Literatura científica selecionada sobre o tema "Oriented cell division"
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Artigos de revistas sobre o assunto "Oriented cell division"
Strutt, David. "Organ Shape: Controlling Oriented Cell Division". Current Biology 15, n.º 18 (setembro de 2005): R758—R759. http://dx.doi.org/10.1016/j.cub.2005.08.053.
Texto completo da fonteCastanon, I., e M. González-Gaitán. "Oriented cell division in vertebrate embryogenesis". Current Opinion in Cell Biology 23, n.º 6 (dezembro de 2011): 697–704. http://dx.doi.org/10.1016/j.ceb.2011.09.009.
Texto completo da fonteDewey, Evan, Danielle Taylor e Christopher Johnston. "Cell Fate Decision Making through Oriented Cell Division". Journal of Developmental Biology 3, n.º 4 (14 de dezembro de 2015): 129–57. http://dx.doi.org/10.3390/jdb3040129.
Texto completo da fonteHart, Kevin C., Jiongyi Tan, Kathleen A. Siemers, Joo Yong Sim, Beth L. Pruitt, W. James Nelson e Martijn Gloerich. "E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape". Proceedings of the National Academy of Sciences 114, n.º 29 (3 de julho de 2017): E5845—E5853. http://dx.doi.org/10.1073/pnas.1701703114.
Texto completo da fontede Keijzer, Jeroen, Alejandra Freire Rios e Viola Willemsen. "Physcomitrium patens: A Single Model to Study Oriented Cell Divisions in 1D to 3D Patterning". International Journal of Molecular Sciences 22, n.º 5 (5 de março de 2021): 2626. http://dx.doi.org/10.3390/ijms22052626.
Texto completo da fonteWyatt, Tom P. J., Andrew R. Harris, Maxine Lam, Qian Cheng, Julien Bellis, Andrea Dimitracopoulos, Alexandre J. Kabla, Guillaume T. Charras e Buzz Baum. "Emergence of homeostatic epithelial packing and stress dissipation through divisions oriented along the long cell axis". Proceedings of the National Academy of Sciences 112, n.º 18 (23 de abril de 2015): 5726–31. http://dx.doi.org/10.1073/pnas.1420585112.
Texto completo da fonteMoyle, Louise A., Richard Y. Cheng, Haijiao Liu, Sadegh Davoudi, Silvia A. Ferreira, Aliyah A. Nissar, Yu Sun, Eileen Gentleman, Craig A. Simmons e Penney M. Gilbert. "Three-dimensional niche stiffness synergizes with Wnt7a to modulate the extent of satellite cell symmetric self-renewal divisions". Molecular Biology of the Cell 31, n.º 16 (21 de julho de 2020): 1703–13. http://dx.doi.org/10.1091/mbc.e20-01-0078.
Texto completo da fonteScepanovic, Gordana, e Rodrigo Fernandez-Gonzalez. "Oriented Cell Division: The Pull of the Pole". Developmental Cell 47, n.º 6 (dezembro de 2018): 686–87. http://dx.doi.org/10.1016/j.devcel.2018.11.040.
Texto completo da fonteWalker, Keely L., e Laurie G. Smith. "Investigation of the role of cell-cell interactions in division plane determination during maize leaf development through mosaic analysis of the tangled mutation". Development 129, n.º 13 (1 de julho de 2002): 3219–26. http://dx.doi.org/10.1242/dev.129.13.3219.
Texto completo da fonteConcha, M. L., e R. J. Adams. "Oriented cell divisions and cellular morphogenesis in the zebrafish gastrula and neurula: a time-lapse analysis". Development 125, n.º 6 (15 de março de 1998): 983–94. http://dx.doi.org/10.1242/dev.125.6.983.
Texto completo da fonteTeses / dissertações sobre o assunto "Oriented cell division"
Darby, Daniel. "A mechanism of oriented cell division underlying cardiac chamber expansion". Electronic Thesis or Diss., Sorbonne université, 2019. http://www.theses.fr/2019SORUS666.
