Literatura científica selecionada sobre o tema "Polyphénols et flavonoids"
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Artigos de revistas sobre o assunto "Polyphénols et flavonoids"
LAIB, Imen, Hanane KARIT, Rahma BOUZERDOUNA, Fatima KETTOUCHE e Malika BARKAT. "Effet de digestion gastro-intestinale in vitro sur les composés phénoliques et l’activité antioxydante d’ail triquètre Allium triquetrum L." Journal of Applied Biosciences 171 (31 de março de 2022): 17821–37. http://dx.doi.org/10.35759/jabs.171.5.
Texto completo da fonteSerge Cherry, PIBA, KONE N’gana Losséni, KONAN Kouassi Pierre Alain, SOA Jeanol Duvalier, KOUAME Amoin Gervaise, YAO Kouamé Barthélémy, KROA Ehoulé e TRA Bi Fezan Honora. "Phytothérapie et prise en charge des séquelles des accidents vasculaires cérébraux en Côte d’Ivoire". Journal of Animal & Plant Sciences 46, n.º 2 (30 de novembro de 2020): 8197–211. http://dx.doi.org/10.35759/janmplsci.v46-2.4.
Texto completo da fonteToure, Gouanin Larissa, Souleymane Harouna Diete, Lessoy Yves Thierry Zoue e N’Goran David Vincent Kouakou. "Composition chimique, profil en acides gras, criblage phytochimique et activité antioxydante <i>in vitro</i> des graines brutes de <i>Euphorbia heterophylla</i>, une source naturelle riche en Oméga-3". International Journal of Biological and Chemical Sciences 17, n.º 3 (24 de agosto de 2023): 1208–19. http://dx.doi.org/10.4314/ijbcs.v17i3.35.
Texto completo da fonteFotsing, Stela, Marie Paule Ngogang, Nganchouko Bérenger, Louokdom Josué Simo e Jeanne Ngogang. "Teneurs en polyphénols, en flavonoïdes et activités anti oxydantes des rhizomes de Zingiber officinale récoltés dans cinq sites de culture du Cameroun". Journal of the Cameroon Academy of Sciences 18, n.º 2 (24 de outubro de 2022): 397–406. http://dx.doi.org/10.4314/jcas.v18i2.1.
Texto completo da fonteDésiré Diatta, Bétémondji, Ousmane Niass, Massamba Diouf, Mathieu Guèye, Emeline Houel e Gilles Boetsch. "Diversité et composition phytochimique des bâtonnets frotte-dents (cure-dents) proposés chez les Peul de la commune de Tessékéré (Ferlo Nord, Sénégal)". Journal of Applied Biosciences 158 (28 de fevereiro de 2021): 16267–81. http://dx.doi.org/10.35759/jabs.158.1.
Texto completo da fontePiba, Serge Cherry, Pierre Alain Kouassi Konan, Losséni N’gana Kone, Amoin Gervaise Kouame, Richard Kouakoubah Donthy Kouakou e Honora Fezan Bi Tra. "Phytochimie, activité antioxydante et toxicité aiguë de plantes médicinales utilisées contre les séquelles de l’accident vasculaire cérébral en Côte d’Ivoire". International Journal of Biological and Chemical Sciences 15, n.º 2 (22 de junho de 2021): 652–63. http://dx.doi.org/10.4314/ijbcs.v15i2.21.
Texto completo da fonteTraore, Youssouf Zanga, Monon Kone, Brahima Kande e Nathalie Guessennd Kouadio. "Phytochimie et evaluation de la toxicite des extraits de Sida acuta". European Scientific Journal, ESJ 20, n.º 15 (31 de maio de 2024): 164. http://dx.doi.org/10.19044/esj.2024.v20n15p164.
Texto completo da fonteMaguirgue, Kakesse, Honoré Wangso, Jacques-Brice S. Oksom, Issakou Bakaranga-Via, Ngam-Asra Nadjioroum e Brahim Boy Otchom. "Evaluation phytochimique, potentiels antioxydants et anti-inflammatoiresin vitro des extraits des feuilles de Commelina benghalensis Linn. (Commelinaceae)". International Journal of Biological and Chemical Sciences 16, n.º 6 (9 de março de 2023): 2673–84. http://dx.doi.org/10.4314/ijbcs.v16i6.17.
