Bibliografias temáticas / Medicine safety

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Literatura científica selecionada sobre o tema "Medicine safety"

Autor: Grafiati

Publicado: 21 de dezembro de 2024

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Artigos de revistas sobre o assunto "Medicine safety"

Bensoussan, Alan. "Herbal medicine safety". Medical Journal of Australia 183, n.º 11-12 (25 de novembro de 2005): 663. http://dx.doi.org/10.5694/j.1326-5377.2005.tb00031.x.

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Frassica, Frank J. "Safety in Medicine". Orthopedics 26, n.º 11 (novembro de 2003): 1100–1114. http://dx.doi.org/10.3928/0147-7447-20031101-05.

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Ruiqi Luo, Ruiqi Luo, e Luo Zhong Ruiqi Luo. "Medicine Safety Assessment Method based on Dynamic Dual Optimization". 網際網路技術學刊 23, n.º 3 (maio de 2022): 611–19. http://dx.doi.org/10.53106/160792642022052303019.

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<p>As people pay more and more attention to medicine safety issues, related medicine safety monitoring platforms are also rapidly popularized. However, previous work has poor accuracy and low efficiency in medicine safety assessment. In this paper, the medicine safety evaluation index system of the medicine safety monitoring platform is determined from four aspects: medicine research and development, medicine market, medicine production, and medicine uses. In order to solve the problems of the medicine safety evaluation model, such as low evaluation accuracy, slow convergence speed, and long training time, the dynamic dual optimization of PSO-BP medicine safety assessment method (OPSO-BP) is proposed. The weights and thresholds of BP neural network are optimized by the PSO algorithm to improve the quality of assessment. In addition, we optimize PSO: use the cosine function to dynamically adjust the inertia weight w and use the average optimal position of the individual in the population to replace the optimal position of the individual. It improves the problem that the evaluation model in the traditional algorithm is easy to fall into the local optimal solution due to the lack of generalization ability. In this paper, the effectiveness of OPSO-BP is verified by comparative experiments with the designed questionnaire data of medicine safety evaluation.</p> <p> </p>

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Jain, Sachin Kumar. "Standardization & Safety Measures: Quality-Based Validation of Herbal Medicine". International Journal of Pharmacognosy & Chinese Medicine 3, n.º 4 (2019): 1–3. http://dx.doi.org/10.23880/ipcm-16000182.

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Herbal medicines magnetize the curiosity of both patients and scientists, in all aspects of drug development from natural products and also for rationale of traditional medicine (TM). Numerous developing countries rely on TM because of their convenience and affordability, and scientists all over the world believe medicinal plants as a resource of new chemical entities and use them to isolate compounds such as Sennoside, quinine, strychnine, digoxin, morphine, taxol, atropine, and vinblastine

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Kadetz, Paul. "Safety Net—The Construction of Biomedical Safety in the Global ‘Traditional Medicine’ Discourse". Asian Medicine 10, n.º 1-2 (3 de outubro de 2015): 121–51. http://dx.doi.org/10.1163/15734218-12341348.

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This paper examines the social construction of the World Health Organization’s normative discourse of the safety of ‘traditional medicines’. The findings presented are based on archival research, a review of the literature, discourse analysis of who documents, semi-structured interviews with pertinent stakeholders, and participant experience at the Western Pacific Region Office of the who. This discourse of safety can be traced to the rise and global dominance of scientific medicine over plural health care and the construction of biomedical expertise. This paper argues that biomedicine’s global hegemony and construction of a dominant discourse of safety was, at least in part, influenced by the American Medical Association, The Flexner Report, The Rockefeller Foundation, the League of Nations Health Organization, the World Health Organization, and the who’s adoption of traditional Chinese medicine as a template for health care integration. This network of stakeholders influenced the construction and dissemination of the global biomedical discourse of safety and the purported ‘safe’ control, regulation, and integration of non-biomedical practices and practitioners via biomedical expertise.

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Saad, Bashar, Hassan Azaizeh, Ghassan Abu-Hijleh e Omar Said. "Safety of Traditional Arab Herbal Medicine". Evidence-Based Complementary and Alternative Medicine 3, n.º 4 (2006): 433–39. http://dx.doi.org/10.1093/ecam/nel058.

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Herbal remedies are widely used for the treatment and prevention of various diseases and often contain highly active pharmacological compounds. Many medicinal herbs and pharmaceutical drugs are therapeutic at one dose and toxic at another. Toxicity related to traditional medicines is becoming more widely recognized as these remedies become popular in the Mediterranean region as well as worldwide. Most reports concerning the toxic effects of herbal medicines are associated with hepatotoxicity although reports of other toxic effects including kidney, nervous system, blood, cardiovascular and dermatologic effects, mutagenicity and carcinogenicity have also been published in the medical literature. This article presents a systematic review on safety of traditional Arab medicine and the contribution of Arab scholars to toxicology. Use of modern cell biological, biochemical,in vitroandin vivotechniques for the evaluation of medicinal plants safety is also discussed.

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Jonas, Wayne B. "Safety in complementary medicine". Complementary Therapies in Medicine 4, n.º 2 (abril de 1996): 141–42. http://dx.doi.org/10.1016/s0965-2299(96)80035-5.

