Artigos de revistas: "Science biological sciences biology molecular biology"

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Jones, Gareth. "Reformulating biological science molecular cell biology". Trends in Biochemical Sciences 12 (janeiro de 1987): 35–36. http://dx.doi.org/10.1016/0968-0004(87)90017-x.

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Thakur, Narsinh L., Roopesh Jain, Filipe Natalio, Bojan Hamer, Archana N. Thakur e Werner E. G. Müller. "Marine molecular biology: An emerging field of biological sciences". Biotechnology Advances 26, n.º 3 (maio de 2008): 233–45. http://dx.doi.org/10.1016/j.biotechadv.2008.01.001.

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de Jong, A., K. A. Kroon e A. J. M. Loonen. "Molecular Biology and Neuropsychiatry". Acta Neuropsychiatrica 6, n.º 1 (março de 1994): 12–20. http://dx.doi.org/10.1017/s0924270800033743.

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SummaryAn overview is given of some developments in the field of the molecular biological sciences with their impact on neuropsychiatry and psychopharmacology. Interference with the functioning of the cell will give some clues for the development of new psychotropic drugs. The genesis of disorders will be elucidated. This can lead to new methods of therapy. Moreover, the possibility to affect gene expression may offer opportunities for the development of new drugs. The existence and functioning of priones is explained. Interfering with neuroplastic principles may become an important method for the treatment of neurodegenerative diseases.

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D’Souza, Leo. "Jesuit Contributions to Biological Sciences in India". Journal of Jesuit Studies 7, n.º 2 (29 de janeiro de 2020): 263–81. http://dx.doi.org/10.1163/22141332-00702007.

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Jesuits in India have made significant contribution to studies in classical as well as modern biology. The earlier classical studies resulted in the compilation of well-known and highly appreciated floras. In recent times, Jesuits have kept pace with the current trends in biology and have made contributions in the areas of environmental awareness, biodiversity, conservation, biotechnology, molecular biology, bioremediation, and bioenergy as well as biopesticides.

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Zehr, J. P., I. Hewson e P. H. Moisander. "Molecular biology techniques and applications for ocean sensing". Ocean Science Discussions 5, n.º 4 (27 de novembro de 2008): 625–57. http://dx.doi.org/10.5194/osd-5-625-2008.

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Abstract. The study of marine microorganisms using molecular biological techniques is now widespread in the ocean sciences. These techniques target nucleic acids which record the evolutionary history of microbes, and encode for processes which are active in the ocean today. Here we review some of the most commonly used molecular biological techniques. Molecular biological techniques permit study of the abundance, distribution, diversity, and physiology of microorganisms in situ. These techniques include the polymerase chain reaction (PCR) and reverse-transcriptase PCR, quantitative PCR, whole assemblage "fingerprinting" approaches (based on nucleic acid sequence or length heterogeneity), oligonucleotide microarrays, and high-throughput shotgun sequencing of whole genomes and gene transcripts, which can be used to answer biological, ecological, evolutionary and biogeochemical questions in the ocean sciences. Moreover, molecular biological approaches may be deployed on ocean sensor platforms and hold promise for tracking of organisms or processes of interest in near-real time.

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Zehr, J. P., I. Hewson e P. Moisander. "Molecular biology techniques and applications for ocean sensing". Ocean Science 5, n.º 2 (8 de maio de 2009): 101–13. http://dx.doi.org/10.5194/os-5-101-2009.

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Abstract. The study of marine microorganisms using molecular biological techniques is now widespread in the ocean sciences. These techniques target nucleic acids which record the evolutionary history of microbes, and encode for processes which are active in the ocean today. Molecular techniques can form the basis of remote instrumentation sensing technologies for marine microbial diversity and ecological function. Here we review some of the most commonly used molecular biological techniques. These techniques include the polymerase chain reaction (PCR) and reverse-transcriptase PCR, quantitative PCR, whole assemblage "fingerprinting" approaches (based on nucleic acid sequence or length heterogeneity), oligonucleotide microarrays, and high-throughput shotgun sequencing of whole genomes and gene transcripts, which can be used to answer biological, ecological, evolutionary and biogeochemical questions in the ocean sciences. Moreover, molecular biological approaches may be deployed on ocean sensor platforms and hold promise for tracking of organisms or processes of interest in near-real time.

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Szathmary, E. "MOLECULAR BIOLOGY AND EVOLUTION: Can Genes Explain Biological Complexity?" Science 292, n.º 5520 (18 de maio de 2001): 1315–16. http://dx.doi.org/10.1126/science.1060852.

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Garvin-Doxas, Kathy, Michael Klymkowsky e Susan Elrod. "Building, Using, and Maximizing the Impact of Concept Inventories in the Biological Sciences: Report on a National Science Foundation–sponsored Conference on the Construction of Concept Inventories in the Biological Sciences". CBE—Life Sciences Education 6, n.º 4 (dezembro de 2007): 277–82. http://dx.doi.org/10.1187/cbe.07-05-0031.

