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Artigos de revistas sobre o assunto "Nano-Theranostics"

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Liu, Zhuang, e Xing-Jie Liang. "Nano-Carbons as Theranostics". Theranostics 2, n.º 3 (2012): 235–37. http://dx.doi.org/10.7150/thno.4156.

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Yoon, Juyoung. "Theranostics based nano probes and nano carriers". Coordination Chemistry Reviews 415 (julho de 2020): 213297. http://dx.doi.org/10.1016/j.ccr.2020.213297.

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Sharmiladevi, Palani, Koyeli Girigoswami, Viswanathan Haribabu e Agnishwar Girigoswami. "Nano-enabled theranostics for cancer". Materials Advances 2, n.º 9 (2021): 2876–91. http://dx.doi.org/10.1039/d1ma00069a.

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The review highlights the nanotheranostic agents prove to be highly efficient in generating theragnosis overcoming the deficiencies noted with conventional diagnostic and therapeutic agents used for cancers.
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Kalita, Himani, e Manoj Patowary. "Biocompatible Polymer Nano-Constructs: A Potent Platform for Cancer Theranostics". Technology in Cancer Research & Treatment 22 (janeiro de 2023): 153303382311603. http://dx.doi.org/10.1177/15330338231160391.

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Nano-constructs of biocompatible polymers have drawn wide attention owing to their potential as theranostics for simultaneous therapy and detection of cancer. The present mini review summarizes various nano-architectures of polymers that have been developed as theranostic agents for the simultaneous treatment and diagnosis of cancer in a single platform. Additionally, research prospects of polymeric cancer theranostics for the future have been highlighted.
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Lee, Songyi, Thanh Chung Pham, Chaeeon Bae, Yeonghwan Choi, Yong Kyun Kim e Juyoung Yoon. "Nano theranostics platforms that utilize proteins". Coordination Chemistry Reviews 412 (junho de 2020): 213258. http://dx.doi.org/10.1016/j.ccr.2020.213258.

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Wang, Yong-Mei, Ying Xu, Xinxin Zhang, Yifan Cui, Qingquan Liang, Cunshun Liu, Xinan Wang, Shuqi Wu e Rusen Yang. "Single Nano-Sized Metal–Organic Framework for Bio-Nanoarchitectonics with In Vivo Fluorescence Imaging and Chemo-Photodynamic Therapy". Nanomaterials 12, n.º 2 (17 de janeiro de 2022): 287. http://dx.doi.org/10.3390/nano12020287.

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Theranostics is an emerging technique for cancer treatments due to its safety and high efficiency. However, the stability, efficiency, and convenience of preparation are the main challenges for developing theranostics. Here we describe a one-pot process for biocompatible metal–organic framework (MOF)-based theranostics. The ligand H2L designed for the MOF enables both red fluorescence emission and photodynamic therapy (PDT). The frame and regular channel structure of H2L-MOF empower the theranostics with good drug delivery performance, and the uniform and nano-sized particles facilitate the in vivo imaging/therapy applications. In vivo fluorescence imaging and in vitro chemo-photodynamic therapy were achieved with the MOF without any further modification. Our results reveal an effective strategy to achieve multifunctional theranostics by the synergistic action of the organic ligand, metal node, and channel structure of MOF nanoparticles.
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Sneider, Alexandra, Derek VanDyke, Shailee Paliwal e Prakash Rai. "Remotely Triggered Nano-Theranostics For Cancer Applications". Nanotheranostics 1, n.º 1 (2017): 1–22. http://dx.doi.org/10.7150/ntno.17109.

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Yao, Jingwen, Chao-Hsiung Hsu, Zhao Li, Tanya Kim, Lian-Pin Hwang, Ying-Chih Lin e Yung-Ya Lin. "Magnetic Resonance Nano-Theranostics for Glioblastoma Multiforme". Current Pharmaceutical Design 21, n.º 36 (2 de novembro de 2015): 5256–66. http://dx.doi.org/10.2174/1381612821666150923103307.

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Mousavi, Hajar, Behrooz Movahedi, Ali Zarrabi e Marzieh Jahandar. "A multifunctional hierarchically assembled magnetic nanostructure towards cancer nano-theranostics". RSC Advances 5, n.º 94 (2015): 77255–63. http://dx.doi.org/10.1039/c5ra16776k.

