Artigos de revistas sobre o tema "Yizkor"

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1

Wolf, Jeffrey. "Yizkor Season". Prairie Schooner 97, n.º 1 (março de 2023): 157–58. http://dx.doi.org/10.1353/psg.2023.a920321.

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Ron, Zvi. "Walking Out for Yizkor". Zutot 14, n.º 1 (9 de novembro de 2017): 32–48. http://dx.doi.org/10.1163/18750214-12341286.

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Abstract In many synagogues it is customary for people with living parents to walk out of the sanctuary for the Yizkor memorial service. This has been explained in many ways, with most explanations involving the evil eye or liturgical concerns. This article examines the origin of the Yizkor service and its connection to the collection of monetary donations in honor of the deceased. This practice, connecting Yizkor with donations, is proposed as a significant factor that those with living parents would not participate in this service.
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3

LUPU, DALE. "Yizkor Minyan: Memorial Suite". Palliative and Supportive Care 2, n.º 1 (março de 2004): 91–93. http://dx.doi.org/10.1017/s147895150404012x.

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4

Jones, Faith, e Gretta Siegel. "Yizkor books as Holocaust grey literature". Publishing Research Quarterly 22, n.º 1 (março de 2006): 52–62. http://dx.doi.org/10.1007/s12109-006-0008-2.

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5

Pinto Taylor, Emily. "Yizkor for a student of Freud". Chest 150, n.º 2 (agosto de 2016): 465–66. http://dx.doi.org/10.1016/j.chest.2016.03.006.

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Moreno, Aviad, e Haim Bitton. "The Moroccan “Yizkor Book”: Holocaust Memory, Intra-Jewish Marginalization, and Communal Empowerment in Israel". Diaspora: A Journal of Transnational Studies 23, n.º 2 (1 de setembro de 2023): 261–83. http://dx.doi.org/10.3138/diaspora.23.2.2023.08.09.

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The writing of “Yizkor books” (Yizker bikher, רעכיב רוכזי)—memorial books for European Jewish communities that were destroyed in the Holocaust—has developed and expanded as the remnants of these lost communities scattered around the globe in the post-war era. The motives for writing comparable books among non-European Jewish communities—which experienced different circumstances of dispersal but were still influenced by Holocaust memory—and the way these books nourished the intentional creation of immigrant communities, are understudied. This article focuses on the related genre of what we define as community-oriented autobiographical memoirs penned by Moroccan Jews who migrated to Israel in the 1950s. Within these books, we trace patterns of narration and memory construction utilized by Moroccan leaders in an effort to cope with the stereotyping and exclusion of their communities from mainstream culture by the Ashkenazi-European elite in Israel. We explore how these narratives by Moroccan immigrants were, on the one hand, inspired by commonplace Israeli Holocaust memories depicting the traumatic annihilation of Jewish life in Morocco, and, on the other hand, accounts of Moroccan marginality in Israel.
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Young, James E. "Écrire le monument: site, mémoire, critique". Annales. Histoire, Sciences Sociales 48, n.º 3 (junho de 1993): 729–43. http://dx.doi.org/10.3406/ahess.1993.279169.

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En accord avec le côté livresque et iconoclaste de la tradition juive, les premiers « mémoriaux » consacrés à l'Holocauste ne vinrent pas s'inscrire dans la pierre, le verre, ni l'acier, mais dans des récits. Les Yizkor Bûcher — livres du souvenir— racontaient à la fois la vie et la destruction des communautés juives européennes, en usant du moyen de commémoration le plus ancien chez les Juifs, le livre. Comme l'indique la préface de l'un de ces ouvrages : « Chaque fois que nous prendrons ce livre nous aurons le sentiment de nous trouver devant la tombe [des victimes] car même cela leur a été refusé par les assassins ». Les scribes des shtetls espéraient que la lecture des Yizkor Bicher transformerait le lieu de lecture en espace commémoratif. En réponse à ce que l'on a appelé le « syndrome de la tombe absente », les premiers lieux de mémoire créés par les survivants furent donc des espaces intérieurs, des cimetières imaginaires.
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Riegel, Christian. "Mourning, Memorial, and the Yizkor Books in Eli Mandel's Out of Place". Mosaic: an interdisciplinary critical journal 50, n.º 2 (2017): 187–204. http://dx.doi.org/10.1353/mos.2017.a663697.

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Amir, Michlean, e Rosemary Horowitz. "Yizkor Books in the Twenty-First Century: A History and Guide to the Genre". Judaica Librarianship 14, n.º 1 (31 de dezembro de 2008): 39–56. http://dx.doi.org/10.14263/2330-2976.1073.

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10

Jablon, Rachel Leah. "Witnessing as Shivah; Memoir as Yizkor: The Formulation of Holocaust Survivor Literature as Gemilut Khasadim". Journal of Popular Culture 38, n.º 2 (novembro de 2004): 306–24. http://dx.doi.org/10.1111/j.0022-3840.2004.00114.x.