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Dodd, Roger, W. Kurt Roth, Paul Ashford, Elizabeth M. Dax e Girish Vyas. "Transfusion medicine and safety". Biologicals 37, n.º 2 (abril de 2009): 62–70. http://dx.doi.org/10.1016/j.biologicals.2009.01.006.

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Li, Lu, Ping Chung Leung, Tony Kwok Hung Chung e Chi Chiu Wang. "Systematic Review of Chinese Medicine for Miscarriage during Early Pregnancy". Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–16. http://dx.doi.org/10.1155/2014/753856.

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Background. Miscarriage is a very common complication during early pregnancy. So far, clinical therapies have limitation in preventing the early pregnancy loss. Chinese Medicine, regarded as gentle, effective, and safe, has become popular and common as a complementary and alternative treatment for miscarriages. However, the evidence to support its therapeutic efficacy and safety is still very limited.Objectives and Methods. To summarize the clinical application of Chinese Medicine for pregnancy and provide scientific evidence on the efficacy and safety of Chinese medicines for miscarriage, we located all the relevant pieces of literature on the clinical applications of Chinese Medicine for miscarriage and worked out this systematic review.Results. 339,792 pieces of literature were identified, but no placebo was included and only few studies were selected for systematic review and conducted for meta-analysis. A combination of Chinese medicines and Western medicines was more effective than Chinese medicines alone. No specific safety problem was reported, but potential adverse events by certain medicines were identified.Conclusions. Studies vary considerably in design, interventions, and outcome measures; therefore conclusive results remain elusive. Large scales of randomized controlled trials and more scientific evidences are still necessary to confirm the efficacy and safety of Chinese medicines during early pregnancy.

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Alotaibi, Majed H. "Medication Safety". Journal of Medical Science And clinical Research 11, n.º 06 (30 de junho de 2023): 111–13. http://dx.doi.org/10.18535/jmscr/v11i6.21.

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Drug therapy is the most common healing mediation in medicine to recover patient well-being. In spite of the concentrating to help patients, there are numerous examples of inappropriate medication procedures and practices that compromise drug efficacy and lead to preventable medication errors, thereby jeopardizing patient health. Insecure medication practices leading to medication errors are one of the leading reasons of healthcare-related illness and mortality that globally published drug safety fact files. Understanding these characteristic risks will allow healthcare suppliers to better manage drawbacks and efforts to guarantee drug security in healthcare delivery. When safety policies and risk organization skills are integrated into health methods and medication rehearses, safer hospitals and main care can be achieved. Safety and danger management are integrated into healthcare arrangements and processes

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Teses / dissertações sobre o assunto "Medicine safety"

Mabunda, Hitekani Tolerance. "Innovator Medicines Versus Generic Medicine Package Inserts Safety Amendments, the Reality in South Africa". University of the Western Cape, 2017. http://hdl.handle.net/11394/6317.

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Magister Scientiae - MSc (Pharmacy Administration and Policy Regulation)
Availability of clinically relevant and unbiased medicine information goes a long way in promoting rational use of medicines. The package insert (PI) is one of the sources of information utilised by healthcare professionals for accessing relevant medicine information such as indications, contra-indications and special precautions (Singh, Mohan, Kumar, & Gupta,2016). It is important that the PI contains updated safety information. The safety information in the PIs of the innovator and generic medicines are expected to be the similar since they contain the same active ingredients. Generic medicines have the same efficacy and safety as innovator medicines and are considered bioequivalent. Generic medicines are interchangeable with innovator medicines.

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Thornborrow-Geswind, Kirsten. "Evaluation of medicine safety reporting systems in South Africa". Thesis, Nelson Mandela Metropolitan University, 2017. http://hdl.handle.net/10948/21439.

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Pharmacovigilance is “the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem”. To date, no comprehensive study has been performed to evaluate the pharmacovigilance system in the public health sector in South Africa. The primary aim of this study was to evaluate the current status of pharmacovigilance systems within the public healthcare sector in South Africa, and the level of functioning of these systems, in order to provide relevant recommendations, where necessary, for improvement, using the Indicator-based Pharmacogivilance Assessment Tool (IPAT). National and provincial entities were deemed compulsory (n=14), while facilities were selected via random, stratified sampling to obtain a representation at each facility level (n=101). The IPAT was amended for relevance at each level of data collection. Indicators are classified as core and supplementary and compliance with core indicators shows the level of functioning National entities obtained an IPAT score of 36 out of a maximum of 72, achieving 50% compliance. Province D and Province G obtained overall IPAT scores of 29 and 12 respectively out of a maximum of 40, achieving an overall 72.5% and 30% compliance respectively Results at provincial and facility levels were not fully representative due to a limited response rate of 22.2% and 65.3% respectively. Regional/tertiary facilities and district facilities displayed increased awareness and implementation of pharmacovigilance activity than the lower levels of Community Health Centres (CHCs) and Primary Health Centres (PHCs). South Africa”s public healthcare system possesses the infrastructure for a well functioning pharmacovigilance system. However there are gaps in level of functioning at a national, provincial and facility level. Addressing these gaps would show a marked improvement in the system and go a long way towards the contribution of medicine safety information not only locally, but to aid other developing nations.

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Mann, Abbey. "A Medical Perspective on Firearm Safety". Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/6441.

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Denagamage, Thomas Nishantha. "Application of evidence-based medicine to veterinary science and food safety". [Ames, Iowa : Iowa State University], 2008.

