Bibliografias temáticas / Neovascularisation

Índice

Artigos de revistas
Teses / dissertações
Livros
Capítulos de livros
Trabalhos de conferências

Literatura científica selecionada sobre o tema "Neovascularisation"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 20 de julho de 2024

Crie uma referência precisa em APA, MLA, Chicago, Harvard, e outros estilos

Selecione um tipo de fonte:

Consulte a lista de atuais artigos, livros, teses, anais de congressos e outras fontes científicas relevantes para o tema "Neovascularisation".

Ao lado de cada fonte na lista de referências, há um botão "Adicionar à bibliografia". Clique e geraremos automaticamente a citação bibliográfica do trabalho escolhido no estilo de citação de que você precisa: APA, MLA, Harvard, Chicago, Vancouver, etc.

Você também pode baixar o texto completo da publicação científica em formato .pdf e ler o resumo do trabalho online se estiver presente nos metadados.

Artigos de revistas sobre o assunto "Neovascularisation"

Creton, D. "Neovascularisation". Phlebologie 37, n.º 03 (maio de 2008): 134–41. http://dx.doi.org/10.1055/s-0037-1622223.

Texto completo da fonte

Resumo:

SummaryThere are different causes of neovascularisation: vascular endothelial growth factor, inflammatory process, hypertrophy of pre-existant vessels (lymph node veins), haematomas revascularisation, and high difference in pressure. The latter 3 depend directly on the way the operation is performed hence on the surgeon.Concerning the primary varices patch saphenoplasty do not abolish neovascularisation. It is of first importance to perform a flush ligation only in case of incontinent terminal and pre-terminal valves. In that case an incision as small as possible must be carried out with minimal dissection and with tumescence to limit the bleeding and hematomas. When the terminal valve is competent it is better to choose endovascular technique.Concerning re-do it is mandatory to avoid useless re-do, the best choice is foam sclerotherapy. I am convinced that neovascularisation are produced by the complications which are induced by a large dissection. The barrier technique are, probably, not as useful as we was told 10 years ago. The lack of aggressiveness during the operation is certainly far more important: “Doing less in the groin to do better for the recurrence and re-recurrence”

Estilos ABNT, Harvard, Vancouver, APA, etc.

Holmgren, L. "Malignant Neovascularisation". European Journal of Ultrasound 6 (novembro de 1997): S11. http://dx.doi.org/10.1016/s0929-8266(97)87215-1.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Smith, R. "Neovascularisation again." British Journal of Ophthalmology 74, n.º 6 (1 de junho de 1990): 323. http://dx.doi.org/10.1136/bjo.74.6.323.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Badal, Josep, Luis Amselem, Ricardo Aleman e Frederic Huste. "Anti–vascular Endothelial Growth Factor Therapy for Myopic Choroidal Neovascularisation". European Ophthalmic Review 07, n.º 02 (2013): 84. http://dx.doi.org/10.17925/eor.2013.07.02.84.

Texto completo da fonte

Resumo:

Pathological myopia represents the most common cause of choroidal neovascularisation in young patients. Its natural course has a devastating prognosis. Several treatments have been assessed, but photodynamic therapy is currently the only approved treatment for subfoveal choroidal neovascularisation related to pathological myopia. Anti-vascular endothelial growth factor therapy has demonstrated promising results in any form and localisation of choroidal neovascularisation, although there is an absence of data obtained from randomised clinical trials. The aim of this article is to compare different treatment options, combinations and retreatment criteria for the management of choroidal neovascularisation in eyes with high myopia.

Estilos ABNT, Harvard, Vancouver, APA, etc.

