Sweet potato chlorotic stunt virus (SPCSV; genus Crinivirus, family Closteroviridae), increasing symptom severity on sweet potato (Ipomoea batatas (L.) Lam.) (1,2,3). During 2002, 2006, and 2007, vine cuttings from sweet potato plants were collected in Malaga (southern Spain), Tenerife, and Lanzarote (Canary Islands, Spain) to be tested for the presence of viruses. Sampled plants ranged from asymptomatic to severely affected by symptoms of sweet potato virus disease (SPVD), caused by dual infection with SPFMV or other potyviruses with SPCSV. Scions collected during 2002 were grafted to the indicator host I. setosa. Foliar samples from I. setosa were used for nitrocellulose membrane (NCM)-ELISA testing with antisera specific to SPVG or SPV2 (provided by C. A. Clark, Louisiana State University) following described procedures (2). NCM-ELISA testing indicated that SPVG was present in samples from Malaga, Tenerife, and Lanzarote, whereas SPV2 was only found in samples from Malaga. Reverse-transcription (RT)-PCR was performed on RNA extracts from sweet potato or I. setosa leaves using primer pairs MA541 (5′-AACAATTCCAGATAGTAGAGGGGTTG-3′)/MA542(5′-TGTGGGGACAGCATGATCCAATAG-3′) and MA540 (5′-AACCCCAACACCAGCAAAATCAGTTAAG-3′)/MA542 corresponding to the capsid protein (CP) genes of SPVG and SPV2, respectively. Thirteen of 47 samples from Malaga and 4 of 30 from the Canary Islands yielded the expected 483-bp DNA fragment with the primers for SPVG. Fifteen of 47 samples from Malaga yielded the expected 627-bp DNA fragment with primers for SPV2. Two RT-PCR amplicons of SPVG, one from Malaga and one from Tenerife, were sequenced. Their nucleotide sequences (GenBank Accession Nos. EF577438 and EF577439, respectively) showed 98% identity to SPVG isolates from Louisiana (2) and China. Sequencing of one RT-PCR amplicon of SPV2 from Malaga resulted in a nucleotide sequence (GenBank Accession No. EF577437) with 99% identity to SPV2 from Lousiana and Australia (3). The presence of SPVG and SPV2 increases the already existing risk of SPVD, since the main viruses involved in the synergism, SPFMV and SPCSV, are present in Spain (4). SPCSV was also detected in some of the plants infected with SPVG or SPV2, in some cases, in coinfection with SPFMV. References: (1) C. D. Kokkinos and C. A. Clark. Plant Dis. 90:1347, 2006. (2) E. R. Souto et al. Plant Dis. 87:1226, 2003. (3) F. Tairo et al. Plant Dis. 90:1120, 2006. (4) R. A. Valverde et al. Plant Dis. 88:428, 2004.

Can Gio mangrove forest (CGM) is located downstream of Ho Chi Minh City (HCMC), situated between an estuarine system of Dong Nai - Sai Gon river and a part of Vam Co river. The CGM is the largest restored mangrove forest in Vietnam and the UNESCO’s Mangrove Biosphere Reserve. The CGM has been gradually facing to numeric challenges of global climate change, environmental degradation and socio-economic development for the last decades. To evaluate sediment quality in the CGM, we collected 13 cores to analyze for sediment grain size, organic matter content, and trace element concentration of Cd, Cr, Cu, Ni, Pb, Zn. Results showed that trace element concentrations ranged from uncontaminated (Cd, Cu, and Zn) to very minor contaminated (Cr, Ni, and Pb). The concentrations were gradually influenced by suspended particle size and the mangrove plants.ReferencesAnh M.T., Chi D.H., Vinh N.N., Loan T.T., Triet L.M., Slootenb K.B.-V., Tarradellas J., 2003. 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Aune, D E 2006. Apocalypticism, Prophecy and Magic in Early Christianity: Collected Essays. Tübingen: Mohr Siebeck. (WUNT 199). Pp. xii + 482. Price: 100 €. ISBN 3-16-149020-7.Brownson, J V 2007. The Promise of Baptism. An introduction to Baptism in Scripture and the Reformed Tradition. Grand Rapids, MI/Cambridge, U.K.: William B. Eerdmans Publishing Company. Pp. 223. Price: $16-00. ISBN: 978-0-8028-3307.Buchholz, Armin. Schrift Gottes im Lehrstreit: Luthers Schriftverständnis und Schriftauslegung in seinen drei großen Lehrstreitigkeiten der Jahre 1521-1528, TVG Systematisch-Theologische Monografien (STM) 20 (Gießen: Brunnen, 2007). Paperback, 340 S. ISBN 978-3-7655-9549-3. Price: 30 €Helmer, C (ed) 2005. Biblical Interpretation: History, Context and Reality. Leiden: Brill. ISBN: 9004130748. Price: €80-00.Koch, H 2006. Die Kirchen und ihre Tabus. Die Verweigerung der Moderne. Düsseldorf: Patmos. Pp. 230. Hard cover. ISBN 3-491-72498-8. Price: €18-00.

AbstractExtending the idea of Dabrowski [‘On the proportion of rank 0 twists of elliptic curves’, C. R. Acad. Sci. Paris, Ser. I 346 (2008), 483–486] and using the 2-descent method, we provide three general families of elliptic curves over $\mathbb{Q}$ such that a positive proportion of prime-twists of such elliptic curves have rank zero simultaneously.

ASTIER, Marta.; MASERA, Omar.; Galván-Miyoshi, Coord. Evaluatión de Sustentabilidad: Un enfoque dinámico y multidimensional. SEAE/CIGA/ECOSUR/CIEco/UNAM/GIRA/Mundiprensa/ Fundación Instituto de Agricultura Ecológica y Sustentable, Espanha, 2008.ALMEIDA, Rozemberg, Ribeiro: Escravidão de quilombos na Amazônia: Jacaraquara em pauta – Natal – Rn. 22 a 26 de julho de 2013.BARRETO, Jônatas. Dissertação de Mestrado, Programa de Pós-graduação em Arquitetura e Urbanismo, Implantação de infraestrutura habitacional em comunidades tradicionais: o caso da comunidade quilombola Kalunga. Universidade de Brasília, Brasília, DF. N. (2006). 37p.BARROS, Maria. Theodora. Paiva., Agricultura Familiar. O processo de formação para a sustentabilidade na comunidade de Marupaúba, Município de Tomé – Açu, PA. Belém, Pará, 2010. Brasil: 184p.FARIAS, Emanuel, Almeida. Quilombola na Amazônia: um esboço preliminar do estudo de comunidades de pretos no complexo Madeira. 2007.FONSECA, Alex, Sandro. Santos., Entre territórios: Políticas Públicas e Comunidades Tradicionais. Anais eletrônicos do XXII. Encontro Estadual de história da ANPHH – SP. Santos. 2014.FILHO, Flávio, Ferreira, Lisboa, SILVA, Thomas, Josué. Cultura e identidade: subjetividade e minorias sociais – Santa Maria, RS: UFSM, 2018.FURTADO, Marcela, Brasil; SUCUPIRA, Regina, Lúcia; ALVES, Beatriz,Cultura, identidade e subjetividade Quilombola: Uma leitura a partir da psicologia cultural. V.26 n°1. Belo Horizonte jan/abril 2014.GARCIA, Denise. Schmitt. Siqueira., A atividade portuária como garantidora do Princípio da sustentabilidade. Revista Direito Econômico Socioambiental. Curitiba, v. 3, n. 2, p. 375-399, jul/dez. 2012.GARCIA, Denise, SCHMITT, Siqueira. Dimensão Econômica da Sustentabilidade: uma análise com base na economia verde e a teoria do crescimento. Veredas do direito, Belo Horizonte, V. 13 n° 25 p. 133 – 153. Janeiro/ abril de 2016.GEHLEN, Ivaldo., Políticas públicas e desenvolvimento social rural. São Paulo perspec. Vol. 18 N° 2. São Paulo. June, 2004.GOMES, Flavio dos Santos. Quilombos e Mocambos no Brasil (Sécs. XVII-XIX). 1997 (Tese de Doutorado). Campinas: Universidade de Campinas, 1997.HOMMA, Alfredo. Imigração Japonesa na Amazônia: Sua Contribuição para o Desenvolvimento Agrícola. Belém: EMBRAPA Amazônia Oriental, 2007.HOMMA, Alfredo. et al. Bases para uma política de desenvolvimento da cultura do dendê na Amazônia. 2000. p. 11-30.LEFF, Enrique. Saber Ambiental. Sustentabilidade, racionalidade, complexidade e poder. Tradução de Lúcia Mathilde Endlich Orth. 8. ed. Petrópolis, RJ: Vozes, 2011.MASERA; Omar; ASTIER, Marta; LÓPEZ- RIDAURA, Santiago. Sustentabilidad y manejo de recursos naturales: el marco de evalución mesmes. México: Mundi – prensa, 2000, p.22MELLO, N. A. E a política agrícola transforma-se em instrumento do desenvolvimento sustentável. Rev. NERA, ano 11, n. 12 p. 68-85, jan./jun. 2008.MORAES; Luiz, Duarte; AMÂNCIO, Cristhiane, Oliveira, Graça; RESENDE; Alexander, Silva. Sistemas agroflorestais para o uso sustentável do solo: Considerações agroecológicas e socioeconômicas. Embrapa agrobiologia. Rio de Janeiro – 2001.MUTO, Reiko., O Japão na Amazônia. Condicionates para fixação e mobilidade dos imigrantes japoneses. (1929 – 2009). Belém, 2010.NAHUM, J. S; BASTOS, C. S. Dendeicultura e descampesinização na Amazônia paraense. In: CAMPO-TERRITÓRIO: revista de geografia agrária, v. 9, n. 17, p. 469-485, abr., 2014. Disponível em: <http://www.seer.ufu.br/index.php/campoterritorio/issue/view/1113>. Acesso em: 28/10/2019.OLIVEIRA, Aberlene, Ribeiro, PINTO, Josefa, Eliane, Santana. As transformações no campo e o modo de vida Camponês (des) territorialidade no munícipio de Poço Verde/ SE. Ateliê geográfico – Goiânia – v.7, n.1, abril 197 - 214, 2013.PAULA, Helga. Maria. Martins.; TÁRREGA, Vidotte. Blanco. A importância das comunidades tradicionais para a justiça ambiental e o desenvolvimento sustentável. In: VI Congresso de Meio Ambiente da AUGM, 2009, São Carlos. VI Congresso de Meio Ambiente da AUGM, 2009.PACHÊCO, Nilza. Araújo.; Matos, T. X. Boletim agrometeorológico 2005 - Tome-Açú. Belém: Embrapa Amazônia Oriental, 2006, p.35. Embrapa Amazônia Oriental Documentos 277.patentes.PLOEG, Jan. Dowe. Van Der. O modo de produção Camponês revisitado. Agricultura familiar e desenvolvimento rural – Porto Alegre. 24 e 25 de Novembro, 2005.REIS. Cleoson.; PEREIRA, Priscila. Rollo. Diagnóstico de Desenvolvimento Rural da Comunidade de Santa Luzia no Município de Tomé-Açu, Nordeste Paraense. Monografia de Estágio Supervisionado. Castanhal, Pará. 2014.RODRIGUES, Tarcísio. Ewerton. et al. Zoneamento agroecológico do município de Tomé-Açu, Estado do Pará. Belém: Embrapa Amazônia Oriental, 2001. 81p. Embrapa Amazônia Oriental Documentos n. 118.

