Artigos de revistas sobre o tema "XIAP inhibitors"
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Löder, Sandra, Melanie Fakler, Irmela Jeremias, Klaus-Michael Debatin e Simone Fulda. "XIAP Inhibitors Present a Promising New Strategy to Sensitize Childhood Acute Leukemia Cells for Chemotherapy-Induced Apoptosis." Blood 114, n.º 22 (20 de novembro de 2009): 3791. http://dx.doi.org/10.1182/blood.v114.22.3791.3791.
Texto completo da fonteLoeder, Sandra, Thorsten Zenz, Andrea Schnaiter, Daniel Mertens, Dirk Winkler, Hartmut Döhner, Klaus-Michael Debatin, Stephan Stilgenbauer e Simone Fulda. "A Novel Paradigm to Trigger Apoptosis in Chronic Lymphocytic Leukemia." Blood 114, n.º 22 (20 de novembro de 2009): 731. http://dx.doi.org/10.1182/blood.v114.22.731.731.
Texto completo da fonteFakler, Melanie, Sandra Löder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin e Simone Fulda. "Small Molecule XIAP Inhibitors Cooperate with TRAIL to Trigger Apoptosis in Childhood Acute Leukemia Cells and Overcome Bcl-2-Mediated Resistance". Blood 112, n.º 11 (16 de novembro de 2008): 857. http://dx.doi.org/10.1182/blood.v112.11.857.857.
Texto completo da fonteSchimmer, Aaron D., Marcela Gronda, Zhiliang Wang, Kate Welsh, Clemencia Pinilla, Michael Andreeff, Wendy D. Schober et al. "Small-Molecule XIAP Inhibitors Derepress Downstream Effector Caspases and Induce Apoptosis of Leukemia Cell Lines and Patient Samples." Blood 104, n.º 11 (16 de novembro de 2004): 759. http://dx.doi.org/10.1182/blood.v104.11.759.759.
Texto completo da fonteSchimmer, Aaron D., e Shadi Dalili. "Targeting the IAP Family of Caspase Inhibitors as an Emerging Therapeutic Strategy". Hematology 2005, n.º 1 (1 de janeiro de 2005): 215–19. http://dx.doi.org/10.1182/asheducation-2005.1.215.
Texto completo da fonteSchimmer, Aaron D., e Shadi Dalili. "Targeting the IAP Family of Caspase Inhibitors as an Emerging Therapeutic Strategy". Hematology 2005, n.º 1 (1 de janeiro de 2005): 215–19. http://dx.doi.org/10.1182/asheducation.v2005.1.215.215.
Texto completo da fonteFakler, Melanie, Sandra Loeder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin e Simone Fulda. "Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2–mediated resistance". Blood 113, n.º 8 (19 de fevereiro de 2009): 1710–22. http://dx.doi.org/10.1182/blood-2007-09-114314.
Texto completo da fonteSeno, Saki, Minori Kimura, Yuki Yashiro, Ryutaro Kimura, Kanae Adachi, Aoi Terabayashi, Mio Takahashi et al. "β-Thujaplicin Enhances TRAIL-Induced Apoptosis via the Dual Effects of XIAP Inhibition and Degradation in NCI-H460 Human Lung Cancer Cells". Medicines 8, n.º 6 (2 de junho de 2021): 26. http://dx.doi.org/10.3390/medicines8060026.
Texto completo da fonteCillessen, Saskia A. G. M., John C. Reed, Kate Welsh, Clemencia Pinilla, Richard Houghten, Erik Hooijberg, José Deurhof et al. "Small-molecule XIAP antagonist restores caspase-9–mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells". Blood 111, n.º 1 (1 de janeiro de 2008): 369–75. http://dx.doi.org/10.1182/blood-2007-04-085480.
Texto completo da fonteGaponova, Tatyana, Andrey Misurin, Larisa Mendeleeva, Elena Varlamova, Elena Parovichnikova e Valeryi Savchenko. "Expression of XIAP in Multiple Myeloma Patients". Blood 112, n.º 11 (16 de novembro de 2008): 5118. http://dx.doi.org/10.1182/blood.v112.11.5118.5118.
