Literatura científica selecionada sobre o tema "Targeted transcription regulation"
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Artigos de revistas sobre o assunto "Targeted transcription regulation"
Braun, Christian J., Peter M. Bruno, Max A. Horlbeck, Luke A. Gilbert, Jonathan S. Weissman e Michael T. Hemann. "Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation". Proceedings of the National Academy of Sciences 113, n.º 27 (20 de junho de 2016): E3892—E3900. http://dx.doi.org/10.1073/pnas.1600582113.
Texto completo da fonteLi, Conghui, Honghong Wang, Zhinang Yin, Pingping Fang, Ruijing Xiao, Ying Xiang, Wen Wang et al. "Ligand-induced native G-quadruplex stabilization impairs transcription initiation". Genome Research 31, n.º 9 (16 de agosto de 2021): 1546–60. http://dx.doi.org/10.1101/gr.275431.121.
Texto completo da fonteAhmed, Mahmoud, Trang Huyen Lai, Trang Minh Pham, Sahib Zada, Omar Elashkar, Jin Seok Hwang e Deok Ryong Kim. "Hierarchical regulation of autophagy during adipocyte differentiation". PLOS ONE 17, n.º 1 (26 de janeiro de 2022): e0250865. http://dx.doi.org/10.1371/journal.pone.0250865.
Texto completo da fonteScott, James N. F., Adam P. Kupinski e Joan Boyes. "Targeted genome regulation and modification using transcription activator-like effectors". FEBS Journal 281, n.º 20 (6 de setembro de 2014): 4583–97. http://dx.doi.org/10.1111/febs.12973.
Texto completo da fonteHuh, Hyunbin, Dong Kim, Han-Sol Jeong e Hyun Park. "Regulation of TEAD Transcription Factors in Cancer Biology". Cells 8, n.º 6 (17 de junho de 2019): 600. http://dx.doi.org/10.3390/cells8060600.
Texto completo da fonteUprety, Bhawana, Amala Kaja, Jannatul Ferdoush, Rwik Sen e Sukesh R. Bhaumik. "Regulation of Antisense Transcription by NuA4 Histone Acetyltransferase and Other Chromatin Regulatory Factors". Molecular and Cellular Biology 36, n.º 6 (11 de janeiro de 2016): 992–1006. http://dx.doi.org/10.1128/mcb.00808-15.
Texto completo da fontePerez-Oquendo, Mabel, e Don L. Gibbons. "Regulation of ZEB1 Function and Molecular Associations in Tumor Progression and Metastasis". Cancers 14, n.º 8 (7 de abril de 2022): 1864. http://dx.doi.org/10.3390/cancers14081864.
Texto completo da fonteImoberdorf, Rachel Maria, Irini Topalidou e Michel Strubin. "A Role for Gcn5-Mediated Global Histone Acetylation in Transcriptional Regulation". Molecular and Cellular Biology 26, n.º 5 (1 de março de 2006): 1610–16. http://dx.doi.org/10.1128/mcb.26.5.1610-1616.2006.
Texto completo da fonteNourani, Amine, Yannick Doyon, Rhea T. Utley, Stéphane Allard, William S. Lane e Jacques Côté. "Role of an ING1 Growth Regulator in Transcriptional Activation and Targeted Histone Acetylation by the NuA4 Complex". Molecular and Cellular Biology 21, n.º 22 (15 de novembro de 2001): 7629–40. http://dx.doi.org/10.1128/mcb.21.22.7629-7640.2001.
Texto completo da fonteZhang, Yixin, Yanlan Mo, Liyuan Han, Zhenyuan Sun e Wenzhong Xu. "Exploring Transcriptional Regulation of Hyperaccumulation in Sedum plumbizincicola through Integrated Transcriptome Analysis and CRISPR/Cas9 Technology". International Journal of Molecular Sciences 24, n.º 14 (24 de julho de 2023): 11845. http://dx.doi.org/10.3390/ijms241411845.
Texto completo da fonteTeses / dissertações sobre o assunto "Targeted transcription regulation"
Maeder, Morgan Lee. "Engineered DNA-Binding Proteins for Targeted Genome Editing and Gene Regulation". Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:10770.
Texto completo da fonteYi, Jia. "The Role of Convergent Transcription in Regulating Alternative Splicing : Targeted Epigenetic Modification via Repurposed CRISPR/Cas9 System and Its Impact on Alternative Splicing Modulation". Electronic Thesis or Diss., Sorbonne université, 2020. http://www.theses.fr/2020SORUS382.
