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1

Yang, Liping, Xin Wan, Runyang Zhou e Yingdan Yuan. "The Composition and Function of the Rhizosphere Bacterial Community of Paeonia lactiflora Varies with the Cultivar". Biology 12, n.º 11 (24 de outubro de 2023): 1363. http://dx.doi.org/10.3390/biology12111363.

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The composition and diversity of the rhizosphere microbial community maintain the stability of the root microclimate, and several studies have focused on this aspect of rhizosphere microorganisms. However, how these communities vary with cultivars of a species is not completely understood. Paeonia lactiflora—a perennial herb species of the family Paeoniaceae—includes a wide variety of cultivars, with rich rhizosphere microbial resources. Hence, we studied the differences in rhizosphere bacterial communities associated with eight P. lactiflora cultivars. We noted that Actinobacteria, Proteobacteria, Acidobacteria, Bacteroidetes, Firmicutes, Verrucomicrobia, Planctomycetes and Chloroflexi were the dominant phyla associated with the cultivars. The composition of rhizosphere bacterial community of different cultivars was highly similar at taxonomic levels, but there were slightly differences in the relative abundance. LEfSe analysis showed that the cultivars “Sheng Tao Hua” and “Zi Lou Xian Jin” exhibited the most biomarkers. Differential ASV analysis revealed the maximum difference in ASV abundance between “Lian Tai” and “Zi Hong Zheng Hui”, as well as between “Sheng Tao Hua” and “Tao Hua Fei Xue”, and the maximum similarity between “Duo Ye Zi” and “Xue Feng”. Co-occurrence network analysis revealed that rhizosphere bacteria in most cultivars maintain homeostasis by cooperation, wherein Actinobacteria and Proteobacteria played a vital role. In addition, microbial resources related to cultivars like bioremediation, organic degradation and resistance to diseases are found. This study revealed the structures of the rhizosphere bacterial communities associated with different cultivars of P. lactiflora and explored their stress resistance potential, which can be used to guide future agricultural practices.
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Jessi Suryani Setiawan, Anindini Winda Amalia e Lim Lia Harumiaty. "Pengaruh Kombinasi Akupunktur dan Formula Bai Zi Yang Xin Tang Pada Klien Insomnia Sindrom Disharmoni Jantung dan Ginjal di Yayasan Sosial Dharma Warga Surabaya". JURNAL FISIOTERAPI DAN ILMU KESEHATAN SISTHANA 5, n.º 2 (26 de julho de 2023): 37–44. http://dx.doi.org/10.55606/jufdikes.v5i2.429.

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Insomnia is one of the most common diseases in modern society, with its characteristics being difficulty sleeping at night or failure to maintain effective sleep after sleep. Conventional treatments for existing insomnia have undesirable effects when used for a long time. Treatment with acupuncture and herbs can be used as an alternative and complementary therapy in the treatment of insomnia. Research purposes to determine the effect of a combination of acupuncture and herbal therapy Bai Zi Yang Xin Tang on client insomnia with heart and kidney disharmony syndrome at Yayasan Dharma Warga Surabaya. Research methods is one group pre-test and post-test design. Respondents in the study amounted to 14 people received acupuncture therapy at point (Feng Chi, An Mian, Bai Hui, Si Shen Cong, Shen Men, Nei Guan, Zu San Li, San Yin Jiao, Tai Xi, Tai Chong) and consumed Bai Zi Yang Xin Tang. The average length of sleep for respondents before therapy was 3.75 ± 0.47 hours and after therapy 6.0 ± 0.65 hours (p < 0.05). The combination of acupuncture and Bai Zi Yang Xin Tang for insomnia with heart and kidney disharmony syndrome can increase the patient's sleep duration after therapy.
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Wu, Jin-an, e li-juan Zhang. "A A elememntary study of East Asian civilization –focusing on th “Gong-ming hui” and “Zi-zheng hui” of confucianism". Institute of Korean Cultural Studies Yeungnam University 74 (30 de abril de 2020): 217–37. http://dx.doi.org/10.15186/ikc.2020.04.30.7.

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Eschenburg, Madeline. "Bentu – Chinese Artists in a Time of Turbulence and Transformation: Suzanne Pagé, Laurence Bossé, Philip Tinari, and Claire Staebler, eds." Contemporaneity: Historical Presence in Visual Culture 6 (30 de novembro de 2017): 93–96. http://dx.doi.org/10.5195/contemp.2017.228.

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Review of Pagé, Suzanne, Laurence Bossé, Philip Tinari, and Claire Staebler, eds. Bentu - Chinese Artists in a Time of Turbulence and Transformation: Cao Fei, Hao Liang, Hu Xiangqian, Liu Chuang, Liu Shiyuan, Liu Wei, Liu Xiaodong, Qiu Zhijie, Tao Hui, Xu Qu, Xu Zhen, Yang Fudong, exh. cat. Paris: Fondation Louis Vuitton, 2016. Texts by Suzanne Pagé, Laurence Bossé, Philip Tinari, Pierre Haski, Lu Minjun, Nikita Yingqian Cai, Sun Dongdong, Claire Staebler, Venus Lau, Sasha Zhao, Robin Peckham, Jerome Sans, Liu Tian, Yang Zi, Zhang Xiyuan, Philip Tinari, and Aimee Lin. 179 pp., 83 color ills., Paperback €35 (978 0 300 22238 8)
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Inafuku, Sonia Hitomi, e Ayne Murata Hayashi. "Acupuncture and chinese herbal medicine in controlling clinical signs of epiphysiolysis in a cat – case report". Clínica Veterinária XXIX, n.º 171 (1 de julho de 2024): 38–47. http://dx.doi.org/10.46958/rcv.2024.xxix.n.171.p.38-47.

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Epiphysiolysis is characterized by lysis in the epiphyseal region of a long bone, which can be caused by a trauma. The present report brings a case of epiphysiolysis, and the treatment using acupuncture and chinese phytotherapy of a young neutered male ragdoll feline, monitored over a period of 11 months. The treatment consisted of eliminating obstruction of the flow of Qi and Xue (Bi bone heat syndrome), toning Jing and toning the Kidney Yin, with the stimulation of the acupuncture points with dry needling, indirect moxibustion and laser acupuncture at the points: VG14, VG20, R3, lumbar Bai Hui, bilateral B23, B54, B60, E36, VB29, bilateral VB30, VB34 and F3 and the oral use of Chinese herbal medicines: Zheng Gu Zi Jin Dan and Qi Bao Mei Ran Dan, with dose adjustment as monitoring and evolution of the case. There has been a significant improvement in the animal’s life quality regarding the pain, with improved mobility and socialization of the animal with other household contacts.
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Lee, Kyeong-Won. "A study of comparison about quantity, lists of the Chinese Radicals between inShuo-Wen, Yu-Pian, Wujing WenZi and Zi-Hui in for regular scripts". Chinese Language Education and Research 12 (30 de novembro de 2010): 147. http://dx.doi.org/10.24285/cler.2010.11.12.147.

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随机电磁涡旋光束的深聚焦特性. "Tight Focusing of Stochastic Electromagnetic Vortex Beams". ACTA PHOTONICA SINICA 40, n.º 11 (2011): 1744–50. http://dx.doi.org/10.3788/gzxb20114011.1744.

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Boldyreva, Elena M. "Hai Zi – Chinese Sergei Yesenin: tanatological poetics and “romance with death”". Vestnik of Kostroma State University 27, n.º 4 (23 de dezembro de 2021): 151–61. http://dx.doi.org/10.34216/1998-0817-2021-27-4-151-161.

