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Bramstedt, Katrina A. "Increasing Donation Opportunities for Vascularized Composite Allografts". Progress in Transplantation 26, n.º 4 (20 de agosto de 2016): 372–77. http://dx.doi.org/10.1177/1526924816664080.
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There are 40 vascularized composite allotransplant programs across 5 continents served by 31 organ procurement organizations (or equivalent). The organizations’ websites inform about organ and tissue donation. This research explored worldwide educational efforts on vascularized composite allograft (VCAG) donation via their corporate websites as well as options within donor registries and donor card systems to indicate a VCAG donation preference. Of these, 13 (41.9%) of 31 had VCAG content and 7 (22.6%) of 31 offered a mechanism for individuals to voice a preference about VCAG donation through an opt in donor registry or card or an opt out registry. In North America, the only donor registration/card system that facilitated VCAG donation is in Mexico. The resistance to consent for VACG donation is likely due to poor public education and the personal nature of face, hand, uterus, and penile allografts. Efforts to reduce this resistance can begin with the assistance of website content, registries, and donor cards.
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Hoyle, Victoria, Madison T. Flasco, Jiyeong Choi, Elizabeth J. Cieniewicz, Heather McLane, Keith Perry, Gerald Dangl et al. "Transmission of Grapevine Red Blotch Virus by Spissistilus festinus [Say, 1830] (Hemiptera: Membracidae) between Free-Living Vines and Vitis vinifera ‘Cabernet Franc’". Viruses 14, n.º 6 (26 de maio de 2022): 1156. http://dx.doi.org/10.3390/v14061156.
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Grapevine red blotch disease emerged within the past decade, disrupting North American vine stock production and vineyard profitability. Our understanding of how grapevine red blotch virus (GRBV), the causal agent of the disease, interacts with its Vitis hosts and insect vector, Spissistilus festinus, is limited. Here, we studied the capabilities of S. festinus to transmit GRBV from and to free-living vines, identified as first-generation hybrids of V. californica and V. vinifera ‘Sauvignon blanc’ (Vcal hybrids), and to and from V. vinifera ‘Cabernet franc’ (Vvin Cf) vines. The transmission rate of GRBV was high from infected Vcal hybrid vines to healthy Vcal hybrid vines (77%, 10 of 13) and from infected Vvin Cf vines to healthy Vcal hybrid vines (100%, 3 of 3). In contrast, the transmission rate of GRBV was low from infected Vcal hybrid vines to healthy Vvin Cf vines (15%, 2 of 13), and from infected Vvin Cf vines to healthy Vvin Cf vines (19%, 5 of 27). No association was found between transmission rates and GRBV titer in donor vines used in transmission assays, but the virus titer was higher in the recipient leaves of Vcal hybrid vines compared with recipient leaves of Vvin Cf vines. The transmission of GRBV from infected Vcal hybrid vines was also determined to be trans-stadial. Altogether, our findings revealed that free-living vines can be a source for the GRBV inoculum that is transmissible by S. festinus to other free-living vines and a wine grape cultivar, illustrating the interconnected roles of the two virus hosts in riparian areas and commercial vineyards, respectively, for virus spread. These new insights into red blotch disease epidemiology will inform the implementation of disease management strategies.
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Blake, Damian, e David Gallagher. "Examining the Development of the Victorian Certificate of Applied Learning and Its Implications for Schools and Teacher Education in Australia". Journal of Applied Learning in Higher Education 01 (2009): 49–71. http://dx.doi.org/10.57186/jalhe_2009_v1a3p49-71.
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The Victorian Certificate of Applied Learning (VCAL) is a very successful senior secondary school qualification introduced in the Australian state of Victoria in 2002. Applied learning in the VCAL engages senior students in a combination of work-based learning, service-learning, and project-based learning and aims to provide them with the skills, knowledge, and attitudes to make informed choices regarding pathways to work and further education. The program has enjoyed rapid growth and its system-wide adoption by Victorian secondary schools, Technical and Further Education (TAFE) institutions, Registered Training Organizations (RTOs), and Adult and Community Education (ACE) providers has broadened significantly the range of senior schooling pathway options for young people. This paper will examine reasons for developing an applied learning senior secondary certificate and its rapid growth in Victoria since 2002. The authors draw on a number of case studies to profile the unique nature of applied learning in the VCAL, including its dimensions of service learning, work-based learning, and project-based learning. These case studies are also used to discuss a number of implications that have emerged from the use of applied learning in the VCAL, including approaches to teaching and assessment that will support applied learning and the development of new partnerships between VCAL providers and community partners. Finally, the paper considers significant implications the VCAL has created for teacher education in Victoria by discussing the new Graduate Diploma of Education (Applied Learning) developed by Deakin University.
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Georgiou, Gerasimos Odysseas, Francesco Tarallo, Enrico Marchetti e Sergio Bizzarro. "Overview of the Effect of Different Regenerative Materials in Class II Furcation Defects in Periodontal Patients". Materials 15, n.º 9 (28 de abril de 2022): 3194. http://dx.doi.org/10.3390/ma15093194.
