Добірка наукової літератури з теми "028(043)"

Dijelaskan riset menganalisa harga, kualitas produk, kualitas layanan serta lokasi terhadap keputusan pembelian lapis kukus pahlawan. Riset ini memakai pendekatakan kuantitatif deskriptif, telah diperoleh hasil thitung 2,564 serta Sig. sebesar ,012 sehingga ,012 < ,05. kualitas produk 2,055 sig. ,043<,05. kualitas layanan 2,216 serta Sig. ,036. lokasi 2,231 serta Sig. ,028. nilai f-hitung serta diketahui F hitung 5,972 serta sig. ,000 < 0,05. Disimpulkan pengujian secara terpisah serta bersamaan terbukti adanya pengaruh variabel bebas terhadap variabel terikat.

eSports gaming requires quick and accurate reactions in response to complex visual stimuli for optimal performance. The purpose of this study was to examine the relationship between components of physical fitness and reaction time (RT) in eSports gamers. 27 eSports gamers participated. Visit 1 included physical fitness assessments. Visit 2 included a familiarization with the Stroop Task. During Visit 3, subjects completed the Stroop Task again; data from this visit was used for analyses. For congruent, incongruent and control trials, an inverse efficiency score (IES) was calculated. Pearson correlations were used to determine the relationship between components of physical fitness and mean RT. There was a significant correlation between mean RT and cardiorespiratory fitness (r=-.338, p=.043). IES was significantly related to cardiorespiratory fitness in incongruent (r=-.373, p=.028) and control (r=-.333, p=.045) trials. Results suggest that increased cardiorespiratory fitness can improve reaction time and also induce greater efficiency.

Abstract A growing number of in vitro studies suggest that recombinant human stem cell factor (SCF) is capable of augmenting the proliferative capacity of human hematopoietic progenitor cells (HPC) and stem cells (HSC). We further evaluated this biologic effect by analyzing the response of bone marrow (BM) HPCs and HSCs to the administration of SCF in eight patients with locally advanced or metastatic breast cancer who were enrolled in an ongoing phase I study. SCF was administered for 14 days by daily subcutaneous injection at dosages of 10, 25, or 50 micrograms/kg/d. BM CD34+ HLA-DR+ and CD34+ HLA-DR- CD15- cells, previously shown by our laboratory to be enriched for various classes of differentiated and primitive HPCs, respectively, were quantitated in BM samples on day 0 (pretreatment) and day 15 (posttreatment). These CD34+ HLA-DR+ and CD34+ HLA-DR- CD15- cells were then isolated by cell- sorting and assayed for several classes of HPCs, including the high-- proliferative potential colony-forming cell (HPP-CFC), the burst- forming unit--megakaryocyte (BFU-MK), and the long-term BM culture-- initiating cell (LTBMC-IC). SCF administration resulted in a 3.3-fold (range, 1.4- to 18.8-fold; P = .018) increase in the absolute numbers of CD34+ cells, a 3.7-fold (range, 1.2- to 8.2-fold; P = .028) increase in the absolute numbers of CD34+ HLA-DR+ cells, and a 2.4-fold (range, 1.1- to 29.3-fold; P = .010) increase in the absolute numbers of CD34+ HLA-DR- CD15- cells. Following the infusion of SCF, a statistically significant increase in the absolute numbers of HPP-CFC (P = .018), BFU- MK (P = .046), CFU-granulocyte, erythrocyte, monocyte, megakaryocyte (CFU-GEMM: P = .043), BFU-erythrocyte (BFU-E; P = .043), CFU- granulocyte, macrophage (CFU-GM; P = .045), and CFU-megakaryocyte (CFU- MK; P = .028) per milliliter of marrow was observed. Stromal cell-free LTBMCs supplemented with SCF and interleukin-3 (IL-3), initiated with CD34+ HLA-DR- CD15- cells obtained on day 0, produced viable cells for 9.6 weeks, compared with 11.5 weeks for LTBMCs initiated with CD34+ HLA- DR- CD15- cells obtained on day 15. Cumulative cellular production by LTBMCs initiated with day 15 CD34+ HLA-DR- CD15- cells was statistically greater than that by day 0 LTBMCs (P = .031). These same cultures produced CFU-GM for 6.3 weeks (day 0) versus 9 weeks (day 15).(ABSTRACT TRUNCATED AT 400 WORDS)

