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1

Tsvetkova, V. S., T. N. Budkina, M. O. Prokhorenkova, A. V. Vinokurova, M. M. Lokhmatov, A. S. Potapov, E. L. Semikina, A. N. Surkov e A. P. Fisenko. "Accuracy of endoscopic indices in assessing the activity of ulcerative colitis in children". Voprosy praktičeskoj pediatrii 17, n.º 1 (2022): 36–42. http://dx.doi.org/10.20953/1817-7646-2022-1-36-42.

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Objective. To evaluate the accuracy and informativeness of two endoscopic indices for ulcerative colitis (UC) activity recommended for pediatric practice (Ulcerative Colitis Endoscopic Index of Severity (UCEIS) and Mayo ES) and analyze their correlation with clinical and laboratory indicators of disease activity. Patients and methods. This study included 80 patients (42 boys, 38 girls) aged 5 to 18 years diagnosed with UC. The activity of UC was evaluated using the Pediatric Ulcerative Colitis Activity Index (PUCAI). Laboratory examination included measurement of hemoglobin, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and fecal calprotectin. All children underwent ileocolonoscopy with the assessment of endoscopic severity using the UCEIS and Mayo ES. Results. We identified a significant correlation between UCEIS and Mayo ES (Spearman ρ 0.771, p < 0.001). Both endoscopic indices also correlated with PUCAI (Spearman ρ 0.660, p < 0.001 and Spearman ρ 0.625, p < 0.001, respectively). The level of fecal calprotectin demonstrated the highest correlation with UCEIS and Mayo ES (Spearman ρ 0.594 and 0.595, p < 0.001, respectively). Conclusion. The UCEIS and Mayo ES are highly accurate and informative for the assessment of UC inflammatory activity in children. The UCEIS scale is more detailed, while Mayo ES scale is easier to use in clinical practice. Key words: ulcerative colitis, colonoscopy, endoscopic activity indices, UCEIS, Mayo ES.
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Huynh Dr, H., H. Ma, D. Isaac, K. Novak, P. Almeida, J. Kim, A. Kuc, M. Carroll e E. Wine. "P177 Validation of UC Intestinal Ultrasound (UC-IUS) Index for children with Ulcerative Colitis". Journal of Crohn's and Colitis 16, Supplement_1 (1 de janeiro de 2022): i245. http://dx.doi.org/10.1093/ecco-jcc/jjab232.305.

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Abstract Background Transabdominal bowel ultrasound (TABUS) is an ideal tool to assess transmural inflammation in children with Ulcerative Colitis (UC). The UC intestinal US (UC-IUS) Index was developed and validated using endoscopy with strong correlation between UC-IUS Index and Mayo subscore (ρ 0.830; p&lt;0.001). Our aim was to determine how bowel wall thickness (BWT) and UC-IUS Index performed in children at diagnosis in comparison to endoscopy using the Mayo score. Methods Subjects (0–18 years old) with suspected inflammatory bowel disease (IBD) were prospectively enrolled. Baseline TABUS (excluding rectum due to poorly seen) done prior to endoscopy. Pediatric Ulcerative Colitis disease Activity Index (PUCAI) and Mayo were calculated, albumin, C-reactive protein (CRP) and fecal calprotectin (FCP) collected. The UC-IUS Index was calculated for each segment – sigmoid (SC), descending (DC), transverse (TC) and ascending (AC) [bowel wall thickness (BWT) (mm): &gt; 2 =1, &gt;3 =2 and &gt;4 =3; doppler: spots=1 and stretches =2, abnormal haustrations = 1 and fat wrapping =1]. Spearman’s rank (rho) and Pearson’s correlation (r) assess for a correlation. Receiver operating characteristic [ROC] analysis performed for BWT to determine sensitivity and specificity of BWT cut-offs in the UC-IUS. Results Of the 75 subjects recruited for suspected IBD, 26 had UC with mean age 15 years (SD 3.33) and 5 had normal US. Twenty three have extensive pancolitis. Mean PUCAI score: 60 (SD 23.28), CRP 22.62 (SD 39.5) mg/l, albumin 35.6 (SD 6.96) g/l and fecal calprotectin of 2223 (SD 1757) mg/kg. ROC curves generated using a total of 122 colonic segments. BWT of 2 mm discriminates between active and inactive:Mayo 0 and Mayo1-3 [sensitivity 84.9%; specificity 86.2%; an area under the curve [AUC] 0.900]; a cut-off of 3mm discriminates between Mayo 1 from Mayo 2–3 [sensitivity of 61.3%; specificity 90.5%; AUC 0.858]; a cut of 4mm discriminates Mayo 3 (sensitivity 64.7%; specificity 85.7 %; AUC 0.876). BWT and UC-IUS scores of all colonic segments correlated highly positively with the Mayo score of corresponding segments (rho=0.684, r=0.660, p&lt;0.001) and (rho=0.750, r=0.722, P&lt;0.001) respectively. The UC-IUS Index correlates poorly with CRP, ESR, and Fecal Calprotectin - r = 0.262, 0.346 and 0.100 respectively; p&gt;0.05. Conclusion BWT and UC-IUS Index correlated highly positively with the Mayo subscore in children with UC. UC-IUS has a better correlation than BWT. BWT cut-off of 2mm discriminate between normal and mild Mayo is optimal. Cut-offs of 3 mm and 4 mm for moderate and severe Mayo may be too high in children with lower sensitivity. A larger cohort of children with UC will need to be studied to determine optimal BWT cut-off for moderate and severe disease.
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Sarbagili-Shabat, Chen, Dror Weiner, Joram Wardi, Lee Abramas, Michal Yaakov e Arie Levine. "MODERATE TO SEVERE ENDOSCOPIC INFLAMMATION IS FREQUENT AFTER ACHIEVING CLINICAL REMISSION IN PEDIATRIC ULCERATIVE COLITIS". Inflammatory Bowel Diseases 27, Supplement_1 (1 de janeiro de 2021): S13. http://dx.doi.org/10.1093/ibd/izaa347.031.

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Abstract Background Pediatric ulcerative colitis (UC) is characterized by low sustained remission rates and frequent extension of disease even if clinical remission is obtained with therapy. Moderate to severe endoscopic activity is a risk factor for relapse while evidence regarding early mucosal healing or persistence of inflammation after remission in children is not available. Our aim was to evaluate if persistence of significant inflammation is common and could explain the high relapse rate in pediatric UC. Methods Pediatric UC patients with clinical remission, defined as pediatric UC activity index (PUCAI) scores &lt; 10, were prospectively assessed for mucosal healing by endoscopy 3–5 months after remission was documented. Mayo score was assessed for each segment by a blinded adult gastroenterologist using central reading. Symptomatic patients prior to sigmoidoscopy were excluded Sustained remission was assessed retrospectively at 18 months follow-up. Results Forty-six children were enrolled, 28 children in continuous clinical remission at time of sigmoidoscopy were included in the final analysis. Mayo 0 was present in 12/28 (42.86%), Mayo 1 in 2/28 (7.1%) and Mayo 2–3 in 14/28 (50.0%) endoscopies. Among 23/28 patients with follow-up through 18 months, remission was sustained in 2/11 (18.18%) of patients with Mayo 2 and 3 versus 6/12 (50.0%) with Mayo score 0–1. Conclusion Over 50% of children assessed for mucosal healing 3–5 months after clinical remission is obtained have residual disease activity, primarily moderate to severe inflammation which was associated with lower sustained remission. Early sigmoidoscopy after clinical remission for assessment of mucosal disease should be considered in pediatric UC.
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Sarbagili Shabat, C., D. Weiner, J. Wardi, L. Abramas, M. Yaakov e A. Levine. "P640 Moderate to severe endoscopic inflammation is frequent after clinical remission in pediatric ulcerative colitis: A cause for disease extension and relapse?" Journal of Crohn's and Colitis 14, Supplement_1 (janeiro de 2020): S530—S531. http://dx.doi.org/10.1093/ecco-jcc/jjz203.768.

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Abstract Background Pediatric ulcerative colitis (UC) is characterised by low sustained remission rates and frequent extension of disease even if clinical remission is obtained. Current therapy in pediatric UC is driven primarily by clinical response. Extension of disease and high relapse rates may be due to a failure to obtain mucosal healing with treatment despite clinical remission. Our aim was to evaluate this possibility by assessing endoscopic disease activity after remission was obtained. Methods Pediatric UC patients with clinical remission, defined as sustained PUCAI &lt; 10 three months after remission was obtained, were prospectively assessed for mucosal healing by endoscopy. Mayo score was assessed for each segment by a blinded adult gastroenterologist using central reading. Results 41 children were enrolled after informed consent, 7 were excluded because of a PUCAI score 10–15 at the time of sigmoidoscopy. Thirty-four Sigmoidoscopies were performed 12–20 weeks after reporting clinical remission. Mucosal healing Mayo 0 was present in 15 endoscopies (44%), Mayo 1 was present in 2 endoscopies (6%) and moderate to severe endoscopic scores Mayo 2–3 was present in 17 endoscopies (50%). Conclusion About 50% of children assessed for mucosal healing 3–5 months after clinical remission is obtained have residual moderate to severe inflammation. Inadequate endoscopic improvement despite clinical remission may explain disease extension and the high relapse rate in children.
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Gajdobranski, Djordje, Dragoljub Zivanovic, Aleksandra Mikov, Andjelka Slavkovic, Dusan Maric, Zoran Marjanovic e Vukadin Milankov. "Scaphoid fractures in children". Srpski arhiv za celokupno lekarstvo 142, n.º 7-8 (2014): 444–49. http://dx.doi.org/10.2298/sarh1408444g.

