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1

Wen, Tengteng, Dehan Luo, Jiafeng He e Kai Mei. "The Odor Characterizations and Reproductions in Machine Olfactions: A Review". Sensors 18, n.º 7 (18 de julho de 2018): 2329. http://dx.doi.org/10.3390/s18072329.

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Machine olfaction is a novel technology and has been developed for many years. The electronic nose with an array of gas sensors, a crucial application form of the machine olfaction, is capable of sensing not only odorous compounds, but also odorless chemicals. Because of its fast response, mobility and easy of use, the electronic nose has been applied to scientific and commercial uses such as environment monitoring and food processing inspection. Additionally, odor characterization and reproduction are the two novel parts of machine olfaction, which extend the field of machine olfaction. Odor characterization is the technique that characterizes odorants as some form of general odor information. At present, there have already been odor characterizations by means of the electronic nose. Odor reproduction is the technique that re-produces an odor by some form of general odor information and displays the odor by the olfactory display. It enhances the human ability of controlling odors just as the control of light and voice. In analogy to visual and auditory display technologies, is it possible that the olfactory display will be used in our daily life? There have already been some efforts toward odor reproduction and olfactory displays.
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2

Gros, A. "Olfaction, émotions et comportements". European Psychiatry 30, S2 (novembro de 2015): S32. http://dx.doi.org/10.1016/j.eurpsy.2015.09.094.

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Le nez a ses raisons que la raison ignore. Les émotions olfactives sont souvent inconscientes et vont pourtant diriger nombreux de nos comportements. Ce lien étroit entre émotion et olfaction est dû au fait que certaines régions cérébrales sont à la fois impliquées dans les processus olfactifs et émotionnels (cortex frontal et amygdale). Dans les pathologies neurodégénératives, dont la maladie d’Alzheimer (MA), ces structures vont être atteintes à des stades plus ou moins sévères de la maladie. Au-delà d’une aide au diagnostic précoce, nous avons montré que l’utilisation d’odorants pourrait aider au diagnostic différentiel entre certains troubles de l’humeur et la maladie d’Alzheimer . Sentir et ressentir, humer et humeur : la langue française nous apporte déjà des preuves d’un lien étroit entre nos émotions et notre olfaction. De manière objective nous avons mis en évidence que les odorants étaient des générateurs d’émotion puissants et stables . Ainsi les odeurs pourraient constituer une alternative non pharmacologique de prise en charge des troubles émotionnels de manière pratique, cette présentation abordera, en premier lieu, le lien précoce entre atteinte olfactive et psycho-comportementale dans la maladie d’Alzheimer puis l’intérêt de la stimulation olfactive dans la prise en charge non médicamenteuse des perturbations émotionnelles et comportementales dans cette pathologie. Pour finir, nous nous interrogerons sur l’apport de l’étude de l’olfaction dans la prise en charge des principaux syndromes émotionnels et thymiques du champ de la pathologie psychiatrique.
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3

Jacquot, L. "Olfaction et troubles cognitifs. Application aux pathologies neurodégénératives". European Psychiatry 30, S2 (novembro de 2015): S31. http://dx.doi.org/10.1016/j.eurpsy.2015.09.093.

