Готові списки джерел за темами / (1,3;1,4)-β-glucan

Добірка наукової літератури з теми "(1,3;1,4)-β-glucan"

Автор: Grafiati

Опубліковано: 10 грудня 2022

Оновлено: 29 січня 2023

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Статті в журналах з теми "(1,3;1,4)-β-glucan"

Chang, Shu-Chieh, Rebecka Karmakar Saldivar, Pi-Hui Liang та Yves S. Y. Hsieh. "Structures, Biosynthesis, and Physiological Functions of (1,3;1,4)-β-d-Glucans". Cells 10, № 3 (27 лютого 2021): 510. http://dx.doi.org/10.3390/cells10030510.

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(1,3;1,4)-β-d-Glucans, also named as mixed-linkage glucans, are unbranched non-cellulosic polysaccharides containing both (1,3)- and (1,4)-β-linkages. The linkage ratio varies depending upon species origin and has a significant impact on the physicochemical properties of the (1,3;1,4)-β-d-glucans. (1,3;1,4)-β-d-Glucans were thought to be unique in the grasses family (Poaceae); however, evidence has shown that (1,3;1,4)-β-d-glucans are also synthesized in other taxa, including horsetail fern Equisetum, algae, lichens, and fungi, and more recently, bacteria. The enzyme involved in (1,3;1,4)-β-d-glucan biosynthesis has been well studied in grasses and cereal. However, how this enzyme is able to assemble the two different linkages remains a matter of debate. Additionally, the presence of (1,3;1,4)-β-d-glucan across the species evolutionarily distant from Poaceae but absence in some evolutionarily closely related species suggest that the synthesis is either highly conserved or has arisen twice as a result of convergent evolution. Here, we compare the structure of (1,3;1,4)-β-d-glucans present across various taxonomic groups and provide up-to-date information on how (1,3;1,4)-β-d-glucans are synthesized and their functions.

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Cseh, A., K. Kruppa, I. Molnár, M. Rakszegi, J. Doležel та M. Molnár-Láng. "Characterization of a new 4BS.7HL wheat–barley translocation line using GISH, FISH, and SSR markers and its effect on the β-glucan content of wheat". Genome 54, № 10 (жовтень 2011): 795–804. http://dx.doi.org/10.1139/g11-044.

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A spontaneous interspecific Robertsonian translocation was revealed by genomic in situ hybridization (GISH) in the progenies of a monosomic 7H addition line originating from a new wheat ‘Asakaze komugi’ × barley ‘Manas’ hybrid. Fluorescence in situ hybridization (FISH) with repetitive DNA sequences (Afa family, pSc119.2, and pTa71) allowed identification of all wheat chromosomes, including wheat chromosome arm 4BS involved in the translocation. FISH using barley telomere- and centromere-specific repetitive DNA probes (HvT01 and (AGGGAG)n) confirmed that one of the arms of barley chromosome 7H was involved in the translocation. Simple sequence repeat (SSR) markers specific to the long (L) and short (S) arms of barley chromosome 7H identified the translocated chromosome segment as 7HL. Further analysis of the translocation chromosome clarified the physical position of genetically mapped SSRs within 7H, with a special focus on its centromeric region. The presence of the HvCslF6 gene, responsible for (1,3;1,4)-β-d-glucan production, was revealed in the centromeric region of 7HL. An increased (1,3;1,4)-β-d-glucan level was also detected in the translocation line, demonstrating that the HvCslF6 gene is of potential relevance for the manipulation of wheat (1,3;1,4)-β-d-glucan levels.

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Gracia, Montilla-Bascón, Paul R. Armstrong, Han Rongkui, and Sorrells Mark. "Quantification of betaglucans, lipid and protein contents in whole oat groats (Avena sativa L.) using near infrared reflectance spectroscopy." Journal of Near Infrared Spectroscopy 25, no. 3 (June 2017): 172–79. http://dx.doi.org/10.1177/0967033517709615.

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Whole oat has been described as an important healthy food for humans due to its beneficial nutritional components. The positive health benefits of consuming oats as a whole-grain food are attributed in part to β-glucan, which has outstanding functional and nutritional properties. Near infrared reflectance spectroscopy is a powerful, fast, accurate and non-destructive analytical tool that can be substituted for some traditional chemical analysis. A total of 1728 single intact groats of six different oat varieties were scanned by near infrared spectroscopy to develop non-destructive predictions for (1,3;1,4)-β-D-glucan (β-glucan), protein and oil content in groats. Prediction models for single kernels were developed using partial least squares regression. Regression parameters between the chemical values, determined by wet-lab reference methods, and the predicted values determined from near infrared spectra, were veriﬁed by cross-validation and against data from a set of independent samples. The cross-validation correlation coefficients ( R2CV) for β-glucan, protein and oil were 0.83, 0.72 and 0.92, respectively, the root-mean-square error ranged from 0.25% to 0.60% for all compounds. Independent validation data had r2 values ranging from 0.69 to 0.95; root-mean-square error of prediction values (RMSEP) values were equal to or less than 0.52%, 0.62% and 0.27% for β-glucan, protein and oil, respectively. The data indicated that non-destructive screening of β-glucan, protein and oil contents in single kernels of dehulled oat grains from their near infrared spectra could be successfully used in breeding programs.