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The article considers the work of the Chinese poet Hai Zi (mostly based on works not translated into Russian) as a characteristic example of the spiritual and artistic influence of Sergei Yesenin's work on modern Chinese poetry. The poetic dialogue of Hai Zi and S. Yesenin is considered from the point of view of tanatological poetics, which allows us to present their work as a single meta text, developing various variations of tanatopoetics in order to achieve absolute self-identification by synthesising “self” – death – art. The category of death is considered as the integral basis of the work of S. Yesenin and Hai Zi, which ultimately leads to the realisation of their personal attitude to death as the ontological, epistemological and axiological basis of life and creative work. The article justifies that the “romance with death” of S. Yesenin and Hai Zi is a manifestation of their life-building strategy, consonances in motif and figuration are revealed in the aspect of tanatological poetics, taking into account the different nature of those motifs: the spontaneous-organic feeling of death in S. Yesenin and the tanatological ideology of Hai Zi, based on the synthesis of Western philosophy, Confucianism, Taoism. Particular attention is paid to the consideration of S.Yesenin's poem “The Black Man” and the poem “Spring. Ten Hai Zi” as works that expose the key settings of the poets' tanatological discourse, as well as an analysis of Hai Zi's poem "Life Was Interrupted" as prisms for the reinterpretation of S. Yesenin's life and work within the framework of the tanatological paradigm of "Chinese Yesenin" and the most important act of semiotisation of life and creative work of the Chinese youth, when suicide is positioned as the final statement.
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Tsybikova, Valentina Vladimirovna, e Densema Bulatovna Zhanchipova. "Synthesis of traditional and new in the works of Chinese poet Hai Zi based on the image of grain". Филология: научные исследования, n.º 10 (outubro de 2021): 29–38. http://dx.doi.org/10.7256/2454-0749.2021.10.36635.

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For a long period, the development of Chinese literature is characterized by the continuity of artistic tradition. Chinese poetry of the reform and opening-up era draws profound interest, as it reflects the transformations of modern age and worldview in the Chinese society. This article is dedicated to examination of the traditional images of Chinese literature in the lyrics of prominent Chinese poet of the late XX century Hai Zi (1964&ndash;1989). Since old days, the image of grain resembles the world of nature, fertility, cyclicity of life, symbol of ethno-poetic traditions associated with the motif of hard peasant labor. A remarkable representative of the Chinese poetry of &ldquo;new generation&rdquo;, whose works embody the spiritual pursuits of the era, is the poet Hai Zi. Along with the traditional motifs and images, he integrates the elements of the original concept. This article is first within the Russian Sinology to analyze the system of artistic images in the lyrics of Hai Zi. The conclusion is made that the artistic uniqueness of the works of Chinese poet, this image acquires the individual authorial content &ndash; the bearer of creative energy and active principle, the link between the world of nature and a human.
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Segeun Jeong. "On Jing Shen in the Philosophy of Huai-nan zi". Studies in Philosophy East-West ll, n.º 70 (dezembro de 2013): 121–42. http://dx.doi.org/10.15841/kspew..70.201312.121.

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Синьтун, В. "Hai-Zi’s Poetic Cycle “Esenin, the Poet” as an Important Step in Literary Analysis of Esenin’s Poetic Heritage in China". Иностранные языки в высшей школе, n.º 1(56) (13 de abril de 2021): 24–34. http://dx.doi.org/10.37724/rsu.2021.56.1.003.

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Высшей формой литературного анализа творчества русского поэта Сергея Есенина в Китае стало использование конкретных есенинских символов и образов китайскими писателями в своих произведениях. Первым, кто широко использовал есенинскую образность и проблематику, стал поэт Хай-цзы, который создал широко известный поэтический цикл «Поэт Есенин», тем самым положив начало литературного анализа творчества Есенина в Китае. В статье на материале поэтического цикла Хай-цзы о Есенине выявляется общность поэтического осмысления мира двумя поэтами. The poetic heritage of Sergei Esenin found its highest manifestation in the usage of the great Russian poet’s symbols and imagery in Chinese literary works. The first to resort to Esenin’s imagery and symbolism was the Chinese poet, Hai-zi, who wrote a well-known poetic cyclus “Esenin, the Poet” and thereby laid the corner-stone of Esenin studies in China. The paper examines Hai-zi’s poetic cyclus dedicated to Esenin with the purpose of revealing the kinship of the two poets’ philosophic perception and interpretation of the world. The poems of Hai-zi have been translated by the author of the paper.
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Xie, Chen, Tetsuo Kokubun, Peter J. Houghton e Monique S. J. Simmonds. "Antibacterial activity of the Chinese traditional medicine, Zi Hua Di Ding". Phytotherapy Research 18, n.º 6 (junho de 2004): 497–500. http://dx.doi.org/10.1002/ptr.1497.

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Chan, Jason Yongsheng, Jing Yi Lee, Zi Yi Wan, Abner Herbert Lim, Tun Kiat Ko, Cedric Chuan-Young Ng, Donald Poon et al. "Abstract 6399: Real-world experience of an Asian pan-cancer combined DNA/RNA next generation sequencing (NGS) tissue biopsy assay". Cancer Research 84, n.º 6_Supplement (22 de março de 2024): 6399. http://dx.doi.org/10.1158/1538-7445.am2024-6399.

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Abstract Introduction: Comprehensive molecular profiling with combined DNA-RNA next-generation sequencing (NGS) on tumor tissue is now increasingly being used as standard-of-care for sequence therapy selection to improve cancer survival. Combined DNA-RNA NGS is also considered standard-of-care for central nervous system (CNS) tumor classification. Despite the genetic heterogeneity and diversity of cancers, most commercial combined DNA/RNA NGS assays are validated in Western populations, resulting in knowledge gaps in patient outcomes. We report here for the first time a range of actionable outcomes from a comprehensive DNA/RNA tissue NGS assay designed specifically to probe Asian-prevalent cancers and biomarkers in an international multicenter real-world study in Asia. Methods: 1,002 formalin-fixed paraffin-embedded tissue samples from 995 Asian cancer patients across &gt;70 centers in 7 countries and/or territories underwent real-world DNA/RNA NGS testing in a CAP-accredited CLIA-certified laboratory. Genomic alterations including SNVs, INDELS, gene fusions, CNVs, TMB, and MSI were analyzed using an Asian-centric pan-cancer hybrid-capture NGS panel that comprehensively profiles 572 cancer-related genes and 91 RNA fusion partners (UNITED). Biomarkers were considered actionable if the therapeutic indication in any solid tumor or hematological cancer was FDA-approved, guidelines-recommended, or supported by well-powered phase III clinical trials. Results: 27 cancer types were represented in 1,002 tissue samples, with lung, breast, colorectal, and prostate cancers comprising 45.5% of clinical volume. 79.5% of samples harbored ≥1 actionable biomarker, with the most frequently altered genes being TP53, KRAS, PIK3CA, EGFR, and NF1. Overall, 42.6% of samples had ≥1 biomarker with an indication in the patient’s cancer type, including 81.5% of lung, 59.0% of breast, 61.8% of colorectal, and 42.1% of prostate cancers. Across the pan-cancer cohort, 13.3% was TMB-high and 1.9% was MSI-high. 26.3% of samples were from cancer types outside the original assay design; the top 3 were pancreatic cancer (7.3%), sarcoma (3.3%), and CNS tumor (3.1%). Cancers of unknown primary (CUP) also constituted a significant proportion (3.8%). In CNS tumors, 38.7% harbored an actionable mutation in IDH1, BRAF, or H3-3A. In CUP, 78.8% harbored an actionable mutation; 50% of samples harbored biomarkers that additionally informed potential tumor origin, including mutations in EGFR, MET, ALK, ROS1, and BRCA1. Conclusion: The use of an Asian-focused pan-cancer DNA/RNA NGS panel resulted in detection of actionable biomarkers in 79.5% of clinical cases. These findings support the utility of DNA/RNA NGS assays in informing standard-of-care therapeutic decisions in Asian cancer patients for maximizing cancer survival. Citation Format: Jason Yongsheng Chan, Jing Yi Lee, Zi Yi Wan, Abner Herbert Lim, Tun Kiat Ko, Cedric Chuan-Young Ng, Donald Poon, Jens Samol, Tsz Him So, Su Pin Choo, Ravindran Kanesvaran, Cheng-Vai Hui, Joseph Siu-Kie Au, Aya El Helali, Timothy Yip, Vikneswari Rajasegaran, Sandy Lim, Ruifen Weng, Puay Hoon Tan, Bin Tean Teh, Min-Han Tan, Jonathan Poh. Real-world experience of an Asian pan-cancer combined DNA/RNA next generation sequencing (NGS) tissue biopsy assay [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 6399.
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f, f. "The Perception Structure of the man and nature in Ancient Chinese as Seen in Huai nan zi". Society for Chinese Humanities in Korea 85 (31 de dezembro de 2023): 227–46. http://dx.doi.org/10.35955/jch.2023.12.85.227.

