Artigos de revistas: "Pompes à vis"

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Dolgova, Т. А. "TITUS LABIENUS, VIR «FORTIS IN ARMIS»". Ancient World and Archaeology 21, n.º 21 (2023): 207–24. http://dx.doi.org/10.18500/0320-961x-2023-21-207-224.

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the article examines the activities of Titus Labienus, Caesar’s legate in Gaul and a prominent commander in Pompey’s army during the Civil War. His biography is known with large lacunas, as are his political leanings. In Caesar’s Gallic campaigns Labienus served as a legatus pro praetore and proved himself to be a talented military commander. But the fact that he had been praetor before this seems doubtful. With the outbreak of the civil war Labienus defected to Pompey. The motive seems to have been his unsatisfied ambition. After Pompey’s death, Labienus took part in the fight against Caesar in Africa and Spain. Changing sides, Labienus left himself no choice but to fight to the end.

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Pelizzari, Maria Antonella. "Pompeo Bondini:Della Via Appia(1853)". History of Photography 20, n.º 1 (março de 1996): 12–23. http://dx.doi.org/10.1080/03087298.1996.10443604.

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Callarisa Mas, Joan, e Margarita Guinó Arias. "Reporteros de la historia: la gamificación en el marco de un proyecto interdisciplinar en un aula multigrado de primaria". Clío, n.º 48 (30 de dezembro de 2022): 160–81. http://dx.doi.org/10.26754/ojs_clio/clio.2022487223.

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Este artículo describe el desarrollo de un proyecto colaborativo compartido entre escuela y universidad. En este caso, entre la Universidad de Vic y la escuela Pompeu Fabra de Salt. En este proyecto los protagonistas de la experiencia son los alumnos del tercer ciclo de primaria de la escuela Pompeu Fabra de Salt (Gironès) y el grupo de trece alumnos de la Universidad de Vic matriculados en la asignatura Didáctica de las Ciencias Sociales, del doble grado en Maestro de Educación Infantil y Primaria en mención inglesa. Esta colaboración se ha vertebrado en torno a la participación del grupo de primaria en el proyecto interdisciplinar "Reporteros de la historia”.

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Varakantham, Pradeep, Jun-young Kwak, Matthew Taylor, Janusz Marecki, Paul Scerri e Milind Tambe. "Exploiting Coordination Locales in Distributed POMDPs via Social Model Shaping". Proceedings of the International Conference on Automated Planning and Scheduling 19 (16 de outubro de 2009): 313–20. http://dx.doi.org/10.1609/icaps.v19i1.13369.

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Distributed POMDPs provide an expressive framework for modeling multiagent collaboration problems, but NEXP-Complete complexity hinders their scalability and application in real-world domains. This paper introduces a subclass of distributed POMDPs, and TREMOR, an algorithm to solve such distributed POMDPs. The primary novelty of TREMOR is that agents plan individually with a single agent POMDP solver and use social model shaping to implicitly coordinate with other agents. Experiments demonstrate that TREMOR can provide solutions orders of magnitude faster than existing algorithms while achieving comparable, or even superior, solution quality.

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Do, Hung, Naresh K. Meena e Nina Raben. "Failure of Autophagy in Pompe Disease". Biomolecules 14, n.º 5 (13 de maio de 2024): 573. http://dx.doi.org/10.3390/biom14050573.

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Autophagy is an evolutionarily conserved lysosome-dependent degradation of cytoplasmic constituents. The system operates as a critical cellular pro-survival mechanism in response to nutrient deprivation and a variety of stress conditions. On top of that, autophagy is involved in maintaining cellular homeostasis through selective elimination of worn-out or damaged proteins and organelles. The autophagic pathway is largely responsible for the delivery of cytosolic glycogen to the lysosome where it is degraded to glucose via acid α-glucosidase. Although the physiological role of lysosomal glycogenolysis is not fully understood, its significance is highlighted by the manifestations of Pompe disease, which is caused by a deficiency of this lysosomal enzyme. Pompe disease is a severe lysosomal glycogen storage disorder that affects skeletal and cardiac muscles most. In this review, we discuss the basics of autophagy and describe its involvement in the pathogenesis of muscle damage in Pompe disease. Finally, we outline how autophagic pathology in the diseased muscles can be used as a tool to fast track the efficacy of therapeutic interventions.

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Smith, Barbara K., David D. Fuller, A. Daniel Martin, Lawrence Lottenberg, Saleem Islam, Lee Ann Lawson, Raymond P. Onders e Barry J. Byrne. "Diaphragm Pacing as a Rehabilitative Tool for Patients With Pompe Disease Who Are Ventilator-Dependent: Case Series". Physical Therapy 96, n.º 5 (1 de maio de 2016): 696–703. http://dx.doi.org/10.2522/ptj.20150122.

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Background and Purpose Pompe disease is an inherited disorder notable for severe, progressive ventilatory compromise. Although ventilatory failure has been attributed to myofiber dysfunction secondary to diaphragmatic glycogen accumulation, neural involvement of the phrenic motor system is also a prominent feature. Direct diaphragm pacing supplements respiratory function in other disorders of the phrenic motor system. Accordingly, it is hypothesized that augmented neuromuscular activity via diaphragm pacing would promote weaning from mechanical ventilation in patients with Pompe disease who are unresponsive to conventional, muscle-directed treatments. Case Description Three patients with Pompe disease developed diaphragm paresis that resulted in chronic mechanical ventilation dependence. After preoperative inspiratory muscle strengthening exercises failed to improve function, fine-wire pacing electrodes were laparoscopically implanted into the diaphragm. Diaphragm conditioning was initiated the first postoperative week and consisted of gradual increases in stimulation parameters, lengthening of stimulation sessions, and ventilator weaning. Ventilation and intramuscular electromyographic activity were recorded periodically during conditioning to quantify diaphragm neuromuscular function. Outcomes During paced breathing without mechanical ventilation, tidal volumes increased, and 2 patients were weaned from daytime ventilator dependence within the first 3 months of pacing, which has been sustained over the long-term. A third patient reduced reliance on daytime ventilation, but weaning was delayed by malacia of the large airways. In all patients, pacing appeared to facilitate spontaneous phrenic motor unit activity during independent breathing without ventilator or pacer support. Discussion The findings are consistent with the view that diaphragm pacing has potential rehabilitative value to reduce reliance on mechanical ventilation in people with Pompe disease, but further study is needed. Diaphragm pacing represents a paradigm shift in the management of respiratory insufficiency for Pompe disease that warrants further controlled examination.

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Bates, Piers Baker. "A portrait of Cardinal Pompeo Colonna, rival and imitator of the papal Caesars". Papers of the British School at Rome 76 (novembro de 2008): 183–99. http://dx.doi.org/10.1017/s0068246200000465.

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Nella Galleria Colonna di Roma si trova un ritratto poco considerato di uno delle figure più significative, e lui stesso a sua volta poco considerato, della storia dei primi venticinque anni del XVI secolo a Roma: il Cardinale Pompeo Colonna. I fini di questo articolo sono due: innanzitutto identificare il reale artista di quel ritratto, precedentemente attribuito a Lorenzo Lotto, ma in questa sede identificato come Sebastiano del Piombo; e, in secondo luogo, restituire al Cardinale Pompeo il giusto grado di importanza in questo momento critico della storia del papato e di Roma. Il tema dell'articolo sarà quindi ampliato al fine di comprendere i percorsi che avrebbero reso possibile l'incontro tra il patrono e l'artista, e dimostrare come queste particolari contatti — qui riferiti come ‘imperiali’ — offrano una nuova via per collegare la carriera di Sebastiano del Piombo a Roma.

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Armstrong, Dustin. "VAL-1221: Treating Pompe disease via enhanced glycogen-targeting". Molecular Genetics and Metabolism 132, n.º 2 (fevereiro de 2021): S16. http://dx.doi.org/10.1016/j.ymgme.2020.12.016.

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Amela Valverde, Luis. "La campaña de Pompeyo en Sicilia (82 a.C.)". Myrtia 35 (12 de novembro de 2020): 225–48. http://dx.doi.org/10.6018/myrtia.454901.