Imre, G. "Lactic acid neovascularisation." British Journal of Ophthalmology 75, n.º 4 (1 de abril de 1991): 254. http://dx.doi.org/10.1136/bjo.75.4.254.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Shehadeh, Mohammad M., Mohammad T. Akkawi, Vasilios F. Diakonis, Ammar A. Aghbar e Abdelraheem Abu Shanab. "Extensive Corneal Neovascularisation Treatment by Ultraviolet Corneal Collagen Crosslinking". European Ophthalmic Review 11, n.º 01 (2017): 62. http://dx.doi.org/10.17925/eor.2017.11.01.62.

Texto completo da fonte

Resumo:

The purpose of this article is to report a case of extensive corneal neovascularisation that was treated by ultraviolet corneal collagen crosslinking (CXL). The case report is about a 24-year-old man who was referred to the cornea clinic with a case of keratitis. He was treated with topical antibiotics. After full resolution of keratitis, his condition was complicated by extensive corneal neovascularisation. A trial of photochemical corneal collagen CXL with riboflavin/ultraviolet A resulted in a dramatic improvement and resolution of the corneal neovascularisation. Thus, we can conclude that corneal collagen CXL could be a promising procedure to treat certain cases of extensive corneal neovascularisation.

Estilos ABNT, Harvard, Vancouver, APA, etc.

Cheng, Jacob YC, Doric WK Wong e Chong Lye Ang. "Intraocular Avastin (Bevacizumab) for Neovascularisation of the Iris and Neovascular Glaucoma". Annals of the Academy of Medicine, Singapore 37, n.º 1 (15 de janeiro de 2008): 72–74. http://dx.doi.org/10.47102/annals-acadmedsg.v37n1p72.

Texto completo da fonte

Resumo:

Introduction: The aim of this study was to determine the effectiveness of intraocular injections of bevacizumab for neovascularisation of the iris and neovascular glaucoma. Clinical Picture: Three patients with neovascularisation of the iris due to various causes were recruited. Treatment: Patients were treated with intraocular bevacizumab. Outcome: Neovascularisation of the iris was noted to have completely regressed as early as 3 days after the injection and in all the patients (100%) within 8 days after injection. They were followed up for at least 1 month with no clinical evidence of recurrence. Visual acuity remained stable or improved, and the intraocular pressure was controlled in all the 3 patients’ eyes. Vitreous haemorrhage also cleared. No signs of inflammation or complications were observed. Conclusion: Intraocular injection of bevacizumab is effective and safe for patients with neovascularisation of the iris and neovascular glaucoma with or without vitreous haemorrhage. Key words: Intravitreal, Vascular endothelial growth factor, Vitreous haemorrhage

Estilos ABNT, Harvard, Vancouver, APA, etc.

Buragohain, Suklengmung, Harsha Bhattacharjee e Henal Javeri. "Capsular neovascularisation in uveitis". Indian Journal of Ophthalmology - Case Reports 1, n.º 3 (2021): 458. http://dx.doi.org/10.4103/ijo.ijo_3625_20.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Faraj, L. A., D. G. Said e H. S. Dua. "Evaluation of corneal neovascularisation". British Journal of Ophthalmology 95, n.º 10 (21 de setembro de 2011): 1343–44. http://dx.doi.org/10.1136/bjophthalmol-2011-300856.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Stavrou, D. "Neovascularisation in wound healing". Journal of Wound Care 17, n.º 7 (julho de 2008): 298–302. http://dx.doi.org/10.12968/jowc.2008.17.7.30521.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Mais fontes

Teses / dissertações sobre o assunto "Neovascularisation"

Faraj, Lana Akram. "Corneal neovascularisation : evaluation, pathology and treatment". Thesis, University of Nottingham, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718466.