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The aim of this review was to give an overview of the outcomes of the use of different regenerative materials to treat molars with class II furcation defects in patients with periodontitis in comparison with open flap debridement (OFD). A search of five databases (PubMed-Medline, Embase, Cochrane, Scopus and Web of Science) was conducted up to and including January 2022. According to the PICOS guidelines, only randomized control trials (S) considering periodontal patients with at least one molar with a class II furcation involvement (P) treated with regenerative materials (I) in comparison to OFD as control treatment (C) and a minimum follow-up period of 6 months were included. Vertical clinical attachment level (VCAL) was considered as the primary outcome (O), while horizontal clinical attachment level (HCAL), horizontal probing depth (HPD) and vertical probing depth (VPD) were considered as secondary outcomes. The search through the databases initially identified 1315 articles. Only 25 of them met the eligibility criteria and were included. The studies were grouped in four macro-categories according to the material used: absorbable and non-absorbable membranes, blood derivatives and a combination of different materials. The greater part of the included studies reported a statistically significant difference in using regenerative materials when compared to OFD. The blood derivatives groups reported a range of mean changes in VCAL of 0.86–4.6 mm, absorbable membrane groups reported −0.6–3.75 mm, non-absorbable membranes groups reported −2.47–4.1 mm, multiple materials groups reported −1.5–4.87 mm and enamel matrix derivatives reported a mean change in VCAL of 1.45 mm. OFD showed a range of mean VCAL changes of −1.86–2.81 mm. Although no statistical analysis was performed, the use of regenerative materials may be considered moderately beneficial in the treatment of molars with grade II furcation involvement. However, the substantial heterogeneity in the protocols’ design does not allow us to draw definitive conclusions. In addition, low levels of evidence for morbidity and patient-centered outcomes were reported.
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Hirsz, Marta, e Krystyna Nagrodzka-Godycka. "Verification of selected calculation methods regarding shear strength in beams without web reinforcement". MATEC Web of Conferences 219 (2018): 03015. http://dx.doi.org/10.1051/matecconf/201821903015.
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The purpose of the article was to compare selected calculation methods regarding shear strength in reinforced concrete beams without web reinforcement. Several calculation methods were tested. This included codes: PN-EN 1992-1-1:2008, ACI 318-14 and fib Model Code for Concrete Structures 2010. The analysis also consists of authorial methods published in technical literature. Calculations of shear strengths were made based on experimental works found in literature. The shear strength ratios Vtest/Vcalc were chosen to be the yardstick of comparison, where Vtest is the experimental shear strength and Vcalc is the calculated shear strength. A wide range of variables including shear span/depth ratio, compressive strength of concrete, longitudinal steel percentage helped to verify the applicability of calculation methods. Although most of authorial techniques proved to be unstable, they succeeded to show that codes’ formulas for shear strength may still be improved. The presented article is a part of Authors’ long term research in the matter and a new chapter of their study now concerning beams without web reinforcement.
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Bailey, Rowena, Greg Williams, Irem Sahin e Marcelle Cacciattolo. "The VCAL Experience: Unpacking Innovative Teaching and Learning Strategies". International Journal of Interdisciplinary Social Sciences: Annual Review 2, n.º 2 (2007): 207–16. http://dx.doi.org/10.18848/1833-1882/cgp/v02i02/52255.
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Tarallo, Francesco, Leonardo Mancini, Luciano Pitzurra, Sergio Bizzarro, Michele Tepedino e Enrico Marchetti. "Use of Platelet-Rich Fibrin in the Treatment of Grade 2 Furcation Defects: Systematic Review and Meta-Analysis". Journal of Clinical Medicine 9, n.º 7 (3 de julho de 2020): 2104. http://dx.doi.org/10.3390/jcm9072104.
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In periodontitis patients, furcation defects are crucial sites to regenerate due to their complex anatomy. Various modern surgical techniques and use of biomaterials have been suggested in the literature. Among all, platelet-rich fibrin (PRF) has potential in tissue regeneration thanks to its role in the release of growth factors. Therefore, the purpose of this study was to evaluate the beneficial effect of the addition of PRF to open flap debridement (OFD) or as an adjuvant to other biomaterials such as bone grafts in the treatment of grade 2 mandibular furcation defects. Systematic research was carried out on the databases Medline, Scopus, Embase, and Cochrane Library and registered on PROSPERO (CRD42020167662). According to the PICO guidelines by Cochrane, randomized trials and prospective non-randomized trials were evaluated, with a minimum follow-up period of 6 months. The inclusion criteria were the absence of systemic diseases, non-smoking patients, and a population aged from 18 to 65 years. Vertical pocket probing depth (PPD), vertical clinical attachment level (VCAL), and gingival recession (REC) were the primary outcomes. Vertical furcation depth (VFD), and the percentage of bone defect fill (%v-BDF) were considered as secondary outcomes. A meta-analysis of the primary and secondary outcomes was performed. Publication bias was assessed through a funnel plot. Eighty-four articles were initially extracted. Eight randomized clinical trials were analyzed according to the exclusion and inclusion criteria. The Quality assessment instrument (QAI) revealed four articles at low risk of bias, one at moderate, and three at high risk of bias. The metanalysis showed significant data regarding PPD, VCAL, VFD and %v-BDF in the comparison between PRF + OFD vs. OFD alone. The adjunct of PRF to a bone graft showed a significant difference for VCAL and a not statistically significant result for the other involved parameters. In conclusion, the adjunctive use of PRF to OFD seems to enhance the periodontal regeneration in the treatment of grade 2 furcation defects. The combination of PRF and bone graft did not show better clinical results, except for VCAL, although the amount of literature with low risk of bias is scarce. Further well-designed studies to evaluate the combination of these two materials are therefore needed.
