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1

Feliu, María, Anabel Impa Condori, Inés Fernandez e Nora Slobodianik. "Omega 3 Fatty Acids vs Omega 6 Fatty Acids". Current Developments in Nutrition 6, Supplement_1 (junho de 2022): 512. http://dx.doi.org/10.1093/cdn/nzac077.015.

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Abstract Objectives Dietary lipids have a very important role in nutrition and must be ingested in an appropriate proportion. Objective: To study the effect of w3 fatty acid supplementation of a diet containing sunflower oil (rich in fatty acids omega 6) as fat source, on serum fatty acid profiles of growing rats. Methods Weanling Wistar rats received during 10 days normocaloric diet and fat was provided by sunflower oil (S group). The others groups received the same diet supplemented with 24mg/day of fish oil (SF group) or chía oil (SCh group). Control group (C) received AIN´93 diet. Serum fatty acids profiles were determined by gas chromatography. Statistical analysis used ANOVA test. Results Results: (expressed as %Area) SERUM: OLEIC C:10.11 ± 1.84, S:12.13 ± 3.84, SCh:12.74 ± 1.56, SF: 13.12 ± 2.82; ARACHIDONIC C:13.40 ± 4.39, S:17.61 ± 4.09, SCh: 15.75 ± 0.89, SF:15.41 ± 1.76; LINOLEIC C:20.52 ± 3.37, S: 19.80 ± 3.36, SCh: 21.14 ± 2.12, SF: 18.92 ± 3.87; LINOLENIC (ALA) C:0.93 ± 0.27a, S:0.19 ± 0.06 b, SCh: 0.28 ± 0.08b, SF:0.22 ± 0.05b; EPA C:0.80 ± 0.22, S:0.68 ± 0.15, SCh: 0.74 ± 0.18, SF: 0.67 ± 0.14; DHA C:1.60 ± 0.55a, S:1.14 ± 0.35a, SCh:1.70 ± 0.45a, SF:4.22 ± 0.93b. Media that didn't present a letter (a, b) in common, were different (p < 0.01). In sera, S, SF and SCh groups showed lower ALA levels compared to C. SF group presented high levels of DHA. Diet S was mainly a contributor to linoleic acid with a ratio w6/w3 = 250 (recommended value: 5–10). Conclusions The diet containing sunflower oil as fat source shows that ω6 family route was exacerbated; by the other hand ω3 family was depressed. Chia supplement showed a tendency towards higher values of w3 family but were significantly lower than C. Fish oil supplement increase significantly DHA values. Diet containing sunflower oil as fat source provoked changes in serum fatty acids profiles and the supplementation with w3 fatty acid provided by chía or fish oil do not increase ALA values significantly. Diet influences the serum fatty acid profile, being not only important the percentage of lipids on it but also the different fatty acids pattern. Funding Sources UBACyT: 20020190100093BA.
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Schmidt, Erik Berg, e Jørn Dyerberg. "Omega-3 Fatty Acids". Drugs 47, n.º 3 (março de 1994): 405–24. http://dx.doi.org/10.2165/00003495-199447030-00003.

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&NA;. "Omega-3-fatty-acids". Reactions Weekly &NA;, n.º 1250 (maio de 2009): 31. http://dx.doi.org/10.2165/00128415-200912500-00092.

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Radack, Kenneth L. "Omega-3 Fatty Acids". Annals of Internal Medicine 109, n.º 1 (1 de julho de 1988): 81. http://dx.doi.org/10.7326/0003-4819-109-1-81.

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Brookhyser, Joan. "Omega 3 Fatty Acids". Journal of Renal Nutrition 16, n.º 3 (julho de 2006): e7-e10. http://dx.doi.org/10.1053/j.jrn.2006.04.003.

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Davidson, Michael H. "Omega-3 fatty acids". Current Opinion in Lipidology 24, n.º 6 (dezembro de 2013): 467–74. http://dx.doi.org/10.1097/mol.0000000000000019.

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Freeman, Marlene P. "Omega-3 fatty acids". Evidence-Based Integrative Medicine 1, n.º 1 (2003): 43–49. http://dx.doi.org/10.2165/01197065-200301010-00008.