Texto completo da fonte

Resumo:

The cornea is the clear window of the eye and its main refractive media. Corneal avascularity is essential to maintain this function, and this is evolutionarily highly conserved. Corneal vascularisation can result from different types of insults, causing reduced vision and posing a threat to the survival of corneal grafts. We prospectively reviewed 165 patients with corneal vascularisation establishing a reproducible classification of corneal vessels. We classified corneal vessels in to young active, old active, mature, partially regressed and regressed vessels. Patterns of vascularisations differed with aetiology as viral keratitis inducing more severe vascularisation most association with lipid deposition in the cornea. Acanthamoeba keratitis however induced less vascularisation despite severe corneal inflammation. Fine needle diathermy was found to be safe and effective method of treating corneal vascularisation and its effectiveness could be improved further by appropriate selection. Subconjunctival injection of Ranibizumab, which is a fragment of a monoclonal antibody (Fab) created form the same mouse antibody as bevacizumab, was effective in regressing corneal vascularisation initially; this was not maintained with a single dose in the presence of active inciting inflammatory process in the cornea. This reinforces the dictum that as long as the stimulus for vascularisation is not addressed measures to reduce vascularisation have only a temporary effect. Fine needle diathermy and anti angiogenic treatments can form components of an overall strategy to mitigate risk of rejection or in dealing with refractory episodes of rejection in the cornea. Isolation of conjunctival vascular endothelial cells proved very challenging. The widely used human umbilical cord endothelial cells also proved great variation in their cell surface marker expression and phenotypic characteristics across different passages. This highlighted the wide variation to be expected and the need for specificity in the targeted population of cells used in designing angiogenesis experiments. With the use of human umbilical cord endothelial cells we demonstrated the in-vitro anti angiogenic effect of the amniotic membrane. The amniotic membrane significantly reduced endothelial cell proliferation, migration and tube formation.

Estilos ABNT, Harvard, Vancouver, APA, etc.

Balaggan, K. S. "Development of gene therapy for choroidal neovascularisation". Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1335615/.

Texto completo da fonte

Resumo:

Exudative age-related macular degeneration, characterised by choroidal neovascularisation (CNV), is the leading cause of severe visual impairment in developed societies. Until recently, established treatments were of limited efficacy, and associated with other disadvantages including being inherently destructive therapies. Although novel anti-VEGF pharmacotherapy has since revolutionised the management and prognosis of many patients, current treatment regimens have distinct limitations, particularly in terms of the probable requirement for life-long, frequent invasive dosing, and associated cumulative medical, financial and logistical consequences. Furthermore, many patients respond suboptimally despite frequent administration. Continued development of superior therapies, therefore remains essential. Targeted angiostatic gene delivery may achieve many of the characteristics required of an ideal treatment modality. Work is presented which further expands the possibility of safe and efficacious retinal gene therapy by viral methods, for the ultimate intention of controlling human CNV. Proof of principle is demonstrated for in vivo intraocular expression from equine infectious anaemia virus-based vectors and non-integrating HIV-1-based vectors, which both represent significant advances in biosafety. The angiostatic efficacies of sFlt-1, endostatin, angiostatin and Pedf are then evaluated in an established murine laser model of CNV. This model is further optimised to quantify CNV-associated hyperpermeability in addition to CNV area. Lentiviral transfer of sFlt-1, endostatin or angiostatin, and Pedf upregulation by bespoke zinc finger transcription factors delivered by adeno-associated viral vectors potently inhibited angiogenesis, with sFlt-1, endostatin and angiostatin additionally inhibiting CNV-associated hyperpermeability. Finally, a novel angiogenic role of sonic hedgehog signalling in experimental CNV is identified, and its pharmacological inhibition demonstrated to be angiostatic. These results complement the current body of experimental evidence, which coupled with the demonstration of efficacious molecular targeting of angiogenic pathways in humans, support the further development of this technology to provide novel treatments which may be used as adjuncts or as superior alternatives to existing therapies.

Estilos ABNT, Harvard, Vancouver, APA, etc.

Tarroux, Francis. "Tentative d'induction d'un modele experimental animal de neo-vascularisation retinienne". Toulouse 3, 1988. http://www.theses.fr/1988TOU31317.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

CHAN, Kim Hoe. "Molecular and Cellular Determinants of Neovascularisation and Vascular Repair". Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/9889.