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Introduction. Scaphoid fractures are rare in childhood. Diagnosis is very difficult to establish because carpal bones are not fully ossified. In suspected cases comparative or delayed radiography is used, as well as computerized tomography, magnetic resonance imaging, ultrasound and bone scintigraphy. Majority of scaphoid fractures are treated conservatively with good results. In case of delayed fracture healing various types of treatment are available. Objective. To determine the mechanism of injury, clinical healing process, types and outcome of treatment of scaphoid fractures in children. Methods. We retrospectively analyzed patients with traumatic closed fracture of the scaphoid bone over a ten-year period (2002-2011). The outcome of the treatment of ?acute? scaphoid fracture was evaluated using the Mayo Wrist Score. Results. There were in total 34 patients, of mean age 13.8 years, with traumatic closed fracture of the scaphoid bone, whose bone growth was not finished yet. Most common injury mechanism was fall on outstretched arm - 76% of patients. During the examined period 31 children with ?acute? fracture underwent conservative treatment, with average immobilization period of 51 days. Six patients were lost to follow-up. In the remaining 25 patients, after completed rehabilitation, functional results determined by the Mayo Wrist Score were excellent. Conclusion. Conservative therapy of ?acute? scaphoid fractures is an acceptable treatment option for pediatric patients with excellent functional results.
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Yogi, Sushil, Dinesh Kumar Shrestha e Aman Shah. "Evaluation of Displaced Medial Epicondyle Fracture in Children Treated Operatively with K Wire". Journal of Nepalgunj Medical College 20, n.º 1 (31 de julho de 2022): 43–46. http://dx.doi.org/10.3126/jngmc.v20i1.48342.

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Introduction: Medial epicondyle fractures of humerus are one of the common pediatric elbow injuries accounting for nearly 11% of the elbow injuries. This avulsion apophyseal fracture can lead to non-union and valgus instability. Thus, open reduction and internal fixation is helpful in maintaining union and a stable functioning elbow joint. Aims: To evaluate the outcome of operative management of displaced medial epicondyle fracture of humerus by open reduction and internal fixation with Kirschner wires using MAYO elbow scoring. Methods: This prospective observational study was conducted at the Department of Orthopedics of Nepalgunj Medical College and Teaching Hospital, Kohalpur from July 2020 to December 2021 in childrenbetween six to 16 years of age. All the patients in study were treated by open reduction and internal fixation with K wires. Mayo elbow performance score was used for evaluating functional outcome. Results: Thirty six patients were included with the mean age of 11.5 years (SD ± 2.5). Twenty five patients were males and 11 were females. Left side was found to be predominantly involved in 23 patients (66.6%). The mean duration of union was found to be 6.6 weeks (SD±0.6). Thirty four patients had excellent result in Mayo elbow performance score while two patients showed good result. The mean Mayo elbow performance score was 96.4 (SD± 3.9). Conclusion: Open reduction and internal fixation with K wires in this type of fracture had excellent to good results. The complications like nonunion and valgus instability are found to have fewer occurrences in children treated with operative means of treatment.
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Hamilton, Kathy. "Book Review: Consumer Kids - How Big Business is Grooming Our Children for Profit". International Journal of Market Research 51, n.º 5 (janeiro de 2009): 1–4. http://dx.doi.org/10.1177/147078530905100501.

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Facer, George W., AnnaMary Peterson, Robert H. Brey, Mitchell Marion, Michael Cevette, Karla Balko, J. Douglas Green, Darrell Rose e Angela Pool. "The Mayo Clinic Experience with the Cochlear Implant". Ear, Nose & Throat Journal 73, n.º 3 (março de 1994): 149–55. http://dx.doi.org/10.1177/014556139407300307.

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The implantati on of a cochlear electronic prosthetic device is an accept able means of improving the communication ability of pre- and postlinguaIIy deafened children and adults. A significant number of patients in this series are in the senior citizen age group. It has been beneficial in improving communication ability in selected profoundly deafened individuals. There has been a significant improvement in the cochlear electronic prosthetic device since the initial report of Djourno1 in 1957.
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Rahmadini, Aprilia Putri. "RATIONAL EMOTIVE THERAPY IBU YANG MEMILIKI ANAK DENGAN THALASSAEMIA BETA MAYO". Jurnal Ilmiah Psyche 12, n.º 1 (10 de janeiro de 2019): 81–90. http://dx.doi.org/10.33557/jpsyche.v12i1.600.

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Beta Thalassaemia Major is a genetic blood disorder that causes blood cells red rapidly destroyed in 20-30 days so that the body is deprived of blood. Treatment can be done during this time is a lifetime of blood transfusions. Their conditions of denial of information mother about the child's condition, as was the condition of self is not a carrier of thalassemia trait, blaming the pair as a nature, thinking irrational that the child's illness is a punishment from God for their sins in the past, the child has no future again, resulting in the emergence of maternal behavior that may endanger the lives of children like too late to bring the child to transfusion. Research Purposes is to produce a group counseling program with Rational Emotive Behavior Therapy (REBT) approach in order to increasing acceptance of mothers of children with beta thalassemia major. Research Design is one group pretest-posttest. Group counseling with REBT approach is done in 6 meetings. In the process, the mother will discuss issues with members of the group and counselors who help mothers to detect the irrational belief that appears, discriminating rational beliefs, and challenging that belief, to be replaced by a rational belief. The subject are mothers who have children with beta thalassemia major amounted to 2 people. Results known to both participants are still in bargaining phase. However, prevalence increased mother’s acceptance of children with beta thalassemia major, marked by decreased aspects of denial and anger on both mother. Conclusion Group counseling with REBT approach can improve mother’s acceptance of children with beta thalassemia major.
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Anderson, Heather N., Joseph A. Dearani, Sameh M. Said, Mark D. Norris, Kavitha N. Pundi, Angela R. Miller, Michael L. Cetta, Benjamin W. Eidem, Patrick W. O'Leary e Frank Cetta. "Cone Reconstruction in Children with Ebstein Anomaly: The Mayo Clinic Experience". Congenital Heart Disease 9, n.º 3 (23 de dezembro de 2013): 266–71. http://dx.doi.org/10.1111/chd.12155.

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Thornton, Sally Webb. "Grief Transformed: The Mothers of the Plaza De Mayo". OMEGA - Journal of Death and Dying 41, n.º 4 (dezembro de 2000): 279–89. http://dx.doi.org/10.2190/yvkv-7601-8vkd-vm5t.

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In Argentina during the years 1976–1983 the military assumed power, employing oppression, torture, death, and disappearance to intimidate the citizenry. A group of mothers, who met while searching for their “disappeared” children, banded together in 1977, organized the group “Madres de la Plaza de Mayo” (Mothers of the Plaza de Mayo), and protested publicly the atrocities that were being inflicted on the Argentine people. Through the support of their group, the public protesting, and the continuation of their disappeared children's work, the Mothers transformed their grief into positive action.
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Schiller, JE. "Reflex sympathetic dystrophy of the foot and ankle in children and adolescents". Journal of the American Podiatric Medical Association 79, n.º 11 (1 de novembro de 1989): 545–51. http://dx.doi.org/10.7547/87507315-79-11-545.

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Over a 12-year period, seven adolescent patients with reflex sympathetic dystrophy were seen in the Mayo Clinic Foot Clinic. The details of these cases are presented, and the literature pertaining to reflex sympathetic dystrophy in children is reviewed.
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Pavone, Vito, Andrea Vescio, Maria Riccioli, Annalisa Culmone, Pierluigi Cosentino, Marco Caponnetto, Sara Dimartino e Gianluca Testa. "Is Supine Position Superior to Prone Position in the Surgical Pinning of Supracondylar Humerus Fracture in Children?" Journal of Functional Morphology and Kinesiology 5, n.º 3 (31 de julho de 2020): 57. http://dx.doi.org/10.3390/jfmk5030057.

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Background: Supracondylar humerus fracture (SCHF) is a frequent injury in pediatric ages. Closed reduction and percutaneous pin fixation is a common treatment of displaced SCHF. Surgery is usually performed in the supine position; otherwise the prone position allows an easier fracture reduction and a safe placement of pins. The aim of study is to compare the clinical and radiographic results of the treatment of displaced SCHF, comparing two different intra-operative positionings. Methods: 59 SCHF affected children were retrospectively divided into supine (Group 1; n = 34) and prone (Group 2; n = 25), according to intraoperative position. All treated subjects were clinically evaluated according to Flynn’s criteria and Mayo Elbow Performance Score, and radiographically, including the measurement of the Baumann angle. Results: Clinically, Group 1, according Flynn’s criteria, had excellent cosmetic outcome in 32 subjects (94.1%). Mean MAYO Score was 96.0 ± 3.8. Group 2, according Flynn’s criteria, had excellent cosmetic outcomes in 23 subjects (92.0%). Mean MAYO Score was 97.8 ± 3.3. Radiographically, mean difference of Baumann’s angle between the injured limb and the normal limb was 5.5° ± 1.0° in Group 1 and 5.1° ± 1.1° in Group 2. Conclusion: Both supine and prone positioning achieved a satisfying outcome with similar results in joint function recovery and complications.
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Romanchishen, Aleksandr Filippovich, e Geoffrey B. Thompson. "Children Thyroid Cancer treatment in Saint-Petersburg Endocrine SurgeryCenter and Mayo Clinic". Endocrine Surgery 7, n.º 4 (17 de fevereiro de 2015): 37. http://dx.doi.org/10.14341/serg2014437-42.