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Engler, Marguerite M., e Mary B. Engler. "Omega-3 Fatty Acids". Journal of Cardiovascular Nursing 21, n.º 1 (janeiro de 2006): 17–24. http://dx.doi.org/10.1097/00005082-200601000-00005.

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&NA;. "Omega-3 Fatty Acids". Journal of Cardiovascular Nursing 21, n.º 1 (janeiro de 2006): 25–26. http://dx.doi.org/10.1097/00005082-200601000-00006.

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10

Braquet, P. "Omega-3 fatty acids". Biochimie 75, n.º 11 (janeiro de 1993): 1020–21. http://dx.doi.org/10.1016/0300-9084(93)90158-o.

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Ross, Stephanie Maxine. "Omega-3 Fatty Acids". Holistic Nursing Practice 30, n.º 6 (2016): 382–85. http://dx.doi.org/10.1097/hnp.0000000000000182.

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Vors, C. é. cile, Patrick Couture e Benoît Lamarche. "Omega-3 fatty acids". Current Opinion in Lipidology 31, n.º 1 (fevereiro de 2020): 38–39. http://dx.doi.org/10.1097/mol.0000000000000660.

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Chang, Chuchun L., e Richard J. Deckelbaum. "Omega-3 fatty acids". Current Opinion in Lipidology 24, n.º 4 (agosto de 2013): 345–50. http://dx.doi.org/10.1097/mol.0b013e3283616364.

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Schoenfeld, Brad. "Omega-3 Fatty Acids". Strength and Conditioning Journal 26, n.º 3 (junho de 2004): 72–76. http://dx.doi.org/10.1519/00126548-200406000-00021.

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Boutros, Cherif. "Omega-3 Fatty Acids". Archives of Surgery 145, n.º 6 (1 de junho de 2010): 515. http://dx.doi.org/10.1001/archsurg.2010.91.

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Ross, Stephanie Maxine. "Omega-3 Polyunsaturated Fatty Acids". Holistic Nursing Practice 29, n.º 4 (2015): 245–47. http://dx.doi.org/10.1097/hnp.0000000000000100.

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Pepping, Joseph. "Omega-3 essential fatty acids". American Journal of Health-System Pharmacy 56, n.º 8 (15 de abril de 1999): 719–20. http://dx.doi.org/10.1093/ajhp/56.8.719.

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Hull, Mark A. "Omega-3 polyunsaturated fatty acids". Best Practice & Research Clinical Gastroenterology 25, n.º 4-5 (agosto de 2011): 547–54. http://dx.doi.org/10.1016/j.bpg.2011.08.001.

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19

Jung, Susie. "The functional medicine significance of omega 6 to omega 3 ratio". Korean Institute for Functional Medicine 6, n.º 2 (30 de novembro de 2023): 45–58. http://dx.doi.org/10.32581/jkifm.2023.6.2.45.

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Omega-6 fatty acids and omega-3 fatty acids are essential fatty acids, which should be consumed and supplemented for the functioning of our bodies. The absolute essential fatty acids are linolenic acid and alpha-linolenic acid. However, considering the low conversion rate in vivo and their enzyme activity depending on individual genotype and disease condition, direct intake of gamma-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid is important. Requirements for essential fatty acids may vary from person to person. This means that the omega-6 and omega-3 fatty acid pathways compete to use the same enzymes, the modern Western diet focuses on omega-6 fats, and stress, aging, menopause, and relative deficiencies cause increased inflammation and decreased enzyme activity. The important thing is to consume or supplement fatty acids in a balanced manner rather than supplementing just one kind of 'healthy' fatty acid. Fatty acid imbalance is not a single problem but is complex and organically intertwined, so it usually causes complex problems. Excessive supplementation of one fatty acid can worsen the deficiency of other fatty acids, so wisdom is needed to supplement by checking blood omega-3 index and clinical evidence that can provide appropriate evidence.
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Savatinova, Milena, e Mihaela Ivanova. "Functional dairy products enriched with omega-3 fatty acids". Food Science and Applied Biotechnology 7, n.º 1 (19 de março de 2024): 1. http://dx.doi.org/10.30721/fsab2024.v7.i1.301.

