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Статті в журналах з теми "2 cell-Embryo"
Evsikov, A. V., W. N. de Vries, A. E. Peaston, E. E. Radford, K. S. Fancher, F. H. Chen, J. A. Blake, et al. "Systems biology of the 2-cell mouse embryo." Cytogenetic and Genome Research 105, no. 2-4 (2004): 240–50. http://dx.doi.org/10.1159/000078195.
Повний текст джерелаFUNAHASHI, Hiroaki, and Koji NIWA. "Electric fusion of 2-cell rat embryo balastomeres." Japanese journal of animal reproduction 36, no. 2 (1990): 114–19. http://dx.doi.org/10.1262/jrd1977.36.114.
Повний текст джерелаZhang, M., L. Sui, Y. Li, Z. Chen, Y. Zhang, T. Liu, J. Xu, X. Zhang, and Y. Zhang. "96 EFFECT OF TWO DIFFERENT EMBRYO TRANSPORTERS ON DEVELOPMENT OF PORCINE PARTHENOGENETIC EMBRYOS." Reproduction, Fertility and Development 26, no. 1 (2014): 162. http://dx.doi.org/10.1071/rdv26n1ab96.
Повний текст джерелаLi, Y., M. L. Day, and C. O'Neill. "235.PAF induced changes in intracellular Ca2+ and membrane potential in the 2-cell mouse embryo." Reproduction, Fertility and Development 16, no. 9 (2004): 235. http://dx.doi.org/10.1071/srb04abs235.
Повний текст джерелаGenet, Marion, and Maria-Elena Torres-Padilla. "The molecular and cellular features of 2-cell-like cells: a reference guide." Development 147, no. 16 (August 15, 2020): dev189688. http://dx.doi.org/10.1242/dev.189688.
Повний текст джерелаPratt, H. P., and A. L. Muggleton-Harris. "Cycling cytoplasmic factors that promote mitosis in the cultured 2-cell mouse embryo." Development 104, no. 1 (September 1, 1988): 115–20. http://dx.doi.org/10.1242/dev.104.1.115.
Повний текст джерелаSun, Jian Hong, Yong Zhang, Bao Ying Yin, Ji Xia Li, Gen Sheng Liu, Wei Xu, and Shuang Tang. "Differential expression of Axin1, Cdc25c and Cdkn2d mRNA in 2-cell stage mouse blastomeres." Zygote 20, no. 3 (July 12, 2011): 305–10. http://dx.doi.org/10.1017/s0967199411000347.
Повний текст джерелаWurlina, Wurlina. "PENGARUH ANTIMITOSIS EKSTRAK Achyranthes Aspera Linn PADA PEMBELAHAN SEL EMBRIO (CLEAVAGE)." Berkala Penelitian Hayati 11, no. 2 (June 30, 2006): 161–65. http://dx.doi.org/10.23869/bphjbr.11.2.200610.
Повний текст джерелаForlani, S., C. Bonnerot, S. Capgras, and J. F. Nicolas. "Relief of a repressed gene expression state in the mouse 1-cell embryo requires DNA replication." Development 125, no. 16 (August 15, 1998): 3153–66. http://dx.doi.org/10.1242/dev.125.16.3153.
Повний текст джерелаChen, C. H., T. A. Lin, H. Y. Su, Y. S. Sung, L. J. Sung, S. C. Wu, W. T. K. Cheng, et al. "157 AGGREGATION AND DEVELOPMENT OF RABBIT CLONED EMBRYOS WITH ZYGOTIC, TETRAPLOID, AND PARTHENOGENETIC EMBRYO IN VITRO." Reproduction, Fertility and Development 22, no. 1 (2010): 237. http://dx.doi.org/10.1071/rdv22n1ab157.
Повний текст джерелаДисертації з теми "2 cell-Embryo"
Patel, M. "The charecterisation of the adenovirus 2-E1 genes that transform normal rat embryo fibroblasts to immortal cell lines." Thesis, University of Essex, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381249.
Повний текст джерелаPatel, M. "The characterisation of the adenovirus 2-E1 genes that transform normal rat embryo fibroblasts to immortal cell lines." Thesis, University of Essex, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332650.
Повний текст джерелаLu, Fu-i. "Control of cell movements and early patterning of the zebrafish (Danio rerio) embryo by Angiomotin like 2 and Frz." Université Louis Pasteur (Strasbourg) (1971-2008), 2007. https://publication-theses.unistra.fr/public/theses_doctorat/2007/LU_Fu-I_2007.pdf.
