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Bibliografias temáticas / Microbial modulation

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Literatura científica selecionada sobre o tema "Microbial modulation"

Autor: Grafiati

Publicado: 7 de dezembro de 2024

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Artigos de revistas sobre o assunto "Microbial modulation"

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Ash, Caroline. "Microbial modulation of diabetes". Science 359, n.º 6380 (8 de março de 2018): 1114.3–1114. http://dx.doi.org/10.1126/science.359.6380.1114-c.

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Brown, J. Mark, e Stanley L. Hazen. "Microbial modulation of cardiovascular disease". Nature Reviews Microbiology 16, n.º 3 (8 de janeiro de 2018): 171–81. http://dx.doi.org/10.1038/nrmicro.2017.149.

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Khan, Muhammad Tanweer, Max Nieuwdorp e Fredrik Bäckhed. "Microbial Modulation of Insulin Sensitivity". Cell Metabolism 20, n.º 5 (novembro de 2014): 753–60. http://dx.doi.org/10.1016/j.cmet.2014.07.006.

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Goel, Ajay Kumar, N. Dilbaghi, Dev Vrat Kamboj e Lokendra Singh. "Probiotics: Microbial Therapy for Health Modulation". Defence Science Journal 56, n.º 4 (1 de julho de 2006): 513–29. http://dx.doi.org/10.14429/dsj.56.1917.

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Sparvoli, Luiz G., Ramon V. Cortez, Silvia Daher, Marina Padilha, Sue Y. Sun, Mary U. Nakamura e Carla R. Taddei. "Women's multisite microbial modulation during pregnancy". Microbial Pathogenesis 147 (outubro de 2020): 104230. http://dx.doi.org/10.1016/j.micpath.2020.104230.

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Skye, Sarah M., e Stanley L. Hazen. "Microbial Modulation of a Uremic Toxin". Cell Host & Microbe 20, n.º 6 (dezembro de 2016): 691–92. http://dx.doi.org/10.1016/j.chom.2016.11.005.

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Chilimoniuk, Zuzanna, Dominik Dudziński, Aleksandra Borkowska, Aleksandra Chałupnik, Piotr Więsyk, Beata Chilimoniuk, Łukasz Gawłowicz, Filip Grzegorzak e Katarzyna Stasiak. "Correlation between gut microbiota dysbiosis and colorectal cancer: review". Quality in Sport 22 (18 de setembro de 2024): 54326. http://dx.doi.org/10.12775/qs.2024.22.54326.

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Introduction and Purpose: The human gut microbiota, comprising a diverse consortium of approximately 100 trillion microorganisms, is integral to maintaining health and modulating disease processes. Its development begins at birth, influenced by maternal microbiota and environmental factors. Dysbiosis, defined as an imbalance in the gut microbial composition, has been implicated in a range of gastrointestinal pathologies, including colorectal cancer (CRC). This review endeavors to elucidate the relationship between gut microbiota and CRC, examining the impact of specific bacterial taxa on the pathogenesis CRC. Description of the State of Knowledge: Gut microbiota encompasses a multitude of microbial species, with their composition differing along the gastrointestinal tract. Healthy gut microbiota perform essential functions such as pathogen protection, metabolic processes, and immune system modulation. Factors like diet and genetics significantly influence microbial composition. Dysbiosis contributes to CRC through inflammation, genotoxin production, and immune modulation. Specific bacteria, such as Fusobacterium nucleatum and Bacteroides fragilis, are associated with CRC. Mechanisms of carcinogenesis include bacterial adherence, invasion of epithelial cells, and activation of pro-inflammatory pathways. Summary:Understanding the gut microbiota's role in CRC highlights the importance of maintaining a balanced microbiome for cancer prevention. Dietary interventions promoting beneficial bacteria and reducing harmful species could mitigate CRC risk. Further research should prioritize the identification of microbial biomarkers for early CRC detection and the development of therapeutic strategies aimed at modulating the gut microbiota. These efforts will enhance CRC prevention and treatment modalities.

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Vamanu, Emanuel. "Complementary Functional Strategy for Modulation of Human Gut Microbiota". Current Pharmaceutical Design 24, n.º 35 (24 de janeiro de 2019): 4144–49. http://dx.doi.org/10.2174/1381612824666181001154242.

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Two pathologies commonly associated with gut microbiota dysbiosis are type 2 diabetes and cardiovascular diseases. Since diet and medication are two important causes of microbiome fingerprint modifications, new complementary and alternative methods can include wild edible mushrooms, which serve as functional products, given their properties in modulating the microbial pattern at the colon level. A disturbance in microbial balance translates into the occurrence of degenerative dysfunctions that are also associated with other pathologies, such as obesity, colon cancer. The metagenomic study has enabled the identification of some competitive microbiological and biochemical biomarkers which allow the development of innovative strategies in controling microbial disbalance from human gut. Thus, the aim of this review was to present the significant findings related to human microbiome modulation via the prebiotic effects of wild edible mushrooms as a complementary strategy to modern treatment. Certain mushroom species have been approached and their effects on the microbiota fingerprint of two major target groups are highlighted.

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Cayuela, Miguel Freitas, Chantal. "Microbial Modulation of Host Intestinal Glycosylation Patterns". Microbial Ecology in Health and Disease 12, n.º 2 (janeiro de 2000): 165–78. http://dx.doi.org/10.1080/089106000750060422.