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Ermawar, Riksfardini A., Helen M. Collins, Caitlin S. Byrt, Natalie S. Betts, Marilyn Henderson, Neil J. Shirley, Julian Schwerdt, Jelle Lahnstein, Geoffrey B. Fincher та Rachel A. Burton. "Distribution, structure and biosynthetic gene families of (1,3;1,4)-β-glucan in Sorghum bicolor". Journal of Integrative Plant Biology 57, № 4 (31 березня 2015): 429–45. http://dx.doi.org/10.1111/jipb.12338.

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Han, Ning, Chenglong Na, Yuqiong Chai, Jianshu Chen, Zhongbo Zhang, Bin Bai, Hongwu Bian, Yuhong Zhang та Muyuan Zhu. "Over-expression of (1,3;1,4)-β -D-glucanase isoenzyme EII gene results in decreased (1,3;1,4)-β -D-glucan content and increased starch level in barley grains". Journal of the Science of Food and Agriculture 97, № 1 (13 квітня 2016): 122–27. http://dx.doi.org/10.1002/jsfa.7695.

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Christensen, Ulla, та Henrik Vibe Scheller. "Regulation of (1,3;1,4)-β-d-glucan synthesis in developing endosperm of barley lys mutants". Journal of Cereal Science 55, № 1 (січень 2012): 69–76. http://dx.doi.org/10.1016/j.jcs.2011.10.005.

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Cory, Aron T., Monica Båga, Anthony Anyia, Brian G. Rossnagel та Ravindra N. Chibbar. "Genetic markers for CslF6 gene associated with (1,3;1,4)-β-glucan concentration in barley grain". Journal of Cereal Science 56, № 2 (вересень 2012): 332–39. http://dx.doi.org/10.1016/j.jcs.2012.02.003.

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Marcotuli, Ilaria, Pasqualina Colasuonno, Yves S. Y. Hsieh, Geoffrey B. Fincher, and Agata Gadaleta. "Non-Starch Polysaccharides in Durum Wheat: A Review." International Journal of Molecular Sciences 21, no. 8 (April 22, 2020): 2933. http://dx.doi.org/10.3390/ijms21082933.

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Durum wheat is one of most important cereal crops that serves as a staple dietary component for humans and domestic animals. It provides antioxidants, proteins, minerals and dietary fibre, which have beneficial properties for humans, especially as related to the health of gut microbiota. Dietary fibre is defined as carbohydrate polymers that are non-digestible in the small intestine. However, this dietary component can be digested by microorganisms in the large intestine and imparts physiological benefits at daily intake levels of 30–35 g. Dietary fibre in cereal grains largely comprises cell wall polymers and includes insoluble (cellulose, part of the hemicellulose component and lignin) and soluble (arabinoxylans and (1,3;1,4)-β-glucans) fibre. More specifically, certain components provide immunomodulatory and cholesterol lowering activity, faecal bulking effects, enhanced absorption of certain minerals, prebiotic effects and, through these effects, reduce the risk of type II diabetes, cardiovascular disease and colorectal cancer. Thus, dietary fibre is attracting increasing interest from cereal processors, producers and consumers. Compared with other components of the durum wheat grain, fibre components have not been studied extensively. Here, we have summarised the current status of knowledge on the genetic control of arabinoxylan and (1,3;1,4)-β-glucan synthesis and accumulation in durum wheat grain. Indeed, the recent results obtained in durum wheat open the way for the improvement of these important cereal quality parameters.

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Anderson, Victoria A., Scott D. Haley, Frank B. Peairs, Leon van Eck, Jan E. Leach та Nora L. V. Lapitan. "Virus-Induced Gene Silencing Suggests (1,3;1,4)-β-glucanase Is a Susceptibility Factor in the Compatible Russian Wheat Aphid–Wheat Interaction". Molecular Plant-Microbe Interactions® 27, № 9 (вересень 2014): 913–22. http://dx.doi.org/10.1094/mpmi-05-13-0141-r.