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A critical review was conducted on topics related to functional foods, omega-3 fatty acids, sources of omega-3 fatty acids, and types of dairy products fortified with omega-3 fatty acids. Functional foods are products enriched with special ingredients that give the food beneficial and healthy effects. Inadequate intake of functional foods is directly related to modern diseases, such as atherosclerosis, Alzheimer's, diabete type 2, cardiovascular and autoimmune diseases. Omega-3 and omega-6 are polyunsaturated fatty acids. They have an important biological role for the human body. High omega-6/omega-3 ratios and high amounts of omega-6 lead to a variety of cardiovascular, cancer, inflammatory and autoimmune diseases, while high levels of omega-3 suppress the development of these diseases. Sources of omega-3 fatty acids can be from plants, fish and algae. Dairy products can be enriched with omega-3 fatty acids by modifying the animal's diet or by directly adding vegetable or fish oils. Fresh and mature dairy products enriched with plant and animal sources of omega-3 fatty acids are found in the literature. From the literature review, it was found that there are not enough studies related to the enrichment of Bulgarian dairy products with omega-3 fatty acids.
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Haag, Marianne. "Essential Fatty Acids and the Brain". Canadian Journal of Psychiatry 48, n.º 3 (abril de 2003): 195–203. http://dx.doi.org/10.1177/070674370304800308.

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Objective: To review the role of essential fatty acids in brain membrane function and in the genesis of psychiatric disease. Method: Medline databases were searched for published articles with links among the following key words: essential fatty acids, omega-3 fatty acids, docosahexanoic acid, eicosapentanoic acid, arachidonic acid, neurotransmission, phospholipase A2, depression, schizophrenia, mental performance, attention-deficit hyperactivity disorder, and Alzheimer's disease. Biochemistry textbooks were consulted on the role of fatty acids in membrane function, neurotransmission, and eicosanoid formation. The 3-dimensional structures of fatty acids were obtained from the Web site of the Biochemistry Department, University of Arizona (2001). Results: The fatty acid composition of neuronal cell membrane phospholipids reflects their intake in the diet. The degree of a fatty acid's desaturation determines its 3-dimensional structure and, thus, membrane fluidity and function. The ratio between omega-3 and omega-6 polyunsaturated fatty acids (PUFAs), in particular, influences various aspects of serotoninergic and catecholaminergic neurotransmission, as shown by studies in animal models. Phospholipase A2 (PLA2) hydrolyzes fatty acids from membrane phospholipids: liberated omega-6 PUFAs are metabolized to prostaglandins with a higher inflammatory potential, compared with those generated from the omega-3 family. Thus the activity of PLA2 coupled with membrane fatty acid composition may play a central role in the development of neuronal dysfunction. Intervention trials in human subjects show that omega-3 fatty acids have possible positive effects in the treatment of various psychiatric disorders, but more data are needed to make conclusive directives in this regard. Conclusion: The ratio of membrane omega-3 to omega-6 PUFAs can be modulated by dietary intake. This ratio influences neurotransmission and prostaglandin formation, processes that are vital in the maintenance of normal brain function.
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Ruprich, Jiří, Svatava Bischofová, Helena Pernicová, Zuzana Měřínská, Klára Horáková, Štěpánka Dvořáková, Dagmar Ostrovská, Martina Kalivodová e Irena Řehůřková. "Omega-3 mastné kyseliny v lidské krvi – omega-3 index". Acta hygienica, epidemiologica et microbiologica, n.º 2 (30 de junho de 2021): 1–111. http://dx.doi.org/10.21101/ahem.a1008.

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Aryani, Titin, Fitria Siswi Utami e Sulistyaningsih Sulistyaningsih. "IDENTIFIKASI ASAM LEMAK OMEGA PADA ASI EKSKLUSIF MENGGUNAKAN KROMATOGRAFI GC-MS". Journal of Health Studies 1, n.º 1 (28 de março de 2017): 1–7. http://dx.doi.org/10.31101/jhes.180.