Повний текст джерелаI analyzed the function of two genes, Angiomotin like 2 (Amotl2) and FrzA (SFRP1, Secreted Frizzled Related Protein 1) and demonstrated that they play an essential role in controlling the cell fates and cell movements during the embryogenesis of the zebrafish (Danio rerio). Amotl2 is involved in the control of embryonic cell movements. I demontrated that Amotl2 interacts preferentially with and facilitates outward translocation of the phosphorylated c-Src, which may in turn regulates the membrane architecture. Amotl2 is under the control of the FGF signaling pathway and this gene is also required for the patterning of the embryo. Preliminary data suggest that Amotl2 is required for the secretion of Wnt8. FrzA is also required for proper cell movements and embryo patterning. Analysis of FrzA function indicates that this gene negatively regulates maternal β-catenin signaling. FrzA appeard to act in a paracrine manner and acts at short range. I established that FrzA acitivity is different from those of FrzB and DKK1. Furthermore, I showed that the inhibition of the maternal β-catenin signaling by FrzA is mediated by the Frizzled 2 receptor
Cortés, Albarracín Paola Andrea 1990. "Investigating the role of transcription factor Nkx1-2 in mouse embryonic stem cell pluripotency, self-renewal and differentiation." Doctoral thesis, Universitat Pompeu Fabra, 2019. http://hdl.handle.net/10803/668122.
Повний текст джерелаLas células embrionarias de ratón (ESCs), requieren de señales extracelulares para inducir la expresión de factores intrínsecos de pluripotencia: Oct4, Sox2 y Nanog, conocidos como la tríada OSN. Notablemente la vía de señalización Wnt/beta catenina, ha demostrado ser crucial en el control de la expresión génica de factores de transcripción en ESCs. Hasta ahora los mecanismos mediante los cuales, la vía de señalización Wnt (via Tcf3) contribuyen a potencializar el mantenimiento de las ESCs en su estado característico, no han sido esclarecidos. Además, muy poco se sabe sobre la identidad de los genes diana dependientes de Wnt y cómo regulan el estado pluripotente de las ESCs. Para identificar estos factores de transcripción (FT) reguladores dependientes de Wnt, hemos usado una estrategia inversa que nos ha ayudado a identificar FTs, cuya función en las ESCs es desconocida. El trabajo presentado en esta tesis se enfoca en investigar la función del gen no descrito hasta la fecha Nkx1-2, en el control de la pluripotencia de las ESCs. Hemos descubierto que Nkx1-2 tiene funciones duales en las células embrionarias de ratón. De hecho, Nkx1-2 puede retrasar la diferenciación de las células en ausencia de LIF, y su deleción causa una expresión aberrante de los factores importantes en mantener la pluripotencia. Además, Nkx1-2 es importante para la diferenciación apropiada de las células madre y también lo es en la especificación celular durante el desarrollo embrionario. En general, el trabajo en esta tesis revela una nueva función para Nkx1-2 en la pluripotencia y diferenciación de las células madre embrionarias de ratón.
Shajahan, Shireen. "Z-DNA drives Zscan4-dependent chromatin reorganization to induce and safeguard totipotent stem cell identity." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS221.pdf.
Повний текст джерелаMammalian development is characterized by a sequence of cell fate decisionsalong an irreversible pathway of restricted developmental potential and increasingcell specialization. With progressing development, a gradual restriction inpotency is accompanied by significant transcriptome modulation and drasticchromatin reprogramming. Totipotent 2-cell (2C) embryos are defined by aunique transcriptional signature and a relaxed chromatin organization (globalhypomethylation, poor chromatin organization and increased chromatinaccessibility). However, how 2C embryos safeguard their strict cell identity in arelaxed chromatin conformation remains poorly understood.The spontaneous conversion of mouse embryonic stem cells (mESCs) to a 2C-like state, called 2C like cells (2CLCs), provides a convenient in vitro modelsystem to study totipotent-like characteristics as they share several features with2C embryos. To investigate genome-wide chromatin interactions, chromosomeconformation capture experiments (Hi-C) were conducted in both mESCs and2CLCs. While the global chromosome architecture remained stable between thetwo cell populations, we identified new large interacting regions specific to2CLCs, located towards one end of numerous chromosomes. The formation ofthese chromatin interactions depends on Zscan4, a transcription factor expressedspecifically at the 2C stage. Intriguingly, Zscan4 binds to motifs predisposed toadopt a Z-DNA conformation, characterized by a left-handed double helix. Wedetected the presence of Z-DNA in 2CLCs, and inducing it significantly increasedthe proportion of 2CLCs displaying chromatin conformation akin to spontaneous2CLCs. Mechanistically, we propose that Z-DNA formation plays a role inaltering DNA replication timing, a process known to promote cell transitions.In summary, we propose a novel role for Zscan4 in forming 3D genomeinteraction, a process that may be critical in establishing and maintainingtotipotency
Maire, Marie-Aline. "Inhibition de l'apoptose comme facteur de la transformation morphologique des cellules embryonnaires de hamster Syrien." Metz, 2004. http://docnum.univ-lorraine.fr/public/UPV-M/Theses/2004/Maire.Marie_Aline.SMZ0434.pdf.