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The Russian wheat aphid (RWA), Diuraphis noxia (Kurdjumov), is a significant insect pest of wheat (Triticum aestivum L.) and has a major economic impact worldwide, especially on winter wheat in the western United States. The continuing emergence of new RWA biotypes virulent to existing resistance genes reinforces the need for more durable resistance. Studies have indicated that resistance in previously susceptible plants can be produced by knock-down of susceptibility genes or other genes involved in host plant susceptibility. Therefore, investigation into genes involved in compatible RWA–wheat interactions could be a feasible approach to achieving durable RWA resistance. The objective of this study was to test whether silencing (1,3;1,4)-β-glucanase, previously observed to be highly induced in susceptible compared with resistant wheat during aphid infestation, would confer resistance to a susceptible wheat genotype. Barley stripe mosaic virus–mediated virus-induced gene silencing was employed to test whether (1,3;1,4)-β-glucanase is involved in the susceptible reaction of ‘Gamtoos-S' (GS). Controlled infestation with U.S. biotype RWA2 was done to assess aphid reproduction and host symptom development. Aphids on (1,3;1,4)-β-glucanase-silenced plants reproduced less per day and had longer prenymphipositional periods than those on control GS plants. Furthermore, the (1,3;1,4)-β-glucanase-silenced plants exhibited less chlorosis and greater dry weight compared with GS. Aphid reproduction and host plant symptom development showed linear relationships with (1,3;1,4)-β-glucanase transcript levels. Our results suggest that (1,3;1,4)-β-glucanase is required for successful infestation by the RWA and may be a susceptibility factor that could be exploited as a potential target for RWA resistance breeding.

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Lopez-Sanchez, Patricia, Dongjie Wang, Zhiyan Zhang, Bernadine Flanagan та Michael J. Gidley. "Microstructure and mechanical properties of arabinoxylan and (1,3;1,4)-β-glucan gels produced by cryo-gelation". Carbohydrate Polymers 151 (жовтень 2016): 862–70. http://dx.doi.org/10.1016/j.carbpol.2016.06.038.

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Дисертації з теми "(1,3;1,4)-β-glucan"

Garcia, Gimenez Guillermo. "Regulation of (1,3;1,4)-β-glucan synthesis in barley (Hordeum vulgare L.)". Thesis, University of Dundee, 2019. https://discovery.dundee.ac.uk/en/studentTheses/fc549364-8ed1-4840-ad6c-b868cfebb28b.

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Schreiber, Miriam. "Identification of genes involved in (1,3;1,4)-β-glucan synthesis in barley (Hordeum vulgare)". Thesis, University of Dundee, 2016. https://discovery.dundee.ac.uk/en/studentTheses/5e459c3c-9ba7-4fb6-a33b-02577ea185fa.

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Agbenorhevi, Jacob Kwaku. "Phase behaviour of oat β-glucan/sodium caseinate mixtures". Thesis, University of Huddersfield, 2011. http://eprints.hud.ac.uk/id/eprint/17475/.

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Oat β-glucan is a water soluble polysaccharide which has been approved as a functional bioactive ingredient. In this thesis, β-glucan was successfully isolated from oat flour and samples of different molecular weights were produced. The structural features and molecular weights(Mw) were characterized by 13C–NMR spectroscopy and high performance size-exclusion chromatography, respectively. The rheological properties and microstructure of aqueous oat β-glucan solutions were investigated by rheometry and atomic force microscopy (AFM),respectively. The samples with β-glucan content between 78-86 % on a dry weight basis had Mw, intrinsic viscosity ([η]) and critical coil overlap concentration (c*) in the range of 142 - 2800 x 103 g/mol, 1.7 - 7.2 dL/g and 0.25 - 1.10 g/dL, respectively. The flow and viscoelasticvbehaviour was highly dependent on Mw and on the concentration of the β-glucan solutions. AFM images revealed the formation of cluster or aggregates linked via individual polymer chains scattered heterogeneously throughout the system. The aggregate size was also dependent on molecular weight of the samples and influences the rheological behaviour of β-glucan solutions. The isothermal phase behaviour at 5 oC of β-glucan/sodium caseinate mixtures were investigated by means of phase diagram construction, rheometry, electrophoresis and fluorescence microscopy. Phase diagrams indicated that the compatibility of the β-glucan/sodium caseinate system increases as β-glucan Mw decreases. Images of the mixtures taken at various biopolymer concentrations revealed phase separation with the presence of β-glucan aggregates,whose size depends on Mw and concentration. At the same protein concentration in the mixtures, the viscosity increases with increasing Mw and concentration of β-glucan. However, the results also revealed that in the state of thermodynamic equilibrium with comparable polymer concentrations in mixture, the lower Mw samples yielded similar or higher viscosity. At equivalent hydrodynamic volume of β-glucan component in the mixture, all the samples exhibited similar viscosity/flow behaviour. A deviation dependent on the protein concentration was observed for the high Mw sample in the concentrated regime due to the size of the β-glucan aggregates formed. Results demonstrate that by controlling the structural features of β-glucan in mixture with sodium caseinate, informed manipulation of rheological properties in these systems can be achieved.

