Literatura científica selecionada sobre o tema "Procesi bundles"
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Artigos de revistas sobre o assunto "Procesi bundles"
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Losev, Ivan. "On Procesi bundles". Mathematische Annalen 359, n.º 3-4 (9 de fevereiro de 2014): 729–44. http://dx.doi.org/10.1007/s00208-014-1017-7.
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Ehrig, Michael, e Catharina Stroppel. "2-row Springer Fibres and Khovanov Diagram Algebras for Type D". Canadian Journal of Mathematics 68, n.º 6 (1 de dezembro de 2016): 1285–333. http://dx.doi.org/10.4153/cjm-2015-051-4.
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AbstractWe study in detail two row Springer fibres of even orthogonal type from an algebraic as well as a topological point of view. We show that the irreducible components and their pairwise intersections are iterated ℙ1-bundles. Using results of Kumar and Procesi we compute the cohomology ring with its action of the Weyl group. The main tool is a type D diagram calculus labelling the irreducible components in a convenient way that relates to a diagrammatical algebra describing the category of perverse sheaves on isotropic Grassmannians based on work of Braden. The diagram calculus generalizes Khovanov's arc algebra to the type D setting and should be seen as setting the framework for generalizing well-known connections of these algebras in type A to other types.
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Carroll, Kathryn A., Anya Samek e Lydia Zepeda. "Consumer Preference for Food Bundles under Cognitive Load: A Grocery Shopping Experiment". Foods 11, n.º 7 (27 de março de 2022): 973. http://dx.doi.org/10.3390/foods11070973.
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Product bundling is a common retail marketing strategy. The bundling of food items has the potential to increase profits in the grocery sector, particularly for fresh produce, which often has lower profit margins. Although prior work suggests consumers prefer bundles because they require less cognitive effort to select, no study has yet experimentally manipulated cognitive load when food bundles are included in the choice set. To test whether bundle preference differs when cognitive resources are constrained, a grocery shopping experiment was conducted with 250 consumers in the midwestern U.S., in a laboratory that featured a grocery store display. Consumers who grocery shopped under cognitive load had a higher odds of selecting a food bundle even when the bundle did not offer a price discount. Results suggest food bundles may be preferred because they require less cognitive effort to process, which could benefit consumers by simplifying the grocery shopping experience. Additional factors found to influence food bundle selection included whether the bundled items were perceived as being complementary and hunger levels. Food bundles could help lessen cognitive effort associated with grocery shopping and may especially appeal to those who do not enjoy food shopping.
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Meyer, N., A. N. Hrymak e L. Kärger. "Modeling Short-Range Interactions in Concentrated Newtonian Fiber Bundle Suspensions". International Polymer Processing 36, n.º 3 (1 de julho de 2021): 255–63. http://dx.doi.org/10.1515/ipp-2020-4051.
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Abstract Sheet Molding Compounds (SMC) offer a cost efficient way to enhance mechanical properties of a polymer with long discontinuous fibers, while maintaining formability to integrate functions, such as ribs, beads or other structural reinforcements. During SMC manufacturing, fibers remain often in a bundled configuration and the resulting fiber architecture determines part properties. Accurate prediction of this architecture by simulation of flow under consideration of the transient rheology and transient fiber orientations can speed up the development process. In particular, the interaction of bundles is of significance to predict molding pressures correctly in a direct simulation approach, which resolves individual fiber bundles. Thus, this work investigates the tangential short-range lubrication forces between fiber bundles with analytical and numerical techniques. A relation between the effective sheared gap between bundles and the bundle separation distance at the contact point is found and compared to experimental results from literature. The result is implemented in an ABAQUS contact subroutine to incorporate short-range interactions in a direct bundle simulation framework.
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Harker, Alyssa J., Harshwardhan H. Katkar, Tamara C. Bidone, Fikret Aydin, Gregory A. Voth, Derek A. Applewhite e David R. Kovar. "Ena/VASP processive elongation is modulated by avidity on actin filaments bundled by the filopodia cross-linker fascin". Molecular Biology of the Cell 30, n.º 7 (21 de março de 2019): 851–62. http://dx.doi.org/10.1091/mbc.e18-08-0500.
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Ena/VASP tetramers are processive actin elongation factors that localize to diverse F-actin networks composed of filaments bundled by different cross-linking proteins, such as filopodia (fascin), lamellipodia (fimbrin), and stress fibers (α-actinin). Previously, we found that Ena takes approximately threefold longer processive runs on trailing barbed ends of fascin-bundled F-actin. Here, we used single-molecule TIRFM (total internal reflection fluorescence microscopy) and developed a kinetic model to further dissect Ena/VASP’s processive mechanism on bundled filaments. We discovered that Ena’s enhanced processivity on trailing barbed ends is specific to fascin bundles, with no enhancement on fimbrin or α-actinin bundles. Notably, Ena/VASP’s processive run length increases with the number of both fascin-bundled filaments and Ena “arms,” revealing avidity facilitates enhanced processivity. Consistently, Ena tetramers form more filopodia than mutant dimer and trimers in Drosophila culture cells. Moreover, enhanced processivity on trailing barbed ends of fascin-bundled filaments is an evolutionarily conserved property of Ena/VASP homologues, including human VASP and Caenorhabditis elegans UNC-34. These results demonstrate that Ena tetramers are tailored for enhanced processivity on fascin bundles and that avidity of multiple arms associating with multiple filaments is critical for this process. Furthermore, we discovered a novel regulatory process whereby bundle size and bundling protein specificity control activities of a processive assembly factor.
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Takemura, R., S. Okabe, T. Umeyama e N. Hirokawa. "Polarity orientation and assembly process of microtubule bundles in nocodazole-treated, MAP2c-transfected COS cells." Molecular Biology of the Cell 6, n.º 8 (agosto de 1995): 981–96. http://dx.doi.org/10.1091/mbc.6.8.981.
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Microtubule bundles reminiscent of those found in neuronal processes are formed in fibroblasts and Sf9 cells that are transfected with the microtubule-associated proteins tau, MAP2, or MAP2c. To analyze the assembly process of these bundles and its relation to the microtubule polarity, we depolymerized the bundles formed in MAP2c-transfected COS cells using nocodazole, and observed the process of assembly of microtubule bundles after removal of the drug in cells microinjected with rhodamine-labeled tubulin. Within minutes of its removal, numerous short microtubule fragments were observed throughout the cytoplasm. These short fragments were randomly oriented and were already bundled. Somewhat longer, but still short bundles, were then found in the peripheral cytoplasm. These bundles became the primordium of the larger bundles, and gradually grew in length and width. The polarity orientation of microtubules in the reformed bundle as determined by "hook" procedure using electron microscope was uniform with the plus end distal to the cell nucleus. The results suggest that some mechanism(s) exists to orient the polarity of microtubules, which are not in direct continuity with the centrosome, during the formation of large bundles. The observed process presents a useful model system for studying the organization of microtubules that are not directly associated with the centrosomes, such as those observed in axons.
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Yu, Chongwen, Weiying Tao e Timothy A. Calamari. "Treatment and Characterization of Kenaf for Nonwoven and Woven Applications". International Nonwovens Journal os-9, n.º 4 (dezembro de 2000): 1558925000OS—90. http://dx.doi.org/10.1177/1558925000os-900409.
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A kenaf bast fiber is comprised of a bundle of single fibers bound by lignin and pectins. It offers the advantages of being renewable, biodegradable and environmentally safe. However, it is difficult to process kenaf fibers because of the coarseness, stiffness and low cohesion of the fiber bundles. In this research, kenaf fiber bundles have been treated by both alkaline sulfide and a modified chemical degumming methods to improve fiber properties. Tensile properties, fineness, length and softness of the kenaf fiber bundles after the treatments were determined. It was found that both treatments improved the fiber fineness, softness and elongation; however, fiber bundle strength was decreased. The modified chemical degumming method was more effective. Under the optimum modified chemical degumming condition, the fineness of the kenaf fiber bundle was improved more than 50% and the fiber bundle was more than twice as soft as the raw material. These kenaf fiber bundles were much finer and softer and found to be easier to process than those obtained in earlier studies. The treated kenaf fiber bundles can be blended with cotton fibers and easily carded on a cotton card with minimum losses. The carded batts can be further processed for either nonwoven or woven applications.
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Khoury, Zana, Mariam Maloyan, Kathleen Conroy e Alexandra Epee-Bounya. "Improving delivery of preventative care services using population management strategies". BMJ Open Quality 11, n.º 2 (maio de 2022): e001695. http://dx.doi.org/10.1136/bmjoq-2021-001695.
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BackgroundConsistent and timely delivery of comprehensive preventative care services is a challenge, particularly in underserved patient populations. Previous quality improvement (QI) research has focused on the development of bundled measures of preventative services delivery, but these bundles have not been studied on a population level. We aimed to improve preventative care service delivery on a clinic population level through the use of a bundled measure that includes immunisations, lead screening and use of screening tools among underserved patients under 2 years old.MethodsA QI study was conducted at a community-based academic primary care clinic. A population-level bundled measure was adapted from an existing tool. We used plan–do–study–act cycles to optimise results and tracked bundle outcome rates using a p-type statistical process control chart. Interventions included (1) staff education on measure components, (2) introduction of exam room-based phlebotomy to address lead screening completion rates and (3) population management strategies, including development of a patient registry and use of reminders and visit tracking to increase attendance at well-child visits.ResultsThe percent of bundle completion by 14 months of age increased from a baseline of 58%–77% following implementation of the QI initiatives. A mean shift was identified after the population manager began proactive targeted outreach for the 12-month visit.ConclusionTargeted systems for outreach aimed at bringing patients into the clinic and patient-centred strategies for visit completion are effective at ensuring timely delivery of comprehensive preventative care to an underserved paediatric population.
