Готові списки джерел за темами / 12/14/12-helix

Добірка наукової літератури з теми "12/14/12-helix"

Автор: Grafiati

Опубліковано: 6 вересня 2023

Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями

Оберіть тип джерела:

Зміст

Статті в журналах

Ознайомтеся зі списками актуальних статей, книг, дисертацій, тез та інших наукових джерел на тему "12/14/12-helix".

Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.

Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.

Статті в журналах з теми "12/14/12-helix"

Wu, Yun-Dong, та De-Ping Wang. "Theoretical Study on Side-Chain Control of the 14-Helix and the 10/12-Helix of β-Peptides". Journal of the American Chemical Society 121, № 40 (жовтень 1999): 9352–62. http://dx.doi.org/10.1021/ja990955l.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Milbeo, Pierre, Matthieu Simon, Claude Didierjean, Emmanuel Wenger, Emmanuel Aubert, Jean Martinez, Muriel Amblard, Monique Calmès, and Baptiste Legrand. "A bicyclic unit reversal to stabilize the 12/14-helix in mixed homochiral oligoureas." Chemical Communications 56, no. 57 (2020): 7921–24. http://dx.doi.org/10.1039/d0cc02902e.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Legrand, Baptiste, Christophe André, Laure Moulat, Claude Didierjean, Patrick Hermet, Jean-Louis Bantignies, Jean Martinez, Muriel Amblard та Monique Calmès. "12/14/14-Helix Formation in 2:1 α/β-Hybrid Peptides Containing Bicyclo[2.2.2]octane Ring Constraints". Chemistry - A European Journal 22, № 34 (14 липня 2016): 11986–90. http://dx.doi.org/10.1002/chem.201602746.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Tittelbach, Michael, and Tobias Diener. "Orsiro – The First Hybrid Drug-eluting Stent, Opening Up a New Class of Drug-eluting Stents for Superior Patient Outcomes." Interventional Cardiology Review 6, no. 2 (2011): 142. http://dx.doi.org/10.15420/icr.2011.6.2.142.

Повний текст джерела

Анотація:

The Orsiro device is a hybrid drug-eluting stent that represents a new strategy in the treatment of coronary artery stenosis. Orsiro features a hybrid coating of passive and active components: the PROBIO passive coating seals the metal surface of the stent and prevents interaction with the surrounding blood and tissue, while the BIOlute active coating contains a highly biocompatible polymer that delivers a -limus drug over 12–14 weeks and degrades gently over one to two years, thereby avoiding increased inflammation. The stent backbone is the PRO-Kinetic Energy platform, which has a double-helix stent design and thin struts, bringing flexibility and ease of deliverability.

Стилі APA, Harvard, Vancouver, ISO та ін.

Kurz, E. M., T. W. Holstein, B. M. Petri, J. Engel, and C. N. David. "Mini-collagens in hydra nematocytes." Journal of Cell Biology 115, no. 4 (November 15, 1991): 1159–69. http://dx.doi.org/10.1083/jcb.115.4.1159.

Повний текст джерела

Анотація:

We have isolated and characterized four collagen-related c-DNA clones (N-COL 1, N-COL 2, N-COL 3, N-COL 4) that are highly expressed in developing nematocytes in hydra. All four c-DNAs as well as their corresponding transcripts are small in size (600-1,000 bp). The deduced amino acid sequences show that they contain a central region consisting of 14 to 16 Gly-X-Y triplets. This region is flanked amino-terminal by a stretch of 14-23 proline residues and carboxy-terminal by a stretch of 6-9 prolines. At the NH2- and COOH-termini are repeated patterns of cysteine residues that are highly conserved between the molecules. A model is proposed which consists of a central stable collagen triple helix of 12-14 nm length from which three 9-22 nm long polyproline II type helices emerge at both ends. Disulfide linkage between cysteine-rich segments in these helices could lead to the formation of oligomeric network structures. Electrophoretic characterization of nematocyst extracts allows resolution of small proline-rich polypeptides that correspond in size to the cloned sequences.

Стилі APA, Harvard, Vancouver, ISO та ін.

LECONA, Emilio, Javier TURNAY, Nieves OLMO, Ana GUZMÁN-ARÁNGUEZ, Reginald O. MORGAN, Maria-Pilar FERNANDEZ, and Ma Antonia LIZARBE. "Structural and functional characterization of recombinant mouse annexin A11: influence of calcium binding." Biochemical Journal 373, no. 2 (July 15, 2003): 437–49. http://dx.doi.org/10.1042/bj20021721.

