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Artigos de revistas sobre o tema "Uchikoza"

Autor: Grafiati

Publicado: 25 de julho de 2024

Última modificação: 31 de julho de 2024

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1

Suwarli, Suwarli. "Pengaruh metode uchikomi dan flexibility terhadap hasil bantingan pada pejudo Daerah Istimewa Yogyakarta". Jurnal Keolahragaan 4, n.º 1 (28 de abril de 2016): 47. http://dx.doi.org/10.21831/jk.v4i1.8135.

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Penelitian bertujuan mengetahui: (1) perbedaan pengaruh antara metode uchikomi dengan menggunakan karet ban sepeda dan uchikomi jalan terhadap hasil bantingan judo, (2) perbedaan hasil bantingan antara pejudo yang memiliki flexibility tinggi dan flexibility rendah, dan (3) interaksi antara metode uchikomi dan flexibility terhadap hasil bantingan judo. Metode penelitian adalah eksperimen dengan rancangan faktorial 2 x 2. Populasi penelitian adalah pejudo D.I. Yogyakarta yang berjumlah 44 pejudo. Sampel penelitian ini 24 pejudo yang diambil dengan teknik Purposive Rondom Sampling. Data penelitian ini diperoleh melalui tes dan pengukuran. Instrumen penelitian adalah sit and reach dan Randori (dipertandingkan) selama tiga menit. Teknik analisis data menggunakan ANAVA. Hasil penelitian bahwa: (1) ada perbedaan pengaruh yang signifikan antara latihan uchikomi dengan menggunakan karet ban sepeda dan uchikomi jalan terhadap hasil bantingan judo, (2) ada perbedaan yang signifikan hasil bantingan judo antara pejudo yang memiliki flexibility tinggi dan flexibility rendah, dan (3) ada interaksi antara metode uchikomi dan flexibility terhadap hasil bantingan judo.Kata Kunci: Metode latihan uchikomi, flexibility, judo, hasil bantingan judo. The effect of uchikomi method and flexibility against dings results among judoka D.I YogyakartaAbstractThis study aimed to determine: (1) the difference between the effect of uchikomi method using rubber tires and on the road uchikomi dings judo results, (2) the difference between the results dings among judoka which have high flexibility and low flexibility, and (3) the interaction between uchikomi method and flexibility of the dings results. This research is experimental with 2 x 2 factorial design. The population was judoka D.I. Yogyakarta, amounting to 44 judokas. The 24 samples were taken with random purposive sampling. All were data obtained through this study to test and measure the flexibility using the sit and reach test and the results of the Randori judo dings (contested) for three minutes. The data analysis technique used is the variant analysis ANOVA. The results of this study indicate that: (1) there is a significant difference between uchikomi exercises using a bicycle tire rubber and on the road uchikomi dings judo results, (2) there is a significant difference between the results of dings judo judoka which have high flexibility and low flexibility, and (3) there is an interaction between uchikomi method and flexibility against dings judo results.Keywords: Uchikomi method exercise, flexibility, judo, judo slam result

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Andalas, Hoesana Dian Dewi, e Sugeng Purwanto. "Pengaruh latihan uchikomi osaekomi dan power lengan terhadap hasil osaekomi saat randori pada pejudo". Jorpres (Jurnal Olahraga Prestasi) 15, n.º 1 (11 de julho de 2019): 1–13. http://dx.doi.org/10.21831/jorpres.v15i1.26026.

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Penelitian ini bertujuan untuk mengetahui: (1) perbedaan pengaruh antara metode uchikomi osaekomi berpasangan dan uchikomi bayangan terhadap hasil osaekomi saat randori, (2) perbedaan hasil osaekomi antara pejudo power lengan kuat dan power lengan lemah, (3) interaksi antara metode uchikomi osaekomi dan power lengan terhadap hasil osaekomi saat randori. Metode menggunakan eksperimen dengan rancangan faktorial 2 x 2. Populasi penelitian pejudo Daerah Istimewa Yogyakarta 44 pejudo. Sampel 24 pejudo dengan teknik purposive random sampling. Seluruh data diperoleh melalui tes power lengan dengan tes push up serta hasil osaekomi dengan randori selama empat menit. Teknik analisis data adalah ANAVA. Hasil penelitian menunjukkan: (1) ada perbedaan pengaruh yang signifikan antara latihan uchikomi dengan berpasangan dan uchikomi bayangan terhadap hasil osaekomi, (2) ada perbedaan yang signifikan hasil osaekomi antara pejudo yang memiliki power lengan kuat dan power lengan lemah, dan (3) ada interaksi antara metode uchikomi dan power lengan terhadap hasil osaekomi saat randori. The effects of the exercise of uchikomi osaekomi and power arm on osaekomi results when randori judoka AbstractThis research aims to find out: (1) the difference between the methods of uchikomi osaekomi effects in pairs and uchikomi shadow on the results of the current osaekomi randori, (2) the difference between the results of osaekomi judoka arm which has high power and low power arm, and (3) the interaction between the method of uchikomi osaekomi and power arm on the results when below randori osaekomi. This research is the experimental method with 2 x 2 factorial design. The research population was Judoka Special Region of Yogyakarta. amounting to 44 Judoka. The Sampel of this research were 24 Judoka taken with random purposive sampling technique. All data of this research was obtained through tests and measurements of arm power by using the push-up test and the results of osaekomi Randori (contested) for four minutes. The data analysis technique used is the Variant Analysis (ANAVA). The results show that: (1) there is a significant difference between the exercise of uchikomi by twos and shadow uchikomi on osaekomi results, (2) there is a significant difference between the results of osaekomi judo Judoka who have power high arm and lower arm power, and (3) there is an interaction between the method of uchikomi and power arm on the results of osaekomi while randori.