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Tilney, Lewis G., Patricia S. Connelly, Kelly A. Vranich, Michael K. Shaw e Gregory M. Guild. "Regulation of Actin Filament Cross-linking and Bundle Shape in Drosophila Bristles". Journal of Cell Biology 148, n.º 1 (10 de janeiro de 2000): 87–99. http://dx.doi.org/10.1083/jcb.148.1.87.
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Previous studies demonstrate that in developing Drosophila bristles, two cross-linking proteins are required sequentially to bundle the actin filaments that support elongating bristle cells. The forked protein initiates the process and facilitates subsequent cross-linking by fascin. Using cross-linker–specific antibodies, mutants, and drugs we show that fascin and actin are present in excessive amounts throughout bundle elongation. In contrast, the forked cross-linker is limited throughout bundle formation, and accordingly, regulates bundle size and shape. We also show that regulation of cross-linking by phosphorylation can affect bundle size. Specifically, inhibition of phosphorylation by staurosporine results in a failure to form large bundles if added during bundle formation, and leads to a loss of cross-linking by fascin if added after the bundles form. Interestingly, inhibition of dephosphorylation by okadaic acid results in the separation of the actin bundles from the plasma membrane. We further show by thin section electron microscopy analysis of mutant and wild-type bristles that the amount of material that connects the actin bundles to the plasma membrane is also limited throughout bristle elongation. Therefore, overall bundle shape is determined by the number of actin filaments assembled onto the limited area provided by the connector material. We conclude that assembly of actin bundles in Drosophila bristles is controlled in part by the controlled availability of a single cross-linking protein, forked, and in part by controlled phosphorylation of cross-links and membrane actin connector proteins.
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Budnik, Pavel, Ilya Shegelman e Vyacheslav Baklagin. "Variability of forwarder truckload parameters in the Pryazha forestry division of the Republic of Karelia (Russia): A computer experiment". Central European Forestry Journal 66, n.º 1 (1 de março de 2020): 12–22. http://dx.doi.org/10.2478/forj-2019-0027.
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AbstractThe goal of the present research is to analyze parameters of a bundle of logs for various models of forwarders in the Pryazha division of forestry of the Republic of Karelia. The investigated parameters were mass and volume of a bundle of logs, stacking factor of the bundle and the number of wood assortments in the bundle. The following models of forwarders have been investigated: John Deere 1210E, John Deere 1110E, Ponsse Elk, Ponsse Wisent, Amkodor 2661-01, Rottne F13D, Rottne F15D, Rottne F18D. We estimated the parameters of bundles formed from spruce sawlog 6.1 m long and bundles formed from spruce pulpwood 4 m long. Data on stem forms from harvester recorders have been collected to assess the parameters of a bundle of logs. Parameters of bundles have been determined based on computer experiment. The experiment consists of the following steps: random selection of the stem from the database; simulation of the cut-to-length process; simulation of log stacking process; calculation of parameters of a bundle of logs. We found that parameters of bundles vary to a quite substantial extent. Average variability of a bundle of logs formed of 6.1 m long spruce sawlog is 4.5 t, variability of the volume is 5.8 m3, and variability of the number of wood assortments in a bundle is 49 pcs. For a bundle made up of 4 m long spruce pulpwood variability of mass is on average 2.8 t, that of volume – 2.09 m3, that of the number of wood assortments – 57 pc. The presented results can inform transportation of wood on cutting areas, planning timber harvesting, as well as development new logging machines.
Teses / dissertações sobre o assunto "Procesi bundles"
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Paegelow, Raphaël. "Action des sous-groupes finis de SL2(C) sur la variété de carquois de Nakajima du carquois de Jordan et fibrés de Procesi". Electronic Thesis or Diss., Université de Montpellier (2022-....), 2024. http://www.theses.fr/2024UMONS005.
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Dans cette thèse de doctorat, nous avons, dans un premier temps, étudié la décomposition en composantes irréductibles du lieu des points fixes sous l’action d’un sous-groupe fini Γ de SL2(C) de la variété de carquois de Nakajima du carquois de Jordan. La variété de carquois associé au carquois de Jordan est isomorphe soit au schéma ponctuel de Hilbert dans C2 soit à l’espace de Calogero-Moser. Nous avons décrit ces composantes irréductibles à l’aide de variétés de carquois du carquois de McKay associé au sous-groupe fini Γ. Nous nous sommes ensuite intéressés à la combinatoire découlant de l’ensemble d’indexation de ces composantes irréductibles en utilisant une action du groupe de Weyl affine introduite par Nakajima. De plus, nous avons construit un modèle combinatoire lorsque Γ est de type D, qui est le seul cas original et remarquable. En effet, si Γ est de type A, un tel travail a déjà été fait par Iain Gordon et si Γ est de type E, nous avons montré que les points fixes qui sont aussi des points fixes du tore diagonal maximal de SL2(C) sont les idéaux monomiaux du schéma ponctuel de Hilbert dans C2 indexés par les partitions en escaliers. De manière plus précise, si Γ est de type D, nous avons obtenu un modèle de l’ensemble indexant les composantes irréductibles contenant un point fixe du tore maximal diagonal de SL2(C) en termes de partitions symétriques. Enfin, si n est un entier plus grand que 1, en utilisant la classification des résolutions projectives et symplectiques de la singularité (C2)n/Γn où Γn est le produit en couronne du groupe symétrique Sn des n premiers entiers et de Γ, nous avons obtenu une description de toutes ces résolutions projectives et symplectiques en termes de composantes irréductibles du lieu des Γ-points fixes du schéma ponctuel de Hilbert dans C2.Dans un second temps, nous nous sommes intéressés à la restriction de deux fibrés vectoriels au-dessus d’une composante irréductible du lieu des Γ-points fixes du schéma de Hilbert dans C2 fixée. Le premier fibré est le fibré tautologique dont nous avons exprimé la restriction en termes de fibrés tautologiques de Nakajima sur la variété de carquois du carquois de McKay associée à la composante irréductible fixée. Le second fibré vectoriel est le fibré de Procesi. Ce fibré a été introduit par Marc Haiman dans ces travaux démontrant la conjecture n!. Nous avons étudié les fibres de ce fibré en tant que (Sn × Γ)-module. Dans la première partie du chapitre de cette thèse consacré au fibré de Procesi, nous avons démontré un théorème de réduction qui exprime le (Sn × Γ)-module associé à la fibre de la restriction du fibré de Procesi au-desus d’une composante irréductible C du lieu des Γ-points fixes du schéma de Hilbert de n points dans C2 comme l’induit de la fibre de la restriction du fibré de Procesi au-dessus d’une composante irréductible du lieu des Γ-points fixes du schéma de Hilbert de k points dans C2 où l’entier k ≤ n est explicite et dépend de la composante irréductible C et de Γ. Ce théorème est ensuite démontré avec d’autres outils dans deux cas particuliers pour Γ de type A. Enfin, lorsque Γ est de type D, certaines formules explicites de réduction des fibres de la restriction du fibré de Procesi au lieu des Γ-point fixes ont étéobtenues.Pour finir, si l est un entier plus grand que 1, alors dans le cas où Γ est le sous-groupe cyclique d’ordre l contenu dans le tore maximal diagonal de SL2(C) noté µl, le théorème de réduction restreint l’étude des fibres du fibré de Procesi au-dessus du lieu des µl-points fixes du schéma ponctuel de Hilbert dans C2 à l’étude des fibres au-dessus des points du schéma de Hilbert associés aux idéaux monomiaux paramétrés par les l-cœurs. Les (Sn × µl)-modules que l’on obtient semble être reliés à l’espace de Fock de l’algèbre de Kac-Moody ˆsll(C). Une conjecture dans ce sens est énoncée dans le dernier chapitreIn this doctoral thesis, first of all, we have studied the decomposition into irreducible components of the fixed point locus under the action of Γ a finite subgroup of SL2(C) of the Nakajima quiver variety of Jordan’s quiver. The quiver variety associated with Jordan’s quiver is either isomorphic to the punctual Hilbert scheme in C2 or to the Calogero-Moser space. We have described the irreducible components using quiver varieties of McKay’s quiver associated with the finite subgroup Γ. We were then interested in the combinatorics coming out of the indexing set of these irreducible components using an action of the affine Weyl group introduced by Nakajima. Moreover, we have constructed a combinatorial model when Γ is of type D, which is the only original and remarkable case. Indeed, when Γ is of type A, such work has already been done by Iain Gordon and if Γ is of type E, we have shown that the fixed points that are also fixed under the maximal diagonal torus of SL2(C) are the monomial ideals of the punctual Hilbert scheme in C2 indexed by staircase partitions. To be more precise, when Γ is of type D, we have obtained a model of the indexing set of the irreducible components containing a fixed point of the maximal diagonal torus of SL2(C) in terms of symmetric partitions. Finally, if n is an integer greater than 1, using the classification of the projective, symplectic resolutions of the singularity (C2)n/Γn where Γn is the wreath product of the symmetric group on n letters Sn with Γ, we have obtained a description of all such resolutions in terms of irreducible components of the Γ-fixedpoint locus of the Hilbert scheme of points in C2.Secondly, we were interested in the restriction of two vector bundles over a fixed irreducible component of the Γ-fixed point locus of the punctual Hilbert scheme in C2. The first vector bundle is the tautological vector bundle that we have expressed the restriction in terms of Nakajima’s tautological vector bundle on the quiver variety of McKay’s quiver associated with the fixed irreducible component. The second vector bundle is the Procesi bundle. This vector bundle was introduced by Marc Haiman in his work proving the n! conjecture. We have studied the fibers of this bundle as (Sn × Γ)-module. In the first part of the chapter of this thesis dedicated to the Procesi bundle, we have shown a reduction theorem that expresses the (Sn × Γ)-module associated with the fiber of the restriction of the Procesi bundle over an irreducible component C of the Γ-fixed point locus of Hilbert scheme of n points in C2 as the induced of the fiber of the restriction of the Procesi bundle over an irreducible component of the Γ-fixed point locus of the Hilbert scheme of k points in C2 where k ≤ n is explicit and depends on the irreducible component C and Γ. This theorem is then proven with other tools in two edge cases when Γ is of type A. Finally, when Γ is of type D, some explicit reduction formulas of the restriction of the Procesi bundle to the Γ-fixed point locus have been obtained.To finish, if l is an integer greater than 1, then in the case where Γ is the cyclic group of order l contained in the maximal diagonal torus of SL2(C) denoted by µl, the reduction theorem restricts the study of the fibers of the Procesi bundle over the µl-fixed points of the punctual Hilbert scheme in C2 to the study of the fibers over points in the Hilbert scheme associated with monomial ideals parametrized by the l-cores. The (Sn × Γ)-module that one obtains seems to be related to the Fock space of the Kac-Moody algebra ˆsll(C). A conjecture in this direction has been stated in the last chapter
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Linga, Gaute. "The Breaking Process of an Idealized Polymeric Bundle under Applied Tensile Stress". Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for fysikk, 2014. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-26873.
