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Artigos de revistas sobre o tema "Mice"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 21 de setembro de 2024

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1

Park, Woo Teak, e Byeong Cheol Lee. "The conceptual approach of MICE in daily lives: A case of MICE village". Journal & Article Management System 17, n.º 1 (28 de fevereiro de 2021): 225–45. http://dx.doi.org/10.31927/asec.17.1.12.

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2

Tsedenbal, Otgonbayar, e SeungKoo Lee. "Research on MICE Skills and MICE Constraints Affecting MICE Continuous Participation". Korean Journal of Hospitality & Tourism 31, n.º 8 (31 de dezembro de 2022): 101–16. http://dx.doi.org/10.24992/kjht.2022.12.31.08.101.

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3

Seo, Min-Ryeong, Mi-Seong Kim, Yoo-Shik Yoon e Na-Young Baek. "Market Segmentation of MICE Organizer by MICE City Marketing Awareness". Korea Trade Exhibition Review 15, n.º 3 (31 de agosto de 2020): 95–113. http://dx.doi.org/10.16938/ijtfs.2020.15.3.095.

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4

Kim, Eun Cheong, e Jeong Mi Son. "Experimental consideration of MICE frames: Comparison of MICE frames from the perspective of destinations and hosts". Journal & Article Management System 50 (31 de maio de 2023): 45–69. http://dx.doi.org/10.31927/asec.19.2.3.

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5

Šlosárková, S., V. Híbalová, I. Literák, I. Herzig, E. Bártová, P. Kodym e M. Malý. "Experimental toxoplasmosis in hypoiodemic mice". Veterinární Medicína 47, No. 2 - 3 (30 de março de 2012): 67–74. http://dx.doi.org/10.17221/5806-vetmed.

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The hypothesis, that hypoiodemia of goats causes such a compromise of the immune system, which during subsequent Toxoplasma gondii infections results in clinically more pronounced signs of toxoplasmosis, was verifying in laboratory mouse. Hypoiodemic mice (fed by wheat and supplied by water), normoiodemic mice (fed by wheat and supplied by water containing 1.25 mg KI/l) and the majority of standard mice (fed by commercial grain mixture containing 0.83 mg I/kg) were experimentally infected with T. gondii oocysts or tachyzoites. The susceptibility to acute T. gondii infection was evaluated according to mortality rate. As a criterion of cell-mediated immune function has been chosen the spleen-lymphocyte transformation test (LTT). We observed no difference in LTT between hypoiodemic and normoiodemic mice infected with T. gondii oocysts or tachyzoites and no difference in mortality of both infected groups. Four days after the exposure to 100 tachyzoites of T. gondii (K24 strain), all experimentally infected groups of mice showed statistically significant decrease (P = 0.004) in spleen cells responsiveness to stimulation by all mitogens used – as compared to non-infected standard mice group. Reduced responsiveness of cells was probably caused by T. gondii infection itself – the relation to iodine deficiency has not been found.

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6

Wang, Xianmei, Di Tang, Fei Wang, Gaowei Jin, Lifang Wang, Qun Liu e Jing Liu. "Microneme Protein 6 Is Involved in Invasion and Egress by Neospora caninum". Pathogens 10, n.º 2 (13 de fevereiro de 2021): 201. http://dx.doi.org/10.3390/pathogens10020201.

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Background: Neospora caninum, is the etiological agent of neosporosis, an infection that causes abortions in cattle and nervous system dysfunction in dogs. Invasion and egress are the key steps of the pathogenesis of N. caninum infection. Microneme proteins (MICs) play important roles in the recognition, adhesion, and invasion of host cells in other apicomplexan parasites. However, some MICs and their functions in N. caninum infection have rarely been reported. Methods: The homologous recombination strategy was used to investigate the function of MIC6 in N. caninum infection. Results: ΔNcMIC6 showed a smaller plaque size and weakened capacities of invasion and egress than Nc1. Transcription levels of the egress-related genes CDPK1, PLP1, and AMA1 of ΔNcMIC6 were downregulated. Due to the lack of NcMIC6, virulence of the pathogen in the infected mouse was weakened. The subcellular localization of NcMIC1 and NcMIC4 in ΔNcMIC6, however, did not change. Nevertheless, the transcription levels of MIC1 and MIC4 in ΔNcMIC6 were downregulated, and the expression and secretion of MIC1 and MIC4 in ΔNcMIC6 were reduced compared with that in Nc1. Furthermore, the absence of NcMIC6 weakened the virulence in mice and lower parasite load detected in mice brains. Conclusions: NcMIC6 is involved in host cell invasion and egress in N. caninum and may work synergistically with other MICs to regulate the virulence of the pathogen. These data lay a foundation for further research into the function and application of NcMIC6.