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This paper focuses on exploring the relationship between the human body, mind, and the universe as seen in “Huai nan zi”, and identifying its integrated points. Through this, it seeks to gain insights into the essence of ancient Chinese philosophy and culture while finding clues to solve various problems that humanity faces today. In the first chapter, it delves into the interconnectivity of humans, the Tao, and the universe. Through the sentences in “Huai nan zi”, it examines the nature and principles of the universe that ancient Chinese people had explored. Clearly recorded within are the characteristics of time, space, and the relative properties of all things, such as Yin and Yang. These people would have awakened to the world with the intuition that they themselves are microcosms, parts and wholes of the Tao. In the second chapter, the theme of the recognition of light and the regression to the interior is dealt with. It discusses that in the process of irradiating the human body with light to return to a state of complete purification, or true brightness, countless repetitions overcome all kinds of physical discomforts, which then extend to the realm of the inner mind. In the third chapter, it discusses the world sensitivity of a sage, based on the ontological insights of the self and the material. In the “Yuan dao xun” section of “Huai nan zi”, it is emphasized that the satisfaction that humans actually have does not lie in the external material enjoyment, but rather, one can feel the tranquility of the mind again when one focuses on the inner peace. It argues that through this, one can experience the value and beauty of life and reach the boundary of a higher dimension.
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LEE, Sun-hee. "《中華字經》在對外漢語詞彙教學中應用研究". International Journal of Chinese Character Studies 6, n.º 2 (31 de dezembro de 2023): 233–47. http://dx.doi.org/10.18369/waccs.2023.6.2.233.

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Han (韓東育), Dongyu. "The Rise and Fall of the Hua-Yi System in East Asia". Journal of Chinese Humanities 5, n.º 2 (6 de julho de 2020): 200–214. http://dx.doi.org/10.1163/23521341-12340080.

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Abstract The Hua-Yi 華夷 system that spread in East Asia in the form of tribute relationships during the Ming dynasty [1368-1644] began as a system based on China’s perceived cultural superiority, but slowly evolved into a system centered on nationalism. Accordingly, the kinship networks embedded in the Hua-Yi system were also continually evolving, breaking down, and reforming in a cycle that repeated itself multiple times. Amid this process, ethnocentrism [zi minzu zhongxin zhuyi 自民族中心主義] and “interest centralism” [liyi zhongxin zhuyi 利益中心主義] played key roles in the formation and eventual dissolution of the Hua-Yi system.
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이미옥. "A Comparative Study on the Poems by Gi Hyeong-do and Hai Zi". Journal of North-east Asian Cultures 1, n.º 57 (dezembro de 2018): 17–37. http://dx.doi.org/10.17949/jneac.1.57.201812.002.

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WU, HUIYING. "The "Alienation" aspect of Gi Hyeong-do and Hai Zi "s poetic subject". Chunwon Research journal 18 (31 de agosto de 2020): 161–80. http://dx.doi.org/10.31809/crj.2020.08.18.161.

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Төрбат, Цагаан. "Ашина овгийн хатны эртний геном нь Хөх түрэгийн хаант улсыг Зүүн хойд Азийн гаралтай болохыг харуулжээ". Mongolian Journal of Anthropology, Archaeology and Ethnology 13, n.º 1 (10 de maio de 2024): 141–45. http://dx.doi.org/10.22353/mjaae.20241301013.

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Xiao‐Min Yang, Hai‐Liang Meng, Jian‐Lin Zhang, Yao Yu, Edward Allen, Zi‐Yang Xia, Kong‐Yang Zhu, Pan‐Xin Du, Xiao‐Ying Ren, Jian‐Xue Xiong, Xiao‐Yu Lu, Yi Ding, Sheng Han, Wei‐Peng Liu, Li Jin, Chuan‐Chao Wang, and Shao‐Qing Wen. Ancient genome of Empress Ashina reveals the Northeast Asian origin of Göktürk Khanate. – Journal of Systematic and Evolution. Institute of Botany, Chinese Academy of Sciences. 2023. Volume 00 (0) 1-9.
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Marlim, Yenny, e Therecia Oscar. "EXPRESSIONS OF CRITICSM TOWARDS SOCIAL PROBLEMS IN POETRY FROM ANCIENT AGE, MODERN AGE, AND CONTEMPORARY AGE". Journal of Language, Literature, and Teaching 4, n.º 3 (20 de março de 2023): 27–39. http://dx.doi.org/10.35529/jllte.v4i3.27-39.

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The purpose of this research is to reveal the forms of ancient, modern and contemporary poetry in expressing social problems and the reasons for the expressions of social criticism. The design of this research is a descriptive qualitative. The objects of the research are the forms of expression towards social criticism and the reasons behind them which are found in the ancient Tang poetry “Zi Jing Fu Feng Xian Xian Yong Huai Wu Bai Zi自京赴奉先县咏怀五百字”, the modern poetry “Da Yan He Wo - De Bao大堰河——我的保姆”, and the contemporary poetry “Xiang Chou乡愁”. The results of the research show that there are 26 forms of expression of social criticism in the three poems, including 13 straightforward social criticism (50%), 6 symbolic social criticism (23.08%), 2 cynical social criticism (7.69%) and 5 explanatory social criticism (19.23%). There are three reasons for the expressions of social criticism: (1) the historical aspect (national administration), (2) psychological aspect (sharpening the author's expression attitude), and (3) imagery. Key Words: Social Criticism, Expressions Form, Poem
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Dongin Park. "Huai-Nan-Zi 's the View of Life and Death and the View of Ego". Studies in Confucianism 33, n.º ll (novembro de 2015): 387–416. http://dx.doi.org/10.18216/yuhak.2015.33..015.

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Mietzner, A. "Porträt chinesischer Arzneimittel bei Augenerkrankungen: Chrysanthemi Flos (ju hua) und Lycii Fructus (gou qi zi)". Deutsche Zeitschrift für Akupunktur 58, n.º 4 (2015): 46–47. http://dx.doi.org/10.1016/s0415-6412(15)30077-1.

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Yuan, Xiao Hui, e Zhe An Lu. "Stress Performance Analysis on New Type of Concrete-Filled Steel Tube Pre-Stressed Truss Continuous Beam Bridge". Applied Mechanics and Materials 271-272 (dezembro de 2012): 1415–20. http://dx.doi.org/10.4028/www.scientific.net/amm.271-272.1415.

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This paper takes the construction of Gan Hai-zi concrete-filled steel tube pre-stressed continuous truss Beam Bridge as the engineering background. Combined with the actual construction process of the bridge, taken the main structure of the bridge as the typical prestressed composite structure and used the finite element joint section to simulation the whole construction process of the 35th and 36th experimental cross composite structure of the bridge. Theoretical analysis combined with the field test, and the calculation results are in good agreement with the experimental results,which shows that the construction mechanical performance of the new bridge structure is good.
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Qi, Zeng, Zhuo Li, Xuewa Guan, Cuizhu Wang, Fang Wang, Pingya Li e Jinping Liu. "Four Novel Dammarane-Type Triterpenoids from Pearl Knots of Panax ginseng Meyer cv. Silvatica". Molecules 24, n.º 6 (23 de março de 2019): 1159. http://dx.doi.org/10.3390/molecules24061159.