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Moss, Brandon Price. "6-Month Effectiveness Safety and Tolerability of Ocrelizumab and Comparative Safety with Rituximab". Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1579784364389245.

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Mullen, Carrie. "Quality Assurance of forensic investigations in toxicology and traffic safety". Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/5465/.

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The work described in this thesis deals with three aspects of quality assurance in the field of forensic toxicology: proficiency testing schemes, validation of analytical methods for the piperazine group of abused drugs and validation of the police field impairment test, used at the roadside to test drivers for drug-induced impairment. Proficiency Testing: Long term reviews were performed for two forensic external quality assurance schemes. Rounds 30 (in 2007) to 48 (in 2012) of the UKAS-accredited commercial Quartz Forensic Blood Toxicology Proficiency Testing Scheme (PTS), and a ten year period from 1999 to 2009 of the freely-available United Nations Office on Drugs and Crime (UNODC) International Collaborative Exercises (ICE). Only limited ICE data could be made available as much of the original data had been stored on a database which had become obsolete, hence the data were only available as the original results forms provided to UNODC by the ICE participants. Data was entered to Microsoft Excel® spreadsheets and Microsoft Access® databases from the original forms for the years 1999, 2001 (2 rounds), 2003 (2 rounds) and 2005 (2 rounds), and summary data was extracted from the UNODC round reports for the years 2007, 2008 and 2009. Four methods of scoring quantitative performance were reviewed and the most suitable, a z-score using an assigned ‘true’ value and a percentage of the true value as acceptable deviation, was applied to reanalyse the participants’ results and assess their performance. Methods of scoring proficiency which relied upon participants’ data to determine acceptable variation were found merely to describe the data rather than challenge participants on whether or not they were performing fit-for-purpose analyses. Factors such as participation, analytes tested, participants’ methods of analysis and participants performance were summarised for each scheme before the performance of the two schemes, and that of their participants, were compared. ICE tested more analytes per annum but from a smaller test menu than Quartz. This resulted in more repetitive testing and allowed for some trend analysis and performance monitoring. It was not possible to observe performance trends with Quartz due to the wide variety of analytes tested. The smaller array of potential analytes and more repetitive nature of ICE testing also meant that performance monitoring and detection of bias were easier to perform, and ICE was shown to be more effective as external quality assurance (EQA). Quartz provided a good educational resource as it incorporated the wide range of drugs which a forensic toxicology laboratory could realistically encounter. Following the review, however, it was recommended for QUARTZ that, to provide a safeguard against bias, more repetitive testing was required and this has now been adopted. Piperazines: All piperazine analogues are now illegal in the UK, registered as Class C of the Misuse of Drugs Act (1971) and schedule 2, part III of the Misuse of Drugs Regulations (2001). Piperazines can elicit similar effects to some ATS and methods for their detection should be available in forensic toxicology laboratories. In the present study, methods were developed for the detection of a range of piperazines in blood using LC-MS/MS (p-MeOPP, p-FPP, BZP, o-MeOPP, p-MPP and TFMPP) and GC-MS (p-FPP, BZP, TFMPP, p-MPP, o-MeOPP, m-CPP, p-MeOPP and p-CPP). Quality assurance required both methods to be validated. For all piperazine analytes accuracy was within ±15% (20% at low concentrations) and precision was within 15% (20% at low concentrations). For both methods LLOD of all analytes was 5 ng/ml of blood and upper limit of quantification was 2 µg/ml of blood. For the GC-MS method lower limits of quantification (LLOQs) were in the range 20 to 30 ng/ml of blood. For LC-MS/MS, LLOQs ranged from 50 to 60 ng/ml of blood, although quantification by the LC-MS/MS method was restricted by the lack of availability of appropriate internal standards. There were no apparent significant matrix effects and recovery by both methods was >60 % and, therefore, acceptable. Short term stability of the piperazine analytes was investigated. Piperazines remain sufficiently stable when stored in the fridge for at least one week, and are stable through three freeze-thaw cycles. There was no detectable degradation when blood samples were left on the bench-top or when extracted ‘in-process’ samples were left in the autosampler for up to 72 hours. The LC-MS/MS method could provide a readily applicable screening method. A small aliquot of a basic drug extract could be screened by LC-MS/MS for the presence of piperazines, leaving the majority of the extract for other analyses, for example, piperazines confirmation or amphetamines analysis. The GC-MS method was suitably validated to provide quantification but application to casework samples remains to be evaluated. It is recommended that piperazine testing be performed for all suspected MDMA or ‘club drug’ intoxication cases. The Field Impairment Test: The detection of drugged drivers primarily depends on the current method which is the driver field impairment test (FIT). FIT comprises measurement of pupil diameter and four physical tasks (the Romberg balance test, walk and turn test, one legged stand and finger to nose test) intended to simultaneously test comprehension, short term memory, balance and motor function. Despite FIT having ISO accreditation, it has been recognised that police officers lack confidence with the protocol and do not apply the test as often as is necessary. The main difficulty arises from the requirement to make a subjective judgement of impairment and officers lack confidence in their ability to do so. FIT has never been fully validated. The present study was designed to meet the urgent requirement to develop FIT into an objective measurement, by determining what constitutes “normal” performance in FIT by unimpaired adults of different ages. FIT performance was recorded for 79 individuals, a statistically determined cohort size, confirmed by breath and oral fluid analysis not to be under the influence of impairing substances. Each error made during FIT, as defined by the FIT standard operating procedure, was recorded and collated in a Microsoft Excel® spreadsheet for analysis. It was found that the definition of ‘errors’ was too stringent as many which are required to be recorded are normal physiological or behavioural characteristics, such as body sway, and most subjects would be unable to complete the task without displaying them. A less stringent, evidence-based definition of “error” was developed which allowed statistically more significant analysis to be performed on the FIT results. A statistically significant difference (P=0.00578) was shown to exist between the FIT performance of individuals under the age of forty years and those aged forty and over. Based on the principles of a PTS, robust mean and standard deviation were used to determine what constituted acceptable performance. Those in the younger age group could be considered impaired if the police officer witnessed more than seven errors, or, in the older age group, more than fifteen errors. Using these criteria the frequency of false positives, i.e. unimpaired drivers being assessed as impaired is estimated to be (less than 3%). Also, the ranges of errors observed in both groups was large and overlapped, such that it may be possible for an impaired person to appear unimpaired. This requires further investigation.