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Granum, Espen. "Metabolism and function of β-1,3-glucan in marine diatoms". Doctoral thesis, Norwegian University of Science and Technology, Faculty of Natural Sciences and Technology, 2002. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-44.

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β-1,3-Glucan (chrysolaminaran) is the principal storage polysaccharide in diatoms (Bacillariophyceae), the major primary producers in the sea. The glucan generally contributes a substantial fraction of the algal biomass, but its level varies markedly in response to growth conditions. The scope of this work was to study the metabolism and function of the polysaccharide in marine diatoms. Axenic cultures of the marine planktonic diatom Skeletonema costatum (Grev.) Cleve were used in the experiments. Glucan metabolism was studied by growing the alga in batch culture, and measuring metabolite fluxes by chemical analyses as well as by ¹⁴C tracer technique using labeled bicarbonate. A photobioreactor was developed for strictly controlled growth of microalgae. Fine pH regulation was obtained by relay-activated titration with dilute acid (HCl) and base (NaOH). Irradiance and temperature were also carefully controlled. Batch cultures were grown with a 14:10 h light:dark cycle, and pH curves were recorded during different growth phases.

A new method was developed for the combined determination of β-1,3-glucan and cell wall polysaccharides in diatoms, representing total cellular carbohydrate. The glucan is rapidly extracted by hot dilute H₂SO₄, and the cell wall polysaccharides are subsequently hydrolyzed by cold 80% H₂SO₄overnight. Each carbohydrate fraction is finally determined by the phenol-sulphuric acid method. This procedure is simple and rapid compared to previous methods, and applies well to laboratory cultures as well as natural phytoplankton populations dominated by diatoms.

Synthesis and mobilization of β-1,3-glucan in N-limited S. costatum were studied by combined ¹⁴C tracer technique and chemical analyses. Radiolabeled bicarbonate was added to the cultures, and ¹⁴C incorporation in different metabolites was determined using biochemical fractionation. In a pulse phase, ¹⁴C label was mainly incorporated in the glucan fraction (85%) during photosynthesis under nitrogen limitation. Subsequently, a ¹⁴C chase was carried out by adding NH₄⁺ and incubating the cells under different light conditions. Radiolabeled glucan decreased significantly (by 26% in the dark, and by 19% in low light) whereas radiolabeled amino acids, proteins and other polysaccharides increased significantly during NH₄⁺ assimilation. Chemical analyses of β-1,3-glucan and cellular free amino acids supported the¹⁴C measurements. Changes in amino acid composition strongly indicated that de novo biosynthesis took place, with a Gln/Glu ratio increasing from 0.4 to 10. This study provides new evidence of β-1,3-glucan supplying carbon skeletons for synthesis of amino acids and protein in diatoms. Mobilization of glucan yields glucose, which is further metabolized by the respiratory pathways to provide precursors as well as energy. The results from the ¹⁴C chase also indicated significant synthesis of other polysaccharides or possibly RNA from glucan.

In a different study, dark carbon fixation in N-limited S. costatum was measured using ¹⁴C-bicarbonate. Addition of NH₄⁺ resulted in 4-fold increase in carboxylation rate, and biochemical fractionation showed that mainly amino acids were radiolabeled. Chemical analyses confirmed that cellular free amino acids increased rapidly (with increasing Gln/Glu), and showed that cellular glucan decreased significantly (by 28%) during NH4+ assimilation. The results strongly indicate that β-carboxylation provides C⁴ precursors for amino acid synthesis, and β-1,3-glucan is likely to be the ultimate substrate for β-carboxylation. Moreover, a C/N uptake ratio of 0.33 indicated that β-carboxylation was related to protein synthesis.

A detailed study was made of the production of carbohydrates and amino acids by S. costatum during different growth phases. During exponential growth under diel light conditions, the glucan level oscillated between 17% (end of scotophase) and 42% (end of photophase) of cellular organic carbon, and the corresponding protein/glucan ratio alternated between 2.3 and 0.7. Concurrently, the cellular free amino acid pool oscillated between 8% (end of scotophase) and 22% (end of photophase) of cellular organic nitrogen, and the corresponding Gln/Glu ratio alternated between 0.05 and 2. Depletion of nitrogen from the medium resulted in rapid accumulation of glucan, reaching 75-80% of cellular organic carbon, whereas the cellular nitrogenous components decreased significantly. Consequently, the protein/glucan ratio decreased to <0.1. This study indicates that β-1,3-glucan functions both as a short-term diurnal reserve and a long-term stockpile reserve.