Повний текст джерелаApoptosis, a cell suicide pathway, is implicated in various physiological events, in particular the elimination of damaged cells. The defective regulation of apoptosis may contribute to the etiology of cancer and the impairment of normal cell death process has been implicated in neoplastic transformation. In order to test the hypothesis of a relationship between apoptosis and neoplastic transformation, we studied three chemicals, zinc as inhibitor of apoptosis, DEHP (di-2-ethylhexyl phtalate) which induced cell transformation and 2,4-D (2,4-dichlorodiphénoxyacetic acid), a peroxysome proliferators such DEHP. First, we demonstrated that anti-apoptotic chemicals (zinc and DEHP) induced SHE cell transformation. These results were in agreement with the theory of a relationship between the inhibition of apoptosis and the induction of cell transformation. However, 2,4-D induced SHE cell transformation while it has no effect on apoptosis. Second, we showed that zinc and DEHP inhibited apoptosis through an increase of the bcl-2/bax ratio. Results concerning the involvement of the proto-oncogene c-myc in apoptosis and in cell transformation are more complex. We showed that 2,4-D induced c-myc expression at concentrations which induced cell transformation. On the opposite, DEHP decreased c-myc expression which could be related to the increase of the Bcl-2 expression
Ferraz, Gustavo Dantas. "A proteção do direito fundamental à vida e as pesquisas com células-tronco embrionárias humanas no ordenamento jurídico brasileiro." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/2/2134/tde-07022011-154645/.
Повний текст джерелаThe present work deals with the debate about the beginning of the protection of the right to life and the consequences of this protection related to human embryo-based stem cell research, authorized by the Brazilian legal legislation according to the Article 5 of Law no. 11.105/2005, considered constitutional by the Federal Supreme Court in the concentrated model of constitutional control. The approach, centralized in the study of the doctrine, legislation and jurisprudence, is based on a predominantly dogmatic legal nature, in the analytical, empirical and regulatory dimensions. Following are the main conclusions: the right to life grated by the Federal Constitution structurally consists of a principle, with a broad protection scope, that justifies the need of weighting with other values protected by the legal legislation for its application; among the possible interpretations of what this right is consistent of, it can be considered as a right to the existence itself, a right to a decent life and a right to protection facing the development of the biotechnology; the beginning of the protection of the right to human embryo-based stem cell research and therapies are set in the Brazilian Law by national and international precepts, such as the American Convention of Human Rights, the Federal Constitution and the Law nº 11.105/2005; the fact that the Federal Supreme Court considered the Article 5 of Law nº 11.105/2005, in the concentrated model of constitutional control, did not distract the application of the American Convention of Human Rights (which contains the regulations that protects the right to life, in general, from its conception) neither obstructed an actual state or international control on the human embryo-based stem cell research and therapies in order to protect, among other aspects, the right to life in a transindividual approach.
Zabihi, Sheller. "Fetal Outcome in Experimental Diabetic Pregnancy." Doctoral thesis, Uppsala University, Department of Medical Cell Biology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8739.
Повний текст джерелаWomen with pregestational diabetes have a 2-5 fold increased risk of giving birth to malformed babies compared with non-diabetic women. Diabetes-induced oxidative stress in maternal and embryonic tissues has been implicated in the teratogenic process. The malformations are likely to be induced before the seventh week of pregnancy, when the yolk sac is partly responsible for the transfer of metabolites to the embryo, and the uterine blood flow to the implantation site determines the net amount of nutrients available to the conceptus. We aimed to evaluate the effect on embryogenesis caused by a diabetes-induced disturbance in yolk sac morphology, uterine blood flow or altered maternal antioxidative status in conjunction with a varied severity of the maternal diabetic state.