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7

Jang, Mi-hwa. "How is Daegu perceived as a MICE destination? A Study on the Placeness of MICE Destination on Social Media". Korea Trade Exhibition Review 16, n.º 1 (31 de março de 2021): 21–39. http://dx.doi.org/10.16938/ijtfs.2021.16.1.021.

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8

Park, Hyo-Yeun, Dong-han Kim e Yeongbae Choe. "Developing MICE Legacy Performance Indicators: Focusing on MICE Integrated Districts". Journal of MICE & Tourism Research 23, n.º 3 (31 de agosto de 2023): 315–32. http://dx.doi.org/10.35176/jmtr.23.3.16.

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9

Mghamis, Munqith Mazin. "Effect of Prenatal Ketamine Exposure on GFAP Marker Expression in Mice Prefrontal Cortex Mice Prefrontal Cortex". International Journal of Psychosocial Rehabilitation 24, n.º 4 (28 de fevereiro de 2020): 3936–44. http://dx.doi.org/10.37200/ijpr/v24i4/pr201507.

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10

Safaeva, Sayyora, e Diyora Adilova. "Mice Tourism: Opportunities, Priorities, Problems, Prospects". American Journal of Applied Sciences 02, n.º 11 (30 de novembro de 2020): 116–21. http://dx.doi.org/10.37547/tajas/volume02issue11-21.

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The MICE sector is one of the most significantly developing tourism industries in recent years. The growth of business tourism strongly affects not only the industry as a whole, but also the economy of the host country. However, with the development and greater popularization of MICE tourism, various difficulties arise. The research work will reveal the main opportunities, prospects and priorities for the development of the MICE tourism industry, as well as analyze the problematic aspects that MICE agencies face when organizing their activities.

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11

Ryu, Jae Hee, e Byeong Cheol Lee. "Conceptualizing MICE Supporters’ Sharing Economy Activity". Journal & Article Management System 14, n.º 1 (28 de fevereiro de 2018): 173–95. http://dx.doi.org/10.31927/asec.14.1.11.

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12

Choi, In-Ho. "Japanese MICE Promotion Utilizing Unique Venues". Korea Trade Exhibition Review 11, n.º 3 (31 de dezembro de 2016): 217–35. http://dx.doi.org/10.16938/ijtfs.2016.11.3.217.

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13

Carreno, Beatriz M., Joel R. Garbow, Grant R. Kolar, Erin N. Jackson, John A. Engelbach, Michelle Becker-Hapak, Leonidas N. Carayannopoulos, David Piwnica-Worms e Gerald P. Linette. "IMMUNE-DEFICIENT MOUSE STRAINS DISPLAY MARKED VARIABILITY IN GROWTH OF HUMAN MELANOMA LUNG METASTASES (88.6)". Journal of Immunology 182, n.º 1_Supplement (1 de abril de 2009): 88.6. http://dx.doi.org/10.4049/jimmunol.182.supp.88.6.

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Abstract Immune-deficient mice are widely used in cancer research to study human cancer biology and evaluate new therapeutics. No comprehensive study has been published documenting differences in human tumor engraftment among immune-deficient strains. Using RhoC-expressing human (A375) melanoma cells, we evaluate scid, NOD-scid (NS), NOD-scid β2mnull (NSB), and NOD-scid IL2Rγnull (NSG) as xenograft tumor recipients. Bioluminescence, magnetic resonance imaging and histopathology were employed to monitor serial tumor growth. Melanoma metastases growth is delayed and variable in scid, and NS mice. In contrast, NSB and NSG mice show rapid tumor engraftment, although tumor growth is variable in NSB mice. NK cells were detected in all strains except NSG, and in vitro activated scid, NS and NSB NK cells kill human melanoma lines and primary melanoma cells. Expression of human NKG2D ligands, MICA and MICB, renders melanoma susceptible to murine NK cell-mediated cytotoxicity and killing is inhibited by antibody blockade of murine NKG2D. Murine NKG2D recognition of MICA/B is an important receptor-ligand interaction employed by NK cells in immune-deficient strains to limit engraftment of human tumors. The absolute NK deficiency in NOD-scid IL2Rγnull animals makes this strain an excellent recipient of melanoma and potentially other human malignancies.

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14

Кузнецова, Ольга, Olga Kuznetsova, Людмила Сильчева, Lyudmila Silcheva, Елена Масленникова, Elena Maslennikova, Дина Макеева e Dina Makeeva. "Aspects on MICE-tourism and its management". Services in Russia and abroad 8, n.º 2 (21 de abril de 2014): 40–52. http://dx.doi.org/10.12737/3585.