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Spisni, Enzo, Giovannamaria Petrocelli, Veronica Imbesi, Renato Spigarelli, Demetrio Azzinnari, Marco Donati Sarti, Massimo Campieri e Maria Chiara Valerii. "Antioxidant, Anti-Inflammatory, and Microbial-Modulating Activities of Essential Oils: Implications in Colonic Pathophysiology". International Journal of Molecular Sciences 21, n.º 11 (10 de junho de 2020): 4152. http://dx.doi.org/10.3390/ijms21114152.

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Essential oils (EOs) are a complex mixture of hydrophobic and volatile compounds synthesized from aromatic plants, most of them commonly used in the human diet. In recent years, many studies have analyzed their antimicrobial, antioxidant, anti-inflammatory, immunomodulatory and anticancer properties in vitro and on experimentally induced animal models of colitis and colorectal cancer. However, there are still few clinical studies aimed to understand their role in the modulation of the intestinal pathophysiology. Many EOs and some of their molecules have demonstrated their efficacy in inhibiting bacterial, fungi and virus replication and in modulating the inflammatory and oxidative processes that take place in experimental colitis. In addition to this, their antitumor activity against colorectal cancer models makes them extremely interesting compounds for the modulation of the pathophysiology of the large bowel. The characterization of these EOs is made difficult by their complexity and by the different compositions present in the same oil having different geographical origins. This review tries to shift the focus from the EOs to their individual compounds, to expand their possible applications in modulating colon pathophysiology.

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Mais fontes

Teses / dissertações sobre o assunto "Microbial modulation"

1

Johansson, Ulrika. "Modulation of human dendritic cell function by microbial or autologous stimuli". Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270951.

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Sasaki, Yusuke. "Synthetic Constitution and Modulation of Microbial Metabolic Systems for Advanced BioChemical Generation". Kyoto University, 2020. http://hdl.handle.net/2433/253449.

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付記する学位プログラム名: 京都大学大学院思修館
Kyoto University (京都大学)
0048
新制・課程博士
博士(総合学術)
甲第22613号
総総博第13号
新制||総総||2(附属図書館)
京都大学大学院総合生存学館総合生存学専攻
(主査)教授山口栄一, 教授山敷庸亮, 教授植田充美, 大嶌幸一郎
学位規則第4条第1項該当

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Smit, Flora [Verfasser]. "Cutaneous defense against Candida albicans: modulation of chemokine-driven anti-microbial immune responses / Flora Smit". Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2018. http://d-nb.info/1172500274/34.

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4

Tran, Thi Thu Hong. "Dietary modulation to improve pig health and performance /". Uppsala : Department of Animal Nutrition and Management, Swedish University of Agricultural Sciences, 2008. http://epsilon.slu.se/200891.pdf.

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Ganesan, Asha Purnima Veerappan. "A study of regulatory T cells and modulation of allergic immune responses by microbial agents in human asthma". Thesis, University of Southampton, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538955.

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6

Maître, Apolline. "Modulating the vector microbiota for the control of vector-borne pathogens". Electronic Thesis or Diss., Maisons-Alfort, École nationale vétérinaire d'Alfort, 2024. http://www.theses.fr/2024ENVA0005.

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Le cheptel corse, composé d'ovins, de caprins, de porcins et de bovins, est principalement élevé dans des systèmes d'élevage extensifs. Les interactions fréquentes entre le bétail, la faune sauvage et les populations humaines favorisent donc la circulation des tiques et des micro-organismes transmis par les tiques. Une forte prévalence de bactéries transmises par les tiques des familles Rickettsiaceae et Anaplasmataceae a été signalée chez les chèvres (Anaplasma ovis), les moutons (A. ovis), les bovins (Anaplasma marginale, Anaplasma phagocytophilum et Ehrlichia minasensis) et les tiques (Rickettsia spp.) en Corse. Certaines de ces bactéries (par exemple, A. phagocytophilum et Rickettsia sp.) sont zoonotiques et pathogènes pour l'homme. Actuellement, il n'existe pas de mesures préventives pour le contrôle des tiques et des maladies transmises par les tiques. Le microbiome des tiques est un ensemble très complexe de micro-organismes en interaction qui ont un impact sur la physiologie des tiques et leur compétence vectorielle. Récemment, nous avons montré que les vaccins anti-microbiote des tiques peuvent produire une mortalité élevée chez celles-ci pendant leur alimentation. Les vaccins anti-microbiotiques peuvent également moduler le microbiome des tiques et peuvent donc être utilisés comme outil de contrôle de la transmission des pathogènes transmis par les tiques. Dans ce projet, nous utiliserons le séquençage de nouvelle génération des amplicons 16S pour étudier la diversité taxonomique et fonctionnelle du microbiome de Rhipicephalus bursa et Hyalomma marginatum, les principales tiques vectrices de pathogènes chez le bétail en Corse. En utilisant les réseaux de co-occurrence et la détection à haut débit des pathogènes, nous identifierons ensuite les bactéries clés interagissant avec les pathogènes détectés transmis par les tiques. Les bactéries clés de voûte seront utilisées pour formuler des vaccins anti-microbiotiques afin de bloquer l'acquisition et/ou la transmission des pathogènes
The Corsican livestock population, composed of sheep, goats, pigs and cattle, is mainly raised in extensive farming systems. Frequent interactions between livestock, wildlife and human populations can favor the circulation of ticks and tick-borne microorganisms. A high prevalence of tick-borne bacteria of the families Rickettsiaceae and Anaplasmataceae has been reported in goats (Anaplasma ovis), sheep (A. ovis), cattle (Anaplasma marginale, Anaplasma phagocytophilum, and Ehrlichia minasensis) and ticks (Rickettsia spp.) in Corsica. Some of these bacteria (e.g., A. phagocytophilum and Rickettsia sp.) are zoonotic and pathogenic to humans. Currently, there are no preventive measures for the control of ticks and tick-borne diseases. The tick microbiome is a very complex set of interacting microorganisms that impact tick physiology and vector competence. Recently, we have shown that tick microbiota vaccines can produce high mortality in ticks during feeding. Anti-microbiota vaccines can also modulate the tick microbiome and thus can be used as a tool to control the transmission of tick-borne pathogens. In this project, we will use next-generation sequencing of 16S amplicons to study the taxonomic and functional diversity of the microbiome of Rhipicephalus bursa and Hyalomma marginatum, the main pathogen-vector ticks in cattle in Corsica. Using co-occurrence networks and high-throughput pathogen detection, we will then identify keystone bacteria interacting with the detected tick-borne pathogens. The keystone bacteria will be used to formulate antimicrobial vaccines to block pathogen acquisition and/or transmission