Texto completo da fonteAlternative splicing of precursor RNA is a co-transcriptional process that affects the vast majority of human genes and contributes to protein diversity. Dysregulation of such process is implicated in various diseases, including tumorigenesis. However, the mechanisms regulating these processes were still to be characterized. In this study, we showed that perturbations of alternative splicing correlated with dysregulations of convergent transcription and DNA methylation. Convergent transcription could be generated between pairs of neighboring genes in opposite orientation, or between intragenic enhancers and their host gene. CENPO and ADCY3 was identified as a convergent transcription gene pair. We found, in a tumor progression model of breast cancer, that the splicing change of the ADCY3 variant exon22 correlated with an increase of its transcription that went against that of CENPO. By using targeted transcription repression system CRISPRi, we demonstrated that downregulating the transcription of CENPO could not reverse the alternative splicing alteration of ADCY3 in cancer cells (DCIS). An active intragenic enhancer was identified in the intron16 of CD44, at the downstream of its alternative exons. By using targeted transcription activation system CRISPRa, we showed that upregulating the transcription of CD44 could not alter the alternative splicing of CD44 in DCIS cells. These results suggest that convergent transcription modulation through changes of promoter activity does not alter the alternative splicing of ADCY3 and CD44 in DCIS cells. However, through replacing the intragenic enhancer by an inducible promoter, we found that intragenic transcription activation increased the inclusion level of several alternative exons of CD44 in HCT116 cells. This result suggested that local convergent transcription could have a direct impact on the alternative splicing of CD44. Furthermore, by using targeted DNA methylation system CRISPR/dCas9-DNMT3b, we showed that DNA methylation at variant exons could directly modify CD44 alternative splicing. This thesis work also explored the limitation and feasibility of studying alternative splicing with repurposed CRISPR systems
Carvin, Christopher Dumas. "Transcriptional regulation and chromatin remodeling mechanisms at PHO5". Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/2193.
Texto completo da fonteMARIANI, JESSICA. "Transcriptional regulation, target genes and functional roles of the SOX2 transcription factor in mouse neural stem cells maintenance and neuronal differentiation". Doctoral thesis, Università degli Studi di Milano-Bicocca, 2009. http://hdl.handle.net/10281/8321.
Texto completo da fonteZHAO, CHEN. "DECIPHERING TRANSCRIPTIONAL ACTIVITY OF DROSOPHILA BICOID MORPHOGEN: SELECTIVITY AND REGULATION". University of Cincinnati / OhioLINK, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1006196849.
Texto completo da fonteAkhmetova, Laila. "Transcriptional Regulation of Nodal Target Genes in Early Zebrafish Development". Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493493.
Texto completo da fonteBiology, Molecular and Cellular
Bolick, Sophia C. E. "Regulation of transcription and analysis of drug targets in lymphoma and myeloma cells". [Tampa, Fla] : University of South Florida, 2006. http://purl.fcla.edu/usf/dc/et/SFE0001750.
Texto completo da fonteMARKEY, MICHAEL PATRICK. "TRANSCRIPTIONAL REGULATION BY THE RETINOBLASTOMA TUMOR SUPPRESSOR: NOVEL TARGETS AND MECHANISMS". University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1092243630.
Texto completo da fonteMarkey, Michael P. "Transcriptional regulation by the retinoblastoma tumor suppressor novel targets and mechanisms /". Cincinnati, Ohio : University of Cincinnati, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=ucin1092243630.
Texto completo da fonteRatanamart, Jarupa. "Immunogenicity, efficiency and transcriptional regulation of plasmin-mediated muscle-targeted insulin gene therapy for diabetes". Thesis, University of Newcastle Upon Tyne, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431132.
Texto completo da fonteLivros sobre o assunto "Targeted transcription regulation"
Ho, Rita Sam Man. Disruption of imprinted transcription regulation of the Mash2 gene by targeted DNA insertion. 2004.
Encontre o texto completo da fonteCapítulos de livros sobre o assunto "Targeted transcription regulation"
Dixit, Vineeta, e Priti Upadhyay. "Targeted Genome-Editing Techniques in Plant Defense Regulation". In Transcription Factors for Biotic Stress Tolerance in Plants, 1–32. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-12990-2_1.
Texto completo da fonteWestermarck, Jukka. "Regulation of Transcription Factor Function by Targeted Protein Degradation: An Overview Focusing on p53, c-Myc, and c-Jun". In Methods in Molecular Biology, 31–36. Totowa, NJ: Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-738-9_2.
