Artigos de revistas sobre o tema "RNA-Targeted small molecules"
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Costales, Matthew G., Haruo Aikawa, Yue Li, Jessica L. Childs-Disney, Daniel Abegg, Dominic G. Hoch, Sai Pradeep Velagapudi et al. "Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer". Proceedings of the National Academy of Sciences 117, n.º 5 (21 de janeiro de 2020): 2406–11. http://dx.doi.org/10.1073/pnas.1914286117.
Texto completo da fonteNagano, Konami, Takashi Kamimura e Gota Kawai. "Interaction between a fluoroquinolone derivative and RNAs with a single bulge". Journal of Biochemistry 171, n.º 2 (16 de novembro de 2021): 239–44. http://dx.doi.org/10.1093/jb/mvab124.
Texto completo da fonteSun, Saisai, Jianyi Yang e Zhaolei Zhang. "RNALigands: a database and web server for RNA–ligand interactions". RNA 28, n.º 2 (3 de novembro de 2021): 115–22. http://dx.doi.org/10.1261/rna.078889.121.
Texto completo da fonteTadesse, Kisanet, e Raphael I. Benhamou. "Targeting MicroRNAs with Small Molecules". Non-Coding RNA 10, n.º 2 (14 de março de 2024): 17. http://dx.doi.org/10.3390/ncrna10020017.
Texto completo da fonteWu, Liping, Jing Pan, Vala Thoroddsen, Deborah R. Wysong, Ronald K. Blackman, Christine E. Bulawa, Alexandra E. Gould et al. "Novel Small-Molecule Inhibitors of RNA Polymerase III". Eukaryotic Cell 2, n.º 2 (abril de 2003): 256–64. http://dx.doi.org/10.1128/ec.2.2.256-264.2003.
Texto completo da fonteAngelbello, Alicia J., Suzanne G. Rzuczek, Kendra K. Mckee, Jonathan L. Chen, Hailey Olafson, Michael D. Cameron, Walter N. Moss, Eric T. Wang e Matthew D. Disney. "Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model". Proceedings of the National Academy of Sciences 116, n.º 16 (29 de março de 2019): 7799–804. http://dx.doi.org/10.1073/pnas.1901484116.
Texto completo da fonteAlagia, Adele, Jana Tereňová, Ruth F. Ketley, Arianna Di Fazio, Irina Chelysheva e Monika Gullerova. "Small vault RNA1-2 modulates expression of cell membrane proteins through nascent RNA silencing". Life Science Alliance 6, n.º 6 (10 de abril de 2023): e202302054. http://dx.doi.org/10.26508/lsa.202302054.
Texto completo da fonteFrancois-Moutal, Liberty, David Donald Scott e May Khanna. "Direct targeting of TDP-43, from small molecules to biologics: the therapeutic landscape". RSC Chemical Biology 2, n.º 4 (2021): 1158–66. http://dx.doi.org/10.1039/d1cb00110h.
Texto completo da fonteSmola, Matthew J., Krista Marran, Sarah E. Thompson, Brittani Patterson, Roheeth K. Pavana, Caleb Sutherland, Jessica A. Sorrentino e Katherine D. Warner. "Abstract 680: Leveraging an RNA-targeting platform for the discovery of cell-active c-MYC mRNA-binding small molecules". Cancer Research 84, n.º 6_Supplement (22 de março de 2024): 680. http://dx.doi.org/10.1158/1538-7445.am2024-680.
Texto completo da fonteMirón-Barroso, Sofía, Joana S. Correia, Adam E. Frampton, Mark P. Lythgoe, James Clark, Laura Tookman, Silvia Ottaviani et al. "Polymeric Carriers for Delivery of RNA Cancer Therapeutics". Non-Coding RNA 8, n.º 4 (2 de agosto de 2022): 58. http://dx.doi.org/10.3390/ncrna8040058.
Texto completo da fonteMartín-Villamil, María, Isaías Sanmartín, Ángela Moreno e José Gallego. "Pharmacophore-Based Discovery of Viral RNA Conformational Modulators". Pharmaceuticals 15, n.º 6 (14 de junho de 2022): 748. http://dx.doi.org/10.3390/ph15060748.
Texto completo da fonteHardigan, Andrew A., Brian S. Roberts, Dianna E. Moore, Ryne C. Ramaker, Angela L. Jones e Richard M. Myers. "CRISPR/Cas9-targeted removal of unwanted sequences from small-RNA sequencing libraries". Nucleic Acids Research 47, n.º 14 (5 de junho de 2019): e84-e84. http://dx.doi.org/10.1093/nar/gkz425.
Texto completo da fonteTran, Anh Thi-Phuong, Duc Huy Vo, Audrey Di Giorgio e Maria Duca. "ID: 1083 Targeting the production of oncogenic miRNAs using synthetic small molecules". Biomedical Research and Therapy 4, S (5 de setembro de 2017): 170. http://dx.doi.org/10.15419/bmrat.v4is.357.