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3

Almansba, R., S. Sterkowicz, K. Sterkowicz-Przybycień e A. S. Comtois. "Reliability of the Uchikomi Fitness Test: A Pilot study. Reliability of the Uchikomi Fitness Test". Science & Sports 27, n.º 2 (abril de 2012): 115–18. http://dx.doi.org/10.1016/j.scispo.2011.09.001.

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Kurniawan, Candra, Sugiharto Sugiharto e Surisman Surisman. "The Effect of Uchikomi Seoi-Nage Exercise Using Kettler Rubber for 8 Weeks on Performance Physical Ability Judoka". Jp.jok (Jurnal Pendidikan Jasmani, Olahraga dan Kesehatan) 5, n.º 2 (30 de maio de 2022): 253–63. http://dx.doi.org/10.33503/jp.jok.v5i2.1803.

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This study aimed to analyze the effect of uchikomi movement exercise using kettler rubber to improve male judoka's physical abilities. This study uses an experimental method. A total of 22 male judoka participated as study samples and were randomly divided into two groups. The experimental group (21.8±1.78 years, 1.70±0.06 m, 71.1±13.5 kg) and control group (21.4±2.30 years, 1.72±0.05 m, 67.4±7.76 kg). The exercise program was carried out for 8 weeks with a frequency of 3 times/week. After warming up and before core judo training, the experimental group was treated with uchikomi movement training using kettler rubber. Meanwhile, the control group continued regular judo training. The statistical analysis procedure used an ANOVA test to determine the difference and comparison of pre-test and post-test mean values in experimental and control groups with a significance level (p<0.05). The results showed that parameter difference in the average value of experimental and control groups was significant on the performance of leg power and VO2Max endurance. In comparison, no significant differences occur in handgrip strength, flexibility, and speed. This study concludes that uchikomi seoi-nage movement exercise using a Kettler rubber produces changes in the performance of judoka physical abilities. However, a significant difference occurred in the performance of leg power and VO2Max endurance

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Bohomol, Elena. "Impacto dos estudos da professora Kazuko". Revista SOBECC 24, n.º 1 (10 de abril de 2019): 4. http://dx.doi.org/10.5327/10.5327/z1414-4425201900010002.

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Comentários sobre o artigo de revisão, de autoria da Profª Drª. Eliana Auxiliadora Magalhães Costa, intitulado “Reprocessamento de Produtos: Estado da arte à luz dos estudos de Kazuko Uchikawa Graziano”, publicado na última edição da Rev. SOBECC [2018;23(3):143-154].

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BOCHKOV, ANDRE V. "Mites of the subgenus Microtimyobia (Acariformes: Myobiidae: Radfordia) and their host-parasite relationships with cricetid rodents (Cricetidae)". Zootaxa 2954, n.º 1 (8 de julho de 2011): 1. http://dx.doi.org/10.11646/zootaxa.2954.1.1.

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Myobiid mites of the subgenus Radfordia (Microtimyobia) (Acariformes: Myobiidae) associated with hosts of the subfamilies Arvicolinae and Cricetinae (Cricetidae) are revised. Three new species are described from voles: R. (M.) dinaromys sp. nov. from Dinaromys bogdanovi from Montenegro, R. (M.) golenishchevi sp. nov. from Eothenomys wardi from China (Mekong River), and R. (M.) pitymys sp. nov. from Microtus pinetorum from USA (Virginia). Radfordia (M.) lemnina micromys Fain and Lukoschus, 1976 syn. nov., R. (M.) lemnina mikado Uchikawa et al., 1997 syn. nov., R. (M.) stekolnikovi Bochkov and Mironov, 1998 syn. nov., and R. (M.) stenocrani Bochkov and Mironov, 1998 syn. nov. are synonymized with R. (M.) lemnina (Koch, 1941); R. (M.) rutila Fain and Lukoschus, 1977 syn. nov. and R. (M.) lemnina hata Uchikawa et al., 1997 syn. nov. are synonymized with R. clethrionomys Fain and Lukoschus, 1977; R. (M.) lemnina japonica Uchikawa et al., 1997 syn. nov. is synonymized with R. (M.) rufocani Bochkov, 1995; R. (M.) macdonaldi Gill and Strandtmann, 1977 syn. nov. is synonymized with R. (M.) arctica Fain and Lukoschus, 1977; R. (M.) cricetulus pakistanensis Fain and Hyland, 1980 syn. nov. is synonymized with R. (M.) cricetulus Fain, 1973. The female and male keys to all 21 currently recognized Microtimyobia spp. are provided. The host distribution of Microtimyobia spp. is analyzed. These mites serve as peculiar “markers” of particular host groupings and in many cases are useful tools to test some controversial hypotheses of cricetid phylogeny, including the intriguing problem of phylogenetic relationships of the Palearctic and Nearctic voles of the genus Microtus.