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Vasvári, Louise O. "Culinary Nostalgia and Post-Traumatic Stress Disorder: Addenda to Kinga Király's Az újrakezdés receptjei (2019) / Recipes for a New Beginning (2020)". Hungarian Cultural Studies 14 (16 de julho de 2021): 186–204. http://dx.doi.org/10.5195/ahea.2021.437.

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Kinga Király conducted interviews with ten North Transylvanian survivors who represent the last witnesses of a generation that is about to disappear and leave us with the question of what to remember and how. On reading the testimonies catalogued in the volume Király produced from those interviews, I realized that I felt compelled to make further connections with my own research on foodways and war trauma and on the ecologies of survival witnessing. In a section on the mass genocide of Transylvanian Jewry I provide a brief historical sketch to help the understanding of the historical complexity and tragedy of the lives of pre- and postwar Transylvanian Jewry. I then contrast the stories of some of Király's subjects with the postwar memoirs of other Transylvanian survivors who emigrated either right after the war or under the Ceausescu dictatorship. I discuss prewar Transylvanian Jewish food culture, and subsequently locate Király's collection as a continuation of the tradition of the memorial or yizkor [‘remembrance’] books. Finally, I discuss Jewish cemeteries and the virtual social death of Jewish tradition in Transylvania, to ask: what is it that remains today from the shattered culture of Transylvanian Jewry?
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12

Rubin, Simon Shimshon. "Loss and Mourning in the Jewish Tradition". OMEGA - Journal of Death and Dying 70, n.º 1 (novembro de 2014): 79–98. http://dx.doi.org/10.2190/om.70.1.h.

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Robert Kastenbaum was a man who helped reintroduce issues related to death, dying, and bereavement to academic, clinical, and general discourse. This article, devoted to an encounter with the observance of mourning custom and ritual in the Jewish tradition, continues the dialogue in this journal that Bob founded. The article utilizes the Two-Track Model of Bereavement to address the Jewish tradition's structuring of the loss experience. After a brief introduction, I present a schematic presentation of some of the issues operant in grief and mourning for the believer. This is followed by two responses to loss that portray the pain of loss in the tradition. The article goes on to consider the Jewish time cycle of response to loss—from preburial Aninut, to Shiva, the first week, to Shloshim, the first month, to Shanah, the first year, to the expectations for encounters across the life cycle. The Yizkor and Kaddish are also considered. In the Jewish tradition, alongside attention to what level of functioning to require of the bereaved, there are lifelong opportunities to rework and maintain connection to the memories, associations, narratives, and experiences that comprise the psychological organization of the continuing bond and relationship to the deceased.
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13

Rich, Jennifer. "Let this Book be a Monument: Yizker Bikher and Jewish Collective Memory". Diaspora: A Journal of Transnational Studies 23, n.º 2 (1 de setembro de 2023): 183–99. http://dx.doi.org/10.3138/diaspora.23.2.2023.07.07.

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In the immediate aftermath of the Holocaust, Eastern European Jews turned to a rich tradition of remembering lost peoples and cultures, and organized the collaborative writing of memorial books. There were over 1,000 of these place-based memory texts written by survivors and pre-war emigres in order to shape knowledge about the war, to emphasize the vibrancy of their prewar lives, and to share their memories and perceptions with future generations. This corpus of material has been largely overlooked by scholars over the past seventy years; this article begins to fill the gap in what is known about postwar memorial books.
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14

Modisane, Litheko. "Yizo Yizo: sowing debate, reaping controversy". Social Dynamics 36, n.º 1 (março de 2010): 122–34. http://dx.doi.org/10.1080/02533950903561353.

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15

Tzur, Dvir. "Strolling in Tel Aviv: Setting Up and Breaking Down Boundaries in S. Yizhar'sPreliminaries(Mikdamot)". AJS Review 41, n.º 1 (abril de 2017): 67–88. http://dx.doi.org/10.1017/s0364009417000046.

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The article discusses the image of Tel Aviv, the first Hebrew city, as it is described in the novelPreliminariesby S. Yizhar (Yizhar Smilansky), one of Israel's best-known authors. In this novel, which engages with the question of home and borders, borders function as a double-edged sword: on the one hand, they define home and create a circumscribed place for the protagonist and his family. On the other hand, the novel dwells on the urge to cross borders and shatter the distinction between home and the world. In this regard, Tel Aviv is sometimes described as a pleasant, “normal” city, yet at other times it is written as a perilous place—since it divides between Jews and Arabs. Tel Aviv is also the place where one can imagine a great future or see a concealed history. It is a total urban experience, encapsulating the individual.
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16

Stieglitz, Robert R. "The Roman Baths of Hammat Gader. Yizhar Hirschfeld." Near Eastern Archaeology 62, n.º 1 (março de 1999): 56. http://dx.doi.org/10.2307/3210725.

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17

Roller, Duane W. "Qumran in Context: Reassessing the Archaeological Evidence. Yizhar Hirschfeld." Bulletin of the American Schools of Oriental Research 340 (novembro de 2005): 94–95. http://dx.doi.org/10.1086/basor25066923.

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18

Barnett, Clive. "Yizo Yizo: Citizenship, Commodification and Popular Culture in South Africa". Media, Culture & Society 26, n.º 2 (março de 2004): 251–71. http://dx.doi.org/10.1177/0163443704041175.