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The meeting “Conceptual Assessment in the Biological Sciences” was held March 3–4, 2007, in Boulder, Colorado. Sponsored by the National Science Foundation and hosted by University of Colorado, Boulder's Biology Concept Inventory Team, the meeting drew together 21 participants from 13 institutions, all of whom had received National Science Foundation funding for biology education. Topics of interest included Introductory Biology, Genetics, Evolution, Ecology, and the Nature of Science. The goal of the meeting was to organize and leverage current efforts to develop concept inventories for each of these topics. These diagnostic tools are inspired by the success of the Force Concept Inventory, developed by the community of physics educators to identify student misconceptions about Newtonian mechanics. By working together, participants hope to lessen the risk that groups might develop competing rather than complementary inventories.

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DeNies, Maxwell S., Allen P. Liu e Santiago Schnell. "Are the biomedical sciences ready for synthetic biology?" Biomolecular Concepts 11, n.º 1 (24 de janeiro de 2020): 23–31. http://dx.doi.org/10.1515/bmc-2020-0003.

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AbstractThe ability to construct a functional system from its individual components is foundational to understanding how it works. Synthetic biology is a broad field that draws from principles of engineering and computer science to create new biological systems or parts with novel function. While this has drawn well-deserved acclaim within the biotechnology community, application of synthetic biology methodologies to study biological systems has potential to fundamentally change how biomedical research is conducted by providing researchers with improved experimental control. While the concepts behind synthetic biology are not new, we present evidence supporting why the current research environment is conducive for integration of synthetic biology approaches within biomedical research. In this perspective we explore the idea of synthetic biology as a discovery science research tool and provide examples of both top-down and bottom-up approaches that have already been used to answer important physiology questions at both the organismal and molecular level.

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Eldəniz qızı Əhmədova, Gülnarə. "Inclusion of bioinformatics in biological sciences". NATURE AND SCIENCE 22, n.º 7 (17 de julho de 2022): 82–86. http://dx.doi.org/10.36719/2707-1146/22/82-86.

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Bioinformatika hesablama və biologiya elmlərinin birləşməsi kimi müəyyən edilə bilər. Proteomika və genomika tədqiqatları nəticəsində yaranan məlumatların daşqını emal etmək və təhlil etmək üçün aktuallıq bioinformatikanın önəm və əhəmiyyət qazanmasına səbəb oldu. Bununla belə, onun multidissiplinar təbiəti həm biologiya, həm də hesablama sahəsində hazırlanmış mütəxəssisə unikal tələbat yaratmışdır. İcmalda bioinformatika sahəsini təşkil edən komponentlər və bioinformatika təhsili olan fərdlərin yetişdirilməsi üçün tələb olunan fərqli təhsil meyarları təsvir edilib. Məqalə həm də Malayziyada bioinformatikaya giriş və onun haqqında ümumi məlumat verəcəkdir. Malayziyada mövcud bioinformatika ssenarisi onun inkişafını ölçmək və gələcək bioinformatika təhsili strategiyalarını planlaşdırmaq üçün araşdırıldı. Müqayisə üçün biz digər ölkələrin təhsildə istifadə etdiyi metod və strategiyaları araşdırdıq ki, bioinformatikanın tətbiqini daha da təkmilləşdirmək üçün dərslər alınsın. Hesab olunur ki, akademiyadan, sənayedən dəqiq və kifayət qədər idarəetmə gələcəkdə keyfiyyətli bioinformatiklər yetişdirməyə imkan verəcək. Açar sözlər: bioinformatika, hesablama biologiyası, təhsil, biologiya elmi, bioinformatikanın tədrisi Gulnara Eldeniz Ahmadova Inclusion of bioinformatics in biological sciences Abstract Bioinformatics can be defined as the combination of computational and biological sciences. The urgency to process and analyze the flood of data resulting from proteomics and genomics research has led bioinformatics to gain prominence and importance. However, its multidisciplinary nature has created a unique need for a specialist trained in both biology and computing. In this review, we have described the components that make up the field of bioinformatics and the different educational criteria required to produce individuals with bioinformatics training. This article will also provide an introduction and overview of bioinformatics in Malaysia. The current bioinformatics scenario in Malaysia was examined to gauge its development and plan future bioinformatics education strategies. For comparison, we examined the methods and strategies used in education by other countries, so that lessons can be learned to further improve the application of bioinformatics. It is believed that accurate and sufficient management from academia and industry will enable to produce quality bioinformaticians in the future. Keywords: bioinformatics, computational biology, education, biological science, teaching bioinformatics

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Chambers, Paul. "From omics to systems biology: towards a more complete description and understanding of biology". Microbiology Australia 32, n.º 4 (2011): 141. http://dx.doi.org/10.1071/ma11141.

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Technology sets limits on what can be achieved in research. The advent of genetic engineering accompanied by the development of monoclonal antibody technology in the 1970s heralded the birth of modern ?molecular biology?. This revolutionised the way we approach research in the biological sciences by allowing access to cellular structures and processes that were in the realm of science fiction a decade earlier. The invention of the PCR in the 1980s built on this, making cloning easier and a great deal more rapid; with PCR we no longer required a host and vector to amplify DNA and isolate targeted DNA sequences.

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Reuter, Jewel. "Molecular Biology". American Biology Teacher 68, n.º 9 (1 de novembro de 2006): 567–68. http://dx.doi.org/10.2307/4452065.