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Sharif, Muhammad, Kashif Bashir, Hafiz Muhammad Arif, Ahmad Hassan, Muhammad Azam e Muhammad Soban Sharif. "Frequency, Pattern and Management of Dog Bite injuries in Children in a Developing Country". Pakistan Journal of Medical and Health Sciences 16, n.º 1 (18 de janeiro de 2022): 101–3. http://dx.doi.org/10.53350/pjmhs22161101.

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Aims: To collect and analyze data regarding frequency, pattern, and management of dog bite injuries in children so that it can be reported to health authorities to launch preventive measures plan against dog bite trauma in children and make sure availability of immunoglobulin and vaccine in proper quantity at proper place to prevent its misuse and expiry. Study design: Observational descriptive study. Setting: Department of Pediatric Surgery King Edward Medical University/ Mayo Hospital Lahore. Duration of study: One year from January 2018 to December 2018. Methods: All patients with dog bite injuries admitted through emergency in department of Pediatric Surgery King Edward Medical University/ Mayo Hospital Lahore were included in the study. Demographic data regarding age, gender, mechanism and severity of dog bite trauma and management recorded on detailed Performa. Results: During one year period a total of 445 patients with dog bite injuries presented in pediatric surgical emergency. Out of these 37.8% patients were admitted and 62.2% patients with minor injury were discharged on same day after proper wound management and vaccination in emergency department. Majority were males and most common age at presentation was from 4-8 years. Conclusion: As dog bite injuries are preventable so there is need to give education to children and families about preventive measures against dog bite injuries and proper treatment like immunoglobulin and vaccination. Keywords: Dog bite trauma, children, Frequency, management
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Shrestha, Pragya, Chung-Il Wi, Hongfang Liu, Katherine S. King, Euijung Ryu, Jung Hyun Kwon, Sunghwan Sohn, Miguel Park e Young Juhn. "Risk of pneumonia in asthmatic children using inhaled corticosteroids: a nested case-control study in a birth cohort". BMJ Open 12, n.º 3 (março de 2022): e051926. http://dx.doi.org/10.1136/bmjopen-2021-051926.

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BackgroundInhaled corticosteroids (ICSs) are important in asthma management, but there are concerns regarding associated risk of pneumonia. While studies in asthmatic adults have shown inconsistent results, this risk in asthmatic children is unclear.ObjectiveOur aim was to determine the association of ICS use with pneumonia risk in asthmatic children.MethodsA nested case-control study was performed in the Mayo Clinic Birth Cohort. Asthmatic children (<18 years) with a physician diagnosis of asthma were identified from electronic medical records of children born at Mayo Clinic from 1997 to 2016 and followed until 31 December 2017. Pneumonia cases defined by Infectious Disease Society of America were 1:1 matched with controls without pneumonia by age, sex and asthma index date. Exposure was defined as ICS prescription at least 90 days prior to pneumonia. Associations of ICS use, type and dose (low, medium and high) with pneumonia risk were analysed using conditional logistic regression.ResultsOf the 2108 asthmatic children eligible for the study (70% mild intermittent and 30% persistent asthma), 312 children developed pneumonia during the study period. ICS use overall was not associated with risk of pneumonia (adjusted OR: 0.94, 95% CI: 0.62 to 1.41). Poorly controlled asthma was significantly associated with the risk of pneumonia (OR: 2.03, 95% CI: 1.35 to 3.05; p<0.001). No ICS type or dose was associated with risk of pneumonia.ConclusionICS use in asthmatic children was not associated with risk of pneumonia but poorly controlled asthma was. Future asthma studies may need to include pneumonia as a potential outcome of asthma management.
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Qurat ul Ain Khalid, Imran Mahmood Khan, Wajeeha Amber, Aqmal Laeeq Chishti e Khawaja Amjad Hassan. "Assessment of Complete Coverage of Expanded Program on Immunization in Children at Mayo Hospital Lahore, Pakistan". Journal of Islamabad Medical & Dental College 9, n.º 1 (26 de março de 2020): 12–16. http://dx.doi.org/10.35787/jimdc.v9i1.501.

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Background: Goal of the expanded program on immunization (EPI) is to ensure full immunization of children under one year of age to globally eradicate poliomyelitis, tetanus, measles-related deaths and to extend all new vaccines and preventive health interventions to children in all parts of the world. Demographic and health survey 2012-13 showed that in Pakistan complete immunization coverage is very low (54%) to achieve this goal. The objective of this study was to assess any improvement in terms of vaccination coverage in Pakistan in the last 3-4 years.Material and Methods: This descriptive cross-sectional study was carried out at outpatient department of Pediatric Medicine of Mayo Hospital Lahore from May, 2016 till November, 2016. The non-probability purposive sampling technique was used to include patients after taking informed consent. Demographic details were collected and parents were questioned about different vaccinations received and confirmed through vaccination card. Data analysis was done through SPSS version 20 and results were presented as frequencies and percentages. Chi-square test was applied for association among categorical variables.Results: Complete coverage of expanded program on immunization was achieved in 86% children. A statistically significant difference was noted between mother’s education and immunization coverage of children (P-value 0.013).Conclusions: Education of mother and socioeconomic status were two significant factors affecting immunization coverage. In order to meet target of 95% immunization coverage rate set by WHO, more awareness should be created among people with low socioeconomic status along with improvement of immunization facilities in these areas.Key words: Children, Expanded Program on Immunization, Immunization Coverage
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., Elmanssury, Ahmed ., Elnadif ., Dafalla ., Safa . e Abdalla . "Prevalence of Diarrhea and Association with Socio-Demographic Factors among Children Under Five in Mayo Camp-Khartoum State Sudan". Pakistan Journal of Medical and Health Sciences 16, n.º 3 (31 de março de 2022): 1100–1103. http://dx.doi.org/10.53350/pjmhs221631100.

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Background: Diarrhoeal diseases remain among the most common causes of mortality and morbidity in children, particularly in low- and middle-income countries (LMICs). In 2013, of the 6.3 million children worldwide who died before they reached their fifth birthday, about half (3.2 million) died from infectious diseases, with diarrhoea killing more than 500,000 children. Sudan has one of highest prevalence rates of diarrhoea and Global Acute Malnutrition. Objectives: To determine the prevalence of diarrhea and impact of socio-demographic factors on the prevalence among Children under five years, Methodology: a community-based cross-sectional research was carried out to study the prevalence of diarrhoea among children under 5 years of age. Results: The average prevalence of diarrheal cases occurring during the 2 weeks preceding the interview was 35.0 percent (n = 311). The prevalence was higher among boys than among girls (25% and 10%, respectively). Our research showed that sociodemographic factors such as family size, number of < 5 siblings and occupation of the mother were not significantly correlated with diarrheal disease in children under 5 years of age, whereas the research showed a high significance between the educational level of the mother and the diarrheal disease family income in children under 5 years of age. Conclusions: our study showed High prevalence of diarrhea in children under the age of five, with the highest prevalence among male compared with female. correlation highly associated between education of mothers, income levels, and diarrheal disease. Keywords: Prevalence, Diarrhea, sociodemographic, children, Association
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Zamdayu, Naomi M., Mohammed A. Qadeer, Godly Chessed e Markus I. Francis. "Prevalence of urinary schistosomiasis among children from three selected local government areas in Adamawa State, Nigeria". Dutse Journal of Pure and Applied Sciences 9, n.º 3a (10 de outubro de 2023): 168–78. http://dx.doi.org/10.4314/dujopas.v9i3a.17.

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Schistosomiasis is a socio-economic and public health important human parasitic disease in the tropics. This study was carried out to determine the prevalence of urinary schistosomiasis among children in Ganye, Jada and Mayo Belwa Local Government Areas (LGAs) of Adamawa State. Urine samples were collected from 600 children between the ages of 5-16, analyzed using modified concentration sedimentation method and examined using microscopy. Diagnosis was based on the presence of Schistosoma haematobium eggs in urine samples. The overall prevalence of urinary schistosomiasis was 5.2% (32/600). Ganye LGA had the highest number positive cases with the prevalence of 9.5% (19/200), followed by Mayo Belwa LGA 4.0% (8/200) and the least in Jada LGA 2.5% (5/200). There was statistically significant difference in the prevalence of schistosomiasis among children and the different LGAs (X2 = 10.761; p<0.05). Highest prevalence of 8.3% was recorded between age groups of 13-16 years, followed by 4.9% in 5-8 years and least of 4.8% in 9-12 years. There was no statistical significant difference between prevalence of schistosomiasis among the age groups (p>0.05). Male children showed higher prevalence (7.5%) than female children (3.1%) with statistical significant difference (p<0.05). Based on parent education, children whose parents had non-formal education had higher prevalence (7.8%) and the least (0.0%) was recorded in children whose parent had tertiary education. Children whose parents were farmers had higher prevalence (5.8%) and the least prevalence was recorded in the children of civil servants (2.7%). No statistical significant association was found between prevalence of schistosomiasis with parent education and occupation (p>0.05). The present study reveals low prevalence of urinary schistosomiasis among children. A further expanded study that may cover the entire state as well as control measures designed to target the parasite and its intermediate host to prevent higher prevalence in future is recommended.
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Sobze Sanou, Martin, Andre Izacar Gael Bita, Ghyslaine Bruna Djeunang Dongho, Benjamin Azike Chunkukundun, Armand Tiotsa Tsapi, Isidore Sieleunou e Germaine Sylvie Nkengfack Nembongwe. "Multidimensional Poverty and Acute Malnutrition of Children in Households of Mayo-danay Division, Cameroon". International Journal of Nutrition and Food Sciences 9, n.º 1 (2020): 25. http://dx.doi.org/10.11648/j.ijnfs.20200901.15.