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Ganim, Zoe, e Erica Frydenberg. "Attitudes to School, Coping,Wellbeing and Stress: An Examination of VCAL Students". Australian Educational and Developmental Psychologist 23, n.º 1 (2006): 7–26. http://dx.doi.org/10.1017/s0816512200028844.
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AbstractOne hundred and fifty-seven students (aged 15 to 19 years) enrolled in the Victorian Certificate of Applied Learning (VCAL) program completed the Adolescent Coping Scale (ACS), and measures of school-related stress, attitudes to school and wellbeing. In general, VCAL students reported a positive attitude to school, high levels of wellbeing, low levels of school-related stress, and used a wide range of coping strategies. Gender differences and attitudinal differences were found in relation to coping strategies used, wellbeing, and stress. Discriminant analysis indicated that for females, low levels of school-related stress and frequent use of the ‘work hard’coping strategy significantly predicted a positive attitude to school, while for males high levels of wellbeing, and the frequent use of ‘work hard’, ‘focus on the positive’, and minimal use of ‘tension reduction’ predicted positive attitudes to school. The findings are discussed in light of current research and recommendations for interventions are proposed.
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Sun, Haoyue, Zhicheng Yu e Bining Zhang. "Research on short-term power load forecasting based on VMD and GRU". PLOS ONE 19, n.º 7 (11 de julho de 2024): e0306566. http://dx.doi.org/10.1371/journal.pone.0306566.
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The traditional method for power load forecasting is susceptible to various factors, including holidays, seasonal variations, weather conditions, and more. These factors make it challenging to ensure the accuracy of forecasting results. Additionally, there is a limitation in extracting meaningful physical signs from power data, which ultimately reduces prediction accuracy. This paper aims to address these issues by introducing a novel approach called VCAG (Variable Mode Decomposition—Convolutional Neural Network—Attention Mechanism—Gated Recurrent Unit) for combined power load forecasting. In this approach, we integrate Variable Mode Decomposition (VMD) with Convolutional Neural Network (CNN). VMD is employed to decompose power load data, extracting valuable time-frequency features from each component. These features then serve as input for the CNN. Subsequently, an attention mechanism is applied to give importance to specific features generated by the CNN, enhancing the weight of crucial information. Finally, the weighted features are fed into a Gated Recurrent Unit (GRU) network for time series modeling, ultimately yielding accurate load forecasting results.To validate the effectiveness of our proposed model, we conducted experiments using two publicly available datasets. The results of these experiments demonstrate that our VCAG method achieves high accuracy and stability in power load forecasting, effectively overcoming the limitations associated with traditional forecasting techniques. As a result, this approach holds significant promise for broad applications in the field of power load forecasting.
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Jahanshahi, M., J. Rowe, T. Saleem, R. G. Brown, P. Limousin-Dowsey, J. C. Rothwell, D. G. T. Thomas e N. P. Quinn. "Striatal Contribution to Cognition: Working Memory and Executive Function in Parkinson's Disease before and after Unilateral Posteroventral Pallidotomy". Journal of Cognitive Neuroscience 14, n.º 2 (1 de fevereiro de 2002): 298–310. http://dx.doi.org/10.1162/089892902317236911.
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The basal ganglia are intimately connected to the frontal cortex via five fronto-striatal circuits. While the role of the frontal cortex in cognition has been extensively studied, the contribution of the basal ganglia to cognition has remained less clear. In Parkinson's disease, posteroventral pallidotomy (PVP) involves surgical lesioning of the internal section of the globus pallidus (GPi, the final output pathway from the basal ganglia) to relieve the motor symptoms of the disorder. PVP in Parkinson's disease provides a unique opportunity to investigate the impact of disruption of striatal outflow to the frontal cortex on cognition. We assessed executive function and working memory after withdrawal of medication in 13 patients with Parkinson's disease before and 3 months after unilateral PVP compared to 12 age-and IQ-matched normals assessed twice with an interval of 3 months. The tests used were: Wisconsin Card Sorting (WCST), Self-Ordered Random Number Sequences, Missing Digit Test, Paced Visual Serial Addition Test (PVSAT), and Visual Conditional Associative Learning Test (VCALT). After PVP, the patients performed significantly better on the Self-Ordered Random Number Sequences and the WCST, an improvement that was also observed in the normals across the two assessment and is therefore likely to reflect practice effects. Relative to the normals, the patients showed significant differential change following PVP on the Missing Digit Test and PVSAT, on which they performed worse after compared to before surgery, while the controls performed better on the second assessment. For the patients, performance on the VCALT also indicated deterioration after PVP, but the changes approached significance. The side of PVP had no effect on the results. The pattern of change observed 3 months after PVP was maintained at 15-month follow-up. The results suggest that striatal outflow to the frontal cortex may be essential for those aspects of executive function that showed deterioration after PVP. &
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Siddiqui, Zeba Rahman, Rajesh Jhingran, Vivek Kumar Bains, Ruchi Srivastava, Rohit Madan e Iram Rizvi. "Comparative evaluation of platelet-rich fibrin versus beta-tri-calcium phosphate in the treatment of Grade II mandibular furcation defects using cone-beam computed tomography". European Journal of Dentistry 10, n.º 04 (outubro de 2016): 496–506. http://dx.doi.org/10.4103/1305-7456.195160.