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SASAKAWA, Yukihiro, e Taichi TEBAKARI. "Numerical Simulation for Saltwater Intrusion in the Western Uchikawa River". JOURNAL OF JAPAN SOCIETY OF HYDROLOGY AND WATER RESOURCES 29, n.º 4 (2016): 251–58. http://dx.doi.org/10.3178/jjshwr.29.251.

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TEBAKARI, Taichi. "HYDRAULIC CHARACTERISTICS IN TIDAL AREA OF THE UCHIKAWA RIVER DURING SALINITY INTRUSION". Journal of Japan Society of Civil Engineers, Ser. B1 (Hydraulic Engineering) 68, n.º 4 (2012): I_1327—I_1332. http://dx.doi.org/10.2208/jscejhe.68.i_1327.

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9

Neilson, Robert M. "Review of: “ Cement Technology ” Edited by E. M. Gartner and H. Uchikawa". Materials and Manufacturing Processes 11, n.º 2 (março de 1996): 319–20. http://dx.doi.org/10.1080/10426919608947486.

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10

Chr.Uchikova, Ekaterina. "Uchikova et al. Chondrosarcoma of the uterus. Acta Obstetricia et Gynecologica Scandinavica 2004; 83(7): 686-8". Acta Obstetricia et Gynecologica Scandinavica 84, n.º 5 (12 de abril de 2005): 496–97. http://dx.doi.org/10.1111/j.0001-6349.2005.0746b.x.

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11

Magalhães Costa, Eliana Auxiliadora. "Reprocessamento de produtos: estado da arte à luz dos estudos de Kazuko Uchikawa Graziano". Revista SOBECC 23, n.º 3 (30 de agosto de 2018): 142–54. http://dx.doi.org/10.5327/z1414-4425201800030006.

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Objetivo: Revisar o estado da arte sobre reprocessamento de produtos à luz dos estudos da Professora Kazuko Graziano. Método: Revisão integrativade literatura, tendo como descritor o nome da autora e com a seleção de 34 artigos. Resultados: Os estudos são abrangentes, majoritariamenteexperimentais e perpassaram pelos processos de limpeza e enxágue, desinfecção, esterilização e acondicionamento de artigos processados e em áreasemblemáticas para o reúso de materiais como ortopedia, oftalmologia, endoscopia e cirurgias videoassistidas. Conclusão: As evidências científicas dessesestudos são valorosas para o campo do reúso de produtos e para a qualidade e a segurança da prática assistencial na medida em que clarificam dúvidas esubsidiam mudanças de atitudesprocessos de trabalho. Esses estudos contribuem, também, para o controle sanitário de serviços de saúde ao subsidiar asVigilâncias Sanitárias com aportes teóricos sobre risco em reprocessamento de produtos e a Agência Nacional de Vigilância Sanitária (ANVISA) na atualizaçãoda política nacional de reúso de produtos para saúde (PPS) do país.

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12

HASEGAWA, Hirohiko. "Glacial Geomorphology and Late Pleistocene Glacial Fluctuations in the Uchikomi Valley, Northern Japanese Alps". Geographical Review of Japa,. Ser. A, Chirigaku Hyoron 65, n.º 4 (1992): 320–38. http://dx.doi.org/10.4157/grj1984a.65.4_320.

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13

Domrow, R. "Acari prostigmata (excluding Trombiculidae) parasitic on Australian vertebrates: an annotated checklist, keys and bibliography". Invertebrate Systematics 4, n.º 6 (1990): 1283. http://dx.doi.org/10.1071/it9901283.