Texto completo da fonte

Resumo:

Cardiovascular disease remains the leading cause of death worldwide. However, there remain a significant number of patients who are not eligible for current treatment options. Therapeutic angiogenesis offer great potential in the treatment of cardiovascular disease. Recent experiments demonstrated that haem oxygenase-1 (Hmox1) possesses pro-angiogenic and atheroprotective properties. Recent studies have also shown that the vascular protective effects of Hmox1 may be mediated by endothelial progenitor cell (EPC) mobilisation. EPCs are implicated in vascular regeneration and angiogenesis. However, outcomes from clinical trials on cell therapy have been disappointing and hampered by the use of unselected cell populations. This thesis therefore investigated several aspects of the role of Hmox1 and EPCs in therapeutic angiogenesis and vascular repair. Firstly, the role of Hmox1 in ischaemia-mediated neovascularisation was investigated. Secondly, the relationship between bilirubin concentration (a surrogate marker of Hmox1 activity in humans) and amputation was explored. Thirdly, the relationship between level and function of distinct EPC populations and coronary collateralisation, as well as the extent of coronary epicardial and microvascular disease, was explored. There were several key findings from this thesis. Firstly, we found that Hmox1 played a critical role in ischaemia-mediated neovascularisation, and that this protective effect of Hmox1 may be mediated by EPC mobilisation and hypoxia-induced glucose metabolism. Secondly, we found an inverse relationship between bilirubin concentration and amputation. Lastly, we found that higher late-outgrowth endothelial cell, but not early EPC, levels and function were associated with better coronary collateralisation and less severe epicardial coronary disease. These findings may have implications for therapeutic angiogenesis and atheroprotection in the treatment of cardiovascular disease.

Estilos ABNT, Harvard, Vancouver, APA, etc.

GINESTE, CABARE MARIE-THERESE. "Les neovascularisations primitives et secondaires de la papille : a propos d'un cas". Toulouse 3, 1988. http://www.theses.fr/1988TOU31325.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

BRUNON, GUYONNET MICHELE. "Exophtalmies par neoformation vasculaire orbitaire". Saint-Etienne, 1989. http://www.theses.fr/1989STET6020.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

CALENDINI, ERIC. "Traitement du glaucome neovasculaire chez le diabetique". Nice, 1990. http://www.theses.fr/1990NICE6005.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

TAVERNIER, LEMAN ANNICK. "Les membranes neovasculaires choroidiennes chez l'enfant". Lille 2, 1990. http://www.theses.fr/1990LIL2M036.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Stone, Oliver Andrew. "On the origin of blood vessels : mechanisms of post-natal neovascularisation". Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520634.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

SALAMON, MAROUN. "Modeles experimentaux de decollement de retine tractionnel et de neovascularisation preretinienne". Nice, 1992. http://www.theses.fr/1992NICE6595.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Mais fontes

Livros sobre o assunto "Neovascularisation"

I, Moldovan Nicanor, ed. Novel angiogenic mechanisms: Role of circulating progenitor endothelial cells. New York: Kluwer Academic/Plenum, 2003.

Encontre o texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

International Workshop "Novel Angiogenic Mechanisms" (2002 Columbus, Ohio). Novel angiogenic mechanisms: Role of circulating progenitor endothelial cells. New York: Kluwer Academic/Plenum, 2003.

Encontre o texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

1935-, Epstein Stephen E., Kornowski Ran e Leon Martin B, eds. Handbook of myocardial revascularization and angiogenesis. London: Martin Dunitz, 2000.

Encontre o texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

M, Rabie A. Bakr, e Urist Marshall R, eds. Bone formation and repair: Proceedings of the International Symposium on Formation and Repair of Mineralized Extracellular Matrix, Hong Kong, 18-19 October, 1996. Amsterdam [Netherlands]: Elsevier, 1997.