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ABSTRACT Objective: The objective of the study was to evaluate clinically and radiographically the efficacy of platelet-rich fibrin (PRF) versus β-tri-calcium phosphate (β-TCP) in the treatment of Grade II mandibular furcation defects. Materials and Methods: Forty-five Grade II furcation defect in mandibular molars which were assigned to open flap debridement (OFD) with PRF Group I (n = 15), to OFD with β-TCP Group II (n = 15), and to OFD alone Group III (n = 15) were analyzed for clinical parameters (probing pocket depth [PPD], vertical clinical attachment level [VCAL], horizontal clinical attachment level [HCAL], gingival recession, relative vertical height of furcation [r-VHF], and relative horizontal depth of furcation [r-HDF]) and radiographical parameters (horizontal depth of furcation [H-DOF], vertical height of furcation [V-HOF]) using cone-beam computed tomography (CBCT) at 6 months interval. Results: For clinical parameters, reduction in PPD and gain in VCAL and HCAL were higher in Group II as compared to Group I. Change in r-VHF and r-HDF was greater in Group II as compared to Group I. Mean percentage clinical vertical defect fill was higher in Group II as compared to Group I (58.52% ± 11.68% vs. 53.24% ± 13.22%, respectively). On CBCT, mean change at 6 months for all parameters showed nonsignificant difference between the two experimental groups. Mean change in V-HOF was higher in Group I as compared to Group II, but mean change in H-DOF and furcation width was more in Group II as compared to Group I. Conclusion: For both experimental and control groups, there was statistically significant improvement at 6 months follow-up from baseline values.
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Islam, Shakira S., e Kochi Ismail. "Mixed alkali effect in sodium thiosulfate pentahydrate melt". Canadian Journal of Chemistry 66, n.º 2 (1 de fevereiro de 1988): 242–45. http://dx.doi.org/10.1139/v88-040.
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Density and electrical conductance measurements of 0.35[XNaNO3 + (1 − X)KNO3] + 0.65Na2S2O3•5H2O melt were made as functions of temperature and X. Molar volume, V, is found to be additive. The percent deviation of Vext (extrapolated V of the pure solute from the plot of V vs. total added alkali ion fraction) from Vcal (calculated V of the pure solute from its high temperature density data) increases monotonically as the amount of NaNO3 in the hydrate melt increases, thereby manifesting a "structure-forming" tendency of NaNO3. The non-Arrhenius temperature dependence of molar conductance, Λ is analyzed in terms of the Vogel–Tammann–Fulcher (VTF) equation. Mixed alkali effect (MAE) has been observed on Λ and T0 (ideal glass transition temperature). A competitive polarization model has been used to explain the MAE on Λ.
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Broadbent, Robyn, e Theo Papadopoulos. "What alternative? A snapshot of VCAL as an alternative to senior secondary education in the western region of Melbourne". Research in Post-Compulsory Education 18, n.º 3 (setembro de 2013): 209–20. http://dx.doi.org/10.1080/13596748.2013.819255.
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Gaber, Dalia Shawky, Nevine Hassan Kheir El Din, Hamdy Ahmed Nassar, Mostafa Saad El-Din Ashmawy e Ola Mohamed Ezzatt. "Clinical and Biochemical Assessment of Lycopene Gel Combined With Nanohydroxyapatite Graft in Treatment of Grade II Furcation Defects: A Randomized Controlled Clinical Study". Perio J 5, n.º 1 (31 de dezembro de 2021): 28–37. http://dx.doi.org/10.26810/perioj.2021.a4.
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Background: This study aimed to evaluate the effects of lycopene gel, as a natural antioxidant, mixed with a nanohydroxyapatite graft (NHG) covered by an occlusive resorbable collagen membrane (CM) in the surgical treatment of grade II furcation defects and on the gingival crevicular fluid (GCF) levels of 8-hydroxydeoxyguanosine (8-OHdG), as a marker of oxidative injury. Methods: In this randomized controlled clinical study a total of 24 patients with grade II furcation defects were randomly assigned into three equal groups. Furcation defects in group I were managed with lycopene gel mixed with NHG and CM, group II with NHG and CM, and group III with open flap debridement only. Site-specific changes in clinical parameters including probing depth (PD), vertical clinical attachment level (VCAL), horizontal clinical attachment level (HCAL), radiographic maximum vertical depth (MAX V), and maximum horizontal depth (MAX H) were measured at baseline and six months postoperatively. Gingival crevicular fluid levels of 8-OHdG were analyzed using enzyme-linked immunosorbent assay (ELISA) at baseline, one week, and three months. Results: Surgical management of grade II furcation defects resulted in a significant reduction in PD and 8-OHdG levels and a gain in CAL, MAX V, and MAX H in all groups. The differences between lycopene treated sites compared to NHG and CM alone were not significant at six months but demonstrated significantly superior clinical parameters compared to open flap debridement alone. Conclusion: Lycopene does not confer a benefit when combined with NHG in the surgical treatment of grade II furcation defects.