Повний текст джерела

Анотація:

Annexin A11 is one of the 12 vertebrate subfamilies in the annexin superfamily of calcium/phospholipid-binding proteins, distinguishable by long, non-homologous N-termini rich in proline, glycine and tyrosine residues. As there is negligible structural information concerning this annexin subfamily apart from primary sequence data, we have cloned, expressed and purified recombinant mouse annexin A11 to investigate its structural and functional properties. CD spectroscopy reveals two main secondary-structure contributions, α-helix and random coil (approx. 30% each), corresponding mainly to the annexin C-terminal tetrad and the N-terminus respectively. On calcium binding, an increase in α-helix and a decrease in random coil are detected. Fluorescence spectroscopy reveals that its only tryptophan residue, located at the N-terminus, is completely exposed to the solvent; calcium binding promotes a change in tertiary structure, which does not affect this tryptophan residue but involves the movement of approximately four tyrosine residues to a more hydrophobic environment. These calcium-induced structural changes produce a significant thermal stabilization, with an increase of approx. 14 °C in the melting temperature. Annexin A11 binds to acidic phospholipids and to phosphatidylethanolamine in the presence of calcium; weaker calcium-independent binding to phosphatidylserine, phosphatidic acid and phosphatidylethanolamine was also observed. The calcium-dependent binding to phosphatidylserine is accompanied by an increase in α-helix and a decrease in random-coil contents, with translocation of the tryptophan residue towards a more hydrophobic environment. This protein induces vesicle aggregation but requires non-physiological calcium concentrations in vitro. A three-dimensional model, consistent with these data, was generated to conceptualize annexin A11 structure–function relationships.

Стилі APA, Harvard, Vancouver, ISO та ін.

Alway, Stephen E., Julie K. Martyn, Jun Ouyang, Archana Chaudhrai, and Zsolt S. Murlasits. "Id2 expression during apoptosis and satellite cell activation in unloaded and loaded quail skeletal muscles." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 284, no. 2 (February 1, 2003): R540—R549. http://dx.doi.org/10.1152/ajpregu.00550.2002.

Повний текст джерела

Анотація:

Inhibitor of differentiation-2 (Id2) is a basic helix-loop-helix protein that acts as a negative regulator of the myogenic regulatory transcription factor family, but Id2 has also been implicated in apoptosis in several cell lines. In this study, we tested the hypothesis that Id2 has a role in both apoptosis-associated muscle atrophy and muscle hypertrophy. A weight corresponding to 12% of the body weight was attached to one wing of Japanese quail to induce hypertrophy in the patagialis (PAT) muscle. Birds in group 1 were killed after 5 ( n = 8), 7 ( n = 10), or 14 days ( n = 10) of loading. The left wing was loaded for 14 days in group 2 birds, and then the weight was removed and the PAT was examined after 7 ( n = 10), 14 ( n = 10), or 21 ( n = 5) days of unloading. A time-released bromodeoxyuridine (BrdU) pellet was implanted subcutaneously with wing weighting to identify activated satellite cells during loading. The left wing was loaded for 14 days, unloaded for 14 days, and then the weight was reattached for a subsequent 7 ( n = 10) or 14 days ( n = 10) in group 3 birds. BrdU was implanted on the second loading phase in this group. Id2 mRNA as measured by kinetic PCR increased by 3.9-, 2.7-, and 1.6-fold, relative to control levels after 7, 14, and 21 days of unloading ( group 2). Id2 protein as estimated by Western blots increased by 1.5-, 1.4-, and 0.75-fold after 7, 14, and 21 days of unloading ( group 2). Muscle unloading induced apoptosis, because poly(ADP-ribose) polymerase-(PARP)-positive nuclei increased and caspase 8 levels increased by 2.6- and 1.7-fold after 7 or 14 days of unloading, respectively ( group 2). Although BrdU-positive nuclei increased during loading ( groups 1 and 3), 50% failed to survive during unloading ( group 2). Id2 mRNA increased by 2.2- and 1.8-fold after 5 and 7 days of loading, respectively, but decreased to control levels by 14 days of loading in group 1. Id2 protein levels increased 2.1-fold after 5 days of loading ( group 1). In contrast, Id2 did not increase in reloaded muscles of group 3 birds. These data suggest that Id2 may have a role in apoptosis-associated atrophy of skeletal muscles, but its role in muscle hypertrophy is less clear.

Стилі APA, Harvard, Vancouver, ISO та ін.