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Hudson, A., H. Ma, C. Lo, J. Kim, A. Kuc, K. Novak, M. Carroll, E. Wine, D. Isaac e H. Huynh Dr. "P178 Evaluation of the Ulcerative Colitis Intestinal Ultrasound (UC-IUS) Index in Pediatric patients with newly diagnosed ulcerative colitis". Journal of Crohn's and Colitis 17, Supplement_1 (30 de janeiro de 2023): i332—i333. http://dx.doi.org/10.1093/ecco-jcc/jjac190.0308.

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Abstract Background Transabdominal bowel ultrasound (TABUS) is a non-invasive tool that can be used to assess bowel inflammation in ulcerative colitis (UC). It is particularly attractive for use in children, given the need for general anesthesia when undergoing endoscopic assessment of bowel inflammation. A standardized TABUS scoring system in UC has only been developed in adults (the UC Intestinal Ultrasound (UC-IUS) Index). Our aim was to evaluate the UC-IUS Index in Pediatric patients. Methods Pediatric patients (&lt;18 years old) with suspected UC were prospectively enrolled. TABUS was performed for the right side colon, transverse, descending, and sigmoid colons. UC-IUS Index scores were calculated: bowel wall thickness (BWT) (&gt;2mm=1, &gt;3mm=2, &gt;4mm=3), Doppler signal (spots=1, stretches=2), haustrations (abnormal=1), and fat wrapping (present=1). Mayo endoscopic subscore (for each segment), Pediatric Ulcerative Colitis Activity Index (PUCAI), and inflammatory biomarkers were collected. Non-parametric tests were used to correlate UC-IUS and BWT with Mayo endoscopic subscores. Receiver operating characteristic (ROC) analyses evaluated the UC-IUS Index BWT cut-offs. Results Fifty-two patients (56% male) were included (Table 1). Data for 206 colonic segments were analyzed (2 segments missing due to 1 incomplete colonoscopy). Total UC-IUS scores significantly correlated with CRP (rho=0.61), albumin (rho=-0.49), PUCAI (rho=0.54), FCP (rho=0.41). UC-IUS Index scores and mean BWT for each segment showed significant moderate correlations with Mayo sub-scores of that segment (rho=0.60 and rho=0.58, respectively) (p&lt;0.001) (Fig 1). These correlations were strong in the right colon (rho=0.77, rho=0.69), and moderate in the transverse (rho=0.52, rho=0.56), descending (rho=0.43, rho=0.50), and sigmoid (rho=0.50, rho=0.46) colons (p&lt;0.01). The adult UC-IUS 2mm cut-off (Mayo 0 vs. Mayo 1-3) performed similarly in our Pediatric patients (sensitivity 80%, specificity 96%, area under the curve (AUC) 0.92). The 3mm (Mayo 0-1 vs. Mayo 2-3) and 4mm (Mayo 0-2 vs. Mayo 3) cut-offs had lower sensitivity (sensitivity 44%, specificity 98%, AUC 0.87; sensitivity 59%, specificity 92%, AUC 0.80) (Fig 2). Thinner BWT cut-offs performed better: 2.5mm (sensitivity 65%; specificity 89%) and 3.5mm (sensitivity 71%; specificity 86%). Fig 1: Fig 2: Conclusion In Pediatric patients with newly diagnosed UC, TABUS was a useful tool, with the UC-IUS and BWT correlating well with their endoscopic, clinical, and biochemical disease activity. Compared to the adult UC-IUS Index, Pediatric patients need a thinner BWT cut-off to better discriminate between mild vs. moderate/severe disease (2.5mm instead of 3mm) and mild/moderate vs. severe disease (3.5mm instead of 4mm).
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Irianto, Komang Agung, Raymond Parung e William Putera Sukmajaya. "Open reduction in neglected elbow dislocation in children: a case series". Universa Medicina 38, n.º 1 (30 de janeiro de 2019): 63. http://dx.doi.org/10.18051/univmed.2019.v38.63-68.

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Background<br />Elbow deformity in children due to neglected proper fracture management is a devastating condition. The stiffness and pain complicated the function in daily activity. Successful management of neglected elbow dislocation is a challenging problem for orthopedic surgeons. In this study, we aimed to evaluate results of open reduction for neglected elbow dislocation in children.<br /><br />Case Description<br />This is a case series of 13-14 years old neglected elbow dislocations, for up to 15 months. Open reduction after external distractor and followed by intensive rehabilitation was implemented. Clinical and functional outcome were evaluated within 4-7 years. Initial average elbow flexion was 53,3°, extension was 0°, arc of flexion was 53,3°, arc of pronation-supination was 150° and Mayo Elbow Performance Index (MEPI) was 80. Clinical and functional outcome were evaluated within 4-7 years. At follow-up after open reduction, the improvement in whole range of movement was significant. Average elbow flexion was 118,3°, extension was 36,67°, arc of flexion was 81,67°, arc of pronation-supination was 133°. The average improvement of flexion was 65°, arc of flexion was 31,67°, and arc of pronation-supination was 8,3°. The average loss of flexion was 15,5%, arc of flexion was 44,2%, and arc of pronation-supination was 10,7% compared with uninjured side. The average Mayo Elbow Performance Index (MEPI) was 96,67; all with excellent results.<br /><br />Conclusion<br />Planned and well execution open reduction in pediatric neglected elbow dislocation may bring back the painless movement within normal daily function.
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Leyton, Cristian Alvarado. "Apropiación, Not Kinship". Anthropos 116, n.º 1 (2021): 1–16. http://dx.doi.org/10.5771/0257-9774-2021-1-1.

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This article discusses how resignifications of the human rights NGO Abuelas de Plaza de Mayo contributed to transformations of post-dictatorial culture. For decades hegemonic media and perpetrators engaged state terror’s reasoning to confront Abuelas’ call for “restitution” of the children who “disappeared” during the last dictatorship in Argentina. Drawing on both the junta’s self-appointed role of saviors and the benevolence of nurture, Catholic couples had thus rescued children from irresponsible “subversive” parents. In their struggle against state terror Abuelas’ metaphor apropiación resignified nurture as violence, pushing politico-cultural change towards a universal right to identity.
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Czajkowska, Aleksandra, Katarzyna Guzinska-Ustymowicz, Anna Pryczynicz, Dariusz Lebensztejn e Urszula Daniluk. "Are Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 Useful as Markers in Diagnostic Management of Children with Newly Diagnosed Ulcerative Colitis?" Journal of Clinical Medicine 11, n.º 9 (9 de maio de 2022): 2655. http://dx.doi.org/10.3390/jcm11092655.

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Matrix Metaloproteinase-9 (MMP-9) and Tissue Inhibitor of Metaloproteinase-1 (TIMP-1), enzymes involved in tissue remodelling, have been previously reported to be overexpressed in the colonic mucosa of patients with Ulcerative colitis (UC). The aim of this study was to determine the relation of MMP-9 and TIMP-1 with UC phenotypes, the disease activity index and routinely tested inflammatory markers in newly diagnosed paediatric patients. The study group comprised 35 children diagnosed with UC and 20 control groups. Serum and faecal concentrations of MMP-9 and TIMP-1 were estimated using enzyme-like immunosorbent assay kits and correlated to the disease activity index (Paediatric Ulcerative Colitis Activity Index, PUCAI), UC phenotype (Paris Classification), inflammatory markers and endoscopic score (Mayo score). Children with UC presented with significantly higher serum and faecal concentrations of studied markers compared to the control group. Both serums, MMP-9 and TIMP-1, were higher in children with more extended and severe lesions in the colon. Furthermore, serum MMP-9 correlated with the Mayo score, Paris classification and C-reactive protein (CRP) levels. Serum TIMP-1 showed correlation with PUCAI, Paris Classification, CRP levels and the erythrocyte sedimentation rate. Serum and faecal levels of MMP-9 and TIMP-1 are useful in discriminating UC patients and non-invasive assessments of disease phenotypes. It seemed that simultaneous measurement of these proteins in combination with other common markers of inflammation could be applied in clinical practice.
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Sapkota, K., N. Ranjeet, P. R. Onta e P. Thapa. "The outcome of Radial Neck Fracture Treated with Closed/ Open Reduction and Retrograde Kirschner Wires Fixation in the Paediatric Age Group". Kathmandu University Medical Journal 20, n.º 4 (31 de dezembro de 2022): 467–71. http://dx.doi.org/10.3126/kumj.v20i4.54087.

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Background Radial neck fractures in children are rare injuries, representing 1 to 5% of all elbow pediatric fractures. Most of them are non-displaced or slightly displaced and treated conservatively. Severely displaced or angulated radial neck fractures (Judet type III and IV fractures or O’Brien type III radial neck fractures) requires surgical treatment. Objective To study the clinical and radiological outcomes of fractures following closed or open reduction and percutaneous intramedullary stabilization of the displaced radial neck fracture in children. Method There were 24 children with displaced radial neck fracture Judet type II, III and IV fractures O’Brien type II, III who underwent closed reduction and retrograde intramedullary stabilization with Kirschner wires. Functional outcomes were evaluated based on of Mayo Elbow Performance Score. Result The mean age of patients was 8.42 ± 1.82 years with boys 15(62.5%) and girls 9(37.5%) in number. An excellent result was seen in 5(20.8%) cases and good results in 15(62.5%) cases according to the Mayo elbow performance score. Analyzing a passive and active range of motion, 5 had excellent results, 15 had good results and 4 had fair results compared to the normal side. Radiological evaluation showed fracture healing in excellent or good alignment according to Ursei radiological evaluation classification. Conclusion Closed reduction and retrograde intramedullary Kirschner wires stabilization for the displaced radial neck fracture provide excellent clinical and radiological results with few complications.
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Bashir, Muhammad Kashif, Aisha Ishtiaq e Shazia Bashir. "Frequency and Etiology of Pediatric Trauma, Experience at Tertiary Care Hospital". National Journal of Health Sciences 7, n.º 3 (30 de setembro de 2022): 121–23. http://dx.doi.org/10.21089/njhs.73.0121.