При проведении в водном объекте гидротехнических работ, связанных с изъятием или отвалом донного грунта, возникают зоны повышенной мутности. Повышенная концентрация взвешенных веществ в реке или водоёме может привести к отрицательным последствиям, таким как ухудшение качества воды, нежелательным изменениям глубин, нарушением экологического режима водного объекта. Основными количественными характеристиками полей повышенной мутности, как следствия дноуглубительных работ и дампинга, являются геометрические размеры и продолжительность стояния облака повышенной мутности в водных объектах с замедленным водообменом, интенсивность распространения шлейфов повышенной мутности в акватории, концентрация взвешенных веществ на разном удалении от источника взмучивания и так далее. Определенный интерес может представлять оценка гидродинамического потенциала максимального содержания взвешенных веществ в потоке вне зоны влияния действующего источника техногенного взмучивания, то есть максимальной вместимости водным потоком взвешенных частиц или иначе транспортирующей способности потока. Особенную ценность такие построения представляют для меженного периода, характеризующегося наименьшей глубиной потока, а значит наибольшими значениями мутности. Полученное поле максимального насыщения водных масс взвешенными веществами при гипотетической инициации процессов взмучивания донного грунта позволит оценить области акватории с наиболее неблагоприятными возможными значениями мутности воды, что может стать основой для последующих рекомендаций по мероприятиям, связанным с дноуглубительными работами и дампинге. Оценка гидродинамического потенциала максимального содержания взвешенных веществ в потоке для однородной части акватории водоёма в данной работе проводится по известным формулам транспортирующей способности потока. Построение поля максимально возможных концентраций взвешенных веществ осуществляется в результате совместной реализации системы гидродинамических уравнений и формулы транспортирующей способности потока. Библиографические ссылки 1. Ботвинков В.М., Дегтярев В.В., Седых В.А. Гидроэкология на внутренних водных путях. Новосибирск: Сибирское соглашение, 2002. 356 с. 2. ВРДС 12-05-03 МО РФ. Методические указания по расчёту распространения зон мутности при дноуглублении и дампинге на акваториях ВМФ. М., 2003. 80 с. 3. Временные указания по оценке повышения мутности при землечерпательных работах, проводимых для обеспечения транзитного судоходства на реках и учету ее влияния на качество воды и экологию гидробионтов. М.: МРФ РСФСР, 1986. 59 c. 4. Зиновьев Е.А., Китаев А.Б. О воздействии взвешенных частиц на гидрофауну // Известия Самарского научного центра РАН. 2015. Т. 17, №5. С. 283–288. 5. Клеванный К.А., Смирнова Е.В., Шавыкин А.А., Ващенко П.С. Распространение взвеси и ее воздействие на биоту при дноуглублении в Кольском заливе (Баренцево море). 1. Исходные данные и используемые модели // Защита окружающей среды в нефтегазовом комплексе. 2013. №3. С. 18‒24. 6. Кондратьева Т.А., Захаров С.Д., Халиуллина Л.Ю. Влияние добычи нерудных строительных материалов на экосистемы Куйбышевского водохранилища // Вестник Казанского технологического университета. 2012. Т. 15, №19. С. 116–119. 7. Лепихин А.П., Головачева С.И. К проблеме регламентации отведения взвешенных веществ в естественные водотоки // Водное хозяйство России: проблемы, технологии, управление. 2015. №1. С. 4–13. 8. Максимова О.Б. Оценка влияния повышенной мутности воды, возникающей при проведении гидротехнических работ, на структурно-функциональные характеристики фитопланктона: Дис. ... канд. биол. наук. СПб, 2002. 182 с. 9. Методика расчёта дополнительной мутности и вторичного загрязнения вод при производстве дноуглубительных работ и добычи НСМ на реках и водоѐмах. Министерство речного флота РСФСР. Ленгипроречтранс, 1990. 18 с. 10. Методические основы оценки и регламентирования антропогенного влияния на качество поверхностных вод / Под ред. А.В. Караушева. Л.: Гидрометеоиздат, 1987. 285 с. 11. Понкратов С.Ф. Определение зоны мутности при выемке и перемещении грунта в руслах крупных рек // Сборник научных трудов ГосНИОРХ. 1989. Вып. 296. С. 148‒156. 12. Рахуба А.В. Опыт использования измерительно-вычислительной системы «Хитон Волна» в гидроэкологических исследованиях прибрежной акватории г. Тольятти // Экологические проблемы промышленных городов / Сборник 8-й Международной научно-практической конференции. Саратов, 2017. С. 484‒488. 13. СТО ФГБУ «ГГИ» 52.08.31‒2012. Добыча нерудных строительных материалов в водных объектах. Учет руслового процесса и рекомендации по проектированию и эксплуатации русловых карьеров. СПб: Изд-во «Глобус», 2012. 140 с. 14. Типовая технологическая схема добычи песка, гравия, песчано-гравийной смеси в руслах судоходных рек и других судоходных водоёмах. М.: МРФ РСФСР. Главное управление портов, 1980. 58 с. 15. Шмакова М.В. Расчёты твердого стока рек и заиления водохранилищ. СПб: Изд-во «ВВМ», 2018. 149 с.

Heterojunctions of p-Si/Cd1-xZnxO were synthesized by depositing of Cd1-xZnxO films on p-Si substrates by electrochemical deposition. The morphological properties of the films were studied by scanning microscopy. The electric and photoelectrical properties of heterojunctions were investigated depending on the deposition potential and films composition. Heterojunctions of p-Si/Cd1-xZnxO, which deposited at cathode potential of -1.2 V, shows good rectification (k=1640). Under AM1.5 conditions the maximal values of open-circuit voltage, short-circuit current, fill factor and efficiency of our best nano-structured cell, were Uoc = 442 mV, Jsc = 19.9 mA/cm2, FF = 0.59 and n = 5.1 %, respectively. Full Text: PDF ReferencesX. Li, et al. "Role of donor defects in enhancing ferromagnetism of Cu-doped ZnO films", J. Appl. Phys., 105, 103914 (2009). CrossRef X. Han, K. Han and M. Tao, "Electrodeposition of Group-IIIA Doped ZnO as a Transparent Conductive Oxide", ECS Trans., 25, 93 (2010). CrossRef W. Liu et al. "Na-Doped p-Type ZnO Microwires", J. Am. Chem. Soc., 132, 2498 (2010). CrossRef R.A. Ismail and O.A. Abdulrazaq, "A new route for fabricating CdO/c-Si heterojunction solar cells", Sol. Energy Mater. Sol. Cells, 91, 903 (2007). CrossRef R.S. Mane, H.M. Pathan, C.D. Lokhande and S.H.Han, "An effective use of nanocrystalline CdO thin films in dye-sensitized solar cells", Sol. Energy, 80 185 (2006). CrossRef E. Martin et al. "Properties of multilayer transparent conducting oxide films", Thin Solid Films, 461, 309 (2004). CrossRef Y. Caglar, M. Caglar, S. Ilican and A. Ates, "Morphological, optical and electrical properties of CdZnO films prepared by sol?gel method", J. Phys. D: Appl. Phys., 42, 065421 (2009). CrossRef F. Wang, Z. Ye, D. Ma, L. Zhu and F. Zhuge, "Formation of quasi-aligned ZnCdO nanorods and nanoneedles", J. Cryst. Growth, 283, 373 (2005). CrossRef A. Abdinov, H. Mamedov, S. Amirova, "Investigation of Electrodeposited Glass/SnO2/CuInSe2/Cd1-xZnxS1-ySey/ZnO Thin Solar Cells", Jpn. J. Appl. Phys., 46, 7359 (2007). CrossRef A. Abdinov, H. Mamedov, H. Hasanov, and S. Amirova, "Photosensitivity of p,n-Si/n-Cd1?xZnxS heterojunctions manufactured by a method of electrochemical deposition", Thin Solid Films, 480-481, 388 (2005). CrossRef A. Abdinov, H. Mamedov, and S. Amirova, "Investigation of electrodeposited p-Si/Cd1 ? xZnxS1 ? ySey heterojunction solar cells", Thin Solid Films, 511-512, 140 (2006) CrossRef H. Mamedov, V. Mamedov, V. Mamedova, Kh. Ahmadova, "Investigation of p-GaAs/n-Cd1-xZnxS1-yTey/Cd1-xZnxO heterojunctions deposited by electrochemical deposition", J. Optoelectrom. Adv. M., 17, 67 (2015). DirectLink H. Mamedov et al. "Preparation and Investigation of p-GaAs/n-Cd1-xZnxS1-yTey Heterojunctions Deposited by Electrochemical Deposition", J. Solar Energy Engineering, 136, 044503 (2014). CrossRef S. Sadofev, S. Blumstengel, J. Cui, J. Puls, S. Rogaschewski, P. Schafer and F. Henneberger, "Visible band-gap ZnCdO heterostructures grown by molecular beam epitaxy", Appl. Phys. Lett., 89, 201907 (2006). CrossRef G. Torres-Delgado et al. "Percolation Mechanism and Characterization of (CdO)y(ZnO)1?y Thin Films", Adv. Funct. Mater., 12, 129 (2002). CrossRef H. Tabet-Derraz, N. Benramdane, D. Nacer, A. Bouzidi and M. Medles, "Investigations on ZnxCd1?xO thin films obtained by spray pyrolysis", Sol. Energy Mater. Sol. Cells, 73, 249 (2002). CrossRef M. Tortosa, M. Mollar and B. Mar?, "Synthesis of ZnCdO thin films by electrodeposition", J. Cryst. Growth, 304, 97 (2007). CrossRef A. Singh, D. Kumar, P. K. Khanna, M. Kumar, and B. Prasad, "Phase Segregation Limit in ZnCdO Thin Films Deposited by Sol?Gel Method: A Study of Structural, Optical and Electrical Properties", ECS Journal of Solid State Science and Technology, 2 (9), Q136 (2013). CrossRef F.Z. Bedia, A. Bedia, B. Benyoucef and S.Hamzaoui, "Electrical Characterization of n-ZnO/p-Si Heterojunction Prepared by Spray Pyrolysis Technique", Physics Procedia, 55, 61 (2014). CrossRef M. Jing-Jing et al. "Rectifying and Photovoltage Properties of ZnO:A1/p-Si Heterojunction", Chin. Phys. Lett., 27 (10), 107304 (2010). CrossRef