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The prostigmatic mites (excluding Trombiculidae) parasitic on, or associated with, Australian vertebrates are reviewed, and keys and illustrations are provided to enable separation of all 45 genera and 121 species recognised. Two new species are described: Paraspeleognathopsis exaeta sp. nov. (Erynetidae), from the nasal passages of the marsupial Petaurus breviceps in New South Wales, and Radfordia hydromys Fain sp. nov. (Myobiidae). New synonymy in Ereynetidae: Boydaia Womersley, 1953 = Coboydaia Fain, 1971b; Neospeleognathopsis Fain, 1958b = Pteropignathus Fain & Lukoschus, 1979b; Psittaboydaia Fain, 1985 = Trichoglossiella Fain, 1985; in Myobiidae: Australomyobia dasycercus Fain, 1973a = A. d. antechinus Fain & Lukoschus, 1979d; Calcarmyobia miniopteris (Womersley, 1941a) = C. o. orianae Uchikawa, 1985c; Ewingana bispinosa Radford, 1948 = E. b. longispina Fain & Lukoschus, 1979c; Radfordia Ewing, 1938 = Pseudoradfordia Dubinin, 1957a = Syconycterobia Fain, 1973b; in Demodecidae: Demodex equi Railliet, 1893 = D. caballi Desch & Nutting, 1979a; D. ovis Railliet, 1893 = D. aries Desch, 1987; in Leeuwenhoekiidae: Odontacarus Ewing, 1929 = Leogonius Vercammen-Grandjean, 1968. A host-parasite list and bibliography are included.

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14

TEBAKARI, Taichi, Koji OKUGAWA, Masaki SAKAMOTO e Ikuko YASUDA. "A FUNDAMENTAL STUDY ON WATER ENVIRONMENT IN UCHIKAWA RIVER: COMPLICATED SYSTEM OF SEAWATER AND PURIFICATION WATER". Journal of Japan Society of Civil Engineers, Ser. B1 (Hydraulic Engineering) 67, n.º 4 (2011): I_1663—I_1668. http://dx.doi.org/10.2208/jscejhe.67.i_1663.

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SASAKAWA, Yukihiro, e Taichi TEBAKARI. "BACKFLOW PHENOMENON IN THE TIP OF SALT WEDGE IN TIDAL AREA OF THE NISHI-UCHIKAWA RIVER, TOYAMA". Journal of Japan Society of Civil Engineers, Ser. G (Environmental Research) 71, n.º 5 (2015): I_103—I_110. http://dx.doi.org/10.2208/jscejer.71.i_103.

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Yamashita, Daisuke, Shusaku Yoshikawa, Minoru Tsukagoshi, Shinji Nagaoka e Yasuhiro Kumahara. "Stratigraphy and Chronology of the Lower-Middle Pleistocene in the Ozu and Uchiko Basins". Quaternary Research (Daiyonki-Kenkyu) 45, n.º 6 (2006): 463–77. http://dx.doi.org/10.4116/jaqua.45.463.

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Tian, Yongjun, Kazuhisa Uchikawa, Yuji Ueda e Jiahua Cheng. "Comparison of fluctuations in fish communities and trophic structures of ecosystems from three currents around Japan: synchronies and differences". ICES Journal of Marine Science 71, n.º 1 (14 de outubro de 2013): 19–34. http://dx.doi.org/10.1093/icesjms/fst169.

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Abstract Tian, Y., Uchikawa, K., Ueda, Y., and Cheng, J. Comparison of fluctuations in fish communities and trophic structures of ecosystems from three currents around Japan: synchronies and differences. – ICES Journal of Marine Science, 71: . Features of three marine ecosystems affected by the Tsushima (TWC), Kuroshio (KC), and Oyashio (OC) currents were analysed based on fishery, oceanographic, and climate datasets during 1955–2010. Principal component (PC) analysis for catches of 25 indicator species showed evident decadal variation patterns with a step change in the first principal component (PC1) in the late 1980s, indicating synchronies in the dominant variation mode across the ecosystems. Step changes were also detected in the mid-1970s in PC2 and PC3 in OC, and around 1970 in PCs in KC and TWC. These indicate that the most marked change across the ecosystems occurred in the late 1980s, corresponding to the late 1980s climate regime shift, but OC also responded strongly to the mid-1970s regime shift, indicating different responses to regime shifts. The generalized additive model showed the PCs associated largely with water temperature in each region as well as climate indices, indicating the importance of regional oceanographic conditions. Ecosystem indicators such as the mean trophic level showed similarities between TWC and KC but differences with OC, indicating that trophic structures in TWC and KC were largely dependent on the mid-trophic (small pelagic species) level, while on demersal species in OC.

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AKIMOTO, Kazuhide, e Terukazu TAKESHITA. "STRUCTURE OF SPACE ON TOWN HOUSE OF TOWN IN VILLAGE YOUKAICHI IN UCHIKO FROM VIEW OF LOCATION". Journal of Architecture and Planning (Transactions of AIJ) 63, n.º 505 (1998): 59–66. http://dx.doi.org/10.3130/aija.63.59_1.

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MASUCHI, Katsuyuki, Shin NORIKANE, Daiki OGURA, Yuki KUBOTA e Takashi MATSUI. "Exploring of optimum paces of uchikomi (repetition training) for foot techniques aimed at enhancing the endurance capacity of collegiate male judo athletes". Taiikugaku kenkyu (Japan Journal of Physical Education, Health and Sport Sciences) 65 (2020): 793–804. http://dx.doi.org/10.5432/jjpehss.20032.