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We introduce a particle-based model of an idealized polymeric bundle, whose properties are investigated by means of molecular dynamics simulations. We analyse in particular the effect of applying a tensile stress, stretching and eventually breaking the bundle.The simulation results show that, despite its simplicity, the model captures characteristic features of polymeric materials, e.g. a multistage creep and creep ringing. The results indicate that the system evolves in a near-equilibrium state during almost the entire creep process, reflected in the data collapse of the \emph{effective stress--strain} curve.Two distinct variants of the basic model are studied, the first one allowing and the second one disallowing recombination of broken bonds. The former model is observed to undergo a phase transition, taking place at a critical tensile force $F_c$. Below this threshold, the bundle is observed to stabilize, and above the threshold, the bundle breaks down. In both model assumptions, the bundle lifetime $t_f$ seems to exhibit Basquin-like power-law dependence upon the applied force $F$; for the former this is estimated to be $t_f \sim F^{-\gamma}$, with $\gamma = 4 \pm 0.1$. Simulation results follow the same power law over the accessible range in $F$, spanning about half a decade.The elongation difference as a function of normalized time also shows a remarkable data collapse for a range in $F$, hinting to universality in the creep process. Moreover, at imminent failure, the strain rate is shown to grow as $\dot{L} \sim \tau_{\rm ttf}^{-1}$, where $\tau_{\rm ttf}$ is the normalized time-to-failure. This is in excellent agreement with recent experimental findings for a protein gel \cite{leocmach2014creep}.New theoretical approaches are also made to understand the breaking process of a bundle of polymers. In particular, a simple one-step fiber bundle model is proposed. The model may serve to explain the phase transition that was observed for the simulation model that allowed for recombination.
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Judd, Vaughan C. (Vaughan Charles). "An Exploratory Study of the Information Search Stage of the Consumer Decision Process: Based on Elderly Consumers' Selection of a New Housing Bundle". Thesis, University of North Texas, 1993. https://digital.library.unt.edu/ark:/67531/metadc278396/.
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This dissertation deals with the decision-to-move process of elderly persons—from a marketer's perspective. The central problem addressed is the lack of empirical knowledge concerning the factors and influences associated with the information search process of elderly persons in making a residential move decision. The purpose was to investigate and understand the key factors and influences which are viewed as important by elderly individuals in their search for and use of information.
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Calil, Keila. "Construção de um bundle para um manuseio do cateter venoso central: pesquisa baseada em evidência". Universidade Federal Fluminense, 2014. https://app.uff.br/riuff/handle/1/841.
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Mestrado Profissional em Enfermagem Assistencial
Problema: O objeto deste estudo apresenta-se pelas evidências científicas para a prevenção de Infecção Primária de Corrente Sanguínea (IPCS) em pacientes em uso do Cateter Venoso Central (CVC). A IPCS representa um dos principais problemas da assistência à saúde, com consequente impacto na morbidade e mortalidade dos pacientes, principalmente, daqueles que em decorrência da gravidade de sua doença, necessitam de um CVC. Muito se tem discutido, recentemente, acerca da segurança do paciente e reavaliar as práticas assistenciais prestadas com a utilização de um conjunto de boas práticas denominado "bundles", é uma orientação para redução dessas infecções. Objetivos: Construir um bundle para prevenção de Infecção Primária de Corrente Sanguínea (IPCS) no manuseio do Cateter Venoso Central (CVC). Descrever as evidências científicas para prevenção de IPCS em pacientes em uso do CVC estabelecendo padrões para as ações de enfermagem referente à prevenção dessas infecções. Elaborar critérios de avaliação das ações de enfermagem com vistas à prevenção de IPCS em pacientes em uso do CVC. Método: Pesquisa Baseada em Evidência (PBE) com a utilização de diretrizes nacional e internacional. Resultados e Discussão: Em virtude da necessidade de prevenção e controle das IRAS (Infecções Relacionadas à Assistência à Saúde), podem-se considerar as diretrizes que abordam este tema como guia para a prática de um cuidado seguro para os pacientes uma vez que estas concentram na descrição das ações de prevenção o melhor nível de evidência disponível e de forma atualizada. Especificamente sobre a IPCS em pacientes em uso do CVC, salienta-se a importância das ações de prevenção serem praticadas em conjunto e ao mesmo tempo serem passíveis de avaliação com o objetivo de repensar o cuidado dispensado aos pacientes e educar a equipe de enfermagem para melhores práticas assistenciais. Dentro deste contexto a construção do bundle para manuseio do CVC apresenta-se como objeto e para construí-lo foram examinadas as diretrizes para prevenção de IPCS em pacientes em uso do CVC e redefinidas as ações de enfermagem para uma adequação à realidade que se pretende intervir. Por conseguinte, foram estabelecidos os padrões de cuidado para que assim fossem elaborados os critérios de avaliação para as ações de enfermagem que compõem o bundle. É possível, dessa maneira, visualizar o bundle como um instrumento para orientação, avaliação e melhoria do cuidado referente às ações como a higienização das mãos antes e após o manuseio do CVC e do sistema de infusão, uso de luvas não estéreis e desinfecção das conexões antes de serem acessadas, troca do sistema de infusão no tempo adequado com identificação da data, troca correta do curativo do sítio de inserção do CVC e documentação da avaliação diária do sítio de inserção do CVC. Considerações Finais: Pode-se afirmar que a melhor evidência científica para atuar na prevenção da IPCS em pacientes em uso do CVC se encontram nas diretrizes do Centers for Disease Control and Prevention (CDC). Entretanto, não é possível desconsiderar as diretrizes da Agência Nacional de Vigilância Sanitária (ANVISA) uma vez que dados da realidade do Brasil junto à realidade de um serviço específico são fatores determinantes para o sucesso de uma estratégia de melhoria. Contribuir para que os Enfermeiros e Técnicos de Enfermagem que atuam em UTI de adultos permaneçam familiarizados com as evidências científicas para prevenção de IPCS em pacientes em uso do CVC e se comprometam em executar estas ações é uma das formas de envolver os recursos humanos no propósito de modificar uma realidade e contribuir para uma assistência de enfermagem mais uniforme no que diz respeito à teoria e prática. Significa entender a importância da enfermagem para a prevenção e controle de infecções e incentivar a busca por novos conhecimentos. Entende-se que, mostrar para esses profissionais como se apresenta a prática do cuidado da equipe de enfermagem é um aspecto decisivo para repensar a prática e encontrar um caminho em busca da segurança do paciente.
Problem: The object of this study presents the scientific evidences for the prevention of primary bloodstream infections in patients using central venous catheter (CVC). The IPCS is a major problem in health care, with consequent impact on morbidity and mortality of patients, mainly for those needs a CVC due the severity of their condition. Recently, much has been discussed about the safety of the patient and to reassess the care practices provided using a set of best practices called "bundles" is an orientation to reducing these infections. Aims: Build a Bundle for prevention of IPCS in handling CVC. Describe the scientific evidences for the prevention of IPCS in patients using CVC establishing standards for nursing actions related to the prevention of these infections. Develop evaluation criteria of nursing actions aimed at preventing IPCS in patients using CVC. Method: Evidence-Based Research (EBR) with the use of national and international guidelines. Results and Discussion: Because of the need for prevention and control of Prevent Health Care-Associated Infections (HAIs), the guidelines that address this issue may be considered as a guide to safe care practice for patients, since on description of prevention they focus the best level of evidence available and updated form. Specifically on the IPCS in patients using CVC emphasizes the importance of prevention being practiced together while being assessable in order to rethink the care given to patients and educating nursing staff for best assistance practices. Within this context, the construction of the bundle for handling the CVC presents itself as an object and to build it were examined IPCS guidelines for prevention in patients using CVC and nursing actions were redefined for adaptation to the reality that if you want to intervene. Subsequently were established the patterns of care for after develop evaluation criteria for nursing actions that make up the bundle. Thus, it’s possible to view the bundle as a tool for guidance, evaluation and improvement of care relating to actions such as washing hands before and after handling the CVC and the infusion system, use of non-sterile gloves and disinfecting of the connections before to access them, exchange of the infusion system at the appropriate time with identify the date, correctly replacement of the bandage of the insertion site of CVC and documentation of the daily assessment of the site of insertion of the CVC. Final Thoughts: It can be argued that the best scientific evidences for the early prevention of IPCS in patients using CVC are the guidelines of the Centers for Disease Control and Prevention (CDC). However, it is not possible to disregard the guidelines of the National Health Surveillance Agency (ANVISA, in Portuguese), since data from the reality of Brazil and the reality of a particular service are crucial to the success of an improvement strategy. Contribute to the nurses and nursing technicians who work in the adult ICU remain familiar with the scientific evidence for the prevention of IPCS in patients using CVC and commit themselves to perform these actions is one way to involve human resources in order to modifying a reality and contribute to a more uniform nursing assistance regarding the theory and practice. Means understanding the importance of nursing for the prevention and control of infections and encourage the search for new knowledge. It is understood that, to show for these professionals as the care practice of the nursing staff presents is a critical aspect to rethink the practice and find a path in search of the patient safety.