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Bowden, Mark P., Subhash Abhayawansa e John Bahtsevanoglou. "Overconfidence of vocational education students when entering higher education". Education + Training 57, n.º 4 (11 de maio de 2015): 429–47. http://dx.doi.org/10.1108/et-02-2014-0012.
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Purpose – There is evidence that students who attend Technical and Further Education (TAFE) prior to entering higher education underperform in their first year of study. The purpose of this paper is to examine the role of self-efficacy in understanding the performance of students who completed TAFE in the previous year in a first year subject of microeconomics in a dual sector university in Melbourne, Australia. Design/methodology/approach – The study utilises data collected by surveys of 151 students. Findings – A student’s self-efficacy is positively associated with their marks in a first year subject of microeconomics. However, the relationship between final marks and self-efficacy is negative for those students who attended TAFE in the previous year suggesting that they suffer from the problem of overconfidence. When holding self-efficacy constant, using econometric techniques, TAFE attendance is found to be positively related to final marks. Research limitations/implications – The findings are exploratory (based on a small sample) and lead to a need to conduct cross institutional studies. Practical implications – The research points to the need for early interventions so that TAFE students perform well in their first year of higher education. It also points to potential issues in the development of Victorian Certificate of Applied Learning (VCAL) programs. Originality/value – To the best of the authors’ knowledge, this is the first paper to examine the inter-related impact of attendance at TAFE in the previous year and self-efficacy on the subsequent academic performance of TAFE students.
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Mata-González, Ricardo, Benjamín Figueroa-Sandoval, Fernando Clemente e Mario Manzano. "VEGETATION CHANGES AFTER LIVESTOCK GRAZING EXCLUSION AND SHRUB CONTROL IN THE SOUTHERN CHIHUAHUAN DESERT". Western North American Naturalist 67, n.º 1 (janeiro de 2007): 63–70. http://dx.doi.org/10.3398/1527-0904(2007)67[63:vcalge]2.0.co;2.
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Panda, Sourav, Lorena Karanxha, Funda Goker, Anurag Satpathy, Silvio Taschieri, Luca Francetti, Abhaya Chandra Das, Manoj Kumar, Sital Panda e Massimo Del Fabbro. "Autologous Platelet Concentrates in Treatment of Furcation Defects—A Systematic Review and Meta-Analysis". International Journal of Molecular Sciences 20, n.º 6 (17 de março de 2019): 1347. http://dx.doi.org/10.3390/ijms20061347.
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Background: The aim of this review was to evaluate the adjunctive effect of autologous platelet concentrates (APCs) for the treatment of furcation defects, in terms of scientific quality of the clinical trials and regeneration parameters assessment. Methods: A systematic search was carried out in the electronic databases MEDLINE, SCOPUS, CENTRAL (Cochrane Central Register of Controlled Trials), and EMBASE, together with hand searching of relevant journals. Two independent reviewers screened the articles yielded in the initial search and retrieved the full-text version of potentially eligible studies. Relevant data and outcomes were extracted from the included studies. Risk of bias assessment was also carried out. The outcome variables, relative to baseline and post-operative defect characteristics (probing pocket depth (PPD), horizontal and vertical clinical attachment loss (HCAL, VCAL), horizontal and vertical furcation depth (HFD, VFD) were considered for meta-analysis. Results: Ten randomized trials were included in this review. Only one study was judged at high risk of bias, while seven had a low risk, testifying to the good level of the evidence of this review. The meta-analysis showed a favorable effect regarding all outcome variables, for APCs used in adjunct to open flap debridement (p < 0.001). Regarding APCs in adjunct to bone grafting, a significant advantage was found only for HCAL (p < 0.001, mean difference 0.74, 95% CI 0.54, 0.94). The sub-group analysis showed that both platelet-rich fibrin and platelet-rich plasma in adjunct with open flap debridement, yielded significantly favorable results. No meta-analysis was performed for APCs in combination with guided tissue regeneration (GTR) as only one study was found. Conclusion: For the treatment of furcation defects APCs may be beneficial as an adjunct to open flap debridement alone and bone grafting, while limited evidence of an effect of APCs when used in combination with GTR was found.
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Agarwal, Ashish, R. G. Shiva Manjunath, Priyamwada Sethi e G. Shiva Shankar. "Platelet-rich fibrin in combination with decalcified freeze-dried bone allograft for the management of mandibular degree II furcation defect: A randomised controlled clinical trial". Singapore Dental Journal 39, n.º 01 (dezembro de 2019): 33–40. http://dx.doi.org/10.1142/s2214607519500032.