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The article highlights the issues of MICE-related business travel, such as business tourism, conference-, exhibition- and travel-study tourism. The authors consider the historical preconditions for business travel birth and development, as well as the peculiarities of incentive tourism and the types and purposes of incentive programmes. The article provides statistics concerning the current state of the MICE-industry, and a comprehensive aspect-by-aspect study of a sample offsite seminar management in the framework of business tourism.

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15

Vardakis, Lazaros, Yiannis Michailidis, Panagiotis Topalidis, Charalambos Zelenitsas, Athanasios Mandroukas, Ioannis Gissis, Kosmas Christoulas, George Mavrommatis e Thomas Metaxas. "Application of a Structured Training Plan on Different-Length Microcycles in Soccer—Internal and External Load Analysis between Training Weeks and Games". Applied Sciences 13, n.º 12 (8 de junho de 2023): 6935. http://dx.doi.org/10.3390/app13126935.

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The aim of this study was to apply a training plan to four different-length microcycles (MIC) in soccer and analyze (a) the load within the training weeks and (b) the short-term effect on the matches that were played at the end of each microcycle. An intervention training program applied to microcycles of five, six, seven and nine days during two seasons of the Cypriot Fist Division. The GPS technology and subjective (wellness, RPE) assessments were used to monitor the load throughout trainings and games. In weekly external load, there were differences between the four microcycles, with a lower load in MIC5 for all the parameters and higher on MIC9 in the most of them (p < 0.05). In RPE, MIC9 (229 ± 60 arbitrary units (au)) differed significantly from MIC5 (229 ± 60 au, p < 0.001), MIC6 (281 ± 67 au; p < 0.001) and MIC7 (297 ± 48 au, p = 0.009). MIC5 also differed from MIC6 (p = 0.001) and MIC7 (p < 0.001). In the game external load, the only differences found in GDEC2 (game decelerations) were between MIC7 (68 ± 10 number (n)), MIC5 (61 ± 11 n, p = 0.035) and MIC6 (60 ± 10 n, p = 0.002); in GSPEF (game speed efforts), between MIC5 (40 ± 17 n), MIC7 (48 ± 14 n, p = 0.004) and MIC9 (48 ± 16 n, p < 0.001) and between MIC6 (41 ± 14 n), MIC7 (p = 0.009), and MIC9 (p = 0.009); in GMPW5 (game metabolic power efforts), between MIC7 (1307 ± 271 n), MIC5 (1201 ± 340 n, p = 0.035) and MIC6 (1178 ± 261 n, p = 0.001). No differences were found for wellness and perceived exertion. It is important for performance coaches to adapt the training load to the length of the microcycle, applying a lower load to short training weeks and manage the load fluctuation on long training weeks in terms of volume, intensity and recovery. In our study, the results confirmed that this strategy could result in similar performance in the games, regardless of microcycle length.

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16

Kang, Hae-Sang, e Kang-Young Song. "Analysis on the Satisfaction by MICE Participants in Busan Metropolitan". Journal of the Korea Contents Association 10, n.º 11 (28 de novembro de 2010): 414–23. http://dx.doi.org/10.5392/jkca.2010.10.11.414.

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17

Shakya, Pratibha, Neelesh Kumar Shakya e C. Mohanty. "VALPROATE INDUCED NEPHROTOXICITY ON FETAL MICE KIDNEY". International Journal of Anatomy and Research 8, n.º 1.3 (5 de março de 2020): 7383–85. http://dx.doi.org/10.16965/ijar.2020.108.

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18

Kim, Chul-Won, e Ji-Yeon Park. "A Study on Exploratory Paradigm for the MICE Serviceology". Korea Trade Exhibition Review 10, n.º 1 (30 de abril de 2015): 1–20. http://dx.doi.org/10.16938/ijtfs.2015.10.1.001.

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19

Bléry, Mathieu, Manel Mrabet-Kraiem, Ariane Morel, Florence Lhospice, Delphine Bregeon, Cécile Bonnafous, Laurent Gauthier et al. "Targeting MICA/B with cytotoxic therapeutic antibodies leads to tumor control". Open Research Europe 1 (27 de outubro de 2021): 107. http://dx.doi.org/10.12688/openreseurope.13314.2.