Field investigations by other workers suggest that glucan plays a very active role in the dynamics of natural diatom populations, and the protein/glucan ratio has been used as a sensitive parameter for nutrient status. The glucan dynamics may be involved in physiological control of buoyancy. Glucan accumulation by nutrient-deplete cells causes increased cellular density and sinking below the nutricline. Upon nutrient replenishment and mobilization of glucan, the cells rise toward the surface of the water column, thereby transporting deep nutrients to the euphotic zone. β-1,3-Glucan also seems to play an important role in the development of resting stages in diatoms.

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Van, der Merwe Laurianne. "UDP-glucose: β-(1-3)-glucan (paramylon) synthase from Euglena gracilis". Thesis, Stellenbosch : University of Stellenbosch, 2007. http://hdl.handle.net/10019.1/1560.

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Thesis (MSc (Plant Biotechnology))--University of Stellenbosch, 2007.
The photosynthetic protist Euglena gracilis synthesizes a storage carbohydrate named paramylon, a glucan consisting only of β-(1-3)-glycosidic linkages. The enzyme that produces paramylon is a glycosyltransferase commonly known as paramylon synthase (EC 2.4.1.34; UDP-glucose: 1,3-β-D-glucan 3-β-D-glucosyl transferase). This enzyme uses UDP-glucose as its main substrate. In 2001, Bäumer et al. isolated and partially purified paramylon synthase, but never presented any sequence information. Hence, the main aim of this project was to isolate and characterize the gene(s) coding for the paramylon synthase. Different approaches were taken in order to isolate and characterize the gene(s). In the first part of the study molecular techniques were used to try and identify the gene. The two methods used were library screening and PCR amplification. Different libraries were screened using either functional staining or an affinity probe. The second method concentrated on the use of degenerate oligonucleotides, based on the amino acid sequences of conserved regions from known β-(1-3)-glucan synthase genes from various organisms, to PCR amplify the gene sequence from Euglena. These approaches were not successful in the isolation of the gene(s). In the second part of the study protein purification techniques were used in an attempt to obtain de novo protein sequence from the purified paramylon synthase enzyme. Several protein purification techniques were tried with the most successful being preparative ultra centrifugation followed either by sucrose density centrifugation or product entrapment (a type of affinity purification). These resulted in partial purification of the paramylon synthase protein. The partially purified proteins were separated using polyacrylamide gel electrophoresis, and the polypeptides able to bind the precursor, UDP-glucose, were identified using a radiolabeled isotope of UDP-glucose. These polypeptides were subjected to LC-MS-MS in order to obtain sequence information from them. One tryptic fragment showed high homology to β-(1,3)-glucan synthase genes from different yeasts.

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Marins, de Sa Roberta. "Study of β-glucan breakdown and endosperm modification during malting of barley". Thesis, Heriot-Watt University, 2004. http://hdl.handle.net/10399/322.

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Hancock, Robert D. "Exo-β-(1→3)-glucan (curdlan) biosynthesis by Agrobacterium sp. ATCC 31749". Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/14981.

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The present study describes physiological conditions which promote curdlan synthesis, the effect of metabolic inhibitors on production and the nature of the product of Agrobacterium sp. ATCC 31749, a laboratory derivative of a strain originally isolated from soil. Nitrogen depletion in the medium was essential for production, and depletion of sulphur or phosphorus in batch culture did not promote curdlan synthesis. Similarly, initiation of curdlan production was observed when bacteria were transferred to nitrogen free medium but not media free of sulphur or phosphorus. A model of the mechanism of nitrogen dependent control is presented. Agrobacterium sp. ATCC 31749 grew well on a number of monosaccharides and lactose, moderately well on succinate and poorly on glycerol. Good curdlan production was observed from mannose, glucose and galactose with a reasonable curdlan yield obtained from sucrose. Curdlan yields when lactose, maltose or glycerol were supplied were poor and no curdlan was obtained from culture on succinate. The effects of other physiological conditions were examined. Arsenate inhibited neither initiation nor continuation of curdlan biosynthesis when added to the medium in concentrations up to 10mM. 5mM sodium azide inhibited curdlan production but not glucose uptake. A similar effect was observed when the ionophore tetracaine (1mgml^-1) was added to the medium. EDTA inhibited curdlan production and glucose uptake whilst EGTA inhibited neither. Chloramphenicol inhibited curdlan production as did rifampicin. Analysis of the kinetics and degradation products of enzyme hydrolysis revealed a similarity between neutralised gels and gels formed by low temperature heating. Results obtained with native curdlan or curdlan preparations obtained by boiling aqueous suspensions were similar. The implications or these results on curdlan biosynthesis are discussed.

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Cox, Chasity Marie. "The effects of dietary β-glucan supplementation on performance and immune response of broiler chicks during an Eimeria challenge". Thesis, Virginia Tech, 2009. http://hdl.handle.net/10919/46327.