Работа направлена на установление закономерностей изменения сдвиговой упругости, возникающих при структурной релаксации металлических стекол на основе Pd и Zr. Измерения модуля сдвига выполнялись на частотах около 500 кГц. Несмотря на отличия в физических свойствах исследованных металлических стекол (химический состав, стеклообразующая способность, температуры стеклования и др.), наблюдаются определенные общие закономерности релаксации их сдвиговой упругости при термообработке. ИСТОЧНИК ФИНАНСИРОВАНИЯ Работа поддержана грантом Минобрнауки РФ № 3.1310.2017/4.6. БЛАГОДАРНОСТИ Автор выражает благодарность проф. В.А. Хонику за обсуждение статьи ЛИТЕРАТУРА Dyre С. Reviews of Modern Physics, 2006, vol. 78, pp. 953–972. https://doi.org/10.1103/revmodphys.78.953 Dyre J. C., Olsen N. B., Christensen T. Physical Review B, 1996, vol. 53, pp. 2171–2174. https://doi.org/10.1103/physrevb.53.2171 Khonik V. A., Mitrofanov Yu. P., Lyakhov S. A., Vasiliev A. N., Khonik S. V., Khoviv D. A. Physical Review B, 2009, vol. 79, pp. 132204-1–132204-4. https://doi.org/10.1103/physrevb.79.132204 Chen H. S. Reports on Progress in Physics, 1980, vol. 43, pp. 353–432. https://doi.org/10.1088/0034-4885/43/4/001 Hirao M., Ogi H. EMATS for Science and Industry: Noncontacting Ultrasonic Measurements. New-York, Springer, 2003, p. 372. Vasil'ev A. N., Buchel'nikov V. D., Gurevich M. I., Kaganov M. I., Gajdukov Ju. P. Electromagnetic Excitation of Sound in Metals. Cheljabinsk, Izd-vo JuUrGU Publ., 2001, 339 p. Wang W. H. Progress in Materials Science, 2012, vol. 57, pp. 487–656. https://doi.org/10.1016/j.pmatsci.2011.07.001 Watanabe L. Y., Roberts S. N., Baca N., Wiest A., Garrett S. J., Conner R. D. Materials Science and Engineering: C, 2013, vol. 33, pp. 4021–4025. https://doi.org/10.1016/j.msec.2013.05.044 Wang D. P., Zhao D. Q., Ding D. W., Bai H. Y., Wang W. H. Journal of Applied Physics, 2014, vol. 115, pp. 123507-1–123507-4. https://doi.org/10.1063/1.4869548 Zhang Z., Keppens V., Liaw P. K., Yokoyama Y. Journal of Materials Research, 2006, vol. 22, pp. 364–367. https://doi.org/10.1557/jmr.2007.0040 Khonik V. A. Izvestija Akademii Nauk. Serija fizicheskaja [Bulletin of the Russian Academy of Sciences: Physics], 2001, vol. 65, no. 10, pp. 1465–1471. (in Russ.) Shtremel' M. A. The Strength of the Alloys. Part Defects of the Lattice. Moscow, MISIS Publ., 1999, 384 p. (in Russ.) Gordon C. A., Granato A. V. Materials Science and Engineering A, 2004, vol. 370, pp. 83–87. https://doi.org/10.1016/j.msea.2003.08.077 Shen T. D., Schwarz R. B. Applied Physics Letters, 2006, vol. 88, pp. 091903-1–091903-3. https://doi.org/10.1063/1.2172160 Tsyplakov A. N., Mitrofanov Yu. P., Khonik V. A., Kobelev N. P., Kaloyan A. A. Journal of Alloys and Compounds, 2015, vol. 618, pp. 449–454. https://doi.org/10.1016/j.jallcom.2014.08.198 Mitrofanov Y. P., Wang D. P., Makarov A. S., Wang W. H., Khonik V. A. // Scientific Reports, 2016, vol. 6, p. 23026-1–23026-6. https://doi.org/10.1038/srep23026 Afonin G. V., Mitrofanov Yu. P., Makarov A. S., Kobelev N. P., Khonik V. A. // Journal of Non-Crystalline Solids, 2017, vol. 475, pp. 48–52. https://doi.org/10.1016/j.jnoncrysol.2017.08.029

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Исследование внутривидовой изменчивости трех функциональных признаков листьев: площади – LA, сухой массы – LDW и удельной площади – SLA показало их взаимообусловленность и зависимость значений признаков от благопритяности условий местообитания и антропогенной нагрузки. Анализ полученных данных исследования показал, что универсальные информационные показатели LA и LDW являются низкими в неблагоприятных и низкопродуктивных местообитаниях и более высокими при изобилии ресурсов в более продуктивных условиях существования. Полученные значения SLA видов растений, произрастающих в сообществах интенсивно эксплуатируемых пастбищ, часто имеют более высокие значения. Возможно, адаптация в условиях постоянного изъятия биомассы на сенокосах и пастбищах идет в первую очередь через сокращение массы листьев при сохранении листовой поверхности. 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Gold nanoparticles (GNPs) have proven to be good nano-sources of heat in the presence of specific electromagnetic radiation. This process, in fact, becomes strongly enhanced under plasmon resonance. In particular, the amount of generated heat and the consequent temperature increase depend on the number of GNPs that are collectively excited and on their relative distance. As a result, the regime of heat localization is deeply controlled by this last parameter. Full Text: PDF ReferencesHutter, E., and Fendler, J. H. "Exploitation of localized surface plasmon resonance". Advanced Materials 16.19, 1685-1706 (2004) CrossRef Liz-Marzán, L. M., Murphy, C. J., & Wang, J. "Nanoplasmonics". Chemical Society Reviews, 43(11), 3820-3822 (2014). CrossRef Maier, S. A. "Plasmonics: fundamentals and applications". Springer Science & Business Media (2007). CrossRef Palpant, B. "Photothermal properties of gold nanoparticles. Gold nanoparticles in physics, chemistry and biology". Imperial College Press, London, (2012). DirectLink Baffou, G. and Quidant R. "Thermo-plasmonics: using metallic nanostructures as nanosources of heat". Laser & Photonics Reviews, 7(2):171?187, (2013). CrossRef Pelton, M., Aizpurua, J., & Bryant, G. "Metal?nanoparticle plasmonics". Laser & Photonics Reviews, 2(3), 136-159 (2008). CrossRef Kreibig, U., & Vollmer, M. "Optical properties of metal clusters" (Vol. 25). Springer Science & Business Media (2013). DirectLink J., Prashant K., S. Eustis, and M. A. El-Sayed. "Plasmon coupling in nanorod assemblies: optical absorption, discrete dipole approximation simulation, and exciton-coupling model." The Journal of Physical Chemistry B 110 (37) 18243-18253 (2006). CrossRef Jain, P. K., & El-Sayed, M. A. "Surface plasmon coupling and its universal size scaling in metal nanostructures of complex geometry: elongated particle pairs and nanosphere trimmers". The Journal of Physical Chemistry C, 112(13), 4954-4960 (2008). CrossRef Chapuis, P. O., Laroche, M., Volz, S., & Greffet, J. J. "Radiative heat transfer between metallic nanoparticles". Applied Physics Letters, 92(20), 201906 (2008). CrossRef Jain, P. K., & El-Sayed, M. A. "Plasmonic coupling in noble metal nanostructures". Chemical Physics Letters, 487(4), 153-164 (2010). CrossRef Cataldi, U., Caputo, R., Kurylyak, Y., Klein, G., Chekini, M. Cesare Umeton, C., Bürgi, T. "Growing gold nanoparticles on a flexible substrate to enable simple mechanical control of their plasmonic coupling". J. Mater. Chem. C, 2, 7927-7933 (2014). CrossRef

Since 2002, yellowing symptoms associated with high levels of white-fly populations have been observed in plants of protected tomato crops in France. Symptomatic plants exhibited interveinal yellowing areas in older leaves, followed by generalized yellowing. Symptoms were not observed in young plants or fruits. Trialeurodes vaporariorum populations were generally abundant in spring, and Bemisia tabaci (established in France for approximately 10 years) became predominant in summer and fall. To check for the presence of Tomato chlorosis virus (ToCV) and Tomato infectious chlorosis virus (TICV), two whitefly-transmitted criniviruses known to induce yellowing symptoms, 696 samples were collected in the major tomato-growing areas; 573 samples from southern France and 123 samples from northern France. Total RNA was extracted from each sample and analyzed using reverse transcription-polymerase chain reaction (RT-PCR). Primers specific to ToCV (2) and TICV (1,3) were used to amplify either part of the heat-shock-like protein gene HSP70h (both viruses) or part of the diverged coat protein gene (CPd), (TICV only). A 439-bp DNA fragment was obtained with ToCV primers in 178 samples from southern France collected mainly from mid-spring to early fall from 2002 to 2004. Three RT-PCR products amplified from samples collected from diverse growing areas were sequenced and showed 99 to 100% sequence identity with published ToCV sequences from Spain (GenBank Accession Nos. AF215818, AF233435, and AF215817), Portugal (GenBank Accession No. AF234029), Sicily (GenBank Accession No. AY048854), and the United States (GenBank Accession No. AF024630). Considering the high frequency of ToCV-infected samples (41 positive samples of 112 samples collected in 2002, 71 of 295 collected in 2003, and 66 of 166 collected in 2004), this virus appears to be well established in southern France but remains absent in the northern regions. The presence of TICV was tested in 485 samples using the CPd-specific primers or the HSP70h-specific primers. The virus was detected in only two samples from Nice (southeastern France) in 2003 with both primer pairs. The CPd DNA fragment (700 bp) from one of these samples was sequenced, showing 98.9% sequence identity with a TICV Japanese isolate (AB085603). Results of these assays suggest that in contrast to ToCV, TICV is not yet broadly established in France. This difference could be associated with the specificity of the vectors, since ToCV is transmitted by B. tabaci and T. vaporariorum, while TICV is transmitted only by T. vaporariorum (4). References: (1) R. H. Li et al. Plant Dis. 82:84, 1998. (2) D. Louro et al. Eur. J. Plant Pathol. 1065:589, 2000. (3) A. M. Vaira et al. Phytoparasitica 30:290, 2002. (4) G. C. Wisler et al. Plant Dis. 82:271, 1998.