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Kordyum, E. L. "SPACE BIOLOGY PROJECTS IN UKRAINE: NOWADAYS TRENDS". Kosmìčna nauka ì tehnologìâ 29, n.º 1 (14 de março de 2023): 36–51. http://dx.doi.org/10.15407/knit2023.01.036.

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We present a brief overview of the results of the implementation of biological projects conducted in frame of theTarget program of the National Academy of Sciences of Ukraine for scientific space research (2018—2022) and their contribution to the current fields of world space biology: astrobiology, cellular and molecular biology, plant biology, animal biology, and gravitational biology.

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Tranel, Patrick J., e David P. Horvath. "Molecular Biology and Genomics: New Tools for Weed Science". BioScience 59, n.º 3 (março de 2009): 207–15. http://dx.doi.org/10.1525/bio.2009.59.3.5.

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Founds, Sandra A. "Introducing Systems Biology for Nursing Science". Biological Research For Nursing 11, n.º 1 (15 de fevereiro de 2009): 73–80. http://dx.doi.org/10.1177/1099800409331893.

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Systems biology expands on general systems theory as the ``omics'' era rapidly progresses. Although systems biology has been institutionalized as an interdisciplinary framework in the biosciences, it is not yet apparent in nursing. This article introduces systems biology for nursing science by presenting an overview of the theory. This framework for the study of organisms from molecular to environmental levels includes iterations of computational modeling, experimentation, and theory building. Synthesis of complex biological processes as whole systems rather than isolated parts is emphasized. Pros and cons of systems biology are discussed, and relevance of systems biology to nursing is described. Nursing research involving molecular, physiological, or biobehavioral questions may be guided by and contribute to the developing science of systems biology. Nurse scientists can proactively incorporate systems biology into their investigations as a framework for advancing the interdisciplinary science of human health care. Systems biology has the potential to advance the research and practice goals of the National Institute for Nursing Research in the National Institutes of Health Roadmap initiative.

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Williams, R. J. P. "Molecular and thermodynamic bioenergetics". Biochemical Society Transactions 33, n.º 4 (1 de agosto de 2005): 825–28. http://dx.doi.org/10.1042/bst0330825.

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Studies of biological sciences can be approached in two ways: reductively, as in molecular biology, or holistically, as in systems biology. In this paper, I illustrate my views on approaches to bioenergetics through the analysis of molecular energy transduction and of general thermodynamics relationships in systems biology. The future lies with the second as the first is nearing completion.

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Nikam, Priya V., Sanjay Kumar, Sachinkumar D. Gunjal, Mrunalini H. Kulkarni e Surya P. Singh. "Unlocking the Potential of In-silico Approaches: Drug Development and Vaccine Design". INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 13, n.º 04 (25 de dezembro de 2023): 1606–10. http://dx.doi.org/10.25258/ijddt.13.4.74.

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Unmatched in its field, bioinformatics combines several academic fields such as statistics, computer science, mathematics, and biology to create state-of-the-art techniques for biological data retrieval, storage, and analysis that lead to a thorough understanding of the biological world. Countless options currently accessible in field of living sciences by the expansion of in-silico biology. Paradigm of life sciences has changed as a result of in-silico technologies, which offer researchers a valuable and affordable way to focus on in-silico techniques like homology modeling, epitope prediction, and molecular docking, which have impacted drug discovery and vaccine design. These techniques also provide previously unheard-of predictions and insights.

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Milam, Erika Lorraine. "The Equally Wonderful Field: Ernst Mayr and Organismic Biology". Historical Studies in the Natural Sciences 40, n.º 3 (2010): 279–317. http://dx.doi.org/10.1525/hsns.2010.40.3.279.

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Biologists in the 1960s witnessed a period of intense intra-disciplinary negotiations, especially the positioning of organismic biologists relative to molecular biologists. The perceived valorization of the physical sciences by "molecular" biologists became a catalyst creating a unified front of "organismic" biology that incorporated not just evolutionary biologists, but also students of animal behavior, ecology, systematics, botany——in short, almost any biological community that predominantly conducted their research in the field or museum and whose practitioners felt the pinch of the prestige and funding accruing to molecular biologists and biochemists. Ernst Mayr, Theodosius Dobzhansky, and George Gaylord Simpson took leading roles in defending alternatives to what they categorized as the mechanistic approach of chemistry and physics applied to living systems——the "equally wonderful field of organismic biology." Thus, it was through increasingly tense relations with molecular biology that organismic biologists cohered into a distinct community, with their own philosophical grounding, institutional security, and historical identity. Because this identity was based in large part on a fundamental rejection of the physical sciences as a desirable model within biology, organismic biologists succeeded in protecting the future of their field by emphasizing the deep divisions that ran through the biological sciences as a whole.

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Hricovíni, Miloš, Raymond J. Owens, Andrzej Bak, Violetta Kozik, Witold Musiał, Roberta Pierattelli, Magdaléna Májeková et al. "Chemistry towards Biology—Instruct: Snapshot". International Journal of Molecular Sciences 23, n.º 23 (26 de novembro de 2022): 14815. http://dx.doi.org/10.3390/ijms232314815.