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19

Berlin, Andrea M. "The Roman Baths of Hammat Gader: Final Report. Yizhar Hirschfeld." Bulletin of the American Schools of Oriental Research 314 (maio de 1999): 85–86. http://dx.doi.org/10.2307/1357458.

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20

Schick, Robert. "The Judean Desert Monasteries in the Byzantine Period. Yizhar Hirschfeld". Journal of Near Eastern Studies 58, n.º 1 (janeiro de 1999): 65–66. http://dx.doi.org/10.1086/468677.

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21

Longstaff, Thomas R. W. "Qumran in Context: Reassessing the Archaeological Evidence - By Yizhar Hirschfeld". Religious Studies Review 32, n.º 1 (janeiro de 2006): 42. http://dx.doi.org/10.1111/j.1748-0922.2006.00034_18.x.

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22

Piterberg, Gabriel. "Literature of Settler Societies: Albert Camus, S. Yizhar and Amos OZ". Settler Colonial Studies 1, n.º 2 (janeiro de 2011): 1–52. http://dx.doi.org/10.1080/2201473x.2011.10648811.

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23

Huang, Yizhou. "Radical Hope". Theater 54, n.º 2 (1 de maio de 2024): 31–49. http://dx.doi.org/10.1215/01610775-11127570.

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In this article, Yizhou Huang considers the transnational transmission of devised theater, focusing on the Shanghai-based performance group Grass Stage (Caotaiban) led by Zhao Chuan. She discusses the group’s devising process from two symbiotic aspects, the corporeal and the political. Attending to Grass Stage’s eclectic inspirations and international collaborations, Huang compares the collective to world renowned ensembles such as Théâtre du Soleil and parses out the unequal transactions between Asian performance traditions and devised theater techniques. She warns against a neo-Orientalism that positions non-Western artists and their works solely into an epistemological framework that applauds liberal democracy and argues for devised theater as a site of minor interventions, world making, as well as radical hope.
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24

Ben-Dov, Nitza. "An Epic of Birth, Survival, and Growth: Preliminaries, by S. Yizhar". Hebrew Studies 52, n.º 1 (2011): 293–314. http://dx.doi.org/10.1353/hbr.2011.0012.

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Guo, Ying, Tian He, Ping Nie e Ru Zhang. "Construction of Language Landscape in Newly Built Ancient Cities: A Case of Yizhou Ancient City, China". Journal of Contemporary Language Research 2, n.º 4 (25 de dezembro de 2023): 199–206. http://dx.doi.org/10.58803/jclr.v2i4.85.

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Introduction: As China has increasingly ushered in the era of mass tourism, ancient city or town tourism has gained popularity across the country, and a significant number of new scenic spots in ancient towns have been constructed. However, these lovely spots typically rely on conventional tourist and catering. Many tourists focus more on the issue of how to study old cities’ cultural ambiance and internal features on a deeper level, as well as the depth of its connotations. This paper examined the language landscape creation of the Yizhou Ancient City in Linyi, China, to delve into the language landscape building of newly built ancient town tourist attractions. Methodology: The data collection stage was mainly completed through field investigation, using digital cameras to shoot various language signs in the scenic spot. The data statistics stage mainly included random interviews, research objective determination, and data statistical analysis. Results: The results showed that the language signs in the scenic spot were mainly monolingual, supplemented by bilingual signs. There were two languages, Chinese and English, in which Chinese was the priority code, while English was a marginalized code in the language landscape of the scenic spot. The management department of scenic spots played a decisive role in constructing language landscapes. However, the managers of scenic spots and shop operators had not yet realized the economic value of language landscapes. The language landscape of Yizhou ancient City has the following problems: insufficient construction of a diversified language landscape, weak design sense of language landscape, lack of cultural connotation of language landscape, lack of innovation of language landscape construction and so on. Conclusion: It is suggested that the scenic spot management department should pay attention to different aspects in the future. They should pay attention to the potential value of language landscape construction, the unique linguistic landscape brand of the scenic spot should be constructed, and the multi-language needs of tourists.
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宁, 浩禹. "Some Problems in the History of Yizhou Governor in Tang Dynasty (630~780 Years)". Open Journal of Historical Studies 12, n.º 02 (2024): 107–13. http://dx.doi.org/10.12677/ojhs.2024.122017.

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Li, Xiao-Dong, Zhen-xing Ma, Wan-Tao Rong, Di Xu e Ran Li. "The complete mitochondrial genome of Polygonia c-aureum (Lepidoptera: Nymphalidae) from Yizhou of China and its phylogeny". Mitochondrial DNA Part B 5, n.º 3 (2 de julho de 2020): 2918–19. http://dx.doi.org/10.1080/23802359.2020.1791759.

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Arav, Rami. "Yizhar Hirschfeld. Qumran in Context, Reassessing the Archaeological Evidence. Peabody, MA: Henderson Publishers, 2004. 220 pp; 136 figures." AJS Review 29, n.º 2 (novembro de 2005): 373–76. http://dx.doi.org/10.1017/s0364009405280170.