Encontre o texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

(Editor), Matthias Clauss, e Georg Breier (Editor), eds. Mechanisms of Angiogenesis (Experientia Supplementum). Birkhäuser Basel, 2005.

Encontre o texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Leon, Martin B., Ran Kornowski e Stephen E. Epstein. Handbook of Myocardial Revascularization and Angiogenesis. Informa Healthcare, 1999.

Encontre o texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Kornowski, Ran, Martin B. Leon e Stephen E. Epstein. Handbook of Myocardial Revascularization and Angiogenesis. Taylor & Francis Group, 1999.

Encontre o texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Capítulos de livros sobre o assunto "Neovascularisation"

Lye, R. H., S. F. Elstow e J. B. Weiss. "Neovascularisation of intracranial tumours". In Biology of Brain Tumour, 61–66. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2297-9_8.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Bachmann, Björn, e Claus Cursiefen. "Immunomodulation Against Inflammatory Postkeratoplasty Neovascularisation". In Immune Modulation and Anti-Inflammatory Therapy in Ocular Disorders, 117–21. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-54350-0_7.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Rosen, Emanuel. "Refractive Lens Exchange and Choroidal Neovascularisation". In Management of Complications in Refractive Surgery, 315–20. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60561-6_34.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

van Eeden, Pauline E., Lisa Tee, Wei-Yong Shen, Sherralee Lukehurst, Chooi-May Lai, P. Elizabeth Rakoczy, Lyn D. Beazley e Sarah A. Dunlop. "Characterisation of a Model for Retinal Neovascularisation". In Retinal Degenerative Diseases, 163–68. Boston, MA: Springer US, 2006. http://dx.doi.org/10.1007/0-387-32442-9_24.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Reynolds, Alison L., David Kent e Breandán N. Kennedy. "Current and Emerging Therapies for Ocular Neovascularisation". In Retinal Degenerative Diseases, 797–804. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-3209-8_100.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Chakravarthy, Usha, e Susan B. Klein. "Radiation Biology of Choroidal Neovascularisation of Age-Related Macular Degeneration". In Age-Related Macular Degeneration, 79–83. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56439-0_9.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Garner, Alec, e Ralph Kissun. "The Role of Ischaemia in the Pathogenesis of Retinal Neovascularisation". In Documenta Ophthalmologica Proceedings Series, 131–34. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3337-8_19.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Manschot, W. A., W. R. Lee e G. E. Blass. "Development of Retinal Neovascularisation in Occlusive Retinal Vascular Disease in Adults". In Documenta Ophthalmologica Proceedings Series, 53–56. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3337-8_9.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Mörsdorf, P., A. Bächle, M. Amon, R. Schramm, F. Rezaeian, B. Vollmar, Y. Harder e M. D. Menger. "Simvastatin reduces ischemia-induced inflammation and stimulates neovascularisation of critically perfused flaps". In Deutsche Gesellschaft für Chirurgie, 281–83. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00625-8_104.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Chakravarthy, Usha. "External Beam Radiotherapy as a Treatment for Choroidal Neovascularisation in Age-Related Macular Degeneration". In Age-Related Macular Degeneration, 149–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56439-0_18.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Trabalhos de conferências sobre o assunto "Neovascularisation"