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The knowledge of interactions between different molecules is undoubtedly the driving force of all contemporary biomedical and biological sciences. Chemical biology/biological chemistry has become an important multidisciplinary bridge connecting the perspectives of chemistry and biology to the study of small molecules/peptidomimetics and their interactions in biological systems. Advances in structural biology research, in particular linking atomic structure to molecular properties and cellular context, are essential for the sophisticated design of new medicines that exhibit a high degree of druggability and very importantly, druglikeness. The authors of this contribution are outstanding scientists in the field who provided a brief overview of their work, which is arranged from in silico investigation through the characterization of interactions of compounds with biomolecules to bioactive materials.

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Kostić, Daniel, Claus C. Hilgetag e Marc Tittgemeyer. "Unifying the essential concepts of biological networks: biological insights and philosophical foundations". Philosophical Transactions of the Royal Society B: Biological Sciences 375, n.º 1796 (24 de fevereiro de 2020): 20190314. http://dx.doi.org/10.1098/rstb.2019.0314.

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Over the last decades, network-based approaches have become highly popular in diverse fields of biology, including neuroscience, ecology, molecular biology and genetics. While these approaches continue to grow very rapidly, some of their conceptual and methodological aspects still require a programmatic foundation. This challenge particularly concerns the question of whether a generalized account of explanatory, organizational and descriptive levels of networks can be applied universally across biological sciences. To this end, this highly interdisciplinary theme issue focuses on the definition, motivation and application of key concepts in biological network science, such as explanatory power of distinctively network explanations, network levels and network hierarchies. This article is part of the theme issue ‘Unifying the essential concepts of biological networks: biological insights and philosophical foundations’.

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Robinson, Douglas N., e Pablo A. Iglesias. "Bringing the physical sciences into your cell biology research". Molecular Biology of the Cell 23, n.º 21 (novembro de 2012): 4167–70. http://dx.doi.org/10.1091/mbc.e12-05-0354.

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Historically, much of biology was studied by physicists and mathematicians. With the advent of modern molecular biology, a wave of researchers became trained in a new scientific discipline filled with the language of genes, mutants, and the central dogma. These new molecular approaches have provided volumes of information on biomolecules and molecular pathways from the cellular to the organismal level. The challenge now is to determine how this seemingly endless list of components works together to promote the healthy function of complex living systems. This effort requires an interdisciplinary approach by investigators from both the biological and the physical sciences.

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Usher, David C., Tobin A. Driscoll, Prasad Dhurjati, John A. Pelesko, Louis F. Rossi, Gilberto Schleiniger, Kathleen Pusecker e Harold B. White. "A Transformative Model for Undergraduate Quantitative Biology Education". CBE—Life Sciences Education 9, n.º 3 (setembro de 2010): 181–88. http://dx.doi.org/10.1187/cbe.10-03-0029.

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The BIO2010 report recommended that students in the life sciences receive a more rigorous education in mathematics and physical sciences. The University of Delaware approached this problem by (1) developing a bio-calculus section of a standard calculus course, (2) embedding quantitative activities into existing biology courses, and (3) creating a new interdisciplinary major, quantitative biology, designed for students interested in solving complex biological problems using advanced mathematical approaches. To develop the bio-calculus sections, the Department of Mathematical Sciences revised its three-semester calculus sequence to include differential equations in the first semester and, rather than using examples traditionally drawn from application domains that are most relevant to engineers, drew models and examples heavily from the life sciences. The curriculum of the B.S. degree in Quantitative Biology was designed to provide students with a solid foundation in biology, chemistry, and mathematics, with an emphasis on preparation for research careers in life sciences. Students in the program take core courses from biology, chemistry, and physics, though mathematics, as the cornerstone of all quantitative sciences, is given particular prominence. Seminars and a capstone course stress how the interplay of mathematics and biology can be used to explain complex biological systems. To initiate these academic changes required the identification of barriers and the implementation of solutions.

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Bebek, G., M. Koyuturk, N. D. Price e M. R. Chance. "Network biology methods integrating biological data for translational science". Briefings in Bioinformatics 13, n.º 4 (5 de março de 2012): 446–59. http://dx.doi.org/10.1093/bib/bbr075.

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Kunakh, V. A. "Initiation, development and achievements of molecular-biological and molecular-genetic research in Ukraine (on the 50th anniversary of the Institute of Molecular Biology and Genetics of the NAS of Ukraine)". Faktori eksperimental'noi evolucii organizmiv 32 (1 de setembro de 2023): 7–12. http://dx.doi.org/10.7124/feeo.v32.1527.

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The paper is focused on the main events that initiated molecular biological and molecular genetic research in Ukraine. It examines the main directions and achievements of these sciences in the Sector of Molecular Biology and Genetics of the D. K. Zabolotny Institute of Microbiology and Virology of the Academy of Sciences of the Ukrainian SSR that was the forerunner of the IMBG. The scientific and organizational activities of the IMBG and the contribution of its employees to the development of modern biology are briefly analyzed over the 50 years of the institute’s existence.