Texto completo da fontePolykretis, Panagis, Enrico Luchinat, Alessio Bonucci, Andrea Giachetti, Melissa A. Graewert, Dmitri I. Svergun e Lucia Banci. "Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach". IUCrJ 6, n.º 5 (23 de agosto de 2019): 948–57. http://dx.doi.org/10.1107/s205225251901073x.
Texto completo da fonteDing, Dongshen, Liang Hong e Chang Shu. "MicroRNA-5100 Modulates Lung Cancer Cell Proliferation and Apoptosis via Inhibiting X-Linked Inhibitor of Apoptosis Protein (XIAP) Expression". Journal of Biomaterials and Tissue Engineering 11, n.º 10 (1 de outubro de 2021): 2037–43. http://dx.doi.org/10.1166/jbt.2021.2790.
Texto completo da fonteFarag, Marc, Charline Kieffer, Nicolas Guedeney, Anne Sophie Voisin-Chiret e Jana Sopkova-de Oliveira Santos. "Computational Tool to Design Small Synthetic Inhibitors Selective for XIAP-BIR3 Domain". Molecules 28, n.º 13 (30 de junho de 2023): 5155. http://dx.doi.org/10.3390/molecules28135155.
Texto completo da fonteZou, Tongtong, Jaladanki N. Rao, Xin Guo, Lan Liu, Huifang M. Zhang, Eric D. Strauch, Barbara L. Bass e Jian-Ying Wang. "NF-κB-mediated IAP expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion". American Journal of Physiology-Cell Physiology 286, n.º 5 (maio de 2004): C1009—C1018. http://dx.doi.org/10.1152/ajpcell.00480.2003.
Texto completo da fonteCarter, Bing Z., Marcela Gronda, Zhiliang Wang, Kate Welsh, Clemencia Pinilla, Michael Andreeff, Wendy D. Schober et al. "Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells". Blood 105, n.º 10 (15 de maio de 2005): 4043–50. http://dx.doi.org/10.1182/blood-2004-08-3168.
Texto completo da fonteKater, Arnon P., Frank Dicker, Massimo Mangiola, Kate Welsh, John Ostresh, Richard Houghten, John C. Reed, Thomas J. Kipps e Clemencia Pinilla. "Inhibition of XIAP Renders Newly CD40-Activated Chronic Lymphocytic Leukemia Cells Sensitive to Fas (CD95) Mediated Apoptosis." Blood 104, n.º 11 (16 de novembro de 2004): 3474. http://dx.doi.org/10.1182/blood.v104.11.3474.3474.
Texto completo da fonteLeverkus, Martin, Martin R. Sprick, Tina Wachter, Thilo Mengling, Bernd Baumann, Edgar Serfling, Eva-B. Bröcker, Matthias Goebeler, Manfred Neumann e Henning Walczak. "Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation". Molecular and Cellular Biology 23, n.º 3 (1 de fevereiro de 2003): 777–90. http://dx.doi.org/10.1128/mcb.23.3.777-790.2003.
Texto completo da fontePark, Cheol-Min, Chaohong Sun, Edward T. Olejniczak, Alan E. Wilson, Robert P. Meadows, Stephen F. Betz, Steven W. Elmore e Stephen W. Fesik. "Non-peptidic small molecule inhibitors of XIAP". Bioorganic & Medicinal Chemistry Letters 15, n.º 3 (fevereiro de 2005): 771–75. http://dx.doi.org/10.1016/j.bmcl.2004.11.010.
Texto completo da fonteHatton, Olivia, Stacie Lambert, Sheri Krams e Olivia Martinez. "Syk survival signals in Epstein-Barr virus + B cell lymphomas (165.27)". Journal of Immunology 186, n.º 1_Supplement (1 de abril de 2011): 165.27. http://dx.doi.org/10.4049/jimmunol.186.supp.165.27.
Texto completo da fontePrager, Gerald W., Judit Mihaly, Patrick M. Brunner, Yuri Koshelnick, Gunilla Hoyer-Hansen e Bernd R. Binder. "Urokinase mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein". Blood 113, n.º 6 (5 de fevereiro de 2009): 1383–90. http://dx.doi.org/10.1182/blood-2008-06-164210.
Texto completo da fonteHaug, Jessica, Vijay G. Ramakrishnan, Teresa Kimlinger, Timothy Halling, Linda Wellik, S. Vincent Rajkumar e Shaji Kumar. "Significant In Vitro Activity of a Novel Inhibitor of Apoptosis (IAP) Inhibitor LC161 In Multiple Myeloma". Blood 116, n.º 21 (19 de novembro de 2010): 2998. http://dx.doi.org/10.1182/blood.v116.21.2998.2998.