We investigated to which extent maternal diabetes with or without folic acid (FA) supplementation affects mRNA levels and protein distribution of ROS scavenging enzymes (SOD, CAT, GPX), vascular endothelial growth factor-A (Vegf-A), folate binding protein-1 (Folbp-1), and apoptosis associated proteins (Bax, Bcl-2, Caspase-3) in the yolk sacs of rat embryos on gestational days 10 and 11. We found that maternal diabetes impairs, and that FA supplementation restores, yolk sac vessel morphology, and that maternal diabetes is associated with increased apoptotic rate in embryos and yolk sacs, as well as impaired SOD gene expression. We assessed uterine blood flow with a laser-Doppler-flow-meter and found increased blood flow to implantation sites of diabetic rats compared with controls. Furthermore, resorbed and malformed offspring showed increased and decreased blood flow to their implantation sites, respectively. In mice with genetically altered CuZnSOD levels, maternal diabetes increased embryonic dysmorphogenesis irrespective of CuZnSOD expression. We thus found the maternal diabetic state to be a major determinant of diabetic embryopathy and that the CuZnSOD status exerts a partial protection for the embryo in diabetic pregnancy.
Cimafranca, Melissa Antonio. "2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and epidermal growth factor (EGF) signaling inhibits in vitro adipogenesis in the mouse embryo fibroblast cell line C3H10T1/2." 2006. http://catalog.hathitrust.org/api/volumes/oclc/85783754.html.
Повний текст джерелаКниги з теми "2 cell-Embryo"
1942-, Harris Stephen E., and Mansson Per-Erik, eds. Cellular factors in development and differentiation: Embryos, teratocarcinomas, and differentiated tissues : proceedings of the Third International Symposium on Cellular Endocrinology, held at Lake Placid, New York, August 30-September 2, 1987. New York: Liss, 1988.
Знайти повний текст джерелаUnited States. Congress. Senate. Committee on Appropriations. Subcommittee on Departments of Labor, Health and Human Services, Education, and Related Agencies. Stem cell research: Hearings before a subcommittee of the Committee on Appropriations, United States Senate, One Hundred Fifth Congress, second session, special hearing, December 2, 1998, Washington DC, January 12, 1999, Washington DC, January 26, 1999, Washington DC. Washington: U.S. G.P.O., 1999.
Знайти повний текст джерелаGerm cell protocols. Vol. 2, Molecular embryo analysis, live imaging, transgenesis, and cloning. Totowa, NJ: Humana Press, 2003.
Знайти повний текст джерелаGerm Cell Protocols : Volume 2: Molecular Embryo Analysis, Live Imaging, Transgenesis, and Cloning. Humana Press, 2004.
Знайти повний текст джерелаSchatten, Heide. Germ Cell Protocols: Volume 2: Molecular Embryo Analysis, Live Imaging, Transgenesis, and Cloning (Methods in Molecular Biology). Humana Press, 2004.
Знайти повний текст джерелаЧастини книг з теми "2 cell-Embryo"
Kong, Qingran, and Zhonghua Liu. "Electrofusion of 2-Cell Embryos for Porcine Tetraploid Embryo Production." In Methods in Molecular Biology, 361–71. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8831-0_21.
Повний текст джерелаLefèvre, Annick, and Thierry Blachère. "Methylation of Specific Regions: Bisulfite-Sequencing at the Single Oocyte or 2-Cell Embryo Level." In Methods in Molecular Biology, 209–26. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1594-1_16.
Повний текст джерелаFielmich, Lars-Eric, and Sander van den Heuvel. "Polarity Control of Spindle Positioning in the C. elegans Embryo." In Cell Polarity 2, 119–41. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14466-5_5.
Повний текст джерелаMalerczyk, Claudius, and Helmut Müller. "Purified Chick-Embryo Cell Vaccine." In Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention, Volume 2, 251–60. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-801919-1.00020-8.
Повний текст джерелаEttensohn, Charles A., Kirsten A. Guss, Katherine M. Malinda, Roberta N. Miller, and Seth W. Ruffins. "Cell Interactions in the Sea Urchin Embryo." In Advances in Developmental Biochemistry, 47–98. Elsevier, 1996. http://dx.doi.org/10.1016/s1064-2722(08)60057-2.
Повний текст джерелаSlack, Jonathan. "2. Embryonic stem cells." In Stem Cells: A Very Short Introduction, 21–37. Oxford University Press, 2021. http://dx.doi.org/10.1093/actrade/9780198869290.003.0002.
Повний текст джерелаGiordano, Simona. "Cloning." In Routledge Encyclopedia of Philosophy. London: Routledge, 2020. http://dx.doi.org/10.4324/9780415249126-l142-2.
