Literatura científica selecionada sobre o tema "Microtubule aster"
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Artigos de revistas sobre o assunto "Microtubule aster"
Bringmann, Henrik. "Mechanical and genetic separation of aster- and midzone-positioned cytokinesis". Biochemical Society Transactions 36, n.º 3 (21 de maio de 2008): 381–83. http://dx.doi.org/10.1042/bst0360381.
Texto completo da fonteTse, Yu Chung, Alisa Piekny e Michael Glotzer. "Anillin promotes astral microtubule-directed cortical myosin polarization". Molecular Biology of the Cell 22, n.º 17 (setembro de 2011): 3165–75. http://dx.doi.org/10.1091/mbc.e11-05-0399.
Texto completo da fonteSider, J. R., C. A. Mandato, K. L. Weber, A. J. Zandy, D. Beach, R. J. Finst, J. Skoble e W. M. Bement. "Direct observation of microtubule-f-actin interaction in cell free lysates". Journal of Cell Science 112, n.º 12 (15 de junho de 1999): 1947–56. http://dx.doi.org/10.1242/jcs.112.12.1947.
Texto completo da fonteNguyen, P. A., C. M. Field e T. J. Mitchison. "Prc1E and Kif4A control microtubule organization within and between large Xenopus egg asters". Molecular Biology of the Cell 29, n.º 3 (fevereiro de 2018): 304–16. http://dx.doi.org/10.1091/mbc.e17-09-0540.
Texto completo da fonteKotani, Tomoya, e Masakane Yamashita. "Overexpression of truncated γ-tubulins disrupts mitotic aster formation in Xenopus oocyte extracts". Biochemical Journal 389, n.º 3 (26 de julho de 2005): 611–17. http://dx.doi.org/10.1042/bj20050243.
Texto completo da fonteDogterom, M., M. A. Félix, C. C. Guet e S. Leibler. "Influence of M-phase chromatin on the anisotropy of microtubule asters." Journal of Cell Biology 133, n.º 1 (1 de abril de 1996): 125–40. http://dx.doi.org/10.1083/jcb.133.1.125.
Texto completo da fonteTanimoto, Hirokazu, Akatsuki Kimura e Nicolas Minc. "Shape–motion relationships of centering microtubule asters". Journal of Cell Biology 212, n.º 7 (28 de março de 2016): 777–87. http://dx.doi.org/10.1083/jcb.201510064.
Texto completo da fonteZhang, C., M. Hughes e P. R. Clarke. "Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts". Journal of Cell Science 112, n.º 14 (15 de julho de 1999): 2453–61. http://dx.doi.org/10.1242/jcs.112.14.2453.
Texto completo da fonteSchroeder, M. M., e D. L. Gard. "Organization and regulation of cortical microtubules during the first cell cycle of Xenopus eggs". Development 114, n.º 3 (1 de março de 1992): 699–709. http://dx.doi.org/10.1242/dev.114.3.699.
Texto completo da fonteSchroeder, T. E., e D. E. Battaglia. ""Spiral asters" and cytoplasmic rotation in sea urchin eggs: induction in Strongylocentrotus purpuratus eggs by elevated temperature." Journal of Cell Biology 100, n.º 4 (1 de abril de 1985): 1056–62. http://dx.doi.org/10.1083/jcb.100.4.1056.
Texto completo da fonteTeses / dissertações sobre o assunto "Microtubule aster"
Tramontozzi, Peter J. "Microtubule Dynamics During Sperm Aster Centration in Fertilized Sea Urchin Cells". Thesis, Boston College, 2018. http://hdl.handle.net/2345/bc-ir:108018.