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Background: MICA and MICB are tightly regulated stress-induced proteins that trigger the immune system by binding to the activating receptor NKG2D on cytotoxic lymphocytes. MICA and MICB are highly polymorphic molecules with prevalent expression on several types of solid tumors and limited expression in normal/healthy tissues, making them attractive targets for therapeutic intervention. Methods: We have generated a series of anti-MICA and MICB cross-reactive antibodies with the unique feature of binding to the most prevalent isoforms of both these molecules. Results: The anti-MICA and MICB antibody MICAB1, a human IgG1 Fc-engineered monoclonal antibody (mAb), displayed potent antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) of MICA/B-expressing tumor cells in vitro. However, it showed insufficient efficiency against solid tumors in vivo, which prompted the development of antibody-drug conjugates (ADC). Indeed, optimal tumor control was achieved with MICAB1-ADC format in several solid tumor models, including patient-derived xenografts (PDX) and carcinogen-induced tumors in immunocompetent MICAgen transgenic mice. Conclusions: These data indicate that MICA and MICB are promising targets for cytotoxic immunotherapy.

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20

Bléry, Mathieu, Manel Mrabet-Kraiem, Ariane Morel, Florence Lhospice, Delphine Bregeon, Cécile Bonnafous, Laurent Gauthier et al. "Targeting MICA/B with cytotoxic therapeutic antibodies leads to tumor control". Open Research Europe 1 (13 de setembro de 2021): 107. http://dx.doi.org/10.12688/openreseurope.13314.1.

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Background: MICA and MICB are tightly regulated stress-induced proteins that trigger the immune system by binding to the activating receptor NKG2D on cytotoxic lymphocytes. MICA and MICB are highly polymorphic molecules with prevalent expression on several types of solid tumors and limited expression in normal/healthy tissues, making them attractive targets for therapeutic intervention. Methods: We have generated a series of anti-MICA and MICB cross-reactive antibodies with the unique feature of binding to the most prevalent isoforms of both these molecules. Results: The anti-MICA and MICB antibody MICAB1, a human IgG1 Fc-engineered monoclonal antibody (mAb), displayed potent antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) of MICA/B-expressing tumor cells in vitro. However, it showed insufficient efficiency against solid tumors in vivo, which prompted the development of antibody-drug conjugates (ADC). Indeed, optimal tumor control was achieved with MICAB1-ADC format in several solid tumor models, including patient-derived xenografts (PDX) and carcinogen-induced tumors in immunocompetent MICAgen transgenic mice. Conclusions: These data indicate that MICA and MICB are promising targets for cytotoxic immunotherapy.

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21

Hester, James, Jeremi Mullins, Qila Sa, Laura Payne, Corinne Mercier, Marie-France Cesbron-Delauw e Yasuhiro Suzuki. "Toxoplasma gondii Antigens Recognized by IgG Antibodies Differ between Mice with and without Active Proliferation of Tachyzoites in the Brain during the Chronic Stage of Infection". Infection and Immunity 80, n.º 10 (30 de julho de 2012): 3611–20. http://dx.doi.org/10.1128/iai.00604-12.

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ABSTRACTWe examined whether tachyzoite proliferation in the brains of immunocompetent hosts during the chronic stage of infection withToxoplasma gondiiinduces production of IgG antibodies that recognize parasite antigens different from those recognized by the antibodies of infected hosts that do not have tachyzoite growth. For this purpose, two groups of CBA/J mice, which display continuous tachyzoite growth in their brains during the later stage of infection, were infected, and one group received treatment with sulfadiazine to prevent tachyzoite proliferation during the chronic stage of infection.T. gondiiantigens recognized by the IgG antibodies from these two groups of mice were compared using immunoblotting following separation of tachyzoite antigens by two-dimensional gel electrophoresis. Several antigens, including the microneme protein MIC2, the cyst matrix protein MAG1, and the dense granule proteins GRA4 and GRA7, were commonly recognized by IgG antibodies from both groups of mice. There were multiple antigens recognized mostly by IgG antibodies of only one group of mice, either with or without cerebral tachyzoite growth. The antigens recognized only by or mostly by the antibodies of mice with cerebral tachyzoite growth include MIC6, the rhoptry protein ROP1, GRA2, one heat shock protein HSP90, one (putative) HSP70, and the myosin heavy chain. These results indicate that levels of IgG antibody to only selectedT. gondiiantigens increase in association with cerebral tachyzoite proliferation (reactivation of infection) in immunocompetent hosts with chronic infection.

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22

Shen, Mengdie, Bibi Zhang, Mengyao Wang, Li’na Meng e Bin Lv. "Mica Can Alleviate TNBS-Induced Colitis in Mice by Reducing Angiotensin II and IL-17A and Increasing Angiotensin-Converting Enzyme 2, Angiotensin 1-7, and IL-10". Mediators of Inflammation 2020 (10 de outubro de 2020): 1–8. http://dx.doi.org/10.1155/2020/3070345.