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Villette, François. "Endommagement de milieux hétérogènes : Le papier en tant que matériau modèle". Thesis, Université Grenoble Alpes, 2020. http://www.theses.fr/2020GRALI062.
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La compréhension, la modélisation et la prévision de la rupture dans les matériaux hétérogènes sont des enjeux importants pour de nombreuses applications comme la résistance des structures de génie-civil ou les détachements de blocs rocheux par exemple. Actuellement, la modélisation de la fissuration dans les modèles d’endommagement fait intervenir une longueur interne qui n’est pas encore reliée explicitement aux longueurs caractéristiques du matériau. L’objectif de ce travail est d’étudier l’influence des hétérogénéités du matériau sur les processus de fissuration en utilisant le papier comme matériau d’étude. Ce matériau a en effet la propriété de révéler sa structure (fibres et agrégats de fibres) par transmission optique et permet ainsi de suivre l’évolution de l’endommagement au cours de la rupture à moindres coûts. Dans un premier temps, les propriétés structurales et mécaniques locales des agrégats de fibres ont été obtenues à partir d’images acquises par tomographie à rayons X et d’essais de tractions. Des essais de traction filmés ont ensuite permis de visualiser le développement de la zone d’endommagement et de relier ses dimensions au comportement post-pic de la courbe de traction. Sur la base de cette analyse, une méthode originale de calage de la longueur interne a été proposée sur un modèle d’endommagement continu non local. Le rôle des différentes longueurs caractéristiques du matériau a été mis en évidence par ces résultats qui ont été complétés par une étude de la statistique de propagation de fissure dans un matériau hétérogène en utilisant un Fiber Bundle Model (modèle à faisceaux de fibres), que nous avons dans le cadre de cette thèse étendu à des champs aléatoires de rupture corrélés dans l’espaceThe understanding, modeling and prediction of failure in heterogeneous materials are important issues for many applications such as the resistance of civil engineering structures or rock detachments for example. Currently, damage models involve an internal length that is not yet explicitly related to the characteristic lengths of the material. The objective of this work is to study the influence of material heterogeneities on cracking processes using paper as a model material. Indeed, this material has the property to reveal its structure (fibers and fiber aggregates) by optical transmission and thus allows following the evolution of the damage during the rupture at lower costs. In a first step, the local structural and mechanical properties of the fiber aggregates were obtained from images acquired by X-ray tomography and tensile tests. Filmed tensile tests were then used to visualize the development of the fracture process zone and to relate its dimensions to the post-peak behaviour of the tensile curve. On the basis of this analysis, a novel method of calibration of the internal length was proposed on a non-local continuous damage model. The role of the different characteristic lengths of the material was highlighted by these results which were complemented by a study of the crack propagation statistics in a heterogeneous material using a Fiber Bundle Model that we have extended to spatially correlated random fields of rupture
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Heck, Guilherme. "The impact of voltage scaling over delay elements with focus on post-silicon tests". Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2018. http://tede2.pucrs.br/tede2/handle/tede/8254.
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A demanda sem precedentes por poderosos dispositivos de processamento gerou quebras consecutivas de paradigma de projeto de circuito na ?rea de Circuitos Integrados (CIs). O uso de tecnologia submicrom?trica profunda aumenta a densidade de integra??o a n?veis nunca vistos antes. No entanto, com CIs mais densos, a inclina??o do rel?gio e outros efeitos requerem compensa??es em design s?ncrono, o que pode aumentar a ?rea e o consumo de energia a valores inaceit?veis. Como alternativa, o paradigma ass?ncrono est? re-emergindo, focado na efici?ncia de energia. Entre os modelos cl?ssicos de projeto ass?ncrono, o Empacotamento-de-Dados (ED) se destaca pela sua capacidade de fornecer alto desempenho, reduzir a pot?ncia e obter resultados de ?rea semelhante ? dos modelos s?ncronos. Diferentemente dos modelos mais robustos de quase-atraso insens?vel, uma outra classe comum de modelos para implementar circuitos ass?ncronos, circuitos ED requerem o uso extensivo de Elementos de Atraso (EAs) para garantir a correta funcionalidade. No entanto, todos os circuitos s?o afetados por varia??es de Processo, Tens?o e Temperatura (PTT), incluindo a L?gica Combinacional (LC) em ED impondo margem em elementos de atraso. Al?m disso, projetos atuais usam escalonamento de tens?o para melhorar a efici?ncia de energia, o que afeta o atraso diferentemente em LCs e EAs adicionando mais margem em EAs. Um novo modelo baseado em ED chamado Blade usa o conceito de resili?ncia como uma esperan?a para evitar a margem de atraso causada por PTT e escalonamento de tens?o. Contudo, o uso de dois elementos de atraso ir? representar mais margens e mais tempo de teste no circuito final. Assim, este trabalho mostra uma an?lise do comportamento de elementos de atraso sob escalonamento de tens?o e o impacto em testes p?s-sil?cio. Ele introduz um novo termo para determinar o impacto da escala de tens?o sobre os elementos de atraso e tamb?m a compara??o entre os EAs mais utilizados em projetos ED usando esta nova m?trica. Uma an?lise de testes em modelos ED e Blade ? apresentada e o impacto da escala de tens?o nestes projetos ? analisado. Finalmente, um novo elemento de atraso ? proposto focando na redu??o de margem e redu??o no tempo de teste para o modelo Blade.
The unprecedented demand for powerful processing devices has generated consecutive circuit design paradigm breaks in the Integrated Circuits (ICs) arena. The use of deep submicron technology increases the integration density to levels never seen before. However, with denser ICs, clock skew and other effects require compensations in synchronous design, which can increase area overhead and power consumption to unacceptable values. As an alternative, the asynchronous paradigm is re-emerging, focused on power efficiency. Among classical asynchronous design templates, the Bundled-Data (BD) one stands off for its capability to provide high performance, reduce power and achieve area results similar to that of synchronous designs. Unlike the more robust Quasi-Delay Insensitive (QDI) templates, another common class of templates to implement asynchronous circuits, BD circuits require the extensive use of Delay Elements (DEs) to guarantee correct functionality. However, all circuits are affected by Process, Voltage and Temperature (PVT) variations, including the Combinational Logic (CL) on BD imposing margin on delay elements. In addition, current designs use voltage scaling to improve power efficiency, which impacts the delay differently in CLs and DEs adding more margin in DEs. A new template based on BD called Blade uses resiliency concept as a hope to avoid the delay margin caused by PVT and voltage scaling. Although, the use of two delay elements will represents more margins and extra test time on final circuit. So, this work shows an analysis of delay elements behavior under voltage scaling and the impact on post-silicon tests. It introduces a new term to determine the voltage scaling impact on delay elements and also the comparison between the most used DEs on BD designs using this novel metric. An analysis of tests in BD and Blade templates are presented and the impact of voltage scaling in these designs is analyzed. Finally, a novel delay element is proposed focusing in margin reduction and reduction in test time for Blade template.
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von, Wenckstern Michael. "Web applications using the Google Web Toolkit". Master's thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2013. http://nbn-resolving.de/urn:nbn:de:bsz:105-qucosa-115009.
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This diploma thesis describes how to create or convert traditional Java programs to desktop-like rich internet applications with the Google Web Toolkit. The Google Web Toolkit is an open source development environment, which translates Java code to browser and device independent HTML and JavaScript. Most of the GWT framework parts, including the Java to JavaScript compiler as well as important security issues of websites will be introduced. The famous Agricola board game will be implemented in the Model-View-Presenter pattern to show that complex user interfaces can be created with the Google Web Toolkit. The Google Web Toolkit framework will be compared with the JavaServer Faces one to find out which toolkit is the right one for the next web projectDiese Diplomarbeit beschreibt die Erzeugung desktopähnlicher Anwendungen mit dem Google Web Toolkit und die Umwandlung klassischer Java-Programme in diese. Das Google Web Toolkit ist eine Open-Source-Entwicklungsumgebung, die Java-Code in browserunabhängiges als auch in geräteübergreifendes HTML und JavaScript übersetzt. Vorgestellt wird der Großteil des GWT Frameworks inklusive des Java zu JavaScript-Compilers sowie wichtige Sicherheitsaspekte von Internetseiten. Um zu zeigen, dass auch komplizierte graphische Oberflächen mit dem Google Web Toolkit erzeugt werden können, wird das bekannte Brettspiel Agricola mittels Model-View-Presenter Designmuster implementiert. Zur Ermittlung der richtigen Technologie für das nächste Webprojekt findet ein Vergleich zwischen dem Google Web Toolkit und JavaServer Faces statt
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Gomes, Marta Teixeira Frazão. "The effect of anchoring in product bundles". Master's thesis, 2017. http://hdl.handle.net/10400.14/26226.
