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Livros sobre o tema "Multicentric"

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Autor: Grafiati

Publicado: 7 de julho de 2024

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1

Dutta, Indranee. Abortion in Mizoram: A multicentric study. Guwahati: Omeo Kumar Das Institute of Social Change and Development, 2005.

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2

Salvatore, Sergio, Jaan Valsiner e Alessandro Gennaro. Multicentric identities in a globalizing world. Charlotte, NC: IAP, Information Age Publishing, Inc., 2014.

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3

Sharma, V. P. Seroepidemiology of human malaria: A multicentric study. Delhi: Malaria Research Centre, ICMR, 1989.

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4

Duggal, Ravi. Abortion services in India: Report of a multicentric enquiry. [Mumbai]: Centre for Enquiry into Health and Allied Themes, 2004.

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5

Helmut, Platz, Fries Rudolf, Hudec Marcus e German-Austrian-Swiss Association for Head and Neck Tumors., eds. Prognoses of oral cavity carcinomas: Results of a multicentric retrospective observational study. München: Hanser, 1986.

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6

S, Sriramachari, e Indian Council of Medical Research., eds. Indian childhood cirrhosis (ICC): A multicentric national collaborative study of ICMR (1983-1987). New Delhi: Indian Council of Medical Research, 2006.

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7

Gatti, Uberto. La delinquenza giovanile in Italia: I risultati di una ricerca multicentrica. Lecce: Pensa multimedia, 2010.

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8

Gatti, Uberto. La delinquenza giovanile in Italia: I risultati di una ricerca multicentrica. Lecce: Pensa multimedia, 2010.

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9

Armin, Schmidtke, ed. Suicidal behaviour in Europe: Results from the WHO/Euro multicentre study on suicidal behaviour. Cambridge, MA: Hogrefe & Huber, 2004.

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10

Tscherne, H. Beckenverletzungen: Ergebnisse einer prospektiven, multizentrischen Studie = Pelvic injuries : results of a prospective multicentre study. New York: Springer-Verlag, 1997.

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11

Heinrich, Spoendlin, ed. Multicentre evaluation of the temporal bones obtained from a patient with suspected Menière's disease. Stockholm: Scandinavian University Press, 1992.

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12

World Health Organization. Regional Office for South-East Asia., ed. Multicentre study on low birth weight and infant mortality in India, Nepal, and Sri Lanka. New Delhi: World Health Organization, Regional Office for South-East Asia, 1994.

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13

Knowelden, J. Post neonatal mortality: A multicentre study undertaken by the Medical Care Research Unit, University of Sheffield. London: H.M.S.O., 1985.

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14

Ad, Kerkhof, e Nederlands Instituut voor Voortgezet Wetenschappelijk Onderzoek op het Gebied van de Mens- en Maatschappijwetenschappen., eds. Attempted suicide in Europe: Findings from the multicentre study on parasuicide by the WHO Regional Office for Europe. Leiden: DSWO Press, Leiden University, 1994.

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15

World Health Organization. Division of Family Health. Maternal Health andSafe Motherhood Programme., ed. The Partograph: The application of the WHO partograph in themanagement of labour : report of a WHO multicentre study 1990-1991. Geneva: Division of Family Health, WHO, 1994.

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16

M, Kennedy A. D., e National Co-ordinating Centre for HTA (Great Britain), eds. A multicentre randomised controlled trial assessing the costs and benefits of using structured information and analysis of women's preferences in the management of menorrhagia. Alton: Core Research on behalf of the NCCHTA, 2003.

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17

H, Kinley, e National Co-ordinating Centre for HTA (Great Britain), eds. Extended scope of nursing practice: A multicentre randomised controlled trial of appropriately trained nurses and pre-registration house officers in pre-operative assessment in elective general surgery. Alton: Core research on behalf of NCCHTA, 2001.

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18

Sharma, Poonam. Seroepidemiology of Human Malaria ; A Multicentric Study. Malaria Research Centre, 1989.

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19

Cheng, Meiling. In Other Los Angeleses: Multicentric Performance Art. University of California Press, 2002.

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20

Seroepidemiology of human malaria: A multicentric study. Delhi: Malaria Research Centre, 1989.

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21

Fiorentini, Erna. On Visualization: A Multicentric Critique Beyond Infographics. Lit Verlag, 2021.

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22

Cheng, Meiling. In Other Los Angeleses: Multicentric Performance Art. University of California Press, 2002.