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Kim, Jinhee, e Jeongsik Kim. "Development of a Molecular Biology Experimental Program for Gifted Science Students to Understand Biological Characteristics through Protein Profiles". Korean Science Education Society for the Gifted 15, n.º 3 (31 de dezembro de 2023): 389–403. http://dx.doi.org/10.29306/jseg.2023.15.3.389.

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Proteins are essential biomolecules that govern cellular activities and play a crucial role in understanding the characteristics of living organisms. A proper understanding of proteins is essential for comprehending the life sciences at the molecular level. In this study, our objective is to provide an experimental educational program for science-gifted middle school students to grasp the concepts of protein-based molecular biology. The experiments we have designed aim to analyze proteins from various organisms, helping students gain insights into their characteristics. To achieve this, we extract proteins from Escherichia coli, yeast, and human plasma/blood cells, and then separate total proteins by size using protein electrophoresis after adjusting their concentrations. Subsequently, we qualitatively determine the quantity and size of proteins through protein staining/de-staining processes. This is followed by discussions and comprehension of the major proteins in relation to biological characteristics. The entire experiment takes approximately 6 hours, allowing participants to learn diverse and universally applicable molecular experimental techniques related to protein analysis. To assess the effectiveness of this program, we conducted both a pre-test and post-test with nine participants who completed the experimental module, and we also gathered additional program feedback. The results of the experimental module showed high satisfaction among the participants, who did not encounter significant difficulties in understanding the experimental content. Furthermore, there was a slight increase in interest and career aspirations in molecular biology, and knowledge of intracellular protein roles and related molecular biology significantly improved. Therefore, This experimental program is expected to facilitate students in comprehending molecular biological concepts based on proteins and establishing a foundation for conducting molecular biology-related research, and ultimately to assist in making their informed career choices in the life sciences.

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DEFORZH, Hanna. "THE THEORY OF EVOLUTIONARY DOCTRINE AND ITS ROLE IN THE FORMATION OF THE SCIENTIFIC OUTLOOK OF STUDENTS IN THE TRAINING SYSTEM FOR TEACHERS OF NATURAL EDUCATION". Scientific Bulletin of Flight Academy. Section: Pedagogical Sciences 13 (2023): 26–33. http://dx.doi.org/10.33251/2522-1477-2023-13-26-33.

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The article examines the importance of the educational discipline ″Theory of Evolutionary Teaching″ in the system of training future teachers of natural sciences. The role of this discipline in the formation of students’ scientific outlook is highlighted. The main part of the scientific worldview contains the views and beliefs that were formed on the basis of knowledge about nature and society and became the internal position of the individual. The theory of evolution forms scientific views and beliefs about the structure of the universe, the origin of life on Earth, the origin of man, and others. The educational and professional programs implemented in the Volodymyr Vynnychenko Central Ukrainian State University at the Department of Natural Sciences and Methods of their teaching were analyzed. These educational and professional programs present a number of general, professional competencies and program learning outcomes. Among general competencies, the ability to form a scientific worldview, development of human existence, society and nature, and spiritual culture are listed. Among the professional competences, the ability to use biological concepts, laws, concepts, teachings and theories of Biology to explain and develop students' understanding of the integrity and interdependence of living systems and organisms are mentioned; the ability to understand and be able to explain the structure, functions, vital activity, reproduction, classification, origin, distribution, use of living organisms and systems of all levels of organization; the ability to reveal the essence of biological phenomena, processes and technologies, to solve biological problems; the ability to explain to specialists and non-specialists the strategy of sustainable development of mankind and ways of solving its global problems based on a deep understanding of modern problems of natural sciences. Among the learning outcomes, it is indicated that a student knows biological terminology and nomenclature, understands the basic concepts, theories and general structure of biological science; as well he or she knows the basic laws and provisions of genetics, molecular biology, and the theory of evolution. The working program of the academic discipline and its contents were also analyzed. The structure and integration of this subject is shown, which combines such natural sciences as: genetics, molecular biology, biochemistry, ecology, paleontology, morphology, systematics, embryology, comparative anatomy and physiology, anthropology, biophysics, quantum physics, nuclear physics, astronomy, biocybernetics, biogeography, paleogeography, geology and other sciences. Keywords: theory of evolutionary teaching, natural sciences, biology, biology and chemistry teacher, natural sciences teacher, scientific outlook, competences.

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Bloom, Mark. "Molecular Biology & Technology: Helping Students Understand the Nature of Science". American Biology Teacher 63, n.º 8 (1 de outubro de 2001): 557–60. http://dx.doi.org/10.2307/4451187.

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Bloom, Mark. "Molecular Biology & Technology Helping Students Understand the Nature of Science". American Biology Teacher 63, n.º 8 (outubro de 2001): 557–60. http://dx.doi.org/10.1662/0002-7685(2001)063[0557:mbthsu]2.0.co;2.

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Stevens, Charles F. "Systems biology versus molecular biology". Current Biology 14, n.º 2 (janeiro de 2004): R51—R52. http://dx.doi.org/10.1016/j.cub.2003.12.040.

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Santarelli, Michelle. "Cellular and Molecular Biology". American Biology Teacher 65, n.º 2 (1 de fevereiro de 2003): 148–50. http://dx.doi.org/10.2307/4451456.