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Dai, Yan-Dong, Xue-Yi Sun, Wan Sun, Jing-Bo Yang, Rui Liu, Yi Luo, Tao Zhang, Yu Tian, Zhong-Lin Lu e Lan He. "H2O2-responsive polymeric micelles with a benzil moiety for efficient DOX delivery and AIE imaging". Organic & Biomolecular Chemistry 17, n.º 22 (2019): 5570–77. http://dx.doi.org/10.1039/c9ob00859d.

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Teses / dissertações sobre o assunto "Nano-Theranostics"

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Maturi, Mirko <1993&gt. "Advanced Functional Organic-Inorganic Hybrid (Nano)Materials: from Theranostics to Organic Electronics and Additive Manufacturing". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amsdottorato.unibo.it/9739/1/Maturi_Mirko_tesi.pdf.

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This work is going to show the activities performed in the frame of my PhD studies at the University of Bologna, under the supervision of Prof. Mauro Comes Franchini, at the Department of Industrial Chemistry “Toso Montanari”. The main topic of this dissertation will be the study of organic-inorganic hybrid nanostructures and materials for advanced applications in different fields of materials technology and development such as theranostics, organic electronics and additive manufacturing, also known as 3D printing. This work is therefore divided into three chapters, that recall the fundamentals of each subject and to recap the state-of-the-art of scientific research around each topic. In each chapter, the published works and preliminary results obtained during my PhD career will be discussed in detail.
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Perecin, Caio José. "Nanopartículas superparamagnéticas encapsuladas com polímeros para tratamento de câncer por hipertermia". Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/82/82131/tde-22062016-103823/.

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O câncer é uma das maiores causas de mortalidade no Brasil e no mundo, com potencial de crescimento nas próximas décadas. Um tipo de tratamento promissor é a hipertermia magnética, procedimento no qual as células tumorais morrem pelo efeito do calor gerado por partículas magnéticas após a aplicação de campo magnético alternado em frequências adequadas. Tais partículas também são capazes de atuar como agentes de contraste para imageamento por ressonância magnética, um poderoso método de diagnóstico para identificação de células neoplásicas, formando a combinação conhecida como theranostics (terapia e diagnóstico). Neste trabalho foram sintetizadas nanopartículas de óxido de ferro por método de coprecipitação com posterior encapsulação por técnica de nano spray drying, visando sua aplicação no tratamento de câncer por hipertermia e como agente de contraste para imageamento por ressonância magnética. Para a encapsulação foram utilizadas matrizes poliméricas de Maltodextrina com Polissorbato 80, Pluronic F68, Eudragit® S100 e PCL com Pluronic F68, escolhidos com o intuito de formar partículas que dispersem bem em meio aquoso e que consigam atingir alvo tumoral após administração no corpo do paciente. Parâmetros de secagem pelo equipamento Nano Spray Dryer, como temperatura, solvente e concentração de reagentes, foram avaliados. As partículas formadas foram caracterizadas por Microscopia Eletrônica de Varredura, Difração de Raios-X, Análise Termogravimétrica, Espalhamento de Luz Dinâmico, Espectroscopia de Infravermelho, magnetismo quanto a magnetização de saturação e temperatura, citotoxicidade e potencial de aquecimento. Tais procedimentos indicaram que o método de coprecipitação produziu nanopartículas de magnetita de tamanho em torno 20 nm, superparamagnéticas a temperatura ambiente, sem potencial citotóxico. A técnica de nano spray drying foi eficiente para a formação de partículas com tamanho em torno de 1 μm, também superparamagnéticas, biocompatíveis e com propriedades magnéticas adequadas e para aplicações pretendidas. Destaca-se a amostra com Pluronic, OF-10/15-1P, que apresentou magnetização de saturação de 68,7 emu/g e interação específica com células tumorais.
Cancer is one of the greatest causes of mortality in Brazil and in the world, with growing potential for the next decades. A promising treatment alternative is magnetic hyperthermia, in which tumor cells die by the heat generated by magnetic nanoparticles after application of an alternate magnetic field in adequate frequencies. Such particles are also capable of acting as contrast agents for magnetic resonance imaging, a powerful method of diagnosis for the identification of neoplasic cells, which characterizes the combination of properties known as theranostics (therapy and diagnosis). In this work, iron oxide nanoparticles were synthesized by coprecipitation method with subsequent encapsulation by nano spray drying technique, aiming their application on cancer treatment by hyperthermia and on magnetic resonance imaging as a contrast agent. Polymeric matrices of Maltodextrin with Polysorbate 80, Pluronic F68, Eudragit® S100 and PCL with Pluronic F68 were employed for encapsulation, chosen carefully to create particles that disperse well in aqueous media and that are able to address the tumoral target after administration into the patient\'s body. Drying parameters of the Nano Spray Dryer equipment, such as temperature, dispersing medium and reagent concentrations, were evaluated. The generated particles were characterized by Scanning Electron Microscopy, X-Ray Diffraction, Thermogravimetric Analysis, Dynamic Light Scattering, Infrared Spectroscopy, by magnetism in matters of applied magnetic field and temperature, cytotoxic potential and heating potential. Such methods indicated that the coprecipitation method was able to produce magnetite nanoparticles with size of approximately 20 nm, superparamagnetic at room temperature and with no cytotoxic potential. The nano spray drying technique was efficient to produce particles with size of around 1 μm, biocompatible, superparamagnetic and with adequate magnetic properties for the intended applications. The sample OF-10/15-1P stands out with a saturation magnetization of 68.7 emu/g and presenting specific interactions with the tumour cells.
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Alaouta, Cherine. "Imagerie moléculaire pour la nano-théranostique : approche par spectroscopie Raman". Electronic Thesis or Diss., Reims, 2024. http://www.theses.fr/2024REIMP201.