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Al, Dhabbari Fatma. "Nurses' perceptions of patient safety culture in Oman". Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/30724/.

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Al, Salem Gheed F. "An assessment of safety climate in Kuwaiti public hospitals". Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/30685/.

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Background: Patient safety in healthcare organisations received global attention following the Institute of Medicine’s release of its hallmark report “To Err Is Human: Building a Safer Health System”, where it was estimated that 44,000–98,000 patients die annually in US hospitals as a result of errors in care. Similar rates of error and avoidable harm have been reported in different research studies in many modern health systems across the world. “Safety Culture” has been identified as a key element of healthcare organisations’ ability to learn from errors and reduce preventable harm to patients resulting from health care. The perceived importance of safety culture in improving patient safety and its impact on patient outcomes has led to a growing interest in the assessment of safety culture in healthcare organisations. The use of safety climate questionnaires is one of the most popular methods for assessing safety culture. These questionnaires are thought to help in measuring healthcare workers' perceptions of the prevailing safety culture or “safety climate” in their organisations. Since no surveys of safety climate have been conducted at public hospitals in the state of Kuwait, nor are valid or reliable survey instruments available, this thesis aimed to investigate patient safety climate in public hospitals in Kuwait. The main objectives of the study were: 1. To identify an existing safety climate tools to be employed in my PhD thesis. 2. To test the psychometric properties of the identified tool in a sample of Kuwaiti public hospitals. 3. To provide a measure of the prevailing safety climate in Kuwaiti public hospitals. 4. To explore with key stakeholders the main findings of the safety climate survey and identify the potential barriers and facilitators to safety improvement initiatives in Kuwaiti public hospitals. Based on the overall findings, a series of recommendations are made for clinical leaders, policy makers and others to consider and a conceptual model informing a systems’ based approach to safety culture theory and practice is proposed for future research. Methods: A multi-method, triangulated approach including both quantitative and qualitative methods was adopted for the study. There were four phases of the research: A systematic review of published literature on safety climate tools used in acute hospital settings was carried out using seven electronic databases, with manual searches of bibliographies of included papers and key journals. A suitable tool was identified. A cross-sectional survey of 1,511 healthcare staff in three public hospitals was conducted for two purposes: Firstly, to assess the psychometric properties of the identified tool and develop an optimum model for assessing safety climate in Kuwaiti hospitals. Secondly, to provide an assessment of the current state of safety climate in Kuwaiti hospitals. Finally, interviews with key personnel were conducted to extend the examination of the survey findings and provide a rounded picture of the current state of safety climate in Kuwaiti public hospitals. Results: The search strategy identified 3,576 potential papers. Of these, eighty-eight papers were reviewed, with five studies meeting the inclusion criteria. Three out of five studies, covering three tools, were rated as ‘good’ quality papers and reported more robust psychometric properties. The Hospital Survey on Patient Safety Culture (HSOPSC) was selected as the most appropriate for my PhD thesis (in terms of usability, applicability and psychometric properties), and was pilot tested with minor modifications. A modified version of the HSOPSC was used to conduct the survey using a sample of healthcare staff with an 87% (n=1,310) response rate. Results of psychometric evaluation, including exploratory factor analysis, confirmatory factor analysis, reliability and correlation analysis, showed an optimal model of eight factors and 22 safety climate items. General evaluation of the prevailing safety climate amongst the workforce in acute hospital settings was conducted. The dimensions “Teamwork within units” (84%), “organisational learning-continuous improvement” (82%), “supervisor/manager expectations and actions promoting safety” (77%) and “management support for patient safety” (74%) were identified as strongly positive areas for the three hospitals. The dimensions “Non-punitive response to error” (34%), “communication openness” (47%) and “frequency of event reporting” (50%) were identified as areas in need of improvement. Building on the survey findings, interviews with key stakeholders added rich insight into hospital employees' perceptions on safety and allowed exploration of emerging issues in more detail. The research findings of my PhD thesis, and of the literature informed the design of a preliminary framework that aims to extend the examination of the construct of safety climate beyond the domains and items that typically inform safety climate theory to include system wide factors which potentially influence the prevailing safety culture/climate. Conclusions: This is the first validation study of a Standardised safety climate measure in a Kuwaiti healthcare setting. The study assessed the psychometric properties of the HSOPSC questionnaire and constructed an optimal model for assessing patient safety climate in Kuwaiti hospitals. It highlighted important patient safety and staff wellbeing concerns to inform organisational and national learning, and provided a baseline for measuring patient safety climate in Kuwaiti hospitals. As such, my PhD thesis raises and emphasizes the critical importance of appropriate validation of safety climate questionnaires before extending their usage in different countries or healthcare contexts. It provided new knowledge about areas of strength and weakness in safety climate with the potential to drive local improvements in Kuwaiti public hospitals. It is recommended that future investigations of patient safety culture and climate combine both quantitative and qualitative approaches and adopt a system wide approach to inform safety climate theory and questionnaire development, leading to stronger frameworks guiding safety culture research and practice.