Повний текст джерелаJeske, Mandy, and Elmar Wahle. "Chapter 6 Cell‐Free Deadenylation Assays with Drosophila Embryo Extracts." In Methods in Enzymology, 107–18. Elsevier, 2008. http://dx.doi.org/10.1016/s0076-6879(08)02606-2.
Повний текст джерелаJohnson, Randall, and Nigel Killeen. "Gene targeting in mammalian cells." In Gene probes 2, 1–30. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780199634156.003.0012.
Повний текст джерелаKöhler, Almut, Alexandra Schambony, and Doris Wedlich. "Cell migration under control of Wnt‐signaling in the vertebrate embryo." In Wnt Signaling in Embryonic Development, 159–201. Elsevier, 2007. http://dx.doi.org/10.1016/s1574-3349(06)17005-2.
Повний текст джерелаТези доповідей конференцій з теми "2 cell-Embryo"
Koloskova, E. M., V. A. Ezerskii, and T. P. Trubitsina. "Effect of microinjection of CRISPR / Cas9 components in plasmid form on the development of rabbit embryos during in vitro culture." In CURRENT STATE, PROBLEMS AND PROSPECTS OF THE DEVELOPMENT OF AGRARIAN SCIENCE. Federal State Budget Scientific Institution “Research Institute of Agriculture of Crimea”, 2020. http://dx.doi.org/10.33952/2542-0720-2020-5-9-10-131.
Повний текст джерелаNerurkar, Nandan L., and Cliff J. Tabin. "Collective Cell Movements Drive Morphogenesis and Elongation of the Avian Hindgut." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14438.
Повний текст джерелаPehl-De Silva, Aruni T., Preethi Samala, Hongkyu Lee, and Joseph R. Landolph. "Abstract 3466: Increased steady-state levels of microtubules in aberrant distributions in Ni+2ion-/MCA-transformed C3H/10T1/2 mouse embryo cell lines." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3466.
Повний текст джерелаFilas, Benjamen A., Gang Xu, Andrew K. Knutsen, Philip V. Bayly, and Larry A. Taber. "Morphogenetic and Residual Strains in the Embryonic Chick Brain." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-191781.
Повний текст джерелаYao, Jiang, Jonathan M. Young, Benjamen A. Filas, Nils Klinkenberg, Jincheng Wang, Larry A. Taber, and Renato Perucchio. "Finite Element Modeling of the Tubular Embryonic Chick Heart With Smoothed Surfaces and Contact With Splanchnopleure Membrane." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206466.
Повний текст джерелаHart, Stephen A., and Marcelo J. Dapino. "Accelerated Bone Growth Remotely Induced by Magnetic Fields and Smart Materials." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-175966.
Повний текст джерелаChun, Young Wook, Joey Barnett, and W. David Merryman. "Aortic Valve Interstitial Cell Activation Does Not Occur at Low Tissue Stiffness During Embryogenesis." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80501.
Повний текст джерелаЗвіти організацій з теми "2 cell-Embryo"
Petitte, James, Hefzibah Eyal-Giladi, and Malka Ginsburg. The Study of Primordial Germ Cell Development as a Tool for Gene Transfer in Chickens. United States Department of Agriculture, October 1991. http://dx.doi.org/10.32747/1991.7561071.bard.
Повний текст джерелаHalevy, Orna, Zipora Yablonka-Reuveni, and Israel Rozenboim. Enhancement of meat production by monochromatic light stimuli during embryogenesis: effect on muscle development and post-hatch growth. United States Department of Agriculture, June 2004. http://dx.doi.org/10.32747/2004.7586471.bard.
Повний текст джерелаHansen, Peter J., and Zvi Roth. Use of Oocyte and Embryo Survival Factors to Enhance Fertility of Heat-stressed Dairy Cattle. United States Department of Agriculture, August 2011. http://dx.doi.org/10.32747/2011.7697105.bard.
Повний текст джерелаOhad, Nir, and Robert Fischer. Regulation of Fertilization-Independent Endosperm Development by Polycomb Proteins. United States Department of Agriculture, January 2004. http://dx.doi.org/10.32747/2004.7695869.bard.
Повний текст джерелаYahav, Shlomo, John Brake, and Orna Halevy. Pre-natal Epigenetic Adaptation to Improve Thermotolerance Acquisition and Performance of Fast-growing Meat-type Chickens. United States Department of Agriculture, September 2009. http://dx.doi.org/10.32747/2009.7592120.bard.
Повний текст джерела