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Panax ginseng Meyer cv. Silvatica (PGS), which is also known as “Lin-Xia-Shan-Shen” or “Zi-Hai” in China, is grown in forests and mountains by broadcasting the seeds of ginseng and is harvested at the cultivation age of 15–20 years. In this study, four new dammarane-type triterpenoids, ginsengenin-S1 (1), ginsengenin-S2 (2), ginsenoside-S3 (3), ginsenoside-S4 (4), along with one known compound were isolated from pearl knots of PGS. Ginsengenin-S2 significantly alleviated oxidative damage when A549 cells were exposed to cigarette smoke (CS) extract. In addition, ginsengenin-S2 could inhibit the CS-induced inflammatory reaction in A549 cells. Protective effects of ginsengenin-S2 against CS-mediated oxidative stress and the inflammatory response in A549 cells may involve the Nrf2 and HDAC2 pathways.
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종선홍. "Contradiction of Mind of Zhu-Zi Qing : Based on 《Jiang Sheng Peng Ying li de Qin Huai-He》". Journal of Foreign Studies 14, n.º 1 (junho de 2010): 413–26. http://dx.doi.org/10.15755/jfs.2010.14.1.413.

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Chen, Jun Hao, e Rui Zhang. "The Field Measure of Special Strata Freezing Temperature in West Area". Applied Mechanics and Materials 170-173 (maio de 2012): 1207–10. http://dx.doi.org/10.4028/www.scientific.net/amm.170-173.1207.

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A new round of upsurge of mine well construction were set off in the west area, but there are many problems, this article through the field measure of special strata freezing temperature in Bo-jiang-hai-zi coal mine airshaft, use the freezing shaft sinking security information network visualization platform that developed by Anhui University of Science and Technology, analysis several different strata, obtain the overall temperatre decline rate, and compare the difference between in-site shaft well temperature and the calculation value at different position, and difference is very small, it shows that the platform can good response the actual situation. Through calculation, the frozen wall thickness, average of frozen wall temperature, shaft well temperature are meet the engineering design requirement, so propose that in west area at the freezing method mine well construction, the main purpose is waterproof, and use single circle tube freezing can satisfy engineering design requirements.
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Batten, DJ, e E. Lahav. "Base Temperatures for Growth Processes of Lychee, a Recurrently Flushing Tree, Are Similar but Optima Differ". Functional Plant Biology 21, n.º 5 (1994): 589. http://dx.doi.org/10.1071/pp9940589.

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Potted plants of cultivars 'Haak Yip' (Hei Ye), 'Tai So' (Da Zao) and 'Bengal' were grown in temperature-controlled glasshouse rooms at 10, 15, 20, 25, 30 or 35�C to determine cardinal temperatures for various growth processes. At other times plants of cvv. 'Brewster' (Chen Zi), 'Kwai May Pink' and 'Wai Chee' (Huai Zhi) were grown at various constant temperatures and cvv. 'Tai So' and 'Wai Chee' were grown at 27/21�C and 18/12�C (12 h day/12 h night). A modified Richards' function accurately described leaflet elongation with time. Functions fitted to derived parameters of maximum relative elongation rate and duration allowed the accurate determination of minimum and optimum cardinal temperatures for leaflet elongation. The maximum temperature for leaf elongation was well in excess of 35�C. Other processes studied included shoot elongation, increase in leaf area per plant, dry matter (DM) production, new shoot DM, DM partitioning between roots, shoots and leaves, flush periodicity, leaf morphology and total non-structural carbohydrate (TNSC) status. The minimum temperatures were similar for different processes whereas the optimum temperatures determined were different. These are compared, along with data from published studies on other physiological processes of lychee. Leaflet elongation occurred at a significantly higher optimum temperature than DM accumulation, a difference which could not be attributed to effects of temperature on partitioning, and is probably facilitated by the recurrent flushing mode of growth of lychee. There were few differences between the cultivars. 'Haak Yip' growth appeared to be more tolerant of high temperatures than 'Tai So' or 'Bengal' and 'Bengal' had higher leaf concentrations of TNSC at moderate to high temperatures. A model relating shoot periodicity to temperature (heat units) is suggested which could help in studying the relationship between flushing and flower initiation.
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Шань, Н., e С. Ван. "Yesenin’s poetic heritage and its impact on the new “rustic” Chinese poetry of early 90s". Иностранные языки в высшей школе, n.º 2(65) (14 de agosto de 2023): 64–73. http://dx.doi.org/10.37724/rsu.2023.65.2.009.

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Китайские и российские ученые рассматривали влияние есенинской поэзии на китайскую в целом и на творчество Хай-цзы в частности. Однако отражение поэтического наследия Есенина в новой деревенской поэзии Китая начала 90-х годов XX века пока не полностью изучено. В связи с тем, что современная китайская поэзия обладает жанровым и стилистическим разнообразием, авторы статьи предприняли попытку перевести пять стихотворений посредством верлибра — стиха со свободной рифмой, то есть как с рифмой, так и без нее. Актуальность предлагаемого исследования обусловлена необходимостью осмысления практических путей перевода современной новодеревенской поэзии на русский язык. Both Chinese and Russian scholars studied the influence of Sergei Yesenin’s poetic heritage on Chinese poetry ingeneral and the works of Hai Zi, in particular. Yet little attention has been so far given to the spiritual connection between Yesenin’s poetic world vision and that of the modern representatives of the so-called “rustic” poetry. The paper traces the influence of Yesenin on the inherent qualities of modern “rustic” Chinese poetry — on its thematic scope, imagery, tonality. Since modern Chinese poetry is characterized by genre and style variations, the paper offers five vers libre translations of well-known contemporary Chinese poets. The article is expected to draw attention to the necessity of looking for adequate ways of rendering in Russian the philosophic and emotional impact of modern “rustic” poetry and its tonality.
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지준호. "A Study on the differentiation and development aspects of Zhu-zi xue - centering around the connection between Huang Gan and Jin-hua school in Yuan period". JOURNAL OF KOREAN PHILOSOPHICAL HISTORY ll, n.º 23 (março de 2008): 317–47. http://dx.doi.org/10.35504/kph.2008..23.011.

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Park, Jong-Haak. "A Study on a Concept of “Xing(形)” ․ “Shen(神)” Existing in the Human Mind -Focusing on the thoughts in Dao jia and Huai nan zi". Korean Society of Culture and Convergence 42, n.º 10 (30 de outubro de 2020): 15–35. http://dx.doi.org/10.33645/cnc.2020.10.42.10.15.

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Li, Yi-Dong, Yong Mao, Xing-Duo Dong, Zi-Ning Lei, Yuqi Yang, Lizhu Lin, Dong-Hua Yang e Zhe-Sheng Chen. "Abstract 360: Methyl-cantharidimide (MCA) can induce apoptosis by activating UNC5B-Netrin-1-DAPK pathway in hepatocellular carcinoma". Cancer Research 82, n.º 12_Supplement (15 de junho de 2022): 360. http://dx.doi.org/10.1158/1538-7445.am2022-360.