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La campaña de Cn. Pompeyo Magno (cos. I 70 a.C.) en la isla de Sicilia durante el año 82 a.C., en el marco de la Primera Guerra Civil (88-81 a.C.), no es muy conocida. No sólo figura de puntillas en obras sobre el mencionado conflicto, sino que en diversas biografías de este personaje apenas se menciona su estancia. En el presente trabajo queremos presentar las acciones que realizó Pompeyo, tanto de carácter positivo (impartir justicia, establecimiento de lazos clientelares, la via Pompeia ) como negativo (ejecución de M. Valerio Sorano [tr. pl. 82 a.C.] y de Cn. Papirio Carbón [cos. II 82 a.C.], lo que le valió el calificativo de adulescentulus carnifex ). The campaign of Cn. Pompey the Great (cos . I 70 BC) on the island of Sicily during the year 82 B.C., in the framework of the First Civil War (88-81 BC), is not well known. Not only does he figure on tiptoe in works on the aforementioned conflict, but in several biographies of this character his stay is hardly mentioned. In this paper we want to present the actions that Pompey carried out, both positive (to provide justice, establishment of clientties, the via Pompeia ) and negative (execution of M. Valerius Soranus [tr . pl . 82 BC] and Cn. Papirius Carbo [cos. II 82 BC], which earned him the qualification of adulescentulus carnifex ).

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Kowalski, A. M., e A. Plastino. "Relative Entropies and Jensen Divergences in the Classical Limit". Advances in Statistics 2015 (27 de janeiro de 2015): 1–8. http://dx.doi.org/10.1155/2015/581259.

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Metrics and distances in probability spaces have shown to be useful tools for physical purposes. Here we use this idea, with emphasis on Jensen Divergences and relative entropies, to investigate features of the road towards the classical limit. A well-known semiclassical model is used and recourse is made to numerical techniques, via the well-known Bandt and Pompe methodology, to extract probability distributions from the pertinent time-series associated with dynamical data.

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Beier, Suzane L., Ademir C. Rosa, Nilson Oleskovicz, Cláudio R. S. Mattoso e Aury N. Moraes. "Efeitos anestésicos da administração intranasal ou intramuscular de cetamina S+ e midazolam em pomba-rola (Streptotelia sp.)". Pesquisa Veterinária Brasileira 33, n.º 4 (abril de 2013): 517–22. http://dx.doi.org/10.1590/s0100-736x2013000400016.

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A via intranasal é uma boa alternativa por ser indolor e de fácil aplicação em aves. O objetivo deste estudo foi avaliar os efeitos anestésicos da associação de cetamina S+ e midazolam pela via intranasal (IN) em comparação com a via intramuscular (IM) em pombos. Foram utilizados 12 pombos alocados em dois grupos com 15 dias de intervalo, os quais receberam: grupo IM: 20 mg/kg de cetamina S+ associada a 3,5 mg/kg de midazolam pela via intramuscular (musculatura do peito); e grupo IN, mesmo protocolo, porém, pela via intranasal. Os parâmetros avaliados foram: período de latência, tempo de duração em decúbito dorsal, tempo total de anestesia, tempo de recuperação e efeitos adversos. Para a análise estatística, empregou-se o teste de Wilcoxon, com as diferenças consideradas significativas quando P<0,05. O período de latência obtido foi de 30 [30-47,5] e 40 [30-50] segundos para IM e IN, respectivamente. O tempo de duração de decúbito dorsal foi de 59 [53,25-65] e 63 [37-71,25] minutos para IM e IN, respectivamente, sem diferenças significativas entre os grupos. Com relação à duração total de anestesia, foi observada diferença significativa, com 88 [86,25-94,5] e 68 [53,5-93] minutos para os grupos IM e IN, respectivamente. O tempo de recuperação foi mais curto no grupo IN (15 [4,25-19,5]) comparado ao IM (32 [28,25-38,25] minutos). Dois animais de cada grupo apresentaram regurgitação na fase de recuperação. Conclui-se que a administração de cetamina S+ e midazolam pela via intranasal é um método aceitável de administração de fármacos e produz anestesia rápida e eficaz em pombos.

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Sousa, Eliane Pinheiro de, Francisco Diego Guedes Ferreira e Renata Benício de Oliveira. "O PROGRAMA NACIONAL DE ALIMENTAÇÃO ESCOLAR CONTRIBUI PARA A QUALIDADE DE VIDA DOS AGRICULTORES FAMILIARES? UM ESTUDO NAS MESORREGIÕES SERTÕES E NORTE DO CEARÁ". Geo UERJ, n.º 41 (12 de dezembro de 2022): e56880. http://dx.doi.org/10.12957/geouerj.2022.56880.

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Este estudo se propõe mensurar a qualidade de vida dos agricultores familiares que participam do Programa Nacional de Alimentação Escolar (PNAE) vis-à-vis aqueles que não participam, nos Sertões e Norte do estado do Ceará. Para representar tais mesorregiões, foram considerados, respectivamente, os municípios de Senador Pompeu e Ocara, que obtiveram os maiores percentuais de recursos investidos no programa, segundo dados do Fundo Nacional de Desenvolvimento da Educação. A pesquisa foi realizada com 57 produtores rurais, sendo 24 com beneficiários e 33 com não beneficiários do PNAE. Utilizaram-se análise tabular e descritiva e mensurou-se o Índice de Qualidade de Vida (IQV) desses agricultores, considerando os indicadores: Educação; Saúde; Habitação; Condições Sanitárias; Emprego e Renda; Lazer; e Alimentação. Os resultados revelam que, em média, os produtores que fornecem alimentos para a merenda escolar detêm melhores níveis de qualidade de vida do que aqueles que não participam desse programa. Portanto, conclui-se que o PNAE representa um instrumento de bem-estar, já que contribui para melhoria das condições de vida dos agricultores familiares.

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Crettez, Bertrand, e Régis Deloche. "An analytic narrative of Caesar’s death: Suicide or not? That is the question". Rationality and Society 30, n.º 3 (21 de março de 2018): 332–49. http://dx.doi.org/10.1177/1043463118759669.

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On the Ides of March, 44 BC, in the Senate House of Pompey in Rome, Julius Caesar was assassinated by conspirators, the most famous of those being Brutus. Are there objectively valid reasons to confirm the possibility of a suicidal wish on the part of Caesar raised by Suetonius? By building and solving a two-player non-cooperative game that models the historical strategic aspects of the relationship between Caesar and Brutus, our article shows that there is no need to subscribe to the suicide thesis to explain Caesar’s death. We formulate our conclusion via the solution concept of mixed-strategy Nash equilibrium.

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Rezende, Cátia, Eliani Rodrigues Da Silva, Alexandre Henrique Frota Gomes, Renata Camacho Mizziara e João Edson da Silva. "Cryptococcus Neoformans: Primeiro Caso Relatado de Isolamento em Fezes de Pombos no Município de Votuporanga-São Paulo". Revista Brasileira Multidisciplinar 12, n.º 2 (16 de janeiro de 2009): 67. http://dx.doi.org/10.25061/2527-2675/rebram/2009.v12i2.158.

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Cryptococcus neoformans e Cryptococcus gattii são fungos patogênicos causadores de pneumonia e meningite em pacientes imunodebilitados e imunocompetentes. Ambas as espécies são encontradas no meio ambiente e adquiridas via inalação, ocasionando uma infecção pulmonar inicial. Foram avaliadas 48 amostras de ar e 32 amostras de fezes de pombos entre junho e agosto de 2007. A presença de cápsula foi examinada pela microscopia com Tinta Nanquim. As amostras também foram testadas para produção de urease e da enzima fenoloxidase. Cryptococcus neoformans foi isolado em 3,1% de fezes de pombos. Os resultados sugerem que condições climáticas podem afetar a ocorrência da levedura em diferentes fontes ambientais.

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Carlsson, Niklas, Edith Cohen e Philippe Robert. "POMACS V5, N3, December 2021 Editorial". Proceedings of the ACM on Measurement and Analysis of Computing Systems 5, n.º 3 (14 de dezembro de 2021): 1. http://dx.doi.org/10.1145/3491041.