To improve online learning pedagogy within the field of paralegal education, this study investigated how paralegal students and paralegal instructors perceived the effectiveness of synchronous and asynchronous online paralegal courses. This study intended to inform paralegal instructors and course developers how to better design, deliver, and evaluate effective online course instruction in the field of paralegal studies.Survey results were analyzed using independent samples t-test and correlational analysis, and indicated that overall, paralegal students and paralegal instructors positively perceived synchronous and asynchronous online paralegal courses. Paralegal instructors reported statistically significant higher perceptions than paralegal students: (1) of instructional design and course content in synchronous online paralegal courses; and (2) of technical assistance, communication, and course content in asynchronous online paralegal courses. Instructors also reported higher perceptions of the effectiveness of universal design, online instructional design, and course content in synchronous online paralegal courses than in asynchronous online paralegal courses. Paralegal students reported higher perceptions of asynchronous online paralegal course effectiveness regarding universal design than paralegal instructors. No statistically significant differences existed between paralegal students’ perceptions of the effectiveness of synchronous and asynchronous online paralegal courses. A strong, negative relationship existed between paralegal students’ age and their perceptions of effective synchronous paralegal courses, which were statistically and practically significant. Lastly, this study provided practical applicability and opportunities for future research. Akyol, Z., & Garrison, D. R. (2008). The development of a community of inquiry over time in an online course: Understanding the progression and integration of social, cognitive and teaching presence. Journal of Asynchronous Learning Networks, 12, 3-22. Retrieved from https://files.eric.ed.gov/fulltext/EJ837483.pdf Akyol, Z., Garrison, D. R., & Ozden, M. Y. (2009). Online and blended communities of inquiry: Exploring the developmental and perceptional differences. The International Review of Research in Open and Distributed Learning, 10(6), 65-83. Retrieved from http://www.irrodl.org/index.php/irrodl/article/view/765/1436 Allen, I. E., & Seaman, J. (2014). Grade change: Tracking online education in the United States. Babson Park, MA: Babson Survey Research Group and Quahog Research Group, LLC. Retrieved from https://www.utc.edu/learn/pdfs/online/sloanc-report-2014.pdf Alreck, P. L., & Settle, R. B. (2004). The Survey Research Handbook (3rd ed.) New York, NY: McGraw-Hill Irwin. American Association for Paralegal Education (2013, Oct.). AAfPE core competencies for paralegal programs. Retrieved from https://cdn.ymaws.com/www.aafpe.org/resource/resmgr/Docs/AAfPECoreCompetencies.pdf American Bar Association, Standing Committee on Paralegals. (2017). https://www.americanbar.org/groups/paralegals.html American Bar Association, Standing Committee on Paralegals (2013, September). Guidelines for the approval of paralegal education programs. Retrieved from https://www.americanbar.org/content/dam/aba/administrative/paralegals/ls_prlgs_2013_paralegal_guidelines.authcheckdam.pdf Astani, M., Ready, K. J., & Duplaga, E. A. (2010). Online course experience matters: Investigating students’ perceptions of online learning. Issues in Information Systems, 11(2), 14-21. Retrieved from http://iacis.org/iis/2010/14-21_LV2010_1526.pdf Bailey, C. J., & Card, K. A. (2009). Effective pedagogical practices for online teaching: Perception of experienced instructors. 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El factor acompañamiento familiar y su incidencia en el desempeño académico de los estudiantes de undécimo grado es, en esencia, el motivo de esta investigación que, a través de una metodología cualitativa-cuantitativa y de la técnica de grupos focales, permitió contextualizar el problema e involucrar a los actores en la reflexión pedagógica, identificando con mayor claridad los roles para un buen desempeño en las Pruebas Saber. Así, se pudo encontrar que el acompañamiento se asocia con el cubrimiento de necesidades básicas, el aprendizaje de los oficios y el fomento de los valores. Fueron identificadas debilidades tales como: el conformismo, la falta de diálogo intrafamiliar y con el colegio, y la falta de confianza en el futuro de los hijos. Con estas apreciaciones se deduce que el acompañamiento familiar no es un factor determinante en los desempeños académicos, y que el éxito escolar depende del proceso permanente y riguroso durante todas las etapas del desarrollo del estudiante. En consecuencia, se propone una Ruta de Intervención Pedagógica para el Acompañamiento Familiar, en procura del mejoramiento de la calidad educativa en la institución. Referencias Chaves, L. (2001). Implicaciones educativas de la teoría sociocultural de Vigotsky. Revista Educación, 25(2), 59-65. Coleman, J. y Hendry, L. (2003). Psicología de la adolescencia. Madrid, España: Ediciones Morata. Creswell, J. (2009). Research Design. Qualitative, Quantitative, and Mixed Methods Approaches. United States of America: University of Nebraska-Lincoln. De Zubiría, J. (2006). Los modelos pedagógicos: hacia una pedagogía dialogante (2a. ed.). Bogotá, Colombia: Cooperativa Editorial Magisterio. Facultad de Posgrados y Relaciones Internacionales, Maestría en Pedagogía. (s.f.). Recuperado de http://www.umariana.edu.co/pedagogia/5-INVESTIGACION/ANEXO%2025.% 20Documento%20Linea%20investigaci%C3%B3n%20Grupo%20INDAGAR.pdf Garreta, J. (2015). La comunicación familia-escuela en educación infantil y primaria. Revista de la Asociación de Sociología de la Educación, RASE, 8(1), 71-85. Goleman, D. & Griese, F. (1997). EQ. Emotionale Intelligenz. Germany: Deutscher Taschenbuch Verlag Hernández, R., Fernández, C. y Baptista, P. (2003). Metodología de la investigación (5ª. ed.). México: McGraw-Hill Interamericana. Pereira, Z. (2011). Los diseños de método mixto en la investigación en educación. Revista Electrónica Educare, 15(1), 15-29. Pita, S. y Pértegas, S. (2002). Investigación cuantitativa y cualitativa. Recuperado de https://www.fisterra.com/mbe/investiga/cuanti_cuali/cuanti_cuali.aspRestrepo, B. (1996). Investigación en educación. Recuperado de http://iutep.tec.ve/uptp/images/Descargas/materialwr/libros/BernardoRestrepo-InvestigacionEnEducacion.PDF Rodríguez, W. (1999). El legado de Vygotski y de Piaget a la educación. Revista Latinoamericana de Psicología, 31(3), 477-489. Savater, F. (1997). El valor de educar. Barcelona, España: Editorial Ariel. Torío, S. (2004). Familia, Escuela y Sociedad. Aula Abierta, 83(2004), 35-52.

The aim of this paper was to identify which psycholinguistic variables are better predictors of performance for healthy participants in a picture naming task and in a picture categorization task. A correlation analysis and a Path analysis were carried out. The correlation analysis showed that naming accuracy and naming latency are significant and positively correlated with lexical frequency and conceptual familiarity variables, whereas they are negatively correlated with H index. Reaction times in the categorization task were negatively correlated with lexical frequency and conceptual familiarity variables and positively correlated with visual complexity variable. The Path analysis showed that subjective lexical frequency and H index are the better predictors for picture naming task. In picture categorization task, for reaction times, the better predictor variables were subjective lexical frequency, conceptual familiarity and visual complexity. These findings are discussed considering previous works on the field. References Akinina, Y., Malyutina, S., Ivanova, M., Iskra, E., Mannova, E., & Dragoy, O. (2015). Russian normative data for 375 action pictures and verbs. Behavior research methods, 47(3), 691-707. doi: 10.3758/s13428-014-0492-9 Alario, F. X., & Ferrand, L. (1999). A set of 400 pictures standardized for French: Norms for name agreement, image agreement, familiarity, visual complexity, image variability, and age of acquisition. Behavior Research Methods, Instruments, & Computers, 31(3), 531-552. Alario, F. X., Ferrand, L., Lagnaro, M., New, B., Frauenfelder, U. H., & Seguí, J. (2004). Pre­dictors of picture naming speed. Behavior Research Methods, Instruments and Computers, 36, 140-155. doi: 10.3758/BF03195559 Albanese, E., Capitani, E., Barbarotto, R., & Laiacona, M. (2000). Semantic category disso­ciations, familiarity and gender. Cortex, 36, 733-746. Almeida, J., Knobel, M., Finkbeiner, M., & Caramazza, A. (2007). 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Abstract Increased B cell-activating factor (BAFF) and aberrant B cell survival and activation are associated with chronic graft versus host disease (cGVHD) in patients. Whether excessive BAFF production has a pathologic role in the development of cGVHD after allogeneic hematopoietic stem cell transplantation (allo-HCT) remains unknown. Herein, we address this hypothesis by employing BAFF knockout (KO) and BAFF overexpressing (Tg) donor mice in the major MHC mismatched C57BL/6 (B6)-to-BALB/c cGVHD model (Wu et al J Immunol 2013;191:488), except we increased the T cell depleted bone marrow (TCDBM) dose to 1x107 per recipient to improve engraftment. BALB/c recipients receiving TCDBM plus 1x106 splenocytes (Sp) are the disease group, and those receiving TCDBM only are controls. After verifying cGVHD phenotypic manifestations (including longevity, weight loss, eye and lung findings), we examined whether cGVHD mice had the increased BAFF and B cell findings as occur in human cGVHD (Sarantopoulos et al, Blood 2009; 113: 3865). We observed that cGVHD mice had higher BAFF/B cell ratios compared to controls (Fig. 1A, n=10 each). We fully characterized the peripheral B cell compartment in these mice, and found that the relative composition of B cell subsets was significantly altered in diseased mice. CD93 cell surface expression has been used in mice to define B cells that emigrate from BM and circulate through secondary lymphoid organs. In cGVHD mice, we found a significant increase in the relative proportion of CD93+ B cells and a significant decrease in the proportion of CD93- B cells (Fig1B). Also, a significant increase in the frequency of cells positive for the germinal center and activation marker GL7 was found only within CD93- B cell subset of cGVHD mice (Fig 1C). When stimulated via BCR ex vivo, this GL7+ mature B cell subset had significantly increased Syk and BLNK activation, measured by phosphoflow (n=5, p=0.008). We next aimed to determine whether high BAFF alone or high BAFF and alloantigen together lead to altered B cell homeostasis and to the promotion of GL7+ BCR-activated B cells. C57BL/6 (B6) BAFF Tg TCDBM cells were used as donor to afford excessive and persistent BAFF levels after HCT in either syngeneic or BALB/c recipients. After B6 BAFF Tg TCDBM to BALB/c HCT, body weight decreased significantly. By contrast, B6 BAFF Tg TCDBM to B6 syngeneic HCT recipients remained healthy (Fig.1D, left panel,*p=0.004). Notably, the frequency of the CD93-GL7+ B cell subset was increased in BALB/c mice that received B6 BAFF Tg TCDBM only, compared to recipients of syngeneic BAFF Tg or WT TCDBM only (Fig.1D, right panel, p=0.008). Thus, both BAFF and alloantigen are required for B cell activation after HCT. Together, our data also suggest that GL7+ B cells identify aberrantly BCR-activated B cells in murine cGVHD, arising in the setting of BAFF-driven altered B cell homeostasis. While polymorphisms in either donor or recipient BAFF genes are associated with human GVHD (Clark et al Blood 2011; 118: 1140), the source of excess BAFF after allo-HCT remains unknown. We addressed whether pathologic BAFF was derived from donor or recipient hematopoietic cells using TCDBM from B6 BAFF KO mice vs WT as donor cells for HCT to BALB/c recipients. Consistent with the known requirement of recipient BAFF for recovery of the B cell compartment after syngeneic transplant (Gorelik et al JEM 2003; 198:937), recovery of a donor peripheral B cell pool was not significantly different between groups. Remarkably, plasma BAFF levels were also not different between BALB/c recipients of B6 BAFF KO TCDBM +Sp vs recipients of WT TCDBM +Sp, suggesting that radioresistant recipient cells produced BAFF in cGVHD. Chronic GVHD-associated weight loss was also not different between groups (Fig.1E, representative of 3 separate experiments). We found that BAFF production in the engrafted KO recipient BM was uniformly low. Thus, we have now determined that non-BM, radioresistant recipient cells are the principal source of soluble pathologic BAFF in murine cGVHD. Further characterization of BAFF-producing cells is underway in order to identify therapeutic targets. In summary, we have now demonstrated that recipient-derived BAFF has a mechanistic role in aberrant activation of B cells in cGVHD. Our findings will lead to the development of anti-BAFF and BCR targeting agents for patients. This work was supported the National Institutes of Health (NHLBI R01 HL 129061-01). Figure 1 Figure 1. Disclosures No relevant conflicts of interest to declare.