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Background: Treatment of furcation involvement of molars with periodontal disease remains challenging and unpredictable. Platelet-rich fibrin (PRF) has received the attention of researchers due to its pleiotropic properties essential for periodontal wound healing. The osteoinductive property of demineralized freeze-dried bone allograft (DFDBA) has been successfully used in periodontal regeneration. Aim: The present study aimed to explore the effectiveness of PRF alone and with DFDBA in the treatment of mandibular degree II furcation defects in subjects with chronic periodontitis. Material and Methods: Patients treated were from the Department of Periodontology and Implantology, Institute of Dental Sciences, Bareilly. A total of 60 mandibular molars were treated with either open flap debridement (OFD) alone, [Formula: see text] combination or [Formula: see text] combination. The soft and hard tissue parameters such as vertical probing depth (VPD), vertical clinical attachment level (VCAL), gingival marginal level (GML), horizontal probing depth (HPD), vertical bone fill (VBF), horizontal bone fill (HBF) and furcation width (FW) were determined at baseline and 9 months postoperatively. A paired [Formula: see text]-test was conducted to assess the statistical significance between time period within each group for clinical and radiographic parameters. ANOVA and post-hoc Tukey’s tests were also conducted for intergroup comparison of soft and hard tissue parameters. Statistical significance was set at [Formula: see text]. Results and Discussion: After 9 months, all treatment groups showed significant ([Formula: see text]) improvement in soft and hard tissue parameters, except GML in all the three groups and HBF and FW in the OFD group as compared to baseline. The mean VBF change was highest in the [Formula: see text] group ([Formula: see text]) mm, followed by that in the [Formula: see text] and OFD groups ([Formula: see text] and [Formula: see text][Formula: see text]mm, respectively). Conclusions: It was shown that both [Formula: see text] and [Formula: see text] combinations were significantly advantageous for the management of mandibular degree II furcation defects. However, the [Formula: see text] combination has significantly greater benefits than [Formula: see text] combination in terms of VBF.
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Merhaut, Donald J., Lea Corkidi, Maren Mochizuki, Toan Khuong, Julie Newman, Ben Faber, Oleg Daugovish e Sonya Webb. "Implementation of Best Management Practices to Reduce Agricultural Total Maximum Daily Loads in the Calleguas Creek and Santa Clara River Watersheds: A Case Study of Water Contaminant Mitigation in California". HortScience 48, n.º 9 (setembro de 2013): 1109–12. http://dx.doi.org/10.21273/hortsci.48.9.1109.
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Agriculture is a major industry in California, with cool-season crops grown along the state’s coasts, warm-season crops grown in the hot deserts, and many temperate crops grown in the state’s valleys. In coastal communities such as Ventura County, the Calleguas Creek and the Santa Clara River watersheds have 50,000 and 60,000 irrigated acres of farm crops, respectively. These watersheds are considered impaired by nutrients, salts, pesticides, and other agricultural contaminants. Mitigation of chemical and sediment runoff through grower-implemented best management practices (BMPs) is therefore one of the highest priorities in the Los Angeles Regional Water Quality Control Board Basin Plan. A 3-year project was designed to assist Ventura County growers in meeting regional water quality objectives. The University of California Cooperative Extension Ventura County and the University of California, Riverside, collaborated with the Ventura County Resource Conservation District and the Ventura County Agricultural Irrigated Lands Group (VCAILG) to address three project goals: increase grower and landowner understanding of local agricultural water quality issues; identify gaps or deficiencies in current management practices in agricultural operations; and reduce the contribution of nutrients, pesticides, and other pollutants to impaired water bodies. To achieve these goals, 469 surveys of agricultural water quality management practices were collected to assess the extent of current adoption of BMPs. Over 160 growers who farm more than 14,000 acres that drain into Calleguas Creek and 7,000 acres that drain into the Santa Clara River watersheds were assisted. Using the survey, growers developed site-specific farm water quality plans and received on-farm recommendations for BMPs. Additionally, 12 water quality educational programs, “including demonstrations of successful BMPs,” were developed and more than 2500 copies of educational materials published by the University of California, the Resource Conservation District, and the Natural Resources Conservation Service of the U.S. Department of Agriculture were distributed at on-farm visits, workshops, and other grower events. The project resulted in improved understanding, by growers and landowners, of water quality issues and significantly increased the implementation of appropriate on-farm BMPs to protect water quality. Nearly 100 new BMPs primarily aimed at managing erosion, sediment movement, and irrigation runoff were identified and documented through annual reassessments for more than 8000 acres draining into Calleguas Creek. A total of 518 people attended the educational programs, and over 90% of participants who completed evaluations rated the programs highly. In the final year of the project, 75% of attendees indicated they plan to implement new BMPs within the next 5 years, especially in the areas of irrigation, erosion, and pest management.
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Chow, Emma, e Pol Dominic Miles-McCann. "Investigating What Victorian Certificate of Applied Learning Students Seek in a Counselling Service". Psychotherapy and Counselling Journal of Australia 7, n.º 1 (1 de setembro de 2019). http://dx.doi.org/10.59158/001c.71116.