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AKIMOTO, Kazuhide, e Terukazu TAKESHITA. "SPATIAL COMPOSITION OF YOUKAICHI AND MUIKAICHI IN UCHIKO FROM THE VIEWPOINT OF MODIFICATIONS OF THE HOUSING SITE'S DEPTH". Journal of Architecture and Planning (Transactions of AIJ) 65, n.º 527 (2000): 99–106. http://dx.doi.org/10.3130/aija.65.99_1.

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Nishio-Hamane, Daisuke, Takahiro Tanaka e Tetsuo Minakawa. "Aurihydrargyrumite, a Natural Au6Hg5 Phase from Japan". Minerals 8, n.º 9 (19 de setembro de 2018): 415. http://dx.doi.org/10.3390/min8090415.

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Aurihydrargyrumite, a natural Au6Hg5 phase, was found in Iyoki, Uchiko, Ehime Prefecture, Shikoku Island, Japan. Aurihydrargyrumite with a metallic silver luster occurs as a submicron- to 2 μm-thick layer on the outermost surface of the placer gold. A prismatic face may be formed by {001} and {100} or {110}. The streak is also silver white and its Mohs hardness value is ca. 2.5. Its tenacity is ductile and malleable, and its density, as calculated based on the empirical formula and powder unit-cell data, is 16.86 g·cm−3. The empirical formula of aurihydrargyrumite, on the basis of 11 Au + Hg, is Au5.95Hg5.05. Aurihydrargyrumite is hexagonal, P63/mcm, with the lattice parameters a = 6.9960(10) Å, c = 10.154(2) Å and V = 430.40(15) Å3, which is identical with the synthetic Au6Hg5 phase. The seven strongest lines in the powder X-ray diffraction (XRD) pattern [d in Å(I/I0)(hkl)] were 2.877(29)(112), 2.434(42)(113), 2.337(100)(104), 2.234(87)(211), 1.401(39)(314), 1.301(41)(404), and 1.225(65)(217). Aurihydrargyrumite forms through the weathering of mercury-bearing placer gold by involvement of self-electrorefining. This new mineral has been approved by the IMA-CNMNC (2017-003) and it is named for its composition, being a natural amalgam of gold (Latin: aurum) and mercury (Latin: hydrargyrum).

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Shiraishi, Masayuki, e Abdul Razaq . "The Role of Farmers Market and Discussion Groups in Developing Agricultural Marketing System in Uchiko Town of Ehime Prefecture, Japan". Journal of Applied Sciences 5, n.º 4 (15 de março de 2005): 753–60. http://dx.doi.org/10.3923/jas.2005.753.760.

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Birdsall, Blair. "Discussion of “ Advanced Fabrication and Erection Techniques for Long Suspension Bridge Cables ” by Minora Matsuzaki, Chihiko Uchikawa, and Takeshi Mitamura (March, 1990, Vol. 116, No. 1)". Journal of Construction Engineering and Management 118, n.º 1 (março de 1992): 200–205. http://dx.doi.org/10.1061/(asce)0733-9364(1992)118:1(200).

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Chatterji, S. "A discussion of the paper “the role of steric repulsive force in the dispersion of cement particles in fresh paste prepared with organic admixture” by H. Uchikawa et al". Cement and Concrete Research 27, n.º 9 (setembro de 1997): 1451–52. http://dx.doi.org/10.1016/s0008-8846(97)00131-2.

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Bensted, John. "A discussion of the paper “influence of CaSO42H2O, CaSO4 1/2H2O and CaSO4 on the initial hydration of clinker having different burning degrees” by H. Uchikawa, S. Uchida, K. Ogawa and S. Hanehara". Cement and Concrete Research 15, n.º 4 (julho de 1985): 735–36. http://dx.doi.org/10.1016/0008-8846(85)90077-8.

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Laura, P. A. A. "Discussion: “Use of a Boundary-Fitted Coordinate Transformation for Unsteady Heat Conduction Problems in Multiconnected Regions With Arbitrarily Shaped Boundaries” (Uchikawa, S., and Takeda, R., 1985, ASME J. Heat Transfer, 107, pp. 494–498)". Journal of Heat Transfer 108, n.º 3 (1 de agosto de 1986): 715. http://dx.doi.org/10.1115/1.3247003.

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Uchikawa, Ryo, Kazuya Takakuwa, Hirofumi Mikami, Shoichi Metsugi, Kenji Taniguchi, Yoshinori Narita e Mika Kamata-Sakurai. "Abstract 5518: Single cell RNA sequencing revealed that the mechanism of the synergistic efficacy of STA551 and immune checkpoint inhibitor results from the induction of highly activated T cells in tumor". Cancer Research 82, n.º 12_Supplement (15 de junho de 2022): 5518. http://dx.doi.org/10.1158/1538-7445.am2022-5518.