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About 35,000 books and articles have been published thus far on the Dead Sea Scrolls (DSS). The vast majority deal with the literature found in the eleven caves in the vicinity of Qumran and only a few deal with the archaeological remains of Khirbet Qumran nearby. The site was exhaustively excavated a few times in the past fifty-four years. The first that also determined the nature of its interpretation was carried out during 1951 to 1956 by Fr. Roland de Vaux from the French school of biblical studies at Jerusalem, the Ecole Biblique. Most of the site was unearthed during this excavation. The latest excavations were carried out in the past ten years and thus far with extremely meager publications.
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孟, 鲁. "Investigation on the Development of Self-Consciousness among Primary School Students from Grade 4 to 6 in Yizhou". Advances in Social Sciences 09, n.º 03 (2020): 269–74. http://dx.doi.org/10.12677/ass.2020.93041.

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黄, 慧琳. "Comparison of Leaf Surface Microstructure and Dust Retention Capacity of Common Greening Tree Species in Yizhou Urban Area". Advances in Environmental Protection 13, n.º 04 (2023): 952–70. http://dx.doi.org/10.12677/aep.2023.134117.

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Magness, Jodi. "The Early Byzantine Monastery at Khirbet ed-Deir in the Judean Desert: The Excavations in 1981-1987. Yizhar Hirschfeld." Bulletin of the American Schools of Oriental Research 322 (maio de 2001): 91–94. http://dx.doi.org/10.2307/1357524.

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Hamdan, Mohammed. "‘The orange was dried up and shriveled’: oranges and the crisis of nationalism in Ghassan Kanafani and Smilansky Yizhar". National Identities 20, n.º 3 (12 de janeiro de 2017): 321–36. http://dx.doi.org/10.1080/14608944.2016.1256981.

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Li, Meisong, e Xuanxuan Tian. "Preliminary Exploration on the Application of 5G+VR/AR Scenario in Teaching - Taking the Lesson “Crossing the Currency Town” of Financial Literacy Education as an Example". Science Insights Education Frontiers 15, S1 (31 de março de 2023): 11. http://dx.doi.org/10.15354/sief.23.s1.ab011.

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The application of 5G technology in education is a major challenge in creating a new teaching ecosystem. The use of 5G+VR/AR scenarios in teaching is still in the theoretical exploration stage, lacking practical cases for education. This paper discusses the practical thinking of 5G+VR/AR scene intelligent teaching, providing cases of 5G+VR/AR classroom application to promote intelligent teaching in the direction of visualization, intelligence and scenario-based learning. Yizhou Primary School developed a curriculum resource “Crossing the Currency Town” that combines financial literacy teaching with 5G+VR/AR scenarios. The school built a 5G+VR smart cloud classroom based on the 5G network and VR/AR intelligent devices, educational terminals, and network devices to create an immersive and real-time teaching scene. The implementation of intelligent teaching requires the construction of an intelligent environment through the use of intelligent technology to improve the learners’ classroom experience and realize the interaction and cooperation between teachers, students, and machines. Intelligent equipment can also conduct multiple evaluations and monitor students’ learning effects in real-time, generating accurate analysis reports of the learning situation. The data collected can provide resources for personalized recommendation of intelligent teaching and generate intelligent and personalized learning programs.
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Stampfer, Shaul. "Memorial Books of Eastern European Jewry: Essays on the History and Meanings of Yizker Volumes. By Rosemary Horowitz . Jefferson, NC: McFarland & Company, Inc., 2011. Pp. vi + 296, plates. Paper, $55.00." Religious Studies Review 38, n.º 4 (dezembro de 2012): 251. http://dx.doi.org/10.1111/j.1748-0922.2012.01657_6.x.

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Amit Assis. "“His Ancestors Were Calling Him Back to His Origins”: Zionism and the Poetics of Space in the Early Work of S. Yizhar". Prooftexts 36, n.º 3 (2018): 383. http://dx.doi.org/10.2979/prooftexts.36.3.07.

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Zhao, Q. "Construction in Contradiction: A Multiple-insight into Relationships between China and Key International Organizations. Wang Yizhou (ed.). Beijing: Development Press, 2003, 358 pp". International Relations of the Asia-Pacific 4, n.º 1 (1 de fevereiro de 2004): 202–4. http://dx.doi.org/10.1093/irap/4.1.202.

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Bayley, James C. "LUMBOSACRAL AND SPINOPELVIC FIXATION. Joseph Y. Margulies, Yizhar Floman, Jean-Pierre C. Farcy, and Michael G. Neuwirth. Philadelphia, Lippincott-Raven, 1996. $195.00, 928 pp." Journal of Bone & Joint Surgery 79, n.º 2 (fevereiro de 1997): 317. http://dx.doi.org/10.2106/00004623-199702000-00021.

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Anam. "Casting off the Shackles: Re-narrativizing Discrepant Terrains of Memories with Lived Experiences in A. B. Yehoshua’s Facing the Forests". Contemporary Review of the Middle East 5, n.º 4 (21 de setembro de 2018): 294–307. http://dx.doi.org/10.1177/2347798918795366.