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Bien que le traitement du cancer ait fait des progrès considérables, la résistance aux thérapies anticancéreuses demeure une cause majeure d'échec thérapeutique. Une approche pour relever ce défi est la squalénisation des médicaments, une méthode qui consiste à lier covalemment le squalène à des composés pharmaceutiques actifs, générant ainsi de puissants agents anticancéreux dotés de capacités d'auto-assemblage. Dans cette étude, la microspectroscopie Raman a été utilisée pour examiner les effets des médicaments anticancéreux Gem et DXF, ainsi que des nanoparticules squalénisées (GemSQ non-déutérée et déutérée, et SQDXF), sur des lignées cellulaires de carcinome mammaire (MCF7 et MDA-MB-231) et de carcinome colique (HT-29 et HCT-116).Gem et DXF présentent tous deux de faibles sections efficaces Raman, ce qui rend leur détection difficile à des concentrations physiologiques en raison de leurs structures analogues nucléosidiques et de leur faible rendement quantique en fluorescence. Pour améliorer la détectabilité de Gem, celui-ci a été conjugué avec de l’acide squalénique déutéré, produisant un analogue avec une signature spectrale distincte dans la plage des 2000-2300 cm⁻¹, sans interférence avec les molécules endogènes des cellules. Cependant, cette stratégie n'était pas faisable pour DXF, et la détection des nanoparticules SQDXF a donc été réalisée en surveillant leurs effets au niveau subcellulaire.Les résultats ont fourni des informations précieuses sur les interactions entre les médicaments et les principaux composants cellulaires tels que l'ADN, l'ARN, les protéines et les lipides, ces observations étant liées aux effets cytotoxiques des composés. Cette recherche ouvre de nouvelles perspectives prometteuses dans le domaine de la nanomédecine
Although cancer treatment has seen considerable progress, resistance to anticancer therapies remains a major cause of treatment failure. One approach to address this challenge is drug squalenization, a method that involves covalently attaching squalene to active pharmaceutical compounds, thereby generating powerful anticancer agents with self-assembly capabilities. In this study, Raman microspectroscopy was utilized to investigate the effects of the anticancer drugs Gem and DXF, along with squalenized nanoparticles (non-deuterated and deuterated GemSQ, and SQDXF), on breast carcinoma cell lines (MCF7 and MDA-MB-231) and colon carcinoma cell lines (HT-29 and HCT-116).Both Gem and DXF exhibit weak Raman cross sections, making them difficult to detect using Raman spectroscopy at physiological concentrations due to their nucleoside-analogue structures and low fluorescence quantum yield. To enhance the detectability of Gem, it was conjugated with deuterated squalenic acid, producing an analogue with a distinct spectral signature in the 2000-2300 cm⁻¹ range, free from interference by endogenous cell molecules. However, this strategy was not feasible for DXF, and the detection of SQDXF nanoparticles was instead achieved by monitoring their subcellular effects.The results provided valuable insights into the interactions between the drugs and key cellular components such as DNA, RNA, proteins, and lipids, with the findings being linked to the cytotoxic effects of the compounds. This research opens up promising new avenues in nanomedicine
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Wu, Linxi. "The impact of nanoconjugation to EGF-induced apoptosis". Thesis, 2016. https://hdl.handle.net/2144/14555.