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Aim. To explore the treatment effect of mica on 2,4,6-trinitrobenzenesulfonic acid solution- (TNBS-) induced colitis in mice. Materials and Methods. Thirty male BALB/C mice were randomly divided into the control group, the TNBS group, and the mica group. Control mice were treated with saline solution. Experimental colitis was induced by TNBS (250 mg/kg/d) in the TNBS group and the mica group. After modeling, the mica group was treated with mica (180 mg/kg/d) for 3 days, while the TNBS group continued the treatment with TNBS. All solutions were injected intrarectally. During treatment, body weight and mice activity were monitored daily. After treatment, the colon tissues of mice were collected; angiotensin II (Ang II), angiotensin-converting enzyme 2 (ACE2), angiotensin 1-7 (Ang (1-7)), IL-17A, and IL-10 expression was analyzed by ELISA and immunohistochemistry. Results. Food intake, activity, and body weight gradually decreased in the TNBS group compared to the control group and the mica group (all P<0.05). Also, black stool adhesion in the anus and thin and bloody stool were observed in the TNBS group, but not in the other two groups. Moreover, the expression of Ang II, ACE2, Ang (1-7), IL-17A, and IL-10 in the TNBS group increased compared to that in the control group. Compared to the TNBS group, ACE2, Ang (1-7), and IL-10 in the mica group increased, while Ang II and IL-17A decreased (all P<0.05). Conclusion. Mica can alleviate TNBS-induced colitis in mice by regulating the inflammation process; it reduces Ang II and IL-17A and increases ACE2, IL-10, and Ang (1-7).

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23

Dhar, Payal, Fahmin Basher, Jinyu Zhang e Jennifer Wu. "Modulation of signaling preference of NK cells by different forms of NKG2D ligands and its implications". Journal of Immunology 198, n.º 1_Supplement (1 de maio de 2017): 130.27. http://dx.doi.org/10.4049/jimmunol.198.supp.130.27.

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Abstract The significance of ligand-induced activation of NK cell activating receptor NKG2D has been well established in controlling tumor growth in various experimental animal models. Amongst different types of NKG2D ligands, MHC I chain related molecule MICA/B is expressed most prevalently in various human cancers. In particular, proteolytically shed form of MICA/B (sMIC) has been shown to suppress the immune system and found to correlate with advanced disease stages in cancer patients. Previous studies in our lab using two humanized bi-transgenic mice, one expressing native ligand (TRAMP/MICB) and the other expressing the shedding-resistant mutant (TRAMP/MICB.A2) revealed opposite roles of these ligands in regulating tumor immunity. MICB expressing mice exhibited increased tumor progression, whereas MICB.A2 expressing mice had tumor free survival. These findings raised the intriguing question of why do these structurally similar forms of MIC have vastly different effects on tumor immunity. To address this question, we investigated the signaling events and functional outcomes in NK cells upon stimulation by the two forms of ligands. In vitro co-culture studies of NK cells with tumor cell lines expressing sMICB and MICB.A2 revealed elevated pro-inflammatory and immunosuppressive cytokine production by NK cells upon stimulation with sMICB. In contrast, NK cells stimulated with MICB.A2 displayed enhanced expression of cytotoxicity mediators and signaling molecules of cytotoxicity pathway. This suggests that signaling through sMICB may polarize the NKG2D signaling pathways with preferential activation of inflammatory cytokine pathways. Our data has uncovered a new potential mechanism whereby sMIC promotes tumor progression.

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24

Ha, Myung hee, e Chul Won Kim. "A Study on the Development of the Network Governance Model - Focusing on Seoul MICE Industry -". Journal & Article Management System 14, n.º 1 (30 de novembro de 2018): 23–45. http://dx.doi.org/10.31927/asec.14.4.2.

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Arévalo Rodríguez, Montserrat, Montserrat Civit Torruella e Maria Antònia Martí. "MICE". International Journal of Corpus Linguistics 9, n.º 1 (29 de abril de 2004): 53–68. http://dx.doi.org/10.1075/ijcl.9.1.03are.

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In the field of corpus linguistics, Named Entity treatment includes the recognition and classification of different types of discursive elements like proper names, date, time, etc. These discursive elements play an important role in different Natural Language Processing applications and techniques such as Information Retrieval, Information Extraction, translations memories, document routers, etc.

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Heller, Stefan, e A. J. Hudspeth. "Two deaf mice, two deaf mice…". Nature Medicine 4, n.º 5 (maio de 1998): 560–61. http://dx.doi.org/10.1038/nm0598-560.