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The ACM Proceedings of the ACM on Measurement and Analysis of Computing Systems (POMACS) focuses on the measurement and performance evaluation of computer systems and operates in close collaboration with the ACM Special Interest Group SIGMETRICS. All papers in this issue of POMACS will be presented during the ACM SIGMETRICS/Performance 2022 conference. The issue contains papers selected by the editorial board via a rigorous review process that follows a hybrid conference and journal model, with reviews conducted by the 93 members of our POMACS editorial board. Each paper was either conditionally accepted (and shepherded), allowed a "one-shot" revision (to be resubmitted to one of the subsequent two deadlines), or rejected (with resubmission allowed after a year). For this issue, which represents the summer deadline, POMACS publishes 17 papers out of 71 submissions. All submitted papers received at least 3 reviews and we held an online TPC meeting. Based on the indicated primary track, roughly 37% of the submissions were in the Theory track, 30% were in the Measurement & Applied Modeling track, 20% were in the Systems track, and 14% were in the Learning track. Many people contributed to the success of this issue of POMACS. First, we would like to thank the authors, who submitted their best work to SIGMETRICS/POMACS. Second, we would like to thank the TPC members who provided constructive feedback in their reviews to authors and participated in the online discussions and TPC meetings. We also thank the several external reviewers who provided their expert opinion on specific submissions that required additional input. We are also grateful to the SIGMETRICS Board Chair, Giuliano Casale, and to past TPC Chairs, Anshul Gandhi, Negar Kiyavash, and Jia Wang, who provided a wealth of information and guidance (including a template for writing this editorial note!). Finally, we are grateful to the Organization Committee and to the SIGMETRICS Board for their ongoing efforts and initiatives for creating an exciting program for ACM SIGMETRICS/Performance 2022.

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Onache, Petronela Anca, Elisabeta-Irina Geana, Corina Teodora Ciucure, Alina Florea, Dorin Ioan Sumedrea, Roxana Elena Ionete e Ovidiu Tița. "Bioactive Phytochemical Composition of Grape Pomace Resulted from Different White and Red Grape Cultivars". Separations 9, n.º 12 (28 de novembro de 2022): 395. http://dx.doi.org/10.3390/separations9120395.

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Grapes are rich in phenolic compounds, being important for human health with anti-inflammatory, antiatherosclerotic, antimutagenic, anticarcinogenic, antibacterial, antiviral, and antimicrobial activity. The winemaking of the grapes generates significant amounts of waste. These wastes contain bioactive compounds in their biomass that can be used as a source of food improvement or as a source of nutrition supplementation. This study looks at the content of bioactive compounds, the polyphenolic profile, and the antioxidant activity in different white and red grape pomaces. The investigation of bioactive characteristics (total polyphenols, total flavonoids, catechins, tannins, and antioxidant activity) was carried out by UV-Vis spectrophotometric methods, while the individual polyphenolic composition was investigated by target and screening UHPLC-HRMS/MS analysis. Principal components (PCA) and the heat maps analysis allows the discrimination between the grape pomace resulted from white grape cultivars (Muscat Ottonel and Tamaioasa Romaneasca) and red grape pomaces (Cabernet Sauvignon, Merlot, Feteasca Neagra, Burgund Mare, Pinot Nore), with the identification of the specific phenolic compounds for each grape pomace type.

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Corrêa, Elisa Cristina Delfini, e Miguel Ángel Marzal García-Quismodo. "Tendências de inovação em serviços de bibliotecas universitárias: estudo de caso do CRAI Universitat Pompeu Fabra em Barcelona, Espanha". Em Questão 27, n.º 1 (22 de dezembro de 2020): 430–55. http://dx.doi.org/10.19132/1808-5245271.430-455.

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Neste artigo, são analisados produtos e serviços de base digital oferecidos pelo Centro de Recursos para Aprendizagem e Investigação da Universitat Pompeu Fabra em Barcelona, Espanha. O perfil da pesquisa é comparativo, bibliográfico e documental, e os dados foram coletados a partir de leitura e análise dos relatórios do New Media Consortium – NMC Horizon Report: 2015 Library Edition e NMC Horizon Report: 2017 Library Edition e da página web do Centro de Recursos para Aprendizagem e Investigação da Universitat Pompeu Fabra. Dados foram coletados também por meio de observação não participante realizada em visita à biblioteca do Campus del Poblenau, o que permite caracterizar a pesquisa como estudo de caso. Os dados foram submetidos a análise de conteúdo e foram categorizados. Os resultados demonstram a presença de muitas das tendências apresentadas nos relatórios do New Media Consortium, em especial aquelas de uso de tecnologia mais básica. É possível também observar, um pouco mais timidamente, a personalização de alguns serviços de acordo com as necessidades dos pesquisadores, assim como a oferta de ferramentas 2.0, bem como a entrega de conteúdos via dispositivos eletrônicos. O uso de tecnologias mais avançadas como Big Data, inteligência artificial ou tecnologia de localização, por exemplo, ainda não é encontrado. Conclui-se que são perceptíveis esforços para uma constante implementação de serviços e produtos de base digital, e, embora avanços tecnológicos mais sofisticados ainda não sejam encontrados, é possível identificar uma aproximação com as tendências apontadas pelos relatórios analisados.

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Simão, Thiago D., Marnix Suilen e Nils Jansen. "Safe Policy Improvement for POMDPs via Finite-State Controllers". Proceedings of the AAAI Conference on Artificial Intelligence 37, n.º 12 (26 de junho de 2023): 15109–17. http://dx.doi.org/10.1609/aaai.v37i12.26763.

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We study safe policy improvement (SPI) for partially observable Markov decision processes (POMDPs). SPI is an offline reinforcement learning (RL) problem that assumes access to (1) historical data about an environment, and (2) the so-called behavior policy that previously generated this data by interacting with the environment. SPI methods neither require access to a model nor the environment itself, and aim to reliably improve upon the behavior policy in an offline manner. Existing methods make the strong assumption that the environment is fully observable. In our novel approach to the SPI problem for POMDPs, we assume that a finite-state controller (FSC) represents the behavior policy and that finite memory is sufficient to derive optimal policies. This assumption allows us to map the POMDP to a finite-state fully observable MDP, the history MDP. We estimate this MDP by combining the historical data and the memory of the FSC, and compute an improved policy using an off-the-shelf SPI algorithm. The underlying SPI method constrains the policy space according to the available data, such that the newly computed policy only differs from the behavior policy when sufficient data is available. We show that this new policy, converted into a new FSC for the (unknown) POMDP, outperforms the behavior policy with high probability. Experimental results on several well-established benchmarks show the applicability of the approach, even in cases where finite memory is not sufficient.

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Carlsson, Niklas, Edith Cohen e Philippe Robert. "POMACS V6, N1, March 2022 Editorial". Proceedings of the ACM on Measurement and Analysis of Computing Systems 6, n.º 1 (24 de fevereiro de 2022): 1. http://dx.doi.org/10.1145/3508021.

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The ACM Proceedings of the ACM on Measurement and Analysis of Computing Systems (POMACS) focuses on the measurement and performance evaluation of computer systems and operates in close collaboration with the ACM Special Interest Group SIGMETRICS. All papers in this issue of POMACS will be presented during the ACM SIGMETRICS/Performance 2022 conference. The issue contains papers selected by the editorial board via a rigorous review process that follows a hybrid conference and journal model, with reviews conducted by the 97 members of our POMACS editorial board. Each paper was either conditionally accepted (and shepherded), allowed a "one-shot" revision (to be resubmitted to one of the subsequent two deadlines), or rejected (with resubmission allowed after a year). For this issue, which represents the fall deadline, we accepted 25 papers out of 106 submissions (including 4 papers that had been given a "one-shot" revision opportunity). All submitted papers received at least 3 reviews and we held an online TPC meeting. Based on the indicated primary track, roughly 30% of the submissions were in the Measurement & Applied Modeling track, 28% were in the Systems track, 26% were in the Theory track, and 15% were in the Learning track. Many people contributed to the success of this issue of POMACS. First, we would like to thank the authors, who submitted their best work to SIGMETRICS/POMACS. Second, we would like to thank the TPC members who provided constructive feedback in their reviews to authors and participated in the online discussions and TPC meetings. We also thank several external reviewers who provided their expert opinion on specific submissions that required additional input. We are also grateful to the SIGMETRICS Board Chair, Giuliano Casale, and to past TPC Chairs. Finally, we are grateful to the Organization Committee and to the SIGMETRICS Board for their ongoing efforts and initiatives for creating an exciting program for ACM SIGMETRICS/Performance 2022.