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Carson-Stevens, Andrew. "Generating learning from patient safety incident reports from general practice". Thesis, Cardiff University, 2017. http://orca.cf.ac.uk/104070/.

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Internationally, there is an emerging interest in the inadvertent harm caused to patients by the provision of healthcare services. Since the publication of the Institute of Medicine’s report, To Err is Human, in 1999, research and policy directives have predominantly focused on patient safety in hospital settings. More recently, the World Health Organization has highlighted 2-3% of primary care encounters result in a patient safety incident. Given around 330 million general practice consultations occur in the UK each year, unsafe primary care is a poorly understood, major threat to public health. In 2003, a major investment was made in the National Reporting and Learning System to better understand patient safety incidents occurring in England and Wales. Over 40,000 incident reports have arisen from general practice. These have never been systematically analysed, and a key challenge to exploiting these data has been to generate learning from the largely unstructured, free-text descriptions of incidents. My thesis describes the empirical development and application of methods to classify (structure) incident report data. This includes the development of coding frameworks specific to primary care, aligned to the WHO International Classification for Patient Safety, to describe the incident, contributory factors and incident outcomes. I have developed a mixed-methods approach which combines a structured process for coding reports and an exploratory data analysis with subsequent thematic analysis. Analyses of reports can generate hypotheses about priorities for systems improvement in primary care at a local and national level. Existing interventions or initiatives to minimise or mitigate patient safety risks can be identified through scoping reviews. Future research and quality improvement activities should deepen understanding about the risks to patients, and generate knowledge about how interventions made in practice can improve safety.

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Elmi, Ahmed. "Safety of medicines with respect to drug counterfeiting in developing countries". Thesis, Cardiff University, 2013. http://orca.cf.ac.uk/52338/.

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Background: This thesis presents a study of the safety of medicines with respect to drug counterfeiting in developing countries (East Africa and the Middle East). Counterfeit medicines are also present in industrialised countries, but not on the same scale as in developing countries. The aim of the study was to establish the responsiveness of health care professionals at the practice level concerning the counterfeiting of medicinal products in developing countries focusing on six countries in the East African region and seven countries located in the Middle East. Method: The method of data acquisition used was by survey questionnaires issued in 13 developing countries (6 in East Africa and 7 in the Middle East). The questionnaires were delivered to the respondents either personally or by e-mail and the questionnaire, responses were returned by the same means. Respondents returned their questionnaire forms direct to the author either on the same day or later by e-mail. The data were analysed with regard to the specific questions. Results: The study findings suggested that the poorer the country, the higher the degree of counterfeiting. All the respondents (n: 2180) agreed that there was a fake or counterfeit medicine problem in their own country (71% of respondents in Africa and 63% of respondents in the Middle East considered this a major problem). Both branded and generic drugs were counterfeited and the extent of the problem and several other factors concerning counterfeited drugs differed significantly between industrialised and developing countries. The difference depended on drug regulation control and enforcement and also on the quality and the prices in the legal supply chain. In most industrialised countries like the USA, Japan or the members of the EU, the level v of drug counterfeiting is <1% of the total medicines market value. An exception is the former Soviet Union where up to 20% of the market is occupied by counterfeit drugs. In contrast, within regions of Africa, Asia and parts of Latin America, between 10-30% of the available medicines are fakes (WHO 2006) Conclusions: The study showed that healthcare workers were aware of the prevalence of counterfeit medicines and quite a number of them had encountered them in their supply role. There is an indication that the respondents tried to assure themselves of the quality of the drugs they purchased by using several methods. However, no rigorous effort was taken to confirm as well as report suspected counterfeit drugs to regulatory authorities. In the industrialised world, medicines regulatory authorities have developed strict standards and controls to ensure the safety and effectiveness of drugs. However, as this study has found, in less developed countries a lack of human and financial resources within the health sector as a whole restricted the activity of regulatory agencies, resulting in a sub-optimally regulated environment in which substandard drug production persisted without detection.

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Mais fontes

Livros sobre o assunto "Medicine safety"

Silvestro, Giustina De. Transfusion medicine and patient safety. Berlin: De Gruyter, 2013.

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Das, Malay K., e Yashwant V. Pathak, eds. Nano Medicine and Nano Safety. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-6255-6.

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Saha, Gopal B. Radiation Safety in Nuclear Medicine. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-16406-5.

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Maciocia, Giovanni. Safety of Chinese herbal medicine. 2^a ed. Chesham Bois: Su Wen, 2000.