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Belén Paredes, Maria, e Maria Eugenia Sulen. "An overview of synthetic biology". Bionatura 5, n.º 1 (15 de fevereiro de 2020): 1088–92. http://dx.doi.org/10.21931/rb/2020.05.01.14.

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Synthetic Biology is the combination of basic sciences with engineering. The aim of Synthetic Biology is to create, design, and redesign biological systems and devices to understand biological processes and to achieve useful and sophisticated functionalities to improve human welfare. When the engineering community took part in the discussion for the definition of Synthetic Biology, the idea of extraction and reassembly of “biological parts” along with the principles of abstraction, modularity, and standardization was introduced. Genetic Engineering is one of the many essential tools for synthetic biology, and even though they share the DNA manipulation basis and approach to intervene in the complexity of molecular biology, they differ in many aspects, and the two terms should not be used interchangeably. Some of the applications that have already been done by Synthetic Biology include the production of 1,4-butanediol (BDO), the antimalarial drug artemisinin, and the anticancer compound taxol. The potential of Synthetic Biology to design new genomes without immediate biological ancestry has raised ontological, political, economic, and ethical concerns based on the possibility that synthetic biology may be intrinsically unethical.

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Thompson, Katerina V., Jean Chmielewski, Michael S. Gaines, Christine A. Hrycyna e William R. LaCourse. "Competency-Based Reforms of the Undergraduate Biology Curriculum: Integrating the Physical and Biological Sciences". CBE—Life Sciences Education 12, n.º 2 (junho de 2013): 162–69. http://dx.doi.org/10.1187/cbe.12-09-0143.

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The National Experiment in Undergraduate Science Education project funded by the Howard Hughes Medical Institute is a direct response to the Scientific Foundations for Future Physicians report, which urged a shift in premedical student preparation from a narrow list of specific course work to a more flexible curriculum that helps students develop broad scientific competencies. A consortium of four universities is working to create, pilot, and assess modular, competency-based curricular units that require students to use higher-order cognitive skills and reason across traditional disciplinary boundaries. Purdue University; the University of Maryland, Baltimore County; and the University of Miami are each developing modules and case studies that integrate the biological, chemical, physical, and mathematical sciences. The University of Maryland, College Park, is leading the effort to create an introductory physics for life sciences course that is reformed in both content and pedagogy. This course has prerequisites of biology, chemistry, and calculus, allowing students to apply strategies from the physical sciences to solving authentic biological problems. A comprehensive assessment plan is examining students’ conceptual knowledge of physics, their attitudes toward interdisciplinary approaches, and the development of specific scientific competencies. Teaching modules developed during this initial phase will be tested on multiple partner campuses in preparation for eventual broad dissemination.

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Cowden, Ronald R., E. D. P. DeRobertis e E. M. F. DeRobertis. "Cell and Molecular Biology". Transactions of the American Microscopical Society 107, n.º 1 (janeiro de 1988): 16. http://dx.doi.org/10.2307/3226401.

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Strasser, Bruno J., Michel Morange e Matthew Cobb. "Molecular Biology, Macroscopic History". BioScience 49, n.º 11 (novembro de 1999): 929. http://dx.doi.org/10.2307/1313654.

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Hiscott, Laura. "Physics for biological breakthroughs". Physics World 34, n.º 9 (1 de dezembro de 2021): 49–50. http://dx.doi.org/10.1088/2058-7058/34/09/34.

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It might not sound like an obvious place for a physicist to work, but the European Molecular Biology Laboratory (EMBL) is highly multidisciplinary, employing people from across all scientific fields. Laura Hiscott speaks to Wolfgang Huber, a physicist at EMBL who uses his mathematical skills to contribute to the life sciences.

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Metz, Anneke M. "Teaching Statistics in Biology: Using Inquiry-based Learning to Strengthen Understanding of Statistical Analysis in Biology Laboratory Courses". CBE—Life Sciences Education 7, n.º 3 (setembro de 2008): 317–26. http://dx.doi.org/10.1187/cbe.07-07-0046.

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There is an increasing need for students in the biological sciences to build a strong foundation in quantitative approaches to data analyses. Although most science, engineering, and math field majors are required to take at least one statistics course, statistical analysis is poorly integrated into undergraduate biology course work, particularly at the lower-division level. Elements of statistics were incorporated into an introductory biology course, including a review of statistics concepts and opportunity for students to perform statistical analysis in a biological context. Learning gains were measured with an 11-item statistics learning survey instrument developed for the course. Students showed a statistically significant 25% (p < 0.005) increase in statistics knowledge after completing introductory biology. Students improved their scores on the survey after completing introductory biology, even if they had previously completed an introductory statistics course (9%, improvement p < 0.005). Students retested 1 yr after completing introductory biology showed no loss of their statistics knowledge as measured by this instrument, suggesting that the use of statistics in biology course work may aid long-term retention of statistics knowledge. No statistically significant differences in learning were detected between male and female students in the study.

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Śmigiel, Wojciech Mikołaj, Pauline Lefrançois e Bert Poolman. "Physicochemical considerations for bottom-up synthetic biology". Emerging Topics in Life Sciences 3, n.º 5 (28 de agosto de 2019): 445–58. http://dx.doi.org/10.1042/etls20190017.