Texto completo da fonteThe development of the heart is an intricate process both physically and genetically which requires regulation on many levels. Perturbations of this cardiogenic programme often has potent consequence on the organ and this is evident from the 1% incidence in births which are affected by a congenital heart disease (CHD). CHDs, such as cardiomyopathies, affect the architecture of the cardiac muscle, which is vital to the heartsfunction. The shape of the ventricular walls is particularly important to their function in terms of both defining the shape of the ventricular chambers and in establishing an appropriate myofiber architecture for efficient contractions (Meilhac et al., 2003). Previous work in the lab has provided insight into how this is achieved in the ventricles. It was found, through clonal analysis, that oriented tissue growth underlies cardiac chamber expansion (Meilhac et al., 2004). Analysis of earlier stages of the embryonic heart found regional coordination of cell divisions which preconfigured the myofiber architecture of the adult heart (Le Garrec et al., 2013). These studies suggest that oriented cell division plays an important role in sculpting the heart. However a mechanism by which this is regulated has yet to be established in the expanding ventricular chambers. In this project we use a combination of transcriptomic analysis, 3D cell segmentation, embryo culture experiments and molecular interference to investigate a mechanism for oriented cell division. Using bulk RNAseq we identified the NuMA:GPSM apparatus, the Planar Cell Polarity pathway and the integrin mechano-sensing pathway as candidates for further analysis. In combination with the transcriptomic analysis we wanted to identify if cells in the expanding ventricles were behaving according to Hertwig’s rule. To do this we have established CUBIC clearing and three dimensional lightsheet microscopy along with an automatic cell segmentation method to quantify cell elongations in the cardiac chambers. By comparing the elongation ratio of the cell to the detected axes of division the tools and approaches described above will enable us to identify if coordination existed between the two and if this was regionally specific. To analyse the impact of cardiac contractions on oriented cell division we established embryo culture experiment conditions paired with pharmaceutical interference of contractions. Preliminary results indicate that both an increase and decrease of contraction rate affects the shape of the heart. Finally, we will target the three pathways mentioned above with dominant negative proteins in chimeric hearts to dissect the molecular pathways. The outcome of this research will have potential applications in tissue engineering therapies targeting the heart
Gallini, S. "MOLECULAR CONTRIBUTION OF THE AURORA-A KINASE AND THE JUNCTIONAL PROTEIN AFADIN TO ORIENTED CELL DIVISIONS". Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/354581.
Texto completo da fonteStrauss, Bernhard. "Oriented cell divisions in the Xenopus blastula". Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614211.
Texto completo da fonteFrancou, Alexandre. "Epithelial properties of Second Heart Field cardiac progenitor cells". Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4062.
Texto completo da fonteA major part of the heart is formed by progenitor cells called the second heart field, that contribute to rapid elongation of the heart tube. Defects in second heart field development leads to congenital heart malformations. Second heart field cells are localised in pharyngeal mesoderm in the dorsal pericardial wall. This study focuses on the epithelial properties of second heart field cells and first shows that these progenitors in the dorsal pericardial wall are epithelial and polarised, and form dynamic basal filopodia. Deletion of the transcription factor Tbx1 perturbs epithelial polarity and filopodia formation and upregulates the apical determinant aPKCζ. Treatment with an activator of aPKCζ reveals that epithelial integrity, polarity and basal filopodia are coupled to the progenitor status of second heart field cells. Next we evaluated planar polarity of second heart field cells in the dorsal pericardial wall. Cells are anisotropic, being stretched and elongated on an axis directed towards the arterial pole. This stretch results in oriented epithelial tension revealed by polarised actomyosin accumulation through a negative feedback loop. In the absence of cell addition to the cardiac poles oriented tension is absent. We identified a posterior region in the epithelium with high tension, elevated proliferation and a high level of active YAP/TAZ that may act as relay between tension and proliferation. Oriented tension orients the axis of cell division and the growth of the tissue on an axis toward the arterial pole, further promoting addition of the tissue to the pole. Biomechanical feedback may thus be an important driver of heart tube elongation
Di, Pietro Maria Florencia. "Systematic assessment of the role of Dynein regulators in oriented cell divisions by live RNAi screen in a novel vertebrate model of spindle orientation". Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066405/document.