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The anchoring effect can be defined as the first piece of information decision makers have access to, which will influence the future choices they make. Despite the extensive literature on this issue covering a wide range of fields, little research has been done regarding the effect of anchoring in product bundles’ evaluation. Given so, the aim of this research is focused on investigating if the order of presentation of the most expensive item results in different perceptions of the overall bundle evaluation. As an extra analysis, it is intended to know if demographic variables namely age, gender and level of education have an impact on the previously stated relation. According to the results, the anchoring effect, predicted in most literature, could not be replicated in this study. However, studies show that individuals with high levels of product familiarity are less influenced by anchors. Given the high levels of product familiarity of the sample of this study, the author believes that was the reason for the lack of effect of the anchoring phenomenon. Indeed there are features that can weaken the some presumably vigorous anchoring effect which is why it is crucial for sales’ people and organizations in general to have a clear understanding of how the anchoring effect plays in consumers’ decision making process and the way individuals evaluate their offers.O efeito da ancoragem pode ser definido como a primeira fonte de informação a que consumidores têm acesso e que influenciará as suas futuras escolhas. Apesar da extensa literatura sobre esta questão que abrange uma ampla gama de áreas de estudo, poucas pesquisas foram feitas sobre o efeito da ancoragem na avaliação dos pacotes de produtos. Posto isto, o objetivo deste estudo centra-se em testar se a ordem de apresentação do item mais caro, considerado também o mais importante, resulta em diferentes avaliações dos pacotes de produtos. Como uma análise extra, pretende-se saber se as variáveis demográficas nomeadamente, idade, género e o nível de educação, têm um impacto na relação anteriormente mencionada. De acordo com os resultados, o efeito de ancoragem, previsto na maioria da literatura, não foi replicado neste estudo. No entanto, estudos mostram que, indivíduos com altos níveis de familiaridade com o produto são menos influenciados pelo efeito da ancoragem. Dado os altos níveis de familiaridade do produto que a amostra deste estudo apresenta, o autor acredita que esse foi o motivo pela falta de influência do efeito da ancoragem. Na verdade, existem características que podem enfraquecer o presumivelmente vigoroso efeito da ancoragem e por essa razão é crucial que as pessoas e as organizações de vendas em geral tenham uma compreensão clara do papel do efeito de ancoragem no processo de tomada de decisão dos consumidores e como estes avaliam as ofertas em seu redor.
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Dzurenko, Miroslav. "Řešení konfiguračního katalogu produktů". Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-320995.
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Market segmentation is growing as customers become more and more demanding for individual products and exclusive services. Companies are introducing new applications and products across many industries , that can be tailored easily to specific customers and markets. To be successful, the organisations have to offer a high level of customisation and customer-centric processes. However, traditional companies in financial, telecommunication and insurance industry struggle with the technological challenges associated with becoming customer focused enterprises. The aim of this thesis is to define the products catalogue framework, that will provide products bundling and customisation capabilities with user-friendly GUI. Therefore, the most of the work can be designed by business users without additional intensive development efforts. Moreover, the viability of the framework was evaluated on the solution based on IBM technologies. Powered by TCPDF (www.tcpdf.org)
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Yen, Shih-Hsiung, e 顏士雄. "Application of the API RP 581 Risk-Based Inspection Technology On the Heat Exchange Tube Bundles in Petro-Chemical Process Systems". Thesis, 2012. http://ndltd.ncl.edu.tw/handle/auum9j.
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碩士國立虎尾科技大學
航空與電子科技研究所
100
The purpose of this research is to predict the failure timing of heat exchanger bundles and evaluate the optimal equipment inspection and replacement cycle through a risk assessment inspection technique developed by the American Petroleum Institute (API). The technique is validated with a simulated petrochemical industry operation. Heat exchanger plays a very important role in the fuel-refining process. Due to the corrosion from corrosive components and the erosion from fine solid particles in crude oil and refrigerant, the thickness of pipe wall of heat exchangers pipelines will gradually thin out, resulting in wall rupture, which in turns calls for an unscheduled maintenance. Since the unscheduled inspection, maintenance and component replacement of the equipments incurred by the unexpected failure often lead to huge out-of-production loss, let alone the potential industrial safety and ecological concerns which should not be ignored. In view of this context, this study, focusing on the consideration of reliability and maintenance cost, applies the API RP 581 risk-based inspection technology to predict the useful life and assess the optimal replacement timing of the heat exchange tube bundles. Weibull distribution function is adopted to simulate the failure model. Through input of historical data of when specific heat exchanger tube bundles were inspected and/or replaced, the reliability life of current heat exchanger equipment is predicted. The results show that the Weibull failure distribution function model to estimate the bundle mean time to failure MTTF (Mean Time To Failure)reference more data, more accurate life assessment; The consequences of failure to bundle conduct a risk assessment, unplanned maintenance costs and a planned maintenance cost of the gap can be calculated through the maintenance of the number of days, results can be displayed to bundle the consequences of failure analysis to predict the effective bundle the optimal replacement time; Will bundle the consequences of failure analysis with the rate of return ROR parameters in accordance with the inspection data to determine the bundle whether the repair or replacement, the longer distance to replace equipment in case the higher the rate of return ROR; Can estimate the bundle life and control of the replacement time, according to the different definitions of the minimum wall thickness available, can affect the service life of heat exchanger tube bundle heat exchanger wall; This result represents the wall thickness is a very important factor in the life of the bundle replacement time to grasp the precise bundle of data with the risk assessment period can improve the cost of operation and service life of the heat exchanger.
Livros sobre o assunto "Procesi bundles"
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Zimmermann, Peter. Rechte und Rechtsschutz im Verfahren parlamentarischer Untersuchungskommissionen des Bundes. Basel: Helbing & Lichtenhahn, 1992.
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Gerverdinck, Tjebbe. Wetenschappelijk bijdragen: Bundel ter gelegenheid van het 35-jarig bestaan van het wetenschappelijk bureau van de Hoge Raad der Nederlanden. Den Haag: Boom Juridische uitgevers, 2014.
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M, Boek J. L., ed. Grensoverschrijdend strafrecht: Een bundel opstellen geschreven door medewerkers van de Afdeling Straf(proces)recht, Rijksuniversiteit te Leiden. Arnhem: Gouda Quint, 1990.
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Aspelund, Karl. Design Process: Bundle Book + Studio Access Card. Fairchild Books, 2022.
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Bedock, Camille. Bundling the Bundles. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198779582.003.0009.
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The failed constitutional reform and the successful electoral reform occurring in Italy between 2003 and 2006 constitute archetypical examples of the dynamics behind divisive institutional reforms conducted through a majoritarian process. The main argument of this chapter is that the very presence of four coalition partners with different priorities has led to the formulation and negotiation of an ever wider bundle of institutional reforms. First, this large bundle has been built in order to accommodate the diverging priorities and preferences of the government coalition by giving something to each party. Second, the very dynamic of trade-offs and the anticipation of the effects of the reforms have led the reformers to include more and more provisions in the deal, eventually evidencing the crucial importance of time management in the final outcome of the two reforms.
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Adler's Interplay: Process of Interpersonal Communication 8E, bundled with Glaser's Understanding Style: Practical Ways to Improve Your Writing: Bundle. 8a ed. Oxford University Press, USA, 2000.
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Kozier, Wilkinson. Fundamentals of Nursing with Nursing Process in Action Bundle. Benjamin-Cummings Publishing Company, 1999.
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Hegner, Barbara, e Barbara Acello. Bundle : Nursing Assistant: A Nursing Process Approach, 11th + Workbook. Delmar Cengage Learning, 2015.
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Corey, Gerald, Cindy Corey e Marianne Schneider Corey. Bundle : Groups: Process and Practice, 9th + Group Techniques, 4th. Brooks/Cole, 2014.
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Facts101, Just the. Exam Prep for Bundle; Nursing Assistant; A Nursing Process ... Content Technologies, Inc., 2019.
Encontre o texto completo da fonteCapítulos de livros sobre o assunto "Procesi bundles"
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Losev, Ivan. "Procesi Bundles and Symplectic Reflection Algebras". In Algebraic and Analytic Microlocal Analysis, 3–61. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-01588-6_1.
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Guo, Rongjiao, e Renjun Yan. "Prediction of Mechanical Properties and Analysis of Damage Evolution of Fiber Bundles in Carbon Fiber Reinforced Composite Materials". In Lecture Notes in Mechanical Engineering, 633–46. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-1876-4_50.
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AbstractFiber bundles are an important component of woven composite materials, and predicting the mechanical properties of fiber bundles can provide a basis for the study of the mechanical properties of woven composite materials. This paper establishes the micro representative volume element (RVE) model of composite materials, and obtains the equivalent elastic constant of yarn through the model homogenization theory and periodic boundary conditions. Strength prediction is performed through the VUMAT user subroutine of ABAQUS. This paper uses the maximum stress standards and Von Mises standards to predict the damage initiation of TC33 carbon fiber and epoxy resin matrix, respectively. Combined with the constant degradation method, the simulation of the damage behaviors of the micro model is achieved, and the equivalent strength of the fiber bundle is obtained. The effectiveness and correctness of this method are verified by comparing the numerical model results with the Chamis theoretical model results. The accurate prediction of mechanical properties and damage process of fiber bundles provides theoretical support for the analysis of mechanical properties of composites, and has guiding significance for the performance design of composite materials.
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Jakee, Keith, e Stephen M. Jones-Young. "Entrepreneurship as Complex, Bundled Decisions: An Inframarginal Analysis". In Entrepreneurship and the Market Process, 27–65. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-42408-4_3.
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Burger, Lilli, Vanessa Dörlich, Michael Burger, Joachim Linn e Fabio Schneider. "Estimation of Cable Bundle Stiffness Based on Gaussian Process Regression". In Mathematics in Industry, 329–35. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-11818-0_43.