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Pat, Croskerry, ed. Patient safety in emergency medicine. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2009.

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Maciocia, Giovanni. Safety of Chinese herbal medicine. Chesham Bois: Su Wen, 1999.

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Saha, Gopal B. Radiation Safety in Nuclear Medicine. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-24609-8.

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Schmall, Vicki L. Using medicine safely. [Corvallis, Or.]: Oregon State University Extension Service, 1992.

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Schmall, Vicki. Using medicine safely. [Corvallis, Or.]: Oregon State University Extension Service, 1992.

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United States. Food and Drug Administration, ed. Use medicine safely. Rockville, MD (5600 Fishers Lane, HFI-40, Rockville 20857): U.S. Food and Drug Administration, Public Health Service, Dept. of Health and Human Services, 1999.

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Capítulos de livros sobre o assunto "Medicine safety"

Candido, Kenneth D., e Tennison Malcolm. "Fluoroscopic Safety". In Regenerative Medicine, 135–39. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-75517-1_14.

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Absten, Gregory T., e Stephen N. Joffe. "Laser Safety". In Lasers in Medicine, 54–62. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4899-3154-2_6.

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Absten, Gregory T., e Stephen N. Joffe. "Laser safety". In Lasers in Medicine, 47–54. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4899-3156-6_6.

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Ramer, Karen, e Abass Alavi. "Radiation Safety". In Nuclear Medicine Technology, 18–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-09010-7_3.

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Mantel, Eleanor, Janet S. Reddin, Gang Cheng e Abass Alavi. "Radiation Safety". In Nuclear Medicine Technology, 17–25. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-26720-8_3.

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Loke, Dana E., e Garth Walker. "Patient Safety in Emergency Medicine". In Patient Safety, 339–50. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-35933-0_23.

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Baird, Richard A., e Roderic I. Pettigrew. "Medicine and Health Safety". In Series in Biomedical Engineering, 368–71. New York, NY: Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-76495-5_44.

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Barat, Ken. "Laser Safety in Medicine". In Medical Applications of Lasers, 327–61. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0929-5_11.

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Braun, Lesley. "Complementary Medicine and Safety". In Complementary Therapies and the Management of Diabetes and Vascular Disease, 36–48. Chichester, UK: John Wiley & Sons, Ltd, 2006. http://dx.doi.org/10.1002/9780470057438.ch3.

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Killianova, Tereza. "Food Safety". In Encyclopedia of Behavioral Medicine, 890–91. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39903-0_109.

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Trabalhos de conferências sobre o assunto "Medicine safety"

Lu, Chih-Wei. "Medicine Slips Prevention for Patient Safety". In Applied Human Factors and Ergonomics Conference. AHFE International, 2018. http://dx.doi.org/10.54941/10041.

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The medicine deliver effect patient safety and prescription processes are always very important in the hospital. In Taiwan, the numbers of medicine event were 5960 (in 2008) and 9148 (in 2006). The trend of medicine events is increased, so medicine slips prevention is seriously. In this study, we analysis of factors medicine slips then by improving the environment of operating interface to prevent medicine events. Currently, the hospital into the computerized operations situation, deliver medicine correctly is an important part of patient safety, so human-computer interface design such as the computerized physician order entry (CPOE) system, with pop-ups, colors warning to remind staff s of hospitals to avoid the use of to allergy medications and repeated medicine, the errors of medicine name input, as well as the error of using wrong dose to reduce events of human error and decrease the medication slips and promote patient safety.

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Kores Plesničar, Blanka. "Psychiatric Patient, His Safety and Safety of Health Professionals". In 26th Conference Medicine, Law & Society. University of Maribor Press, 2017. http://dx.doi.org/10.18690/978-961-286-021-9.10.

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Možina, Martin, Martin Možina jr. e Miran Brvar. "Medicines Safety and Responsability for MedicinesInduced Injury". In 26th Conference Medicine, Law & Society. University of Maribor Press, 2017. http://dx.doi.org/10.18690/978-961-286-021-9.12.

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MacKay, J. Morag, e Emily Samuel. "SM 05-1568 Safe medicine storage: a look at the disconnect between parent knowledge and behavior". In Safety 2018 abstracts. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/injuryprevention-2018-safety.744.

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Eglite, M. E., J. G. Cirule, M. S. Burcena e J. O. Cernova. "Main occupational medicine problems in Latvia". In III International Scientific Forum "Health And Safety At The Workplace". Polikraft, 2019. http://dx.doi.org/10.31089/978-985-7153-76-3-2019-1-3-94-97.

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Br\^inzei, Nicolae, Irbulat T. Utepbergenov e Vsevolod I. Fettsov. "Improving Reliability of Radiopharmaceuticals Synthesis System Used in Nuclear Medicine". In 33rd European Safety and Reliability Conference. Singapore: Research Publishing Services, 2023. http://dx.doi.org/10.3850/978-981-18-8071-1_p596-cd.

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Nicosia, Vincenzo, Frano Mika, Sabatino De Sanctis, Alessandro Lesma e Massimo Consentino. "Utilising e - Medicine In Remote Locations". In SPE Asia Pacific Health, Safety, and Security Environment Conference and Exhibition. Society of Petroleum Engineers, 2007. http://dx.doi.org/10.2118/108553-ms.

