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Artigos de revistas sobre o assunto "N6494"
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Pedrosa, José Manuel. "“El golpe matador, el golpe resucitador: la herida épica y su antídoto mágico”". Nueva Revista de Filología Hispánica (NRFH) 60, n.º 1 (1 de janeiro de 2012): 75. http://dx.doi.org/10.24201/nrfh.v60i1.1088.
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Fecha de recepción:8 de diciembre de 2011. Fecha de aceptación:10 de febrero de 2012. Análisis de los motivos folclóricos internacionales C742, C742.1 y E 1 1 . 1 ,que pueden resumirse así: el primer golpe que el humano da a un monstruo le hiere gravemente, pero el segundo golpe le cura o le resucita. Estudio de su relación con los motivos N642, N642.1 y N644, que pueden resumirse así: un golpe cura de manera casual una enfermedad previa. Revisión de leyendas, cuentos, creencias, supersticiones y romances que incorporan estos motivos, desde los Mabinogion galeses y Las mil y una noches hasta diversas leyendas modernas españolas, árabes e internacionales, o la novela El guardián entre el centeno, de Salinger.
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Mironova, E. S., N. Yu Mironov, N. A. Mironova, Peter Sergeevich Novikov, I. A. Novikov, Lada Yurievna Layovich, Evgeny Borisovich Maykov e Sergey Pavlovich Golitsyn. "Electrophysiological Cardiac Parameters and Results of Antiarrhythmic Treatment in Patients with Paroxysmal Atrial Fibrillation (Lone and Associated with Arterial Hypertension)". Kardiologiia 59, n.º 8 (8 de agosto de 2019): 39–46. http://dx.doi.org/10.18087/cardio.2019.8.n644.
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Purpose: to assess cardiac electrophysiological parameters in patients with paroxysmal atrial fibrillation (AF), lone or with concomitant arterial hypertension (AH), and their prognostic significance relative to treatment effectiveness.Materials and methods. We included in this study 184 patients with paroxysmal AF (84 with concomitant AH and 100 with presumed lone AF). Cardiac electrophysiological study was performed in accordance with standardized protocol that included assessment of sinus node recovery time, sinoatrial, intraatrial and interatrial conduction time, and effective refractory periods (ERP) of right and left atria and atrioventricular node. Patients with inducible supraventricular reentrant arrhythmias that could potentially trigger AF underwent catheter radiofrequency ablation of those arrhythmias. Other patients received either antiarrhythmic drug therapy (AAD; n=79) or catheter cryo-ablation (CBA; n=81). Treatment was considered ineffective in case of any symptomatic or asymptomatic AF episode documented by ECG or Holter ECG within 12 months of follow-up.Results. Patients with lone AF compared with those with AH had shorter ERP of the right atrium (219±21 ms vs. 253±44 ms, respectively, p<0.05) and more prominent dispersion of ERP of right and left atria (median 40 ms, interquartile range 10-50 ms vs. median 20 ms, interquartile range 10-22.5 ms, respectively, p<0.05). There was no statistically significant difference in other electrophysiology parameters between the groups. Sustained supraventricular reentrant arrhythmias were induced in 9% (9 of 100) patients with presumed lone AF and in 1.2% (1 of 84) patients with AH (p<0.05). All these arrhythmias were successfully ablated, and patients had no AF recurrence during 12-month follow-up. Among other patient treatment (CBA n=81, AAD n=79) was effective in 64% of those with lone AFib and in 34% - with AH (p<0.05). In multivariate multiple regression analysis, none of electrophysiological parameters could be assumed as a factor associated with the efficacy of CBA or AAD. Conclusion. Patients with lone AF had more prominent atrial electrophysiological inhomogeneity compared with patients with concomitant AH. Cardiac electrophysiological parameters had no influence on effectiveness of antiarrhythmic treatment.
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Глазунова, И. Н. "Features of the use of gaming technologies in pre-school education institutions". Management of Education 14, n.º 1-2(75) (30 de janeiro de 2024): 98–105. http://dx.doi.org/10.25726/n6944-9867-1377-m.