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Escalating consumer concerns have placed the poultry industry under mounting pressure to reduce the use of chemotherapeutic agents as feed additives. One possible alternative receiving increased attention is the use of immunomodulators such as β-glucan. A pilot study evaluated the effects of a yeast derived β-glucan (Auxoferm YGT) on growth performance and immune response of broiler chickens. Day-old chicks were fed a diet containing 0, 0.02, or 0.1% yeast β-glucan. On days 7 and 14 post-hatch, body weight and relative immune organ weights were measured, peripheral blood was collected to determine heterophil to lymphocyte (H:L) ratios, and small intestinal sections were sampled to evaluate relative gene expression. The addition of β-glucan had no influence on growth. Dietary β-glucan supplementation modulated the expression of interleukin (IL)-8, IL-18, interferon (IFN)-γ and inducible nitric oxide synthase (iNOS) in the small intestine. A subsequent study was conducted to investigate the effects of dietary β-glucan on broiler chick (1440 birds) performance and immune response during a mixed Eimeria infection (day 8 of age). Measurements were taken and samples collected on days 4, 7, 10, 14 and 21 post-hatch. The results from this study show that β-glucan supplementation did not negatively impact performance. The addition of β-glucan to the diet resulted in reduced gross lesion severity and increased H:L ratios. The gene expression results suggest that β-glucans are capable of skewing the host immune response toward aTh1 mediated response and consequently down-regulating the Th2 mediated response.
Master of Science

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Konishi, Teruko. "THE EXPRESSION OF SUCROSE SYNTHASE AND ITS ROLE IN PLANT β-GLUCAN SYNTHESIS". Kyoto University, 2002. http://hdl.handle.net/2433/149898.

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Kyoto University (京都大学)
0048
新制・課程博士
博士(農学)
甲第9606号
農博第1234号
新制||農||841(附属図書館)
学位論文||H14||N3638(農学部図書室)
UT51-2002-G364
京都大学大学院農学研究科応用生命科学専攻
(主査)教授酒井富久美, 教授關谷次郎, 教授島田幹夫
学位規則第4条第1項該当

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Tada, Toshio. "Structure and Viscoelastic Properties of Microbial β-1, 3-Glucan Solutions and Gels". Kyoto University, 1998. http://hdl.handle.net/2433/182309.

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Частини книг з теми "(1,3;1,4)-β-glucan"

Dangi, Priya, Nisha Chaudhary, Riya Joshi, and Saranya Prabha. "Beta-glucan (β-glucan)." In Handbook of Cereals, Pulses, Roots, and Tubers, 133–48. Boca Raton: CRC Press, 2021. http://dx.doi.org/10.1201/9781003155508-9.

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Doly, Stéphane, Silvina Laura Diaz, Arnauld Belmer, Anne Roumier, Luc Maroteaux, Carine Becamel, Philippe Marin, and Joël Bockaert. "β-Glucan Receptor." In Encyclopedia of Signaling Molecules, 19. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100000.

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Yoshida, Minoru. "β-D-Glucan Testing." In Aspergillosis: From Diagnosis to Prevention, 125–33. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2408-4_8.

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Wasserman, B. P., T. L. Mason, D. J. Frost, S. M. Read, R. M. Slay, and A. E. Watada. "(1,3)-β-Glucan Synthase." In ACS Symposium Series, 248–56. Washington, DC: American Chemical Society, 1989. http://dx.doi.org/10.1021/bk-1989-0399.ch018.

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Venkatachalam, Geetha, Sathyanarayana Gummadi, and Mukesh Doble. "Mechanism of Cyclic β-Glucan Production." In SpringerBriefs in Microbiology, 71–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-32995-1_7.

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Fèvre, M., V. Girard, and P. Nodet. "Cellulose and β-Glucan Synthesis in Saprolegnia." In Biochemistry of Cell Walls and Membranes in Fungi, 97–107. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74215-6_7.

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Venkatachalam, Geetha, Sathyanarayana Gummadi, and Mukesh Doble. "Extraction and Purification of Cyclic β-Glucan." In SpringerBriefs in Microbiology, 63–69. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-32995-1_6.

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Prajapati, Vimalkumar, Radhika Patel, and Kamlesh Patel. "Microbial β-Glucan: Production, Extraction, and Characterization." In Springer Protocols Handbooks, 115–22. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2601-6_14.

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Mishra, Neha. "Cereal β Glucan as a Functional Ingredient." In Innovations in Food Technology, 109–22. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-6121-4_8.

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Mizuno, Masashi. "Immunomodulatory Activities of β-Glucan in Mushroom." In ACS Symposium Series, 399–407. Washington, DC: American Chemical Society, 2008. http://dx.doi.org/10.1021/bk-2008-0993.ch034.

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Тези доповідей конференцій з теми "(1,3;1,4)-β-glucan"

Gribkova, I. N., та V. I. Kozlov. "β-GLUCAN EFFECT ON BEER QUALITY". У Aktualnye voprosy industrii napitkov. Izdatelstvo i tipografiya "Kniga-memuar", 2018. http://dx.doi.org/10.21323/978-5-6041190-3-7-2018-2-42-44.