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Il est maintenant clairement établi que de nombreuses maladies neurodégénératives, en particulier la maladie de Parkinson et la maladie d’Alzheimer, sont associées à des troubles olfactifs qui peuvent même précéder l’apparition des symptômes moteurs ou cognitifs. Décrits pour la première fois il y a près de quatre décennies [1,2], les déficits de l’olfaction dans ces pathologies ont depuis fait l’objet de nombreuses études qui mettent notamment en avant leur importante prévalence (autour de 95 % pour la maladie de Parkinson ) et leur apparition dans les stades précoces de la maladie . Des travaux récents soulignent ainsi l’intérêt de l’évaluation clinique des déficiences olfactives dans l’établissement du diagnostic précoce ou différentiel. L’objectif de cette présentation est de faire une synthèse de l’état des connaissances sur les déficits olfactifs dans les pathologies neurodégénératives et, en particulier, dans la maladie de Parkinson. La première partie de l’exposé abordera de façon générale les troubles de l’olfaction, leurs étiologies les plus fréquentes et présentera les différents tests permettant l’examen des fonctions olfactives. La deuxième partie portera plus spécifiquement sur la nature et la physiopathologie des altérations olfactives dans la maladie de Parkinson et sur les analogies et les différences avec d’autres pathologies neurodégénératives, notamment la maladie d’Alzheimer. Enfin, une dernière partie présentera les résultats de quelques études récentes montrant les effets bénéfiques potentiels de l’entraînement olfactif sur la récupération de certaines fonctions olfactives.
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4

Pajot-Augy, Édith. "L’haleine et les capteurs d’odeurs". médecine/sciences 35, n.º 2 (fevereiro de 2019): 123–31. http://dx.doi.org/10.1051/medsci/2019001.

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Grâce à leurs capacités olfactives développées, des animaux sont capables de détecter des odeurs associées à certaines pathologies. Récemment, des nez électroniques, consistant en des réseaux de senseurs artificiels générant une signature caractéristique aux odorants présents, par exemple dans l’haleine, permettent à l’heure actuelle de diagnostiquer des pathologies variées, à des stades précoces, et de façon fiable et non invasive. Pour bénéficier de la capacité intrinsèque et naturellement optimisée du système olfactif animal à détecter et discriminer des traces d’odorants, des dispositifs hybrides bioélectroniques sont également en développement pour le diagnostic médical. Ces divers senseurs olfactifs sont en plein essor avec des résultats prometteurs.
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5

Leopold, Donald A. "Olfaction". Current Opinion in Otolaryngology & Head and Neck Surgery 2 (fevereiro de 1994): 22–26. http://dx.doi.org/10.1097/00020840-199402000-00005.

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6

Doty, Richard L. "Olfaction". Annual Review of Psychology 52, n.º 1 (fevereiro de 2001): 423–52. http://dx.doi.org/10.1146/annurev.psych.52.1.423.

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7

Pinto, J. M. "Olfaction". Proceedings of the American Thoracic Society 8, n.º 1 (1 de março de 2011): 46–52. http://dx.doi.org/10.1513/pats.201005-035rn.

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8

McCormick, James. "OLFACTION". Lancet 341, n.º 8853 (maio de 1993): 1126–27. http://dx.doi.org/10.1016/0140-6736(93)93134-m.

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9

de Weert, Ch M. M. "Olfaction". Acta Psychologica 75, n.º 2 (novembro de 1990): 177. http://dx.doi.org/10.1016/0001-6918(90)90092-t.

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10

Yates, Darran. "Connecting olfaction". Nature Reviews Neuroscience 15, n.º 1 (4 de dezembro de 2013): 5. http://dx.doi.org/10.1038/nrn3652.

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11

Mombaerts, Peter. "Targeting olfaction". Current Opinion in Neurobiology 6, n.º 4 (agosto de 1996): 481–86. http://dx.doi.org/10.1016/s0959-4388(96)80053-5.

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12

Beer, Bettina. "Boholano Olfaction". Senses and Society 9, n.º 2 (julho de 2014): 151–73. http://dx.doi.org/10.2752/174589314x13953118734788.

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13

Gilbert, Avery N. "Human olfaction". Appetite 16, n.º 2 (abril de 1991): 166–67. http://dx.doi.org/10.1016/0195-6663(91)90055-w.

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14

Mombaerts, Peter. "Targeting olfaction". IBRO Reports 6 (setembro de 2019): S2. http://dx.doi.org/10.1016/j.ibror.2019.07.170.