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Abstract: Objectives: To determine etiology and spectrum of trauma in children and to make recommendations for its prevention. Materials and Methods: This Hospital based Retrospective observational study was conducted in Department of Pediatric Surgery King Edward Medical University / Mayo Hospital Lahore from March 2021 to February 2022. All patients presented in Pediatric Surgical emergency King Edward Medical University/ Mayo Hospital Lahore were included in this study. Data regarding age, gender, mechanism and severity of trauma and its management was analyzed and recorded on a prescribed Performa. Results: During the study period a total of 3850 patients having trauma were presented in pediatric surgical emergency. There were 2206 (57.3%) male patients and 1644 (42.7%) females with male to female ratio of 1.3:1. Majority of children affected were 8 to 10 years age. Burn trauma was noted in 2400 (62.3%) while 1450 (37.7%) patients have poly trauma due to different etiological factors. Regarding burn trauma, majority of patients 1620 (67.5%) were having scald burn injury. Pedestrians 260 (17.9%) hitting with motor vehicle was noted to be major mechanism of trauma. Conclusion: Motor vehicle collision is most common mechanism of pediatric trauma after pediatric burn injury. There is a need for parental education and strict implementation of traffic laws to prevent trauma at pediatric age group.
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Alexander, Erin, Donnchadh O'Sullivan, Devon Aganga, Sara Hassan, Samar H. Ibrahim e Imad Absah. "Fr401 CHOLESTASIS IS AN OMINOUS PROGNOSTIC MARKER IN CHILDREN REQUIRING ECMO: THE MAYO CLINIC EXPERIENCE". Gastroenterology 160, n.º 6 (maio de 2021): S—312. http://dx.doi.org/10.1016/s0016-5085(21)01466-9.

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Peterson, Ann, Jon Shallop, Colin Driscoll, Alyce Breneman, Julie Babb, Ruth Stoeckel e Lee Fabry. "Outcomes of Cochlear Implantation in Children with Auditory Neuropathy". Journal of the American Academy of Audiology 14, n.º 04 (abril de 2003): 188–201. http://dx.doi.org/10.1055/s-0040-1715726.

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Ten children who were diagnosed with auditory neuropathy were matched with ten children who were diagnosed with other etiologies. All twenty children received cochlear implants at the Mayo Clinic in Rochester, Minnesota. Various measures were used to compare the outcomes for the two groups. We compared the children's unaided and aided audiograms, and measures of threshold and comfort levels. Performance on age appropriate speech perception tests was measured. Electrically elicited auditory brainstem response, predicted Neural Response Telemetry thresholds, and visually detected electrical stapedius reflexes were compared. Parental report of cochlear implant benefit was evaluated using either the Meaningful Auditory Integration Scale or the Infant-Toddler Meaningful Auditory Integration Scale depending on the age of the child. We also compared educational placement and communication mode. The results of this study demonstrated that there were no important differences in cochlear implant benefit between the two groups. In light of these findings, we support the use of cochlear implants as a viable option for selected children with auditory neuropathy.
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Madan, Riya, Jennifer Pitts, Marc C. Patterson, Robin Lloyd, Gesina Keating e Suresh Kotagal. "Secondary Narcolepsy in Children". Journal of Child Neurology 36, n.º 2 (15 de setembro de 2020): 123–27. http://dx.doi.org/10.1177/0883073820954617.

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Secondary narcolepsy occurs as a consequence of lesions involving the hypothalamic region that subserve wakefulness. Although observations on the characteristics of secondary narcolepsy have been published in adults, information on this topic in children is sparse. This is a retrospective study of characteristics and outcome of secondary narcolepsy in children. The medical records of 10 children with this condition at Mayo Clinic, Rochester, were reviewed. Characteristics of the underlying neurologic disorder, narcolepsy subtype, multiple sleep latency tests, medications used and outcome were extracted. Age at diagnosis of narcolepsy was between 6 and 17 years. Five of 10 patients had onset of excessive sleepiness within 1 year of diagnosis of the primary neurologic disorder. Six of 10 patients had type 1 narcolepsy (with cataplexy) whereas 4/10 had type 2 (without cataplexy). The clinical course was variable, with 8/10 continuing to require treatment for sleepiness at a mean period 6.6±6.2 years after diagnosis. One patient with narcolepsy type 1 due to Niemann Pick type C disease had died. One patient with narcolepsy type 2 due to craniopharyngioma had spontaneous remission of sleepiness. The 5/10 patients surviving with narcolepsy type 1 have continued to require pharmacotherapy for both sleepiness and cataplexy. This study draws attention to an important chronic sequel of childhood brain lesions that has variable, etiology-specific outcome. The rare occurrence of spontaneous resolution of childhood narcolepsy symptoms, not previously described, is also discussed.
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Gupta, Nidhi, Michael Rivera, Paul Novotny, Vilmarie Rodriguez, Irina Bancos e Aida Lteif. "Adrenocortical Carcinoma in Children: A Clinicopathological Analysis of 41 Patients at the Mayo Clinic from 1950 to 2017". Hormone Research in Paediatrics 90, n.º 1 (2018): 8–18. http://dx.doi.org/10.1159/000488855.

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Background/Aims: Adrenocortical carcinoma (ACC) is an aggressive childhood cancer. Limited evidence exists on a definite histopathological criterion to differentiate ACC from adrenocortical adenoma. The aim of this study was to investigate the clinicopathological data of children with ACC, identify prognostic factors, and validate a histopathological criterion to differentiate ACC from adrenocortical adenoma. Methods: This retrospective cohort included 41 children, followed at the Mayo Clinic from 1950 to 2017 (onset of symptoms ≤21 years). Outcomes of interest were: alive with no evidence of disease, alive with evidence of disease, and dead of disease. Results: Median age at onset of symptoms was 15.7 years (n = 41; range, 0.2–21 years). Female:male ratio was 3.6: 1. Mixed symptomatology (> 1 hormone abnormality) was the most common presentation (54%, n = 22). Sixty-six percent of patients (n = 27 out of 41) underwent total adrenalectomy. Metastatic disease was more common in children aged > 12 years (p = 0.002 compared to < 4 years). The most common sites of metastases were the liver and lungs. Overall 2-year and 5-year survival rates were 61% (95% CI 45–77) and 46% (95% CI 30–62), respectively. Metastasis at the time of diagnosis was independently associated with poor prognosis (risk ratio 13.7%; 95% CI 3.9–87.7). Weiss criteria (29%) and modified Weiss criteria (33%) were less accurate in younger patients (< 12 years), compared to the Wieneke index (100%). Conclusion: The presence of metastases was an independent prognostic factor. The Wieneke index was the most accurate in predicting clinical outcomes in younger children.
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Gaël Bita, André Izacar, Benjamin Azike Chukuwchindun, Thomas Eddy Biwole Omgba, Agbor Nyenty Agbornkwai, Justin Bienvenu Eyong e Martin Sobze Sanou. "Qualitative Analysis of the Determinants of Malnutrition Among Children Under-five in Households in the Mayo-Danay Department, Cameroon". Budapest International Research in Exact Sciences (BirEx) Journal 3, n.º 1 (24 de dezembro de 2020): 755–66. http://dx.doi.org/10.33258/birex.v3i1.1500.

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The Far North region has the highest rate of chronic malnutrition (35.9%) ahead of East (35.4%); North (30.6%) and Adamawa (28.7%). The study aimed to identify contextual factors of child malnutrition in line with UNICEF’s causal pattern of malnutrition (2013). This was a qualitative study. Multiple case sampling of social micro-units was used. Focus-groups; face-to-face interviews and observations were organized. Seguin method was used for data analysis (2010). Fifty people participated in the study. Mayo-danay is a landlocked area, where the lack of food processing and food conservation infrastructure promotes early and low-cost liquidation of food products. A situation that exposes families to famine and poverty a few months after the harvest. The influx of internally displaced persons (IDPs); insecurity due to terrorism has weakened cross-border trade. The household size is up to 10 members, that did not allow children to eat at their convenience, and in a diverse way. The Christian head of households did not systematically contribute to the food ration, unlike the Muslims. Fish, agricultural and livestock products are more for sale than for consumption in the household. There are frequent shortages of food supplements for the management of malnutrition in health training. The causes of malnutrition in Mayo-Danay were multifactorial. Strategies to fight against malnutrition must take into account the integrated approach to local and sustainable development.
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Gleich, Stephen J., Randall Flick, Danqing Hu, Michael J. Zaccariello, Robert C. Colligan, Slavica K. Katusic, Darrell R. Schroeder et al. "Neurodevelopment of children exposed to anesthesia: Design of the Mayo Anesthesia Safety in Kids (MASK) study". Contemporary Clinical Trials 41 (março de 2015): 45–54. http://dx.doi.org/10.1016/j.cct.2014.12.020.

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Laino Sanchis, Fabricio. "Fugitive perpetrators, children disappeared twice: transnational activism and diplomatic conflicts in times of transition (Argentina, Uruguay, Paraguay: 1984-1996)." Clepsidra - Revista interdisciplinaria de Estudios sobre Memoria 11, n.º 21 (2 de abril de 2024): 15–38. http://dx.doi.org/10.59339/c.v11i21.608.