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В статье исследуются особенности применения игровых технологий в повседневной образовательной практике дошкольных учреждений. Автором предпринята попытка обобщить имеющийся в настоящее время опыт использования различных форм игрового взаимодействия между педагогами и воспитанниками в целях максимизации эффективности образовательного процесса. Во вводной части уделено внимание теоретическим основам роли игры в развитии ребенка раннего возраста и становлении его личности. Приводятся данные о спектре игровых методик, которые целесообразно включать в повседневную работу с детьми дошкольного возраста. В разделе о материалах и методах исследования описаны конкретные примеры использования игровых элементов по разным направлениям в восьми московских детских садах численностью более 250 человек каждый. В результативной части проведен сравнительный анализ эффективности различных подходов к организации игрового процесса, основанный на педагогическом наблюдении и тестировании. Сделан вывод о высокой степени влияния качественно построенных игровых занятий на развитие познавательных, коммуникативных и личностных качеств воспитанников. The article examines the features of the use of gaming technologies in the daily educational practice of preschool institutions. The author attempts to summarize the currently available experience of using various forms of game interaction between teachers and students in order to maximize the effectiveness of the educational process. In the introductory part, attention is paid to the theoretical foundations of the role of play in the development of an early child and the formation of his personality. The data on the range of game techniques that it is advisable to include in daily work with preschool children are presented. The section on materials and research methods describes specific examples of the use of game elements in various directions in eight Moscow kindergartens with more than 250 people each. In the effective part, a comparative analysis of the effectiveness of various approaches to the organization of the gameplay, based on pedagogical observation and testing, is carried out. The conclusion is made about the high degree of influence of qualitatively constructed play activities on the development of cognitive, communicative and personal qualities of pupils.
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Wakabayashi, Hironao, e Philip J. Fay. "Localization of Factor VIII Residues Contributing to Factor VIII and/or VIIIa Structural Stability as Detected by Rates of Activity Decay." Blood 110, n.º 11 (16 de novembro de 2007): 1763. http://dx.doi.org/10.1182/blood.v110.11.1763.1763.
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Abstract Factor VIII circulates as a heterodimer composed of a heavy chain and light chain. Thrombin converts factor VIII into the active cofactor, factor VIIIa, by cleaving heavy chain into A1 and A2 subunits. While the A1 subunit maintains a stable interaction with the light chain-derived A3C1C2 subunit, the A2 subunit is weakly associated in the trimer and this low affinity interaction accounts for the instability of factor VIIIa activity. In examining the ceruloplasmin-based factor VIII A domain model, potential hydrogen bond pairings based upon spatial separations of <2.8Å were found between side chains of the A2 domain residues and residues in the A1 or A3 domain represented by residues D27, R282, E287, D302, S313, H317, Y476, T522, R531, N538, E540, S650, Y664, N684, N694, S695, D696, Y1786, S1791, Y1792, D1795, E1829, and S1949. Since hydrogen bonds at an interactive site contribute to structural stability, we performed a scanning mutagenesis study where these residues were individually replaced with Ala, except Tyr residues were replaced with Phe, in order to examine the contribution of each site to the stability of the factor VIII/VIIIa forms. Factor VIII activity decay was followed by incubating factor VIII (5 nM) at 55°C, and at indicated times removing an aliquot, activating with thrombin and measuring residual activity by a factor Xa generation