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The bottom-up construction of synthetic cells from molecular components is arguably one of the most challenging areas of research in the life sciences. We review the impact of confining biological systems in synthetic vesicles. Complex cell-like systems require control of the internal pH, ionic strength, (macro)molecular crowding, redox state and metabolic energy conservation. These physicochemical parameters influence protein activity and need to be maintained within limits to ensure the system remains in steady-state. We present the physicochemical considerations for building synthetic cells with dimensions ranging from the smallest prokaryotes to eukaryotic cells.

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Sheppard, Keith, e Dennis M. Robbins. "High School Biology Today: What the Committee of Ten Actually Said". CBE—Life Sciences Education 6, n.º 3 (setembro de 2007): 198–202. http://dx.doi.org/10.1187/cbe.07-03-0013.

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This essay describes how in the 1890s the Committee of Ten arrived at their recommendations about the organization of the high school biological sciences and seeks to correct the frequently held, but erroneous view that the Committee of Ten was the initiator of the Biology-Chemistry-Physics order of teaching sciences prevalent in high schools today. The essay details the factors underlying the changing views of high school biology from its “natural history” origins, through its “zoology, botany, physiology” disciplinary phase to its eventual integration into a “general biology” course. The simultaneous parallel development of the “Carnegie Unit” for measuring coursework is highlighted as a significant contributor in the evolution of the present day high school biology course. The essay concludes with a discussion of the implications of the grade placement of the sciences for the future development of high school biology.

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VETTEL, ERIC J. "The protean nature of Stanford University's biological sciences, 1946––1972". Historical Studies in the Physical and Biological Sciences 35, n.º 1 (1 de setembro de 2004): 95–113. http://dx.doi.org/10.1525/hsps.2004.35.1.95.

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ABSTRACT: Academic literature has paid scant attention to the biological sciences at Stanford University, an omission all the more conspicuous considering their productivity since World War II. This article draws on previously unused archival material to establish a starting point for further study of the biological sciences at Stanford. It traces the evolution of Stanford's biological sciences through three experimental fields: self-directed developmental and evolutionary studies; fundamental research at the molecular level; and biomedical applications of fundamental knowledge. Taken together, a history of Stanford's biological sciences offers a remarkably fertile example of organizational flexibility in historical context. This essay ends by suggesting that a fourth phase of biological research at Stanford will be governed by commercial interest in biology.

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Radick, Gregory. "Other Histories, Other Biologies". Royal Institute of Philosophy Supplement 56 (março de 2005): 21–47. http://dx.doi.org/10.1017/s1358246100008778.

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When philosophers look to the history of biology, they most often ask about what happened, and how best to describe it. They ask, for instance, whether molecular genetics subsumed the Mendelian genetics preceding it, or whether these two sciences have maintained rather messier relations. Here I wish to pose a question as much about what did not happen as what did. My concern is with the strength of the links between our biological science—our biology—and the particular history which brought that science into being. Would quite different histories have produced roughly the same science? Or, on the contrary, would different histories have produced other, quite different biologies?

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Radick, Gregory. "Other Histories, Other Biologies". Royal Institute of Philosophy Supplement 56 (dezembro de 2005): 3–4. http://dx.doi.org/10.1017/s135824610505602x.

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When philosophers look to the history of biology, they most often ask about what happened, and how best to describe it. They ask, for instance, whether molecular genetics subsumed the Mendelian genetics preceding it, or whether these two sciences have main–tained rather messier relations. Here I wish to pose a question as much about what did not happen as what did. My concern is with the strength of the links between our biological science—our biology—and the particular history which brought that science into being. Would quite different histories have produced roughly the same science? Or, on the contrary, would different histories have produced other, quite different biologies?

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Waite, J. Herbert. "Translational bioadhesion research: embracing biology without tokenism". Philosophical Transactions of the Royal Society B: Biological Sciences 374, n.º 1784 (9 de setembro de 2019): 20190207. http://dx.doi.org/10.1098/rstb.2019.0207.

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Bioadhesion has attracted a sizable research community of scientists and engineers that is striving increasingly for translational outcomes in anti-fouling and bioinspired adhesion initiatives. As bioadhesion is highly context-dependent, attempts to trivialize or gloss over the fundamental physical, chemical and biological sciences involved will compromise the relevance and durability of translation. This article is part of the theme issue ‘Transdisciplinary approaches to the study of adhesion and adhesives in biological systems'.

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Fogg, Christiana N. "ISMB 2016 offers outstanding science, networking, and celebration". F1000Research 5 (14 de junho de 2016): 1371. http://dx.doi.org/10.12688/f1000research.8640.1.