Texto completo da fontePalazzotti, Deborah, Martina Sguilla, Giuseppe Manfroni, Violetta Cecchetti, Andrea Astolfi e Maria Letizia Barreca. "Small Molecule Drugs Targeting Viral Polymerases". Pharmaceuticals 17, n.º 5 (20 de maio de 2024): 661. http://dx.doi.org/10.3390/ph17050661.
Texto completo da fonteLiu, Yuan, Mads B. Larsen, Bo Lin, Jason R. Kennerdell, Irene Alfaras, Daniel P. Camarco, Ferhan Tuncer, Toren Finkel e Bill B. Chen. "Abstract 1805: Identification of a small molecule that induces targeted protein degradation of ADAR1". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 1805. http://dx.doi.org/10.1158/1538-7445.am2023-1805.
Texto completo da fonteAkbar, Sehrish, Yao Wei e Mu-Qing Zhang. "RNA Interference: Promising Approach to Combat Plant Viruses". International Journal of Molecular Sciences 23, n.º 10 (10 de maio de 2022): 5312. http://dx.doi.org/10.3390/ijms23105312.
Texto completo da fonteCotten, M., G. Schaffner e M. L. Birnstiel. "Ribozyme, antisense RNA, and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre-mRNA processing in vitro". Molecular and Cellular Biology 9, n.º 10 (outubro de 1989): 4479–87. http://dx.doi.org/10.1128/mcb.9.10.4479-4487.1989.
Texto completo da fonteCotten, M., G. Schaffner e M. L. Birnstiel. "Ribozyme, antisense RNA, and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre-mRNA processing in vitro." Molecular and Cellular Biology 9, n.º 10 (outubro de 1989): 4479–87. http://dx.doi.org/10.1128/mcb.9.10.4479.
Texto completo da fonteThaper, Daksh L., Ravi Munuganti, Shaghayegh Nouruzi, Sahil Kumar, Soojin Kim, Sepideh Vahid, Olena Sivak et al. "First-in-field small molecule inhibitors targeting BRN2 as a therapeutic strategy for small cell prostate cancer." Journal of Clinical Oncology 37, n.º 7_suppl (1 de março de 2019): 260. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.260.
Texto completo da fonteAla, Ugo. "Competing Endogenous RNAs, Non-Coding RNAs and Diseases: An Intertwined Story". Cells 9, n.º 7 (28 de junho de 2020): 1574. http://dx.doi.org/10.3390/cells9071574.
Texto completo da fonteRimoldi, O. J., B. Raghu, M. K. Nag e G. L. Eliceiri. "Three new small nucleolar RNAs that are psoralen cross-linked in vivo to unique regions of pre-rRNA". Molecular and Cellular Biology 13, n.º 7 (julho de 1993): 4382–90. http://dx.doi.org/10.1128/mcb.13.7.4382-4390.1993.
Texto completo da fonteRimoldi, O. J., B. Raghu, M. K. Nag e G. L. Eliceiri. "Three new small nucleolar RNAs that are psoralen cross-linked in vivo to unique regions of pre-rRNA." Molecular and Cellular Biology 13, n.º 7 (julho de 1993): 4382–90. http://dx.doi.org/10.1128/mcb.13.7.4382.
Texto completo da fonteFei, Yue, Tünde Nyikó e Attila Molnar. "Non-perfectly matching small RNAs can induce stable and heritable epigenetic modifications and can be used as molecular markers to trace the origin and fate of silencing RNAs". Nucleic Acids Research 49, n.º 4 (1 de fevereiro de 2021): 1900–1913. http://dx.doi.org/10.1093/nar/gkab023.
Texto completo da fonteTao, Wei, Arif Yurdagul, Na Kong, Wenliang Li, Xiaobo Wang, Amanda C. Doran, Chan Feng et al. "siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice". Science Translational Medicine 12, n.º 553 (22 de julho de 2020): eaay1063. http://dx.doi.org/10.1126/scitranslmed.aay1063.
Texto completo da fonteRojas-Cruz, Alexis Felipe, e Clara Isabel Bermúdez-Santana. "Computational Prediction of RNA–RNA Interactions between Small RNA Tracks from Betacoronavirus Nonstructural Protein 3 and Neurotrophin Genes during Infection of an Epithelial Lung Cancer Cell Line: Potential Role of Novel Small Regulatory RNA". Viruses 15, n.º 8 (28 de julho de 2023): 1647. http://dx.doi.org/10.3390/v15081647.