The aim in this study is to investigate the interface between semantics and pragmatics in relation to the use of the indexical demonstrative ‘haay’ ‘this-S.F.’ in Jordanian Arabic (JA). It is argued here that an analysis of meaning in relation to context-sensitivity inherent in the use of ‘haay’ can give evidence to the view that semantic and pragmatic processes can be distinguished from each other. I have found that the meaning of ‘haay’ consists of three distinct levels: linguistic, semantic, and pragmatic meaning. The denotational and conventional senses of ‘haay’ comprise its linguistic meaning, its semantic meaning is generated when any of the variables in the linguistic meaning is selected in relation to 'narrow context', the pragmatic meaning depends on relating the semantic meaning to an entity in the physical context of interaction. The results of this study support the view that the boundary between semantics and pragmatics can be distinctively demarcated. 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With the aim of understanding the insertion of higher education into a new context of organization of society and State, which is managed according to the New Public Management, this work presents a comparative historical study of the organization of French and Brazilian higher education. It is concluded that the French adherence to the New Public Management is based on the knowledge economy, while the Brazilian one is based on State size reduction along the lines of the Washington Consensus; in addition, higher education institutions in both countries are organized to participate in competitions: in France, the international competition promoted by rankings, and in Brazil, the market competition.ResumoCom o objetivo de compreender a inserção do ensino superior dentro de um novo contexto de organização da sociedade e do Estado, gerido pela Nova Gestão Pública, o trabalho apresenta um estudo histórico comparativo da organização do ensino superior brasileiro e o francês. Conclui-se que a adesão francesa à Nova Gestão Pública tem como norte a economia do conhecimento, e a brasileira, a redução do Estado nos moldes do Consenso de Washington; e que as instituições de ensino superior nos dois países são organizadas para participarem de concorrências: na França, a internacional promovida pelos ranqueamentos, no Brasil, a mercantil.Palavras-chave: Ensino superior brasileiro, Ensino superior francês, Nova gestão pública, Universidade.Keywords: Brazilian higher education, French higher education, New public management, University.ReferencesAEBISCHER, S. Réinventer l'école, réinventer l'administration. Une loi pédagogique et managériale au prisme de ses producteurs. Politix, n. 98, n.2 p. 57-83 2012/2.AERES. Repères historiques. Agence d’évaluation de la recherche et de l’enseignement supérieur. Disponível em: <www.aeres-evaluation.fr/Agence/Presentation/Reperes-historiques>. Acesso em: 17 nov. 2016.AMARAL, N. C. 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E-learning is aptly a practical response to continuous learning given the surge in the use of information technology, and economic disruptions impinging on the schools. The need to shift to e-learning has been exacerbated by the COVID-19 pandemic. In this regard, we sought to develop an organizational assessment instrument to internally ascertain the level of readiness of the school for sustainable e- learning in the new normal. This assessment instrument was primarily developed for the use of the Mendiola Consortium member schools in their pursuit to conduct elearning. We intended that as an internal self-assessment it can diminish the threat of failure and provide some assurance of the successful implementation of e-learning. We noted that many survey instruments had been made to assess organizational readiness as a construct for e-learning. However, it revealed that these instruments have varying limitations in validity and reliability to establish the domains of organizational readiness for e-learning. We anchored our study on the organizational readiness model developed by Schreurs and Al-Huneidi (2012) and Mercado (2002). From our review of related literature, we were able to generate seven basic dimensions of our model, namely: teacher, student, curriculum, technology, administrative support, financial support, and learning environment. We used a mixed method of qualitative and quantitative approach to come up with a validated instrument. We conducted a three-phase approach in developing the instrument. The final instrument yielded 45 items to be rated on a five-point Likert scale. For its content validity, the Item-Content Validity Index ranged from 0.91 to 0.96, while the Scale-Content Validity Index was 0.94. It has a Cronbach alpha of .975 for its reliability. ReferencesAlok , Kumar (2011). 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The establishment of most embryonic stem (ES) cell lines requires the destruction of embryos. Some ES cell lines in mice and humans are currently derived from a single blastomere, so that remaining blastomeres can still develop into fetuses. However, the procedures currently in use for establishing these lines are very complicated, and other ES cell lines from the same species are needed (Chung et al. 2006 Nature 439, 216–219; Klimanskaya et al. 2006 Nature 444, 481–485). The objective of this study was to devise a method simpler than those previously described for establishing ES cell lines from a single blastomere in the cynomolgus monkey. Controlled ovarian stimulation and oocyte recovery have been described previously by Torii et al. (2000 Primates 41, 39–47). Cumulus-free mature oocytes were fertilized by intracytoplasmic sperm injection (ICSI), and then cultured at 38�C in 5% CO2, 5% O2 for 2 days. The zona pellucida of 4- to 5-cell-stage embryos was disrupted using acidic Tyrode's solution, and individual blastomeres were separated from the denuded embryos using trypsin. These blastomeres were cultured on mitomycin-C-treated mouse embryonic fibroblasts and ES medium containing adrenocorticotropic hormone (ACTH) (Ogawa et al. 2004 Genes to Cells 9, 471–477). After the formation of initial outgrowths, half of the medium was changed every other day until the outgrowths reached approximately 100 cells. Passage of putative monkey ES cells was performed by mechanical dispersion of the colonies and transfer to fresh feeders every 3–4 days until there were enough cells for enzymatic dispersion. One stable ES cell line was obtained from two 4- or 5-cell-stage embryos using ES medium containing ACTH. The morphology of this ES cell colony was consistent with the monkey ES cell colony previous described by Suemori et al. (2001 Dev. Dynamics 222, 273–279). The ES cell line was passaged more than 17 times, and the morphology of the ES cell colony did not differ between the first and seventeenth passages. The ES cells showed normal karyotype and retained pluripotency markers for primate ES cells including octamer-binding protein 4 (Oct-4), stage-specific embryonic antigen (SSEA)-4, tumor-rejection antigen (TRA)-1-60, and TRA-1-81. We are presently confirming whether this ES cell line possesses potencies to differentiate in all three embryonic germ layers using both an in vitro assay and teratoma formation. Here we showed that cynomolgus monkey ES cells can be derived from a single blastomere, without co-culturing another ES cell line, as has been done in previous studies on mice and humans. This method allows the establishment of ES cell lines from a single blastomere, leaving the other blastomeres available for embryo transfer. Thus, the method described here is simpler than previously described methods and alleviates some ethical concerns.

This article is an inductive argumentation and an empirical-analytical paradigm that evaluates the actual relationship between Gross Domestic Product (GDP) per capita and the Carbon Dioxide (CO2) in country groups of the G8 considered as developed in a period of time from 1960 to 2011. It was developed an Augmented Dickey-Fuller unit root (ADF), a Granger Causality Test and a Johansen Cointegration test. The results evidence the non-stationary of constrains in both countries. It was obtained a VAR model with two variables with a number of lags of four - VAR2 (4) to which were tested for causality by demonstrating a unidirectionality of GDP per capita to CO2. Keywords: economic growth, economic development, income distribution, environmental economics. References [1]G. Brundtland, «Our Common Future,» de Report of the World Commission on Environment and Development , 1987. [2]R. Bermejo, Del desarrollo sostenible según Brundtland a la sostenibilidad como biomimesis, Bilbao: Hegoa, 2014. [3]R. B. and. P. C. Fander Falconí, «Flacso,» 16 03 2016. [Online]. Available: https://www.flacsoandes.edu.ec/agora/62767-la-discutible-curva-de-kuznets. [Last access: 15 01 2021]. [4]E. Urteaga, «Las teorías económicas del desarrollo sostenible,» Cuadernos de Economía, vol. 32, nº 89, pp. 113-162, 2009. [5]V. K. Smith, Scarcity and Growth Reconsidered, Baltimore: The Johns Hopkins Press, 1979. [6]J. y. A. Medina, «Ingreso y desigualdad: la Hipótesis de Kuznets en el caso boliviano,» Espacios, vol. 38, nº31, p. 23, 2017. [7]M. Ahluwalia, «Inequality, poverty and development, » Journal of Development Economics, nº 3, pp. 307-342, 1976. [8]A. and R. D. Alesina, «Distributive politics and economic growth,» Quarterly Journal of Economics, vol. 109, nº 2, pp. 465-490, 1994. [9]R. Barro, «Inequality and growth in a panel of countries, » Journal of Economic Growth, vol. 5, nº 1, pp. 5-32, 2000. [10]M. A. Galindo, «Distribución de la renta y crecimiento económico,» de Anuario jurídico y económico escurialense, 2002, pp. 473-502. [11]A. Álvarez, «Distribución de la renta y crecimiento económico, Información Comercial Española, ICE,» Revista de economía, nº 835, pp. 95-100, 2007. [12]J. C. Núñez, «Crecimiento económico y distribución del ingreso: una perspectiva del Paraguay,» Población y Desarrollo, nº 43, pp. 54-61, 2016. [13]S. Kuznets, «Economic Growth and Income Inequality, » American Economic Review, nº 45, pp. 1-28, 1955. [14]J. A. and. C. J. Araujo, «Relación entre la desigualdad de la renta y el crecimiento económico en Brasil: 1995-2012.,» Problemas del desarrollo, vol. 46, nº 180, pp.129-150, 2015. [15]F. V. A. and P. C. Correa, «La Curva Medioambiental de Kuznets: Evidencia Empírica para Colombia Grupo de Economía Ambiental (GEA),» Semestre Económico, vol. 8, nº 15, pp. 13-30, 2005. [16]W. Malenbaum, World Demand for Raw Materials in 1985 and 2000, McGraw-Hill: New York, 1978. [17]W. Beckerman, «Economists, scientists, and environmental catastrophe,» Oxford Economic Papers, vol. 24, nº 3, 1972. [18]G. y. K. A. Grossman, «Economic Growth and the Environment,» The Quarterly Journal of Economics, vol. 110, nº 2, pp. 353-377, 1995. [19]N. Stokey, «Are there Limits to Growth?,» International Economic Review, vol. 39, nº 1, 1998. [20]W. and. C. W. Jaeger, «A Theoretical Basis for the Environmental Inverted-U Curve and Implications for International Trade,» de Discussant: Clive Chapple, New York, 1998. [21]T. B. K. B. R. and. G. K. Cavlovic, «A Mets-Analysis of Environmental Kuznets Curve Studies,» Agricultural and Resource Economics, nº 29, pp. 32-42, 2000. [22]M. and. S. T. Heil, «Carbon emissions and economic development: future trajectories based on historical experience, » Environment and Development Economics, vol. 6, nº 1, pp. 63-83, 2001. [23]U. S. R. and E. B. Soytas, «Energy consumption, income, and carbon emissions in the United States,» Ecological Economics, vol. 62, nº 3, pp. 482-489, 2007.[24]C. W. J. Granger, «Investigating causal relations by econometrics models and cross spectral methods,» Econometrica, nº 37, pp. 424-438, 1969. [25]M. and U. R. Nasir, «Environmental Kuznets Curve for carbon emissions in Pakistan: An empirical investigation,» Energy Policy, vol. 39, nº 3, pp. 1857-1864,2011. [26]S. Johansen, «Statistical Analysis of Cointegration Vectors,» Journal of Economic Dynamics and Control, vol. 12, nº 2, pp. 231-254, 1988. [27]B. Goldman, «Meta-Analysis of Environmental Kuznets Curve Studies: Determining the Cause of the Curve’s Presence,» de Honors Projects, 2012. [28] M. B. and T. T. Fosten, «Dynamic misspecification in the environmental Kuznets curve: Evidence from CO2 and SO2 emissions in the United Kingdom,» Ecological Economics, vol. 76, pp. 25-33, 2012.