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Tras el final de la última dictadura en Argentina, la organización Abuelas de Plaza de Mayo pudo localizar y denunciar a varios represores que tenían en su poder a niños apropiados durante la represión ilegal. Algunos de estos lograron fugarse con los niños apropiados a Paraguay, donde gozaron de protección del régimen militar vigente de Alfredo Stroessner. A partir de ese momento, se abrió un intenso conflicto por su extradición, que tuvo implicancias políticas, diplomáticas y judiciales a nivel nacional, regional e internacional. En este artículo nos centramos en el activismo por la extradición de estos represores y la restitución de esos niños y niñas apropiados/as. Nos interesa, en primera instancia, mostrar el repertorio de acción y las múltiples escalas (nacional, regional y trasnacional) en las que se desenvolvió esta causa, que tuvo a Abuelas de Plaza de Mayo como principal promotora, pero que reunió también a familiares uruguayos y contó con apoyos múltiples en otros países de la región y de Europa. Analizaremos de qué manera este activismo transnacional logró movilizar a su favor a los organismos internacionales de derechos humanos, lo que a su vez condujo a presiones sobre los gobiernos y conflictos interestatales. En última instancia, a través del análisis de este caso buscaremos vislumbrar algunos aspectos de la trama regional del complejo proceso de democratización regional en una década en la que coexistieron en el Cono Sur regímenes y transiciones de carácter muy diverso.
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Joshi, Ruban Raj, e Gabriel David Sundararaj. "Clinical Results of Surgically Treated Medial Humeral Epicondylar Apophyseal Avulsion Injury in Children and Adolescent." Journal of Lumbini Medical College 2, n.º 2 (30 de dezembro de 2014): 31. http://dx.doi.org/10.22502/jlmc.v2i2.54.

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Introduction: Fractures of the medial humeral epicondyle represent approximately 10% of all paediatric elbow fractures. Objective of our study was to assess treatment outcomes of children and adolescent with medial epicondylar fracture of the elbow using standard operative protocols. Methods: 20 surgically treated fractures of the medial humeral epicondyle were analysed & reviewed for their epidemiological, clinical and surgical parameters. A valgus stress test was performed under general anesthesia or sedation. All patients underwent open reduction internal fixation using a similar technique. The medial epicondylar fragment was anatomically reduced and fixed in all cases with screws, Kirshner wires or tension band wiring. At final evaluation, union (radiologically) and elbow function [MAYO elbow performance score (MEPS)] was assessed. Results: An evaluation of all of our patients after a mean follow-up of 8.75 months (SD=4.76) after initial surgery was possible. The mean age of patients at the time of injury was 10.8years (SD=2.3). Fifteen (75%) dominant elbows were injured in our study and 12(60%) elbows had an associated elbow dislocation. On examination in operating room post anaesthesia, all of the elbow injuries revealed some degree of valgus instability. All of our patients(n=20) showed good to excellent results in the MAYO elbow performance score (MEPS). Radiographically, union was achieved in all cases. Three patients developed postoperative ulnar nerve neuropraxia, all recovered at time of final follow up. One patient developed mild lateral heterotrophic ossification but did not require any additional surgical intervention. Conclusion: Our results suggest that open reduction internal fixation of displaced medial epicondyle fractures leads to satisfactory motion and function. A valgus stress test in operating room can reveal the true nature of joint instability that can warrant operative stabilization of medial epicondylar injuries.
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Kuloor, Subraya B., Abdul J. Shareef e Anupam Sudeep. "Medial epicondyle fractures in children: a study of functional outcome of surgical fixation". International Journal of Research in Orthopaedics 5, n.º 1 (25 de dezembro de 2018): 55. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20185056.

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<p class="abstract"><strong>Background:</strong> Medial epicondyle fracture is a common elbow injury in children. It is associated with elbow dislocation in many cases. Treatment of displaced medial epicondyle fracture with and without elbow dislocation is a debated topic. Surgical and non surgical methods are practiced with variable results.</p><p class="abstract"><strong>Methods:</strong> Our study was a prospective study of medial epicondyle fractures treated by surgical fixation with k wires. We studied total of 24 cases out of which 15 had elbow dislocation. The study period was from 2012 to 2015 and indications for surgery were displacement more than 5 mm, elbow instability, incarceration of fragment, ulnar nerve irritation. Open reduction and internal fixation with K wire done. We used joystick method while reducing the fragment with k wire which was a great help. We assessed the cases using mayo elbow performance score.<strong></strong></p><p class="abstract"><strong>Results:</strong> Our study yielded excellent results in 92% of patients (mayo elbow performance score &gt;90). There was no major difference in clinical outcome between two groups of patients. Complications like instability and non-union not seen following surgical fixation with K wires. The mean loss of flexion, extension, supination, and pronation was 4, 5, 3 and 2 degrees respectively with elbow dislocation group and 2, 3, 1, 1 in without dislocation group. Pre op instability seen in 54% patients was absent in follow up period. Stiffness was more in elbow dislocation group but overall performance was almost equal.</p><p class="abstract"><strong>Conclusions:</strong> Surgical fixation of medial epicondyle fractures yields excellent results and may be advisable when indicated.</p>
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Damien, Noma Eloundou, e Pr Mebenga Tamba Luc. "The Dynamics of Caring for the Education of Internally Displaced School-Age Children: Teaching During a Crisis in the Mayo Tsanaga Department". East African Scholars Journal of Education, Humanities and Literature 7, n.º 03 (21 de março de 2024): 119–29. http://dx.doi.org/10.36349/easjehl.2024.v07i03.004.

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Objective: The aim of this article is to examine the changes made by stakeholders in the provision of education for internally displaced school-age children during periods of crisis in the Department of Mayo Tsanaga. Method: Data was collected using development anthropology techniques from basic education authorities responsible for the education of displaced school-age children, implementing partners, parents or families of IDPs, pupils and informants likely to provide relevant information on this target group in the department of Mayo Tsanaga. The data was collected during the writing of our PhD thesis in Anthropology. Documentary research was also carried out. A total of 20 in-depth interviews were conducted in the locality of Zamai and surrounding villages with a split between urban and rural areas over a period from 15 November 2021 to the present day. Results: It has been shown that controlling the numbers of these displaced persons is a prerequisite for better planning and better integration into the education sector. The different forms of education will not eliminate the risk of conflict between individuals or groups of individuals, but they will enable people to know how to manage them and prevent them from degenerating into armed conflict, civil war or even genocide. Discussion: The particularity of this article is that, as well as being situated between forced displacement, terrorism and formal education, it takes a holistic look at the measures taken by stakeholders to encourage or compel parents to contribute to their children's education despite the hostilities, insecurity and armed conflicts that have arisen. Conclusion: The IDPs who are the subject of this study come from surrounding villages and Districts, with different cultures and differing apprehensions about formal education for their children.
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Romanchishen, Anatoly Filippovich, e B. Thompson Geoffrey. "Comparative results of treatment of children and adolescents with thyroid cancer at St. Petersburg Endocrine Surgery Centre and Mayo Clinic". Pediatrician (St. Petersburg) 6, n.º 1 (15 de março de 2015): 38–43. http://dx.doi.org/10.17816/ped6138-43.

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Introduction. Thyroid cancer (TC) is the most often malignant tumor in childhood and made 1.5-3.0 % of all children population or 45.3 % of pediatric endocrine epithelial cancers. A lot of questions concerning to volume of thyroid surgery, postoperative radioiodine therapy needs to be discussed. Material and methods. During 1970-2011 in the Center (1 group) were operated 105 TC children and adolescent (up to 18 yeas) and in Mayo Clinic - 188 (2 group) in period 1940-2000. Since of 80-s in those clinics were used the same perioperative examinations, like TSH, T4, T3 blood levels, USG, fine needles aspiration biopsy, CT and morphological examinations. Results and discussion. Average age of the Center and Rochester patients was the same and achieve 16.3 ± 0.3 and 16.0 ± 0.5, accordingly. In both groups has prevailed girls: in the 1 group they made 73.3 % (M : F 1 : 2.7) and in the 2 - 70.7 % (M : F 1 : 2.4). Childhood differentiated TC were associated with aggressive behavior: regional metastases were found in 53.0 % and 81.4 %, extrathyroid TC spreading - in 9.6 and 19.7 %, distant metastases - in 9.6 and 4.8 %, accordingly. In our Center we have performed hemithyroidectomies and subtotal thyroidectomies in 58.1 % with ipsilateral central neck dissection (CND). In Mayo Clinic in all TC cases were performed thyroidectomy (TE) since 1950. TC relapses we have no observed in 1 group and they have place in 6.9 % 2 group patients, recurring lymphatic metastases - in 8.4 % and 20.7 %, accordingly. Radioiodine therapy (RIT) has performed in 21.1 % and 25.5 % operated children. In 1 group 95 (96.0 %) of 99 operated were alive during 5-36 years, in the 2 - only in two cases reason of death was TC, but in 14 - other malignant tumor. Conclusion. Childhood TC is associated with more locally aggressive and more frequent distant disease than its adult counterpart. Recurrence rates tend to be higher in children, but cause-specific mortality remains low. Optimal initial treatment of childhood TC should include TE and CND. RIT in childhood has increased possibility of others malignant tumor in follow up period.
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Rafique, Akkad, Kamran Saeed, Mehtab Ali, Tauseef Ahmed Baluch, Hafiz Ahmed Fayyaz Bajwa e Syed Faraz Ul Hassan Shah Gillani. "Different Causes and its Association in Children with Cerebral Palsy". Pakistan Journal of Medical and Health Sciences 16, n.º 8 (31 de agosto de 2022): 167–68. http://dx.doi.org/10.53350/pjmhs22168167.