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Adolescents enrolled in community Victorian Certificate of Applied Learning (VCAL) programs frequently experience a wide range of serious life issues that can disrupt their educational experience, and these students may benefit from the application of counselling. The current study examines how organisations providing the VCAL can implement effective counselling services that will be utilised by students. At present, no existing studies examine what factors would encourage VCAL students to utilise a mental health service provided by their educational program. Data was collected through a web-based qualitative survey. Thematic analysis was applied to the survey responses, and the themes that emerged included interpersonal stress, desire for mutual respect in counselling, and that youth prefer to be autonomous. Participants expressed wanting counselling services which are accessible, flexible, support their own problem solving, and encourage a warm, respectful therapeutic relationship.
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Muraru, Denisa, Marco Previtero, Roberto C. Ochoa-Jimenez, Andrada C. Guta, Stefano Figliozzi, Dario Gregori, Daniele Bottigliengo, Gianfranco Parati e Luigi P. Badano. "Prognostic validation of partition values for quantitative parameters to grade functional tricuspid regurgitation severity by conventional echocardiography". European Heart Journal - Cardiovascular Imaging, 28 de novembro de 2020. http://dx.doi.org/10.1093/ehjci/jeaa282.
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Abstract Aims Quantitative echocardiography parameters are seldom used to grade tricuspid regurgitation (TR) severity due to relative paucity of validation studies and lack of prognostic data. To assess the relationship between TR severity and the composite endpoint of death and hospitalization for congestive heart failure (CHF); and to identify the threshold values of vena contracta width (VCavg), effective regurgitant orifice area (EROA), regurgitant volume (RegVol), and regurgitant fraction (RegFr) to define low, intermediate, and high-risk TR based on patients’ outcome data. Methods and results A cohort of 296 patients with at least mild TR underwent 2D, 3D, and Doppler echocardiography. We built statistical models (adjusted for age, NYHA class, left ventricular ejection fraction, and pulmonary artery systolic pressure) for VCavg, EROA, RegVol, and RegFr to study their relationships with the hazard of outcome. The tertiles of the derived hazard values defined the threshold values of the quantitative parameters for TR severity grading. During 47-month follow-up, 32 deaths and 72 CHF occurred. Event-free rate was 14%, 48%, and 93% in patients with severe, moderate, and mild TR, respectively. Severe TR was graded as VCavg > 6 mm, EROA > 0.30 cm2, RegVol > 30 mL, and RegF > 45%. Conclusion This outcome study demonstrates the prognostic value of quantitative parameters of TR severity and provides prognostically meaningful threshold values to grade TR severity in low, intermediate, and high risk.
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Previtero, M., A. C. Guta, R. C. Ochoa-Jimenez, S. Figliozzi, C. Palermo, A. Baritussio, A. Cecchetto et al. "38 Prognostic validation of partition values obtained with conventional two-dimensional and doppler echocardiography to grade tricuspid regurgitation severity". European Heart Journal - Cardiovascular Imaging 21, Supplement_1 (1 de janeiro de 2020). http://dx.doi.org/10.1093/ehjci/jez319.
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Abstract Background Morbidity and mortality associated with severe tricuspid regurgitation (TR) have prompted interest in new corrective transcatheter procedures. However, to properly select patients for interventional procedures, and to assess their effectiveness, a reliable and reproducible grading system of TR severity is mandatory. However, the cut-off values used by current guidelines to differentiate among mild, moderate and severe TR lack clinical validation. Purpose We aimed to obtain the threshold values of the currently recommended quantitative echocardiographic parameters used to grade TR severity using pts’ outcome as a reference. Methods 296 pts, with at least mild TR and complete 2D, 3D and Doppler echocardiographic study, were enrolled and assessed for potential confounders: age, NYHA class, left ventricular ejection fraction, coexistent valvular heart disease and right ventricular (RV) systolic pressure. Average diameter of the vena contracta (VCavg), effective regurgitant orifice area (EROA), regurgitant volume (RVol) and regurgitant fraction (RF) were obtained to grade TR severity. Median follow-up was 47 (17-80) months. The primary composite endpoint was the occurrence of death of any cause or hospitalization for right heart failure (RHF). Survival curves for the composite endpoint were divided in quartiles at median follow-up. Cut-off values for the echo parameters were derived to grade mild (below the 1st quartile), moderate (between 1st and 3rd quartiles), and severe (above the 3r quartile) TR. Results 33 deaths and 72 hospitalizations for RHF occurred. Event-free rate from death or RHF at the end of follow-up was 14%, 46% and 93% in pts with severe, moderate, and mild TR, respectively. Differences reached statistical significance early (at 1 month), and lasted during the whole follow-up period (Figure). The new threshold values for mild, moderate and severe TR are summarized in Table. Conclusions Partition values of quantitative echo-Doppler parameters used to grade mild, moderate and severe TR according to pts’ clinical outcome are significantly lower than those currently reported in guidelines. Further studies are needed to test if these new threshold values for severe TR will translate in earlier referral of pts to valve repair and improved prognosis. Mild Moderate Severe VCavg <3 mm 3-6 mm >6 mm EROA <0.15 cm² 0.15-0.30 cm² >0.30 cm² R Vol <15 ml 15-30 ml >30 ml RF <25% 25-45% >45% Abstract 38 Figure.