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Avrachenkov, Konstantin, Phillipa Gill e Bhuvan Urgaonkar. "POMACS V6, N3 December 2022 Editorial". Proceedings of the ACM on Measurement and Analysis of Computing Systems 6, n.º 3 (dezembro de 2022): 1. http://dx.doi.org/10.1145/3570602.

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The Proceedings of the ACM on Measurement and Analysis of Computing Systems (POMACS) focuses on the measurement and performance evaluation of computer systems and operates in close collaboration with the ACM Special Interest Group SIGMETRICS. All papers in this issue of POMACS will be presented at the ACM SIGMETRICS 2023 conference on June 19-13, 2023, in Orlando, Florida, USA. These papers have been selected by the 82 members of the ACM SIGMETRICS 2023 program committee via a rigorous review process. Each paper was conditionally accepted (and shepherded), allowed a "one-shot" revision (to be resubmitted to one of the subsequent three SIGMETRICS deadlines), or rejected (with re-submission allowed after a year). For this issue, which represents the summer deadline, POMACS is publishing 17 papers out of 93 submissions. All submissions received at least 3 reviews and borderline cases were extensively discussed during the online program committee meeting. Based on the indicated track(s), roughly 30% of the submissions were in the Theory track, 39% were in the Measurement Applied Modeling track, 33% were in the Systems track, and 29% were in the Learning track. Many individuals contributed to the success of this issue of POMACS. First, we would like to thank the authors, who submitted their best work to SIGMETRICS/POMACS. Second, we would like to thank the program committee members who provided constructive feedback in their reviews to authors and participated in the online discussions and program committee meeting. We also thank the several external reviewers who provided their expert opinion on specific submissions that required additional input. We are also grateful to the SIGMETRICS Board Chair, Giuliano Casale, and to past program committee Chairs, Niklas Carlsson, Edith Cohen, and Philippe Robert, who provided a wealth of information and guidance. Finally, we are grateful to the Organization Committee and to the SIGMETRICS Board for their ongoing efforts and initiatives for creating an exciting program for ACM SIGMETRICS 2023.

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Avrachenkov, Konstantin, Phillipa Gill e Bhuvan Urgaonkar. "POMACS V7, N1, March 2023 Editorial". Proceedings of the ACM on Measurement and Analysis of Computing Systems 7, n.º 1 (27 de fevereiro de 2023): 1. http://dx.doi.org/10.1145/3579311.

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The Proceedings of the ACM on Measurement and Analysis of Computing Systems (POMACS) focuses on the measurement and performance evaluation of computer systems and operates in close collaboration with the ACM Special Interest Group SIGMETRICS. All papers in this issue of POMACS will be presented at the ACM SIGMETRICS 2023 conference on June 19-23, 2023, in Orlando, Florida, USA. These papers have been selected during the fall submission round by the 91 members of the ACM SIGMETRICS 2023 program committee via a rigorous review process. Each paper was conditionally accepted (and shepherded), allowed a "one-shot" revision (to be resubmitted to one of the subsequent three SIGMETRICS deadlines), or rejected (with re-submission allowed after a year). For this issue, which represents the fall deadline, POMACS is publishing 26 papers out of 119 submissions. All submissions received at least 3 reviews and borderline cases were extensively discussed during the online program committee meeting. Based on the indicated track(s), roughly 21% of the submissions were in the Theory track, 40% were in the Measurement & Applied Modeling track, 29% were in the Systems track, and 39% were in the Learning track. Many individuals contributed to the success of this issue of POMACS. First, we would like to thank the authors, who submitted their best work to SIGMETRICS/POMACS. Second, we would like to thank the program committee members who provided constructive feedback in their reviews to authors and participated in the online discussions and program committee meeting. We also thank the several external reviewers who provided their expert opinion on specific submissions that required additional input. We are also grateful to the SIGMETRICS Board Chair, Giuliano Casale, and to past program committee Chairs, Niklas Carlsson, Edith Cohen, and Philippe Robert, who provided a wealth of information and guidance. Finally, we are grateful to the Organization Committee and to the SIGMETRICS Board for their ongoing efforts and initiatives for creating an exciting program for ACM SIGMETRICS 2023.

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Avrachenkov, Konstantin, Phillipa Gill e Bhuvan Urgaonkar. "POMACS V7, N2, June 2023 Editorial". Proceedings of the ACM on Measurement and Analysis of Computing Systems 7, n.º 2 (19 de maio de 2023): 1–2. http://dx.doi.org/10.1145/3589972.

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The Proceedings of the ACM on Measurement and Analysis of Computing Systems (POMACS) focuses on the measurement and performance evaluation of computer systems and operates in close collaboration with the ACM Special Interest Group SIGMETRICS. All papers in this issue of POMACS will be presented at the ACM SIGMETRICS 2023 conference on June 19-23, 2023, in Orlando, Florida, USA. These papers have been selected during the winter submission round by the 91 members of the ACM SIGMETRICS 2023 program committee via a rigorous review process. Each paper was conditionally accepted (and shepherded), allowed a "one-shot" revision (to be resubmitted to one of the subsequent three SIGMETRICS deadlines), or rejected (with re-submission allowed after a year). For this issue, which represents the winter deadline, POMACS is publishing 11 papers out of 130 submissions. All submissions received at least 3 reviews and borderline cases were extensively discussed during the online program committee meeting. Based on the indicated track(s), roughly 28% of the submissions were in the Theory track, 44% were in the Measurement & Applied Modeling track, 43% were in the Systems track, and 22% were in the Learning track. Many individuals contributed to the success of this issue of POMACS. First, we would like to thank the authors, who submitted their best work to SIGMETRICS/POMACS. Second, we would like to thank the program committee members who provided constructive feedback in their reviews to authors and participated in the online discussions and program committee meeting. We also thank the several external reviewers who provided their expert opinion on specific submissions that required additional input. We are also grateful to the SIGMETRICS Board Chair, Giuliano Casale, and to past program committee Chairs, Niklas Carlsson, Edith Cohen, and Philippe Robert, who provided a wealth of information and guidance. Finally, we are grateful to the Organization Committee and to the SIGMETRICS Board for their ongoing efforts and initiatives for creating an exciting program for ACM SIGMETRICS 2023.

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Cohen, Jennifer L., Ankit Desai, Cindy Li, Erin Huggins, Gabrielle Cooper, Vikas Bhambhani, Katherine Dempsey et al. "Early diagnosis and treatment of infantile-onset Pompe disease via newborn screen". Molecular Genetics and Metabolism 132, n.º 2 (fevereiro de 2021): S26—S27. http://dx.doi.org/10.1016/j.ymgme.2020.12.044.

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Gandhi, Anshul, Negar Kiyavash e Jia Wang. "Editorial". Proceedings of the ACM on Measurement and Analysis of Computing Systems 5, n.º 2 (junho de 2021): 1. http://dx.doi.org/10.1145/3466793.