Texto completo da fonteCillessen, Saskia A. G. M., John C. Reed, Clemencia Pinilla, Chris J. L. M. Meijer, Erik Hooijberg, Corine J. Hess, Kitty C. M. Castricum, Pim Kortman, Gert J. Ossenkoppele e Joost J. Oudejans. "Small-Molecule XIAP Antagonist Restores Caspase-9-Mediated Apoptosis in XIAP-Positive Diffuse Large B-Cell Lymphoma Cells." Blood 110, n.º 11 (16 de novembro de 2007): 803. http://dx.doi.org/10.1182/blood.v110.11.803.803.
Texto completo da fonteDenault, Jean-Bernard, Brendan P. Eckelman, Hwain Shin, Cristina Pop e Guy S. Salvesen. "Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)–mediated inhibition of caspase 9". Biochemical Journal 405, n.º 1 (13 de junho de 2007): 11–19. http://dx.doi.org/10.1042/bj20070288.
Texto completo da fonteMohapatra, Subhra, Baoky Chu, Xiuhua Zhao, Jianguo Tao, Eduardo Sotomayor e W. Jack Pledger. "Combined Inhibition of CDK and PI3K/Akt Pathways Induces Apoptosis of Mantle Cell Lymphoma." Blood 110, n.º 11 (16 de novembro de 2007): 1384. http://dx.doi.org/10.1182/blood.v110.11.1384.1384.
Texto completo da fonteHo, Andrew T., Qin H. Li, Hitoshi Okada, Tak W. Mak e Eldad Zacksenhaus. "XIAP Activity Dictates Apaf-1 Dependency for Caspase 9 Activation". Molecular and Cellular Biology 27, n.º 16 (11 de junho de 2007): 5673–85. http://dx.doi.org/10.1128/mcb.00188-07.
Texto completo da fonteLucas, H., P. M. Bartold, A. A. S. S. K. Dharmapatni, C. A. Holding e D. R. Haynes. "Inhibition of Apoptosis in Periodontitis". Journal of Dental Research 89, n.º 1 (30 de novembro de 2009): 29–33. http://dx.doi.org/10.1177/0022034509350708.
Texto completo da fonteHe, Yanjuan, Joan Cain, Lee Ratner e Leon Bernal-Mizrachi. "Targeting xIAP Is More Important Than Bcl-Xl in Lymphomas with Constitutive Activation of NF-kB." Blood 108, n.º 11 (1 de novembro de 2006): 2390. http://dx.doi.org/10.1182/blood.v108.11.2390.2390.
Texto completo da fonteSeca, Hugo, Liliana Santos, Joana Figueiredo, Raquel T. Lima, Jose E. Guimaraes, Clara Sambade e M. Helena Vasconcelos. "Targeting XIAP for Chemosensitization Purposes: Different Effect with Different Cytotoxic Drugs." Blood 112, n.º 11 (16 de novembro de 2008): 1597. http://dx.doi.org/10.1182/blood.v112.11.1597.1597.
Texto completo da fonteKater, Arnon P., Frank Dicker, Massimo Mangiola, Kate Welsh, Richard Houghten, John Ostresh, Adel Nefzi, John C. Reed, Clemencia Pinilla e Thomas J. Kipps. "Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis". Blood 106, n.º 5 (1 de setembro de 2005): 1742–48. http://dx.doi.org/10.1182/blood-2005-02-0695.
Texto completo da fonteLethier, Mathilde, Karine Huard, Michael Hons, Adrien Favier, Bernhard Brutscher, Elisabetta Boeri Erba, Derek W. Abbott, Stephen Cusack e Erika Pellegrini. "Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface". Life Science Alliance 6, n.º 11 (6 de setembro de 2023): e202201784. http://dx.doi.org/10.26508/lsa.202201784.
Texto completo da fonteCarter, Bing Z., Tae Kon Kim, Duncan H. Mak, Wei Hu, Clemencia Pinilla, John C. Reed e Michael Andreeff. "AML Progenitor/Stem Cells Overexpress XIAP and Are Sensitive to the Small Molecular XIAP Inhibitor 1396-11." Blood 108, n.º 11 (16 de novembro de 2006): 2586. http://dx.doi.org/10.1182/blood.v108.11.2586.2586.