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Abstract: Quantitative research aims to identify the omega fatty acids in exclusive breast milk (ASI) Exclusive. The data analysis used data chromatogram Gas Chromatography-Mass Spectrometry (GC-MS). The data generated is breast milk (ASI) had higher levels of omega-3 fatty acids amounting to 28.24%, omega-6 and omega of 0.57% 9 at 26.56%. The conclusion from this study is there is the content of omega-3, omega-6, omega-9 fatty acids in breast milk (ASI). Highest levels of omega fatty acids in breast milk is the omega-3 fatty acid that is equal to 28.24%.Keywords: milk, omega fatty acids, GC-MS
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Sefer, Dragan, Stamen Radulovic, Dejan Peric, Matija Sefer, Lazar Makivic, Svetlana Grdovic e Radmila Markovic. "Domestic chicken omega 3 – a product for promoting human health". IOP Conference Series: Earth and Environmental Science 854, n.º 1 (1 de outubro de 2021): 012081. http://dx.doi.org/10.1088/1755-1315/854/1/012081.

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Abstract Literature data show that the relationship between two groups of polyunsaturated fatty acids in diet, omega 3 acids, whose basic representative is a-linolenic acid (C18: 3 n-3), and omega 6 acids, whose basic representative is linoleic acid (C18: 2 n-6), has a significant role in development of cardiovascular diseases in humans. The optimal ratio of omega 6 to omega 3 fatty acids is around 4:1. In monogastric animals, the fatty acids in feed are absorbed in the gastrointestinal tract largely unchanged. This means the fatty acid profile of the animal’s diet directly reflects the fatty acid profile of the tissue. The daily intake of unsaturated fatty acids can be increased by an adequate animal nutrition strategy. Flaxseed contains ten times more unsaturated (32.26%) than saturated (3.66%) fatty acids. The largest amount of unsaturated fatty acids (about 70%) is a-linolenic acid (ALA), which is a precursor of the entire omega 3 series of fatty acids, and which makes flaxseed an ideal raw material for the production of a wide range of omega 3 enriched products. In order to obtain chicken meat rich in omega 3, an experiment was organized with a specific diet for broilers at fattening. Thanks to the designed animal feed, it was possible to get products (meat, breast, drumstick, liver, subcutaneous fat) with significantly higher amounts of omega 3 fatty acids compared to the same products obtained from broilers fed with conventional mixtures, or with almost the ideal ratio between omega 6 and omega 3 fatty acids.
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Gören, Jessica L., e Ashley T. Tewksbury. "The Use of Omega-3 Fatty Acids in Mental Illness". Journal of Pharmacy Practice 24, n.º 5 (22 de setembro de 2011): 452–71. http://dx.doi.org/10.1177/0897190011422876.

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Purpose: This article will summarize the current evidence on the effects of omega-3 fatty acids on prevention and treatment of mental illness. Background: Omega-3 fatty acids are involved in many physiologic processes. Since they cannot be made de novo in the body, they are considered essential nutrients. As the Western diet evolved, dietary intake of fatty acids has shifted to increased omega-6 fatty acids and decreased omega-3 fatty acids intake. These changes have been correlated with numerous differences in prevalence and course of mental illnesses. Methods: A MEDLINE search from 1966 to December 2010 was completed to identify studies comparing changes in symptoms, functioning, other outcomes, and/or side effects in patients treated with omega-3 fatty acids for mental illness. The studies were reviewed and reported by specific psychiatric disorder studied. Conclusions: Omega-3 fatty acids play a role in many biologic functions. Epidemiologic data implicate omega-3 fatty acid deficiencies in many mental illnesses. Data are most robust for omega-3 fatty acids' role in affective disorders. However, data are conflicting, negative, or absent for most mental illnesses.
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Chen, Xi, Xue Du, Jianliang Shen, Lizhi Lu e Weiqun Wang. "Original Research: Effect of various dietary fats on fatty acid profile in duck liver: Efficient conversion of short-chain to long-chain omega-3 fatty acids". Experimental Biology and Medicine 242, n.º 1 (4 de outubro de 2016): 80–87. http://dx.doi.org/10.1177/1535370216664031.