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The ACM Proceedings of the ACM on Measurement and Analysis of Computing Systems (POMACS) focuses on the measurement and performance evaluation of computer systems and operates in close collaboration with the ACM Special Interest Group SIGMETRICS. All papers in the last three (i.e., this one and the previous two) issues of POMACS will be presented during the ACM SIGMETRICS 2021 virtual conference. Each of the three issues (one per call for papers) contains papers selected by the editorial board via a rigorous review process that follows a hybrid conference and journal model, with reviews conducted by the 86 members of our POMACS editorial board. Each paper was either conditionally accepted (and shepherded), allowed a "one-shot" revision (to be resubmitted to one of the subsequent two deadlines), or rejected (with resubmission allowed after a year). Over the three issues during which we have served as editors, POMACS has published 35 papers out of 315 submissions (84 to the Summer call, 107 to the Fall call, and 124 to the Winter call). All submitted papers received at least 3 reviews and we held an online TPC meeting for each deadline/issue. Based on the indicated primary track, roughly 16% of the submissions were in the Learning track, 29% were in the Measurement & Applied Modeling track, 26% were in the Systems track, and 29% were in the Theory track. Many people contributed to the success of POMACS over the last year. First, we would like to thank the authors, who submitted their best work to SIGMETRICS/POMACS. Second, we would like to thank the TPC members who provided constructive feedback in their reviews to authors and participated in the online discussions and TPC meetings. We also thank the several external reviewers who provided their expert opinion on specific submissions that required additional input. We are also grateful to the SIGMETRICS Board Chair, Giuliano Casale, and to past TPC Chairs, Athina Markopoulou and Y. C. Tay, who provided a wealth of information and guidance. We also thank Adam Wierman for outlining the soft tracking guidelines that were adopted for SIGMETRICS 2021. Finally, we are grateful to the Organization Committee and to the SIGMETRICS Board for their efforts and initiatives in the middle of a pandemic, including making papers and videos available online and enabling online interactions.

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Hauskrecht, M. "Value-Function Approximations for Partially Observable Markov Decision Processes". Journal of Artificial Intelligence Research 13 (1 de agosto de 2000): 33–94. http://dx.doi.org/10.1613/jair.678.

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Partially observable Markov decision processes (POMDPs) provide an elegant mathematical framework for modeling complex decision and planning problems in stochastic domains in which states of the system are observable only indirectly, via a set of imperfect or noisy observations. The modeling advantage of POMDPs, however, comes at a price -- exact methods for solving them are computationally very expensive and thus applicable in practice only to very simple problems. We focus on efficient approximation (heuristic) methods that attempt to alleviate the computational problem and trade off accuracy for speed. We have two objectives here. First, we survey various approximation methods, analyze their properties and relations and provide some new insights into their differences. Second, we present a number of new approximation methods and novel refinements of existing techniques. The theoretical results are supported by experiments on a problem from the agent navigation domain.

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Otrysko, B. E., G. J. Banville e A. Asselin. "Influence du degré de dépendance des tubercules-fils de pommes de terre vis-à-vis de la plante-mère sur leur infestation parRhizoctonia solani". Potato Research 31, n.º 4 (dezembro de 1988): 617–25. http://dx.doi.org/10.1007/bf02361854.

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Cuvillon, P., e C. Boisson. "Contrôler les « pompes d’analgésie » via les nouvelles technologies Internet : simple gadget ou véritable révolution technologique de nos pratiques ?" Annales Françaises d'Anesthésie et de Réanimation 33, n.º 1 (janeiro de 2014): 8–9. http://dx.doi.org/10.1016/j.annfar.2013.12.015.

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Ciucu, Florin, Giulia Fanti e Rhonda Righter. "POMACS V7, N3, December 2023 Editorial". Proceedings of the ACM on Measurement and Analysis of Computing Systems 7, n.º 3 (7 de dezembro de 2023): 1. http://dx.doi.org/10.1145/3626773.

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The Proceedings of the ACM on Measurement and Analysis of Computing Systems (POMACS) focuses on the measurement and performance evaluation of computer systems and operates in close collaboration with the ACM Special Interest Group SIGMETRICS. All papers in this issue of POMACS will be presented at the ACM SIGMETRICS/Performance 2024 conference on June 10-14, 2024, in Venice, Italy. These papers have been selected during the summer submission round by the 84 members of the ACM SIGMETRICS/Performance 2024 program committee via a rigorous review process. Each paper was conditionally accepted (and shepherded), allowed a "one-shot" revision (to be resubmitted to one of the subsequent two SIGMETRICS/Performance deadlines), or rejected (with re-submission allowed after a year). For this issue, which represents the summer deadline, POMACS is publishing 20 papers out of 91 submissions, of which 11 had previously received a one-shot revision decision. All submissions received at least 3 reviews and borderline cases were extensively discussed during the online program committee meeting. Based on the indicated track(s), roughly 27% of the submissions were in the Theory track, 46% were in the Measurement & Applied Modeling track, 41% were in the Systems track, and 14% were in the Learning track. Many individuals contributed to the success of this issue of POMACS. First, we would like to thank the authors, who submitted their best work to SIGMETRICS/Performance/POMACS. Second, we would like to thank the program committee members who provided constructive feedback in their reviews to authors and participated in the online discussions and program committee meeting. We also thank the several external reviewers who provided their expert opinions on specific submissions that required additional input. We are also grateful to the SIGMETRICS Board Chair, Mor Harchol-Balter, the IFIP Working Group 7.3 Chair, Mark S. Squillante, the previous SIGMETRICS Board Chair, Giuliano Casale, and the past program committee Chairs, Konstantin Avratchenkov, Phillipa Gill, and Bhuvan Urgaonkar, who provided a wealth of information and guidance. Finally, we are grateful to the organization committee and to the SIGMETRICS Board for their ongoing efforts and initiatives for creating an exciting program for ACM SIGMETRICS/Performance 2024.

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Ciucu, Florin, Giulia Fanti e Rhonda Righter. "POMACS V8, N1, March 2024 Editorial". Proceedings of the ACM on Measurement and Analysis of Computing Systems 8, n.º 1 (16 de fevereiro de 2024): 1. http://dx.doi.org/10.1145/3639027.

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The Proceedings of the ACM on Measurement and Analysis of Computing Systems (POMACS) focuses on the measurement and performance evaluation of computer systems and operates in close collaboration with the ACM Special Interest Group SIGMETRICS. All papers in this issue of POMACS will be presented at the ACM SIGMETRICS/Performance 2024 conference on June 10-14, 2024, in Venice, Italy. These papers have been selected during the Fall submission round by the 93 members of the ACM SIGMETRICS/Performance 2024 program committee via a rigorous review process. Each paper was conditionally accepted (and shepherded), allowed a "one-shot" revision (to be resubmitted to one of the subsequent two SIGMETRICS/Performance deadlines), or rejected (with re-submission allowed after a year). For this issue, which represents the Fall deadline, POMACS is publishing 18 papers out of 118 submissions, of which 6 had previously received a one-shot revision decision. All submissions received at least 3 reviews and borderline cases were extensively discussed during the online program committee meeting. Based on the indicated track(s), roughly 33% of the submissions were in the Theory track, 47% were in the Measurement & Applied Modeling track, 39% were in the Systems track, and 19% were in the Learning track (papers could be part of more than one track). Many individuals contributed to the success of this issue of POMACS. First, we would like to thank the authors, who submitted their best work to SIGMETRICS/Performance/POMACS. Second, we would like to thank the program committee members who provided constructive feedback in their reviews to authors and participated in the online discussions and program committee meeting. We also thank the several external reviewers who provided their expert opinions on specific submissions that required additional input. We are also grateful to the SIGMETRICS Board Chair, Mor Harchol-Balter, the IFIP Working Group 7.3 Chair, Mark S. Squillante, the previous SIGMETRICS Board Chair, Giuliano Casale, and the past program committee Chairs, Konstantin Avratchenkov, Phillipa Gill, and Bhuvan Urgaonkar, who provided a wealth of information and guidance. Finally, we are grateful to the Organization Committee and to the SIGMETRICS Board for their ongoing efforts and initiatives for creating an exciting program for ACM SIGMETRICS/Performance 2024.

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Ciucu, Florin, Giulia Fanti e Rhonda Righter. "POMACS V8, N2, June 2024 Editorial". Proceedings of the ACM on Measurement and Analysis of Computing Systems 8, n.º 2 (21 de maio de 2024): 1. http://dx.doi.org/10.1145/3656013.