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15

Nijland, Reindert, e J. Grant Burgess. "Bacterial olfaction". Biotechnology Journal 5, n.º 9 (18 de agosto de 2010): 974–77. http://dx.doi.org/10.1002/biot.201000174.

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16

Cavedon-Taylor, Dan. "ODORS, OBJECTS, AND OLFACTION". American Philosophical Quarterly 55, n.º 1 (1 de janeiro de 2018): 81–94. http://dx.doi.org/10.2307/45128600.

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Abstract Olfaction represents odors, if it represents anything at all. Does olfaction also represent ordinary objects like cheese, fish, and coffee beans? Many think so. It is argued here that such a view is in error. Instead, we should affirm an austere account of the intentional objects of olfaction: olfactory experience is about odors, not objects. Visuocentric thinking about olfaction has tempted some philosophers to say otherwise.
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17

Pifferi, Massimo, Andrew Bush, Michele Rizzo, Alessandro Tonacci, Maria Di Cicco, Martina Piras, Fabrizio Maggi et al. "Olfactory dysfunction is worse in primary ciliary dyskinesia compared with other causes of chronic sinusitis in children". Thorax 73, n.º 10 (28 de fevereiro de 2018): 980–82. http://dx.doi.org/10.1136/thoraxjnl-2017-210661.

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Cilia have multiple functions including olfaction. We hypothesised that olfactory function could be impaired in primary ciliary dyskinesia (PCD). Olfaction, nasal nitric oxide (nNO) and sinus CT were assessed in patients with PCD and non-PCD sinus disease, and healthy controls (no CT scan). PCD and non-PCD patients had similar severity of sinus disease. Despite this, defective olfaction was more common in patients with PCD (P<0.0001) and more severe in patients with PCD with major Transmission Electron Microscopy (TEM) abnormalities. Only in classical PCD did olfaction inversely correlate with sinusitis and nNO. We speculate that defective olfaction in PCD is primary in nature.
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18

Tian, Qu, Murat Bilgel, Abhay R. Moghekar, Luigi Ferrucci e Susan M. Resnick. "Olfaction, Cognitive Impairment, and PET Biomarkers in Community-Dwelling Older Adults". Journal of Alzheimer's Disease 86, n.º 3 (5 de abril de 2022): 1275–85. http://dx.doi.org/10.3233/jad-210636.

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Background: Olfactory deficits are early features of preclinical Alzheimer’s disease (AD). Whether olfaction is associated with PET biomarkers among community-dwelling older adults is less clear. Objective: Investigate cross-sectional and longitudinal associations of olfaction with mild cognitive impairment (MCI) and amyloid-β (Aβ) and tau deposition. Methods: We analyzed 364 initially cognitively normal participants (58% women, 24% black) who had baseline olfaction data and subsequent cognitive assessments during an average 2.4-year. A subset of 129 had PET-PiB (Aβ) (n = 72 repeated) and 105 had 18F-flortaucipir (FTP)-PET (tau) (n = 44 repeated). Olfaction was measured using a 16-item Sniffin’ Sticks Odor Identification Test. The association of olfaction with incident MCI was examined using Cox regression. Associations with PiB-distribution volume ratio (DVR) and FTP-standardized uptake value ratio (SUVR) were examined using partial correlation. We tested whether PiB+/–status modified these associations. Analyses were adjusted for demographics and olfactory test version. Results: 17 (5%) participants developed MCI. Each unit lower odor identification score was associated with 22% higher risk of developing MCI (p = 0.04). In the PET subset, lower scores were associated with higher mean cortical DVR and DVR in orbitofrontal cortex (OFC), precuneus, and middle temporal gyrus (p≤0.04). The “olfaction*PiB+/–” interaction in OFC DVR was significant (p = 0.03), indicating the association was limited to PiB positive individuals. Greater decline in odor identification score was associated with greater increase in anterior OFC DVR and entorhinal tau SUVR (p≤0.03). Conclusion: Among community-dwelling older adults, poorer olfaction predicts incident MCI and is associated with overall and regional Aβ. Greater olfaction decline is associated with faster Aβ and tau accumulation in olfaction-related regions. Whether olfaction predicts AD-related neurodegenerative changes warrants further investigations.
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19

Giorgi, D., e S. Rouquier. "L'inactivation des gènes des récepteurs olfactifs peut-elle rendre compte de la diminution des capacités olfactives des primates ?" médecine/sciences 14, n.º 11 (1998): 1262. http://dx.doi.org/10.4267/10608/950.