Texto completo da fonteKoffi, Severin, Tianga Yaya Soro, Kouassi Emile Bégbin, N’Guessan Ernest Zougrou, Georges Abizi, Allassane Koné e Koffi Kouakou. "Effets de L’extrait Aqueux des Racines d’Hymenocardia acida (Euphorbiaceae) sur la Qualité du Sperme de Rats". European Scientific Journal, ESJ 18, n.º 24 (31 de julho de 2022): 248. http://dx.doi.org/10.19044/esj.2022.v18n24p248.
Texto completo da fonteAffi Kakou, Baudelaire, Anoubile Benie, Alain Hugues N’Guessan, Konan K. Fernique, N. K. Guessennd e Yves-Alain Bekro. "Phytochemical analysis, antibacterial activity of hydromethanol extracts from stems of Ximenia americana, Côte d’Ivoire species on methicillin-resistant Staphylococcus aureus". International Journal of Biological and Chemical Sciences 14, n.º 9 (26 de março de 2021): 3429–40. http://dx.doi.org/10.4314/ijbcs.v14i9.36.
Texto completo da fonteTeses / dissertações sobre o assunto "Polyphénols et flavonoids"
Tran, Dong tien. "Conception et synthèse de sondes moléculaires pour l'étude d'interactions polyphénol-protéine". Thesis, Bordeaux, 2015. http://www.theses.fr/2015BORD0443/document.
Texto completo da fontePolyphenols are plant secondary metabolites. These natural substances, known for their antioxidant and anti-free radical properties, generally contribute to the protection of human health not only against cardiovascular and neurodegenerative diseases, but also against certain cancers and diabetes. In some cases, these beneficial biological effects could also be related to specific polyphenol-protein interactions. However, studying this type of interactions has suffered from the lack of adequate molecular tools. The work carried out during this thesis has included designing, synthesizing and evaluating modulable polyfunctional molecular probes carrying polyphenols as affinity substrates to analyze polyphenol-protein interactions. In this context, various probes harboring different kinds of polyphenols were synthesized. These probes could be used in chemical proteomics following an “Affinity-Based Protein Profiling” approach (ABPP) to identify a protein within complex protein mixtures, which has a specific affinity with a given polyphenol. These probes will also allow studying the interactions of a polyphenol with a given protein in real time in a qualitative way by surface plasmon resonance (SPR)
Ghnimi, Wafa. "Étude phytochimique des extraits de deux Euphorbiaceae : Ricinus communis et Jatropha curcas. Évaluation de leur propriété anti-oxydante et de leur action inhibitrice sur l’activité de l'acétylcholinestérase". Thesis, Université de Lorraine, 2015. http://www.theses.fr/2015LORR0006/document.
Texto completo da fonteThe aim of this study is to promote two Euphorbiaceae plants the Ricinus communis and the Jatropha curcas, the first one is known for its oil used in the cosmetic products, whereas the second one is known especially for its seeds used in the production of biodiesel. For the castor plant, eight Tunisian populations are studied: Riadh Andalous, Nefza, Beja, Nabeul, Hammamet, Bouficha, Khanguet Hajej and Aouled Amer. For the jatropha, recently introduced in Tunisia, the plant material is collected from the Nabeul station (Tunisia). Eight populations coming from Arusha in Tanzania, Mozambique, Suriname and Brazil from regions of Paraná, Minas Norte, Mato Grosso, Regiao sudeste and Vale do Jequitinhonha are studied. In first, a bibliographic study is made. In second, the used materials and methods are cited. Fanilly, all the results are mentioned. The study shows that the phenolic compounds are higher in the leaves extracts than in the roots extracts for both species. The phytochemical study shows that the gentisic acid is the major phenolic compound identified in the castor plant extracts. In contrast, the epicatechin and the naringin are the most important phenolic compounds identified in the jatropha extracts. The GC-MS analysis reveals that the castor oil contains mainly the ricinoleic acid. For the jatropha oil, two major fatty acids are identified: the oleic and the linoleic acids. Results of the antioxidant properties of leaves and roots of both species indicate a positive correlation between the leaves and the roots activities and their contents of phenolic compounds. Furthermore, the anti-acetylcholinesterase activity of the tested extracts shows for the first time that some tested extracts are more active than the galantamine used as a positive control. Our study confirmed that, in addition to their oils, different extracts of the castor plant and the jatropha can be used for biological activities such as the scavenging free radicals and the inhibitory action of AChE enzyme, which is a major target for treatments against the Alzheimer's disease due to their high levels of phenolic compounds. Owing to the activities of the leaves and the roots extracts confirmed by this study, the agricultural exploitation of the castor plant and the jatropha can be economically more profitable
Achaintre, David. "Développement d’une nouvelle méthode analytique pour le dosage des polyphénols dans les fluides biologiques et application à l’épidémiologie du cancer dans la cohorte EPIC". Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1239/document.