Texto completo da fonteAlonso-Valenteen, Felix, Sayuri Pacheco, Dustin Srinivas, Altan Rentsendorj, David Chu, Jay Lubow, Jessica Sims et al. "HER3-targeted protein chimera forms endosomolytic capsomeres and self-assembles into stealth nucleocapsids for systemic tumor homing of RNA interference in vivo". Nucleic Acids Research 47, n.º 21 (16 de outubro de 2019): 11020–43. http://dx.doi.org/10.1093/nar/gkz900.
Texto completo da fonteServan de Almeida, Renata, Djénéba Keita, Geneviève Libeau e Emmanuel Albina. "Control of ruminant morbillivirus replication by small interfering RNA". Journal of General Virology 88, n.º 8 (1 de agosto de 2007): 2307–11. http://dx.doi.org/10.1099/vir.0.82981-0.
Texto completo da fonteGoldberg, Zelanna, Christian Maine, Gabrielle P. Dailey, Christine Domingo, Gaelle Picarda, Hunter Little, Annie Chou et al. "Abstract 6403: A self-replicating RNA precision medicine approach to overcoming resistance to endocrine therapy in ER+BC". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 6403. http://dx.doi.org/10.1158/1538-7445.am2023-6403.
Texto completo da fonteLi, Quan, Yanan Wang, Zhihui Sun, Haiyang Li e Huan Liu. "The Biosynthesis Process of Small RNA and Its Pivotal Roles in Plant Development". International Journal of Molecular Sciences 25, n.º 14 (12 de julho de 2024): 7680. http://dx.doi.org/10.3390/ijms25147680.
Texto completo da fonteAshander, Liam M., Binoy Appukuttan, Yuefang Ma, Dione Gardner-Stephen e Justine R. Smith. "Targeting Endothelial Adhesion Molecule Transcription for Treatment of Inflammatory Disease: A Proof-of-Concept Study". Mediators of Inflammation 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/7945848.
Texto completo da fonteHassanzadeh, Leila, Suxiang Chen e Rakesh Veedu. "Radiolabeling of Nucleic Acid Aptamers for Highly Sensitive Disease-Specific Molecular Imaging". Pharmaceuticals 11, n.º 4 (15 de outubro de 2018): 106. http://dx.doi.org/10.3390/ph11040106.
Texto completo da fonteLavender, Helen, Kevin Brady, Frances Burden, Oona Delpuech-Adams, Hubert Denise, Amy Palmer, Hannah Perkins et al. "In VitroCharacterization of the Activity of PF-05095808, a Novel Biological Agent for Hepatitis C Virus Therapy". Antimicrobial Agents and Chemotherapy 56, n.º 3 (27 de dezembro de 2011): 1364–75. http://dx.doi.org/10.1128/aac.05357-11.
Texto completo da fonteColl-SanMartin, Laia, Veronica Davalos, David Piñeyro, Margalida Rosselló-Tortella, Alberto Bueno-Costa, Fernando Setien, Alberto Villanueva et al. "Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer". Cancers 13, n.º 8 (14 de abril de 2021): 1869. http://dx.doi.org/10.3390/cancers13081869.
Texto completo da fonteHagiwara, Shinji, Aaron McClelland e Phillip Kantharidis. "MicroRNA in Diabetic Nephropathy: Renin Angiotensin, AGE/RAGE, and Oxidative Stress Pathway". Journal of Diabetes Research 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/173783.
Texto completo da fonteJoshi, Mansi, Pranay Dey e Abhijit De. "Recent advancements in targeted protein knockdown technologies—emerging paradigms for targeted therapy". Exploration of Targeted Anti-tumor Therapy 4, n.º 6 (26 de dezembro de 2023): 1227–48. http://dx.doi.org/10.37349/etat.2023.00194.
Texto completo da fonteTidwell, Elizabeth D., Ingrid R. Kilde, Suada Leskaj e Markos Koutmos. "Fluorescent Ligand Equilibrium Displacement: A High-Throughput Method for Identification of FMN Riboswitch-Binding Small Molecules". International Journal of Molecular Sciences 25, n.º 2 (6 de janeiro de 2024): 735. http://dx.doi.org/10.3390/ijms25020735.
Texto completo da fonteKalynych, Sergei, Lenka Pálková e Pavel Plevka. "The Structure of Human Parechovirus 1 Reveals an Association of the RNA Genome with the Capsid". Journal of Virology 90, n.º 3 (18 de novembro de 2015): 1377–86. http://dx.doi.org/10.1128/jvi.02346-15.
Texto completo da fonteShen, Linyuan, Zhendong Tan, Mailin Gan, Qiang Li, Lei Chen, Lili Niu, Dongmei Jiang et al. "tRNA-Derived Small Non-Coding RNAs as Novel Epigenetic Molecules Regulating Adipogenesis". Biomolecules 9, n.º 7 (11 de julho de 2019): 274. http://dx.doi.org/10.3390/biom9070274.