Измерены спектры поглощения пара монохлорида индия, находящегося в состояниях насыщенного и ненасыщенного пара относительно расплава InCl в присутствии расплава металлического индия. Спектры исследованы в интервале длин волн 200 – 400 nm и диапазоне температур 225 – 850 °C. Показано, что в этих условиях пар состоит из молекул InCl и в пределах чувствительности эксперимента не содержит других молекулярных форм хлоридов индия. В ходе нуль-манометрического эксперимента найдена температурная зависимость ln pInCl = = – A/T + b давления насыщенного пара в трехфазном равновесии LIn – LInCl – V, параметры которой составили: A = – 10255 ± 69 К, b = 10,95 ± 0.08 (давление – относительно стандартного 1 atm). Показано, что угловой коэффициент A хорошо согласуется с угловым коэффициентом температурной зависимости коэффициента поглощения ln Tk() = – A/T + B() при различных длинах волн. Это позволяет рассматривать высокотемпературную спектрофотомерию пара как альтернативу прямому манометрическому эксперименту. При сопоставлении манометрических и спектрофотометрических данных определены значения молярного коэффициента экстинкции InCl в ненасыщенном паре для максимумов полос поглощения. Найдено, что этот коэффициент слабо линейно зависит от температуры, убывая или возрастая на разных длинах волн. ИСТОЧНИК ФИНАНСИРОВАНИЯ Работа выполнена при финансовой поддержке РФФИ, проект 18-33-00900-мол-а. ЛИТЕРАТУРА Sen D., Heo N., Sef K. Phys. Chem. C, 2012, vol. 116, no. 27, pp. 14445–14453. https://doi.org/10.1021/jp303699u Kitsinelis S., Zissis G., Fokitis E. Physics D: Appl. Phys., 2009, vol. 42, p. 045209 (8 pp). https://doi.org/10.1088/0022-3727/42/4/045209 Hayashi D., Hilbig R., Körber A., et al. Phys. Letters, 2010, vol. 96, p. 061503. https://doi.org/10.1063/1.3318252 Binnewies M., Schmidt M., Schmidt P. Anorg. Allg. Chem., 2017, vol. 643, pp. 1295–1311. https://doi.org/10.1002/zaac.201700055 Zavrazhnov A. Y., Turchen D. N., Naumov A. V., Zlomanov V. P. Phase Equilibria., 2003, vol. 24, no. 4, pp. 330-339. https://doi.org/10.1361/105497103770330316 Fedorov P. I., Akchurin R. Kh. Indium. Moscow, Nauka Publ., 2000, 276 p. (in Russ.) Zavrazhnov A. Yu., Naumov A. V., Pervov V. S., Riazhskikh M. V. Thermochimica Acta, 2012, vol. 532, pp. 96–102. https://doi.org/10.1016/j.tca.2010.10.004 Zavrazhnov A. Yu., Naumov A. V., Sergeeva A. V., Sidei V. I. Inorganic Materials, 2007, vol. 43, no. 11, pp. 1167–1178. https://doi.org/10.1134/s0020168507110039 Zavrazhnov A. Yu, Kosyakov A. V, Sergeeva A. V., Berezin S. S. Condensed Matter and Interphases, vol. 17, no. 4, pp. 417 – 436. URL: https://journals.vsu.ru/kcmf/article/view/87/190 (in Russ.) Brebrick R. F. Phase Equilibria and Diffusion, 2005, vol. 26 no. 1, pp. 20 – 21. https://doi.org/10.1007/s11669-005-0054-z Kuniga Y., Hosaka M. Cryst. Growth, 1975, vol. 28, pp. 385–391. https://doi.org/10.1016/0022-0248(75)90077-9 Froslie H. M., Winans J. G. Rev., 1947, vol. 72, iss. 6, pp. 481–491. https://doi.org/10.1103/physrev.72.481 Jones W. E., McLean T. D. Molecular Spectroscopy, 1991, vol. 150, iss. 1, pp. 195-200. https://doi.org/10.1016/0022-2852(91)90202-l Vempati S. N., Jones W. E. Molecular Spectroscopy, vol. 132, iss. 2, pp. 458–466. https://doi.org/10.1016/0022-2852(88)90339-6 Kunia Y., Hosada S., Hosuka M. Denki Kagaku – Technical Paper, 1974, vol. 42, pp. 20–25. Robert C. Phys. Acta, 1936, vol. 9, pp. 405–436. Fedorov P. I., Mokhosoyev M. V. Gallium, Indium and Thallium Chemistry. Novosibirsk, Nauka Publ., 1977, 224 p. (in Russ.) Dritz M. E., Budberg P. ., Burkhanov G. S., et al. Properties of the Elements. Handbook, ed. by Dritz M. E. Moscow, Metallurgia Publ., 1985, 672 p. (in Russ.) Bronnikov A. D., Valilevskaya I., Niselson L. A. Izv. AN. SSSR. Metally, 1974, no. 4, pp. 54–57. (in Russ.) Zavrazhnov A. Yu. Doct. chem. sci. Voronezh, 2004, 340 p. Zavrazhnov A. Yu. Russian Journal of Inorganic Chemistry, 2003, vol. 48, no. 10, pp. 1577–1590. (in Russ.) Brebrick R. F., Su C.-H. Phase Equilibria, 2002, vol. 23, 2002, pp. 397–408. https://doi.org/10.1361/105497102770331343 Suvorov A. V. Thermodynamicheskaya chimia paroobraznogo sostoyania [Thermodynamic Chemistry Vapor State]. Leningrad, Chimia Publ., 1970, 208 p. (in Russ.)

RESUMENLa pretensión de este artículo es ofrecer una serie de reflexiones y valoraciones metodológicas sobre la historia medieval de la Iglesia y la religiosidad partiendo de algunos aspectos destacados de la producción historiográfica reciente y esbozar ciertas propuestas en la misma clave metodológica. Este ensayo reflexiona sobre temas, enfoques y perspectivas, sobre los niveles de estudio de lo religioso y sobre la integración de la historia de la Iglesia y la historia social, y aboga por una historiasocial de la Iglesia.PALABRAS CLAVE: Historia Medieval, Historia de la Iglesia y la vida religiosa en la Edad Media, Metodología histórica, Liturgia y sociedad, Tendencias historiográficas.ABSTRACTThe aim of this article is to offer a series of reflections and methodological evaluations on the medieval history of the Church and religiosity based on some outstanding aspects of recent historiographical production, and to outline certain proposals in the same methodological vein. This essay reflects on themes, approaches and perspectives, on the levels of study of the religious and on the integration of the history of the Church and social history, and advocates a social history of the Church.KEY WORDS: Medieval History, History of the Church and religious life in the Middle Ages, historical methodology, liturgy and society, historiographical trends. BIBLIOGRAFÍAAbad Ibáñez, J. A., La celebración del misterio cristiano, Pamplona, Eunsa, 1996.Andrés-Gallego, J., “Historia religiosa en España”, Anuario de historia de la Iglesia, 4 (1995), pp. 259-270.Araus Ballesteros, L. y Prieto Sayagüés, J. A. (coords.), Las tres religiones en la Baja Edad Media peninsular. Espacios, percepciones y manifestaciones, Madrid, La Ergástula, 2018.Arranz Guzmán, A., “Amores desordenados y otros pecadillos del clero”, en Carrasco Manchado, A. I. y Rábade Obradó, M. del P. (coords.), Pecar en la Edad Media, Madrid, Sílex, 2008, pp. 227-262.Asensio Palacios, J. C., “Neuma, espacio y liturgia. La ordenación sonora en Compostela según el Codex Calixtinus”, Medievalia, 17 (2014), pp. 131-152.Asociación de historia religiosa contemporánea, http://www.aehrc.es/ (consulta: 2-1-2019).Associaçâo Nacional de História, Brasil, http://www.snh2013.anpuh.org/ (consulta: 28-12-2018).Aurell, J. y Pavón Benito, J. (eds.), Ante la muerte: actitudes, espacios y formas en la España medieval, Pamplona, Universidad de Navarra, 2002.Bartolomé Herrero, B., Iglesia y vida religiosa en la Segovia medieval (1072-1406), Tesis Doctoral, Madrid, Universidad Complutense, 2000.Bartolomé Herrero, B., “Los obispos de Segovia en la Edad Media. Siglos XII, XIII y XIV”, Anthologica annua, 63 (2016), pp. 11-561.Bazán Díaz, I., Los herejes de Durango y la búsqueda de la Edad del Espíritu Santo en el siglo XV, Durango, Museo de historia y arte de Durango, 2007.Beceiro Pita. I. 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The aim of this study was to characterise conditions and factors affecting fine sand clogging by septic tank effluent on the basis of physical modelling. The physical model consisted of 12 sand columns dosed with sewage from one household (5 persons), preliminary treated in a septic tank. Hydraulic loadings of the sand filters were equal to 82 mm/d. The mean discharge from sand columns, measured as the effluent volume collected during 10 minutes, decreased significantly over the experiment period from 34 cm3/min in August 2000 to 20 cm3/min in August 2001 at the same temperature of about 20°C. First the columns clogged almost completely after 480 days in December 2001, however six columns had remained unclogged till the end of the experiment (March 2002). The temperature had a significant impact on hydraulic conductivity. A vertical distribution of accumulated mass and biomass was investigated in partly clogged sand. Microscopic survey of the clogging layer showed a presence of live micro-organisms, residuals of dead micro-organisms, particularly pieces of small animal armour and many fibres. These particles accelerated the accumulation of solids in the upper clogging layer. The study indicated that temperature impact on the filter hydraulic conductivity was more significant for biological activity, than for sewage viscosity.

RESUMENLa Tierra de Lemos es una comarca gallega del sur de la provincia de Lugo, heredera en lo sustantivo de un territorium y una terra medievales, a su vez continuadoras del solar protohistórico de los Lemaui. La continuidad en sus realidades permite el estudio de la evolución espiritual de sus células básicas de poblamiento: las parroquias. Las advocaciones, invariables en muchos casos, modificadas en otros, son así sillares en el edificio histórico del territorio. En este artículo estudiamos la evolución del listado de devociones titulares de las feligresías de Lemos a través de la documentación medieval, y la información que la estabilidad y los cambios nos pueden ofrecer. Palabras clave: parroquia, advocacionesTopónimos: Lemos, Lugo, GaliciaPeríodo: siglo vi, siglo xv ABSTRACTThe county of Lemos is a district located in the south of the province of Lugo. Its origins go back to protohistory when it was occupied by the Lemavi tribe, and it subsequently became a territorium and a terra in the Middle Ages. The county’s history is marked by continuity, which allows us to study the spiritual evolution of its parishes. The saints chosen by the community as its protectors are historic testimonials of the time. In this paper, we study the list of church parish devotions in Lemos through medieval documentation. Our objective is to improve our knowledge about this medieval county by studying both the stability and changes in its parish saints. Keywords: parish, advocationPlace names: Lemos, Lugo, GaliciaPeriod: 6th century, 15th century REFERENCIASAndrade Cernadas, J. 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Brucella spp. and Leptospira spp. antibodies were surveyed in 35 southern elephant seals (SESs) Mirounga leonina at Elephant Island (South Shetland Islands), western Antarctic peninsula, in the Austral summer of 2003 and 2004. The rose Bengal test and a commercial competitive ELISA (c-ELISA) were used to detect Brucella spp. exposure, and the microscopic agglutination test (MAT) with 22 live serovars was used to determine anti-Leptospira spp. antibodies. We found evidence of Brucella spp. exposure in 3 of 35 (8.6%) SESs tested via the c-ELISA displaying high percentage inhibition (PI), similar to other studies in pinnipeds in which Brucella spp. antibodies have been determined. Two of the 3 positives were pups (PI = 70.4 and 86.6%), while the third was an adult female (PI = 48.8%). The 3 c-ELISA positive SESs were additionally tested via the serum agglutination test but were found to be negative. All individuals were negative for antibodies against 22 Leptospira spp. serovars by MAT. These results contribute to the knowledge and monitoring of zoonotic pathogens with epizootic potential in Southern Ocean pinnipeds. Given the potential impact that pathogens may have on the abundance of wild (sometimes threatened and endangered) populations, constant monitoring and surveillance are required to prevent pathogen spread, particularly under forecast climate change scenarios.

Abstract. High latitude wetlands play an important role for the surface-atmosphere exchange of carbon dioxide (CO2) and methane (CH4), but fluxes of biogenic volatile organic compounds (BVOC) in these ecosystems have to date not been extensively studied. This is despite BVOC representing a measurable proportion of the total gaseous C fluxes at northern locations and in the face of the high temperature sensitivity of these systems that requires a much improved process understanding to interpret and project possible changes in response to climate warming. We measured emission of isoprene and photosynthetic gas exchange over two growing seasons (2005–2006) in a subarctic wetland in northern Sweden with the objective to identify the physiological and environmental controls of these fluxes on the leaf scale. The sedge species Eriophorum angustifolium and Carex rostrata were both emitters of isoprene, and springtime emissions were first detected after an accumulated diurnal mean temperature above 0°C of about 100 degree days. Maximum measured growing season standardized (basal) emission rates (20°C, 1000 μmol m−2 s−1) were 1075 (2005) and 1118 (2006) μg C m−2 (leaf area) h−1 in E. angustifolium, and 489 (2005) and 396 (2006) μg C m−2 h−1 in C. rostrata. Over the growing season, basal isoprene emission varied in response to the temperature history of the last 48 h. Seasonal basal isoprene emission rates decreased also with leaf nitrogen (N), which may be explained by the typical growth and resource allocation pattern of clonal sedges as the leaves age. The observations were used to model emissions over the growing season, accounting for effects of temperature history, links to leaf assimilation rate and the light and temperature dependencies of the cold-adapted sedges.