Texto completo da fontePolyphenols are secondary plant metabolites found in diet and more than 500 different compounds are found in more than 450 foods. Along the last 30 years, many in vitro and animals studies have suggested a beneficial role of polyphenols in chronic diseases such as cancer. However, epidemiological studies based mainly on dietary questionnaires are inconsistent. New methodologies with broader polyphenol coverage are required to quantify a large diversity of compounds within large scale epidemiological studies.The goal of this thesis is to develop methods to quantify a large number of polyphenols representative of the main classes and sub-classes in blood and urine, evaluate urinary excretions of polyphenols and their association with food consumption in an European population, evaluate concentrations in blood in a nested case-control study on colorectal cancer within the European prospective investigation study on cancer and nutrition (EPIC).After a short presentation of polyphenols and colorectal cancer in chapter II, an original method based on differential isotopic dilution and analyse by tandem mass spectrometry is developed to quantify 38 polyphenols in urine and presented in chapter III. This method is based on differential 12C-/13C- isotope labelling of polyphenols through derivatisation with isotopic dansyl chloride reagents. Different conditions for enzymatic hydrolysis of conjugated polyphenols, extraction and dansylation of unconjugated aglycones have been tested, optimized and validated for the measure of 37 polyphenols.Urinary excretion levels of these 37 polyphenols in 475 subjects within EPIC cohort from 4 European countries are presented in chapter IV. Large urinary excretion variability in the 4 European countries has been shown and significant correlations with the consumption of specific food containing polyphenols have been observed suggesting the possible used of some polyphenols as biomarker for food consumption.A similar method on plasma for the 37 polyphenols, based on differential isotopic dilution, is developed, validated and applied to 1618 samples within the EPIC cohort (Chapter V). Main changes compared to the method developed on urine are essentially difficulties to hydrolyse conjugated polyphenols and huge matrix effects but reduced by the isotopic dilution method.Finally, the study on the association between polyphenols exposure measured owing to plasmatic marker with colorectal cancer risk has been driven in a nested case-control study within the EPIC cohort and is presented in chapter VI. An inverse association between plasmatic concentrations of equol, and a positive association between homovanillic acid and colon cancer risk have been found.Results obtained constitute a new approach for future applications in large scale epidemiology study on polyphenols
Ben, Nasr Rania. "Investigation phytochimique, évaluation des activités larvicide et anti-acétylcholinestérase de différents extraits de Mercurialis annua L". Electronic Thesis or Diss., Université de Lorraine, 2021. http://www.theses.fr/2021LORR0155.
Texto completo da fonteThis work reports the link between the larvicidal activity and the chemical composition of the different extracts of the male and female feet of Mercurialis annua L. a Euphorbiaceae often used in traditional medicine. The plant material used in our study is collected in four regions of Tunisia located in different bioclimatic stages: Bizerte, Jandouba, Nabeul and Beja. This study includes a first part devoted to a bibliographic synthesis. The second part is devoted to experiments and results. Indeed, we evaluated the antioxidant activity of the different extracts using DPPH tests. The phenolic compounds were identified and quantified by liquid chromatography coupled with a UV detector and mass spectrometry (LC-UV-ESI / MS). Our results showed that methanolic extracts from male plants have higher antioxidant activity (AOA) than that detected in extracts from female plants. On the other hand, male and female plant extracts from Bizerte showed the highest AOA level. For both sexes, Beja plant extracts have the lowest AOA. Certain phenolic compounds such as: narcissin, gallocatechin, rutin, epigallocatechin and epicatechin have been identified and quantified by LC-MS. On the other hand, the larvicidal activity of the various aqueous extracts of Mercurialis annua L. against the larvae of Tribolium confusum (Du Val) showed that the mortality could reach 100% after 48 hours of exposure for certain extracts, this is confirmed. by their low LC50. Furthermore, the study of the anti-acetylcholinesterase activity of the extracts tested shows that they are more potent AChE inhibitors than galantamine used as a positive control.Our study confirmed that extracts of the leaves and seeds of both sexes of Mercurialis annua L., coming from different regions of Tunisia, can therefore be exploited for other biological activities, among which the inhibitory action of AChE. Indeed, these extracts are rich in phenolic compounds, which gives them this therapeutic property against Alzheimer's disease and scavenging free radicals
Le, Nest Gwénaëlle. "Pouvoir antioxydant et piégeur de radicaux libres de polyphénols de vin". Aix-Marseille 1, 2001. http://www.theses.fr/2001AIX11054.