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Engineered nanoparticles provide potential opportunities for improving current drug delivery, bioimaging and biosensing modalities. In many cases, a ligand, such as a protein, peptide or nucleic acids, is attached to the nanoparticles surface to serve as a targeting group. However, the nanoconjugation (i.e. covalently bound molecules to a nanocarrier) is not an innocuous reaction. It can change the binding affinity and interfere with the intracellular trafficking of the tethered species. The understanding of this influence to the tethered species is still lacking. Therefore, the main objective of this thesis is to investigate the effect of nanoconjugation to the biological identity of the tethered biomolecules, in terms of cellular uptake, intracellular trafficking and the ultimate biological outcomes. The Epidermal Growth Factor Receptor (EGFR) is a tyrosine kinase that regulates cell proliferation and can cause cancer if dysregulated. Continuous treatment with high doses of EGF can induce apoptosis, in EGFR overexpressing cell lines. In this thesis, Epidermal Growth Factor (EGF) was chosen as the object of investigation. Covalent attachment of EGF to gold nanoparticles (NP-EGF) was found to enhance apoptosis in EGFR overexpressing cell lines (A431, MDA-MB-468) and it is sufficient to induce apoptosis in cell lines exhibiting EGFR expression at physiological levels (HeLa). NP-EGF accumulation through the endosomal pathway was also investigated to assess the impact of nanoconjugation on the spatio-temporal distribution of NP-EGF as potential origin for the observed enhancement of apoptosis. Two orthogonal experimental approaches were applied: (1) isolation of NP-EGF containing endosomes by taking advantage of the increased density of endosomes associated with the uptake of Au NPs; (2) correlated darkfield/fluorescence imaging to map the spatial distribution of NP-EGF in endosomes as a function of time. The studies reveal that nanoconjugation prolongs the dwelling time of phosphorylated receptors in the early endosomes and that the retention of activated EGFR in the early endosomes is accompanied by an EGF mediated apoptosis at effective concentrations that do not induce apoptosis in the case of the free EGF. Investigating the nanoconjugation-enhanced EGF-induced apoptosis improves the current understanding of cell-nanomatieral interactions and provides new opportunities for overcoming apoptosis evasion by cancer cells.
2017-01-01T00:00:00Z
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Livros sobre o assunto "Nano-Theranostics"

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Zarepour, Atefeh, Ali Zarrabi e Arezoo Khosravi. SPIONs as Nano-Theranostics Agents. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3563-0.

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Nano-Pharmacokinetics and Theranostics. Elsevier, 2021. http://dx.doi.org/10.1016/c2020-0-02014-1.

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Liu, Qing, e Donglu Shi. Tissue Engineering and Nano Theranostics. World Scientific Publishing Co Pte Ltd, 2017.

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Zarepour, Atefeh, Ali Zarrabi e Arezoo Khosravi. SPIONs as Nano-Theranostics Agents. Springer, 2017.

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Zarepour, Atefeh, Ali Zarrabi e Arezoo Khosravi. SPIONs as Nano-Theranostics Agents. Springer, 2017.

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Thorat, Nanasaheb D., e Nitesh Kumar. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy. Elsevier Science & Technology Books, 2021.

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Capítulos de livros sobre o assunto "Nano-Theranostics"

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Zarepour, Atefeh, Ali Zarrabi e Arezoo Khosravi. "SPIONs as Nano-Theranostics Agents". In SPIONs as Nano-Theranostics Agents, 1–44. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3563-0_1.

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Ichiyanagi, Yuko. "Magnetic Nanoparticles for Diagnostics and Therapy". In Extracellular Fine Particles, 261–73. Singapore: Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-97-7067-0_18.

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Abstract Magnetic materials have long been essential to human life. Nanometer-sized magnetic particles have recently attracted attention for the development of magnetic materials, such as electronic devices, and other fields such as medicine. Here, we introduce the development of nanosized magnetic particles produced using our unique manufacturing method for biomedical applications. We discuss the possibility of cancer thermotherapy using magnetic nanoparticles (MNPs) for therapeutic applications and magnetic resonance imaging for diagnostic applications. We expect a trend toward nano-theranostics in which MNPs can simultaneously be used for treatment and diagnosis.
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Jain, Kopal, Nikita Basant e Amit Panwar. "New Developments in Nano-theranostics Combined with Intelligent Bio-responsive Systems". In Smart Nanomaterials Targeting Pathological Hypoxia, 347–65. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-1718-1_18.