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Van Hulle, Suzanne, Issaka Sagara, Momar Mbodji, Ghislain Ismael Nana, Mamadou Coulibaly, Alassane Dicko, Mamady Kone et al. "Evaluation of the protective efficacy of a spatial repellent to reduce malaria incidence in children in Mali compared to placebo: study protocol for a cluster-randomized double-blinded control trial (the AEGIS program)". Trials 23, n.º 1 (5 de abril de 2022). http://dx.doi.org/10.1186/s13063-022-06197-w.
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Abstract Background Spatial repellents have been widely used for the prevention of mosquito bites but their efficacy in reducing mosquito-borne diseases has never been evaluated in Africa. Additionally, spatial repellents have the potential of being critical tools in the prevention of mosquito-borne diseases in contexts where typical vectors control efforts such as insecticide-treated nets (ITNs) and indoor residual spray (IRS) are inaccessible or underutilized such as among displaced populations or in emergency relief settings. To address this knowledge gap, Kolondieba District, Sikasso Region, Mali was selected as a site to estimate the impact of the Mosquito Shield™, a spatial repellent that incorporates transfluthrin on a plastic sheet, on malaria-related outcomes. Over the past decade, the Region of Sikasso, Health districts of Kadiolo, Yorosso, and Kolondieba have remained among the most afflicted, characterized by an annual parasite incidence of more than 116 cases per 1000 population [1] and a Plasmodium falciparum prevalence rate of 29.7% [2]. Methods Cluster-randomized, placebo-controlled, double-blinded clinical trial, whereby children ≥ 6 months to < 10 years old will be enrolled and followed to determine the time to malaria infection with monthly blood samples for microscopic diagnosis. A total of 1920 subjects (HHs) will be enrolled in 60 clusters (30 spatial repellent, 30 placebo). Malaria incidence will be estimated and compared to demonstrate and quantify the protective efficacy (PE) of a spatial repellent, in reducing malaria infection. Monthly mosquito collections using CDC light traps will be conducted to determine if there are entomological correlates of spatial repellent efficacy that may be useful for the evaluation of new spatial repellents. Quarterly human landing catches (HLC) will assess the behavioral effects of the intervention. Discussion Findings will serve as an efficacy trial of spatial repellent products for sub-Saharan Africa. Findings will be submitted to the World Health Organization Vector Control Advisory Group (WHO VCAG) for assessment of whether spatial repellents have “public health value.” Entomological outcomes will also be measured as proxies of malaria transmission to help develop guidelines for the evaluation of future spatial repellent products. Trial registration ClinicalTrials.govNCT04795648. Registered on March 12, 2021.
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N’Guessan, Raphael, Serge-Brice Assi, Alphonsine Koffi, Phamien Ludovic Ahoua Alou, Anatole Mian, Nicole L. Achee, Benedicte Fustec et al. "EaveTubes for control of vector-borne diseases in Côte d’Ivoire: study protocol for a cluster randomized controlled trial". Trials 24, n.º 1 (2 de novembro de 2023). http://dx.doi.org/10.1186/s13063-023-07639-9.
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Abstract Background Vector control tools, long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), have significantly contributed to malaria prevention efforts in sub-Saharan Africa. However, insecticide resistance has seriously hampered their efficacy in recent years and new tools are essential to further progress. In2Care® EaveTubes (ETs) are an inexpensive, new resistance-breaking vector control product under World Health Organization (WHO) evaluation informed by mosquito ecology to efficiently target malaria vectors. By installing ETs in the walls of the house at the eave level that funnel the natural airflow, mosquitoes are drawn in by the same heat and odor cues that typically attract them through open eaves. Once inside an ET, mosquitoes are exposed to insecticide-treated netting placed inside the ET. The aim of this study is to test whether ETs as stand-alone tool have an effect on the epidemiology of malaria in villages where houses have been modified with the ET intervention. Methods A two-armed, cluster randomized controlled trial will be conducted to evaluate the effect of ETs on clinical malaria incidence in children living in Côte d’Ivoire. Thirty-four villages will be selected based on population size and the proportion of houses suitable for modification with ETs (17 treatment arms (ETs + LLINs, 17 control arms (LLINs only)). Based on the population census, 55 households per cluster with eligible children (i.e., between the ages of 6 months to 8 years old at the start of the study) will be randomly selected for recruitment into the active detection cohorts. In the treatment arm, we will enroll eligible children who reside in ET-treated houses. The intervention and control cohorts will be followed for 4 months for baseline covariate measurements and 24 months with intervention. During case detection visits, blood samples will be taken from all febrile children and tested for malaria infection with rapid diagnostic tests (RDTs). All positive clinical malaria infections will be treated. To estimate the impact of the ET on malaria vector densities, entomological measurements (indoor sampling with CDC traps) will be conducted monthly in 20 clusters (10 ET, 10 Control) in 10 randomly selected households per cluster. To estimate the infectiousness of malaria vectors, sporozoite rates will be measured in subsets of the collected mosquito samples. Discussion Findings will serve as an efficacy trial of ETs and will be submitted to the WHO Vector Control Advisory Group (VCAG) for assessment of public health value. Entomological outcomes will also be measured as proxies of malaria transmission to help develop guidelines for the evaluation of future In2Care® ETs products. Trial registration ClinicalTrials.gov NCT05736679. Registered on 10 February 2023.