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Khrennikov, Andrei. "A Model of the Process of Thinking Based on the Dynamics of Bundles of Branches and Sets of Bundles of p-ADIC Trees". In Jean Leray ’99 Conference Proceedings, 451–67. Dordrecht: Springer Netherlands, 2003. http://dx.doi.org/10.1007/978-94-017-2008-3_30.
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Kumar, Jainender, Manoj Kumar Majumder, Brajesh Kumar Kaushik e Sudeb Dasgupta. "Analysis of Crosstalk Deviation for Bundled MWCNT with Process Induced Height and Width Variations". In Communications in Computer and Information Science, 214–22. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-42024-5_26.
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Applebaum, David. "A horizontal levy process on the bundle of orthonormal frames over a complete Reimannian manifold". In Lecture Notes in Mathematics, 166–80. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/bfb0094209.
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Slabakova, Roumyana. "A shared linguistic system of multilingual representations". In Studies in Bilingualism, 29–48. Amsterdam: John Benjamins Publishing Company, 2023. http://dx.doi.org/10.1075/sibil.65.02sla.
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This chapter discusses multilingual and probes the question of whether they form a shared linguistic system. Recent psycholinguistic and studies of multilingual individuals suggest that this is indeed the case. Taking Minimalist morphosyntax and Lardiere’s (2009) feature reassembly as starting points, we consider whether a can be updated and re-assembled as a complete unit in the third language, or whether it has to be broken down into separate which are updated separately. The latter option makes sure that features from both known languages, if they are acquired to a functional level, can exert (CLI). Restructuring each feature bundle depends not just on the availability of facilitation, but on other properties of the which affect what becomes in the additional grammar. Both experiential factors (such as dominance and proficiency) and linguistic factors (such as frequency in the input and complexity) can and do affect the acquisition process.
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Schaefer, Teresa, Barbara Kieslinger, Miriam Brandt e Vanessa van den Bogaert. "Evaluation in Citizen Science: The Art of Tracing a Moving Target". In The Science of Citizen Science, 495–514. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-58278-4_25.
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AbstractEvaluation is a core management instrument and part of many scientific projects. Evaluation can be approached from several different angles, with distinct objectives in mind. In any project, we can evaluate the project process and the scientific outcomes, but with citizen science this does not go far enough. We need to additionally evaluate the effects of projects on the participants themselves and on society at large. While citizen science itself is still in evolution, we should aim to capture and understand the multiple traces it leaves in its direct and broader environment. Considering that projects often have limited resources for evaluation, we need to bundle existing knowledge and experiences on how to best assess citizen science initiatives and continually learn from this assessment. What should we concentrate on when we evaluate citizen science projects and programmes? What are current practices and what are we lacking? Are we really targeting the most relevant aspects of citizen science with our current evaluation approaches?
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(Mary) Tai, Hsueh-Yung, Yu-Pin Chang e Shwu-Huey Wu. "High-Value Medical Information and Quality Claims Review". In Digital Health Care in Taiwan, 189–205. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05160-9_10.
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AbstractThe big data generated by the National Health Insurance (NHI) medical information system is the most important asset that Taiwan possesses in promoting national digital policies. Hence, it is the NHI’s priority to maintain the quality of the dataset and its interoperability with healthcare facilities. This chapter presents the process for claiming medical expenses in detail and gives examples of how the National Health Insurance Administration (NHIA) proactively assists providers to submit accurate claims.Although most medical examination and test results, images, etc., are uploaded in a timely manner to the NHI medical information system, the NHIA plans to bundle the reimbursement to the provider with data upload to further its accuracy. The author explains the strategies applied to strengthen the connection between the hospital information system of contracted institutions and the National Health Insurance MediCloud System (NHI MediCloud System) to improve the accuracy of the data uploaded, such as medical visit identifier, instant upload, and the write-off mechanism.The long-term collaboration among the NHI, contracted institutions, and information system vendors is the key to guaranteeing the quality of the dataset.
Trabalhos de conferências sobre o assunto "Procesi bundles"
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BARLOW, GEORGE, MATHEW SCHEY e SCOTT STAPLETON. "ACHIEVING REALISTIC TOW FIBER VOLUME FRACTIONS IN TEXTILE COMPOSITE MODELS BY INDUCING FIBER ENTANGLEMENT". In Thirty-sixth Technical Conference. Destech Publications, Inc., 2021. http://dx.doi.org/10.12783/asc36/35945.
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Modeling composites can be an effective way to understand how a part will perform without requiring the destruction of costly specimens. By combining artificial fiber entanglement with manufacturing process simulation, a method was developed to create fiber bundle models using entanglement to control the fiber volume fraction. This fiber entanglement generation uses three parameters, probability of swapping (p_(r_S )), swapping radius standard deviation (r_(σ_S )), and the swapping plane spacing (l_S), to control the amount of entanglement within the fiber bundle. A parametric study was conducted and found that the more entanglement within a fiber bundle, the more compression mold pressure required to compact the fiber bundle to the same fiber volume fraction as that required for a less entangled bundle. This artificial fiber entanglement and manufacturing process simulation method for creating fiber bundles shows the potential to be able to create bundles with controlled final volume fraction using a desired mold compression pressure.
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Malik, M. Afzaal, Badar Rashid e Shahab Khushnood. "A Comparative Study of Cross-Flow Induced Vibrations in Heat Exchanger Tube Bundles Using Bond Graph Approach". In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-80469.
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Flow-induced vibration (FIV) has been a major concern in the nuclear and process industries involving steam generator and heat exchanger tube bundle design. Various techniques and models have been developed and used for the analysis of cross-flow induced vibration of tube bundles. Bond Graph approach has been applied to existing FIV excitation models, followed by a comparative study. Results have been obtained using 20-SIM software. It is expected that the current approach will give a new dimension to the FIV analysis of tube bundles.
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LIM, HYOUNG JUN, HO-IL CHOI e GUN JIN YUN. "MICRO-CT IMAGE-BASED RECONSTRUCTION MODEL FOR FAILURE ANALYSIS OF SHEET MOLDING COMPOUND (SMC) COMPOSITES". In Thirty-sixth Technical Conference. Destech Publications, Inc., 2021. http://dx.doi.org/10.12783/asc36/35910.
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This research provides a multiscale framework of failure analysis for carbon-fiber sheet molding compound (CF-SMC) through a bundle packing reconstruction algorithm and material constitutive modeling, respectively. SMC composites have attracted the attention of many industries due to their high strength-to-weight ratio. However, depending on the speed and pressure in the manufacturing process, the spatially different flow patterns of fiber bundles lead to show inhomogeneous mechanical performance. This is because the location and orientation of fiber bundles in SMC composites have a significant role in mechanical behavior. Therefore, it is crucial to understand the effects of these parameters on mechanical behavior. Therefore, in this study, micro-CT imaging is performed to accurately determine SMC composites' internal geometry. The orientation and location of fiber bundles are statistically expressed as cumulative distribution function (CDF). Using these distributions as input, a mesoscale representative volume element (RVE) is constructed through a bundle packing reconstruction algorithm based on the random sequential adsorption (RSA) method. Furthermore, to demonstrate failure analysis of the SMC composites, constitutive modeling of each constituent is established. Consequently, the change of mechanical behavior is estimated under different manufacturing conditions.
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Stevanovic, Vladimir, Zoran Stosic e Uwe Stoll. "Analytical and CFD Investigation of Ex-Core Cooling of the Nuclear Fuel Rod Bundle in a Water Pool". In 12th International Conference on Nuclear Engineering. ASMEDC, 2004. http://dx.doi.org/10.1115/icone12-49530.
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The efficiency of ex-core cooling of nuclear fuel assemblies under decay heat generation is influenced by many conditions, among them being coolant flow rate, position of fuel assemblies in a water pool, and position of coolant inlets and outlets. Although the decay heat generation is lower than the nominal heat power of fuel bundles in operation, the much lower coolant flow rates and coolant inlets and outlets positions can lead to incidents conditions, with a violation of the fuel assembly integrity. Such a combination of unacceptable thermal-hydraulic conditions occurred at the Nuclear Power Plant Paks in Hungary in April 2003, during the process of nuclear fuel assembly chemical cleaning in a specially designed tank. The cooling of the nuclear fuel rod bundles in the tank was not efficient under low coolant flow rates through the cleaning tank, and after several hours the boiling of cooling water occurred with subsequent dry-out of nuclear fuel rod bundles. The thermal-hydraulic conditions in the cleaning tank that led to the unexpected event are analysed both analytically and with a CFD approach for idealised conditions of one nuclear fuel rod bundle with the bottom by-pass opening. The analytical analysis is based on a pressure balance of low Reynolds number upward water coolant flow through the bundle, downward water flow in the pool around the bundle, flow across the by-pass opening and outlet flow from the cleaning vessel. The transient CFD simulations are performed in order to demonstrate multidimensional effects of the event. The water density dependence on the temperature is taken into account in both analytical and CFD investigation, as the dominant effect that influences the buoyancy forces between the water flow streams inside and outside the vertically positioned bundle in the water pool. The influence of the bundle bottom by-pass area on the water pool thermal-hydraulic conditions and on the efficiency of the nuclear fuel rods cooling is analysed. Both analytical and CFD results show that the continuous cooling of the fuel rods can not be achieved for higher values of the bundle bottom by-pass areas. The averaged coolant temperature in the water pool outside the bundle becomes higher than the average temperature along the rod bundle, providing a “negative” buoyancy force that tends to stop the upward coolant flow through the bundle, and, hence, increases the coolant flow through the bundle by-pass at the bottom. The critical value of the by-pass area, above which the rod bundle cooling is deteriorated, is predicted.