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23

Cheng, Meiling. In Other Los Angeleses: Multicentric Performance Art. University of California Press, 2002.

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24

Mosupyoe, Boatamo Yvonne. Women's Multicentric Ways of Knowing Being and Thinking. McGraw-Hill Primis Custom Publishing, 1998.

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25

Mosupyoe, Dr Boatamo. Women's Multicentric Ways of Knowing Being, and Thinking 2nd Edition. McGraw-Hill Primis Custom Publishing, 1999.

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26

Lim, Chin Ming Stephen. Contextual Biblical Hermeneutics As Multicentric Dialogue: Towards a Singaporean Reading of Daniel. BRILL, 2019.

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27

Jafri, Mariam, e Eamonn R. Maher. Genetics and molecular biology of renal cancer. Editado por James W. F. Catto. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0084.

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Renal cell carcinoma (RCC) is the exemplar of how the understanding of the molecular pathogenesis of rare inherited disorders can inform an understanding of the key pathways involved in the pathogenesis of sporadic cancer. In this chapter we describe the clinical and pathological features of the inherited kidney cancer syndromes: von Hippel Lindau disease (VHL); Birt-Hogg-Dube syndrome; hereditary leiomyomatosis and renal cancer syndrome; succinate dehydrogenase disorders; hereditary papillary renal cancer; and translocation-associated kidney cancer. Though individually rare, recognition of individuals with familial kidney cancer is important as they present specific clinical challenges to the urological surgeon because of their propensity to develop multicentric/bilateral tumours. Furthermore, different familial RCC predisposition syndromes are associated with different extra renal clinical features and have specific surveillance needs. Despite differences in clinical features, there is some overlap in the molecular pathophysiology between the disorders and these highlight the key signalling pathways for RCC oncogenesis.

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28

Multicentrism as an emerging paradigm in legal theory. Frankfurt am Main: Peter Lang, 2009.

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29

Jones, Byron. The Design and Analysis of Multicentre Clinical Trials. John Wiley and Sons Ltd, 2008.

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30

Little, Paul. Otitis media with effusion. Editado por John Phillips e Sally Erskine. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834281.003.0072.

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31

International Agency for Research on Cancer. European Multicentre Case-control Study of Lung Cancer in Non-smokers (IARC Technical Report). World Health Organization, 1998.

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32

EVALUATE hysterectomy trial: A multicentre randomised trial comparing abdominal, vaginal and laparoscopic methods of hysterectomy. Tunbridge Wells: Gray Publishing on behalf of NCCHTA, 2004.

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33

Diaz-Granados, Natalia. Predictors of low bone mineral density among Canadian men: Data from the Canadian multicentre osteoporosis study. 2003.

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34

Marcus, Eric, Francesco Pagano e Bassi. Suicide and Suicide attempts in Europe: Findings from the WHO/Euro Multicentre Study of Suicidal Behaviour (1st ed). Hogrefe & Huber Publishing, 2004.

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35

Kamerman, Peter. Recognizing the importance of HIV disease and pain. Editado por Paul Farquhar-Smith, Pierre Beaulieu e Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0056.

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The landmark paper discussed in this chapter is ‘Underestimation and undertreatment of pain in HIV disease: Multicentre study’, published by Larue in 1997. This study provided the first national assessment of pain intensity, prevalence, type, treatment, and risk factors influencing treatment in HIV-infected individuals across a wide range of disease stages. The authors showed that pain was common, was often of clinically significant intensity, got more common and severe with worsening disease stage, produced significant decreases in quality of life, and frequently was undertreated. Importantly, the study highlighted the underestimation of patient pain by doctors, which contributed to the undertreatment of pain.

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36

Pinto, Marsha M. The relationship of night sweats and bone change in perimenopausal and menopausal women in a population-based sample from the Canadian Multicentre Osteoporosis Study. 2006.

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37

A Multicentre randomised controlled trial assessing the costs and benefits of using structures information and analysis of women's preferences in the management of menorrhagia. Southampton: NCCHTA, 2003.

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38

Menezes, Natasja M. Tracking outcomes from first episode psychosis in Ontario: A descriptive multicentre study examining the outcomes and predictors of outcome in four first episode psychosis programs. 2006.

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39

Schwitter, Juerg. Coronary artery disease. Editado por Dudley Pennell. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0105.