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The ever-increasing human migration with fast-eroding bonds often leads to development of social clusters which tend to produce stereotypes about other groups of people. One among the many factors responsible for such ghettoization is not ignorance but a version of knowledge that does not take us beyond ourselves. Speaking about the role of writer as “the conscience of the nation,” S. Yizhar, an Israeli writer and politician, says that a writer is a mutation. Literature is one such powerful tool to transcend cultural boundaries which takes us beyond ourselves and reaches to the other side. Holding the case of Israeli–Palestinian contestation as one such manifestation of cultural ghettoization, the article argues for the need to render open the mental borders to move beyond prejudices. Taking A. B. Yehoshua’s Facing the Forests as a point of departure, it highlights the potential of dialog as a powerful antidote to social violence between the two communities of Arabs and Israelis and lays bare its importance in the direction of peaceful coexistence. The article is divided into three sections; the first section introduces the cultural location of Yehoshua and his narrative set in the Israeli landscape of the 1960s. The second section explores the use of symbolism in the narrative to cull out the dormant meanings and analyzes the multiple layers of the text. The third and last section projects the idea of re-narrativization as an important tool of re-inscribing history with alternative versions. It draws strength from those Arab–Jewish encounters that are not necessarily troubling. The conclusion sums up the essential findings of the study, elucidating the role of literature and intellectuals in difficult times.
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Lee, Hayan, Gat Krieger, Tyson Clark, Yizhou Zhu, Aziz Khan, Casey R. Hanson, Aaron Horning et al. "Abstract 4742: Familial adenomatous polyposis epigenetic landscape as a precancer model of colorectal cancer". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 4742. http://dx.doi.org/10.1158/1538-7445.am2023-4742.

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Abstract Aberrant shifts in DNA methylation have long been regarded as an early biomarker for cancer onset and progression. However, it is unclear when methylation aberrance starts and how it interacts with other epigenomic modifications. To address how epigenomic changes occur and interact during the transformation from normal healthy colon tissue to malignant colorectal cancer (CRC), we collected 51 samples from 15 familial adenomatous polyposis (FAP) and non-FAP colorectal cancer patients. We generated 30-70x of whole-genome enzymatic methylation sequencing (WGEM-seq) data via the novel Ultima Genomics ultra high-throughput sequencing platform. We observed hypermethylation and hypomethylation emerge early in the malignant transformation process in gene promoters and distal regulatory elements. We performed multifaceted analysis on methylation alterations with whole-genome sequencing (WGS), transposase accessibility (ATAC-seq), high-resolution chromatin accessibility (Tri-C), and gene expression (RNA-seq) data. Our multidimensional analysis demonstrates how collectively epigenomic alterations have affected gene expression throughout normal colon mucosa, benign and dysplasia polyps to adenocarcinoma. Epigenomic changes start as early as benign polyps, followed by other epigenomic shifts, including bivalent domains. Various epigenomic aberrances are associated with concomitant gene expression level changes. Our integrative analysis of multi-epigenomics data implicates collective and cumulative epigenomic instability in the early onset of colon carcinogenesis. Citation Format: Hayan Lee, Gat Krieger, Tyson Clark, Yizhou Zhu, Aziz Khan, Casey R. Hanson, Aaron Horning, Edward D. Esplin, Mohan Badu, Kristina Paul, Roxanne Chiu, Bahareh Bahmani, Stephanie Nevins, Annika K. Weimer, Ariel Jaimovich, Christina Curtis, William Greenleaf, James M. Ford, Doron Lipson, Zohar Shipony, Michael P. Snyder. Familial adenomatous polyposis epigenetic landscape as a precancer model of colorectal cancer. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 4742.
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Kou, Yanfei, Sanming Chen, Kefa Zhou, Ziyun Qiu, Jiaming He, Xian Shi, Xiaozhen Zhou e Qing Zhang. "Spatiotemporal Patterns and Coupling Coordination Analysis of Multiscale Social–Economic–Ecological Effects in Ecologically Vulnerable Areas Based on Multi-Source Data: A Case Study of the Tuha Region, Xinjiang Province". Land 13, n.º 3 (24 de fevereiro de 2024): 282. http://dx.doi.org/10.3390/land13030282.