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The annual international conference on Intelligent Systems for Molecular Biology (ISMB) is the major meeting of the International Society for Computational Biology (ISCB). Over the past 23 years the ISMB conference has grown to become the world's largest bioinformatics/computational biology conference. ISMB 2016 will be the year's most important computational biology event globally. The conferences provide a multidisciplinary forum for disseminating the latest developments in bioinformatics/computational biology. ISMB brings together scientists from computer science, molecular biology, mathematics, statistics and related fields. Its principal focus is on the development and application of advanced computational methods for biological problems. ISMB 2016 offers the strongest scientific program and the broadest scope of any international bioinformatics/computational biology conference. Building on past successes, the conference is designed to cater to variety of disciplines within the bioinformatics/computational biology community. ISMB 2016 takes place July 8 - 12 at the Swan and Dolphin Hotel in Orlando, Florida, United States. For two days preceding the conference, additional opportunities including Satellite Meetings, Student Council Symposium, and a selection of Special Interest Group Meetings and Applied Knowledge Exchange Sessions (AKES) are all offered to enable registered participants to learn more on the latest methods and tools within specialty research areas.

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Masomi, Hayatullah. "The Application of Mathematical Series in Sciences". Journal of Mathematics and Statistics Studies 4, n.º 4 (8 de novembro de 2023): 76–83. http://dx.doi.org/10.32996/jmss.2023.4.4.8.

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Mathematical series and sequences are crucial in scientific disciplines to identify patterns, make predictions, and deduce mathematical correlations between variables. Chemistry, biology and physics rely heavily on mathematical series to model complex systems, make precise predictions, and identify fundamental principles of chemical and biological processes. The study used a qualitative approach to identify mathematical series used in scientific research and evaluate their application in chemistry and biology. A comprehensive literature review was conducted to gather pertinent papers and articles from credible scientific databases, followed by a thematic analysis strategy to examine the content. The findings of the study revealed that mathematical series are widely used in various fields, including chemistry, biology, and physics. The Taylor series, power series expansion, Fibonacci series, power series and binomial series are some of the most commonly used series. They approximate functions, express reaction rates, solve linear equations, depict spiral patterns, study population growth, and analyze genetics and molecular biology. They are crucial tools in physics, quantum mechanics, and natural phenomena description.

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Ogren, Paul J., Michael Deibel, Ian Kelly, Amy B. Mulnix e Charlie Peck. "Web Camera Use in Developmental Biology Molecular Biology & Biochemistry Laboratories". American Biology Teacher 66, n.º 1 (1 de janeiro de 2004): 57–63. http://dx.doi.org/10.2307/4451618.

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Ogren, Paul J., Michael Deibel, Ian Kelly, Amy B. Mulnix e Charlie Peck. "Web Camera Use in Developmental Biology, Molecular Biology & Biochemistry Laboratories". American Biology Teacher 66, n.º 1 (janeiro de 2004): 57–63. http://dx.doi.org/10.1662/0002-7685(2004)066[0057:wcuidb]2.0.co;2.

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Dolinski, Kara, e Olga G. Troyanskaya. "Implications of Big Data for cell biology". Molecular Biology of the Cell 26, n.º 14 (5 de julho de 2015): 2575–78. http://dx.doi.org/10.1091/mbc.e13-12-0756.

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“Big Data” has surpassed “systems biology” and “omics” as the hottest buzzword in the biological sciences, but is there any substance behind the hype? Certainly, we have learned about various aspects of cell and molecular biology from the many individual high-throughput data sets that have been published in the past 15–20 years. These data, although useful as individual data sets, can provide much more knowledge when interrogated with Big Data approaches, such as applying integrative methods that leverage the heterogeneous data compendia in their entirety. Here we discuss the benefits and challenges of such Big Data approaches in biology and how cell and molecular biologists can best take advantage of them.

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Cohn, Jeffrey P. "The Molecular Biology of Aging". BioScience 37, n.º 2 (fevereiro de 1987): 99–102. http://dx.doi.org/10.2307/1310361.

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Sansom, Clare. "The way forward?: The growth of systems biology". Biochemist 29, n.º 5 (1 de outubro de 2007): 24–26. http://dx.doi.org/10.1042/bio02905024.

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Systems biology is certainly fashionable. In the UK, the Biotechnology and Biological Sciences Research Council has put forward the majority of an investment of well over £70 million to set up six university-based ‘centres of integrative systems biology’. Other countries are making similar investments. A few years ago, however, as with ‘bioinformatics’ a decade or so earlier, it seemed that there were almost as many definitions of systems biology as there were practitioners. It is not too much of an exaggeration to say that almost any computer analysis of a biological problem might have been badged in that way.

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Zhang, Peng, Bernd Friebe, Bikram Gill e R. F. Park. "Cytogenetics in the age of molecular genetics". Australian Journal of Agricultural Research 58, n.º 6 (2007): 498. http://dx.doi.org/10.1071/ar07054.

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From the beginning of the 20th Century, we have seen tremendous advances in knowledge and understanding in almost all biological disciplines, including genetics, molecular biology, structural and functional genomics, and biochemistry. Among these advances, cytogenetics has played an important role. This paper details some of the important milestones of modern cytogenetics. Included are the historical role of cytogenetics in genetic studies in general and the genetics stocks produced using cytogenetic techniques. The basic biological questions cytogenetics can address and the important role and practical applications of cytogenetics in applied sciences, such as in agriculture and in breeding for disease resistance in cereals, are also discussed. The goal of this paper is to show that cytogenetics remains important in the age of molecular genetics, because it is inseparable from overall genome analysis. Cytogenetics complements studies in other disciplines within the field of biology and provides the basis for linking genetics, molecular biology and genomics research.

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