assay. Factor VIIIa activity decay was measured by mixing factor VIII (5 nM) with factor IXa (40 nM), activating factor VIII with thrombin, and following factor Xase activity at 23°C by factor Xa generation. Non-linear least squares regression using a single exponential decay equation of activity versus time was performed to obtain rates for factor VIII/VIIIa activity decay. Eleven out of 23 factor VIII mutants showed increases in either or both decay rates by >2-fold compared to wild type (WT) (Figure). Of these mutants, R282A showed the largest increase in both factor VIII and VIIIa decay rates (∼30-fold compared to WT). Interestingly, 5 mutants (T522A, D1795A, Y1792F, Y1786F, and E1892A) showed >2-fold increased rates in factor VIIIa decay compared with the rates for factor VIII decay, whereas 2 mutants (N694A and Y664F) showed >2-fold increased rates in factor VIII decay compared with rates for factor VIIIa decay. These results suggest that several residues at the A1-A2 and A2-A3 domain interfaces contribute to stabilizing the protein through hydrogen bonding and that mutation at these sites result in loss of stability as determined by enhanced rates of activity decay. Furthermore, these results permit discrimination between stabilizing hydrogen bonding in the procofactor from active cofactor, where bonding in the latter appears to make a more significant contribution to stability. This observation is consistent with an altered conformation involving new inter-subunit interactions for the A2 domain following factor VIII activation. Factor VIII/FVIIIa Decay Rate Factor VIII/FVIIIa Decay Rate
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Idowu, Abel O., Wellington A. Oyibo, Sanjib Bhattacharyya, Manjeet Khubbar, Udoma E. Mendie, Violet V. Bumah, Carolyn Black, Joseph Igietseme e Anthony A. Azenabor. "Rare mutations in Pfmdr1 gene of Plasmodium falciparum detected in clinical isolates from patients treated with anti-malarial drug in Nigeria". Malaria Journal 18, n.º 1 (18 de setembro de 2019). http://dx.doi.org/10.1186/s12936-019-2947-z.
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Abstract Background Plasmodium falciparum, the deadliest causative agent of malaria, has high prevalence in Nigeria. Drug resistance causing failure of previously effective drugs has compromised anti-malarial treatment. On this basis, there is need for a proactive surveillance for resistance markers to the currently recommended artemisinin-based combination therapy (ACT), for early detection of resistance before it become widespread. Methods This study assessed anti-malarial resistance genes polymorphism in patients with uncomplicated P. falciparum malaria in Lagos, Nigeria. Sanger and Next Generation Sequencing (NGS) methods were used to screen for mutations in thirty-seven malaria positive blood samples targeting the P. falciparum chloroquine-resistance transporter (Pfcrt), P. falciparum multidrug-resistance 1 (Pfmdr1), and P. falciparum kelch 13 (Pfk13) genes, which have been previously associated with anti-malarial resistance. Results Expectedly, the NGS method was more proficient, detecting six Pfmdr1, seven Pfcrt and three Pfk13 mutations in the studied clinical isolates from Nigeria, a malaria endemic area. These mutations included rare Pfmdr1 mutations, N504K, N649D, F938Y and S967N, which were previously unreported. In addition, there was moderate prevalence of the K76T mutation (34.6%) associated with chloroquine and amodiaquine resistance, and high prevalence of the N86 wild type allele (92.3%) associated with lumefantrine resistance. Conclusion Widespread circulation of mutations associated with resistance to current anti-malarial drugs could potentially limit effective malaria therapy in endemic populations.
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Costa, H., R. Fernandes, T. Mota, J. Bispo, P. Azevedo, M. Santo, D. Carvalho, N. Marques, R. Candeias e I. Jesus. "S-reflex score: a predictor score of vaso-vagal reflex syncope". European Heart Journal. Acute Cardiovascular Care 10, Supplement_1 (1 de abril de 2021). http://dx.doi.org/10.1093/ehjacc/zuab020.016.