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7

Smida, Hassiba. "Modulation de l'interface entre biofilms microbiens électroactifs et surface d'électrode : modifications de surface et effets de milieux". Thesis, Rennes 1, 2017. http://www.theses.fr/2017REN1S135/document.

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Les piles à combustible microbiennes (PCMs) sont des dispositifs bio-électrochimiques qui utilisent des biofilms bactériens électroactifs afin de catalyser des réactions d'oxydoréduction anodique et/ou cathodique pour générer de l'énergie électrique. Afin de promouvoir le développement et la connexion des biofilms, points clé dans les performances des PCM, la surface de l'anode de graphite est fonctionnalisée par des unités pyridine. Celles-ci sont greffées de façon covalente via la réduction électrochimique de cations diazopyridinium, formés in situ à partir de précurseurs amine, en s'inspirant de la méthode d'électrogreffage des sels d'aryle diazonium. Cela permet d'obtenir une interface très robuste. En comparant la réactivité de différents dérivés aminopyridine et les propriétés des couches greffées résultantes, la réduction des cations para-diazopyridinium conduit à des films fins et compacts, bien adaptés pour favoriser l'adhésion bactérienne et le transfert d'électrons entre la surface de l'anode et les bactéries électroactives. La présence d'unités pyridine immobilisées en surface de l'anode permet un développement plus rapide du biofilm et des performances accrues de la PCM pour des biofilms jeunes. Par comparaison, une anode modifiée par des multicouches de polyphénylène puis colonisée par un biofilm bactérien se révèle moins efficace pour la catalyse de l'oxydation de l'acétate. La nature et les propriétés physicochimiques de l'électrolyte sont également un paramètre important dans le développement du biofilm bactérien. Les liquides ioniques à température ambiante présentent des propriétés uniques, notamment en termes de solvatation, et leur utilisation dans des applications biotechnologiques a récemment émergé. Toutefois, leurs effets sur les biofilms bactériens restent encore peu connus. L'ajout d'une sélection de liquides ioniques hydrophiles et hydrophobes à base de cations imidazolium ou pyridinium dans l'anolyte, même en très faible quantité, ou immobilisés à la surface de l'anode inhibe le développement du biofilm
Microbial Fuel Cells (MFCs) are bio-electrochemical devices based on electroactive bacterial biofilms which catalyze the electron transfer both at the anode and cathode to generate electrical power. To enhance the biofilms development and to improve the biofilm-electrode connection, being both key features in the performance of the MFC, the graphite anode was functionalized by pyridine units. In order to ensure a robust interface, pyridine units are grafted covalently through the electrochemical reduction of diazopyridinium cations in situ formed from aminopyridine precursors, following the well-known electrografting method for aryl diazonium salts. By comparing the reactivity of various aminopyridine derivatives and the resulting grafted layers properties, the para-diazopyridinium cations reduction results in a thin and compact layer, which is the best suited for promoting bacterial adhesion and favorable electron transfer between the anode surface and electroactive bacteria. The presence of pyridine units immobilized on the anode surface leads to a faster biofilm development together with increased MFC performances for young biofilms. In contrast, anode modified with polyphenylene multilayers and then colonized by a bacterial biofilm has been proved to be less effective for the catalysis of acetate oxidation. On the other hand, the nature of the electrolyte and the physicochemical properties are also important parameters for the bacterial biofilm development. Room temperature ionic liquids have unique properties, particularly in terms of solvation, and their use in biotechnological applications has recently emerged. However, their effects on bacterial biofilms remain little known. The addition of a selection of hydrophilic and hydrophobic ionic liquids based on imidazolium or pyridinium cations in the anolyte, even in very small quantities, or immobilized at the anode surface inhibited the biofilm development

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Banasaz, Mahnaz. "Intestinal cell kinetics : modulation caused by age, gender and microbial status in rats and mice : an experimental study in germfree, conventional and Lactobacillus rhamnosus GG or Clostridium difficile, mono-associated animals /". Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-241-8.