Texto completo da fonteNay, Bastien. "Intérêts, statégies et approches expérimentales en synthèse chimique totale de flavanoi͏̈des et tanins condensés". Bordeaux 2, 1998. http://www.theses.fr/1998BOR2P100.
Texto completo da fonteZupanc, Kauss Tina. "Intérêt thérapeutique et formulation galénique des polyphénols dans le traitement des infections et inflammations". Bordeaux 2, 2007. http://www.theses.fr/2007BOR21501.
Texto completo da fonteImmune response can become a pathological process, leading to a joint matrix destruction in rheumatoid arthritis or to a chronic cachexia in African trypanosomosis. In both pathologies, new therapeutics are needed for a better patients care. Flavonols, non toxic vegetal compounds, could bring a therapeutic alternative in these diseases, but their anti-inflammatory and anti-parasitic effects should be proved and/or characterized. We evaluated therefore the therapeutic potential of two flavonols, quercetin and rutin, in view of their use in human medicine. The effects of non toxic doses of flavonols on macrophage inflammatory mediators' gene transcription and protein expression were studied. In vitro inhibition of TNFα? il1β and NO was also confirmed on rat adjuvant-induced arthritis model, showing a correlation between clinical signs of inflammation (clinical scores and cachexia) and serum inflammatory mediators. In addition, quercetin and rutin trypanocidal effects were demonstrated and the kinetics and dose-response relationship studied. Furthermore, the in vitro trypanocydal effect of vitamin C was highlighted. In vivo studies should confirm the effectiveness of these molecules in African trupanosomosis. A first galenic approach was also conducted in order to improve the bioavailability and consequent therapeutic effects of flavonols
Meng, Linghua. "Caractérisation et extraction par techniques séparatives membranaires de polyphenols actifs et fonctionnels de Perilla frutescens". Aix-Marseille 3, 2007. http://www.theses.fr/2007AIX30045.
Texto completo da fonteThe extraction of polyphenols of Perilla frutescens is optimized at the laboratory scale to obtain a red extract, rich in antioxidant. The extracted polyphenolics are identified by NMR and LC-MS. Coutaric acid, luteolin O-glucuronide and vicenin-2 are for the first time identified in Perilla. The extraction, the purification and the concentration of Perilla extracts in large quantity are carried out at the pilot plant scale using coupled-membrane process: cross-flow microfiltration (CFM) and reverse osmosis (RO) equipped with industrial-type membranes. The microfiltrated extracts were concentrated by RO and/or by evaporation, up to a volume reduction factor of 117. Stabilization of anthocyanin extracts was carried out by spray-drying pilot unit to preserve their antioxidant activity (AOA), determined using DPPH method. AOA and polyphenol composition of 10 Perilla chemovars were compared. Malonylshisonin and rosmarinic acid are the most active compounds amongst all phenolics extracted from Perilla samples
Perruchon, Sophie. "Synthèse et étude des relations structure-fonction des flavonoi͏̈des". Rennes 1, 2004. http://www.theses.fr/2004REN10006.
Texto completo da fonteFargeix, Guillaume. "Étude des mécanismes d'oxydation de flavonoïdes en relation avec leur activité antioxydante : effets anti- et pro-oxydants dans l'inhibition de la peroxydation lipidique par les flavonoïdes". Lyon 1, 2000. http://www.theses.fr/2000LYO10281.
Texto completo da fonte