A growing number of in vitro studies suggest that recombinant human stem cell factor (SCF) is capable of augmenting the proliferative capacity of human hematopoietic progenitor cells (HPC) and stem cells (HSC). We further evaluated this biologic effect by analyzing the response of bone marrow (BM) HPCs and HSCs to the administration of SCF in eight patients with locally advanced or metastatic breast cancer who were enrolled in an ongoing phase I study. SCF was administered for 14 days by daily subcutaneous injection at dosages of 10, 25, or 50 micrograms/kg/d. BM CD34+ HLA-DR+ and CD34+ HLA-DR- CD15- cells, previously shown by our laboratory to be enriched for various classes of differentiated and primitive HPCs, respectively, were quantitated in BM samples on day 0 (pretreatment) and day 15 (posttreatment). These CD34+ HLA-DR+ and CD34+ HLA-DR- CD15- cells were then isolated by cell- sorting and assayed for several classes of HPCs, including the high-- proliferative potential colony-forming cell (HPP-CFC), the burst- forming unit--megakaryocyte (BFU-MK), and the long-term BM culture-- initiating cell (LTBMC-IC). SCF administration resulted in a 3.3-fold (range, 1.4- to 18.8-fold; P = .018) increase in the absolute numbers of CD34+ cells, a 3.7-fold (range, 1.2- to 8.2-fold; P = .028) increase in the absolute numbers of CD34+ HLA-DR+ cells, and a 2.4-fold (range, 1.1- to 29.3-fold; P = .010) increase in the absolute numbers of CD34+ HLA-DR- CD15- cells. Following the infusion of SCF, a statistically significant increase in the absolute numbers of HPP-CFC (P = .018), BFU- MK (P = .046), CFU-granulocyte, erythrocyte, monocyte, megakaryocyte (CFU-GEMM: P = .043), BFU-erythrocyte (BFU-E; P = .043), CFU- granulocyte, macrophage (CFU-GM; P = .045), and CFU-megakaryocyte (CFU- MK; P = .028) per milliliter of marrow was observed. Stromal cell-free LTBMCs supplemented with SCF and interleukin-3 (IL-3), initiated with CD34+ HLA-DR- CD15- cells obtained on day 0, produced viable cells for 9.6 weeks, compared with 11.5 weeks for LTBMCs initiated with CD34+ HLA- DR- CD15- cells obtained on day 15. Cumulative cellular production by LTBMCs initiated with day 15 CD34+ HLA-DR- CD15- cells was statistically greater than that by day 0 LTBMCs (P = .031). These same cultures produced CFU-GM for 6.3 weeks (day 0) versus 9 weeks (day 15).(ABSTRACT TRUNCATED AT 400 WORDS)

Adiponectin has been associated with insulin resistance and type 2 diabetes mellitus and possibly fetal growth. Our aim was to assess the association between the single nucleotide polymorphisms (SNPs) of the adiponectin gene (ADIPOQ) and the birth sizes. We investigated four SNPs of ADIPOQ (rs182052, rs2241766, rs1501299, and rs266729) and birth height and weight in 237 healthy full-term neonates. The neonates with the rs182052 G allele had a greater birth weight (p = .043 in the dominant model) and a higher ponderal index (p = .028 in the additive model). The rs2241766 G allele was associated with a greater birth weight (p = .016 in the recessive model). In a logistic regression analysis, the homozygotes for the rs182052 G allele and those for the rs2241766 G allele showed a significant association with a greater birth weight above 90 percentile (OR 2.75, 95% CI 1.13–6.70 and OR 5.15, 95% CI 1.66–15.99, respectively). In conclusion, we found an association between rs182052 and rs2241766 and birth weight and ponderal index among healthy neonates and suggested that adiponectin might have some roles in fetal growth.

PURPOSE: The rarity and heterogeneity of pediatric nonrhabdomyosarcoma soft tissue sarcoma (NRSTS) has precluded meaningful analysis of prognostic factors associated with surgically resected disease. To define a population of patients at high risk of treatment failure who might benefit from adjuvant therapies, we evaluated the relationship between various clinicopathologic factors and clinical outcome of children and adolescents with resected NRSTS over a 27-year period at our institution. PATIENTS AND METHODS: We analyzed the records of 121 consecutive patients with NRSTS who underwent surgical resection between August 1969 and December 1996. Demographic data, tumor characteristics, treatment, and outcomes were recorded. Univariate and multivariate analyses of prognostic factors for survival, event-free survival (EFS), and local and distant recurrence were performed. RESULTS: At a median follow-up of 9.2 years, 5-year survival and EFS rates for the entire cohort were 89% ± 3% and 77% ± 4%, respectively. In univariate models, positive surgical margins (P = .004), tumor size ≥ 5 cm (P < .001), invasiveness (P = .002), high grade (P = .028), and intra-abdominal primary tumor site (P = .055) adversely affected EFS. All of these factors except invasiveness remained prognostic of EFS and survival in multivariate models. Positive surgical margins (P = .003), intra-abdominal primary tumor site (P = .028), and the omission of radiation therapy (P = .043) predicted local recurrence, whereas tumor size ≥ 5 cm (P < .001), invasiveness (P < .001), and high grade (P = .004) predicted distant recurrence. CONCLUSION: In this largest single-institution analysis of pediatric patients with surgically resected NRSTS, we identified clinicopathologic features predictive of poor outcome. These variables should be prospectively evaluated as risk-adapted therapies are developed.