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9

Pham, Hoang-Nam. "Impact des métabolites secondaires de plantes sur des bactéries pathogènes de la rhizosphère : existe-t-il un lien entre la résistance sur métaux et la modulation de résistance aux antibiotiques ?" Thesis, Toulouse 3, 2017. http://www.theses.fr/2017TOU30153/document.

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L'objectif de cette thèse est d'évaluer les modifications du métabolisme secondaire des plantes contaminées aux éléments trace métalliques (ETM) et leurs conséquences sur les communautés bactériennes rhizosphériques associées incluant des bactéries présentant des phénotypes de MultiDrug Résistance (MDR). Nous nous sommes focalisés sur deux contextes de sols exposés aux métaux : la phytoremédiation de sites miniers au Vietnam et la reconversion de sols agricoles contaminés par la re-déposition atmosphérique d'activités métallurgiques en France. Nos résultats ont mis en évidence que la contamination par différents types de métaux (dont Cu et Pb principalement) a conduit à une altération de la production des métabolites secondaires des racines, tiges et feuilles de la plante hyperaccumulatrice Pteris vittata et que concernant les racines des tendances similaires dans les changements métaboliques ont pu être observés dans un autre type de contexte de pollution (Zn et Pb plus particulièrement). De même, les profils métaboliques des parties souterraines (racines et rhizomes) de Miscanthus x giganteus ont été modifiés par les concentrations en Pb, Cd et Zn des sols agricoles. Pour les deux plantes examinées des dérivés de l'acide chlorogénique ont été retrouvés en proportions augmentées dans les racines malgré des contextes de nature des sols et de pollutions métalliques très contrastés. Cependant, les dérivés de tanin catéchiques sont spécifiquement trouvés en proportions plus élevées dans les racines de P. vittata sous pression métallique. Ces polyphénols sont connus pour leur capacité à piéger les radicaux libres et leur pouvoir antioxydant et pourraient donc être impliqués dans l'adaptation de ces plantes au stress métallique en contribuant à limiter le stress oxydatif généré par les ETM. Au niveau des parties aériennes, nous n'avons étudié que le changement pour P. vittata et avons mis en évidence une proportion plus élevée de dérivés flavonoïdiques pour les plantes contaminées. Nos résultats de métagénomique nous permettent de conclure également sur un effet des ETM sur la diversité et la richesse spécifique des communautés bactériennes des sols étudiés : une forte contamination en Cu (10 fois la limite autorisée) a diminué la diversité et la richesse bactérienne, alors que pour des niveaux en ETM plus modérés incluant Cu, Pb et Zn, la diversité des communautés bactériennes rhizosphériques semble plus influencée par la plante ou la saison plutôt que par l'effet des ETM. Cet effet sur la composition bactérienne de la rhizosphère de P. vittata se traduit par un enrichissement de certains genres connus comme pathogènes opportunistes de l'homme, notamment Ralstonia, Acinetobacter, Burkholderia et Mycobacterium. En outre, le genre Cupriavidus, connu comme très résistant aux ETM est le seul genre spécifiquement associé à P. vittata qui ait été augmenté au sein de la communauté rhizosphérique pour les deux sites miniers étudiés par rapport aux sols rhizosphériques non pollués. Ce genre pourrait donc être impliqué dans le processus d'adaptation de cette plante au stress métallique. Quant aux communautés rhizosphériques de Miscanthus x giganteus, la sélection de Stenotrophomonas et Pseudomonas dans les sols agricoles contaminés a été observée. Dans le cadre de cette thèse nous avons également mis au point une méthode rapide pour tester l'impact de métabolites végétaux sur des souches pathogènes d'origine clinique et environnementale et également évaluer leur activité inhibitrice de pompes à efflux (IPE) de la famille des RND. Nos données ont ainsi permis de mettre en évidence des activités intéressantes et comparables à celle de l'inhibiteur de pompe à efflux PAßN pour des composés testés qui étaient extraits des racines de Fallopia x bohemica ou des dérivés de ces derniers
The objective of this thesis is to evaluate the modification of plant secondary metabolism production contaminated with metallic trace elements (MTE) and its consequences on the associated rhizospheric bacterial communities including bacteria presenting MultiDrug Resistant (MDR) phenotypes. We have focused on two contexts of metals exposure: the phytoremediation of mining sites in Vietnam and the reconversion of agricultural soils contaminated by the atmospheric re-deposition of metallurgical activities in France. Our results highlighted that contamination by different types of metals (mainly Cu and Pb) has led to an alteration in the production of secondary metabolites in the roots, stems and leaves of the hyper-accumulating Pteris vittata and for roots, a similar trend in the metabolic changes could be observed in another type of pollution context (Zn and Pb more particularly). Similarly, the metabolic profiles of the underground parts (roots and rhizomes) of Miscanthus x giganteus were modified by the concentrations of Pb, Cd and Zn in agricultural soils. For the two plants examined chlorogenic acid derivatives have been found in increased proportions in the roots despite soil type and pollution context were highly contrasted. However, catechic tannin derivatives are specifically found in higher proportions in the roots of P. vittata under metal pressure. These polyphenols are known for their ability to scavenge free radicals and their antioxidant properties and thus could be involved in the adaptation of these plants to metallic stress by helping to limit the oxidative stress generated by MTE. At the level of the aerial parts, we studied only the change for P. vittata and evidenced higher proportions of flavonoid derivatives for contaminated plants. Our metagenomic results allow us to conclude also on the effect of MTE on the diversity and the specific richness of the bacterial communities of the studied soils: a high contamination of Cu (10 times the allowed limit) decreased dramatically bacterial richness and diversity, while for more moderate MTE levels including Cu Pb and Zn, the diversity of rhizosphere bacterial communities was more explained by plant or season effect rather than an effect of MTE. This effect on P.vittata rhizosphere bacterial composition is reflected by an enrichment in genera known as opportunistic human pathogens, including Ralstonia, Acinetobacter, Burkholderia and Mycobacterium. In addition, Cupriavidus, known as a highly resistant genus, is the only P. vittata specifically associated genus found in increased proportions at both mining sites compared to non-contaminated rhizosphere soils. This genus could then be involved in the adaptation process of this plant with metal stress. As for the rhizospheric communities of Miscanthus x giganteus, the selection of Stenotrophomonas and Pseudomonas in agricultural soils contaminated with MTE was observed. As a part of this thesis, we have also developed a rapid method for testing the impact of plant metabolites on pathogenic strains of clinical and environmental origin and their efflux pump inhibition (EPI) activity of RND family. Our data thus showed interesting and notable EPI activities comparable to that of the efflux pump inhibitor PAßN for tested compounds issued from Fallopia x bohemica roots or for their derivatives