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Bourguin, Isabelle, Muriel Moser, Dominique Buzoni-Gatel, Françoise Tielemans, Daniel Bout, Jacques Urbain e Oberdan Leo. "Murine Dendritic Cells Pulsed In Vitro withToxoplasma gondii Antigens Induce Protective Immunity In Vivo". Infection and Immunity 66, n.º 10 (1 de outubro de 1998): 4867–74. http://dx.doi.org/10.1128/iai.66.10.4867-4874.1998.

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ABSTRACT The activation of a predominant T-helper-cell subset plays a critical role in disease resolution. In the case of Toxoplasma gondii, the available evidence indicates that CD4+protective cells belong to the Th1 subset. The aim of this study was to determine whether T. gondii antigens (in T. gondii sonicate [TSo]) presented by splenic dendritic cells (DC) were able to induce a specific immune response in vivo and to protect CBA/J mice orally challenged with T. gondiicysts. CBA/J mice immunized with TSo-pulsed DC exhibited significantly fewer cysts in their brains after oral infection with T. gondii 76K than control mice did. Protected mice developed a strong humoral response in vivo, with especially high levels of anti-TSo immunoglobulin G2a antibodies in serum. T. gondii antigens such as SAG1 (surface protein), SAG2 (surface protein), MIC1 (microneme protein), ROP2 through ROP4 (rhoptry proteins), and MIC2 (microneme protein) were recognized predominantly. Furthermore, DC loaded with TSo, which synthesized high levels of interleukin-12 (IL-12), triggered a strong cellular response in vivo, as assessed by the proliferation of lymph node cells in response to TSo restimulation in vitro. Cellular proliferation was associated with gamma interferon and IL-2 production. Taken together, these results indicate that immunization of CBA/J mice with TSo-pulsed DC can induce both humoral and Th1-like cellular immune responses and affords partial resistance against the establishment of chronic toxoplasmosis.

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Kim, Seokyung, Yooshik Yoon, Miseong Kim e Yoonjung Kim. "The Study of the MICE Brand Equity and Brand Loyalty by Creating Shared Value in MICE Industry". Journal of Tourism Management Research 22, n.º 5 (30 de setembro de 2018): 69–88. http://dx.doi.org/10.18604/tmro.2018.22.5.4.

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Tsedenbal, Otgonbayar, Seung Koo Lee e Kyung-A. Lee. "The Influence of MICE Skills on Selection Attributes, Participation Constraints, and Participation Satisfaction : Focused on MICE Participants". Journal of Tourism Enhancement 11 (31 de janeiro de 2023): 39–57. http://dx.doi.org/10.35498/kotes.2023.se1.39.

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Trisetiyono, Yuli, Widjiati Widjiati, Syarief Thaufik Hidayat e Noor Pramono. "Antioxidant Herbs Supplementation Inhibits Endometriosis Extension in Mice". Journal of Biomedicine and Translational Research 5, n.º 2 (15 de outubro de 2019): 53–61. http://dx.doi.org/10.14710/jbtr.v5i2.4716.

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Background: Increased oxidative stress causes inflammation and increases angiogenesis. It presumed to promote the proliferation of endometriosis tissue. Kebar grass (Biophytum petersianum) and other herbs such as green tea and Cucumis melo, which contain high antioxidants, are expected to decrease oxidative stress, inflammation, angiogenesis, and reduced endometriosis implants.Objective: To investigate the effects of Kebar grass, green tea, and Cucumis melo to malondialdehyde serum, tumor necrosis factor alpha, and vascular endothelial growth factor expression, and the area of the endometriotic implants.Methods: Twenty-eight mice were divided into four groups, i.e., the first group of endometriosis mice was given Kebar grass extract; the second group was assigned green tea extract, the third group was given the combination of Cucumis melo extract–gliadin, and the last containing the untreated endometriosis mice as the control. Each treatment was given for 14 days. The data of MDA serum level, the area of the endometriotic implants, TNF-α, and VEGF expression were collected and analyzed.Results: The MDA serum levels of the groups treated with Kebar grass extract, green tea extract, and Cucumis melo extract – gliadin were significantly lower (p=0.001) than the control group. TNF-α expression of the groups provided with each treatment also lower than the control groups (p=0.002). However, only the administration of the Cucumis melo extract–gliadin resulted in lower VEGF expression compare with the control (p=0.017). Finally, the area of the endometriotic implants of the mice models administered with each treatment was smaller than the control group (p=0.003).Conclusion: Kebar grass as well as green tea and Cucumis melo–gliadin inhibits endometriotic implants extension by decreasing MDA serum and TNF-α expression.