SUMMARYThere is some suggestion that infection with pandemic influenza may increase long-term mortality risks. Therefore we aimed to determine if exposure to a severe outbreak of pandemic influenza on a troopship in 1918 impacted on lifespan in the survivors. The troopship with the outbreak cohort had 1107 personnel and the comparison cohort was from two contemporaneous troopships (1108 randomly selected personnel). Data were collected from online individual military files. The main finding was that there was no statistically significant difference in the lifespan of the outbreak cohort and the comparison cohort (means of 71·5 and 71·0 years, respectively). Indeed, the outbreak cohort was actually more likely to survive into the period from 1950 onwards (P = 0·036) and to participate in the Second World War (P = 0·043). There were no significant differences between the cohorts in terms of occupational class, but the comparison cohort had a higher proportion of rural occupations (33·3% vs. 27·0%, P < 0·001) and was very slightly older in mid-1918 (27·8 vs. 27·2 years, P = 0·028). In conclusion, this study found no support for the hypothesis that exposure to the 1918 influenza pandemic adversely impacted on the lifespan in the survivors, at least in this male and military-age population.

Iron depletion, with or without anemia, may have a negative effect on physical and mental performance. Even with current recognition of the problem, its incidence among athletes remains high. Most studies describe iron status in endurance athletes. This study examined the prevalence of iron depletion and anemia among male and female top-level basketball players. Adolescents and adults (N = 103) from 8 national basketball teams were screened for anemia and iron stores status, which included a complete blood count and levels of plasma ferritin, transferrin, and serum iron. Iron depletion, defined by a ferritin level below 20 μg/L, was found among 22% of study participants (15% in males vs. 35% in females, p = .019). Anemia was found among 25% of athletes (18% in males vs. 38% in females, p = .028). Iron deficiency anemia, defined by the presence of anemia, ferritin levels below 12 μg/L, and transferrin saturation below 16%, was found among 7% of players (3% in males vs. 14% in females, p = .043). In summary, a high prevalence of iron depletion, anemia, and iron deficiency anemia was found among basketball players of both genders. We recommend screening ballgame players for blood count and iron store status, and providing nutritional counseling and iron supplementation when necessary.

Interprofessional education (IPE) is a critical area needed to improve the quality of healthcare. Stereotypes of other disciplines persist by healthcare workers, limiting the ability to work as a team. Knowledge of roles of healthcare professions is a key competency of IPE. An online, 12-week course was developed to introduce students to the interdisciplinary nature of healthcare through case study models. Through built-in links, students explore medical terminology, diagnostic testing, pathophysiology, treatment, and health professionals who work as a team to diagnose and treat the patient. A 24-question survey was administered to a convenience sample of 582 high school students. Results of paired-samples t-tests showed significant increases pre-training to post-training in: 1) knowledge of the different roles of health professionals, (n = 338, M = .71, SEM = .01) to post-training (M = .82, SEM = .01), t(337) = 11.08, p<.001, pη2 = .203, 2) and self-reported knowledge of roles of different health professions, pre-training (n = 338, M = 2.73, SEM = .30) to post-training (M = 3.60, SEM = .039), t(337) = 20.02, p < .001, pη2 = .543. Interestingly, students’ likelihood in a career in healthcare professions decreased significantly pre-training (n = 338, M = 4.30, SEM = .043) to post-training (M = 4.20, SEM = .06), t(337) = 2.21, p = .028, pη2 = .016. Introducing knowledge of health professions to this population may be critical in avoiding stereotypes before a student enters a chosen career path, increasing the likelihood of participation in interdisciplinary teams.