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The Proceedings of the ACM on Measurement and Analysis of Computing Systems (POMACS) focuses on the measurement and performance evaluation of computer systems and operates in close collaboration with the ACM Special Interest Group SIGMETRICS. All papers in this issue of POMACS will be presented at the ACM SIGMETRICS/IFIP Performance 2024 conference on June 10-14, 2024, in Venice, Italy. These papers were selected during the Winter submission round by the 93 members of the ACM SIGMETRICS/IFIP Performance 2024 program committee via a rigorous review process. Each paper was conditionally accepted (and shepherded), allowed a "one-shot" revision (to be resubmitted to one of the subsequent two SIGMETRICS/Performance deadlines), or rejected (with re-submission allowed after a year). For this issue, which represents the Winter deadline, POMACS is publishing 10 papers out of 127 submissions, of which 2 had previously received a one-shot revision decision. All submissions received at least 3 reviews and borderline cases were extensively discussed during the online program committee meeting. Based on the indicated track(s), roughly 28% of the submissions were in the Theory track, 55% were in the Measurement & Applied Modeling track, 29% were in the Systems track, and 22% were in the Learning track (papers could be part of more than one track). Many individuals contributed to the success of this issue of POMACS. First, we would like to thank the authors, who submitted their best work to SIGMETRICS/Performance/POMACS. Second, we would like to thank the program committee members who provided constructive feedback in their reviews to authors and participated in the online discussions and program committee meeting. We also thank the several external reviewers who provided their expert opinions on specific submissions that required additional input. We are also grateful to the SIGMETRICS Board Chair, Mor Harchol-Balter, the IFIP Working Group 7.3 Chair, Mark S. Squillante, the previous SIGMETRICS Board Chair, Giuliano Casale, and the past program committee Chairs, Konstantin Avrachenkov, Phillipa Gill, and Bhuvan Urgaonkar, who provided a wealth of information and guidance. Finally, we are grateful to the Organization Committee and to the SIGMETRICS Board for their ongoing efforts and initiatives for creating an exciting program for ACM SIGMETRICS/IFIP Performance 2024.

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Faraguna, Martha Caterina, Viola Crescitelli, Anna Fornari, Silvia Barzaghi, Salvatore Savasta, Thomas Foiadelli, Daniele Veraldi, Matteo Paoletti, Anna Pichiecchio e Serena Gasperini. "Treatment Dilemma in Children with Late-Onset Pompe Disease". Genes 14, n.º 2 (30 de janeiro de 2023): 362. http://dx.doi.org/10.3390/genes14020362.

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In recent years, there has been a significant increase in the diagnosis of asymptomatic Late-Onset Pompe Disease (LOPD) patients, who are detected via family screening or Newborn Screening (NBS). The dilemma is when to start Enzyme Replacement Therapy (ERT) in patients without any clinical sign of the disease, considering its important benefits in terms of loss of muscle but also its very high cost, risk of side effects, and long-term immunogenicity. Muscle Magnetic Resonance Imaging (MRI) is accessible, radiation-free, and reproducible; therefore, it is an important instrument for the diagnosis and follow-up of patients with LOPD, especially in asymptomatic cases. European guidelines suggest monitoring in asymptomatic LOPD cases with minimal MRI findings, although other guidelines consider starting ERT in apparently asymptomatic cases with initial muscle involvement (e.g., paraspinal muscles). We describe three siblings affected by LOPD who present compound heterozygosis and wide phenotypic variability. The three cases differ in age at presentation, symptoms, urinary tetrasaccharide levels, and MRI findings, confirming the significant phenotypic variability of LOPD and the difficulty in deciding when to start therapy.

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Colombo, G., C. V. Táparo, E. C. Araújo Júnior, M. Y. Makatu, F. S. Santos e M. Marinho. "Caracterização bioquímica e molecular de Cryptococcus spp. isolados de excretas ambientais de pombos (Columba livia domestica)". Arquivo Brasileiro de Medicina Veterinária e Zootecnia 67, n.º 6 (dezembro de 2015): 1639–45. http://dx.doi.org/10.1590/1678-4162-7753.

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Os pombos possuem uma rica diversidade de microrganismo, entre eles fungos sapróbios, como do gênero Cryptococcus, que podem atuar como agentes patogênicos para o homem e animais. Objetivou-se o isolamento, a caracterização bioquímica e a molecular de amostras de Cryptococcus spp. de excretas ambientas de pombos. Foram colhidas 100 amostras ambientais de pontos equidistantes e representativos da área da cidade de Araçatuba, São Paulo. As amostras foram rasteladas do solo de vias públicas, armazenadas em frasco coletor e encaminhadas para o Laboratório de Bacteriologia e Micologia da FMVA, onde foram processadas e cultivadas em duplicata, em placas de Petri contendo ágar Sabouraud dextrose a 4% e Niger. Em seguida, foram incubadas à temperatura ambiente e a 30ºC, respectivamente, por um período não inferior a 15 dias. Após a observação diária, as colônias sugestivas para levedura foram reisoladas em ágar Niger e submetidas a testes bioquímicos para posterior caracterização molecular pela técnica da PCR. Como resultado, a caracterização bioquímica e a molecular isolaram 32 colônias leveduriformes, sendo 8% dos cultivos positivos para Cryptococcus neoformans var. neoformans, 17% para Rhodotorula rubidae e 7% Candida albicans. Pelo exposto, concluiu-se que excretas ambientais de pombos constituem um microfoco para Cryptococcus neoformans var. neoformans e outras leveduras com potencial patogênico, representando um risco à saúde pública, sendo necessárias medidas preventivas, como a higienização com a correta remoção das excretas, a fim de minimizar os riscos de exposição ambiental.

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Quessard, A., G. Cadier, J. Imbault, J. Rey, M. Pernot e A. Ouattara. "Assistance ventriculaire gauche par Impella® : indications, gestion et complications". Médecine Intensive Réanimation 28, n.º 2 (março de 2019): 114–25. http://dx.doi.org/10.3166/rea-2019-0093.

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L’assistance monoventriculaire Impella® est une assistance microaxiale non pulsatile dépourvue de fonction d’oxygénation et/ou de décarboxylation. Sur le principe de la vis sans fin d’Archimède, elle aspire le sang dans le ventricule gauche pour le réinjecter dans la racine de l’aorte en regard des ostia coronaires. Selon le modèle utilisé, le débit d’assistance antérograde ainsi généré varie de 2,5 à 5 l/min. De par son mode de fonctionnement, l’assistance Impella® permet une décharge ventriculaire efficace. Ses indications sont l’angioplastie coronaire à haut risque et le choc cardiogénique réfractaire aux agents cardiovasoactifs. Chez le patient assisté par une extracorporeal life support (ECLS), la pompe Impella® permet de limiter le risque de surcharge ventriculaire. Chez le patient exclusivement assisté par Impella® soit d’emblée ou après une association avec l’ECLS, la voie d’abord axillaire permet sa réhabilitation active y compris la déambulation et l’activité physique. Elle se révèle alors une mise à l’épreuve cliniquement pertinente du ventricule droit en vue d’une assistance de longue durée de type left ventricular assist device.

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Ashe, Karen M., Kristin M. Taylor, Qiuming Chu, Elizabeth Meyers, Allen Ellis, Varvara Jingozyan, Katherine Klinger et al. "Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease". Molecular Genetics and Metabolism 100, n.º 4 (agosto de 2010): 309–15. http://dx.doi.org/10.1016/j.ymgme.2010.05.001.

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Ashe, K., K. M. Taylor, Q. Chu, E. Meyers, A. Ellis, V. Jingozyan, K. Klinger et al. "Inhibition of Glycogen Biosynthesis via mTORC1 Suppression as an Adjunct Therapy for Pompe Disease". Clinical Therapeutics 33, n.º 6 (junho de 2011): S31. http://dx.doi.org/10.1016/j.clinthera.2011.05.071.

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Resende, Viviane de Melo. "Law Against Rights? A Controversy in São Francisco Square Written in Folha de S. Paulo: Critical-Discursive Reflections". Bakhtiniana: Revista de Estudos do Discurso 17, n.º 3 (setembro de 2022): 35–59. http://dx.doi.org/10.1590/2176-4573e56079.