Texto completo da fonteSimba-Lahuasi, Alvaro, Ángel Cantero-Camacho, Romel Rosales, Briana Lynn McGovern, M. Luis Rodríguez, Vicente Marchán, Kris M. White, Adolfo García-Sastre e José Gallego. "SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules". Pharmaceuticals 15, n.º 12 (22 de novembro de 2022): 1448. http://dx.doi.org/10.3390/ph15121448.
Texto completo da fonteHarrington, Lucas B., David Burstein, Janice S. Chen, David Paez-Espino, Enbo Ma, Isaac P. Witte, Joshua C. Cofsky, Nikos C. Kyrpides, Jillian F. Banfield e Jennifer A. Doudna. "Programmed DNA destruction by miniature CRISPR-Cas14 enzymes". Science 362, n.º 6416 (18 de outubro de 2018): 839–42. http://dx.doi.org/10.1126/science.aav4294.
Texto completo da fonteMourenza, Álvaro, Blanca Lorente-Torres, Elena Durante, Jesús Llano-Verdeja, Jesús F. Aparicio, Arsenio Fernández-López, José A. Gil, Luis M. Mateos e Michal Letek. "Understanding microRNAs in the Context of Infection to Find New Treatments against Human Bacterial Pathogens". Antibiotics 11, n.º 3 (8 de março de 2022): 356. http://dx.doi.org/10.3390/antibiotics11030356.
Texto completo da fonteCrisci, Amitrano, Saggese, Muto, Sarno, Mele, Vitale, Ronga, Berretta e Di Francia. "Overview of Current Targeted Anti-Cancer Drugs for Therapy in Onco-Hematology". Medicina 55, n.º 8 (28 de julho de 2019): 414. http://dx.doi.org/10.3390/medicina55080414.
Texto completo da fonteCiccone, Giuseppe, Maria Luigia Ibba, Gabriele Coppola, Silvia Catuogno e Carla Lucia Esposito. "The Small RNA Landscape in NSCLC: Current Therapeutic Applications and Progresses". International Journal of Molecular Sciences 24, n.º 7 (24 de março de 2023): 6121. http://dx.doi.org/10.3390/ijms24076121.
Texto completo da fonteMorais, Pedro, Rui Zhang e Yi-Tao Yu. "Therapeutic Nonsense Suppression Modalities: From Small Molecules to Nucleic Acid-Based Approaches". Biomedicines 12, n.º 6 (10 de junho de 2024): 1284. http://dx.doi.org/10.3390/biomedicines12061284.
Texto completo da fonteXiao, Fei, Chenglong Wang, Jianping Peng, Xing Zhou, Ding Ma, Yu Wang, Yanpeng Li, Xiaodong Chen e Chuandong Wang. "Changes in Small Noncoding RNA Expression during Chondrocyte Senescence". CARTILAGE 13, n.º 3 (julho de 2022): 194760352211181. http://dx.doi.org/10.1177/19476035221118165.
Texto completo da fonteKakumani, Pavan Kumar, Louis-Mathieu Harvey, François Houle, Tanit Guitart, Fátima Gebauer e Martin J. Simard. "CSDE1 controls gene expression through the miRNA-mediated decay machinery". Life Science Alliance 3, n.º 4 (11 de março de 2020): e201900632. http://dx.doi.org/10.26508/lsa.201900632.
Texto completo da fonteCunningham, Tyler A., Derek Essegian, Stephan Schürer e Jonathan H. Schatz. "Identification of Tractable Drug-like eIF4Al Inhibitors with Potent Anti-Tumor Activity". Blood 134, Supplement_1 (13 de novembro de 2019): 5760. http://dx.doi.org/10.1182/blood-2019-130494.
Texto completo da fonteAughton, Karen, Helen Kalirai e Sarah E. Coupland. "MicroRNAs and Uveal Melanoma: Understanding the Diverse Role of These Small Molecular Regulators". International Journal of Molecular Sciences 21, n.º 16 (6 de agosto de 2020): 5648. http://dx.doi.org/10.3390/ijms21165648.
Texto completo da fonteChauhan, Waseem, Sudharshan SJ, Sweta Kafle e Rahima Zennadi. "SnoRNAs: Exploring Their Implication in Human Diseases". International Journal of Molecular Sciences 25, n.º 13 (29 de junho de 2024): 7202. http://dx.doi.org/10.3390/ijms25137202.
Texto completo da fonteUyeno, Yutaka, Yuji Sekiguchi, Akiko Sunaga, Hiroki Yoshida e Yoichi Kamagata. "Sequence-Specific Cleavage of Small-Subunit (SSU) rRNA with Oligonucleotides and RNase H: a Rapid and Simple Approach to SSU rRNA-Based Quantitative Detection of Microorganisms". Applied and Environmental Microbiology 70, n.º 6 (junho de 2004): 3650–63. http://dx.doi.org/10.1128/aem.70.6.3650-3663.2004.
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