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Saini, Neha, Prem Pandey, Mandar Shirolkar, Atul Kulkarni, Sang-Hyun Moh e Anjali A. Kulkarni. "Role of Carbon Nanostructures as Nano-Theranostics Against Breast and Brain Cancer". In Materials Horizons: From Nature to Nanomaterials, 1151–72. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-7188-4_41.

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Fatima, Syeda Warisul, Shahenvaz Alam e Sunil K. Khare. "Janus Nano-Assembly Based Sensing Platform for Cancer Theranostics: An Unrivaled Mastering Bioimaging Perspective". In Nanoscale Sensors and their Applications in Biomedical Imaging, 225–49. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-3144-2_14.

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Pham, Tuan, Carl Beigie, Yoonjee Park e Joyce Y. Wong. "Microbubbles as Theranostics Agents". In Nano-Oncologicals, 329–50. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-08084-0_12.

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Singh, Gagandeep, L. Preethi e Neelam Thakur. "Nano–Bio Dynamics". In Nanoparticles in Cancer Theranostics, 53–68. Boca Raton: CRC Press, 2024. http://dx.doi.org/10.1201/9781003463191-4.

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Singh, Gagandeep, Arshiya Sood e Neelam Thakur. "Nano Contrast Agents". In Nanoparticles in Cancer Theranostics, 110–22. Boca Raton: CRC Press, 2024. http://dx.doi.org/10.1201/9781003463191-8.

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Conde, João, Furong Tian, Pedro V. Baptista e Jesús M. de la Fuente. "Multifunctional Gold Nanocarriers for Cancer Theranostics: From Bench to Bedside and Back Again?" In Nano-Oncologicals, 295–328. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-08084-0_11.

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Parihar, Vipan Kumar. "Nano-pharmacokinetics and cancer theranostics". In Nano-Pharmacokinetics and Theranostics, 221–32. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-323-85050-6.00014-1.

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Trabalhos de conferências sobre o assunto "Nano-Theranostics"

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Delehanty, James B., Juan B. Blanco-Canosa, Christopher E. Bradburne, Kimihiro Susumu, Michael H. Stewart, Duane E. Prasuhn, Philip E. Dawson e Igor L. Medintz. "Controlling the intracellular fate of nano-bioconjugates: pathways for realizing nanoparticle-mediated theranostics". In SPIE NanoScience + Engineering, editado por Hooman Mohseni, Massoud H. Agahi e Manijeh Razeghi. SPIE, 2014. http://dx.doi.org/10.1117/12.2064372.

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Suttee, Ashish, e Prashant Tandale. "Graphene oxide based multifunctional nano composite for cancer theranostics: Present clinical and regulatory breakthroughs". In THE FOURTH SCIENTIFIC CONFERENCE FOR ELECTRICAL ENGINEERING TECHNIQUES RESEARCH (EETR2022). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0162990.

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Goswami, Mayank, Xinlei Wang, Pengfei Zhang, Wenwu Xiao, Kit S. Lam, Edward N. Pugh e Robert J. Zawadzki. "Methods for non-surgical cancer nano-theranostics of ocular tumors in the mouse eye (Conference Presentation)". In Ophthalmic Technologies XXVII, editado por Fabrice Manns, Per G. Söderberg e Arthur Ho. SPIE, 2017. http://dx.doi.org/10.1117/12.2251803.

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Lodi, Matteo B. "A Preliminary Propagation Study on Magnetic Scaffolds for Microwave Theranostics". In 2023 IEEE 23rd International Conference on Nanotechnology (NANO). IEEE, 2023. http://dx.doi.org/10.1109/nano58406.2023.10231176.

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Chauhan, Deepak Singh, e Rohit Srivastava. "Synthesis and characterization of gold encapsulated and tamoxifen loaded PLGA nanoparticles for breast cancer theranostics". In 2015 9th IEEE International Conference on Nano/Molecular Medicine & Engineering (NANOMED). IEEE, 2015. http://dx.doi.org/10.1109/nanomed.2015.7492510.

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Relatórios de organizações sobre o assunto "Nano-Theranostics"

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Tantsyrev, Anatoliy, Yuliya Titova e Andrey Ivanov. Polysaccharide macromolecules as transport matrices of nano-size compositions, candidates for diagnostics, therapy and theranostics of cancer diseases. Peeref, junho de 2023. http://dx.doi.org/10.54985/peeref.2306p9855801.

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