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In the work-up of suspected or known coronary artery disease (CAD), cardiovascular magnetic resonance (CMR) is an established technique and it is recommended by most recent guidelines. Stress dobutamine and stress perfusion CMR yield sensitivities and specificities to detect anatomically defined CAD (>50% coronary stenoses) ranging from 83% to 91% and from 83% to 86%, respectively, with areas under the receiver operating characteristic curve (AUCs) of 0.80–0.93. Multicentre trials report AUCs of 0.75–0.91 to detect CAD and showed superiority over scintigraphic techniques. Increasing evidence in thousands of patients demonstrates the highly predictive value of CMR. Exclusion of ischaemia by CMR goes along with excellent event-free survival rates of 0.5–0.9%/year. Cost analyses in large data sets (e.g. in the European CMR registry), suggest considerable cost savings for CMR over first-line invasive strategies in suspected CAD. Tissue characterization by CMR to detect scar, necrosis, oedema, microvascular obstruction, or haemorrhage is of particular importance in the setting of acute coronary syndromes and this application is emerging as the number of centres offering CMR increases.

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40

Eleftheriou, Despina, e Paul A. Brogan. Paediatric vasculitis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0136.

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Systemic vasculitis is characterized by blood vessel inflammation which may lead to tissue injury from vascular stenosis, occlusion, aneurysm, and/or rupture. Apart from relatively common vasculitides such as Henoch-Schönlein purpura (HSP) and Kawasaki's disease (KD), most of the primary vasculitic syndromes are rare in childhood, but are associated with significant morbidity and mortality. New classification criteria for childhood vasculitis have recently been proposed and validated. The cause of most vasculitides is unknown, although it is likely that a complex interaction between environmental factors such as infections and inherited host responses trigger the disease and determine the vasculitis phenotype. Several genetic polymorphisms in vasculitis have now been described that may be relevant in terms of disease predisposition or development of disease complications. Treatment regimens continue to improve, with the use of different immunosuppressive medications and newer therapeutic approaches such as biologic agents. We provide an overview of paediatric vasculitides focusing on HSP, KD, and polyarteritis nodosa (PAN). Key differences (where relevant) between paediatric and adult vasculitis are highlighted. In addition we discuss new emerging challenges particularly in respect to the long-term cardiovascular morbidity for children with systemic vasculitis, and emphasize the importance of future international multicentre collaborative studies to further increase and standardize the scientific base of investigating and treating childhood vasculitis.

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41

Kuypers, Dirk R. J., e Maarten Naesens. Immunosuppression. Editado por Jeremy R. Chapman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0281_update_001.

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Combination immunosuppressive therapy produces excellent short-term results after kidney transplantation. Long-term graft survival has improved, but less dramatically. Death with a functioning graft remains the primary cause of graft loss. Dosing of current immunosuppressive therapy balances between careful clinical interpretation of time-driven immunological risk assessments and drug-related toxicity on the one hand, and the use of simple surrogate drug exposure indicators like blood/plasma concentrations on the other. The combined use of calcineurin-inhibitors (CNIs) with mycophenolic acids and corticosteroids has been fine-tuned over the last decade, based on empirically derived observations as well as on the results of large multicentre randomized clinical studies. Corticosteroid withdrawal and avoidance are feasible, at least in patients with a low immunological risk, but CNI-free protocols have had few long-term successes. Some minimization strategies have increased risk of developing acute rejection or (donor-specific) anti-HLA antibodies, with deleterious effects on the graft. Mammalian target of rapamycin inhibitors (mTORi) have shown limited benefit in early CNI replacement regimens and their long-term use as primary drug is hampered by intolerance. In the setting of particular malignant disease occurring after transplantation, such as squamous cell carcinoma of the skin and Kaposi’s sarcoma, mTORi seem promising. Induction agents (anti-interleukin 2 receptor monoclonal antibodies, antithymocyte globulins) effectively diminish the risk of early immunological graft loss in recipients with moderate to high immunological risk but at the price of more infectious or malignant complications. While personalized transplantation medicine is only in its early stages of development, attempts are made to quantitatively measure the clinical degree of immunosuppression, to tailor immunosuppressive therapy more specifically to the patient’s individual profile, and to monitor graft status by use of invasive (e.g. surveillance renal biopsies) and non-invasive biomarkers. These scientific endeavours are a necessity to further optimize the current immunosuppressive therapy which will remain for some time to come.

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