Texto completo da fonteCarter, Bing Z., Steven M. Kornblau, Twee Tsao, Rui-Yu Wang, Wendy D. Schober, Michele Milella, Hsi-Guang Sung, John C. Reed e Michael Andreeff. "Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis". Blood 102, n.º 12 (1 de dezembro de 2003): 4179–86. http://dx.doi.org/10.1182/blood-2003-03-0960.
Texto completo da fonteRunckel, Kyle L., Cory Mavis, Joseph Skitzki, Juan J. Gu, Francisco J. Hernandez-Ilizaliturri e Myron S. Czuczman. "Targeting the X-Linked Inhibitor of Apoptosis Protein (XIAP) Can Promote Tumor Cell Death, and Increase the Cytotoxic Effects of Chemotherapy Agents in in Vitro and In Vivo Models of Rituximab-Resistant Lymphoma". Blood 126, n.º 23 (3 de dezembro de 2015): 590. http://dx.doi.org/10.1182/blood.v126.23.590.590.
Texto completo da fonteRajapakse, Hemaka. "Small Molecule Inhibitors of the XIAP Protein-Protein Interaction". Current Topics in Medicinal Chemistry 7, n.º 10 (1 de maio de 2007): 966–71. http://dx.doi.org/10.2174/156802607780906816.
Texto completo da fonteAbbas, Ruqaia, e Sarit Larisch. "Targeting XIAP for Promoting Cancer Cell Death—The Story of ARTS and SMAC". Cells 9, n.º 3 (9 de março de 2020): 663. http://dx.doi.org/10.3390/cells9030663.
Texto completo da fonteKhan, Sumera, Kyle Runckel, Cory Mavis, Matthew J. Barth e Francisco J. Hernandez-Ilizaliturri. "Targeting XIAP Via Degradation of MDM-2 By MX69 in Aggressive Lymphomas". Blood 132, Supplement 1 (29 de novembro de 2018): 5379. http://dx.doi.org/10.1182/blood-2018-99-118480.
Texto completo da fonteToubai, Tomomi, Corinne Rossi, Katherine Oravecz-Wilson, Cynthia Zajac, Hideaki Fujiwawa, Stuart Brabbs, Julia Wu, Yaping Sun, John M. Magenau e Pavan R. Reddy. "IAPs Protect Host Target Tissues from Graft-Versus-Host Disease (GVHD)". Blood 128, n.º 22 (2 de dezembro de 2016): 810. http://dx.doi.org/10.1182/blood.v128.22.810.810.
Texto completo da fonteRYAN, Ciara A., Henning R. STENNICKE, Victor E. NAVA, Jennifer B. BURCH, J. Marie HARDWICK e Guy S. SALVESEN. "Inhibitor specificity of recombinant and endogenous caspase-9". Biochemical Journal 366, n.º 2 (1 de setembro de 2002): 595–601. http://dx.doi.org/10.1042/bj20020863.
Texto completo da fonteAkbar, Rozmeen, Mati Ur Rehman, Asra Khan, Numair Belgaumi, Iman M. Farooqui, Aafia S. Arain, Azhar Hussain Rajabali e Kulsoom Ghias. "Abstract 2549: Targeting PI3Kinase AKT pathway and anti-apoptotic protein XIAP in chemotherapy-resistant colorectal cancer cells". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 2549. http://dx.doi.org/10.1158/1538-7445.am2023-2549.
Texto completo da fonteKater, Arnon P., Roman Rieger, Kate Welsh, Adel Nefzi, Richard Houghten, John C. Reed, Clemencia Pinilla e Thomas J. Kipps. "Inhibition of XIAP Enhances Specific Cytotoxic T Lymphocyte (CTL) Killing and CD20-Directed Antibody-Dependent Cellular Cytotoxicity of Chronic Lymphocytic Leukemia B Cells." Blood 104, n.º 11 (16 de novembro de 2004): 3475. http://dx.doi.org/10.1182/blood.v104.11.3475.3475.