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Ecologically fragile areas are confronted with the contradiction between economic development and ecological protection, especially in the Tuha region (Turpan and Hami), where the extremely vulnerable ecological environment limits local sustainable development. To address this, this study utilizes POI (Point of Interest) data, land use, and socioeconomic statistical data to achieve spatial quantification of indicators on a kilometer grid scale, constructing a multi-factor, multi-dimensional evaluation system for the socioeconomic and ecological effects of sustainable development based on SDGs (Sustainable Development Goals). The entropy method, comprehensive evaluation method, coupling coordination degree model, and geographical detector method are used to analyze the coupling relationships between systems at different scales and the factors influencing the system’s coupling coordination degree. The results indicate that from 2010 to 2020, the economic, social, and ecological systems of the Tuha region, as well as their comprehensive scores, exhibited spatial similarity. The economic system showed an upward trend, the social system displayed an inverted U-shaped trend of rising then declining, while the ecological system presented a U-shaped trend of declining then increasing. At the county scale, the coupling coordination degree closely approximates the trend of the comprehensive coordination index, showing a continuous upward trajectory. Compared with Turpan city, Hami city, especially Yizhou district, exhibits the best development in coupling coordination degree, while the growth in coupling coordination degree is most significant in Gaochang district. The main factors influencing the degree of coupling coordination are grain production and GDP (gross domestic product). This study provides a new perspective on the quantification of sustainable development indicators, which is of great significance for balancing economic and social development with ecological protection and promoting the coupled and coordinated development of society, economy, and ecology in ecologically fragile areas.
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Jiang, Yanyan, Hala Estephan, Yizhou Wang, Ftoon Aljarbou, Nuria V. Lopera, Eui Jung Moon, Ester M. Hammond e Amato J. Giaccia. "Abstract 3273: Tirapazamine sensitizes homologous recombination-proficient cancers by enhancing DNA damage andferroptosis". Cancer Research 84, n.º 6_Supplement (22 de março de 2024): 3273. http://dx.doi.org/10.1158/1538-7445.am2024-3273.

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Abstract Despite its success in HR-deficient tumors, the application of PARP inhibitors (PARPis) in HR-proficient cancers is very limited. Since the majority of cancers are HR-proficient, there is a need for developing strategies to extend the use of PARPis to HR-proficient cancers. We investigated whether the hypoxic cytotoxin, tirapazamine (TPZ) sensitizes HR-proficient cancer cells to PARPis under normoxia and hypoxia (2% O2), and found that TPZ enhanced PARPi cell killing to a greater extent under hypoxia compared to normoxia. Mechanistically, this enhanced killing was due to the induction of DNA double-strand breaks and free radicals that lead to ferroptotic cell death. To determine the role of hypoxia in the anti-tumor effect of the combination treatment, we examined the efficacy of TPZ and PARPi treatment in hypoxic spheroids and subcutaneous xenograft models derived from a panel of HR-proficient human non-small cell lung cancer (NSCLC) cells. We found that PARPis combined with TPZ significantly inhibited the growth of the hypoxic NSCLC spheroids. In addition, the combination treatment significantly inhibited the growth of A549 and CORL105 xenografts that possess significant hypoxic fractions, but did not significantly inhibit the growth of well-oxygenated Calu3 and H3122 xenografts. Taken together, this study demonstrates that TPZ can sensitize HR-proficient tumor cells to PARPi through the introduction of DNA strand breaks and free radicals, suggesting that TPZ treatment can broaden the usage of PARPi to HR-proficient cancers. Citation Format: Yanyan Jiang, Hala Estephan, Yizhou Wang, Ftoon Aljarbou, Nuria V. Lopera, Eui Jung Moon, Ester M. Hammond, Amato J. Giaccia. Tirapazamine sensitizes homologous recombination-proficient cancers by enhancing DNA damage andferroptosis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 3273.
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Ben-Dov, Nitza. "My Imaginary Offspring: Reality and Fantasy in Days of Ziklag by S. Yizhar and in If There is a Heaven by Ron Leshem". Hebrew Studies 50, n.º 1 (2009): 185–94. http://dx.doi.org/10.1353/hbr.2009.0002.

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Pitout, Magriet, e Musa Ndlovu. "The South African Broadcasting Corporation (SABC) and the social responsibility media theory: the case ofYizo Yizo". Communicatio 27, n.º 2 (janeiro de 2001): 19–28. http://dx.doi.org/10.1080/02500160108537903.

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Mhlambi, Innocentia Jabulisile. "“It is not crime in the way you see it”: Crime discourses and outlaw culture inYizo Yizo". Current Writing 22, n.º 2 (janeiro de 2010): 152–65. http://dx.doi.org/10.1080/1013929x.2010.9678353.

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Griffith, Sidney H. "Judean Monasteries in the Byzantine Period, by Yizhar Hirschfeld. 305 pages, maps, illustrations, notes, bibliography, index. New Haven: Yale University Press, 1992. $45 (Cloth) ISBN 0-300-04977-3". Middle East Studies Association Bulletin 26, n.º 2 (dezembro de 1992): 265–66. http://dx.doi.org/10.1017/s002631840002633x.

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Barnea, Ofer Yizhar, Ilias Georgakopoulos-Soares, Nadav Ahituv, Jocelyn Chapman, Martin Hemberg, Ioannis Mouratidis, Konstantinos Syrigos et al. "Abstract 991: Leveraging sequences missing from the human genome to detect cancer". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 991. http://dx.doi.org/10.1158/1538-7445.am2023-991.