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Abstract In this study, we investigated the underlying mechanism of action of methyl-cantharidimide (MCA), a cantharidin (CTD) analog, as an anticancer drug, in resistant cancer cells overexpressing either ABCB1 or ABCG2 and in cisplatin-resistant cancer cells. The results indicated that: (i) MCA was efficacious in the ABCB1-overexpressing cell line, KB-C2, the ABCG2-overexpressing cell line, NCI-H460/MX20 and in the cisplatin resistant cancer cell lines, KCP-4 and BEL-7404/CP20; (ii) MCA induced apoptosis in both BEL-7404 and BEL-7404/CP20 cancer cells and arrested both BEL-7404 and BEL-7404/CP20 cancer cells in the G0/G1 phase of the cell cycle; (iii) MCA upregulated the expression level of the protein, unc-5 netrin receptor B (UNC5B) in HepG2 and BEL-7404 cancer cells. (iv) MCA can activate UNC5B-Netrin-1-DAPK apoptosis pathway in hepatocellular carcinoma cells. Overall, our results indicated that MCA's efficacy in multiple cancer cell lines is due to the activation of UNC5B-Netrin-1-DAPK apoptosis pathway and cell cycle arrest in the G0/G1 phase. Citation Format: Yi-Dong Li, Yong Mao, Xing-Duo Dong, Zi-Ning Lei, Yuqi Yang, Lizhu Lin, Dong-Hua Yang, Zhe-Sheng Chen. Methyl-cantharidimide (MCA) can induce apoptosis by activating UNC5B-Netrin-1-DAPK pathway in hepatocellular carcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 360.
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Kuo, Yi-Ting, Hou-Hsun Liao, Jen-Huai Chiang, Mei-Yao Wu, Bor-Chyuan Chen, Ching-Mao Chang, Ming-Hsien Yeh et al. "Complementary Chinese Herbal Medicine Therapy Improves Survival of Patients With Pancreatic Cancer in Taiwan: A Nationwide Population-Based Cohort Study". Integrative Cancer Therapies 17, n.º 2 (3 de agosto de 2017): 411–22. http://dx.doi.org/10.1177/1534735417722224.

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Background: Pancreatic cancer is a difficult-to-treat cancer with a late presentation and poor prognosis. Some patients seek traditional Chinese medicine (TCM) consultation. We aimed to investigate the benefits of complementary Chinese herbal medicine (CHM) among patients with pancreatic cancer in Taiwan. Methods: We included all patients with pancreatic cancer who were registered in the Taiwanese Registry for Catastrophic Illness Patients Database between 1997 and 2010. We used 1:1 frequency matching by age, sex, the initial diagnostic year of pancreatic cancer, and index year to enroll 386 CHM users and 386 non-CHM users. A Cox regression model was used to compare the hazard ratios (HRs) of the risk of mortality. The Kaplan-Meier curve was used to compare the difference in survival time. Results: According to the Cox hazard ratio model mutually adjusted for CHM use, age, sex, urbanization level, comorbidity, and treatments, we found that CHM users had a lower hazard ratio of mortality risk (adjusted HR = 0.67, 95% CI = 0.56-0.79). Those who received CHM therapy for more than 90 days had significantly lower hazard ratios of mortality risk than non-CHM users (90- to 180-day group: adjusted HR = 0.56, 95% CI = 0.42-0.75; >180-day group: HR = 0.33, 95% CI = 0.24-0.45). The survival probability was higher for patients in the CHM group. Bai-hua-she-she-cao (Herba Oldenlandiae; Hedyotis diffusa Spreng) and Xiang-sha-liu-jun-zi-tang (Costus and Chinese Amomum Combination) were the most commonly used single herb and Chinese herbal formula, respectively. Conclusions: Complementary Chinese herbal therapy might be associated with reduced mortality among patients with pancreatic cancer. Further prospective clinical trial is warranted.
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Stern, R. A., D. Stern, H. Miller, H. F. Xu e S. Gazit. "THE EFFECT OF THE SYNTHETIC AUXINS 2,4,5-TP AND 3,5,6-TPA ON YIELD AND FRUIT SIZE OF YOUNG ‘FEI ZI XIAO’ AND ‘HEI YE’ LITCHI TREES IN GUANGXI PROVINCE, CHINA". Acta Horticulturae, n.º 558 (agosto de 2001): 285–88. http://dx.doi.org/10.17660/actahortic.2001.558.45.

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Teng, Qiu-Xu, Zi-Ning Lei, Wei Zhang, Ying-Fang Fan, Jing-Quan Wang, Chao-Yun Cai, Dong-Hua Yang, John Wurpel e Zhe-Sheng Chen. "Abstract 1095: Establishment and characterization of a topotecan resistant lung cancer NCI H460/TPT10 cell line and a tumor xenograft model". Cancer Research 82, n.º 12_Supplement (15 de junho de 2022): 1095. http://dx.doi.org/10.1158/1538-7445.am2022-1095.

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Abstract While topotecan (TPT) is a chemotherapeutic drug in treating lung cancer, the development of TPT resistance in tumors reserves as a major obstacle to chemotherapeutic success. Therefore, a better understanding of the mechanisms of TPT resistance is critical. In this study, the first topotecan-resistant human non-small cell lung cancer (NSCLC) cell line, termed NCI-H460/TPT10, was established from the parental NCI-H460 cell line. NCI-H460/TPT10 cells exhibited a 394.7-fold resistance to TPT, and cross-resistance to SN-38, mitoxantrone, and doxorubicin, compared to parental NCI-H460 cells. Overexpression of ABCG2 localized on the cell membrane, but not ABCB1 or ABCC1, was found in NCI-H460/TPT10 cells, indicating that ABCG2 was likely to be involved in TPT-resistance. This was confirmed by the abolishment of drug resistance in NCI-H460/TPT10 cells after ABCG2 knockout. Moreover, the involvement of functional ABCG2 as a drug efflux pump conferring multidrug resistance (MDR) was indicated by low intracellular accumulation of TPT in NCI-H460/TPT10 cells, and the reversal effects by ABCG2 inhibitor Ko143 and cabozantinib. The NCI-H460/TPT10 and its parental cell line were further used to establish in vivo tumor xenograft mouse models, which verified their capability to serve as clinically relevant models for drug screening and the development of targeted strategies to overcome ABCG2-mediated MDR in NSCLC. Citation Format: Qiu-Xu Teng, Zi-Ning Lei, Wei Zhang, Ying-Fang Fan, Jing-Quan Wang, Chao-Yun Cai, Dong-Hua Yang, John Wurpel, Zhe-Sheng Chen. Establishment and characterization of a topotecan resistant lung cancer NCI H460/TPT10 cell line and a tumor xenograft model [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 1095.
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Zhao, Ping. "A comparative study on the critical recognition of reality between Korean and Chinese Poetry in the 1980s ― focused on the poem of Hwang Ji-woo, Park Nam-cheol and Bei Dao, Hai Zi". JOURNAL OF MODERN LITERARY THEORY 75 (31 de dezembro de 2018): 321–54. http://dx.doi.org/10.22273/smlt.75.14.

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Zhou, Jun, Zi Ye, Ning Bo, Dan Zhang, Li Hua, Chenpan Nie, Jingjing Wang, Rajendra Kumari, Leo Price e Xiaoxi Xu. "Abstract 401: Developing KRAS G12C inhibitor-resistant tumor models for efficacy evaluation of next-generation anticancer therapies". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 401. http://dx.doi.org/10.1158/1538-7445.am2023-401.