Texto completo da fonteMitotic spindle orientation is involved in cell fate decisions, tissue homeostasis and morphogenesis. In many contexts, spindle orientation is controlled by the LGN molecular complex, whose subcortical localization determines the site of recruitment of the dynein motor which exerts forces on astral microtubules orienting the spindle. In vertebrates, there is missing information about the molecules regulating the formation of the complex and those working downstream of it. This prompted us to screen for new regulators of vertebrate spindle orientation. For this, I developed a novel model of spindle orientation specifically controlled by the LGN complex. Using this model, I performed a live siRNA screen testing 110 candidates including molecular motors for their function in spindle orientation. Remarkably, this screen revealed that specific dynein regulators contribute differentially to spindle orientation. Moreover, I found that an uncharacterized member of the dynactin complex, the actin capping protein CAPZ-B, is a strong regulator of spindle orientation. Analyses of CAPZ-B function in cultured cells showed that CAPZ-B regulates spindle orientation independently of its classical role in modulating actin dynamics. Instead, CAPZ-B controls spindle orientation by modulating the localization/activity of the dynein/dynactin complexes and the dynamics of spindle microtubules. Finally, we demonstrated that CAPZ-B regulates planar spindle orientation in vivo in the chick embryonic neuroepithelium. I expect that my work will contribute to the understanding of dynein function during vertebrate spindle orientation and will open the path for new investigations in the field
Di, Pietro Maria Florencia. "Systematic assessment of the role of Dynein regulators in oriented cell divisions by live RNAi screen in a novel vertebrate model of spindle orientation". Electronic Thesis or Diss., Paris 6, 2016. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2016PA066405.pdf.
Texto completo da fonteMitotic spindle orientation is involved in cell fate decisions, tissue homeostasis and morphogenesis. In many contexts, spindle orientation is controlled by the LGN molecular complex, whose subcortical localization determines the site of recruitment of the dynein motor which exerts forces on astral microtubules orienting the spindle. In vertebrates, there is missing information about the molecules regulating the formation of the complex and those working downstream of it. This prompted us to screen for new regulators of vertebrate spindle orientation. For this, I developed a novel model of spindle orientation specifically controlled by the LGN complex. Using this model, I performed a live siRNA screen testing 110 candidates including molecular motors for their function in spindle orientation. Remarkably, this screen revealed that specific dynein regulators contribute differentially to spindle orientation. Moreover, I found that an uncharacterized member of the dynactin complex, the actin capping protein CAPZ-B, is a strong regulator of spindle orientation. Analyses of CAPZ-B function in cultured cells showed that CAPZ-B regulates spindle orientation independently of its classical role in modulating actin dynamics. Instead, CAPZ-B controls spindle orientation by modulating the localization/activity of the dynein/dynactin complexes and the dynamics of spindle microtubules. Finally, we demonstrated that CAPZ-B regulates planar spindle orientation in vivo in the chick embryonic neuroepithelium. I expect that my work will contribute to the understanding of dynein function during vertebrate spindle orientation and will open the path for new investigations in the field
Livros sobre o assunto "Oriented cell division"
Kühn, Wolfgang, e Gerd Walz. The molecular basis of ciliopathies and cyst formation. Editado por Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0303.
Texto completo da fonteCapítulos de livros sobre o assunto "Oriented cell division"
Piano, Fabio, e Kenneth Kemphues. "Genetic analysis of intrinsically asymmetrical cell division". In Cell Polarity, 240–68. Oxford University PressOxford, 2000. http://dx.doi.org/10.1093/oso/9780199638031.003.0008.