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Tercelj, Marjeta, Barbara Salobir та Ragnar Rylander. "β-glucan in lymph nodes in sarcoidosis patients". У ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa828.

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Ibrahim, M. N. G., та I. S. Selezneva. "β-glucan extract from oat bran and its industrial importance". У 3RD ELECTRONIC AND GREEN MATERIALS INTERNATIONAL CONFERENCE 2017 (EGM 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.5002997.

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Aboushanab, S. A. S., D. V. Vyrova, I. S. Selezneva та M. N. G. Ibrahim. "The potential use of β-Glucan in the industry, medicine and cosmetics". У PHYSICS, TECHNOLOGIES AND INNOVATION (PTI-2019): Proceedings of the VI International Young Researchers’ Conference. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5134349.

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Iossifova, Y., T. Reponen, D. Bernstein, H. Kalra, A. Masino та K. Hershey. "29. (1–3)-Β-D-glucan as a Surrogate for Mold Exposure". У AIHce 2005. AIHA, 2005. http://dx.doi.org/10.3320/1.2758765.

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Chamidah, A., Hardoko та A. A. Prihanto. "Antibacterial activities of β-glucan (laminaran) against gram-negative and gram-positive bacteria". У 2ND INTERNATIONAL CONFERENCE ON COMPOSITE MATERIALS AND MATERIAL ENGINEERING (ICCMME 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.4983422.

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Sooriyaarachchi, Sanjeewani, Adrian Suárez Covarrubias, Wimal Ubhayasekera, Frederick O. Asiegbu та Sherry L. Mowbray. "A new class of Scots pine antimicrobial proteins, which act by binding β-glucan". У Proceedings of the International Conference on Antimicrobial Research (ICAR2010). WORLD SCIENTIFIC, 2011. http://dx.doi.org/10.1142/9789814354868_0001.

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Singhvi, D. G., S. M. Nouraie, M. Finkelman, Y. Zhang, Y. Zhang, A. Morris, F. C. Sciurba та J. M. Bon. "Relationship Between Plasma 1→3-β-D-Glucan Levels and Pulmonary Function in COPD". У American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2859.

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Kadir, Zaiton Abdul, Fauzi Daud, Azhar Mohamad, Sahidan Senafi та Ferlynda Fazleen Jamaludin. "Optimization of β-glucan synthase gene primers for molecular DNA fingerprinting in Pleurotus pulmonarious". У THE 2015 UKM FST POSTGRADUATE COLLOQUIUM: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. AIP Publishing LLC, 2015. http://dx.doi.org/10.1063/1.4931252.

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Fajriah, Sofa, Ellya Sinurat, Megawati Megawati, Akhmad Darmawan, Lia Meilawati, Sri Handayani та Hariyanti Hariyanti. "Identification of β-1,3-glucan and α-glucosidase inhibitory activity from seagrape Caulerpa lentillifera extracts". У SolarPACES 2017: International Conference on Concentrating Solar Power and Chemical Energy Systems. Author(s), 2018. http://dx.doi.org/10.1063/1.5064312.

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Звіти організацій з теми "(1,3;1,4)-β-glucan"

Schwartz, Bertha, Vaclav Vetvicka, Ofer Danai, and Yitzhak Hadar. Increasing the value of mushrooms as functional foods: induction of alpha and beta glucan content via novel cultivation methods. United States Department of Agriculture, January 2015. http://dx.doi.org/10.32747/2015.7600033.bard.

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Анотація:

During the granting period, we performed the following projects: Firstly, we differentially measured glucan content in several pleurotus mushroom strains. Mushroom polysaccharides are edible polymers that have numerous reported biological functions; the most common effects are attributed to β-glucans. In recent years, it became apparent that the less abundant α-glucans also possess potent effects in various health conditions. In our first study, we explored several Pleurotus species for their total, β and α-glucan content. Pleurotuseryngii was found to have the highest total glucan concentrations and the highest α-glucans proportion. We also found that the stalks (stipe) of the fruit body contained higher glucan content then the caps (pileus). Since mushrooms respond markedly to changes in environmental and growth conditions, we developed cultivation methods aiming to increase the levels of α and β-glucans. Using olive mill solid waste (OMSW) from three-phase olive mills in the cultivation substrate. We were able to enrich the levels mainly of α-glucans. Maximal total glucan concentrations were enhanced up to twice when the growth substrate contained 80% of OMSW compared to no OMSW. Taking together this study demonstrate that Pleurotuseryngii can serve as a potential rich source of glucans for nutritional and medicinal applications and that glucan content in mushroom fruiting bodies can be further enriched by applying OMSW into the cultivation substrate. We then compared the immune-modulating activity of glucans extracted from P. ostreatus and P. eryngii on phagocytosis of peripheral blood neutrophils, and superoxide release from HL-60 cells. The results suggest that the anti-inflammatory properties of these glucans are partially mediated through modulation of neutrophileffector functions (P. eryngiiwas more effective). Additionally, both glucans dose-dependently competed for the anti-Dectin-1 and anti-CR3 antibody binding. We then tested the putative anti-inflammatory effects of the extracted glucans in inflammatory bowel disease (IBD) using the dextran sulfate sodium (DSS)–induced model in mice. The clinical symptoms of IBD were efficiently relieved by the treatment with two different doses of the glucan from both fungi. Glucan fractions, from either P. ostreatus or P. eryngii, markedly prevented TNF-α mediated inflammation in the DSS–induced inflamed intestine. These results suggest that there are variations in glucan preparations from different fungi in their anti-inflammatory ability. In our next study, we tested the effect of glucans on lipopolysaccharide (LPS)-induced production of TNF-α. We demonstrated that glucan extracts are more effective than mill mushroom preparations. Additionally, the effectiveness of stalk-derived glucans were slightly more pronounced than of caps. Cap and stalk glucans from mill or isolated glucan competed dose-dependently with anti-Dectin-and anti-CR-3 antibodies, indicating that they contain β-glucans recognized by these receptors. Using the dextran sulfate sodium (DSS)-inflammatory bowel disease mice model, intestinal inflammatory response to the mill preparations was measured and compared to extracted glucan fractions from caps and stalks. We found that mill and glucan extracts were very effective in downregulatingIFN-γ and MIP-2 levels and that stalk-derived preparations were more effective than from caps. The tested glucans were equally effective in regulating the number of CD14/CD16 monocytes and upregulating the levels of fecal-released IgA to almost normal levels. In conclusion, the most effective glucans in ameliorating some IBD-inflammatory associated symptoms induced by DSS treatment in mice were glucan extracts prepared from the stalk of P. eryngii. These spatial distinctions may be helpful in selecting more effective specific anti-inflammatory mushrooms-derived glucans. We additionally tested the effect of glucans on lipopolysaccharide-induced production of TNF-α, which demonstrated stalk-derived glucans were more effective than of caps-derived glucans. Isolated glucans competed with anti-Dectin-1 and anti-CR3 antibodies, indicating that they contain β-glucans recognized by these receptors. In conclusion, the most effective glucans in ameliorating IBD-associated symptoms induced by DSS treatment in mice were glucan extracts prepared from the stalk of P. eryngii grown at higher concentrations of OMSW. We conclude that these stress-induced growing conditions may be helpful in selecting more effective glucans derived from edible mushrooms. Based on the findings that we could enhance glucan content in Pleurotuseryngii following cultivation of the mushrooms on a substrate containing different concentrations of olive mill solid waste (OMSW) and that these changes are directly related to the content of OMSW in the growing substrate we tested the extracted glucans in several models. Using dextran sulfate sodium (DSS)–inflammatory bowel disease (IBD) mice model, we measured the colonic inflammatory response to the different glucan preparations. We found that the histology damaging score (HDS) resulting from DSS treatment reach a value of 11.8 ± 2.3 were efficiently downregulated by treatment with the fungal extracted glucans, glucans extracted from stalks cultivated at 20% OMSWdownregulated to a HDS value of 6.4 ± 0.5 and at 80% OMSW showed the strongest effects (5.5 ± 0.6). Similar downregulatory effects were obtained for expression of various intestinal cytokines. All tested glucans were equally effective in regulating the number of CD14/CD16 monocytes from 18.2 ± 2.7 % for DSS to 6.4 ± 2.0 for DSS +glucans extracted from stalks cultivated at 50% OMSW. We finally tested glucans extracted from Pleurotuseryngii grown on a substrate containing increasing concentrations of olive mill solid waste (OMSW) contain greater glucan concentrations as a function of OMSW content. Treatment of rat Intestinal epithelial cells (IEC-6) transiently transfected with Nf-κB fused to luciferase demonstrated that glucans extracted from P. eryngii stalks grown on 80% OMSWdownregulatedTNF-α activation. Glucans from mushrooms grown on 80% OMSW exerted the most significant reducing activity of nitric oxide production in lipopolysaccharide (LPS) treated J774A.1 murine macrophages. The isolated glucans were tested in vivo using the Dextran Sodium Sulfate (DSS) induced colitis in C57Bl/6 mice and found to reduce the histology damaging score resulting from DSS treatment. Expression of various intestinal cytokines were efficiently downregulated by treatment with the fungal extracted glucans. We conclude that the stress-induced growing conditions exerted by OMSW induces production of more effective anti-inflammatory glucans in P. eryngii stalks.

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