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Aim: To assess the different causes and their association of cerebral palsy in children. Methods: We conducted this cross-sectional survey using consecutive sampling technique at the orthopedic surgery department Mayo hospital, Lahore from October 2011 to November. The sample size was 200 children of all age groups, on history and clinical examination who were diagnosed with cerebral palsy were included in the study and children or their parents refused to participate in the study were excluded. Results: Out of the total 200 children, 42(21%) had <1year of age, 80(40%) has 1-5 year age, 62(31%) has 5-15 year and 16(8%) had reached the skeletal maturity. Majority, 130(65%) were boy and 70(35%) were girls. None of the participant was married till study completion. When education status was asked, majority 127(63.5%) were illiterate and 28(14%) children were admitted in nursery, 27(13.5%) had primary education, 13(6.5%) completed the matriculation and only 5(2.5%) children were enrolled as undergraduate. Conclusion: Low socioeconomic status and illiterate population were in majority. Most children had age up to five years with one third of the children had associated illness. Keywords: Cerebral palsy, congenital disease, central nervous system, motor impairment syndrome, gait analysis.
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Madigan, Theresa, Nipunie Rajapakse e Robin Patel. "1108. Diagnostic Yield of the BioFire FilmArray Gastrointestinal Panel in Hospitalized Children at an Academic Children’s Center". Open Forum Infectious Diseases 5, suppl_1 (novembro de 2018): S332. http://dx.doi.org/10.1093/ofid/ofy210.942.

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Abstract Background The BioFire FilmArray Gastrointestinal Panel (BioFire Diagnostics) (GIP) is a multiplex stool PCR test that detects 22 organisms. Studies in adults suggest that the diagnostic yield of the GIP in hospitalized patients is low. The utility of the GIP among hospitalized pediatric patients and indications for diagnostic stewardship of this test are not well described. Methods We conducted a retrospective chart review of hospitalized pediatric patients who had a GIP ordered between October 2015 and October 2017. Demographic, clinical, and laboratory information was extracted from the medical record. Statistical analysis was completed using JMP Pro 13.0.0 (SAS Institute Inc.). Results Over the 2-year study period, 193 GIPs were obtained on 155 individual pediatric patients. The mean patient age was 8 years and 59% were male. Forty-four percent of patients were immunocompromised and 21% had inflammatory bowel disease. The pediatric infectious disease (PID) team was consulted in 15% of patients at the time the test was ordered. The overall positivity rate of the GIP for one or more pathogens was 42% (Figure 1), with 76% of GIPs positive for one, 23% for two, and 1% for three pathogens. No parasitic infections were diagnosed. The GIP was more likely to be positive if GI symptom onset was prior to admission (48% vs. 24%, P = 0.004), if GI symptoms had been present for &lt; 2 weeks vs. ≥2 weeks (52% vs. 20%, P = 0.0001), and if GI symptoms were the primary reason for the hospital admission (50% vs. 32%, P = 0.012). Only Clostridioides difficile or viral pathogens were detected in patients whose symptoms began in the hospital (Figure 2). Among patients with a positive test, 40% received treatment targeted at one or more of the detected pathogens (Figure 1). Enteropathogenic E.coli (EPEC) and Enteroaggregative E.coli (EAEC) were never treated (Figure 3). Conclusion The GIP was positive for one or more pathogens in 42% of hospitalized children for whom the test was ordered, and led to specific therapy in 40% of those with a positive test. EPEC and EAEC were not treated. The diagnostic yield of the GIP was higher if GI symptoms were present for &lt;2 weeks, began before hospitalization, and were the primary reason for admission. The GIP was frequently obtained without guidance from the PID team. Disclosures R. Patel, CD Diagnostics, BioFire, Curetis, Merck, Hutchison Biofilm Medical Solutions, Accelerate Diagnostics, Allergan, and The Medicines Company: Grant Investigator, Research grant – monies paid to Mayo Clinic. Curetis, Specific Technologies, Selux Dx, GenMark Diagnostics, PathoQuest and Genentech: Consultant and Scientific Advisor, Consulting fee – monies paid to Mayo Clinic. ASM and IDSA: Travel reimbursement and editor’s stipends, Travel reimbursement and editor’s stipends. NBME, Up-to-Date and the Infectious Diseases Board Review Course: Varies, Honoraria. Mayo Clinic: Employee, Salary.
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Reimer, Ronald, e Burton M. Onofrio. "Astrocytomas of the spinal cord in children and adolescents". Journal of Neurosurgery 63, n.º 5 (novembro de 1985): 669–75. http://dx.doi.org/10.3171/jns.1985.63.5.0669.

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✓ The authors review 32 cases of spinal cord astrocytoma in patients under 20 years of age who were treated at the Mayo Clinic between 1955 and 1980. There was a 1.3:1 male to female ratio. Twenty patients were between 6 and 15 years of age at the time of diagnosis. The duration of symptoms prior to definitive diagnosis varied from 5 days to 9 years, with an average of 24 months. The most common symptoms were pain (62.5%), gait disturbance (43.7%), numbness (18.8%), and sphincteric dysfunction (18.8%). The most common neurological findings were a Babinski response (50.0%), posterior column sensory dysfunction (40.6%), and paraparesis (37.5%). A median follow-up period of 8.6 years (range 0.8 to 25.5 years) revealed that the survival time diminished with increased histological grade of the astrocytoma (p < 0.001). The development of postlaminectomy spinal deformities represented a serious postoperative complication. This occurred in 13 patients and was first recognized between 8 and 90 months postoperatively. Six deformities occurred following cervical laminectomy, and eight patients required at least one orthopedic procedure. It is crucial to follow these patients for an extended period of time to watch for postoperative spinal deformities.
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Ip, D., e WL Tsang. "Medial Humeral Epicondylar Fracture in Children and Adolescents". Journal of Orthopaedic Surgery 15, n.º 2 (agosto de 2007): 170–73. http://dx.doi.org/10.1177/230949900701500209.

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Purpose. To assess treatment outcomes of young patients with medial epicondylar fracture of the elbow using standard operative protocols. Methods. 24 consecutive patients with medial humeral epicondylar fracture underwent surgery by one of the 3 methods: (1) 2 parallel Kirschner wires, (2) 2 parallel Kirschner wires plus a tension-band wire, and (3) a screw plus an anti-rotation Kirschner wire. Fractures displaced less than 5 mm were treated conservatively (casting for 3 weeks). Outcome was assessed clinically and radiologically. The Mayo Clinic Elbow Performance Index was measured. Results. The 3 patients with undisplaced fractures had good radiological results and scores. One patient with a displaced fracture refused surgery and subsequently developed pseudarthrosis and cubitus valgus. All operatively treated patients had good scores, but 2 treated with 2 parallel Kirschner wires alone developed pseudarthrosis. Patients in this group needed longer rehabilitation to attain a functional range of movement than those in other groups (treated together with a tension-band wire or screw). Conclusion. Surgery is recommended for children with displaced medial epicondylar fractures of more than 5 mm. The use of a tension-band wire, instead of a screw, together with Kirschner wires is the preferred treatment for younger children.
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Naz, Shagufta, Nimrah Fiaz Sandhu, Eesha Sajjad, Saima Sharif e Iram Arshad. "Prevalence of Congenital Cataract and Lens Extraction in Lahore Population". Lahore Garrison University Journal of Life Sciences 6, n.º 03 (15 de setembro de 2022): 216–26. http://dx.doi.org/10.54692/lgujls.2022.0603224.

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Congenital cataracts account for one-third of infant blindness globally and are one of the leading cause of vision loss in children. A retrospective study was performed between October 2020 and April 2021 on congenital cataract patients of Lahore visited ophthalmologic consultation at the Al Ehsaan eye hospital, General Hospital and Mayo hospital. The purpose of the study was to find the prevalence of congenital cataract in children. About 100 cases of congenital cataract including both male and female children were identified from age group of 1-13years. Congenital cataract was diagnosed using Snellen’s visual acuity test, ophthalmoscope and slit lamp test. Male children showed greater prevalence of congenital cataract as compared to female children. The prevalence of congenital cataract in male children was 55% (n=55) while among female children, it was 45% (n=45). Both conditions of unilateral and bilateral congenital cataract were observed with incidence of 46% (n=46) and 54% (n=54) in male and female children respectively. Lens extraction was also done in 94% (n=94) and after surgery 55% (n=52) patients showed positive response and 45% (n=42) patient had negative response for light perception. Moreover, most patients of congenital cataracts were of less than 1 year of age group. It was concluded congenital cataract may lead to childhood blindness if not treated on time.
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de Plaza de Mayo, Madres. "No truth, no justice". Index on Censorship 25, n.º 5 (setembro de 1996): 132–36. http://dx.doi.org/10.1177/030642209602500524.

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Just a few blocks from the Buenos Aires' Congress building, where the street narrows again, the Madres de Plaza de Mayo have their office. Tourists pass by without noticing the building with its small brass plaque reading ‘House of the Mothers’. Every day the Mothers meet here to continue their 20-year struggle, begun during the military dictatorship (1976-1983), to establish exactly what happened to their disappeared sons and daughters and to demand retribution against those who imprisoned, tortured and killed their children. July this year marked their 1,000th meeting. There are also the Grandmothers, women who lost not only a daughter or son, but also their children's children. Some of these were separated from their mothers and killed, others were given for adoption and, to this day, have no idea of their real parents. Ingo Malcher talked to them for Index
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Jandric, Slavica, e Ksenija Boskovic. "Functional outcome of posttraumatic elbow contractures". Medical review 63, n.º 7-8 (2010): 546–49. http://dx.doi.org/10.2298/mpns1008546j.