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Roussel, Perrine. "Entre glande mammaire et Escherichia coli : étude des intéractions qui conditionnent le déclenchement et l'issue des mammites : rôles des cellules épithéliales et modulation par l'IL-17A". Thesis, Tours, 2013. http://www.theses.fr/2013TOUR4046.

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L’intensification des pratiques d’élevage s’est accompagnée de l’émergence de pathologies de production, notamment des mammites. Il s’agit d’une inflammation de la glande mammaire, d’origine bactérienne dans la majeure partie des cas. Les mammites constituent à elles seules la première source de pertes financières des cheptels bovins laitiers en France et dans le monde. Néanmoins aucun traitement prophylactique ne permet à ce jour une action préventive à long terme. Parmi les agents étiologiques majeurs des mammites, Escherichia coli (E. coli) tient son importance du fait de sa prévalence et de son impact sur les rendements et la qualité du lait. La part des facteurs de l’hôte dans la capacité à éliminer le pathogène causal est relativement avérée, tandis que le lien entre caractéristiques bactériennes et sévérité de l’infection est plus délicat à établir. Cette étude s’attache donc à déterminer si les interactions entre E. coli et la glande mammaire, en particulier les cellules épithéliales mammaires (CEM) et les neutrophiles, peuvent expliquer des degrés de sévérité variables. L’influence du lait sur ces interactions a également été investiguée
Along with agricultural intensification of animal production, some pathologies have emerge, especially mastitis. This disease corresponds to an inflammation of the udder, and is generally provoked by bacterial infection. Mastitis on their own constitute the main source of financial impairments within dairy herds in France and worldwide. So far, there is no treatment able to prevent mastitis over time. Among major mastitis pathogens Escherichia coli (E. coli) is of great importance, because of its prevalence and its impacts on milk yield and quality. The mastitis severity has proven to be linked to host factors, but the implication of bacterial characteristics remains unknown. Thus, this study aimed at deciphering whether interactions between E. coli and the mammary gland, especially the mammary epithelial cells (MECs) and neutrophils, may explain a variability in mastitis severity. Influence of milk on these interactions was also investigated

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Mais fontes

Livros sobre o assunto "Microbial modulation"

1

L, Alberghina, Frontali Laura, Hamer G e European Federation of Biotechnology. Working Party on Microbial Physiology., eds. Physiological and genetic modulation of product formation: Microbial physiology for biotechnological innovation : proceedings of an international symposium, Como/I, 8-10 May 1986. Weinheim (Federal Republic of Germany): VCH, 1987.

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2

He, Yongqun, e Amal O. Amer, eds. Microbial Modulation of Host Apoptosis and Pyroptosis. Frontiers Media SA, 2014. http://dx.doi.org/10.3389/978-2-88919-280-9.

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3

Rahal, Elias Adel, Margret Shirinian e Daniele Dessì, eds. The Microbial Modulation of Autoimmune Processes and Proinflammatory Pathways. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-932-2.

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4

Alberghina, L. Physiological and Genetic Modulation of Product Formation (Dechema Monographs,). Wiley-VCH Verlag GmbH, 1998.

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Capítulos de livros sobre o assunto "Microbial modulation"

1

Bearson, Bradley L., e Scot E. Dowd. "Molecular Profiling: Catecholamine Modulation of Gene Expression in Enteropathogenic Bacteria". In Microbial Endocrinology, 229–41. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-5576-0_13.

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Stover, Cordula M. "Mechanisms of Stress-Mediated Modulation of Upper and Lower Respiratory Tract Infections". In Microbial Endocrinology, 181–89. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-5576-0_10.