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Omega-3 fatty acids, especially long-chain omega-3 fatty acids, have been associated with potential health benefits for chronic disease prevention. Our previous studies found that dietary omega-3 fatty acids could accumulate in the meat and eggs in a duck model. This study was to reveal the effects of various dietary fats on fatty acid profile and conversion of omega-3 fatty acids in duck liver. Female Shan Partridge Ducks were randomly assigned to five dietary treatments, each consisting of 6 replicates of 30 birds. The experimental diets substituted the basal diet by 2% of flaxseed oil, rapeseed oil, beef tallow, or fish oil, respectively. In addition, a dose response study was further conducted for flaxseed and fish oil diets at 0.5%, 1%, and 2%, respectively. At the end of the five-week treatment, fatty acids were extracted from the liver samples and analyzed by GC-FID. As expected, the total omega-3 fatty acids and the ratio of total omega-3/omega-6 significantly increased in both flaxseed and fish oil groups when compared with the control diet. No significant change of total saturated fatty acids or omega-3 fatty acids was found in both rapeseed and beef tallow groups. The dose response study further indicated that 59–81% of the short-chain omega-3 ALA in flaxseed oil-fed group was efficiently converted to long-chain DHA in the duck liver, whereas 1% of dietary flaxseed oil could produce an equivalent level of DHA as 0.5% of dietary fish oil. The more omega-3 fatty acids, the less omega-6 fatty acids in the duck liver. Taken together, this study showed the fatty acid profiling in the duck liver after various dietary fat consumption, provided insight into a dose response change of omega-3 fatty acids, indicated an efficient conversion of short- to long-chain omega-3 fatty acid, and suggested alternative long-chain omega-3 fatty acid-enriched duck products for human health benefits.
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Phillips, MA. "Omega-3 fatty acids, cognitive impairment and Alzheimer's disease". Reviews in Clinical Gerontology 20, n.º 3 (21 de julho de 2010): 219–38. http://dx.doi.org/10.1017/s0959259810000195.

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SummaryThe continued imbalance of fatty acids in western diets has led to concerns about the effect this may be having on physical and mental wellbeing. Diets rich in omega-3 fatty acids, mainly docosahexaenoic acid (DHA) and eicosahexanoic acid (EPA), are argued to help with cardiovascular health as well as cognition. The mechanisms by which this happens are complex and not well understood. However, results from research in this area speculate that individuals with cognitive difficulties may benefit from increasing their omega-3 fatty acid intake, especially if they already show depleted levels of omega-3 fatty acids. This review examines mechanistic reasons behind why low intake of omega-3 fatty acids may affect physical and cognitive health, as well as evidence suggesting diets high in omega-3 fatty acids fend off cognitive disorders. It will also discuss the small body of evidence indicating that omega-3 fatty acids are depleted in those with already manifest cognitive disorders and the possibility that elevating omega-3 fatty acid status in such individuals may benefit their cognition.
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Calder, Philip C., e Parveen Yaqoob. "Understanding Omega-3 Polyunsaturated Fatty Acids". Postgraduate Medicine 121, n.º 6 (1 de novembro de 2009): 148–57. http://dx.doi.org/10.3810/pgm.2009.11.2083.

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Pavlovic, D. M., Aleksandra Pavlovic e Maja Lackovic. "Omega 3 fatty acids in psychiatry". Archives of Biological Sciences 65, n.º 1 (2013): 43–46. http://dx.doi.org/10.2298/abs1301043p.

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Omega-3 long-chain polyunsaturated fatty acids (?-3 LC-PUFAs) are thought to be important for normal dopaminergic, glutamatergic and serotonergic neurotransmission. Depression is less prevalent in societies with high fish consumption, and depressed patients have significantly lower red blood cell ?-3 levels. Studies with ?-3 supplementation have led to controversial results. A significantly longer remission of bipolar symptomatology has been confirmed from a high-dose DHA and EPA mixture. Greater seafood consumption per capita has been connected with a lower prevalence of bipolar spectrum disorders. Reduced levels of ?-6 and ?-3 PUFAs were found in patients with schizophrenia.
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Wadia, Reena. "Periodontitis and omega-3 fatty acids". British Dental Journal 232, n.º 8 (22 de abril de 2022): 533. http://dx.doi.org/10.1038/s41415-022-4212-z.