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Abstract Background: AMG510, a novel KRAS G12C mutation-specific inhibitor approved in 2021 by FDA, was the first therapy to directly target the KRAS oncoprotein in KRAS-mutant cancers with other direct KRAS G12C inhibitors currently being investigated in multiple clinical trials. However, the emergence of resistance in patients who initially were responsive is a challenge. Uncovering the underlying mechanism of resistance would support the identification and development of novel therapies to overcome drug resistance. In this study, we generated a panel of KRAS G12C inhibitor-resistant tumor models by introducing a secondary KRAS mutation on top of G12C for use as in vitro and in vivo tools to develop possible strategies to overcome such resistance. Methods: First, by using CRISPR/Cas9, we introduced a secondary KRAS mutation, including Y96C, Y96D and Y96S in MIA PaCa, which harbours a homozygous KRAS G12C mutation. Point mutation knock-in was validated by sanger sequencing and cell identity was confirmed by SNP. Then cell viability was measured by CellTiter-Glo after 5 days incubation with AMG510 and MRTX849. RAS-MAPK pathway activity was assessed in the parental and mutant cell lines Y96D by Western blot. Xenograft of MIA PaCa KRAS G12C/Y96D cells l was also established. Results: Successful homozygous point mutation knock-in was achieved as confirmed by sanger sequencing. The double mutant cells displayed the similar growth rate as well as the morphology. In cell viability assays, relative to KRAS G12C parental cells, cells expressing the double-mutant alleles showed marked resistance to AMG510 and MRTX849. Consistent with the effects on cell viability, persistent phosphorylated ERK (pERK) and pRSK levels was also observed in KRAS G12C/Y96D expressing cells even at high concentrations of MRTX849, indicating sustained RAS-MAPK activity. In addition, MIA PaCa-KRAS G12C/Y96D was able to grow in vivo and will be used for pharmacological evaluation of KRAS inhibitors. Conclusion: These double-mutant cells can be used to assess preclinical in vitro/in vivo efficacy of KRAS-targeted therapeutics. Crown Bioscience is in the process of developing a series of KRAS G12C inhibitor-resistant cell lines to better facilitate efficacy testing of KRAS-targeted therapeutics. Citation Format: Jun Zhou, Zi Ye, Ning Bo, Dan Zhang, Li Hua, Chenpan Nie, Jingjing Wang, Rajendra Kumari, Leo Price, Xiaoxi Xu. Developing KRAS G12C inhibitor-resistant tumor models for efficacy evaluation of next-generation anticancer therapies [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 401.
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Qian, Kun, Bin Hu, Ming He, Zi-Tong Wang, Yu Liu, Hua-Gang Liang, Zhi-Yong Su, Yu-Shang Cui, Li-Jun Liu e Yi Zhang. "Abstract 5499: Efficacy of icotinib as adjuvant therapy for patients with stage IIA-IIIA EGFR-mutant non-small-cell lung adenocarcinoma: a multicenter, open-label, single-arm, phase II study (ICAPE)". Cancer Research 82, n.º 12_Supplement (15 de junho de 2022): 5499. http://dx.doi.org/10.1158/1538-7445.am2022-5499.

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Abstract Background: Currently, epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) have been proved to significantly improve the clinical outcome of patients with EGFR-mutant non-small-cell lung cancer (NSCLC). Icotinib is an oral, reversible and selective first-generation EGFR-TKI. The survival benefits of 1-year and 2-year adjuvant icotinib in patients with EGFR-mutant NSCLC have been confirmed in previous studies. However, the optimal duration of adjuvant icotinib remains unknown. This study (ICAPE) evaluated the efficacy of 1.5-year adjuvant therapy with icotinib for patients with stage IIA-IIIA EGFR-mutant non-small-cell lung adenocarcinoma. Methods: Patients with stage IIA-IIIA EGFR-mutant non-small-cell lung adenocarcinoma were enrolled in the multicenter, open-label, single-arm, phase II study. Eligible patients received oral icotinib 125 mg thrice daily for 1.5 years after complete surgical resection. Primary endpoint was disease-free survival (DFS). Secondary endpoints included 1-year, 3-year, as well as 5-year OS rates, and the DFS according to the BIM mutation status (mutant-type and wild-type) and EGFR mutation types (19 del and 21 L858R). Results: Between March 2014 and January 2018, 79 patients were enrolled. The median follow-up time was 39.7 months with a median DFS and overall survival (OS) of 41.4 months (95% CI: 33.6-51.8) and 67.0 months (95% CI: 21.2-not reached [NR]), respectively. The 1-year, 3-year and 5-year OS rates were 100%, 83.3%, and 61.7%, respectively. No significant difference was found in the median DFS between patients with Bcl-2 interacting mediator of cell death (BIM) mutant-type and wild-type (NR vs. 41.7 months; p=0.75) and no significant difference was found in the median DFS according to EGFR mutation types (all p&gt;0.05). Conclusions: The phase II ICAPE study demonstrated that 1.5-year adjuvant therapy with icotinib had a favorable survival benefit in patients with stage IIA-IIIA EGFR-mutant non-small-cell lung adenocarcinoma with a long median DFS and high 5-year OS rates which is consistent with other icotinib’s study. Icotinib is suggested to be used as an adjuvant therapy option in IIA-IIIA EGFR-mutant non-small-cell lung adenocarcinoma. Citation Format: Kun Qian, Bin Hu, Ming He, Zi-Tong Wang, Yu Liu, Hua-Gang Liang, Zhi-Yong Su, Yu-Shang Cui, Li-Jun Liu, Yi Zhang. Efficacy of icotinib as adjuvant therapy for patients with stage IIA-IIIA EGFR-mutant non-small-cell lung adenocarcinoma: a multicenter, open-label, single-arm, phase II study (ICAPE) [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5499.
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Tian, Nai-Feng, e Fang-Min Mao. "Answer to the Letter to the Editor of Feng Li et al. entitled “Minimally invasive versus open transforaminal lumbar interbody fusion: a meta-analysis based on the current evidence” by Nai-Feng Tian, Yao-Sen Wu, Xiao-Lei Zhang, Hua-Zi Xu, Yong-Long Chi, Fang-Min Mao (2013). Eur Spine J, doi:10.1007/s00586-013-2747-z". European Spine Journal 23, n.º 4 (18 de janeiro de 2014): 929–30. http://dx.doi.org/10.1007/s00586-014-3185-2.

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Harper, Donald. "The Textual History of the Huai-nan Tzu. By Harold D. Roth. Ann Arbor: AAS Monograph Series No. 46, 1992. xvi, 470 pp. $36.00 (cloth); $20.00 (paper). - Mythe et Philosophie à l'Aube de la Chine Impériale: Études sur le Huainan Zi. Edited by Charles LeBlanc and Rémi Mathieu. Montreal, Paris: Les Presses de l'Université de Montréal, 1992. xxvi, 240 pp." Journal of Asian Studies 52, n.º 4 (novembro de 1993): 991–92. http://dx.doi.org/10.2307/2059368.

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柯香君, 柯香君. "《高文舉》版本考述". 中正漢學研究 37, n.º 37 (junho de 2021): 281–332. http://dx.doi.org/10.53106/2306036020210600370010.