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Huges, R., e I. Rowland. "Nutritional and Microbial Modulation of Carcinogenesis". In Gut Flora, Nutrition, Immunity and Health, 208–36. Oxford, UK: Blackwell Publishing Ltd, 2008. http://dx.doi.org/10.1002/9780470774595.ch10.

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Stevens, Mark P. "Modulation of the Interaction of Enteric Bacteria with Intestinal Mucosa by Stress-Related Catecholamines". In Microbial Endocrinology, 111–34. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-5576-0_6.

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Ali, Saira, e Asma Imran. "Plant Disease Management Through Microbiome Modulation". In Microbial Biocontrol: Sustainable Agriculture and Phytopathogen Management, 113–50. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-87512-1_5.

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Weisskopf, L., e A. Bailly. "Plant Growth Modulation by Bacterial Volatiles-A Focus onBurkholderiaSpecies". In Molecular Microbial Ecology of the Rhizosphere, 665–75. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118297674.ch63.

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Turrini, Federica, Raffaella Boggia, Paola Zunin e Francesco Michelangelo Turrini. "Modulation of the Host-Parasite Redox Metabolism to Potentiate Antimalarial Drug Efficiency". In Oxidative Stress in Microbial Diseases, 511–29. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-8763-0_27.

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Tashiro, Fumio, Shigeru Morimura, Nobuo Horikoshi, Kazuko Kato e Yoshio Ueno. "Deregulation of c-myc Gene and Modulation of Glucocorticoid Receptor by Aflatoxin B1". In Microbial Toxins in Foods and Feeds, 483–88. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-0663-4_44.

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Mitra, Aditee, e Kevin J. Flynn. "Exploring the Implications of the Stoichiometric Modulation of Planktonic Predation". In Aquatic Microbial Ecology and Biogeochemistry: A Dual Perspective, 77–89. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30259-1_7.

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Ansari, Waquar Akhter, Ram Krishna, Mohammad Tarique Zeyad, Shailendra Singh e Akhilesh Yadav. "Endophytic Actinomycetes-Mediated Modulation of Defense and Systemic Resistance Confers Host Plant Fitness Under Biotic Stress Conditions". In Microbial Versatility in Varied Environments, 167–80. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3028-9_10.

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Trabalhos de conferências sobre o assunto "Microbial modulation"

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Lee, Se Hee, Yoon Ok Jang, Jong Jin Choi, Yeon-Mok Oh e Sei Won Lee. "Gut microbial modulation attenuates emphysema development by suppressing inflammation and apoptosis". In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.312.

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McPherson, Alex C., Catherine Phelps, Mackenzie Bender, Colin Laughlin e Marlies Meisel. "1326 Modulation of the gut microbiota drives microbial translocation to the tumor microenvironment in melanoma". In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.1326.

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S, Zarin A., Arup Lal Chakraborty e Saumyakanti Khatua. "Correlating microbial bioluminescence to the different phases of growth using a 2004 nm VCSEL-based 2f wavelength modulation spectroscopy". In 2021 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC). IEEE, 2021. http://dx.doi.org/10.1109/cleo/europe-eqec52157.2021.9542159.

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Radu, Elena, F. Marinescu, I. Savin, M. Popa, G. Pircalabioru, Mihai Badic e C. Chifiriuc. "MODULATION OF THE ANTIBIOTIC SUSCEPTIBILITY PROFILES OF SOME MICROBIAL STRAINS ISOLATED FROM WASTEWATER UNDER THE INFLUENCE OF THE ELECTROMAGNETIC FIELD". In International Symposium "The Environment and the Industry". National Research and Development Institute for Industrial Ecology, 2016. http://dx.doi.org/10.21698/simi.2016.0043.

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Kumrungsee, Thanutchaporn, Norihisa Kato, Toshiro Matsui e Yongshou Yang. "Plant and gut microbiota-derived protein metabolites and potential health functions". In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/envt3719.

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Bioactive peptides can be obtained from protein hydrolysates through in vitro enzymatic hydrolysis, gastrointestinal digestion, and microbial fermentation. Recent emerging research suggests that prebiotic-stimulated gut microbiota also plays a role in generating bioactive peptides and amino acids in gut. In this study, we examined if enzymatic hydrolysis of soybean and wheat germ, plant materials often used in oil industry, can generate antihypertensive peptides and determined if prebiotic digestive enzymes can induce the production of gut microbiota-derived amino acids. In the first experiment, soybean and wheat germ were hydrolyzed by protease enzymes. Then, their hydrolysates were subjected to peptide isolation and identification. Identified peptides were subjected to test for their potential antihypertensive activities. For the second experiment, rodents were fed an Aspergillus-derived protease- or lipase-mixed diet for 2 weeks. Then, cecum contents were collected for bacteria and metabolite analyses. As a result, we found that His-Gly-Lys from soybean hydrolysate strongly inhibited angiotensin II-induced elevated intracellular Ca2+ concentration in vascular smooth muscle cells (VSMCs). Trp-Val and Trp-Ile from wheat germ hydrolysate were found to inhibit Ca2+-calmodulin (CaM)-dependent protein kinase II (CaMK II), a protein kinase promoting hypertension by inducing Ca2+ influx into VSMCs, in rat thoracic aorta rings. These findings suggest the potential of the plant-derived peptides in preventing hypertension and vascular-related diseases. In the second experiment, we found that the dietary protease and lipase increased Bifidobacterium and Lactobacillus probiotics and induced the production of probiotic-derived amino acids, taurine, ornithine, and Î³-aminobutyric acid. Since these amino acids have versatile functions including in gut health modulation and brain functions, it can be hypothesized that the dietary prebiotic-digestive enzymes may be beneficial for gut health and brain functions. This study suggests the possibility of applying oil processing by-products in the production of functional food ingredients including bioactive peptides and amino acids.