Texto completo da fonteWolpert, Lewis, Cheryll Tickle, Alfonso Martinez Arias, Peter Lawrence e James Locke. "Plant development". In Principles of Development. Oxford University Press, 2019. http://dx.doi.org/10.1093/hesc/9780198800569.003.0013.
Texto completo da fonteLeón-Mejía, Grethel, Alvaro Miranda Guevara, Ornella Fiorillo Moreno e Carolina Uribe Cruz. "Cytotoxicity as a Fundamental Response to Xenobiotics". In Cytotoxicity - New Insights into Toxic Assessment. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96239.
Texto completo da fontePidoux, Alison L., e Robin C. Allshire. "The structure of yeast centromeres and telomeres and the role of silent heterochromatin". In The Yeast Nucleus, 212–45. Oxford University PressOxford, 2000. http://dx.doi.org/10.1093/oso/9780199637737.003.0007.
Texto completo da fonteDavies, Jamie A. "Morphogenesis by Orientated Cell Division". In Mechanisms of Morphogenesis, 307–23. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-391062-2.00023-1.
Texto completo da fonteDavies, Jamie A. "Morphogenesis by Orientated Cell Division". In Mechanisms of Morphogenesis, 361–77. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-323-99965-6.00002-6.
Texto completo da fonteCarlos Valdés Hernández, Roberto, Juan Gabriel Lopez Hernandez, Adelaida Figueroa Villanueva e Vidblain Amaro Ortega. "Impact of ICT to Improve of the Manufacturing in a SME Biomedical of Mexicali, Mexico". In Concepts, Applications and Emerging Opportunities in Industrial Engineering. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.93585.
Texto completo da fonteTrabalhos de conferências sobre o assunto "Oriented cell division"
Hashimoto, Shigehiro, Hiroki Yonezawa e Ryuya Ono. "Cell Activity Change After Division Under Wall Shear Stress Field". In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-69689.
Texto completo da fonteHashimoto, Shigehiro, e Takashi Yokomizo. "Tracings of Interaction Between Myoblasts Under Shear Flow in Vitro". In ASME 2021 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/fedsm2021-65203.
Texto completo da fontePiqueras, Pedro, Benjamín Pla, Enrique José Sanchis e André Aronis. "Ammonia Slip Estimation Based on ASC Control-Oriented Modelling And OBD NOx Sensor Cross-Sensitivity Analysis". In ASME 2021 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/icef2021-67710.
Texto completo da fonteSpring, Peter, Lino Guzzella e Christopher H. Onder. "Optimal Control Strategy for a Pressure-Wave Supercharged SI Engine". In ASME 2003 Internal Combustion Engine Division Spring Technical Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/ices2003-0645.
Texto completo da fonteMoser, Sean, Simona Onori e Mark Hoffman. "Design and Experimental Validation of a Spatially Discretized, Control-Oriented Temperature Model for a Ceria-Washcoated Gasoline Particulate Filter". In ASME 2018 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/icef2018-9687.
Texto completo da fonteRozenfeld, A., Y. Kozak, T. Rozenfeld e G. Ziskind. "A Novel Double-Pipe Heat Storage Unit". In ASME 2016 Heat Transfer Summer Conference collocated with the ASME 2016 Fluids Engineering Division Summer Meeting and the ASME 2016 14th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/ht2016-7394.
Texto completo da fonteRelatórios de organizações sobre o assunto "Oriented cell division"
Sadot, Einat, Christopher Staiger e Zvi Kam Weizmann. functional genomic screen for new plant cytoskeletal proteins and the determination of their role in actin mediated functions and guard cells regulation. United States Department of Agriculture, janeiro de 2003. http://dx.doi.org/10.32747/2003.7587725.bard.
Texto completo da fonte