Texto completo da fonteKim, Sung-Il, Yogendra Bordiya, Ji-Chul Nam, José Mayorga e Hong-Gu Kang. "High-Throughput Targeted Transcriptional Profiling of Defense Genes Using RNA-Mediated Oligonucleotide Annealing, Selection, and Ligation with Next-Generation Sequencing in Arabidopsis". In Modeling Transcriptional Regulation, 227–52. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1534-8_15.
Texto completo da fonteBeach, Dale L., e Jack D. Keene. "Ribotrap: Targeted Purification of RNA-Specific RNPs from Cell Lysates Through Immunoaffinity Precipitation to Identify Regulatory Proteins and RNAs". In Post-Transcriptional Gene Regulation, 69–91. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-033-1_5.
Texto completo da fonteBrooks, Matthew D., Kelsey M. Reed, Gabriel Krouk, Gloria M. Coruzzi e Bastiaan O. R. Bargmann. "The TARGET System: Rapid Identification of Direct Targets of Transcription Factors by Gene Regulation in Plant Cells". In Transcription Factor Regulatory Networks, 1–12. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2815-7_1.
Texto completo da fonteWang, Chenguang, Jun-Yuan Ji, Lifeng Tian e Richard G. Pestell. "Transcriptional Regulation of Lipogenesis as a Therapeutic Target for Cancer Treatment". In Nuclear Signaling Pathways and Targeting Transcription in Cancer, 259–75. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8039-6_10.
Texto completo da fonteMolesini, Barbara, e Tiziana Pandolfini. "Exogenous application of RNAs as a silencing tool for discovering gene function." In RNAi for plant improvement and protection, 14–24. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789248890.0003.
Texto completo da fonteMolesini, Barbara, e Tiziana Pandolfini. "Exogenous application of RNAs as a silencing tool for discovering gene function." In RNAi for plant improvement and protection, 14–24. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789248890.0014.
Texto completo da fonteParo, Renato, Ueli Grossniklaus, Raffaella Santoro e Anton Wutz. "Biology of Chromatin". In Introduction to Epigenetics, 1–28. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-68670-3_1.
Texto completo da fonteBunnik, Evelien M., e Karine G. Le Roch. "Mechanisms Regulating Transcription inPlasmodium falciparumas Targets for Novel Antimalarial Drugs". In Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery, 421–40. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527694082.ch18.
Texto completo da fonteTrabalhos de conferências sobre o assunto "Targeted transcription regulation"
Ahmad, Salma, Hanan Nazar, Nouralhuda Alatieh, Maryam Al-Mansoob, Zainab Farooq, Muna Yusuf e Allal Ouhtit. "Validation of Novel Transcriptional Targets that Underpin CD44-promoted breast cancer cell invasion". In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0153.
Texto completo da fonteCotter, Kellie, Dimple Chakravarty, Andrea Sboner e Mark A. Rubin. "Abstract 5042: Dynamic transcriptional regulation of ERα targets in prostate cancer". In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-5042.
Texto completo da fonteYamamoto, Kaneyoshi, e Akira Ishihama. "Construction of 'Promoter Chip' for Microarray Analysis of Regulation Targets of Transcription Factors". In 2007 International Symposium on Micro-NanoMechatronics and Human Science. IEEE, 2007. http://dx.doi.org/10.1109/mhs.2007.4420839.
Texto completo da fontePark, Byeolna, Yoon Kyeong Lee e Hak Yong Kim. "Transcriptional regulation of drug target proteins from cancer related disease network". In 2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW). IEEE, 2010. http://dx.doi.org/10.1109/bibmw.2010.5703937.
Texto completo da fonteSchwentner, Raphaela, Maximilian Kauer, Sven Bilke, Gunhild Jug, Paul S. Meltzer e Heinrich Kovar. "Abstract 5341: Combinatorial regulation of E2F target genes by the oncogenic ETS transcription factor EWS-FLI1". In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-5341.
Texto completo da fonteButt, Sabrina, Timothy J. Stanek, Victoria J. Gennaro, Chris McNair, Kristen L. Pauley, Karen Knudsen e Steven B. McMahon. "Abstract LB-A29: Divergent mechanisms of transcriptional regulation by SAGA member and epigenetic modifier USP22". In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; October 26-30, 2017; Philadelphia, PA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1535-7163.targ-17-lb-a29.