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20

Carvalho, Felipe. "Olfactory Objects". Disputatio 6, n.º 38 (1 de maio de 2014): 45–66. http://dx.doi.org/10.2478/disp-2014-0003.

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Abstract The philosophy of perception has been mostly focused on vision, to the detriment of other modalities like audition or olfaction. In this paper I focus on olfaction and olfactory experience, and raise the following questions: is olfaction a perceptual-representational modality? If so, what does it represent? My goal in the paper is, firstly, to provide an affirmative answer to the first question, and secondly, to argue that olfaction represents odors in the form of olfactory objects, to which olfactory qualities are attributed. In order to do this I develop an empirically adequate notion of olfactory object that is sensitive to the peculiarities of olfaction, and defend it against various objections.
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21

Huang, C. "Detection of prey by captive Ningaui ridei and Sminthopsis griseoventer (Marsupialia: Dasyuridae)." Australian Mammalogy 10, n.º 1 (1 de janeiro de 1987): 23–26. http://dx.doi.org/10.1071/am87003.

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The role of olfaction, vision and hearing in prey detection was investigated in Sminthopsis griseoventer and Ningaui ridei. Prey were presented so that they could be detected by one or a combination of these senses. When prey was presented so that only one sense could be used, prey were detected only by olfaction. When prey were presented so that two or all senses could be used, prey detection was fastest when all three senses were used and faster when hearing was used in combination with olfaction than when vision was used in combination with olfaction. It is suggested that hearing and vision may direct prey investigation by olfaction, and so speed location of prey.
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22

Shrestha, Srishti, Xiaoqian Zhu, Kevin Sullivan, Beverly Gwen Windham, Jennifer Deal, Honglei Chen, Michael Griswold e Thomas Mosley. "OLFACTORY IMPAIRMENT AND MICROSTRUCTURAL INTEGRITY OF THE BRAIN IN THE ARIC STUDY". Innovation in Aging 6, Supplement_1 (1 de novembro de 2022): 151. http://dx.doi.org/10.1093/geroni/igac059.604.

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Abstract We examined cross-sectional associations between microstructural integrity of the brain and olfaction in 1417 participants from the ARIC Study who completed MRI scans in 2011-2013 (mean age=76±2 years, 41% male). Microstructural integrity was measured by two diffusion tensor imaging measures, fractional anisotropy (FA, higher=better) and mean diffusivity (MD, higher=worse), and olfaction by a 12-item odor-identification test. In multivariable linear regression models, higher FA in several regions was associated with better olfaction, with the strongest association in the stria terminalis [β:0.333 (95%CI:0.188, 0.478) per standard deviation (SD) higher FA]. Higher MD was associated with lower olfaction in almost all regions, but associations were strongest for some temporal sub-regions [for example, hippocampus, β:-0.796 (95%CI: -0.942, -0.651) per SD higher MD]. Our findings suggest that neuronal microstructural integrity is an important predictor of olfaction; this may also have important implications in understanding early dementia neuropathology as olfaction is affected very early in dementia.
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23

DUNN, TREVOR P., e MALCOLM P. I. WELLER. "OLFACTION IN SCHIZOPHRENIA". Perceptual and Motor Skills 69, n.º 3 (dezembro de 1989): 833–34. http://dx.doi.org/10.2466/pms.1989.69.3.833.