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Abstract Background: CD137 (4-1BB) is a co-stimulatory molecule which exerts activation signals in multiple immune cell subsets. However, agonist antibodies targeting CD137 have not been clinically successful due to severe systemic toxicity. Therefore, we generated STA551, a tumor selective CD137 agonist antibody. STA551 binds to CD137 only in the presence of ATP, which is known to be present at high levels in tumor tissue, and activates immune cells such as T cells. Previous studies have shown that STA551 exhibits antitumor efficacy without inducing a systemic immune response in a murine model. Combination studies with anti-PD-L1 antibody have also shown synergistic efficacy without inducing a systemic immune response. However, it was unclear why they exhibit strong combination effects. In this study, we elucidated the mechanism of STA551 and anti-PD-L1 antibody efficacy through comprehensive analysis of gene expression using single cell RNA sequencing. Method & Result: In a colon 38-bearing human CD137 knock-in mouse model, combination therapy with STA551 and anti-PD-L1 antibody showed potent anti-tumor efficacy. From immunohistochemistry of tumor tissue, increased numbers of CD8+ T cells and elevated expression of PD-L1 molecules were observed. To perform a detailed mechanistic analysis, tumor tissue was collected after antibody administration and CD3 positive and CD3 negative fractions were separated and gene expression was comprehensively analyzed using single cell RNA-seq. Next, the fraction expressing Cd8a gene was extracted from CD3 positive fraction and clustered. One cluster was found to be markedly increased in STA551 and anti-PD-L1 antibody combination compared to vehicle or monotherapy treatment. Differential gene expression analysis revealed that the cluster was enriched for genes related to cytokines and chemokines. This result revealed that the combination of STA551 and anti-PD-L1 antibody induced highly activated CD8+T cells. Conclusion: The combination of STA551 and PD-L1 showed synergistic anti-tumor efficacy in a colon38-bearing human CD137 knock-in mouse model. Detailed mechanistic analysis showed that the combination of STA551 and PD-L1 induced highly activated CD8+T cells expressing chemokines and cytokines compared to monotherapy. This cluster also express chemokines, suggesting that other immune cells have been recruited. These results suggest that even the activation of only tumor tissue, which is a characteristic of STA551, can induce a strong immune response. Citation Format: Ryo Uchikawa, Kazuya Takakuwa, Hirofumi Mikami, Shoichi Metsugi, Kenji Taniguchi, Yoshinori Narita, Mika Kamata-Sakurai. Single cell RNA sequencing revealed that the mechanism of the synergistic efficacy of STA551 and immune checkpoint inhibitor results from the induction of highly activated T cells in tumor [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5518.

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Yoshimoto, Moe, Naoki Kimura, Takayuki Kamikawa, Shinya Ishii, Masaru Muraoka, Kenji Taniguchi, Ryo Uchikawa et al. "Abstract 1239: SAIL66, a next generation T cell engager targeting CLDN6, potentiates efficacy by binding to CD3/CD137". Cancer Research 84, n.º 6_Supplement (22 de março de 2024): 1239. http://dx.doi.org/10.1158/1538-7445.am2024-1239.