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Vohra, Prerna, e Navneet Kumar Gupta. "Carbontetrachloride induced toxicity in liver of albino mice". Indian Journal of Applied Research 3, n.º 9 (1 de outubro de 2011): 273–75. http://dx.doi.org/10.15373/2249555x/sept2013/80.

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Mustafa, Snoor Jalal, e Kameel Mate Naoum. "EFFECT OF ACYCLOVIR ON EMBRYO IMPLANTATION IN MICE". Journal of Sulaimani Medical College 3, n.º 2 (1 de dezembro de 2013): 103–7. http://dx.doi.org/10.17656/jsmc.10038.

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Masopust, David, Christine P. Sivula e Stephen C. Jameson. "Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology". Journal of Immunology 199, n.º 2 (10 de julho de 2017): 383–88. http://dx.doi.org/10.4049/jimmunol.1700453.

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Kim, Jun-Hyun, Bong-Seok Kim e Ji-Yeon Lee. "A Study on Determinants of Burnout of MICE Industry Workers". Korea Trade Exhibition Review 16, n.º 1 (31 de março de 2021): 131–56. http://dx.doi.org/10.16938/ijtfs.2021.16.1.131.

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Kim, Mi-Seong, e Hwa-Sung Song. "Finding the ways to strengthen competitiveness of public MICE metaverse". Korea Trade Exhibition Review 18, n.º 3 (30 de setembro de 2023): 69–88. http://dx.doi.org/10.16938/ijtfs.2023.06.3.069.

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Park, Hyo-Yeun. "The Study on Improvements of Statistics in the MICE Industry: Focused on『MICE Industry Statistics Survey』". Journal of MICE & Tourism Research 20, n.º 3 (30 de setembro de 2020): 253–68. http://dx.doi.org/10.35176/jmtr.20.3.13.

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Yan, Hai-Kuo, Zi-Guo Yuan, Hui-Qun Song, Eskild Petersen, Yang Zhou, Di Ren, Dong-Hui Zhou et al. "Vaccination with a DNA Vaccine Coding for Perforin-Like Protein 1 and MIC6 Induces Significant Protective Immunity against Toxoplasma gondii". Clinical and Vaccine Immunology 19, n.º 5 (29 de fevereiro de 2012): 684–89. http://dx.doi.org/10.1128/cvi.05578-11.

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ABSTRACTHost cell invasion byToxoplasma gondiiis tightly related to microneme protein 6 (MIC6) andT. gondiiperforin-like protein 1 (TgPLP1). In this study, we constructed a DNA vaccine expressing a TgPLP1/MIC6 fusion protein using the pIRESneo vector, and we evaluated the immune response induced by this vaccine in Kunming mice. Levels of IgG antibody, gamma interferon (IFN-γ), interleukin 2 (IL-2), IL-12, IL-4, and IL-10 were examined. Five mice were chosen randomly from every group (vaccinated groups or the nonvaccinated control group) and were challenged intragastrically with 80 cysts ofT. gondiistrain PRU (genotype II) in order to observe mortality daily. To analyze protection against a less-virulent challenge, eight mice of each group were orally infected with 20 cysts of strain PRU at the 14th day after the last immunization. The brain parasite load was evaluated 6 weeks after infection. The results demonstrated that immunization with pIRESneo/MIC6/PLP1 resulted in the lowest brain cyst count and prolonged the survival time of immunized mice. The levels ofToxoplasma-specific IgG, IFN-γ, IL-2, and IL-12 increased significantly, and the numbers of cysts in brains decreased more obviously, in the group immunized with plasmid pIRESneo/MIC6/PLP1 than in the other groups (P< 0.05). Compared with pIRESneo/MIC6/PLP1, coimmunization with pIRESneo/MIC6/PLP1 and adjuvant murine IL-18 promoted cellular and humoral immune responses but did not contribute significantly to cyst reduction (65.43% versus 61.60%) or the survival of immunized mice (45.0 ± 2.9 days versus 42.8 ± 2.9 days) (P> 0.05). Furthermore, the study also showed that the immune efficacy induced by pIRESneo/MIC6/PLP1 was better than that induced by pVAX/PLP1 or pVAX/MIC6 alone.

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Cherif H.S, Cherif H. S., Saidi F. Saidi F e Guedioura A. Guedioura A. "Toxicological evaluation of Aristolochia longa L. extract in mice". Indian Journal of Applied Research 4, n.º 5 (1 de outubro de 2011): 26–30. http://dx.doi.org/10.15373/2249555x/may2014/8.