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24

Ballenger, John J. "Olfaction—A Review". American Journal of Rhinology 1, n.º 3 (setembro de 1987): 113–18. http://dx.doi.org/10.2500/105065887781693457.

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25

Lledo, Pierre-Marie, Alan Carleton e Jean-Didier Vincent. "Odeur et olfaction". Journal de la Société de Biologie 196, n.º 1 (2002): 59–65. http://dx.doi.org/10.1051/jbio/2002196010059.

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26

Dunn, Trevor P., e Malcolm P. I. Weller. "Olfaction in Schizophrenia". Perceptual and Motor Skills 69, n.º 3-1 (dezembro de 1989): 833–34. http://dx.doi.org/10.1177/00315125890693-121.

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27

Hirsch, Alan R. "Olfaction in Migraineurs". Headache: The Journal of Head and Face Pain 32, n.º 5 (maio de 1992): 233–36. http://dx.doi.org/10.1111/j.1526-4610.1992.hed3205233.x.

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28

Bodo, Cristian. "Olfaction goes digital". Nature Reviews Neuroscience 11, n.º 6 (junho de 2010): 373. http://dx.doi.org/10.1038/nrn2859.

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29

Snyder, RD, e PD Drummond. "Olfaction in Migraine". Cephalalgia 17, n.º 7 (novembro de 1997): 729–32. http://dx.doi.org/10.1046/j.1468-2982.1997.1707729.x.

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Olfactory thresholds for acetone and vanillin and the unpleasantness rating of concentrated acetone were measured in 20 migraine sufferers and 21 controls. The olfactory threshold for vanillin was lower in migraine sufferers than in controls. In addition, patients who reported that odours frequently seemed stronger during attacks of migraine were able to detect acetone, at a lower concentration than most other patients. No differences were found between migraine sufferers and controls for ratings of the unpleasantness of concentrated acetone. These findings suggest that hyperacuity to odours persists between episodes of migraine. Sensitivity to odours could contribute to the migraine predisposition.
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30

Hirsch, AR. "Olfaction in Migraine". Cephalalgia 18, n.º 6 (agosto de 1998): 360. http://dx.doi.org/10.1046/j.1468-2982.1998.1806358-3.x.

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31

Bromley, SM, e RL Doty. "Olfaction in dentistry". Oral Diseases 16, n.º 3 (abril de 2010): 221–32. http://dx.doi.org/10.1111/j.1601-0825.2009.01616.x.

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32

Potier, Simon. "Olfaction in raptors". Zoological Journal of the Linnean Society 189, n.º 3 (20 de outubro de 2019): 713–21. http://dx.doi.org/10.1093/zoolinnean/zlz121.

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Abstract Raptors from the orders Accipitriformes and Falconiformes have been considered to rely principally on vision. Historically, this assumption has led scientists to discount any possible sense of smell in these birds, until work on cathartid vultures indicated that these species at least rely on olfaction to find carrion. In this review I provide evidence that raptors in general have functional olfactory systems that they may use in a range of different contexts. Anatomical studies show that raptors have well-developed olfactory bulbs that are within the range of other bird species. Furthermore, all raptors studied have multiple functional olfactory genes, with, for instance, 283 olfactory genes in the Oriental honey buzzard, Pernis orientalis, of which 81.5% are functional. It has also been shown that some raptors species may functionally use olfactory cues to forage and, potentially, for communication. While further research is required, the available evidence suggests that olfaction may be a more important sensory modality in these birds than previously thought.
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33

Serby, M., J. Corwin, A. Novatt, P. Conrad e J. Rotrosen. "Olfaction in dementia." Journal of Neurology, Neurosurgery & Psychiatry 48, n.º 8 (1 de agosto de 1985): 848–49. http://dx.doi.org/10.1136/jnnp.48.8.848-c.