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Abstract Funding Acknowledgements Type of funding sources: None. Introduction Reflex syncope is one of the most common causes of syncope, usually associated with unspecified triggers and prodromes. The probability of occurrence is higher when concomitant factors coexist whether inherent to individual or related to environment, and changes in conventional tests may prove useful in their diagnosis. Objective Identify predictive factors in the initial investigation in order to establish a predictor score of vasovagal reflex syncope (VVS). Methods Observational and retrospective study, with descriptive analysis and correlation of patients followed in syncope appointment at a Cardiology Center from 1 January 2015 to 31 Novembe 2019. Descriptive analysis on patient characteristics and complementary exams were carried out. The correlation test used between categorical variables was Chi-square and among continuous variables the T-Student test with a significance level of 95%. Independent predictors of VVS were identified through binary logistic regression considering a p = 0.05, with subsequent application of a discriminatory function using the lambda Wilks test to determine the discriminant score of variables under analysis. SPSS 24.0 was used for statistical analysis. Results Identified N694 patients, 52% male, mean age of 63 years. 15.7% of patients with suspected VVS in a first impression. At the end, 22.9% diagnosed with VVS and of these 66% had syncope recurrence. 42% had long prodromes (p = 0.013), 17% with heat prodromes (p = 0.012), in 11.3% the trigger was the meal (p = 0.031), 12.2% suffered trauma (p = 0.07) and 59.7% had ECG with pathological q wave (p = 0.00), thus showing to be independet predictors of VVS. A predictor score of VVS was determined using the formula = -0.761 + (0.529.Long_Prodromes) + (0.721.Heat_Prodromes) + (0.313.Trigger_Meal) + (2,431.ECG_q) - (0.542.Trauma), with a cutoff value of 0.258, specificity of 90.5% with discriminative power of 87%. Conclusion The final diagnosis of VVS was higher than suspicions during initial clinical investigation and 66% of these patients had recurrence. The independent predictors factors of VVS are long prodromes, heat prodromes, meal as a trigger, ECG with q waves and trauma. The S-Reflex score was determined with a good discriminative power with high specificity. Considering clinical variables and conventional exams, this score could be useful to guide the strategy for syncope patients after the first evaluation to a more cost-effective strategy.
Teses / dissertações sobre o assunto "N6494"
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Durand, Corinne D. "The diffusion of Constructivist ideas in publications in Germany, 1918-1925". Thesis, University of St Andrews, 2001. http://hdl.handle.net/10023/14476.
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After a long period of disrupted communication, the years 1918-21 saw a rapid infiltration of Russian post-revolutionary culture into German progressive circles. In the thriving book market of Berlin, resourceful apologists like El Lissitzky and Il'ya Erenburg found conditions favourable to the diffusion of their ideas and played a critical role in encouraging pro-Soviet sentiment among the local vanguard. Their cosmopolitan enthusiasm, shared by a number of artists throughout Europe, bolstered hopes for co-operation between the modernist forces of all countries. For a brief while. Constructivism became a rallying point for those artists who had faith in their ability to foster cultural transformation and felt a common purpose in creating an environment conducive to social harmony. Various initiatives were taken to lay the foundation for a truly cohesive effort but yielded only temporary alliances. Serving as alternative platforms from which to gain influence and individual recognition, periodicals and slim book publications ultimately provided the main element of continuity in the attempt to found a Constructivist International. By 1925, those who had devoted most energy to this collective project had distanced themselves from a strong identification as Constructivists on the Berlin art scene and struck out in new directions.
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Marchevska, Elena. "The screen as a site of division and encounter". Thesis, University of Northampton, 2012. http://nectar.northampton.ac.uk/6130/.
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This study is a practice-based exploration of the screen as a border site, where the concepts of division and encounter are performatively examined. My research strategy is shaped by applying autoethnographic performance strategies to the mediated space of the screen. Media materials (photos, videos and blog entries) are created with mobile media devices used in performative situations, offering a theoretical framework originating in practice. The main argument is that the screen is an assemblage site, where the notions of division and encounter can be artistically explored. Furthermore, the screen is explored as an object, as a metaphor and as an idea. By linking the Latour notion of “assemblage” with Colley’s exploration of the personal use of mobile screens (“autobiometry”), and Ettinger’s notion of “borderspace” as site of artistic encounter, the practices presented in this thesis are located in a field that blurs the boundary between the personal and art; autobiography and autoethnography; technology and identity. In so doing, this thesis expands on previous explorations such as “boundary event” (Trinh T. Minh-ha 1999); “soft mastery” (Turkle 1995); and “screen-reliant art” (Moldoch 2010;). In the performative media materials created for this thesis, the screen is explored through a “processual approach” (Bacon, 2006). This enabled me to examine the nature of interaction with the screen through embodied reflexive practice. This approach firmly places the work in the experiential or performative realm. Key practices that are discussed in this thesis include among others, an earth body performative project by Ana Mendieta (Cuba/USA) entitled Silueta series (1973-1980), a live art work by Tanja Ostojic (Serbia/Germany) called Looking for a husband with EU passport (2000-2005) and my own performative media pieces, Valid until… (2010) and The place where we were last together (2011).