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<p>「高文舉故事」始自形成,便以多元樣貌流播於各地聲腔,依據本文所較析的四個版本,彼此間存在著複雜關係,或有獨立發展者,如南管戲《高文舉》,或有屬古本系統者,如《水雲亭還魂記》,或有保留南戲原貌者莆仙戲《高文舉》,乃至於集大成者「文林閣本」《高文舉珍珠記》。南戲《高文舉》已亡佚,其中以《高文舉珍珠記》之影響最為深遠。「高文舉故事」主要情節有三:「珍珠米糷」、「還魂訴冤」、「包拯斷案」。在「文林閣本」與「莆仙本」皆有「珍珠米糷」、「龍圖斷案」,而「還魂本」有「玉真還魂」、「龍圖斷案」,至於「南管本」則一概具無,可知「南管本」在高文舉故事流變過程中之獨特性。本文主要針對各版本間之「關目情節」、「曲文賓白」等詳實比勘,剖析「高文舉」在不同聲腔劇種間之承繼與創新,並試圖重構各地聲腔在「高文舉」演化過程中之地位與價值。</p> <p>&nbsp;</p><p>Gao Wen Jyu of southern opera has been disappeared and present versions include Zhen Zhu Ji (Yi Yang tune), Gao Wen Jyu of Southern Pipes (Quan tune), Gao Wen Jyu of Pu Xian (Hsin Hua tune) and Revival After Death of Shui Yun Pavilion (Qing Yang tune). Among others, Zhen Zhu Ji is the most influential one. The plots such as &ldquo;Window Meeting&rdquo; and &ldquo;Zhen Zhu Mi Lan&rdquo; are not only the selected Zhe Zi operas for the later generations, but also the adapted texts of local operas. Main plots of &ldquo;story of Gao Wen Jyu&rdquo; are below: &ldquo;Zhen Zhu Mi Lan&rdquo;, &ldquo;Revival After Death to Appeal for Justice&rdquo; and &ldquo;Master Pao&rsquo;s Judgment&rdquo;. Zhen Zhu Ji and &ldquo;version of Pu Xian&rdquo; include &ldquo;Zhen Zhu Mi Lan&rdquo; and &ldquo;Master Pag&rsquo;s Judgment&rdquo;. &ldquo;Version of revival after death&rdquo; includes &ldquo;Revival After Death of Yu Chen&rdquo; and &ldquo;Master Pao&rsquo;s Judgment&rdquo;. &ldquo;Version of Southern Pipes&rdquo; does not include the above. Hence, it shows the uniqueness of &ldquo;version of Southern Pipes&rdquo; in the evolution of &ldquo;story of Gao Wen Jyu&rdquo;. Varieties of plots result in the richness of &ldquo;story of Gao Wen Jyu&rdquo;. The process of spread reveals flexibility and regionality of local common systematic tunes and varieties of operas. </p> <p> This study will treat four versions of Gao Wen Jyu as the subjects to significantly compare and analyze the original stories and difference and similarity of related work. First, it explores present versions to recognize the evolution of the story &ldquo;Gao Wen Jyu&rdquo;; secondly, it precisely compares &ldquo;plots&rdquo; and &ldquo;singing and talking&rdquo; of the versions to analyze the inheritance and innovation of &ldquo;story of Gao Wen Jyu&rdquo; in different common systematic tunes and varieties of Chinese operas. It, on the one hand, clarifies the relationship and origin of different versions of &ldquo;Gao Wen Jyu&rdquo; and, on the other hand, probes into cultural characteristics of &ldquo;time&rdquo; and &ldquo;region&rdquo; of operas; finally, it attmpets to reconstruct the positions and values of common systematic tunes in different regions in the evolution process of &ldquo;Gao Wen Jyu&rdquo;. </p> <p>&nbsp;</p>
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Erpelding, John E. "Genetics of the fuzzless ovule phenotype of Gossypium arboreum accession PI 615733 (cv. Zi-Hua Guang Zi)". Crop Breeding and Applied Biotechnology 20, n.º 4 (2020). http://dx.doi.org/10.1590/1984-70332020v20n4a57.

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Cao, Dong-Ling, Xue-Jie Zhang, Shao-Qiu Xie, Shou-Jin Fan e Xiao-Jian Qu. "Application of chloroplast genome in the identification of Traditional Chinese Medicine Viola philippica". BMC Genomics 23, n.º 1 (27 de julho de 2022). http://dx.doi.org/10.1186/s12864-022-08727-x.

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Abstract Background Viola philippica Cav. is the only source plant of “Zi Hua Di Ding”, which is a Traditional Chinese Medicine (TCM) that is utilized as an antifebrile and detoxicant agent for the treatment of acute pyogenic infections. Historically, many Viola species with violet flowers have been misused in “Zi Hua Di Ding”. Viola have been recognized as a taxonomically difficult genera due to their highly similar morphological characteristics. Here, all common V. philippica adulterants were sampled. A total of 24 complete chloroplast (cp) genomes were analyzed, among these 5 cp genome sequences were downloaded from GenBank and 19 cp genomes, including 2 “Zi Hua Di Ding” purchased from a local TCM pharmacy, were newly sequenced. Results The Viola cp genomes ranged from 156,483 bp to 158,940 bp in length. A total of 110 unique genes were annotated, including 76 protein-coding genes, 30 tRNAs, and four rRNAs. Sequence divergence analysis screening identified 16 highly diverged sequences; these could be used as markers for the identification of Viola species. The morphological, maximum likelihood and Bayesian inference trees of whole cp genome sequences and highly diverged sequences were divided into five monophyletic clades. The species in each of the five clades were identical in their positions within the morphological and cp genome tree. The shared morphological characters belonging to each clade was summarized. Interestingly, unique variable sites were found in ndhF, rpl22, and ycf1 of V. philippica, and these sites can be selected to distinguish V. philippica from samples all other Viola species, including its most closely related species. In addition, important morphological characteristics were proposed to assist the identification of V. philippica. We applied these methods to examine 2 “Zi Hua Di Ding” randomly purchased from the local TCM pharmacy, and this analysis revealed that the morphological and molecular characteristics were valid for the identification of V. philippica. Conclusions This study provides invaluable data for the improvement of species identification and germplasm of V. philippica that may facilitate the application of a super-barcode in TCM identification and enable future studies on phylogenetic evolution and safe medical applications.
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Guo, Cui, Xingdong Kang, Fang Cao, Jian Yang, Yimin Xu, Xiaoqiang Liu, Yuan Li, Xiumei Ma e Xiaoling Fu. "Network Pharmacology and Molecular Docking on the Molecular Mechanism of Luo-hua-zi-zhu (LHZZ) Granule in the Prevention and Treatment of Bowel Precancerous Lesions". Frontiers in Pharmacology 12 (15 de fevereiro de 2021). http://dx.doi.org/10.3389/fphar.2021.629021.

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The Luo-hua-zi-zhu (LHZZ) granule has been widely used for the treatment of colorectal adenoma (CRA), which is a precursor of colorectal cancer (CRC). However, the active components of LUZZ and its mechanism of action against CRA have not yet been elucidated. This study was designed to investigate the effect of LHZZ on CRA and explore its pharmacological mechanisms. First, a total of 24 chemical constituents were identified in the 50% aqueous methanol extract of LHZZ granule based on the mass fragment patterns and mass spectral library using the high resolution UPLC-Q-TOF MS/MS system. Subsequently, based on a network pharmacology study, 16 bioactive compounds and 28 targets of the LHZZ associated with CRA were obtained, forming a compound-target network. Molecular docking tests showed tight docking of these compounds with predicted targeted proteins. The protein–protein interaction (PPI) network identified AKT1, CASP3, TP53 and EGFR as hub targets. The Kyoto Encyclopedia of Genes and Genomes pathway network and pathway-target-compound network revealed that the apoptosis pathway was enriched by multiple signaling pathways and multiple targets, including the hub targets. Finally, the reliability of the core targets was evaluated using molecular docking technology and in vitro studies. Our study indicated that the LHZZ particle has preventive and treatment effect on colorectal adenoma through multi-component, multi-target and multi-pathway.
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"Yi da li yu ge ju jiao ben zi dui zi jing zhun jie xi xi lie cong shu ed. by Stella Chen Guo and Carlo Alberto Petruzzi, and: "Ai de gan chun" zi dui zi jing zhun jie xi by Felice Romani, and: "Cha hua nü" zi dui zi jing zhun jie xi by Francesco Maria Piave, and: "Nong chen" zi dui zi jing zhun jie xi by F. M. Piave, and: "Tuo si ka" zi dui zi jing zhun jie xi by Giuseppe Giacosa and Luigi Illica, and: "Yi shu jia de sheng ya" zi dui zi jing zhun jie xi by G. Giacosa and L. Illica, and: "Xiang cun qi shi—Cho jue" zi dui zi jing zhun jie xi by Giovanni Targioni-Tozzetti, Guido Menasci, and Ruggiero Leoncavallo (review)". Notes 80, n.º 1 (setembro de 2023): 145–49. http://dx.doi.org/10.1353/not.2023.a905328.