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Abstract Background: Claudin-6 (CLDN6), one of over 20 known human CLDN family members, is upregulated in many solid tumors but shows minimal or no expression in healthy adult tissues. This makes it an ideal target for cancer therapy. Although several therapeutic modalities targeting CLDN6 are currently under investigation—including T cell engagers (TCE), CAR-T, and antibody drug conjugates—a more potent therapeutic option is still desirable. TCEs are a promising avenue within cancer immunotherapy, but their current efficacy and safety must be improved, particularly against solid tumors. Methods and Results: To enhance immune activation and achieve successful clinical outcomes against solid tumors expressing CLDN6, we generated SAIL66, a CLDN6-targeting next generation TCE, using a new technological format called Dual-Ig®. SAIL66 is a tri-specific monoclonal antibody designed to bind to CLDN6 on cancer cells with one Fab arm and to both CD3 and CD137 with the other Fab arm. The preclinical characterization of SAIL66 was performed in a series of in vitro and in vivo studies which included comparisons to a conventional TCE targeting CLDN6 and CD3. SAIL66 demonstrated high specificity for CLDN6 despite its similarity to CLDN3, CLDN4, and CLDN9, suggesting a lack of off-target toxicity in patients. Using a Jurkat cell system harboring NFAT or NF-κB reporter genes, we confirmed that SAIL66 exerts CD3 and CD137 signal induction activity depending on CLDN6 expression. SAIL66 induced activation of T cells, release of cytokines, and lysis of CLDN6-positive cancer cells. In vivo studies with a humanized mouse (huNOG) model showed that SAIL66 had better anti-tumor efficacy in eliminating CLDN6-positive cancer cells than a conventional TCE. Flow cytometry analysis in the huNOG model revealed that SAIL66 also more significantly increased CD3+ T cell infiltration of tumor tissue and resulted in a smaller percentage of exhausted T cells in tumor. Moreover, transcriptome analysis in the huNOG model showed that both SAIL66 and the conventional TCE increase expression of genes associated with immune activation, with a durable increase observed especially with SAIL66. Further, we clarified that T cells repeatedly stimulated with SAIL66 had a greater ability to inhibit the growth of CLDN6-positive cancer cells than T cells stimulated with the conventional TCE in vitro. Conclusion and Discussion: Our study shows that SAIL66 has better anti-tumor efficacy against CLDN6-positive cancer cells than a conventional TCE. This is due to effective immune activation by SAIL66 which triggers CD3 signaling (signal 1) combined with CD137 co-stimulatory signaling (signal 2) in T cells. Thus, SAIL66 represents a promising therapeutic option for solid tumors expressing CLDN6. A clinical trial for CLDN6-positive cancer patient is now ongoing (NCT05735366). Citation Format: Moe Yoshimoto, Naoki Kimura, Takayuki Kamikawa, Shinya Ishii, Masaru Muraoka, Kenji Taniguchi, Ryo Uchikawa, Momoko Okuda-Miura, Sho Akai, Tatsushi Kodama, Hirofumi Sakumoto, Shigeto Kawai, Mei Shimada, Mika Kamata-Sakurai, Hiroyuki Aburatani, Takehisa Kitazawa, Tomoyuki Igawa. SAIL66, a next generation T cell engager targeting CLDN6, potentiates efficacy by binding to CD3/CD137 [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 1239.

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Maultzsch, M. "Cement technology. Ed. byE. M. Gartner andH. Uchikawa. Ceramic transactions, Vol. 40, 299 pp., The American Ceramic Society, Westerville, Ohio, 1994, £ 75.00, ISBN 0-944904-72-6. In Europa zu beziehen durch: American Technical Publishers Ltd, 27-29 Knowl Piece, SG4 OSX, England". Materials and Corrosion/Werkstoffe und Korrosion 46, n.º 8 (agosto de 1995): 499–500. http://dx.doi.org/10.1002/maco.19950460816.

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Alvarez, Jon. "The Shift of the Valuation and Management Model in Japanese Protected Townscapes from a Tourism Point of View to a Local Community and Environment Point of View: Case Studies of Uchiko (1978-82), Kurayoshi (1998) and Ine (2004-05)". Athens Journal of Architecture 4, n.º 4 (27 de setembro de 2018): 405–32. http://dx.doi.org/10.30958/aja.4-4-2.

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Ningrum,, Utari Widya, Awan Hariono, Rumpis Agus Sudarko e Ujang Nurdin. "The Effect of Training Model and Arm Muscle Strength on Arm Power in Judo Sport". INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH AND ANALYSIS 07, n.º 01 (23 de janeiro de 2024). http://dx.doi.org/10.47191/ijmra/v7-i01-30.

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The purpose of this study was to determine the effect of training models and arm muscle strength on arm power judo sports in Bandar Lampung City in order to determine whether there is an effect of training models and arm muscle strength on arm power in athletes. The type of research is factorial 2 x 2. The sample used was judo athletes in Bandar Lampung City totalling 50 athletes. The sampling technique used was purposive sampling. The instrument used was the Two Medicine Ball Put test. Data analysis techniques include descriptive analysis, prerequisite tests (normality and homogeneity tests), hypothesis testing using paired sample tests and independent sample tests. The data analysis technique used in this study using SPSS 20 is by using two-way ANOVA (two-way ANOVA). The results showed (1) There was a significant difference in influence between elastic training of Uchikomi tyres and push ups on arm power of judo athletes in Bandar Lampung City, with a p-value of 0.009 < 0.05. The Uchikomi elastic tyre training group was better than the push up group with an average posttest difference of 0.37 metres. (2) There is a significant difference between athletes with high and low arm muscle strength on arm power of judo athletes in Bandar Lampung City, with a p-value of 0.003 <0.05. Athletes with high arm muscle strength are better than athletes with low arm muscle strength with a posttest average difference of 0.44 metres. (3) There is a significant interaction between Uchikomi tyre elastic training and push ups and arm muscle strength (high and low) on arm power of judo athletes in Bandar Lampung City, with a p-value of 0.002 <0.05. The results showed that the Uchikomi tyre elastic training group was a more effective method used for athletes with high arm muscle strength and the push up group was more effective for athletes with low arm muscle strength.

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Najjar-Debbiny, Ronza, Naomi Gronich, Gabriel Weber, Johad Khoury, Lee Hilary Goldstein e Walid Saliba. "Reply to Chen et al; Uchikoba et al; Siberry et al; and Vuorio et al". Clinical Infectious Diseases, 17 de agosto de 2022. http://dx.doi.org/10.1093/cid/ciac668.