Abstract. High latitude wetlands play an important role for the surface-atmosphere exchange of carbon dioxide (CO2) and methane (CH4), but fluxes of biogenic volatile organic compounds (BVOC) in these ecosystems have to date not been extensively studied. This is despite BVOC representing a measurable proportion of the total gaseous C fluxes at northern locations and in the face of the high temperature sensitivity of these systems that requires a much improved process understanding to interpret and project possible changes in response to climate warming. We measured emission of isoprene and photosynthetic gas exchange over two growing seasons (2005–2006) in a subarctic wetland in northern Sweden with the objective to identify the physiological and environmental controls of these fluxes on the leaf scale. The sedge species Eriophorum angustifolium and Carex rostrata were both emitters of isoprene. Springtime emissions were first detected after an accumulated diurnal mean temperature above 0°C of about 100 degree days. Maximum measured growing season standardized (basal) emission rates (20°C, 1000 μmol m−2 s−1) were 1075 (2005) and 1118 (2006) μg C m−2 (leaf area) h−1 in E. angustifolium, and 489 (2005) and 396 (2006) μg C m−2 h−1 in C. rostrata. Over the growing season, basal isoprene emission varied in response to the temperature history of the last 48 h. Seasonal basal isoprene emission rates decreased with leaf nitrogen (N), which may be explained by the typical growth and resource allocation pattern of clonal sedges as the leaves age. The observations were used to model emissions over the growing season, accounting for effects of temperature history, links to leaf assimilation rate and the light and temperature dependencies of the cold-adapted sedges.

One hundred sixty-seven children with traumatic brain injury (TBI), selected from an 8-year series of consecutive referrals to a Midwestern rehabilitation hospital, completed the California Verbal Learning Test–Children's Version (CVLT–C) and the Wechsler Intelligence Scale for Children–Third Edition (WISC–III) within 1 year after injury. A large proactive interference (PI) effect, defined as performance on the second list that was at least 1.5 standard deviations below that on the 1st one, was statistically significantly more common in this clinical sample (21%) than in the CVLT–C standardization sample (11%). Other performance discrepancies, including retroactive interference, rapid forgetting, and retrieval problems, occurred at approximately the same rate in the clinical and standardization samples. Children with anterior cerebral lesions were about 3 times less likely to have a large PI effect than children without such lesions, but the former group performed worse on the first CVLT–C list. The impact of pediatric TBI on a wide range of CVLT–C quantitative variables was mediated by speed of information processing, as assessed by the WISC–III Processing Speed factor index. It is concluded that failure to release from PI is somewhat common, although certainly not universal, in children with TBI. Unlike with adults, anterior cerebral lesions are not associated selectively with an increased risk for PI after pediatric TBI but rather with a reduced efficiency of allocation of cognitive resources. Deficits in speed of information processing appear to be primarily responsible for the learning deficits on the CVLT–C after pediatric TBI. (JINS, 2004, 10, 482–488.)

In the spring of 2006, chief and senior residents were surveyed to determine how they prepared for their senior administrative/leadership role, what topics should be included in a leadership workshop and how this workshop should be delivered. Overall, 32.3% had no prior contact with the previous chief resident. Among those prepared, 46% consulted previous chiefs/seniors and/or program directors. Eighty-five percent agreed that a leadership workshop would be beneficial for future chiefs. Using the results from this environmental scan, a planning committee was formed to design the First Annual Chief Resident Leadership Workshop, held in August 2006, to identify and develop leadership skills while providing them with the resources to ease their transition into this senior administrative role. Seven sessions were offered: Your Role as Chief Resident, Mentorship, overview of the residents’ work/education contract, Personality Inventory (i.e. Myers-Briggs), Anti-Racism and Harassment, Resident Wellness and Public Speaking. A keynote address on leadership in academic medicine was given by a well-known Canadian clinician leader. To reinforce the experience, a resource binder and handbook was distributed to all participants. Quality and content of each session was evaluated using on a 5-point Likert scale. Mean scores were calculated. Mentorship scored the highest in terms of quality (4.46) and content (4.47), followed by Leadership in Academic Medicine (4.43 and 4.62, respectively). Over 90 % agreed that a leadership program is necessary. Parallel to our earlier findings, many chief residents use multiple sources to prepare for their role, primarily the pairing of contact with the previous chief resident and the Program Director. The results indicate that a formal, centralized leadership workshop/seminar is valued and should highlight the necessary skills set and provide key resources. Susman J, Gilbert C. Family practice residency directors’ perceptions of the position of chief resident. Academic Medicine 1992; 67(3):212-213. Awad JJ, Levenson SM, Osman CH, James S. The impact of a novel resident leadership training curriculum. The American Journal of Surgery 2004; 188:481-484. Kasuya RT, Nip IL. A retreat on leadership skills for residents. Academic Medicine 2001; 76(5):554.

BackgroundOver the last 20 years aggressive therapy for inflammatory joint diseases (IJD) has become standard of care following the acceptance of Methotrexate as anchor drug and extensive of use biologic therapy since 2003. Immunosuppression increases the risk for common and uncommon infections (1).ObjectivesTo compare the temporal rates and associated mortality of hospitalisation with opportunistic infections (OI) (Table 1) for IJD patients in Western Australia between 1985 and 2015.MethodsAll patients hospitalized in Western Australia in the period 1980-2015 with ≥ 2 diagnostic codes for rheumatoid arthritis (RA, n=8490), psoriatic arthritis (PsA, n=601), axial spondylarthritis (AS, n=1419). Overall incidence rates (IR) with microbiologically confirmed OI (Mycobacterial, Fungal and viral infections)(Table 1) during 306.514 person years were expressed per 1000 person years and compared across IJD by incidence rate ratios (IRR) with 95% CI. IR trend rates across 5-year periods for each IJD were analyzed by least square regression (R2). Mortality rate ratio (MRR) was number of deaths per 1000 observation years in patients with OI compared to patients in same disease category hospitalized without OI.Table 1.Diagnostic codes applied to define conditions and opportunistic infections in hospital discharge database.ICD9CMICD10AMRA714.0-714.9M05.0-M06.9AS720.0M45, M08.10-M08.19PsA696.0M07.0-M07.3, L40.5 Tuberculosis010.x-018.xA15–A19 Non-tuberculous mycobacteria031.xA30-A31 Cryptococcosis117.5B45 Aspergillosis117.3B44 Histoplasmosis115B39 All mycosis114.0 - 118.9B35.0 - B49.9 Pneumocystosis136.3B59 Cytomegaloviral disease078.5B25 Influenza487.x, 488.xJ09, J10 Herpes zoster053.xB02 Varicella052.xB01ResultsThe IR for all OI in RA patients (5.19, CI 4.8-5.6) was significantly higher than for PsA (IRR 0.56, CI 0.41-0.76 and AS (IRR 0.64, CI 0.53-0.79) with lower IRR observed especially for tuberculosis and H Zoster in PsA (0,49 and 0,47) and AS patients (0,43 and 0,49). H Zoster, TBC and other mycobacteria were the most frequent cause of OI with cryptococcal and pneumocystis only seen in RA. The IR for TBC decreased over time in RA (R2 0.51, p=0.08), and AS (R2 0.47, p=0.09) while the IR for H. zoster decreased in RA only (R2 0.46, p=0.09) (Figure 1). In-hospital mortality rate in patients with OI was 4.9 % for RA, 2.6 % for PsA and 2.2% for AS, but MRR for RA (1.15; 0.71-1.97), PsA (1.64; 0.82-3.57) and AS patients (1.35; 0.68-2.89) was not significantly increased.Figure 1.Incidence rate per 1000 personyears over time for hospitalisation with opportunistic infections in RA patients.ConclusionThe IR for hospitalization with OI is twice as high for RA patients compared to AS and PsA patients. Admission rates for most OI including have decreased in RA patients over the two decades where more intensive treatment became standard of care. This suggests efficacy of preventative measures. Hospital admission with OI associated with a moderate risk of death, but did not incur a higher risk of death than admission for other medical complications in IJD patientsReferences[1]Wang D, Yeo AL, Dendle C, Morton S, Morand E, Leech M. Severe infections remain common in a real-world rheumatoid arthritis cohort: A simple clinical model to predict infection risk. Eur J Rheumatol 2021; 8(3): 133-8.AcknowledgementsSupported by an unrestricted grant from the Arthritis Foundation of Western Australia.Disclosure of InterestsNone declared

SUMMARYCryptosporidiuminfects millions of people worldwide causing acute gastroenteritis, but despite its remarkable epidemiological and economic impact, information on the epidemiological trends of human cryptosporidiosis is still scarce in most countries. Here we investigate a panel of 486 cases collected in Galicia (NW Iberian Peninsula) between 2000 and 2008, which sheds new light on the epidemiology in this region of the South Atlantic European façade. Incidence rates in Galicia are one order of magnitude higher than those reported in other regions of Spain, suggesting that this parasite remains largely underdiagnosed in this country, and are also larger than those typical of other European countries with available data. Two species dominate our dataset,Cryptosporidium hominis(65%) andC. parvum(34%). The sex ratio of patients infected by either species was 0·5, butC. hominiswas significantly more common in younger males.C. parvuminfections were more acute and required more specialized medical attention, which suggests a differential adaptation of each species to human hosts. The parasites display strong seasonal and geographical variation.C. parvumincidence peaked during summer and was mainly detected in rural areas whileC. hominisinfections were more frequent in autumn and exhibited a more even geographical distribution. Such differences probably reflect their distinct sources of infection – C. parvumis mainly zoonotic andC. hominisanthroponotic – and the effects of climatic variables, like temperature and rainfall.