Lin, Weida, Yueling Li, Qiuwei Lu, Hongfei Lu, and Junmin Li. "Combined Analysis of the Metabolome and Transcriptome Identified Candidate Genes Involved in Phenolic Acid Biosynthesis in the Leaves of Cyclocarya paliurus." International Journal of Molecular Sciences 21, no. 4 (February 17, 2020): 1337. http://dx.doi.org/10.3390/ijms21041337.

Повний текст джерела

Анотація:

To assess changes of metabolite content and regulation mechanism of the phenolic acid biosynthesis pathway at different developmental stages of leaves, this study performed a combined metabolome and transcriptome analysis of Cyclocarya paliurus leaves at different developmental stages. Metabolite and transcript profiling were conducted by ultra-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometer and high-throughput RNA sequencing, respectively. Transcriptome identification showed that 58 genes were involved in the biosynthesis of phenolic acid. Among them, 10 differentially expressed genes were detected between every two developmental stages. Identification and quantification of metabolites indicated that 14 metabolites were located in the phenolic acid biosynthetic pathway. Among them, eight differentially accumulated metabolites were detected between every two developmental stages. Association analysis between metabolome and transcriptome showed that six differentially expressed structural genes were significantly positively correlated with metabolite accumulation and showed similar expression trends. A total of 128 transcription factors were identified that may be involved in the regulation of phenolic acid biosynthesis; these include 12 MYBs and 10 basic helix–loop–helix (bHLH) transcription factors. A regulatory network of the phenolic acid biosynthesis was established to visualize differentially expressed candidate genes that are involved in the accumulation of metabolites with significant differences. The results of this study contribute to the further understanding of phenolic acid biosynthesis during the development of leaves of C. paliurus.

Стилі APA, Harvard, Vancouver, ISO та ін.

Sahu, Meman, Amit Kumar Manna, Dinesh De, and Goutam Kumar Patra. "Synthesis, characterization, X-ray crystal structure and Hirshfeld surface analysis of Ni(II) complex of 1,2-bis(pyridin-2-ylmethylene)hydrazine." European Journal of Chemistry 13, no. 1 (March 31, 2022): 1–7. http://dx.doi.org/10.5155/eurjchem.13.1.1-7.2166.

Повний текст джерела

Анотація:

We report the synthesis, characterization, X-ray crystal structure and Hirshfeld surface analysis of Ni(II) perchlorate complex (1, Ni2L3·4ClO4·2CH3CN) of 1,2-bis(pyridin-2-ylmethylene)hydrazine (L) ligand. The X-ray crystallographic study of complex 1 reveals that in the presence of Ni(II) ions,the ligand L forms a dimeric triple helix with a Ni(II)-Ni(II) distance of 3.794 Å. Crystal data for C40H36Cl4N14Ni2O16: Monoclinic, space group P21/c (no. 14), a = 20.7558(19) Å, b = 13.1937(12) Å, c = 20.0181(18) Å, β = 96.9510(10)°, V = 5441.6(9) Å3, Z = 4, T = 293.15 K, μ(MoKα) = 0.965 mm-1, Dcalc = 1.498 g/cm3, 38075 reflections measured (1.976° ≤ 2Θ ≤ 43.728°), 6557 unique (Rint = 0.0695, Rsigma = 0.0466) which were used in all calculations. The final R1 was 0.0518 (I > 2σ(I)) and wR2 was 0.1270 (all data). The Hirshfeld surface analysis of complex 1 shows that C···H, H···H, N···H and O···H interactions of 10.9, 26.4, 6.7, and 33.4%; respectively, which exposed that the main intermolecular interactions were H···H intermolecular interactions.

Стилі APA, Harvard, Vancouver, ISO та ін.

Sharma, Gangavaram V. M., Bommagani Shoban Babu, Deepak Chatterjee, Kallaganti V. S. Ramakrishna, Ajit C. Kunwar, Peter Schramm та Hans-Jörg Hofmann. "Theoretical and Experimental Studies on α/ε-Hybrid Peptides: Design of a 14/12-Helix from Peptides with Alternating (S)-C-Linked Carbo-ε-amino Acid [(S)-ε-Caa(x)] andl-Ala". Journal of Organic Chemistry 74, № 17 (4 вересня 2009): 6703–13. http://dx.doi.org/10.1021/jo901277a.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Більше джерел

Ми пропонуємо знижки на всі преміум-плани для авторів, чиї праці увійшли до тематичних добірок літератури. Зв'яжіться з нами, щоб отримати унікальний промокод!