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34

Murray, Niall, Brian Lee, Yuansong Qiao e Gabriel-Miro Muntean. "Olfaction-Enhanced Multimedia". ACM Computing Surveys 48, n.º 4 (2 de maio de 2016): 1–34. http://dx.doi.org/10.1145/2816454.

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35

Doty, Richard L. "Science of Olfaction". Journal of Nervous and Mental Disease 182, n.º 6 (junho de 1994): 363–64. http://dx.doi.org/10.1097/00005053-199406000-00013.

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36

Fong, Karen J. "Olfaction and taste". Otolaryngologic Clinics of North America 37, n.º 6 (dezembro de 2004): xi—xii. http://dx.doi.org/10.1016/j.otc.2004.09.009.

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37

Vosshall, Leslie B. "Olfaction in Drosophila". Current Opinion in Neurobiology 10, n.º 4 (agosto de 2000): 498–503. http://dx.doi.org/10.1016/s0959-4388(00)00111-2.

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38

Serratrice, G., J. P. Azulay e J. Serratrice. "Olfaction et gustation". EMC - Neurologie 3, n.º 1 (janeiro de 2006): 1–10. http://dx.doi.org/10.1016/s0246-0378(06)41737-1.

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39

Serratrice, J., e G. Serratrice. "Olfaction et gustation". EMC - Neurologie 10, n.º 1 (janeiro de 2013): 1–11. http://dx.doi.org/10.1016/s0246-0378(12)60762-3.

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40

Blanchard, D. Caroline, Robert J. Blanchard e Jeffrey Rosen. "Olfaction and defense". Neuroscience & Biobehavioral Reviews 32, n.º 7 (setembro de 2008): 1207–8. http://dx.doi.org/10.1016/j.neubiorev.2008.07.003.

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41

Jones, Nick, e David Rog. "Olfaction: a review". Journal of Laryngology & Otology 112, n.º 1 (janeiro de 1998): 11–24. http://dx.doi.org/10.1017/s0022215100139829.

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42

Spence, Charles, Francis McGlone, Birgit Kettenmann e Gerd Kobal. "Attention to olfaction". Experimental Brain Research 138, n.º 4 (1 de junho de 2001): 432–37. http://dx.doi.org/10.1007/s002210100713.

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43

Cinelli, Angel R. "Science of Olfaction". Trends in Neurosciences 16, n.º 3 (março de 1993): 123–24. http://dx.doi.org/10.1016/0166-2236(93)90137-b.

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44

Bonadonna, Francesco. "Olfaction in Petrels". Annals of the New York Academy of Sciences 1170, n.º 1 (julho de 2009): 428–33. http://dx.doi.org/10.1111/j.1749-6632.2009.03890.x.

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45

Harrison, P. J., e R. C. A. Pearson. "Olfaction and Psychiatry". British Journal of Psychiatry 155, n.º 6 (dezembro de 1989): 822–28. http://dx.doi.org/10.1192/bjp.155.6.822.

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Recent clinical studies have identified significant olfactory deficits in several neuropsychiatric disorders, notably Alzheimer's disease and Parkinson's disease. These have correlated with neurochemical and neuropathological studies of the olfactory system. The presence of a specific sensory deficit may be related to the localisation of pathology within the brain. There is a need for incorporation of olfactory testing into routine clinical examination.
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46

Verghese, Abraham, e A. Abraham. "Olfaction and psychiatry". British Journal of Psychiatry 156, n.º 5 (maio de 1990): 749. http://dx.doi.org/10.1192/bjp.156.5.749a.

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47

Leopold, Donald A., e Sande Bartels. "Evaluation of Olfaction". Journal of Otolaryngology 31, S1 (2002): S18. http://dx.doi.org/10.2310/7070.2002.21263.

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48

Souza, Fabio Marques Simoes de, e Gabriela Antunes. "Biophysics of olfaction". Reports on Progress in Physics 70, n.º 3 (21 de fevereiro de 2007): 451–91. http://dx.doi.org/10.1088/0034-4885/70/3/r04.

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