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Abstract Introduction: Cancer diagnosis using cell-free DNA (cfDNA) has the potential to improve treatment and survival but has several technical limitations. Methods: Here, we used neomers, short DNA sequences (13-17bp in length) that are largely absent from the healthy human genome, but appear in the tumor genome due to somatic mutations, to detect cancer at early stages from cfDNA. cfDNA was extracted from 1mL of plasma, and utilized from Whole Genome Sequencing at 5X coverage. Results: First, we analyzed over 2,500 cancer whole-genome sequences (WGS), to show that a neomer-based classifier can distinguish twenty-one different tumor types with higher accuracy than state-of-the-art methods. Refinement of this classifier via manually selected neomer sets, identified additional cancer features with greater precision. We next generated cfDNA WGS data from >600 patients and non-cancerous controls across four different types of cancers (prostate, lung, ovarian, colorectal), and demonstrated that neomers can precisely identify cancer from a limited amount of plasma for all four cancer types, with exampled sensitivities of 93.73% and 73.47% for lung and ovarian cancers, respectively. Additionally, using both luciferase and massively parallel reporter assays (MPRAs), we show that our neomer-driven approach can detect cancer-associated non-coding mutations that affect gene regulatory activity. Conclusions: Our results show that neomers provide a novel, sensitive, specific and potentially broadly applicable cancer detection tool. This approach has several advantages over existing strategies for liquid biopsies: 1) it is based on standard next-generation sequencing which is already widely available in the clinic; 2) it requires low amounts of starting material and is completely tumor agnostic; 3) it searches the entire genome and is not restricted to known driver mutations. 4) it allows the detection of early-stage disease. Citation Format: Ofer Yizhar Barnea, Ilias Georgakopoulos-Soares, Nadav Ahituv, Jocelyn Chapman, Martin Hemberg, Ioannis Mouratidis, Konstantinos Syrigos, Nikolaos Syrigos, Ioannis Vathiotis, Mayank Mahajan, Emmanouil Panagiotou, Andriani Charpidou, Mark Kvale, Candace S. Chan, Ryder Easterlin. Leveraging sequences missing from the human genome to detect cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 991.
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Kanevskiy, L. M., M. V. Grechikhina, E. G. Kuzmina, T. Yu Mushkarina, A. A. Spelkov, M. A. Streltsova e E. I. Kovalenko. "DISTRIBUTION OF MICA ALLELES IN THE RUSSIAN POPULATION". Medical Immunology (Russia) 21, n.º 5 (13 de dezembro de 2019): 959–64. http://dx.doi.org/10.15789/1563-0625-2019-5-959-964.

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Stress factors, infections, tumor transformation of the cells of organism induce the expression of MICA protein, which is a ligand for the NKG2D receptor of NK and T cells. The interaction of the NKG2D receptor on the surface of the cells of the immune system with MICA results in activation of lymphocytes and elimination of the ligand carrier. The MICA gene has a high level of polymorphism. To date, 87 alleles have been described; their products differ in ability to activate cytotoxic lymphocytes, that can affect the progression of a number of diseases, such as cancer, viral infections, autoimmune diseases. The distribution of MICA alleles in different ethnic groups varies considerably. The analysis of MICA polymorphism in a current ethnos is necessary for revealing the relationships between certain MICA alleles and different diseases. Goal. This work is aimed at studying of the distribution of MICA alleles in Russian population. Materials and methods. Polymorphism of MICA was analyzed according to the procedure proposed by Yizhou Zoe and Peter Stastny. The procedure included: 1) isolation of genomic DNA from whole blood; 2) PCR for amplification of a fragment of the MICA gene; 3) sequencing of the resulting PCR fragments. Analysis of the results of sequencing was carried out using the programs Vector NTI and Chromas Lite. Results. The genotype of the MICA alleles of 119 donors has been determined. Of the 87 MICA alleles described in the literature, 15 were found among the samples studied. The frequencies of MICA alleles were the following: *002 – 19.3%, *004 – 6.7%, *007 – 3.0%, *008 – 35.7%, *009 – 10.1%, *010 – 5.0%, *011 – 3.8%, *012 – 2.1%, *016 – 2.5%, *017 – 3.4% *018 – 5.5%, *019 – 0.4%, *027 – 1.3%, *053 – 0.8%, *068 – 0.4%. The distribution of MICA alleles in Russia was found to be similar to that of European countries. When comparing literary data for different countries of the world, it was found that the differences in the distribution of MICA alleles are expressed mainly between races, and not nations. Conclusions. In this paper, the distribution of MICA alleles in Russian population has been analyzed. It turned out to be very similar to those of other European countries and has a number of significant differences from the ethnoses of the Mongoloid race (Japan, China, Korea). The analysis of the distribution of MICA alleles in the Russian population may be useful for identifying the predisposition of individuals to certain diseases.
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Cui, Zhifen, Furong Huang, Kun Fang, Jingyue Yan, Yufan Zhou, Jeffrey Everitt, Yue Zhao et al. "Abstract 495: Targeting undruggable transcription factor HOXB13 in metastatic prostate cancer by CRISPR/Cas13d-based nanoparticle therapy". Cancer Research 84, n.º 6_Supplement (22 de março de 2024): 495. http://dx.doi.org/10.1158/1538-7445.am2024-495.