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Norman, J. N., e J. A. Brebner. "A System of Remote Medicine". In SPE Health, Safety and Environment in Oil and Gas Exploration and Production Conference. Society of Petroleum Engineers, 1994. http://dx.doi.org/10.2118/27200-ms.

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Sanglun, Rujeewan Yomsreeken. "PW 2001 Evaluation of potential emergency volunteer community group volunteers. In the care of patients with acute myocardial infarction. (AMI) sam sung district khonkaen. Study of emergency medicine, sam sung hospital. And received fund from national institute for emergency medicine". In Safety 2018 abstracts. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/injuryprevention-2018-safety.698.

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Bartels, Kenneth E., e Thomas R. Fry. "Safe use of lasers in veterinary medicine". In ILSC® 2007: Proceedings of the International Laser Safety Conference. Laser Institute of America, 2007. http://dx.doi.org/10.2351/1.5056635.

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Relatórios de organizações sobre o assunto "Medicine safety"

Zheng, You-you, Ning Liang, Long-kun Liu, Wei-jia Sun, Xue-hui Wang, Yu-xin Sun, Yun-ru Chen, Xiao-xia Han, Zhao-lan Liu e Jian-ping Liu. Effectiveness and Safety of Chinese Patent Medicine for Functional Constipation: A Systematic Review and Network-Meta Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, maio de 2022. http://dx.doi.org/10.37766/inplasy2022.5.0049.

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Review question / Objective: To evaluate the effectiveness and safety of Chinese patent medicine in treatment of functional constipation by using the Network Meta-Analysis. 1. Types of participants: participants diagnosed as functional constipation according to Rome III, Rome IV or other published criteria or guidelines. No limitation on types of FC, age, sex, and nation. Children and pregnant women were excluded. Participants who had other constipation-related diseases including irritable bowel syndrome, functional defecation disorders and opioid-induced constipation were excluded. 2 Types of Interventions. Chinese patent medicine which have been registered with the approval batch number beginning with “Z,” approved by Chinese National Medical Product Administration (NMPA), used alone or in combination with Polyethylene Glycol, Lactulose, Bisacodyl, Prucalopride Succinate, probiotic, or Mosapride which recommended by latest clinical guidelines released by authorized organizations. The dosage, formulation, and route of administration of Chinese patent medicine were not limited. 3 Types of control. Registered Chinese patent medicines used alone, Polyethylene Glycol, Lactulose, Bisacodyl, Prucalopride Succinate, probiotic, Mosapride which recommended by latest clinical guidelines released by authorized organizations or placebo were eligible. 4 Types of outcomes. Primary outcomes were the clinical effect, score of dyschezia and defecation time. Secondary outcomes were adverse events and recurrence rate. 5 Types of study design. Parallel randomized controlled trials (RCTs) were included. Conference abstracts were excluded if full articles were not available.

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Kin, Eunjin, Jungyoon Choi e Sang Yeon Min. Efficacy and safety of herbal medicines external application with Tuina in congenital muscular torticollis : A systematic review and meta-analysis protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, janeiro de 2022. http://dx.doi.org/10.37766/inplasy2022.1.0017.

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Review question / Objective: By 3 to 4 months of age, infants can keep their necks upright and look into both eyes horizontally. But infants with CMT have a wry neck also known as a twisted neck. Complementary therapies have been commonly used to treat CMT, such as tuina, acupuncture, herbal medicine. Among them, external application of herbal medicine is non-surgical and non-invasive inventions so it can be used widely in East Asia. This review aims to evaluate any form of external application of herbal medicines in CMT, such as cream, oil, extract, form of patch, etc. Information sources: We will electronically search the following database 4 English databases(MEDLINE, PubMed, EMBASE, the Cochrane Central Register of Controlled Trials), 3 Chinese databases(China National Knowledge Infrastructure(CNKI), Chinese Scientific Journal Database(VIP), Wan Fang Database), 4 Korean medical databases(Oriental Medicine Advanced Searching Integrated System(OASIS), Korean Studies Information Service System(KISS), National Digital Science Links(NDSL), Research Information Sharing Service(RISS)) from their founding date to June 2022, without any language restrictions.

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Tan, Aihua, Yan Hu, Han Yan, Zheng Zhang, Ziyu Song e Simiao Ran. Efficacy and safety of Chinese Herbal Medicine for Vascular dementia: A protocol of systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, janeiro de 2022. http://dx.doi.org/10.37766/inplasy2022.1.0098.

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Review question / Objective: As a common type of clinical dementia, the prevalence rate of vascular dementia(VaD) increased rapidly in recent years, damaging both patients’ health and social-economic prospect. There is currently no effective treatment for VaD, though western medicines can slightly improve patients' cognitive function, but not brought a significant improvement in daily life ability. Chinese herbal medicine(CHM) has been widely employed to treat dementia for more than 2000 years in China. Despite the proliferation of relevant literature, there is still a lack of evidence to prove the effectiveness and safety of such therapy. Therefore, this systematic review and meta-analysis protocol is aimed to assess the efficacy and safety of CHM forVaD. Information sources: 6 English databases (PubMed, Web of Science, Embase, Springer, CENTRAL and WHO International Clinical Trials Registry Platform) and 4 Chinese databases (Wan fang Database, Chinese Scientific Journals Database, China National Knowledge Infrastructure Database and Chinese Biomedical Literature Database).