Texto completo da fonteCentration of the nucleus after fertilization is an essential step for setting-up cell division and proper embryonic development in many proliferating cells such as the sea urchin. The sperm aster must capture the female pronucleus for fusion as well as the nucleus becoming positioned at the center of the cell. Microtubules (MTs) are known to play a role in this centration but the exact mechanism remains unknown. This begins to investigate current models of nuclear centration and the role of various interactions. Three phases of migration were observed as the male aster migrated with support in independent movements of the male and female pronuclei. Dimpling affects present that altered the morphology of the cell were observed when engagement occurred between the male and female pronuclei. It was discovered that this dimpling effect was a result of an interaction between MTs and the cortex, as confirmed by visualization of sheared cells in which only the cortex remained. Stemming from previous and current research in the lab, the role of post-translational modifications (PMTs) in nuclear centration was investigated for the different forces exerted due to various factors. Tyrosinated and detyrosinated populations were observed with and without the presence of parthenolide (PTL), an agent that inhibits detyrosination. PTL was observed to not only prevent the proper migration, but also that it expanded tyrosination of tubulin – which would further disrupt the force vectors created through the PMTs promotion of dyneins and kinesins. The results have lead to a new hypothesis to be furthered in order to gain an in-depth understanding in the mechanism(s) for pronuclear migration
Thesis (BS) — Boston College, 2018
Submitted to: Boston College. College of Arts and Sciences
Discipline: Departmental Honors
Discipline: Biology
Meaders, Johnathan Lee. "Growth, Morphology, and Positioning of Microtubule Asters in Large Zygotes:". Thesis, Boston College, 2020. http://hdl.handle.net/2345/bc-ir:109018.
Texto completo da fonteMicrotubule (MT) asters are radial arrays of MTs nucleated from a microtubule organizingcenter (MTOC) such as the centrosome. Within many cell types, which display highly diverse size and shape, MT asters orchestrate spatial positioning of organelles to ensure proper cellular function throughout the cell cycle and development. Therefore, asters have adopted a wide variety of sizes and morphologies, which are directly affects how they migrate and position within the cell. In large cells, for example during embryonic development, asters growth to sizes on the scales of hundreds of microns to millimeters. Due to this relatively enormous size scale, it is widely accepted that MT asters migrate primarily through pulling mechanisms driven by dynein located in the cytoplasm and/or the cell cortex. Moreover, prior to this dissertation, significant contributions from pushing forces as a result of aster growth and expansion against the cell cortex have not been detected in large cells. Here we have reinvestigated sperm aster growth, morphology, and positioning of MT asters using the large interphase sperm aster of the sea urchin zygote, which is historically a powerful system due to long range migration of the sperm aster to the geometric cell center following fertilization. First, through live-cell quantification of sperm aster growth and geometry, chemical manipulation of aster geometry, inhibition of dynein, and targeted chemical ablation, we show that the sperm aster migrates to the zygote center predominantly through a pushing-based mechanism that appears to largely independent of proposed pulling models. Second, we investigate the fundamental principles for how sperm aster size is determined during growth and centration. By physically manipulating egg size, we obtain samples of eggs displaying a wide range of diameters, all of which are at identical developmental stages. Using live-cell and fluorescence microscopy, we find strong preliminary evidence that aster diameter and migration rates show a direct, linear scaling to cell diameter. Finally, we hypothesize that a collective growth model for aster growth, or centrosome independent MT nucleation, may explain how the sperm aster of large sea urchin zygotes overcomes the proposed physical limitations of a pushing mechanism during large aster positioning. By applying two methods of super resolution microscopy, we find support for this collective growth model in the form of MT branching. Together, we present a model in which growth of astral MTs, potentially through a collective growth model, pushes the sperm aster to the zygote center
Thesis (PhD) — Boston College, 2020
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Biology
Ishihara, Keisuke. "On the growth of microtubule asters spanning millimeter-sized cells". Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:26718712.
Texto completo da fonteSystems Biology
Saffin, Jean-Michel. "Asap : Identification et caractérisation d'une nouvelle protéine associée aux microtubules". Montpellier 1, 2007. http://www.theses.fr/2007MON13508.
Texto completo da fonteGhasemalizadeh, Farid [Verfasser], Philippe [Akademischer Betreuer] Bastiaens e Leif [Gutachter] Dehmelt. "Recursive interaction between encapsulated dynamic microtubule asters and deformable membranes / Farid Ghasemalizadeh ; Gutachter: Leif Dehmelt ; Betreuer: Philippe Bastiaens". Dortmund : Universitätsbibliothek Dortmund, 2019. http://d-nb.info/1213975972/34.
Texto completo da fonteCapítulos de livros sobre o assunto "Microtubule aster"
Tanimoto, H., e N. Minc. "Quantitative approaches for the study of microtubule aster motion in large eggs". In Methods in Cell Biology, 69–80. Elsevier, 2017. http://dx.doi.org/10.1016/bs.mcb.2016.12.003.
Texto completo da fonte