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ABSTRACT In this paper I present results of a project that, in the context of critical discourse studies and the interdiscursive analysis of public policies, focused on representations in online journalism regarding public policies aimed at the homeless population. The research project (CAPES 88881.172032/2018-01) was developed at the Pompeu Fabra University, Spain. Considering the main newspaper of the city of São Paulo, in its digital platform, we have compiled a comprehensive corpus of news about homeless situation published in a period of three years. The choice to specifically address data from Folha de S Paulo is justified because it is the city with the largest homeless population in Brazil. Also, because our previous study has shown that this is the vehicle, among those studied, that publishes more news related to territorial issues, our focus of interest to investigate via the discursive categories of metaphor and representation of social actors.

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Kreuz, Carlos Leomar, Alceu Souza e José Luiz Petri. "Impacto da intensificação da densidade de plantio na rentabilidade em duas cultivares de macieira em Fraiburgo-SC". Revista Brasileira de Fruticultura 28, n.º 2 (agosto de 2006): 240–43. http://dx.doi.org/10.1590/s0100-29452006000200019.

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Este artigo analisa as expectativas de retorno associadas ao agronegócio da maçã, com base em pomares existentes na região de Fraiburgo-SC. Detalham-se os custos de produção das cultivares Gala e Fuji implantadas em sistemas de alta e superalta densidade. Os resultados indicam ser apenas mediana a rentabilidade do agronegócio em análise. A intensificação tecnológica via ampliação da densidade de plantio, propicia um incremento na rentabilidade. O mesmo pode ser dito da cultivar Fuji em relação à cultivar Gala.

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Fracaro, Antonio Augusto, Fernando Mendes Pereira e Jair Costa Nachtigal. "Uso do Ethephon antes da poda de produção em videira 'Niagara Rosada' (Vitis labrusca L.)". Revista Brasileira de Fruticultura 26, n.º 1 (abril de 2004): 97–100. http://dx.doi.org/10.1590/s0100-29452004000100026.

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Em regiões tropicais e subtropicais do Brasil, a produção de 'Niagara Rosada' tem sido problemática, principalmente devido à dificuldade de emissão e desenvolvimento das brotações após a poda de produção realizada nos meses de ocorrência de temperaturas mais baixas, o que tem causado redução nas produções e desestímulo dos viticultores. Para tentar solucionar esse problema, foram conduzidos três experimentos, em pomares comerciais localizados na região Noroeste do Estado de São Paulo, com o objetivo de estudar o efeito do ethephon, aplicado antes da poda de produção, no desfolhamento da planta, na emissão e desenvolvimento das brotações e na duração do período da poda até a floração. Foram testadas quatro doses de Ethephon (0; 3; 6 e 9 L.ha-1) aplicadas via foliar, 15 dias antes da poda de produção, realizada no mês de junho de 2001. Pelo que foi observado no presente trabalho, o ethephon, embora não causando efeito significativo no número de gemas brotadas, no desenvolvimento das brotações, evidenciou aumento destas variáveis, quando aplicado em pomares pouco enfolhados e em condições climáticas amenas. Com relação ao desfolhamento das plantas, os melhores resultados foram observados nas doses de 6 e 9L.ha-1.

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Sandfeld, Emilie K., Jeffrey Y. Huang, Shih-Hsin Kan e Raymond Y. Wang. "Genomic correction of Pompe disease knock-in mouse myoblasts via CRISPR-Cas9 homology-directed repair". Molecular Genetics and Metabolism 129, n.º 2 (fevereiro de 2020): S143. http://dx.doi.org/10.1016/j.ymgme.2019.11.378.

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Geel, T. M., M. H. J. Ruiters, R. H. Cool, L. Halby, D. C. Voshart, L. Andrade Ruiz, K. E. Niezen-Koning, P. B. Arimondo e M. G. Rots. "The past and presence of gene targeting: from chemicals and DNA via proteins to RNA". Philosophical Transactions of the Royal Society B: Biological Sciences 373, n.º 1748 (23 de abril de 2018): 20170077. http://dx.doi.org/10.1098/rstb.2017.0077.

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The ability to target DNA specifically at any given position within the genome allows many intriguing possibilities and has inspired scientists for decades. Early gene-targeting efforts exploited chemicals or DNA oligonucleotides to interfere with the DNA at a given location in order to inactivate a gene or to correct mutations. We here describe an example towards correcting a genetic mutation underlying Pompe's disease using a nucleotide-fused nuclease (TFO-MunI). In addition to the promise of gene correction, scientists soon realized that genes could be inactivated or even re-activated without inducing potentially harmful DNA damage by targeting transcriptional modulators to a particular gene. However, it proved difficult to fuse protein effector domains to the first generation of programmable DNA-binding agents. The engineering of gene-targeting proteins (zinc finger proteins (ZFPs), transcription activator-like effectors (TALEs)) circumvented this problem. The disadvantage of protein-based gene targeting is that a fusion protein needs to be engineered for every locus. The recent introduction of CRISPR/Cas offers a flexible approach to target a (fusion) protein to the locus of interest using cheap designer RNA molecules. Many research groups now exploit this platform and the first human clinical trials have been initiated: CRISPR/Cas has kicked off a new era of gene targeting and is revolutionizing biomedical sciences. This article is part of a discussion meeting issue ‘Frontiers in epigenetic chemical biology’.

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Jiménez-Morales, Manel, Marta Lopera-Mármol e Alan Salvadó Romero. "Youth empowerment through the creation of i-docs: Educational and social impacts". Catalan Journal of Communication & Cultural Studies 12, n.º 2 (1 de outubro de 2020): 211–24. http://dx.doi.org/10.1386/cjcs_00028_1.

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Information and Communication Technology (ICT) are key elements in the educational process of teens. Consequently, efforts should be made to integrate ICT into educational plans and policies. Based on this premise, HEBE has been launched – a study on youth empowerment that was funded by the Spanish Ministry of Economy and Competitiveness and carried out by five universities: the University of Girona, the Autonomous University of Madrid, the Autonomous University of Barcelona, the University of Barcelona and Pompeu Fabra University. The project, based on media literacy and transmedia skills, involves the creation of an interactive documentary (i-doc). The HEBE i-doc: digital prints relates the experiences and reflections during the maturation stage of six youngsters with different cultural, educational, family and social backgrounds and profiles. This exploration was carried out through their own audio-visual creations, in a life story format. The i-doc has the dual purpose of (1) devising a methodology based on digital ethnography, and (2) creating an interactive platform for sharing experiences and promoting the visibility of these issues via citizen science.

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Boutelleau, C., F. Berard, J. F. Nicolas, A. C. Garreau e A. Nosbaum. "Induction de tolérance à l’omalizumab via une pompe sous-cutanée dans le cadre d’une hypersensibilité retardée". Revue Française d'Allergologie 62, n.º 3 (abril de 2022): 343–44. http://dx.doi.org/10.1016/j.reval.2022.02.131.

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Boudabous, M., L. Chtourou, L. Mnif, A. Grati, A. Amouri e N. Tahri. "Usage des inhibiteurs de la pompe à protons chez le sujet âgé dans la vraie vie". La Revue de Médecine Interne 37 (dezembro de 2016): A155. http://dx.doi.org/10.1016/j.revmed.2016.10.167.

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Hmiri, Shama, Nabila Amrani e Mohamed Rahouti. "Déterminationin vitrode l'activité antifongique des vapeurs d'eugénol et d'huiles essentielles deMentha pulegiumL. et deTanacetum annuumL. vis-à-vis de trois champignons responsables de la pourriture des pommes en post-récolte". Acta Botanica Gallica 158, n.º 4 (janeiro de 2011): 609–16. http://dx.doi.org/10.1080/12538078.2011.10516298.

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Lattuada, Daiane Silva, Mônica Spier e Paulo Vitor Dutra de Souza. "Pré-tratamento com água e doses de ácido indolbutírico para estaquia herbácea de pitangueiras". Ciência Rural 41, n.º 12 (dezembro de 2011): 2073–79. http://dx.doi.org/10.1590/s0103-84782011001200006.