Dissertação de Mestrado em Ensino do 1º e 2º Ciclos do Ensino Básico
A leitura estimula uma série de potencialidades intrínsecas à Língua Portuguesa e que se estendem igualmente ao currículo escolar, dado o caráter transversal que lhe é conferido. Com base nos estudos que proliferam e dão conta da relação irrevogável entre a leitura e o sucesso escolar, procuramos direcionar os estudos para a influência desta competência na resolução de problemas matemáticos. A relação estabelecida entre os domínios referidos é assegurada ao longo deste trabalho por uma revisão bibliográfica suficientemente competente, mas fundamentalmente por um estudo empírico realizado no decorrer da Prática de Ensino Supervisionado no 1.º e 2.º Ciclos do Ensino Básico. Serão apresentados resultados conseguidos através dos inquéritos por questionário, cuja amostra é representada pelos alunos das turmas 4.ºJ 8 e 5.ºD. A análise minuciosa dos dados permitirá estabelecer individualmente a relação entre a competência leitora e a aptidão para a resolução de problemas, podendo servir como um bom indicador para futuras investigações. Desta forma, esta dissertação exigiu uma pesquisa constante e uma reflexão ponderada dos resultados obtidos para efetivar os pressupostos levantados em volta desta problemática.
Reading stimulates a series of intrinsic potential to portuguese and extends also to the school curriculum, given the cross-cutting character given to it. Based on studies which proliferate and give account of irrevocable relationship between reading and school success, seek direct studies to the influence of this competence in solving problems. The relationship established between the domains referred to is backed up by a literature reviews sufficiently competent and essentially by an empirical study carried out in the course of Supervised Teaching practice on the first and second Cycles of basic education. The results achieved will be presented through surveys, whose sample is represented by students of class 4. ºJ8 e 5. ºD. The detailed analysis of the data will make it possible to establish the individual relationship between reader and the competence aptitude for problem solving, and can serve as a good indicator for future investigations. This work required a constant research and a careful consideration of the results obtained to effect the assumptions raised around this issue.

Dissertação de Mestrado em Ciências da Educação, Especialização em Animação Sociocultural
A leitura reveste-se de uma importância crucial na vida do homem. O hábito de ler pode e deve ser estimulado em todas as faixas etárias, preferencialmente desde tenra idade, para que a criança assimile que ler é algo importante e prazeroso, contribuindo para que venha a tornar-se num adulto culto, ativo e astuto. Promover a leitura é uma das funções da Animação Sociocultural, motivando o indivíduo a ler através de atividades realizadas no âmbito da promoção da leitura. Neste sentido, o animador desempenha um papel fundamental na medida em que tem a árdua tarefa de motivar o indivíduo para a sua prática, tarefa esta que não se revela nada fácil perante o enorme leque de solicitações que a sociedade atual oferece. Para melhor alcançar o seu objetivo, a Biblioteca e o animador tem ao seu dispor uma panóplia de técnicas de animação que podem facilitar o seu trabalho, tornando a prática da leitura mais interessante e aliciante. A presente investigação consiste num estudo de caso ao longo do qual se constata a existência de reduzidos hábitos de leitura entre a população de um concelho do interior. Os resultados permitiram concluir também a existência de frequências médias baixas de incentivo à leitura. Constatamos, ainda, que os participantes nas atividades de promoção da leitura realizadas na Biblioteca, atribuem níveis altos de importância a todas elas e que sentem que ocorreram mudanças nos seus hábitos de leitura após a participação nas mesmas, existindo um incremento nas suas práticas de leitura. A maioria crê ser importante que existam atividades entre a terceira idade e as crianças/jovens e que estas ajudaram a mudar a visão que possuíam da outra geração, contribuindo assim para aproximar gerações.
Reading is believed to be of crucial importance in the human life. The reading habit can and should be stimulated in all age groups, preferably from an early age, so that the child assimilates that reading is something important and pleasurable, contributing to the child’s growth in becoming an educated, active and astute adult. Promoting reading is one of the Sociocultural Animation’s functions, motivating the individual to read through activities performed in the reading promotion. In this sense, the impeller has a fundamental role since he has the arduous task of motivating the individual for its practice, revealing that the task is not easy towards the enormous range of solicitations that the modern society has to offer. In order to best achieve his goal, the impeller has at his disposal a wide range of animation techniques that may help making the job less arduous, turning the practice of reading even more interesting and attractive. Throughout our investigation we carried out a study case in which we found the existence of reduced reading habits amongst the population. The results also allowed us to conclude that there are medium-lower frequencies of reading incentives. We have also found out that the participants in the reading promotion activities conducted in the library, attribute high levels of importance to all the activities and that these participants feel that there have been changes in their reading habits, after their participation in the activities, and that there was an increase in their reading pattern. The majority believes it is important that there are activities between the elderly and children/young people and that these activities have helped change their view about the other generation and have also contributed to bring generations closer.