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"Discussion on efficacy of traditional Chinese medicine "Zi-hua Qianhu" in Chinese Pharmacopoeia(2010 Edition)". China Journal of Chinese Materia Medica, 15 de junho de 2015. http://dx.doi.org/10.4268/cjcmm20151238.

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Huang, Guangzhe. "Reframing Zhuangzi through recontextualization". Babel / Revue internationale de la traduction / International Journal of Translation / Revista Internacional de Traducción, 11 de dezembro de 2023. http://dx.doi.org/10.1075/babel.00367.hua.

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Abstract Within a multimodal framework, this study investigates the images of Zhuangzi (author of the Chinese Classic 莊子 Zhuangzi) represented by the front covers of both the comic adaptation 莊子説 Zhuangzi Shuo and its three translations. It is found these covers represent different images of Zhuangzi through processes of recontextualization. In the Chinese adaptation Zhuangzi Shuo, Zhuangzi, while being emphasized as a revered ancient Chinese philosopher, is remolded from an author into a funny speaker absorbed in expressing his thoughts regardless of whether there is any audience. In Zhuangzi Speaks, an English translation published in America, Zhuangzi is repackaged as a friendly interlocutor sharing with readers his thoughts. In The Sayings of Zhuang Zi, another English translation published in Singapore, Zhuangzi is reshaped as a historical figure for detached observation, one frustrated by chaos in reality and investing his thought into his writing. In Lehrsprüche des Dschuang Dsi, a German translation translated indirectly from the Singaporean one, Zhuangzi, while being a historical figure for detached observation as well, is re-reshaped as a reputable Chinese sage, who is old-fashioned but accessible. Differences in these images can be ascribed to diverse perceptions of comics and Zhuangzi in the countries concerned.
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Beebe, Signe. "Qi Ju Di Huang Wan (Lycium Fruit, Chrysanthemum and Rehmannia Pill)". American Journal of Traditional Chinese Veterinary Medicine 16, n.º 1 (1 de fevereiro de 2021). http://dx.doi.org/10.59565/bdhh8837.

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Qi Ju Di Huang Wan (Lycium Fruit, Chrysanthemum and Rehmannia Pill) nourishes Liver and Kidney Yin. This formula has similar actions as Liu Wei Di Huang Wan (Six-Ingredient Pill with Rehmannia) to tonify Yin, however, it has a stronger ability to nourish Liver Yin and treat visual disorders. The original source of Qi Ju Di Huang Wan is from the Yi Ji (Levels of Medicine). Qi Ju Di Huang Wan is composed of the same six herbs as Liu Wei Di Huang Wan (Six-Ingredient Pill with Rehmannia). Shu Di Huang (Rehmannia), the chief herb, tonifies Kidney Yin and Jing (Essence) and fills the marrow. Shan Zhu Yu (Cornus) nourishes the Liver and Kidney and astringes Jing. Shan Yao (Dioscorea) tonifies the Spleen, Kidney and consolidates Jing. Together, these three tonic herbs address deficiencies in the Kidney, Liver and Spleen. Ze Xie (Alisma) sedates the Kidney, causes turbidity to descend, and controls the stagnating effect of Shu Di Huang (Rehmannia). Mu Dan Pi (Cortex Moutan) sedates Deficiency Fire of the Liver, as well as balances the astringent property of Shan Zhu Yu (Cornus). Fu Ling (Poria) strengthens the Spleen, resolves Dampness and balances Shan Yao (Dioscorea). In addition, it contains two herbs Gou Qi Zi (Fructus Lycii) and Ju Hua (Flos Chrysanthemi), that function to improve vision and treat various ocular disorders.
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Ohgata, Tohru. "Interpretations of the term Fu Yao (扶揺) in the Zhuang Zi outer chapter Zaiyou (在宥) and Guo Xiang Zhu (郭象注): Issues concerning the commentator approach". Journal of Chinese Writing Systems, 24 de julho de 2022, 251385022211039. http://dx.doi.org/10.1177/25138502221103903.

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The 10 suns bathing relates to sun worship. The story of the suns bathing and then emerging from the water has likely become one of a fish changing into a bird, becoming a winged sun, and then flying off from the tree branches. When icons and documents such as Chu Ci (楚辞), the Chu (楚) silk paintings, Shan Hai Jing (山海經), and the Mawangdui (馬王堆) silk paintings are brought together, this outline can be drawn. In doing so, the “ Fu Yao (扶揺)” is not the “wind” in Guo Xiang’s (郭象) annotation; it is best to understand the “ Fu Yao (扶揺)” in Xiaoyaoyou (逍遙遊) and the “ Fu Yao (扶揺) branches” in the Zaiyou (在宥) text to both be akin to “ Fusang (扶桑).”
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Jiang, Meiting, Xiaohang Li, Yuying Zhao, Yadan Zou, Maoli Bai, Zhiming Yang, Wei Wang et al. "Characterization of ginsenosides from Panax japonicus var. major (Zhu-Zi-Shen) based on ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry and desorption electrospray ionization-mass spectrometry imaging". Chinese Medicine 18, n.º 1 (8 de setembro de 2023). http://dx.doi.org/10.1186/s13020-023-00830-9.

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Abstract Background Panax japonicus var. major (PJM) belongs to the well-known ginseng species used in west China for hundreds of years, which has the effects of lung tonifying and yin nourishing, and exerts the analgesic, antitussive, and hemostatic activities. Compared with the other Panax species, the chemical composition and the spatial tissue distribution of the bioactive ginsenosides in PJM have seldom been investigated. Methods Ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UHPLC/QTOF-MS) and desorption electrospray ionization-mass spectrometry imaging (DESI-MSI) were integrated for the systematic characterization and spatial tissue distribution studies of ginsenosides in the rhizome of PJM. Considering the great difficulty in exposing the minor saponins, apart from the conventional Auto MS/MS (M1), two different precursor ions list-including data-dependent acquisition (PIL-DDA) approaches, involving the direct input of an in-house library containing 579 known ginsenosides (M2) and the inclusion of the target precursors screened from the MS1 data by mass defect filtering (M3), were developed. The in situ spatial distribution of various ginsenosides in PJM was profiled based on DESI-MSI with a mass range of m/z 100–1500 in the negative ion mode, with the imaging data processed by the High Definition Imaging (HDI) software. Results Under the optimized condition, 272 ginsenosides were identified or tentatively characterized, and 138 thereof were possibly not ever reported from the Panax genus. They were composed by 75 oleanolic acid type, 22 protopanaxadiol type, 52 protopanaxatriol type, 16 octillol type, 19 malonylated, 35 C-17 side-chain varied, and 53 others. In addition, the DESI-MSI experiment unveiled the differentiated distribution of saponins, but the main location in the cork layer and phloem of the rhizome. The abundance of the oleanolic acid ginsenosides was high in the rhizome slice of PJM, which was consistent with the results obtained by UHPLC/QTOF-MS. Conclusion Comprehensive characterization of the ginsenosides in the rhizome of PJM was achieved, with a large amount of unknown structures unveiled primarily. We, for the first time, reported the spatial tissue distribution of different subtypes of ginsenosides in the rhizome slice of PJM. These results can benefit the quality control and further development of PJM and the other ginseng species.
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"Observatoire de Zi-Ka-Wei. Etude sur la pluie en Chine. Par le P. E. Gherzi, S.J. I ptie, Les Résultats, II ptie, Les Observations. Atlas, Distribution des pluies en Chine par mois, saisons, année. 3 vols. Chang-Hai (Imprimerie de la Mission Catholique)",. Quarterly Journal of the Royal Meteorological Society 55, n.º 229 (10 de setembro de 2007): 89–90. http://dx.doi.org/10.1002/qj.49705522915.

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