Literatura científica selecionada sobre o tema "Mouse Brain Organoids"
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Artigos de revistas sobre o assunto "Mouse Brain Organoids"
Roosen, Mieke, Chris Meulenbroeks, Phylicia Stathi, Joris Maas, Julie Morscio, Jens Bunt e Marcel Kool. "BIOL-11. PRECLINICAL MODELLING OF PEDIATRIC BRAIN TUMORS USING ORGANOID TECHNOLOGY". Neuro-Oncology 25, Supplement_1 (1 de junho de 2023): i8. http://dx.doi.org/10.1093/neuonc/noad073.030.
Texto completo da fonteSimsa, Robin, Theresa Rothenbücher, Hakan Gürbüz, Nidal Ghosheh, Jenny Emneus, Lachmi Jenndahl, David L. Kaplan, Niklas Bergh, Alberto Martinez Serrano e Per Fogelstrand. "Brain organoid formation on decellularized porcine brain ECM hydrogels". PLOS ONE 16, n.º 1 (28 de janeiro de 2021): e0245685. http://dx.doi.org/10.1371/journal.pone.0245685.
Texto completo da fonteSukhinich, K. K., K. M. Shakirova, E. B. Dashinimaev e M. A. Aleksandrova. "Development of 3D Cerebral Aggregates in the Brain Ventricles of Adult Mice". Russian Journal of Developmental Biology 52, n.º 3 (maio de 2021): 164–75. http://dx.doi.org/10.1134/s1062360421030061.
Texto completo da fonteBao, Zhongyuan, Kaiheng Fang, Zong Miao, Chong Li, Chaojuan Yang, Qiang Yu, Chen Zhang, Zengli Miao, Yan Liu e Jing Ji. "Human Cerebral Organoid Implantation Alleviated the Neurological Deficits of Traumatic Brain Injury in Mice". Oxidative Medicine and Cellular Longevity 2021 (22 de novembro de 2021): 1–16. http://dx.doi.org/10.1155/2021/6338722.
Texto completo da fonteFerdaos, Nurfarhana, Sally Lowell e John O. Mason. "Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains". PLOS ONE 17, n.º 11 (28 de novembro de 2022): e0278147. http://dx.doi.org/10.1371/journal.pone.0278147.
Texto completo da fonteGarcía-Delgado, Ana Belén, Rafael Campos-Cuerva, Cristina Rosell-Valle, María Martin-López, Carlos Casado, Daniela Ferrari, Javier Márquez-Rivas, Rosario Sánchez-Pernaute e Beatriz Fernández-Muñoz. "Brain Organoids to Evaluate Cellular Therapies". Animals 12, n.º 22 (15 de novembro de 2022): 3150. http://dx.doi.org/10.3390/ani12223150.
Texto completo da fonteYakoub, Abraam M., e Mark Sadek. "Analysis of Synapses in Cerebral Organoids". Cell Transplantation 28, n.º 9-10 (4 de junho de 2019): 1173–82. http://dx.doi.org/10.1177/0963689718822811.
Texto completo da fonteEstridge, R. Chris, Jennifer E. O’Neill e Albert J. Keung. "Matrigel Tunes H9 Stem Cell-Derived Human Cerebral Organoid Development". Organoids 2, n.º 4 (5 de outubro de 2023): 165–76. http://dx.doi.org/10.3390/organoids2040013.
Texto completo da fonteAntonica, Francesco, Lucia Santomaso, Davide Pernici, Linda Petrucci, Giuseppe Aiello, Alessandro Cutarelli, Luciano Conti et al. "MODL-22. Establishment of a novel system to specifically trace and ablate quiescent/slow cycling cells in high-grade glioma". Neuro-Oncology 24, Supplement_1 (1 de junho de 2022): i173. http://dx.doi.org/10.1093/neuonc/noac079.645.
Texto completo da fonteAntonica, F., L. Santomaso, G. Aiello, D. Pernici, E. Miele e L. Tiberi. "OS13.3.A Establishment of a novel system to specifically trace and ablate quiescent/slow cycling cells in high-grade glioma". Neuro-Oncology 23, Supplement_2 (1 de setembro de 2021): ii16. http://dx.doi.org/10.1093/neuonc/noab180.051.
Texto completo da fonteTeses / dissertações sobre o assunto "Mouse Brain Organoids"
Koshy, Aysis. "Characterization of Neural Development : Linking Retinoic Acid Receptors to Cell Fate and Modelling Tumorigenesis in Brain Organoids". Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASL119.
Texto completo da fonteThe development of the Central Nervous system in the embryo depends on timely and precise signaling of molecules. Retinoic acid is one such molecule well characterized for its impact in brain and eye development. In its metabolically active form, ATRA (All Trans Retinoic acid) binds Retinoic acid receptors (RAR), and controls downstream gene expression attributed to cell maturation and apoptosis. The RAR exists as three isotypes - RARα, RARβ, & RARγ. During embryological development, each isotype is present in spatially distinct locations influencing patterning and maturation. The current state of research is limited to the correlation of a specific RAR isotype to a particular cell fate. In this thesis, we discuss findings that point to the ability of RARβ & RARγ to synergistically restore cell specialization by hijacking RARα-controlled gene programs. In a single-cell RNAseq approach, we are able to visualize several clusters unique to RARβ + RARγ activation during mouse stem cell differentiation beyond neuronal precursor stages. In a similar vein, studying nervous tissue development in the context of diseases is relevant to understanding disease characteristics and identifying targeted therapy options. With this in mind, we wanted to develop a mouse brain organoid (BORG) model from H3.3K27M and H3.3G34R mutant mouse ES cells as an invitro research model that is cost effective and reproducible. Here, we show proof of a tumorigenic like mouse BORG that harbors a TP53 knockout signature