Literatura científica selecionada sobre o tema "Purpurin-18"

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Artigos de revistas sobre o assunto "Purpurin-18"

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Yoon, Il, Ho-Sung Park, Bing Cun Cui, Jung-Hwa Kim, and Young-Key Shim. "Synthesis and Photodynamic Activities of Pyrazolyl and Cyclopropyl Derivatives of Purpurin-18 Methyl Ester and Purpurin-18-N-butylimide." Bulletin of the Korean Chemical Society 32, no. 1 (2011): 169–74. http://dx.doi.org/10.5012/bkcs.2011.32.1.169.

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Pavlíčková, Vladimíra, Jan Škubník, Michal Jurášek, and Silvie Rimpelová. "Advances in Purpurin 18 Research: On Cancer Therapy." Applied Sciences 11, no. 5 (2021): 2254. http://dx.doi.org/10.3390/app11052254.

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How to make cancer treatment more efficient and enhance the patient’s outcome? By multimodal therapy, theranostics, or personalized medicine? These are questions asked by scientists and doctors worldwide. However, finding new unique approaches and options for cancer treatment as well as new selective therapeutics is very challenging. More frequently, researchers “go back in time” and use already known and well-described compounds/drugs, the structure of which further derivatize to “improve” their properties, extend the use of existing drugs to new indications, or even to obtain a completely no
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Pavlíčková, Vladimíra, Silvie Rimpelová, Michal Jurášek, et al. "PEGylated Purpurin 18 with Improved Solubility: Potent Compounds for Photodynamic Therapy of Cancer." Molecules 24, no. 24 (2019): 4477. http://dx.doi.org/10.3390/molecules24244477.

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Purpurin 18 derivatives with a polyethylene glycol (PEG) linker were synthesized as novel photosensitizers (PSs) with the goal of using them in photodynamic therapy (PDT) for cancer. These compounds, derived from a second-generation PS, exhibit absorption at long wavelengths; considerable singlet oxygen generation and, in contrast to purpurin 18, have higher hydrophilicity due to decreased logP. Together, these properties make them potentially ideal PSs. To verify this, we screened the developed compounds for cell uptake, intracellular localization, antitumor activity and induced cell death ty
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Yoon, Il, Ho Sung Park, Bing Cun Cui, Jung Hwa Kim, and Young Key Shim. "ChemInform Abstract: Synthesis and Photodynamic Activities of Pyrazolyl and Cyclopropyl Derivatives of Purpurin-18 Methyl Ester and Purpurin-18-N-butylimide." ChemInform 42, no. 22 (2011): no. http://dx.doi.org/10.1002/chin.201122105.

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Drogat, Nicolas, Matthieu Barrière, Robert Granet, Vincent Sol, and Pierre Krausz. "High yield preparation of purpurin-18 from Spirulina maxima." Dyes and Pigments 88, no. 1 (2011): 125–27. http://dx.doi.org/10.1016/j.dyepig.2010.05.006.

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Liu, Ranran, Jungang Yin, Jiazhu Li, et al. "Halogenation Reaction of Purpurin-18 and Synthesis of Chlorin Derivatives." Chinese Journal of Organic Chemistry 32, no. 03 (2012): 544. http://dx.doi.org/10.6023/cjoc1105231.

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Nguyen, Minh Hieu, Binh Duong Le, Anh Tuan Mai, et al. "Some characteristics of purpurin-18synthesised from chlorophyll a of Spirulina." Ministry of Science and Technology, Vietnam 63, no. 11 (2021): 40–43. http://dx.doi.org/10.31276/vjst.63(11).40-43.

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Research and synthesis of photosensitive purpurin 18 (Pp-18) from nature is one of the topics that many research groups are interested in and developing. In this study, the authors defined some characteristics of Pp-18 synthesised from chlorophyll a - a substance isolated from Spirulina. The results showed that Pp-18 had good dispersion in acetone at 478.5 nm (R2=0.98285) and reached 98%. Fluorescence spectroscopy of Pp-18 in acetone was measured at a concentration of 70 ppm, wavelengths 365.39, 417.62, and 557.96 nm. The fluorescence lifetime of Pp-18 in acetone solution was 2.85 ns.
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Pogorilyy, Viktor, Anna Plyutinskaya, Nikita Suvorov, et al. "The First Selenoanhydride in the Series of Chlorophyll a Derivatives, Its Stability and Photoinduced Cytotoxicity." Molecules 26, no. 23 (2021): 7298. http://dx.doi.org/10.3390/molecules26237298.

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In this work, we obtained the first selenium-containing chlorin with a chalcogen atom in exlocycle E. It was shown that the spectral properties were preserved in the target compound and the stability increased at two different pH values, in comparison with the starting purpurin-18. The derivatives have sufficiently high fluorescence and singlet oxygen quantum yields. The photoinduced cytotoxicity of sulfur- and selenium-anhydrides of chlorin p6 studied for the first time in vitro on the S37 cell line was found to be two times higher that of purpurin-18 and purpurinimide studied previously. Mor
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Bitapi, Mandal, and Das Saurabh. "Electrochemical reduction of purpurin, its Mn(II) complex in DMF and aqueous-DMF mixed solvent: A cyclic voltammetric study." Journal of Indian Chemical Society Vol. 97, No. 12a, Dec 2020 (2020): 2633–42. https://doi.org/10.5281/zenodo.5656100.

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Department of Chemistry (Inorganic Section), Jadavpur University, Kolkata-700 032, India <em>E-mail:</em> dasrsv@yahoo.in <em>Manuscript received online 18 November 2020, revised and accepted 26 December 2020</em> Purpurin studied in pure and aqueous-dimethyl formamide (DMF) medium undergoes successive two one-electron reductions accompanied by comproportionation generating semiquinone radical anion realized by considering either complete reduction of it by two-electrons or reversing the scan immediately after reduction by one electron in cyclic voltammetry experiments. Difference in the oxida
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Liu, Hongyao, Guohua Zhu, Ranran Liu, Yingxue Jin, Caixia Qi, and Jinjun Wang. "Chemical Modifications of Purpurin-18 and Synthesis of Chlorophyllous Chlorins Derivatives." Chinese Journal of Organic Chemistry 35, no. 6 (2015): 1320. http://dx.doi.org/10.6023/cjoc201410003.

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Teses / dissertações sobre o assunto "Purpurin-18"

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Chkair, Rayan. "Utilisation de nouveaux photosensibilisateurs innovant en thérapie photodynamique anticancéreuse dans le traitement du cancer colorectal." Electronic Thesis or Diss., Limoges, 2024. http://www.theses.fr/2024LIMO0094.

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Le cancer colorectal (CCR) est l'une des tumeurs malignes les plus diagnostiquées au monde, et les modalités thérapeutiques conventionnelles actuelles sont souvent invasives, résistantes et induisent des effets secondaires toxiques sur les tissus sains. C’est pourquoi de nouvelles approches thérapeutiques ciblées se développent. Dans cette optique, on trouve la thérapie photodynamique (PDT) qui présente plusieurs avantages évidents par rapport aux modalités classiques, telles qu'une invasivité minimale, une grande sélectivité vis-à-vis des tissus cancéreux et moins d'effets secondaires. La PDT
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