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Guth, Robert Ern-Yuan. "Engaging audiences to value and invest in participatory art practice through reciprocal and relational interactions". Phd thesis, 2012. http://hdl.handle.net/1885/151414.
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This research project examines certain forms of exchange and reciprocity in participatory art from a practitioner's perspective. It refers to aspects of Nicolas Bourriaud's Relational Aesthetics, touches on the food works of Rirkrit Tiravanija and uses practice-led research to examine audience interactions. In each research event the audience was given the opportunity to participate in some form of exchange, mostly involving food. Eight small research events and one larger work (staged in four editions) were produced. These works are examined as a means of gaining further knowledge of the stagecraft involved in my research practice and developing theoretical frameworks that can be used to better explain the inteactions occurring between people during these events. The outcomes from this investigation include a practical body of technical knowledge in making participatory art. The development o fthis expertise in practice-oedresearch can be seen in the increasing complexity of the research events, culminating in the final participatory event for examination. Tools were also developed, which focus on the indirect and direct reciprocal outcomes expected by participants ande artist, based on their engagement. These tools can equally be applied to the deconstruction of existing works to examine the mechanics of interaction or for the planning of future works.
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Shepherdson, Kerry Anne. "The nature of nature : an exploration of botanical themes, growth patterns and ornamental traditions, and the operation of metaphor and visual interpretations of life and growth as a means to abstraction in painting". Master's thesis, 2011. http://hdl.handle.net/1885/150189.
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The presentation of this Master of Philosophy thesis consists of studio practice-led research in the form of an exhibition of paintings at the School of Art Gallery from 16 March-1 April 2011, an exegesis giving a full account of the nature and development of the research undertaken during the course of the study, and two coursework components undertaken in the first year.
The work explores botanical themes, growth patterns and ornamental traditions, and the operation of metaphor and visual interpretations of life and growth as a means to abstraction in painting.
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Cheney, Jacqueline Patricia. "The mythology of the uncanny : as theory and practice in Australian contemporary art". Phd thesis, 2012. http://hdl.handle.net/1885/150841.
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A sensation raw and primal, unwelcome yet not wholly alien but peculiarly familiar, neither a penetrating roar nor shriek from the depths but a more eerily pervasive murmuring, without being discredited as irrational but instead being elevated within academia - the mythology of the uncanny persists.
This inquiry focusses on the phenomenon of the uncanny and its exemplification in the visual arts. Whilst extant literature relates uncanniness to the broader field of aesthetics, especially enlarged upon in literature, film-studies and architecture, it is a comparatively neglected topic in the context of visual arts. It is occasionally touched upon in texts concerning an artist's work, but usually very synoptically. Yet much art aligns to readings of uncanniness. For example, Sally Smart's evocatively uncanny work attracts descriptive smatterings about it without adequate enunciation against a critical theoretical framework.
Such a framework, newly developed here, takes into account Sigmund Freud's pivotal essay of 1919 whilst providing new interpretations of it and its subsequent plethoric discourse. Furthermore, this framework incorporates entirely different viewpoints, including Existentialist versions of uncanniness centred upon Martin Heidegger's and Jean-Paul Sartre's theories. Whilst being an evolution of the extensive discourse, my framework assimilates otherwise disparate notions of the uncanny effect and its sensations, then applies it contemporaneously.
In writing from the secularised worlds of Freudian psychoanalysis and Existentialism, religion, spirituality and mysticism are areas not intentionally ignored nor sidelined as unworthy of consideration. Nevertheless the scope of this dissertation required curtailing thereby making the exclusion of the non-secular a necessity. Psychophysical, neural and cognitive characteristics of viewers' sensory perception of artwork (in relation to evoking uncanniness) are other exclusions, and whilst I touch on various socio-political aspects of the uncanny, it likewise requires greater regard than what is allowed for herein.