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Yim, Seong-Hyuk, e Soo-Hong Lee. "A Development of Wire Path Searching Module Using Extended RCA Method". In ASME 1996 Design Engineering Technical Conferences and Computers in Engineering Conference. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/96-detc/dac-1072.
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Abstract This study deals with a development of wire path searching module as a part of automotive wire harness design system. Wire path searching module manages the free space, finds transition locations, and creates bundle paths to dramatically reduce a tedious iterative routing process which results in easy optimization of the bundle paths. A prime policy in the system configuration is to compromise between man’s and computer’s ability, and make it possible a designer’s leading role in designing process. Human input is indispensable to cope with the special cases which were not considered in the initial design stage of the system. In this study, we improve the previous shortest-path-finding algorithm (VGraph and RCA method) into a new method called Extended RCA. Bundles, connectors and transitions are handled as objects so one can manage and modify physical properties of the objects easily. Therefore a verification is allowed at any desired stage of design. The reuse of previous result is facilitated by using Dependency Structure, which represents the mutual relations among connectors, transitions, and bundles. Dependency Structure makes it possible the elimination of redundant calculating process, and consequently shorter routing time.
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Khushnood, Shahab, Zaffar M. Khan, M. Afzaal Malik, Zafar Ullah Koreshi e Mehmood Anwer Khan. "Vibration Analysis of a Multispan Tube in a Bundle". In 10th International Conference on Nuclear Engineering. ASMEDC, 2002. http://dx.doi.org/10.1115/icone10-22210.
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Nuclear and process industry has seen tube bundle failures more frequently in recent years. There is some concern that the practice of structural configuration has not advanced as rapidly as thermal design of heat exchangers. Catastrophic vibration of tube in a bundle can be avoided if the tube natural frequency is kept well above the estimated existing turbulent buffeting frequencies. Flow distribution and partial admission in to the tube bundle due to upstream piping further complicates the system. In this paper, tube in a bundle has been modeled as a beam on multiple supports. Effects of damping and motion of boundaries have also been considered. Governing equations have been solved analytically for natural as well as forced vibrations. The model has been extended for a bundle of tubes by developing and implementing a computer code. Subsequent experimental verification of results on a research heat exchanger bundle has been carried. The proposed model is expected to prove a useful guide in predicting the vibration behavior of tube bundles.
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Kirsch, Susanne-Marie, Felix Welsch, Lukas Ehl, Franziska Louia, Stefan Seelecke e Paul Motzki. "Systematic Thermo-Mechanical Validation of Numerous Tensile-Loaded NiTi Wire Bundles Used for Elastocaloric Heating and Cooling". In ASME 2023 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2023. http://dx.doi.org/10.1115/smasis2023-110889.
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Abstract Nickel-Titanium (NiTi)-based shape memory alloys (SMAs) enable new sustainable and environmentally friendly solid-state heating and cooling technologies. Elastocaloric (EC) heat pump systems exploit superelastic SMAs as a non-volatile, inflammable, and non-global-warming refrigerant, in contrast to the well-established vapor compression technology. The high specific latent heat released or absorbed during mechanical loading or unloading of the SMA material leads to a high temperature change in the material. As a result of the small required work input to induce the phase transformation, a high coefficient of performance (COP) can be achieved by this technology. The potential of these alloys can be exploited through an adequate thermodynamic cycle, efficient mechanical system design, and choice of suited EC materials. A fully functional continuous operating EC heat pump system based on SMA was developed and realized recently. The EC heat pump system comprises 24 thin wire bundles of 30 wire segments in one bundle. To assist the design process of an optimized device with given performance and efficiency requirements, the air-cooling behavior of single wires and simple bundle arrangement has been analyzed, and intensive parameter studies on different airflow rates have been performed. Regarding validating the EC heat pump system, a reproducible manufacturing process is presented for the first time, which supports the installation of at least 720 SMA segments in the same thermo-mechanical state. This work introduces the bundle fabrication process for the first time and validates it by comparing the key thermo-mechanical values of 135 SMA bundles.
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Khushnood, Shahab, Zaffar M. Khan, M. Afzaal Malik, Zafarullah Koreshi e Mahmood Anwar Khan. "Modeling and Simulation of Cross-Flow Induced Vibration in a Multi-Span Tube Bundle". In 12th International Conference on Nuclear Engineering. ASMEDC, 2004. http://dx.doi.org/10.1115/icone12-49161.
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Flow-induced vibration in steam generator and heat exchanger tube bundles has been a source of major concern in nuclear and process industry. Tubes in a bundle are the most flexible components of the assembly. Flow induced vibration mechanisms, like fluid-elastic instability, vortex shedding, turbulence induced excitation and acoustic resonance results in failure due to mechanical wear, fretting and fatigue cracking. The general trend in heat exchanger design is towards larger exchangers with increased shell side velocities. Costly plant shutdowns have been the motivation for research in the area of cross-flow induced vibration in steam generators and process exchangers. The current paper focuses on the development of a computer code (FIVPAK) for the design (natural frequencies, variable geometry, tube pitch & pattern, mass damping parameter, reduced velocity, strouhal and damage numbers, added mass, wear work rates, void fraction for two-phase, turbulence and acoustic considerations etc.) of tube bundles with respect to cross flow-induced vibration. The code has been validated against Tubular Exchanger Manufacturers (TEMA), Flow-Induced Vibration code (FIV), and results on an actual variable geometry exchanger, specially manufactured to simulate real systems. The proposed code is expected to prove a useful tool in designing a tube bundle and to evaluate the performance of an existing system.
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Tan, Huade, e Y. Lawrence Yao. "Laser Joining of Continuous Glass Fiber Composite Pre-Forms". In ASME 2012 International Manufacturing Science and Engineering Conference collocated with the 40th North American Manufacturing Research Conference and in participation with the International Conference on Tribology Materials and Processing. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/msec2012-7304.
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A laser fusion joining method is investigated for the purpose of through thickness strengthening of fiber pre-forms used in the vacuum infusion fabrication of thick composite structures. Laser joining is achieved without filler materials to replace adhesives, pins or stitches used in conventional composite fabrication. A two step joining process is developed to fuse fibers within a single bundle and between multiple fiber bundles. Finite element analysis is used to investigate the joint strength with respect to joint morphology. Joint strength is found to be a function of the fiber contact angle and packing density at the joint interface. Tensile tests show that laser joined fiber bundles exhibit higher strength than comparable fastening methods. Lessons learned from the axial joining of fiber bundles are applied to joining in the radial and thickness directions of 3d pre-form architectures. Flow induced joint morphology and densification effects observed in the axial direction indicate the need for a two step joining process in the thickness direction. Fiber compaction effects on joint strength in the axial direction motivate the need for high fiber packing fraction at joint interfaces in the thickness direction.
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Chen, Ya-Ping, Chen-Jie Shi, Ming-Heng Shi e Chen-Min Ling. "Numerical Simulation of Heat and Mass Transfer Enhancement in Absorption Process With Double-Side Film-Inversion". In ASME 2008 6th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2008. http://dx.doi.org/10.1115/icnmm2008-62259.
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Film-inversion is an effective way recently developed to enhance heat and mass transfer in absorbers. However, only one-side of round or rectangular tube i.e. half of the total heat transfer area is used to form film-inverting configuration in the published literature. The paper presents a double-side film-inverting scheme, which consists of two plate bundles and a set of comb shaped conjunction guiders between them for leading solution film from both-sides of each couple of the upper plate bundle to the opposite sides of the bottom ones. A two-scale crosswise corrugation plate bundle, which has vertical large corrugations and horizontal small ones, is suggested instead of the plane plate bundle. The horizontal small corrugation can make the film turbulent and film distribution uniform before and after inversion with surface tension effect, thus increasing the heat and mass transfer coefficients of the absorption process. A mathematic model for heat and mass transfer in absorption process with aqueous Li-Br solution falling film-inverting on two sequential vertical plane plates was established and solved numerically. The distributions of dimensionless velocity, temperature and concentration of liquid film profile before and after film-inverting were obtained. The influence of the number of inversion on heat and mass transfer characteristics was analyzed. The calculation results show that the heat and mass transfer coefficients of the once-film-inverting scheme have about 58% and 73% increment respectively over these of the none film-inverting scheme.
Relatórios de organizações sobre o assunto "Procesi bundles"
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Bubenik, Tom, Cara Macrory e Tara McMahan. PR727-223805-Z01 Guidelines for When to Perform Crack Detection In-Line Inspection. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), setembro de 2024. http://dx.doi.org/10.55274/r0000085.
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The goal of this project was to develop flow charted decision processes for operators to determine when ILI is appropriate and recommended. Two initial tasks developed the background material needed for developing the decision processes. Task 1 is a review of publicly available and industry research reports pertaining to the linkage between susceptibility to crack-related failure and performing ILI. Primary references are the results from industry work that informed the development of TTO5 and the development of other industry guidance documents. Task 2 is a survey of operators to understand the extent to which TTO5 does or does not address their integrity management needs regarding reassessments for cracks, and to learn the details of their solutions to perceived shortcomings with TTO5. Task 3 is the development of an updated decision process for determining susceptibility to cracking and the necessary intervals for assessment of the pipeline condition with respect to fatigue cracking and stress-corrosion cracking. Separate decision processes were developed for cracks that grow by fatigue and corrosion (either stress corrosion or corrosion fatigue). The decision process for fatigue crack growth susceptibility and the associated assessment schedule has three frameworks. The process for stress corrosion crack and corrosion fatigue has one. This Bundle includes the Final Report (PR727-223805-R01 Guidelines for When to Perform Crack Detection In-Line Inspection) and 2 White Papers (PR727-223805-R02 Decision Process for Fatigue Crack Growth Susceptibility and Assess White Paper and PR727-223805-R03 Stress Corrosion Cracking Susceptibility White Paper)
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Gillen, Emily, Nicole M. Coomer, Christopher Beadles e Amy Mills. Constructing a Measure of Anesthesia Intensity Using Cross-Sectional Claims Data. RTI Press, outubro de 2019. http://dx.doi.org/10.3768/rtipress.2019.mr.0040.1910.