Frame, A. J. "Texture analysis of retinal neovascularisation". In IEE Colloquium on Pattern Recognition. IEE, 1997. http://dx.doi.org/10.1049/ic:19970128.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Brankin, E., P. McCullagh, W. Patton, A. Muldrew e N. Black. "Identification of Choroidal Neovascularisation on Fluorescein Angiograms Using Gradient Vector Flow Active Contours". In 2008 International Machine Vision and Image Processing Conference (IMVIP). IEEE, 2008. http://dx.doi.org/10.1109/imvip.2008.30.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Despott, EJ, A. Murino, N. Lazaridis, N. Koukias, A. Telese, Y. Hayashi e H. Yamamoto. "MUSCLE-RETRACTING SIGN WITH CONVERGENT NEOVASCULARISATION: AN OMINOUS FINDING AT ENDOSCOPIC SUBMUCOSAL DISSECTION". In ESGE Days 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1681363.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Padmasini, N., e R. Umamaheswari. "Detection of neovascularisation using K-means clustering through registration of peripapillary OCT and fundus retinal images". In 2016 IEEE International Conference on Computational Intelligence and Computing Research (ICCIC). IEEE, 2016. http://dx.doi.org/10.1109/iccic.2016.7919588.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Thomas, Tonia. "BS1 Investigating the role of endocardial notch signalling in neovascularisation of the heart after myocardial infarction". In British Cardiovascular Society Annual Conference ‘Digital Health Revolution’ 3–5 June 2019. BMJ Publishing Group Ltd and British Cardiovascular Society, 2019. http://dx.doi.org/10.1136/heartjnl-2019-bcs.165.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Lewis, Christopher TA, Keith S. Mascall, Heather M. Wilson, Gary R. Small, Keith M. Kerr, George Gibson e Graeme F. Nixon. "3M03 Soluble fms-like tyrosine kinase 1 (sFlt1) is downregulated in aortic valve stenosis, promoting intravalvular neovascularisation". In The Scottish Cardiovascular Forum 2019, Saturday 2nd February 2019, The Centre for Health Science, Old Perth Road, Inverness, Scotland. BMJ Publishing Group Ltd and British Cardiovascular Society, 2019. http://dx.doi.org/10.1136/heartjnl-2019-scf.3.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Szabo, T. "FRAGMENTATION OF CERULOPLASMIN BY THROMBINF". In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644663.

Texto completo da fonte

Resumo:

Copper containing proteolytic fragments of ceruloplasmin (CP), a 135 KDα2 -glycoprotein, have been shown to induce angiogenesis in the rabbit cornea assay.Neovascularisation plays an important role in different biological phenomena including chronic inflammation, wound healing, recanalisation of occluded blood vessels, tumor growth etc. Most of these events are associated with elevated CP levels. Neovascularisation occurs in diabetic macro- and microangiopathies as well. Serum CP concentrations in 92 diabetics were measured and compored to 50 healthy blood donors and 50 unselected hospitalized patients without malignancies. A marked CP elevation was observed in diabetics, especially in those with vascular complications. There was no correlation between the CP and the actual blood glucose concentrations, duration of the disease of the type of the treatment. Activation of the haemostatic processes has been found in the majority of diabetic patients with vascular diseases. In case CP is a substrate for thrombin, the generation of this specific serine protease may lead to the release of angiogenic peptides from CP on the site of vascular occlusion. For this reason, purified human CP was incubated with thrombin at pH 7.4, 37×C, and samples were removed at 0, 30, 60, 120, 240, min., and\after 2k hours for CP oxidase activity measurements and for SDS PAGE. Thrombin treatment did not affect the enzymic activity of CP. On SDS PAGE the band corresponding to the parent molecule eventually disappeared, and a Mr ll6 KD fragment together with three smaller peptides has been produced, with molecular masses 61, 4l and 20 KD, respectively. Based on these experiments, CP is to be considered as a new protein substrate for thrombin. The physiological relevance of this phenomenon needs further examination.

Estilos ABNT, Harvard, Vancouver, APA, etc.

Patel, Yash, Prajakta Belekar, Bernhard Baumann e Conrad W. Merkle. "Blood flow analysis of retinal neovascularisations in a VLDLR mouse model using contrast-enhanced optical coherence tomography". In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, editado por Joseph A. Izatt e James G. Fujimoto. SPIE, 2024. http://dx.doi.org/10.1117/12.3005666.

Texto completo da fonte

Estilos ABNT, Harvard, Vancouver, APA, etc.

Oferecemos descontos em todos os planos premium para autores cujas obras estão incluídas em seleções literárias temáticas. Contate-nos para obter um código promocional único!