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Hafiz, Md Abdullah Al, Sherif Tella, Nouha Alcheikh, Hossein Fariborzi e Mohammad I. Younis. "Axially Modulated Clamped-Guided Arch Resonator for Memory and Logic Applications". In ASME 2017 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/detc2017-68284.

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We experimentally demonstrate memory and logic devices based on an axially modulated clamped-guided arch resonator. The device are electrostatically actuated and capacitively sensed, while the resonance frequency modulation is achieved through an axial electrostatic force from the guided side of the clamped-guided arch microbeam. We present two case studies: first, a dynamic memory based on the nonlinear frequency response of the resonator, and second, a reprogrammable two-input logic gate based on the linear frequency modulation of the resonator. These devices show energy cost per memory/logic operation in pJ, are fully compatible with CMOS fabrication processes, have the potential for on-chip system integration, and operate at room temperature.

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Bari, Shahla, Alicia Darwin, Humaira Sarfraz, Lucas Li, Daniel George, Kedar Kirtane, Krupal Patel, Jose R. Conejo-Garcia, Mostafa Eysha e Jameel Muzaffar. "1254 Microbial metabolome as a predictor and modulator of durable response to immune checkpoint therapy in solid cancers". In SITC 39th Annual Meeting (SITC 2024) Abstracts, A1403. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/jitc-2024-sitc2024.1254.

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Relatórios de organizações sobre o assunto "Microbial modulation"

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Zchori-Fein, Einat, Judith K. Brown e Nurit Katzir. Biocomplexity and Selective modulation of whitefly symbiotic composition. United States Department of Agriculture, junho de 2006. http://dx.doi.org/10.32747/2006.7591733.bard.

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Whiteflies are sap-sucking insects that harbor obligatory symbiotic bacteria to fulfill their dietary needs, as well as a facultative microbial community with diverse bacterial species. The sweetpotato whitefly Bemisia tabaci (Gennadius) is a severe agricultural pest in many parts of the world. This speciesconsists of several biotypes that have been distinguished largely on the basis of biochemical or molecular diagnostics, but whose biological significance is still unclear. The original objectives of the project were (i) to identify the specific complement of prokaryotic endosymbionts associated with select, well-studied, biologically and phylogeographically representative biotypes of B. tabaci, and (ii) to attempt to 'cure’ select biotypes of certain symbionts to permit assessment of the affect of curing on whitefly fitness, gene flow, host plant preference, and virus transmission competency.To identify the diversity of bacterial community associated with a suite of phylogeographically-diverseB. tabaci, a total of 107 populations were screened using general Bacteria primers for the 16S rRNA encoding gene in a PCR. Sequence comparisons with the available databases revealed the presence of bacteria classified in the: Proteobacteria (66%), Firmicutes (25.70%), Actinobacteria (3.7%), Chlamydiae (2.75%) and Bacteroidetes (<1%). Among previously identified bacteria, such as the primary symbiont Portiera aleyrodidarum, and the secondary symbionts Hamiltonella, Cardinium and Wolbachia, a Rickettsia sp. was detected for the first time in this insect family. The distribution, transmission, and localization of the Rickettsia were studied using PCR and fluorescence in situ hybridization (FISH). Rickettsia was found in all 20 Israeli B. tabaci populations screened as well as some populations screened in the Arizona laboratory, but not in all individuals within each population. FISH analysis of B. tabaci eggs, nymphs and adults, revealed a unique concentration of Rickettsia around the gut and follicle cells as well as its random distribution in the haemolymph, but absence from the primary symbiont housing cells, the bacteriocytes. Rickettsia vertical transmission on the one hand and its partial within-population infection on the other suggest a phenotype that is advantageous under certain conditions but may be deleterious enough to prevent fixation under others.To test for the possible involvement of Wolbachia and Cardiniumin the reproductive isolation of different B. tabacibiotypes, reciprocal crosses were preformed among populations of the Cardinium-infected, Wolbachia-infected and uninfected populations. The crosses results demonstrated that phylogeographically divergent B. tabaci are reproductively competent and that cytoplasmic incompatibility inducer-bacteria (Wolbachia and Cardinium) both interfered with, and/or rescued CI induced by one another, effectively facilitating bidirectional female offspring production in the latter scenario.This knowledge has implications to multitrophic interactions, gene flow, speciation, fitness, natural enemy interactions, and possibly, host preference and virus transmission. Although extensive and creative attempts undertaken in both laboratories to cure whiteflies of non-primary symbionts have failed, our finding of naturally uninfected individuals have permitted the establishment of Rickettsia-, Wolbachia- and Cardinium-freeB. tabaci lines, which are been employed to address various biological questions, including determining the role of these bacteria in whitefly host biology.