This is essentially an interpretative analysis which applies a more broadly developed framework to six Australian artists whose work is persuasively uncanny: Ron Mueck, Patricia Piccinini, Sally Smart, Lawrence Daws, Pat Brassington and Bill Henson. These case-studies are structured into three chapters: the first concentrates on three-dimensional, figurative sculpture (Mueck and Piccinini); the next section looks at siting the uncanny in two-dimensional landscapes, specifically the locale of Australia, a land where the uncanny is said to loom large (Smart and Daws); whilst the final section focuses on uncanny 'filmic' surfaces or photo-based media (Brassington and Henson}. This form of analysis is founded on either the artist's self-identification with the topic and/or is based on consistent commentary about their artwork eliciting uncanniness, except Henson, who receives little discussion in relation to uncanniness, but, as demonstrated, epitomises it nonetheless.
Examining their art against a contemporary theoretical framework thus addresses a lacuna of critical, academic insight into the uncanniness of visual art, before drawing conclusions about some conceptual, technical and formal differences and similarities.
Livros sobre o assunto "N6494"
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M, Andrews, ed. Land art: A cultural ecology handbook. London: RSA, 2006.
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Museum of Contemporary Art (Los Angeles, Calif.), ed. Afterimage: Drawing through process. Los Angeles: Museum of Contemporary Art, 1999.
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van, Assche Christine, ed. Collection new media installations: La collection du Centre Pompidou, Musée national d'art moderne. [Paris: Editions du Centre Pompidou, 2006.
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Helmut, Friedel, e Städtische Galerie im Lenbachhaus München., eds. Geschichten des Augenblicks: Über Narration und Langsamkeit = Moments in time : on narration and slowness : James Coleman ... Ostfildern-Ruit: Hatje Cantz, 1999.
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Francis, Frascina, e Perry Gillian, eds. Primitivism, cubism, abstraction: The early twentieth century. New Haven: Yale University Press, in association with the Open University, 1993.
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Klaus, Honnef, Ruhrberg Karl, Fricke Christiane, Schneckenburger Manfred e Walther Ingo F, eds. Art of the 20th century. Köln: Taschen, 2000.
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Land Art: The Earth As Canvas (Taschen Basic Architecture Series). Taschen, 2007.
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Adventures of the Black Square: Abstract Art and Society 1915-2015. Prestel, 2015.
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Secret publicity: Essays on contemporary art. Rotterdam: NAi Publishers, 2005.
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Designs on Modernity: Exhibiting the City. Manchester University Press, 2004.
Encontre o texto completo da fonteTrabalhos de conferências sobre o assunto "N6494"
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Wilkowski, G., D. Rudland e H. Xu. "Examination of Service Cracks in CRDM Nozzles and Relevance to Flaw Evaluation Procedures". In ASME 2006 Pressure Vessels and Piping/ICPVT-11 Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/pvp2006-icpvt-11-93995.
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In Section XI of the ASME B&PV Code, a flaw evaluation procedure was recently developed for axial surface cracks in control-rod-drive mechanism (CRDM) nozzles in PWR reactor pressure vessel heads, i.e., Code Case N694-1 and IWB-3660. Some of the aspects of the analysis procedures are not rigorously defined due to numerous unknown aspects of this complicated problem. The U.S. operators of PWR plants were required by the NRC to make inspections of their CRDM nozzles and report the inspection results. The data was recently analyzed to assess how the flaw sizes develop and how that might provide guidance to the ASME flaw evaluation criterion. The results from numerous plants showed that the surface cracks tend to develop with a relatively constant aspect ratio for a certain plant, but that aspect ratio can significantly change from plant to plant. Using weld residual stresses and operating stresses with rigorous K-solutions for the depth and length of the surface cracks and the PWSCC crack growth rates, however, predicts surface flaws that would be much shorter in length than occur in service. It is suggested that rather than calculating the length of the surface flaws using the K-solutions, that the growth in the depth direction be calculated using the K-solutions (with some additional guidance) and the length be based on the aspect ratios found in the particular plants.