Texto completo da fonteRodriguez, Esteban Jose Rodriguez, e Rodrigo Mora-Rodriguez. "miR-let-7a-2, miR103a-2 and CREB1-TF as therapeutic targets to regulate the transcription of DISC1 and PDE4D in the transcriptional regulation pathway by DISC1/ATF4 complex". In 2022 IEEE 4th International Conference on BioInspired Processing (BIP). IEEE, 2022. http://dx.doi.org/10.1109/bip56202.2022.10032479.
Texto completo da fonteRiffo, Elizabeth, Mario Palma, Catalina Alarcon, Ariel Castro, Vicente Torres e Roxana Pincheira. "Abstract C131: The SALL2 transcription factor promotes cell migration and focal adhesion turnover via regulation of integrin expression". In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-c131.
Texto completo da fonteBarbier, Roberto H., Edel M. McCrea, Jonathan D. Strope, Phoebe A. Huang, Tristan M. Sissung, Douglas K. Price, Cindy H. Chau e William D. Figg. "Abstract A069: Mechanisms governing the transcriptional regulation of the liver-specific transporter OATP1B3 in prostate cancer". In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-a069.
Texto completo da fonteGoel, Sakshi, Vipul Bhatia, Mahendra Shyamlal Palecha, Shannon Carskadon, Nallasivam Palanisamy e Bushra Ateeq. "Abstract B124: ERG mediated transcriptional regulation ofDLX1homeobox gene represents a novel mechanism underlying prostate cancer progression". In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-b124.
Texto completo da fonteRelatórios de organizações sobre o assunto "Targeted transcription regulation"
Arazi, Tzahi, Vivian Irish e Asaph Aharoni. Micro RNA Targeted Transcription Factors for Fruit Quality Improvement. United States Department of Agriculture, julho de 2008. http://dx.doi.org/10.32747/2008.7592651.bard.
Texto completo da fonteGrumet, Rebecca, Rafael Perl-Treves e Jack Staub. Ethylene Mediated Regulation of Cucumis Reproduction - from Sex Expression to Fruit Set. United States Department of Agriculture, fevereiro de 2010. http://dx.doi.org/10.32747/2010.7696533.bard.
Texto completo da fonteJander, Georg, e Daniel Chamovitz. Investigation of growth regulation by maize benzoxazinoid breakdown products. United States Department of Agriculture, janeiro de 2015. http://dx.doi.org/10.32747/2015.7600031.bard.
Texto completo da fontePichersky, Eran, Alexander Vainstein e Natalia Dudareva. Scent biosynthesis in petunia flowers under normal and adverse environmental conditions. United States Department of Agriculture, janeiro de 2014. http://dx.doi.org/10.32747/2014.7699859.bard.
Texto completo da fonteGal-On, Amit, Shou-Wei Ding, Victor P. Gaba e Harry S. Paris. role of RNA-dependent RNA polymerase 1 in plant virus defense. United States Department of Agriculture, janeiro de 2012. http://dx.doi.org/10.32747/2012.7597919.bard.
Texto completo da fonteBarg, Rivka, Erich Grotewold e Yechiam Salts. Regulation of Tomato Fruit Development by Interacting MYB Proteins. United States Department of Agriculture, janeiro de 2012. http://dx.doi.org/10.32747/2012.7592647.bard.
Texto completo da fonteWhitham, Steven A., Amit Gal-On e Victor Gaba. Post-transcriptional Regulation of Host Genes Involved with Symptom Expression in Potyviral Infections. United States Department of Agriculture, junho de 2012. http://dx.doi.org/10.32747/2012.7593391.bard.
Texto completo da fonteFromm, Hillel, Paul Michael Hasegawa e Aaron Fait. Calcium-regulated Transcription Factors Mediating Carbon Metabolism in Response to Drought. United States Department of Agriculture, junho de 2013. http://dx.doi.org/10.32747/2013.7699847.bard.
Texto completo da fonteEshed-Williams, Leor, e Daniel Zilberman. Genetic and cellular networks regulating cell fate at the shoot apical meristem. United States Department of Agriculture, janeiro de 2014. http://dx.doi.org/10.32747/2014.7699862.bard.
Texto completo da fonteOhad, Nir, e Robert Fischer. Regulation of Fertilization-Independent Endosperm Development by Polycomb Proteins. United States Department of Agriculture, janeiro de 2004. http://dx.doi.org/10.32747/2004.7695869.bard.
Texto completo da fonte