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Weinberg, Zwi G., Adegbola Adesogan, Itzhak Mizrahi, Shlomo Sela, Kwnag Jeong e Diwakar Vyas. effect of selected lactic acid bacteria on the microbial composition and on the survival of pathogens in the rumen in context with their probiotic effects on ruminants. United States Department of Agriculture, janeiro de 2014. http://dx.doi.org/10.32747/2014.7598162.bard.

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This research project was performed in context of the apparent probiotic effect of selected lactic acid bacteria (LAB) silage inoculants on the performance of ruminants (improved feed intake, faster live-weight gain, higher milk yields and improved feed efficiency). The overall objective was to find out how LAB affect ruminant performance. The project included several “chapters” as follows: 1. The effect of LAB silage inoculants on the survival of detrimental bacteria in rumen fluid, in vitro study (Weinberg et al., The Volcani Center). An in vitro model was developed to study the interaction between selected LAB and an E. coli strain tagged with green fluorescence protein (GFP) in buffered RF. Results indicated that both LAB inoculants and E. coli survived in the RF for several days; both LAB inoculants and LAB-treated silages did not affect survival of E. coli in rumen fluid in vitro. The effect of feeding baled wheat silages treated with or without three selected LAB silage inoculants on the performance of high-lactating cows (Weinberg et al., The Volcani Center). Treatments included control (no additive), Lacobacillusbuchneri40788 (LB), Lactobacillus plantarumMTD1 40027 (LP) and Pediococcuspentosaceus30168 (PP), each applied at 10⁶ cfu/g FM. The silages were included in the TMR of 32 high milking Holstein cows in a controlled feeding experiment. All baled silages were of good quality. The LB silage had the numerically highest acetic acid and were the most stable upon aerobic exposure. The cows fed the LB silages had the highest daily milk yields, percent milk fat and protein. The microbiome of baled wheat silages and changes during ensiling of wheat and corn (Sela et al., The Volcani Center). Bacterial community of the baled silages was dominated mainly of two genera in total, dominated by Lactobacillus and Clostridium_sensu_stricto_12 with 300 other genera at very low abundance. Fungal community was composed mainly of two genera in total, dominated by Candida and Monascuswith 20 other genera at very low abundance. In addition, changes in the microbiome during ensiling of wheat and corn with and without addition of L. plantarumMTD1 was studied in mini-silos. Overall 236 bacterial genera were identified in the fresh corn but after 3 months Lactobacillus outnumbered all other species by acquiring 95% of relative abundance. The wheat silage samples are still under analysis. The effect of applying LAB inoculants at ensiling on survival of E. coli O157:H7 in alfalfa and corn silages(Adesogan et al., University of Florida). E. coli (10⁵ cfu/g) was applied to fresh alfalfa and corn at ensiling with or without L. plantarumor L. buchneri. The pathogen was added again after about 3 moths at the beginning of an aerobic exposure period. The inoculants resulted in faster decrease in pH as compared with the control (no additives) or E. coli alone and therefore, the pathogen was eliminated faster from these silages. After aerobic exposure the pathogen was not detected in the LAB treated silages, whereas it was still present in the E. coli alone samples. 5. The effect of feeding corn silage treated with or without L. buchnerion shedding of E. coli O157:H7 by dairy cows (Adesogan et al., UFL). BARD Report - Project 4704 Page 2 of 12 Five hundred cows from the dairy herd of the University of Florida were screened for E. coli shedding, out of which 14 low and 13 high shedders were selected. These cows were fed a total mixed ration (TMR) which was inoculated with E. coli O157:H7 for 21 days. The TMR included corn silage treated with or without L. buchneri. The inoculated silages were more stable upon aerobic exposure than the control silages; the silage inoculant had no significant effect on any milk or cow blood parameters. However, the silage inoculant tended to reduce shedding of E. coli regardless of high or low shedders (p = 0.06). 6. The effect of feeding baled wheat silages treated with or without three selected LAB silage inoculants on the rumen microbiome (Mizrahi et al., BGU). Rumen fluid was sampled throughout the feeding experiment in which inoculated wheat silages were included in the rations. Microbial DNA was subsequently purified from each sample and the 16S rRNA was sequenced, thus obtaining an overview of the microbiome and its dynamic changes for each experimental treatment. We observed an increase in OTU richness in the group which received the baled silage inoculated with Lactobacillus Plantarum(LP). In contrast the group fed Lactobacillus buchneri(LB) inoculated silage resulted in a significant decrease in richness. Lower OTU richness was recently associated in lactating cows with higher performance (Ben Shabatet al., 2016). No significant clustering could be observed between the different inoculation treatments and the control in non metric multi-dimentional scaling, suggesting that the effect of the treatments is not the result of an overall modulation of the microbiome composition but possibly the result of more discrete interactions. Significant phylum level changes in composition also indicates that no broad changes in taxa identity and composition occurred under any treatment A more discrete modulation could be observed in the fold change of several taxonomic groups (genus level analysis), unique to each treatment, before and after the treatment. Of particular interest is the LB treated group, in which several taxa significantly decreased in abundance. BARD Report - Project 4704 Page 3 of 12

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