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Abstract Background: The oncogenic transcription factor HOXB13, which is highly expressed in castration-resistant prostate cancer (CRPC), has been shown to promote CRPC growth and metastasis. However, HOXB13 is considered untargetable by traditional small-molecule-based drug design. Gene therapy is critical alternative strategy with potential to directly target such traditionally undruggable genes. Methods: Selective cell in organ targeting (SCORT) nanoparticles for precise delivery of nanoparticles to metastatic cancer cells in an organ were constructed and characterized by the NanoAssemblr Spark, Zetasizer Nano ZS, and transmission electron microscopy (TEM); Cas13d mRNA with pseudouridine modification was synthesized using in vitro transcription; Hemi-spleen injection of CRPC cells was performed to build CRPC liver metastatic models; RNA-seq was employed to evaluate off-target effects of Cas13d targeting. Results: By incorporating a prostate cancer-specific E3 aptamer to functionalized lipid-like nanoparticles (FTT5 LNP-E3), we have successfully constructed SCORT nanoparticles that enable preferential delivery of mRNAs to metastatic CRPC cells in the liver, as opposed to various normal cells in the surrounding liver tissue. We demonstrated that Cas13d-pre-gHOXB13 mediates highly effective and specific HOXB13 mRNA knockdown in CRPC cells. Significantly, systemic treatment of SCORT nanoparticles carrying Cas13d-pre-gHOXB13 mRNA decreased HOXB13 expression in the metastatic tumors, inhibited metastasis, and prolonged survival of mice bearing androgen receptor (AR)-positive (AR+) or negative (AR-) tumors. Notably, long term (6 and a half weeks) administration of SCORT nanoparticle-Cas13d-pre-gHOXB13 did not significant alter body weight, hepatic and renal function, chemokines and cytokines, and other factors, effectively highlighting its safety. Conclusions: This study is the first to demonstrate that undruggable oncogenic transcription factors can be targeted using nanoparticle-delivered gene therapy based on CRISPR/Cas13 RNA-targeting. The SCORT-CRISPR/Cas13d system is a highly flexible technology that would impact the larger field of translational science by allowing the design of Cas13d-based, cancer cell-specific delivered nanoparticles targeting other previously-undruggable oncogenic transcription factors in metastatic prostate cancer and other solid tumors. Citation Format: Zhifen Cui, Furong Huang, Kun Fang, Jingyue Yan, Yufan Zhou, Jeffrey Everitt, Yue Zhao, William Hankey, Zhong Chen, Hongyan Wang, Victor X. Jin, Yizhou Dong, Qianben Wang. Targeting undruggable transcription factor HOXB13 in metastatic prostate cancer by CRISPR/Cas13d-based nanoparticle therapy [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 495.
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Jian, Shi. "THE WAY TO THE WHITE TIGER HALL CONFERENCE: EVIDENCE GLEANED FROM THE FORMATION PROCESS OF THE BAIHU TONG". Early China 45 (setembro de 2022): 303–39. http://dx.doi.org/10.1017/eac.2022.16.

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AbstractThe White Tiger Hall conference, held in the fourth year (79 c.e.) of the Jianchu 建初 reign in the Eastern Han, was a significant event in both politics and classical learning during and after that time. As the summary of the conference, composed after its conclusion, the Baihu tong 白虎通 is the main resource for investigating the details of this conference. Clarifying the formation process of the Baihu tong is helpful to elicit information regarding the White Tiger Hall conference from the findings recorded in its text. By tracing the history of the court conferences as an administrative institution and considering the particular nature of manuscript compilation, textual genre formats, and literary circulation during the Han, this paper suggests that the Baihu yizou 白虎議奏 referred to in the sources represents the compilation of the positions of the different debaters during the conference by Chunyu Gong 淳于恭 that was eventually sent to Emperor Zhang 章帝 for his approval; the Baihu tongde lun 白虎通德論 would be the corpus of the final rulings that had already been compiled before the conference ended and then edited by Ban Gu 班固. Later, the Emperor instructed his archivists to compose the Baihu tong by condensing the Baihu tongde lun. According to its formation process, the Baihu tong is the work of a collection of experts, rather than a compilation by a single person. Evidence shows that, although Emperor Zhang could weigh in on the court discussions (chengzhi linjue 稱制臨決), he could not ignore the consensus, nor could he simply mandate that the conference participants agree with him. In this regard, the Baihu tong cannot be considered a synthesis of the court's findings, establishing a single court ideology. Rather, it is best to see the text we have now as evidence of vigorous debates among the conference participants, including the Emperor himself and a range of other officials. In conclusion, the best way to uncover the facts about the White Tiger Hall conference via the Baihu tong is to reverse the process of textual formation, to glean information about the probable historical basis for the disputes recorded in the text.
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Brooks Hedstrom, Darlene L. "The Early Byzantine Monastery of Khirbet ed-Deir in the Judean Desert: The Excavations in 1981-1987. By Yizhar Hirschfeld, R. Barkay, R. Ben-Arieh, R. Calderon, E. Cohen, L. di Segni, L. Habas, and R. Talgam." American Journal of Archaeology 107, n.º 1 (1 de janeiro de 2003): 140–41. http://dx.doi.org/10.1086/ajs40026592.

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