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With intensifying emphasis on episodes of care and bundled payments for surgical admissions, anesthesia expenditures are increasingly important in assessing variation in expenditures for surgical episodes. When comparing anesthesia expenditures across surgical settings, adjustment for anesthesia case complexity and duration of anesthesia services, also known as anesthesia service intensity, is desirable. A single anesthesia intensity measure allows researchers to make more direct comparisons between anesthesia outcomes across settings and services. We describe a process for creating a claims-based anesthesia intensity measure using Medicare claims. We create the measure using two fields: base units associated with American Medical Association Current Procedural Terminology codes on the anesthesia claim and time units associated with the service. We rescaled the time component of the anesthesia intensity measure to equally represent base units and time units. For illustration, we applied the measure to Medicare anesthesia expenditures stratified by rural/urban location. We found that adjustments for intensity were greater in urban settings because the level of intensity is greater. Compared with rural settings, unadjusted expenditures in urban settings are roughly 26 percent higher, whereas adjusted expenditures in urban settings are only 20 percent higher. Even absent longitudinal data, researchers can adjust anesthesia outcomes for intensity using our cross-sectional claims-based intensity method.
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Cherian, Jerald, Jodi Segal, Ritu Sharma, Allen Zhang, Eric Bass e Michael Rosen. Patient Safety Practices Focused on Sepsis Prediction and Recognition. Agency for Healthcare Research and Quality (AHRQ), abril de 2024. http://dx.doi.org/10.23970/ahrqepc_mhs4sepsis.
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Objectives. Patient safety practices (PSPs) focused on sepsis prediction and recognition, encompass interventions designed to identify patients with sepsis early and improve timely adherence to guidelines. Our objectives were to review the evidence published after the previous Making Healthcare Safer (MHS) report to determine the effectiveness of sepsis prediction and recognition PSPs on patient safety related outcomes. Methods. We searched PubMed and the Cochrane library for systematic reviews and primary studies published from January 2018 through August 2023, supplemented by gray literature searches. We included reviews and primary studies of sepsis prediction and recognition PSPs reporting measures of clinical process (time to diagnosis or treatment, adherence to guidelines, Severe Sepsis and Septic Shock Early Management Bundle), patient outcomes (hospital or intensive care unit (ICU) length of stay, mortality), implementation (use, barriers, and facilitators), or costs. Findings. We focused on 7 systematic reviews and 8 primary studies that were eligible for full review, and briefly summarized 36 pre-post studies that lacked a separate comparison group. All the sepsis prediction and recognition PSPs were multi-component interventions. Across the systematic reviews and primary studies of neonates, the PSPs improved clinical process measures (low strength of evidence), but evidence was insufficient about length of stay or mortality outcomes. Across the systematic reviews and primary studies of adults, the PSPs did not demonstrate an effect on clinical process, length of stay, or mortality outcomes. In primary studies of adults, evidence was insufficient in the prehospital setting for mortality, length of stay, and clinical process measures. In the emergency department setting, strength of evidence was low for mortality and clinical process measures and insufficient for length of stay. In ward or hospitalwide settings, strength of evidence was low across all three outcome types. The secondary outcome of alerting system performance (e.g., positive predictive value) could not be meaningfully compared across studies due to diversity in populations and interventions. Conclusions. This review finds that recent primary studies and systematic reviews do not support that specific PSPs for sepsis prediction and recognition are effective at reducing mortality or length of stay or improve clinical processes in adults in pre-hospital, emergency department, or hospitalwide settings as compared to usual care. Sepsis prediction and recognition PSPs may improve clinical process outcomes in neonates in ICUs.
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Simelton, Elisabeth, Rachmat Mulia, Clement Rigal, Tuan Minh Duong, Phuong Mai Nguyen, Hanna North e Xuan Hieu Le. Beyond carbon sequestration – local knowledge about tree functions. Case study from male and female Arabica coffee farmers in Vietnam. World Agroforestry, 2021. http://dx.doi.org/10.5716/wp21025.pdf.
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Estimates of carbon sequestration for timber trees is well documented, while fruit trees are understudied. The few existing estimates indicate that fruit trees and fertiliser management on them, can substantially sequester carbon in coffee monocultures, albeit unlikely to the same extent as timber trees. A carbon investor may thus favour timber. In this light, as programs for planting billions and trillion trees are launched “to save the climate”, a wide range of gender, social, justice and environmental concerns are voiced. To challenge the mitigation perspective, we contrasted two hypothetical tree planting strategies: a mitigation (carbon finance) perspective and a livelihoods-centred (local) perspective and explored what a rapid, gender and social inclusion-oriented livelihoods perspective could bring to the process of tree selection. The survey documents indigenous knowledge of trees’ potential (dis)benefits in coffee agroforestry systems among 106 female and male arabica-growers in northwest Vietnam. The results display many similarities between women and men in term of perceived benefits from trees. Women and men prioritized trees based on their economic benefits, impacts on coffee production and improved soil fertility. However, in determining the preferred species, women considered more factors, including consequences for pest and disease (on host tree or coffee), microclimate regulation and shade provision. These findings resemble those by others from the same region and demonstrate that consulting both women and men can result in a more diverse shortlist of potential trees for agroforestry/afforestation that reflect both genders’ economic and labour contributions to the household. Furthermore, tree planting projects would benefit from seeking collaboration for bundled ecosystem services, rather than merely from carbon finance. Conversely, carbon investors can rely on farmers’ preferences and rest assured that they also contribute to sequestering carbon.
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Barg, Rivka, Erich Grotewold e Yechiam Salts. Regulation of Tomato Fruit Development by Interacting MYB Proteins. United States Department of Agriculture, janeiro de 2012. http://dx.doi.org/10.32747/2012.7592647.bard.
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Background to the topic: Early tomato fruit development is executed via extensive cell divisions followed by cell expansion concomitantly with endoreduplication. The signals involved in activating the different modes of growth during fruit development are still inadequately understood. Addressing this developmental process, we identified SlFSM1 as a gene expressed specifically during the cell-division dependent stages of fruit development. SlFSM1 is the founder of a class of small plant specific proteins containing a divergent SANT/MYB domain (Barg et al 2005). Before initiating this project, we found that low ectopic over-expression (OEX) of SlFSM1 leads to a significant decrease in the final size of the cells in mature leaves and fruits, and the outer pericarp is substantially narrower, suggesting a role in determining cell size and shape. We also found the interacting partners of the Arabidopsis homologs of FSM1 (two, belonging to the same family), and cloned their tomato single homolog, which we named SlFSB1 (Fruit SANT/MYB–Binding1). SlFSB1 is a novel plant specific single MYB-like protein, which function was unknown. The present project aimed at elucidating the function and mode of action of these two single MYB proteins in regulating tomato fruit development. The specific objectives were: 1. Functional analysis of SlFSM1 and its interacting protein SlFSB1 in relation to fruit development. 2. Identification of the SlFSM1 and/or SlFSB1 cellular targets. The plan of work included: 1) Detailed phenotypic, histological and cellular analyses of plants ectopically expressing FSM1, and plants either ectopically over-expressing or silenced for FSB1. 2) Extensive SELEX analysis, which did not reveal any specific DNA target of SlFSM1 binding, hence the originally offered ChIP analysis was omitted. 3) Genome-wide transcriptional impact of gain- and loss- of SlFSM1 and SlFSB1 function by Affymetrix microarray analyses. This part is still in progress and therefore results are not reported, 4) Search for additional candidate partners of SlFSB1 revealed SlMYBI to be an alternative partner of FSB1, and 5) Study of the physical basis of the interaction between SlFSM1 and SlFSB1 and between FSB1 and MYBI. Major conclusions, solutions, achievements: We established that FSM1 negatively affects cell expansion, particularly of those cells with the highest potential to expand, such as the ones residing inner to the vascular bundles in the fruit pericarp. On the other hand, FSB1 which is expressed throughout fruit development acts as a positive regulator of cell expansion. It was also established that besides interacting with FSM1, FSB1 interacts also with the transcription factor MYBI, and that the formation of the FSB1-MYBI complex is competed by FSM1, which recognizes in FSB1 the same region as MYBI does. Based on these findings a model was developed explaining the role of this novel network of the three different MYB containing proteins FSM1/FSB1/MYBI in the control of tomato cell expansion, particularly during fruit development. In short, during early stages of fruit development (Phase II), the formation of the FSM1-FSB1 complex serves to restrict the expansion of the cells with the greatest expansion potential, those non-dividing cells residing in the inner mesocarp layers of the pericarp. Alternatively, during growth phase III, after transcription of FSM1 sharply declines, FSB1, possibly through complexing with the transcription factor MYBI serves as a positive regulator of the differential cell expansion which drives fruit enlargement during this phase. Additionally, a novel mechanism was revealed by which competing MYB-MYB interactions could participate in the control of gene expression. Implications, both scientific and agricultural: The demonstrated role of the FSM1/FSB1/MYBI complex in controlling differential cell growth in the developing tomato fruit highlights potential exploitations of these genes for improving fruit quality characteristics. Modulation of expression of these genes or their paralogs in other organs could serve to modify leaf and canopy architecture in various crops.