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Lee, John H., James H. O'Keefe, Carl J. Lavie, Roberto Marchioli e William S. Harris. "Omega-3 Fatty Acids for Cardioprotection". Mayo Clinic Proceedings 83, n.º 3 (março de 2008): 324–32. http://dx.doi.org/10.4065/83.3.324.

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KNAPP, HOWARD R. "Studies of Omega-3 Fatty Acids". Annals of Internal Medicine 108, n.º 5 (1 de maio de 1988): 767. http://dx.doi.org/10.7326/0003-4819-108-5-767_1.

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Simopoulos, Artemis P. "Omega-3 Fatty Acids and Athletics". Current Sports Medicine Reports 6, n.º 4 (agosto de 2007): 230–36. http://dx.doi.org/10.1097/01.csmr.0000306476.80090.8b.

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Laviano, Alessandro, Serena Rianda, Alessio Molfino e Filippo Rossi Fanelli. "Omega-3 fatty acids in cancer". Current Opinion in Clinical Nutrition and Metabolic Care 16, n.º 2 (março de 2013): 156–61. http://dx.doi.org/10.1097/mco.0b013e32835d2d99.

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Zolot, Joan. "Omega-3 Fatty Acids and Antioxidants". AJN, American Journal of Nursing 115, n.º 12 (dezembro de 2015): 68. http://dx.doi.org/10.1097/01.naj.0000475298.35609.ec.

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Ross, Stephanie Maxine. "Omega-3 Fatty Acids, Part I". Holistic Nursing Practice 26, n.º 6 (2012): 356–59. http://dx.doi.org/10.1097/hnp.0b013e3182705e61.

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ASTORG, PIERRE. "Omega-3 Fatty Acids and Depression". American Journal of Psychiatry 162, n.º 2 (fevereiro de 2005): 402—a—402. http://dx.doi.org/10.1176/appi.ajp.162.2.402-a.

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Harris, William S. "Omega-3 Fatty Acids and Health". American Journal of Clinical Nutrition 62, n.º 6 (1 de dezembro de 1995): 1293. http://dx.doi.org/10.1093/ajcn/62.6.1293.

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Calder, Philip C. "Immunomodulation by omega-3 fatty acids". Prostaglandins, Leukotrienes and Essential Fatty Acids 77, n.º 5-6 (novembro de 2007): 327–35. http://dx.doi.org/10.1016/j.plefa.2007.10.015.

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Cole, Greg M., Qiu-Lan Ma e Sally A. Frautschy. "Omega-3 fatty acids and dementia". Prostaglandins, Leukotrienes and Essential Fatty Acids 81, n.º 2-3 (agosto de 2009): 213–21. http://dx.doi.org/10.1016/j.plefa.2009.05.015.

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Mazza, Marianna, Massimiliano Pomponi, Luigi Janiri, Pietro Bria e Salvatore Mazza. "Omega-3 fatty acids and epilepsy". Progress in Neuro-Psychopharmacology and Biological Psychiatry 31, n.º 4 (maio de 2007): 974. http://dx.doi.org/10.1016/j.pnpbp.2007.02.002.

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Hellwig, Jennifer. "Omega-3 Fatty Acids and Depression". Nursing for Women's Health 20, n.º 1 (fevereiro de 2016): 14. http://dx.doi.org/10.1016/s1751-4851(16)00033-7.

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Swingler, D. "Omega-3 fatty acids and mood". Journal of Affective Disorders 107 (março de 2008): S31. http://dx.doi.org/10.1016/j.jad.2007.12.176.

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LEARD-HANSSON, JAN, e Laurence Guttmacher. "Omega-3 Fatty Acids and Depression". Clinical Psychiatry News 33, n.º 5 (maio de 2005): 28. http://dx.doi.org/10.1016/s0270-6644(05)70348-9.

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Mischoulon, David, e Marlene P. Freeman. "Omega-3 Fatty Acids in Psychiatry". Psychiatric Clinics of North America 36, n.º 1 (março de 2013): 15–23. http://dx.doi.org/10.1016/j.psc.2012.12.002.

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Simopoulos, Artemis P. "Omega-3 Fatty Acids and Cancer". Indoor and Built Environment 12, n.º 6 (dezembro de 2003): 405–12. http://dx.doi.org/10.1177/1420326x03036999.

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