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No Brasil, a maioria dos pomares de pitangueira (Eugenia uniflora) é formada por mudas do tipo pé-franco, o que torna os plantios com baixa uniformidade genética. A propagação vegetativa via estaquia é uma alternativa viável para propagação de diversas espécies frutíferas, podendo ser utilizada também com as espécies nativas, proporcionando a formação de pomares homogêneos, com a produção de mudas com alta sanidade, além de antecipar a produção. Nesse contexto, conduziu-se um estudo visando à multiplicação vegetativa da pitangueira, em que se testou a estaquia herbácea a partir de estacas coletadas de plantas matrizes jovens e adultas, submetidas a três períodos de imersão em água (0, 24 ou 48 horas), além da aplicação de doses de ácido indolbutírico (0, 2000, 4000 e 6000mg L-1). Foram avaliadas a sobrevivência (%), a retenção e a emissão foliar (n° folhas/ estaca), a calogênese (%) e enraizamento das estacas (%). Ao final do experimento, avaliou-se massa fresca e seca de parte aérea e raiz, número de folhas e área foliar. O delineamento experimental foi o completamente casualizado, com três repetições de dez plantas por tratamento para os parâmetros não destrutivos e três repetições de cinco plantas por tratamento para os parâmetros destrutivos. A estaquia herbácea foi eficiente para produzir mudas de pitangueira, especialmente quando utilizadas estacas oriundas de plantas jovens sem necessidade de pré-lavagem nem adição de auxinas exógenas.

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Lima, Márcia Corrêa Queiroz de, Erica Rodrigues Moreira, Aparecida Conceição Boliani, Flávia Aparecida de Carvalho Mariano, Luiz De Souza Correa e Pedro César dos Santos. "AVALIAÇÃO DO TAMANHO DE SEMENTE, SUBSTRATOS E PERÍODO DE ARMAZENAMENTO PARA PRODUÇÃO DE MUDAS DE PITANGUEIRA". Cultura Agronômica: Revista de Ciências Agronômicas 23, n.º 2 (1 de abril de 2014): 91–100. http://dx.doi.org/10.32929/2446-8355.2014v23n2p91-100.

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Alguns estudos mostram que o crescimento das mudas está relacionado ao tamanho da semente e a propagação via sementes é predominante na maioria dos pomares comerciais existentes, o que tem refletido negativamente na condução dos pomares. Para a produção de mudas de pitanga (Eugenia uniflora) o desafio enfrentado é o fato de a semente da pitangueira ser recalcitrante. O trabalho foi desenvolvido em área experimental pertencente a UNESP – Campus de Ilha Solteira, localizada no município de Selvíria-MS em 2009 com o objetivo de avaliar o melhor tamanho de semente, tipo de substrato e a possibilidade de armazenagem das mesmas. O delineamento experimental utilizado foi o de blocos casualizados no esquema fatorial 2 x 4 x 5 (tamanho da semente x tempo de armazenamento x época de plantio), sendo os tratamentos semente grande em vermiculita e plantmax e semente pequena em vermiculita e plantmax, períodos de armazenamento (0, 30, 60 e 90) e os dias após o plantio (15, 30, 45, 60 e 75). As características avaliadas foram: porcentagem de germinação e altura de plântulas. De acordo com os resultados obtidos pode-se concluir que: as sementes grandes apresentaram maiores valores para porcentagem de germinação e altura de plântulas, em relação às sementes pequenas nos dois substratos utilizados, e que é possível o armazenamento em câmara fria por até 30 dias após a secagem das sementes.

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Guan, Xu, Yulan Wang, Zelong Yi e Ying‐Ju Chen. "Inducing Consumer Online Reviews Via Disclosure". Production and Operations Management 29, n.º 8 (10 de junho de 2020): 1956–71. http://dx.doi.org/10.1111/poms.13199.

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Panaino, Antonio. "Astral Omina and their Ambiguity: The Case of Mithridates’ Comets". Iran and the Caucasus 22, n.º 3 (25 de setembro de 2018): 232–56. http://dx.doi.org/10.1163/1573384x-20180303.

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The present article deals with the methodological treatment of the problems connected with the interpretation of a series of astral omina concerning the political life of the Pontus king Mithridates VI Eupator (about 120-63 B.C.), as referred to by Classical authors like Pompeus Trogus (via the Epitomae of Justinus, XXXVII, 2, 1-3) or Seneca (Naturales Quaestiones VII, 15, 2). If some scholars have tried to find the explanation of these events invoking some presumed Iranian religious patterns, this study shows that in reality these attempts are completely groundless, not only with direct reference to the properly Zoroastrian sources, but also to the more complex and pertinent astrological literature. The political use and abuse of these astral events for propaganda needs can be better framed without assuming a pseudo-Iranian favourable vision of the comets or of the falling stars. More reasonably, Mithridates VI, having lived between different cultures, knew well the Mazdean hostile tradition, which considered all these unpredictable celestial bodies as demons, not only and simply for a superstitious hostility, but according to a clearly framed theological interpretation of the world and of its cosmology.

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Mouco, Maria Aparecida do Carmo, Elizabeth Orika Ono e João Domingos Rodrigues. "Inibidores de síntese de giberelinas e crescimento de mudas de mangueira 'Tommy Atkins'". Ciência Rural 40, n.º 2 (fevereiro de 2010): 243–49. http://dx.doi.org/10.1590/s0103-84782010000200004.

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A mangicultura no semiárido brasileiro destaca-se pelos altos rendimentos, pela qualidade do fruto produzido e pela possibilidade de produção durante todo o ano, devido a condições climáticas e tecnologias para o manejo do crescimento vegetativo e da floração, com uso da irrigação, podas e retardantes vegetais. O paclobutrazol aplicado ao solo é utilizado no manejo da produção da mangueira na maioria dos pomares. Entretanto, há a necessidade de identificar retardantes vegetais que possam ser aplicados via foliar, de forma a minimizar os resíduos no solo e evitar o uso de quantidades inadequadas ao longo dos anos. Assim, este trabalho teve como objetivo avaliar retardantes vegetais aplicados via foliar na inibição do crescimento vegetativo de mudas de mangueira 'Tommy Atkins'. Prohexadione-Ca, etil-trinexapac e cloreto de chlormequat, aplicados via foliar, na dose de 1g i.a. planta-1, regulam o crescimento de ramos vegetativos, mas apresentam tempo diferenciado de atividade nas mudas, sendo 20 dias para prohexadione-Ca, 30 dias para cloreto de chlormequat e 45 dias para etil-trinexapac, nas condições em que o experimento foi conduzido.

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Ikusika, Olusegun Oyebade, Oluwakamisi Festus Akinmoladun e Conference Thando Mpendulo. "Enhancement of the Nutritional Composition and Antioxidant Activities of Fruit Pomaces and Agro-Industrial Byproducts through Solid-State Fermentation for Livestock Nutrition: A Review". Fermentation 10, n.º 5 (25 de abril de 2024): 227. http://dx.doi.org/10.3390/fermentation10050227.

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The abundance of fruit waste from the food industry and wineries, particularly peels, seeds, and other fruit pomace throughout the year, could lead to health and environmental hazards if not channelled into productive areas. Improving or transforming these waste products for better use in other vital sectors could be achieved via solid-state fermentation (SSF) since most waste products are solid. One such productive and important area is the feeding of livestock, which will guarantee millennium food security goals for many nations of the world. The nutritional and antioxidant composition of abundantly available fruit pomace and agro-industrial byproducts could be improved via solid-state fermentation for overall livestock productivity. They contain substantial dietary fibre, protein, and phenolic compounds; hence, improving them via fermentation could serve the livestock industry in dual capacities, including nutraceutical and conventional feedstuff. This review seeks to provide reinforcing evidence on the applicability and impact of fruit pomaces on livestock nutrition. The significant nutrient improvements, beneficial outcomes in feeding trials, and inconsistencies or areas of research gap were also explored.

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