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Du, Yuqing, Huimin Lu, Yaoqing Sun, Weian Yuan, Renyan Huang, Xuhong Wang, Guobin Liu e Weijing Fan. Systematic review and meta-analysis of the efficacy and safety of Panax notoginseng saponins in the prevention of lower-extremity deep venous thrombosis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, março de 2023. http://dx.doi.org/10.37766/inplasy2023.3.0032.

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Review question / Objective: P: Participants must be individuals diagnosed with LEDVT. I: Panax Notoginseng Saponions (PNS) alone or PNS combined with routine western medicine treatment; C: Western medicine. O: The Incidence of LEDVT. Condition being studied: The lower-extremity deep vein thrombosis (LEDVT) is a condition that is common in postoperative and intensive care patients. It is caused by impaired venous reflux, endothelial dysfunction and ahypercoagulability. Eligibility criteria: All randomized controlled trials (RCTs) exploring the clinical outcomes of PNS alone or PNS combined with western medicine versus western medicine with LEDVTwere includedAll randomized controlled trials (RCTs) exploring the clinical outcomes of Zishen Yutai Pill plus western medicine versus western medicine with TM in woman were included.

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Zheng, Ruo-xiang, Jia-wei Xu, Bi-yao Jiang, Wei Tang, Chun-li Lu, Xiao-yang Hu e Jian-ping Liu. Mind-body therapies in traditional Chinese medicine for neuropathic pain: a systematic review of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, abril de 2022. http://dx.doi.org/10.37766/inplasy2022.4.0016.

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Review question / Objective: The purpose of this review is to comprehensively evaluate the effectiveness and safety on mind-body therapies of traditional Chinese medicine for neuropathic pain. Condition being studied: According to the definition by the International Association for the Study of Pain (IASP), neuropathic pain is a kind of pain caused by lesions or diseases affecting the somatosensory nervous system. It has brought considerable negative impacts on patients and society. Neuropathic pain is a prevalent disease and can be induced by a variety of clinical conditions such as spinal cord injury (prevalence rate: 53%), induced peripheral neuropathic pain (prevalence rate: 38%), diabetic peripheral neuropathic pain (prevalence rate: 10%-26%), chemotherapy postherpetic neuralgia (3.9-42.0/10,000 people per year), prosopalgia (3-5/10,000 people per year), and so on. However, current recommended medicines for neuropathic pain management could cause dependence and adverse events. Thus, alternatives would be helpful for both patients and clinicians. Mind-body therapy in traditional Chinese medicine (TCM) has a long history in clinical practice for relieving pain and their effectiveness has not been systematically reviewed.The purpose of this review is to comprehensively evaluate the effectiveness and safety on mind-body therapies of traditional Chinese medicine for neuropathic pain.

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Lai, Qiang, Tao Cheng, Wentao Yang, Tianyong Han e Shuyun Xu. Effectiveness and safety of traditional Chinese medicine enema for treating severe acute pancreatitis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, maio de 2022. http://dx.doi.org/10.37766/inplasy2022.5.0163.

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Cheng, Bingjie, Pei Chen e Yihui Deng. Efficacy and safety of integrated traditional Chinese medicine and standard western medicine on patients with acute coronary syndrome: A systematic review protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, abril de 2021. http://dx.doi.org/10.37766/inplasy2021.4.0145.

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Li, Lu, Hongliang Xie, Ling Wang, Aolin Zhang, Xuan Mou, Yifan Lin, Hongli Ma et al. The Efficacy and Safety of Combined Chinese Herbal Medicine and Western Medicine Therapy for COVID-19: A Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, janeiro de 2022. http://dx.doi.org/10.37766/inplasy2022.1.0072.

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Tang, Li-li, Yue-dong Liu, Hong-wu Tao, Wen-zhe Feng, Yu-ping Shu e Fan-yan Meng. The efficacy and safety of ulcerative colitis treatment based on the theory of the " lung–gut axis ": a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, março de 2023. http://dx.doi.org/10.37766/inplasy2023.3.0014.

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Review question / Objective: The purpose of this study was to investigate the difference between the curative effect of traditional Chinese medicine or integrated traditional Chinese and Western medicine on ulcerative colitis under the guidance of lung-intestine axis theory and that of Western medicine alone. The selected research method was to search relevant randomized controlled trial in Chinese and English medical databases. The Cochrane bias risk assessment tool was used to analyze the quality of RCT studies, and RevMan 5.3 was used for efficacy evaluation and meta-analysis. Condition being studied: Ulcerative colitis (UC) is a nonspecific intestinal inflammatory disease that often involves the rectum and colon submucosa. It is characterized by abdominal pain, diarrhea and purulent bloody stool. There is no specific therapy for ulcerative colitis at present. This study investigates the curative effect of traditional Chinese medicine or integrated traditional Chinese and Western medicine therapy on UC under the guidance of lung-intestine axis theory and provides a theoretical basis for the clinical treatment of UC.

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Liu, Yu, Mingquan Li, Liangbin Zhao, Naijing Ye e Lai Kuan Teh. Efficacy and safety of traditional Chinese medicine enema in the treatment of diabetic nephropathy. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, abril de 2021. http://dx.doi.org/10.37766/inplasy2021.4.0072.

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