Выявлен набор физических и химических характеристик реактора диэлектрического барьерного разряда и исследовано их влияние на степень удаления муравьиной кислоты из воздуха. Степень превращения муравьиной кислоты увеличивается при повышении удельной мощности разряда и уменьшается при увеличении скорости расхода воздуха и начальной концентрации поллютанта (степень превращения в начале процесса очистки была выше 90%). Оценены типовые показатели надёжности для реактора с диэлектрическим барьерным разрядом, их значения указывают на то, что устройства с такими реакторами целесообразно применять при очистке воздуха от низких концентраций муравьиной кислоты. Выявлено наличие процессов окисления электрода из Al при очистке воздуха от муравьиной кислоты. Список литературы Артёмов А.В. Расчётные методы определения загрязняющих веществ в атмосфере от предприятий по производству и переработке полимерных материалов. Екатеринбург: УГЛТУ, 2013. 35 с. Бубнов А.Г., Гриневич В.И., Костров В.В. Плазменная полимеризация паров органических веществ в барьерном разряде // Химия высоких энергий. 1991. Т. 25, №4. С. 365‒369. ГОСТ Р 27.013-2019 (МЭК 62308:2006) Надёжность в технике. Методы оценки показателей безотказности. Гущин А.А., Гриневич В.И., Козлов А.А., Извекова Т.В., Квиткова Е.Ю., Рыбкин В.В. Кинетические закономерности деструкции 1,4-дихлорбензола в диэлектрическом барьерном разряде атмосферного давления в кислороде // Химия высоких энергий. 2020. Т. 54, №1. C. 73–77. DOI: 10.31857/S0023119320010064. Драгинский В.Л., Алексеева Л.П., Самойлович В.Г. Озонирование в процессах очистки воды. М.: ДеЛи принт., 2007. 359 c. Зажигалов С.В., Микенин П.Е., Лопатин С.А., Баранов Д.В., Писарев Д.А., Чумакова Н.А., Загоруйко А.Н. Усовершенствованный адсорбционно-каталитический процесс для очистки отходящих газов от примесей летучих органических соединений // Катализ в промышленности. 2016. Т. 8, №3. С. 231–241. DOI: 10.18412/1816-0387-2016-3-38-48. ИТС 22-2016. Очистка выбросов вредных (загрязняющих) веществ в атмосферный воздух при производстве продукции (товаров), а также при произведении работ и оказании услуг на крупных мероприятиях. ИТС 47-2017. Системы обработки (обращения) со сточными водами и отходящими газами в химической промышленности. Кайряк С.В., Гриневич В.И., Костров В.В. Окисление бензола в плазме барьерного разряда // Известия высших учебных заведений. Сер.: Химия и химическая технология. 2000. Т. 43, №6. С. 68–72. Лунин В.В., Попович С.Н., Ткаченко С.Н. Физическая химия озона. М: Изд-во МГУ, 1998. 480 c. Основы аналитической химии / Под ред. Ю. А. Золотова. М.: Высшая школа, 2004. Т. 2. 503 с. Острейковский В.А. Теория надежности. М.: Высшая школа, 2003. 463 с. Распоряжение Правительства Российской Федерации от 8.07.2015 г. №1316-p «Об утверждении перечня загрязняющих веществ, в отношении которых применяются меры государственного регулирования в области охраны окружающей среды». Самойлович В.Г., Гибалов В.И., Козлов К.В. Физическая химия барьерного разряда. М.: Изд-во МГУ, 1989. 176 c. Тодт Ф. Коррозия и защита от коррозии. Коррозия металлов и сплавов. Методы защиты от коррозии. М.; Л.: Химия, Ленингр. отд., 1966. 847 с. Karatum O.A., Deshusses M.A. Сomparative study of dilute VOCs treatment in a non-thermal plasma reactor // Chemical engineering journal. 2016. V. 294. P. 308–315. DOI: 1016/j.cej.2016.03.002.

China Low Activation Martensitic steel (CLAM), which is one of the RAFMs (Reduced Activation Ferritic/Martensitic steels) and under development in ASIPP, is considered as the primary candidate structural material and LiPb eutectic as both tritium breeder and coolant of the blankets in FDS series fusion reactors. The corrosion behavior of CLAM steel exposed to the liquid breeder LiPb is of significance. Corrosion tests of CLAM in flowing LiPb at 480°C were performed up to about 2000 hrs to analyze the corrosion mechanism of CLAM exposed to liquid LiPb. The specimens were observed and analyzed by Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Spectroscopy (EDX) after 500hrs, 1000hrs and 2000hrs corrosion experiment respectively. The corrosion is of non-uniform and the weight loss was about 0.23 mg/cm2 after 2000 hrs’ exposure, which is smaller for CLAM compared to those of other RAFMs.

We present the temperature dependent elastic and ultrasonic properties of sodium borohydride. The second and third order elastic constants of NaBH4 have been computed in the temperature range 0-300K using Coulomb and Born-Mayer potential. The sodium borohydride crystallizes into NaCl-type structure. The computed values of second order elastic constants have been applied to evaluate the temperature dependent mechanical properties such as bulk modulus, shear modulus, tetragonal modulus, Poisson’s ratio and Zener anisotropy factor and ultrasonic velocity to predict futuristic information about sodium borohydride. The fracture to toughness ratio (bulk modulus/shear modulus) in sodium borohydride varied from 1.91 to 1.62, which shows its behavioral change from ductile to brittle on increasing the temperature. Then, ultrasonic Grüneisen parameters have been computed with the use of elastic constants in the temperature regime 100-300K. The obtained results have been discussed in correlation with available experimental and theoretical results. [1] A. Amudhavalli, M. Manikandan, A. Jemmy Cinthia, R. Rajeswarapalanichamy and K. Iyakutti, Z. Naturforsch. A 72 (2017) 321. [2] D.Singh, P.K.Yadawa and S.K.Sahu, Cryogenics 50 (2010) 476. [3] V. Bhalla, D.Singh and S.K.Jain, Int. J. Comput. Mat. Sc. Eng. 5 (2016) 1650012. [4] S. Kaushik, D. Singh and G. Mishra, Asian J. Chem. 24 (2012) 5655. [5] D. Chernyshov, A. Bosak, V. Dmitriev, Y. Filmchuk and H. Hagemann, Phys. Rev. B 78 (2008)172104. [6] H. Hagemann, S. Gomes, G. Renaudin and K. Yvon, J. Alloys Compd. 363 (2004) 126. [7] Y. Filinchuk, D. Chernyshov and V. Dmitriev, Z. Kristallogr. 223 (2008) 649. [8] Z.Xiao Dong, J.Z. Yi, Z. Bo, H. Z. Feng and H.Y. Qing, Chin. Phys. Lett. 28(2011)076201. [9] T. Ghellab, Z. Charifi, H. Baaziz, Ş. Uğur, G. Uğur and F. Soyalp, Phys. Scr. 91 (2016) 045804. [10] S. Bae, S. Gim, H. Kim and K. Hanna, Appl. Catal. B: Environm. 182 (2016) 541. [11] G. Renaudin, S. Gomes, H. Hagemann, L. Keller and K. Yvon, J Alloys Compd. 375 (2004) 98. [12] P. Vajeeston, P. Ravindran, A. Kjekshus and H. Fjellvåg, J Alloys Compd. 387 (2005) 97. [13] S. Orimo, Y. Nakamori, J.R. Eliseo, A. Zuttel and C. M. Jensen, Chem. Rev. 107 (2007) 4111. [14] A. Istek and E. Gonteki, J. Environ. Bio.7 (2009) 951. [15] R. S. Kumar and A.L. Cornelinus, Appl. Phys. Lett. 87 (2005) 261916. [16] E. Kim, R. Kumar, P. F. Weck, A. L. Cornelius, M. Nicol, S. C. Vogel, J. Zhang, M. Hartl, A.C. Stowe, L. Daemen and Y. Zhao, J. Phys. Chem. Lett. B 111 (2007) 13873. [17] K. Brugger, Phys. Rev. 133 (1964) A1611. [18] P.B. Ghate, Phy. Rev. 139 (1965) A1666 [19] S. Mori, Y. Hiki, J. Phys. Soc. Jpn. 45 (1975) 1449. [20] V. Bhalla, R. Kumar, C. Tripathy and D. Singh, Int. J. Mod. Phys. B 27 (2013) 1350116. [21] D. Singh, S. Kaushik, S. Tripathi, V. Bhalla and A. K. Gupta, Arab. J. Sci. Eng. 39 (2014) 485. [22] K. Brugger, Phys. Rev.137 (1965) 1826. [23] W. P. Mason, Physical Acoustics, vol. IIIB, Academic Press, New York, 1965. [24] M.P. Tosi, Solid State Physics, vol. 12, Academic Press, New York, 1965. [25] Y. Nakamori and S. Orimo, J. Alloy Compd.370(2004)271. [26] D. Singh, D.K. Pandey and P.K. Yadawa, Cent. Eur. J. Phys. 7 (2009) 198. [27] V. Bhalla, D. Singh, G. Mishra and M. Wan, J. Pure Appl. Ultrason. 38 (2016)23. [28] D. Singh, S. Kaushik, S.K. Pandey, G. Mishra and V. Bhalla, VNU J. Sc.: Math. Phys. 32(2016)43. [29] J.P.Watt and L. Peselnick, J.Appl. Phys. 51 (1980) 1525. [30] S.F.Pugh, Philos.Mag. 45 (1954) 823. [31] V. Bhalla, D. Singh and S.K. Jain, Int. J. Thermophys. 37(2016)33. [32] V. Bhalla, D. Singh, S.K. Jain and R. Kumar, Pramana- J. Phys. 86 (2016)135.

Arsenic and Protein Expression: It might help to know the mechanism of As toxicity is described Introduction One of the largest public health problems at present is the drinking of water containing levels of Inorg-As that are known to be carcinogenic. The chronic ingestion of Inorg-As can results in skin cancer, urinary bladder cancer, lungs cancer, kidneys cancer, liver cancer, and cancer of other human organs 1-6. The molecular mechanisms of the carcinogenicity and toxicity of inorganic arsenic are not well understood 7–9. Many mechanisms of arsenic toxicity and carcinogenicity have been suggested 1, 7, 10 including chromosome abnormalities 11, oxidative stress 12, 13, altered growth factors 14, cell proliferation 15, altered DNA repair 16, altered DNA methylation patterns 17, inhibition of several key enzymes 18, gene amplification 19 etc. Some of these mechanisms result in alterations in protein expression. Proteomics is a powerful tool developed to enhance the study of complex biological system 20. This technique has been extensively employed to investigate the proteome response of cells to drugs and other diseases 21, 22. A proteome analysis of the Na-As (III) response in cultured lung cells found in vitro oxidative stress-induced apoptosis 23. In one of the study, hamsters were exposed to sodium arsenite (173 mg As/L) in drinking water for 6 days and several protein spots were over expressed and several were under expressed in the livers and urinary bladders of hamsters (Fig.) 24, 25. Hamsters were exposed to sodium arsenite (173 mg As/L) in drinking water for 6 days. The control hamsters were given tap water. The spot pairs of (A) equally expressed, (B) overexpressed, and (C) under expressed proteins in the liver tissues were shown. The amount of the protein is proportional to the volume of the protein peak. Transgelin was down-regulated, and GST-pi was up-regulated in the urinary bladder tissues of hamsters. In the liver tissues ornithine aminotransferase (OAT) was up-regulated, and senescence marker protein 30 (SMP 30), and fatty acid binding protein (FABP) were down-regulated. Down-regulation of transgelin has been noted in the urinary bladders of rats having bladder outlet obstruction 26. Ras-dependent and Ras-independent mechanisms can cause the down regulation of transgelin in human breast and colon carcinoma cell lines and patient-derived tumor samples 27. The loss of transgelin expression has been found in prostate cancer cells 28 and in human colonic neoplasms 29. It has been suggested that the loss of transgelin expression may be an important early event in tumor progression and a diagnostic marker for cancer development 26-29. Figure. Three-dimentional simulation of over-and under expressed protein spots in the livers of hamsters using Decyder software. Over-expression of GST-pi has been found in colon cancer tissues 30. Strong expression of GST-pi also has been found in gastric cancer 31, malignant melanoma 32, lung cancer 33, breast cancer 34 and a range of other human tumors 35. GST-pi has been up-regulated in transitional cell carcinoma of human urinary bladder 36. OAT has a role in regulating mitotic cell division and it is required for proper spindle assembly in human cancer cell 37. Ornithine amino transferase knockdown in human cervical carcinoma and osteosarcoma cells by RNA interference blocks cell division and causes cell death 37. It has been suggested that ornithine amino transferase has a role in regulating mitotic cell division and it is required for proper spindle assembly in human cancer cells 37. SMP 30 expressed mostly in the liver. By stimulating membrane calcium-pump activity it protects cells against various injuries 38. 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