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Eken, Özgür, Fatma Hilal Yagin, Ismihan Eken, Tomasz Gabrys, Vera Knappova, Serdar Bayrakdaroglu, Zeki Akyildiz e Hadi Nobari. "Diurnal variation in Uchikomi fitness test performance: Influence of warm-up protocols". Frontiers in Psychology 13 (17 de novembro de 2022). http://dx.doi.org/10.3389/fpsyg.2022.1059727.

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Performance is judged using a variety of methods to ensure uniformity between competitions. Uchikomi Fitness Test (UFT) could accomplished between morning qualifying and evening finals. The purpose of this study is to investigate the impact of different warm-up protocols on UFT at different times of the day in female judokas. Ten volunteer women who had been practising judo on a regular basis for more than 5 years and actively competed in international tournaments took part in this study. Judokas completed UFT, either after no-warm-up (NWU), specific warm-up (SWU), and linear+lateral warm-up (FWU) protocols for two times a day in the morning: 09:00–11:00 and in the evening: 16:00–18:00, on non-consecutive days. In conclusion, there was a significant increase in UFT scores (F = 9.89; p = 0.002), a + b (F = 4.42; p = 0.04) and heart rate (F = 28.99; p < 0.001) in the early evening compared to the morning. Increases in UFT performance were observed in the SWU protocol compared to the NWU and FWU protocols (p < 0.05). However, the interaction between time of day and warm protocol was not significant (p > 0.05). The UFT performance revealed diurnal variation, and the judokas’ performances may be favourably affected more in the late hours, particularly following SWU procedures.

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"Life prediction of thermal fatigue for cylinder head Masashi Uchikura, Toshiharu Matsui (Mitsubishi Motors Corporation)". JSAE Review 17, n.º 4 (outubro de 1996): 442. http://dx.doi.org/10.1016/s0389-4304(96)80556-x.

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Nobori, Junichiro, Yoshihiro Miyake, Keiko Tanaka, Hidenori Senba, Masahiro Okada, Daiki Takagi, Masato Teraoka, Hiroyuki Yamada, Bunzo Matsuura e Naohito Hato. "Relationship between hearing loss and prevalence of depressive symptoms in Japan: baseline data from the Aidai Cohort Study in Yawatahama and Uchiko". Archives of Gerontology and Geriatrics, maio de 2022, 104735. http://dx.doi.org/10.1016/j.archger.2022.104735.

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Miyake, Yoshihiro, Keiko Tanaka, Chisato Nagata, Hidenori Senba, Yasuko Hasebe, Toyohisa Miyata, Takashi Higaki, Eizen Kimura, Bunzo Matsuura e Ryuichi Kawamoto. "Fish and Polyunsaturated Fatty Acid Intake and Carotid Intima-Media Thickness in Japan: the Aidai Cohort Study in Yawatahama, Uchiko, Seiyo, and Ainan". Journal of Atherosclerosis and Thrombosis, 2022. http://dx.doi.org/10.5551/jat.63781.

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Miyake, Yoshihiro, Keiko Tanaka, Hidenori Senba, Yasuko Hasebe, Toyohisa Miyata, Takashi Higaki, Eizen Kimura, Bunzo Matsuura e Ryuichi Kawamoto. "Education and household income and carotid intima-media thickness in Japan: baseline data from the Aidai Cohort Study in Yawatahama, Uchiko, Seiyo, and Ainan". Environmental Health and Preventive Medicine 26, n.º 1 (9 de setembro de 2021). http://dx.doi.org/10.1186/s12199-021-01011-6.

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Abstract Background Epidemiological evidence for the relationship between education and income and carotid intima-media thickness (CIMT) has been limited and inconsistent. The present cross-sectional study investigated this issue using baseline data from the Aidai Cohort Study. Methods Study subjects were 2012 Japanese men and women aged 34−88 years. Right and left CIMT were measured at the common carotid artery using an automated carotid ultrasonography device. Maximum CIMT was defined as the largest CIMT value in either the left or right common carotid artery. Carotid wall thickening was defined as a maximum CIMT value > 1.0 mm. Results The prevalence of carotid wall thickening was 13.0%. In participants under 60 years of age (n = 703) and in those aged 60 to 69 years (n = 837), neither education nor household income was associated with carotid wall thickening or with maximum CIMT. Among those aged 70 years or older (n = 472), however, higher educational level, but not household income, was independently related to a lower prevalence of carotid wall thickening: the multivariate-adjusted odds ratio for high vs. low educational level was 0.43 (95% confidence interval 0.21−0.83, p for trend = 0.01). A significant inverse association was observed between education, but not household income, and maximum CIMT (p for trend = 0.006). Conclusions Higher educational level may be associated with a lower prevalence of carotid wall thickening and a decrease in maximum CIMT only in participants aged 70 years or older.

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