Texto completo da fonteCho, Seung-Ju, Young-Jong Kim, Young-Joon Surh, B. Moon Kim e Seung-Ki Lee. "Ibulocydine Is a Novel Prodrug Cdk Inhibitor That Effectively Induces Apoptosis in Hepatocellular Carcinoma Cells". Journal of Biological Chemistry 286, n.º 22 (8 de abril de 2011): 19662–71. http://dx.doi.org/10.1074/jbc.m110.209551.
Texto completo da fonteEyrisch, Susanne, Jose L. Medina-Franco e Volkhard Helms. "Transient pockets on XIAP-BIR2: toward the characterization of putative binding sites of small-molecule XIAP inhibitors". Journal of Molecular Modeling 18, n.º 5 (30 de agosto de 2011): 2031–42. http://dx.doi.org/10.1007/s00894-011-1217-y.
Texto completo da fonteVan Themsche, Céline, Isabelle Mathieu, Sophie Parent e Eric Asselin. "Transforming Growth Factor-β3 Increases the Invasiveness of Endometrial Carcinoma Cells through Phosphatidylinositol 3-Kinase-dependent Up-regulation of X-linked Inhibitor of Apoptosis and Protein Kinase C-dependent Induction of Matrix Metalloproteinase-9". Journal of Biological Chemistry 282, n.º 7 (6 de dezembro de 2006): 4794–802. http://dx.doi.org/10.1074/jbc.m608497200.
Texto completo da fonteGu, Juan J., Samuel J. Thompson, Cory Mavis, Matthew J. Barth, Pallawi Torka e Francisco J. Hernandez-Ilizaliturri. "Targeting MDM2 and XIAP By Idasanutlin in Diffuse Large B-Cell Lymphoma". Blood 134, Supplement_1 (13 de novembro de 2019): 5301. http://dx.doi.org/10.1182/blood-2019-129009.
Texto completo da fonteHuerta-Yepez, Sara, Mario Vega, Dorina Gui, Jonathan Said e Benjamin Bonavida. "Analysis of YY1 and XIAP Expression, Proteins That Regulate Resistance, in AIDS-NHL Tissue Arrays." Blood 106, n.º 11 (16 de novembro de 2005): 1933. http://dx.doi.org/10.1182/blood.v106.11.1933.1933.
Texto completo da fonteKawakami, Atsushi, Tomoki Nakashima, Hideaki Sakai, Satoshi Urayama, Satoshi Yamasaki, Ayumi Hida, Masahiko Tsuboi et al. "Inhibition of Caspase Cascade by HTLV-I Tax Through Induction of NF-κB Nuclear Translocation". Blood 94, n.º 11 (1 de dezembro de 1999): 3847–54. http://dx.doi.org/10.1182/blood.v94.11.3847.
Texto completo da fonteKawakami, Atsushi, Tomoki Nakashima, Hideaki Sakai, Satoshi Urayama, Satoshi Yamasaki, Ayumi Hida, Masahiko Tsuboi et al. "Inhibition of Caspase Cascade by HTLV-I Tax Through Induction of NF-κB Nuclear Translocation". Blood 94, n.º 11 (1 de dezembro de 1999): 3847–54. http://dx.doi.org/10.1182/blood.v94.11.3847.423a24_3847_3854.
Texto completo da fonteKitada, Shinichi, Juan M. Zapata, Michael Andreeff e John C. Reed. "Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia". Blood 96, n.º 2 (15 de julho de 2000): 393–97. http://dx.doi.org/10.1182/blood.v96.2.393.
Texto completo da fonteKitada, Shinichi, Juan M. Zapata, Michael Andreeff e John C. Reed. "Protein kinase inhibitors flavopiridol and 7-hydroxy-staurosporine down-regulate antiapoptosis proteins in B-cell chronic lymphocytic leukemia". Blood 96, n.º 2 (15 de julho de 2000): 393–97. http://dx.doi.org/10.1182/blood.v96.2.393.014k47_393_397.
Texto completo da fonteTodorovic, Lidija, Gorana Stamenkovic, Biljana Vucetic-Tadic, Kazuo Umezawa, Ana Bozovic, Shunichi Yamashita e Boban Stanojevic. "Synergistic effect of 17-allylamino-17-demethoxygeldanamycin with dehydroxymethylepoxyquinomicin on the human anaplastic thyroid carcinoma cell line KTC2". Archives of Biological Sciences, n.º 00 (2020): 55. http://dx.doi.org/10.2298/abs201010055t.
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