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KUMAR, DEEPAK, e SURESH KUMAR. "Neuropharmacological Activities of Abies pindrow Aerial Parts in Mice". JOURNAL OF PHARMACEUTICAL TECHNOLOGY, RESEARCH AND MANAGEMENT 3, n.º 2 (2 de novembro de 2015): 141–51. http://dx.doi.org/10.15415/jptrm.2015.32011.

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DHINGRA, D., e S. PARSHAD. "Improvement of Learning and Memory of Mice by Plumbagin". Journal of Pharmaceutical Technology, Research and Management 4, n.º 2 (1 de novembro de 2016): 147–59. http://dx.doi.org/10.15415/jptrm.2016.42010.

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Parashar, Vivek, Buddhadeb Ghosh, Natwar lal Gaur, Satya Narayan Shamal, S. K. Pandey e Girdhari Lal Shah. "TERATOLOGICAL EFFECTS OF CARBOPLATIN: A MORPHOLOGICAL STUDY IN MICE". International Journal of Anatomy and Research 4, n.º 2.2 (31 de maio de 2016): 2358–64. http://dx.doi.org/10.16965/ijar.2016.218.

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Ha, Myungehee, e Chulwon Kim. "Directing the Revision of Local Governments’ MICE-related Ordinances". Korea Trade Exhibition Review 15, n.º 4 (30 de setembro de 2020): 81–103. http://dx.doi.org/10.16938/ijtfs.2020.15.4.081.

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Travis, John. "Model Mice". Science News 164, n.º 24 (13 de dezembro de 2003): 371. http://dx.doi.org/10.2307/4019057.

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Warren, Noah. "Wall Mice". Ploughshares 46, n.º 4 (2020): 167–68. http://dx.doi.org/10.1353/plo.2020.0176.

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BABINET, CHARLES. "Transgenic Mice". Journal of the American Society of Nephrology 11, suppl 2 (novembro de 2000): S88—S94. http://dx.doi.org/10.1681/asn.v11suppl_2s88.

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Abstract. Stable integration into the mouse genome of exogenous genetic information, i.e., the creation of transgenic mice, has become a privileged way of analyzing gene function in normal development and pathology. Both gene addition and gene replacement may be performed. This has allowed, in particular, the creation of mice in which precise mutations are introduced into a given gene. Furthermore, in recent years, strategies that induce the expression of a mutation in a given type of cell and/or at a given time in development have been developed. Thus, the transgenic methodology affords a unique and irreplaceable tool for the study of mammalian development and biology and for the creation of animal models for human genetic diseases.

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Jensen, Ronald, Ernest Schimmerling, Ralf Schindler e John Steel. "Stacking mice". Journal of Symbolic Logic 74, n.º 1 (março de 2009): 315–35. http://dx.doi.org/10.2178/jsl/1231082314.

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AbstractWe show that either of the following hypotheses imply that there is an inner model with a proper class of strong cardinals and a proper class of Woodin cardinals. 1) There is a countably closed cardinal κ ≥ ℵ such that □κ and □(κ) fail. 2) There is a cardinal κ such that κ is weakly compact in the generic extension by Col(κ, κ+). Of special interest is 1) with κ = ℵ3 since it follows from PFA by theorems of Todorcevic and Velickovic. Our main new technical result, which is due to the first author, is a weak covering theorem for the model obtained by stacking mice over Kc∥κ.

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Cheng, J. J., e W. S. Anderson. "Drowsy Mice". Neurosurgery 70, n.º 2 (fevereiro de 2012): N18—N19. http://dx.doi.org/10.1227/01.neu.0000410936.61699.88.

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Rusk, Nicole. "Human mice". Nature Methods 4, n.º 3 (março de 2007): 197. http://dx.doi.org/10.1038/nmeth0307-196b.

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Macchiarini, Francesca, Markus G. Manz, A. Karolina Palucka e Leonard D. Shultz. "Humanized mice". Journal of Experimental Medicine 202, n.º 10 (21 de novembro de 2005): 1307–11. http://dx.doi.org/10.1084/jem.20051547.

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Animal models have been instrumental in increasing the understanding of human physiology, particularly immunity. However, these animal models have been limited by practical considerations and genetic diversity. The creation of humanized mice that carry partial or complete human physiological systems may help overcome these obstacles. The National Institute of Allergy and Infectious Diseases convened a workshop on humanized mouse models for immunity in Bethesda, MD, on June 13–14, 2005, during which researchers discussed the benefits and limitations of existing animal models and offered insights into the development of future humanized mouse models.

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LeBrasseur, Nicole. "Titinless mice". Journal of Cell Biology 173, n.º 4 (15 de maio de 2006): 455b. http://dx.doi.org/10.1083/jcb.1734iti3.

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