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Introduction. Posttraumatic elbow contractures can cause functional limitations and impairment of activities of daily living in children and adults. The aim of this study was to investigate the outcome and differences between posttraumatic elbow contractures in children and adults during rehabilitation. Material and methods. We analyzed 68 patients with posttraumatic elbow contractures, who had been admitted to the regional rehabilitation center and managed by procedures of physical therapy. All patients were divided into two groups: group A (34 children) and group B (34 adults). Mayo Clinic Performance Index for Elbow (MCPI) was measured at the beginning and at the end of the physical treatment for each patient. Results. Out of the study sample, 76.47% of children and 47.06% of adult patients had excellent score at the end of the therapy. The median of Performance index increased for both groups after the physical therapy and the differences were significantly high for both groups, children (t=5.66, p<0.001) and adults (t=2.47, p<0.001). MCPI at the discharge was significantly higher in the children than in the adults (t=2.85, p<0.05). Conclusion. The results of our investigation have shown that the elbow function assessment in patients with posttraumatic elbow contractures (in regard to pain, motion, stability and sum of daily function) was better in children than in adults at discharge, after approximately 3 weeks of rehabilitation.
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Warner, Mark A., Mary E. Warner, David O. Warner, Louise O. Warner e Jackson E. Warner. "Perioperative Pulmonary Aspiration in Infants and Children". Anesthesiology 90, n.º 1 (1 de janeiro de 1999): 66–71. http://dx.doi.org/10.1097/00000542-199901000-00011.

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Background Pulmonary aspiration of gastric contents during the perioperative period in infants and children may be associated with postoperative mortality or pulmonary morbidity. There has not been a recent determination of the frequency of this event and its outcomes in infants and children. Methods The authors prospectively identified all cases of pulmonary aspiration of gastric contents during the perioperative courses of 56,138 consecutive patients younger than 18 yr of age who underwent 63,180 general anesthetics for procedures performed in all surgical specialties from July 1985 through June 1997 at the Mayo Clinic. Results Pulmonary aspiration occurred in 24 patients (1: 2,632 anesthetics; 0.04%). Children undergoing emergency procedures had a greater frequency of pulmonary aspiration compared to those undergoing elective procedures (1:373 vs. 1:4,544, P &lt; 0.001). Fifteen of the 24 children who aspirated gastric contents did not develop respiratory symptoms within 2 h of aspiration, and none of these 15 developed pulmonary sequelae. Five of these nine children who aspirated and in whom respiratory symptoms developed within 2 h subsequently had pulmonary complications treated with respiratory support (P &lt; 0.003). Three children were treated with mechanical ventilation for more than 48 h, but no child died of sequelae of pulmonary aspiration. Conclusions In this study population, the frequency of perioperative pulmonary aspiration in children was quite low. Serious respiratory morbidity was rare, and there were no associated deaths. Infants and children with clinically apparent pulmonary aspiration in whom symptoms did not develop within 2 h did not have respiratory sequelae.
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Bilal, Ökkeş, Ali Murat Kalender, Burçin Karslı, Volkan Kılınçoğlu, Mustafa Kınaş e Nuh Dündar. "Radiological and functional outcomes of modified Metaizeau technique in displaced radial neck fractures". Acta Orthopaedica Belgica 87, n.º 2 (30 de junho de 2021): 235–41. http://dx.doi.org/10.52628/87.2.05.

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The management of displaced radial neck fractures in children is still a controversial topic. The objective of this study is to examine the outcomes of modified Metaizeau technique in the children with displaced radius neck fractures. The retrospective study included 15 children with displaced radial neck fracture with an angulation of more than 30° who were managed with the use of leverage technique by mosquito clamps and internal fixation with elastic stable intramedullary nailing (ESIN). Radiological and functional assessments were performed during follow-up. Additionally, the patients were evaluated using Mayo Elbow Per- formance Score (MEPS). All the children could be managed with clamp-assisted closed reduction. The average duration of follow up was 25.5 ± 6.1 months (15-36 months). An excellent elbow function was achieved in all but one patient. Based on Metaizeau classification, excellent, good, fair, and poor outcomes were achieved in 11, 1, 2, and 1 patients, respectively. The average postoperative MEPS score was 98.7 ± 5.1 (80-100). Clamp-assisted closed reduction and fixation with ESIN is a good choice in the children with displaced radial neck fractures. This technique is associated with good functional and radiologic outcomes in the medium-term. Further studies are warranted with larger sample sizes.
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Sanou Martin, Sobze, Bita Andre Izacar Gaël, Djeunang Dongho Ghyslaine Bruna, Sieleunou Isidore e Nkengfack Nembongwe Germaine Sylvie. "Food Profiles and Exposure to Acute Malnutrition among Children Under-five in the Department of Mayo-Danay, Cameroon". Journal of Food and Nutrition Research 7, n.º 11 (19 de novembro de 2019): 759–65. http://dx.doi.org/10.12691/jfnr-7-11-1.

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ALIÇ, Taner. "Is it possible to reduce treatment costs in distal radius torus fractures?" Journal of Medicine and Palliative Care 4, n.º 1 (10 de fevereiro de 2023): 28–33. http://dx.doi.org/10.47582/jompac.1212503.

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Aim: The aim of the study was to evaluate the effect of parental information on the number of radiological examinations, the number of orthopedics outpatient visits, the duration of early orthopedic outpatient admission, the fracture recovery scores of reduction, and the cost of treatment of torus fractures in children in in the emergency service.Material and Method: A total of 85 patients having stable torus fractures, aged between 0-16 years have been included to the longituidinal study during the period of first of April 1, 2020 and first of September, 2022. A total of 44 patients whose parents are not informed were evaluated in the emergency department and were transfered to the Orthopedics polyclinic (No Information group- No-INF), whereas 41 patients were evaluated by the Orthopedist in the emergency department and their parents were informed directly (Information group- INF). The groupd were compared in terms of the duration of the first admission to the orthopedic polyclinic, the number of applications to the orthopedic polyclinic, the number of radiological examinations performed, whether reduction has been performed, fracture healing scores and current treatment costs and correlation was analyzed. Results: The MAYO Wrist Score (p=0.80), age (p=0.712), gender (p=0.815), and complications (p=0.482) did not differ significantly between the No-INF and INF groups. Patients in the INF group whose parents have been directly informed in the emergency department had lower orthopedic polyclinic application rates (p&lt;0.001), longer delay for the first orthopedic polyclinic admission (p&lt;0.001) and a lower probability and/or less number of X-Ray evaluation(p&lt;0.001). Correlation between the variables such as Patient’s Modified MAYO Wrist Scores, the number of orthopedic polyclinic visits, the first orthopedic polyclinic admission time, the reduction procedure and the number of X-Rays was not ststistically significant (p&gt;0.05). Findings show that additional tests and procedures such as radiography has increased the costs of 6-41% in the present study. Conclusion: It can be concluded that adequate information in the emergency services for parents of children with stable torus fractures might provide a reduction in treatment costs due to lower orthopaedic polyclinic admission and reduced radiographic examination. Wrist MAYO scores have not been affected application of reduction, radiographic evaluation, polyclinic admission and time.
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Iqbal, Javed, Ghazala Firdous, Hafiz Muhammad Imran Aziz, Syed Faisal Usman, Muhammad Afzal, Muhammad Sharif, Fatima Naumeri e Kashif Bashir. "Major Trauma and the use of Tranexamic Acid in Children". Pakistan Journal of Medical and Health Sciences 17, n.º 5 (30 de maio de 2023): 468–70. http://dx.doi.org/10.53350/pjmhs2023175468.

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Objective was to determine reduction in blood loss in children with major trauma with or without using Tranexamic acid Methods: A study included 260 patients admitted to pediatric surgery departments at Mayo Hospital, Children's Hospital, and Jinnah Hospital in Lahore, from September, 2018 to April, 2019. Patients were divided into Tranexamic acid and control groups. Both groups received standard treatment and blood transfusion requirements. Patients were followed for length of stay and final outcomes. Results: Mean injury severity score in case and control groups was 26.61±11.17 and 29.00±11.64 respectively. Mean hospital stay was significantly shorter (p = 0.002], massive blood transfusions were significantly low [3.8% vs. 38.46%, p-value<0.001] and need of surgery [24.6% vs. 46.15%, p <0.001]. Mortality rate 1.54% vs. 7.69%, p =0.018 and discharge rate 98.64% vs. 92.31%,p = 0.018). Blood transfusion requirement and need of surgery were significant predictors for mortality in this study. Conclusion: Results of this study demonstrate that Tranexamic Acid can be effectively used to minimize blood transfusion requirement in children with major trauma. It effectively reduces the need of massive blood transfusion, minimizing mortality and shortens the hospital stay for pediatric patients. Keywords: Tranexamic acid, Effectiveness, Blood loss, Children, Trauma
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Sumarwoto, Tito, Seti Aji Hadinoto, Herlambang Pranandaru, Hanif Andhika, Сholahuddin Рhatomy e Pamudji Utomo. "Short-term Follow-up of Early Reconstructive Surgery Management in Neglected Supracondylar Humeral Fractures". Open Access Macedonian Journal of Medical Sciences 9, B (5 de janeiro de 2021): 24–28. http://dx.doi.org/10.3889/oamjms.2021.5577.

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BACKGROUND: The supracondylar humeral fracture is a fracture located in the proximal position of the trochlea and humeral capitulum. This fracture is the most common elbow fracture in children. Epidemiological research states that these fractures constitute 58% of all elbow fractures in children. It is also mentioned that 10–20% patients undergo belated admission to get therapy. Based on the literature, the fracture is categorized as neglected if the fracture treatment is 14 days post-trauma. Unfortunately, few reports can provide management guidelines. Some experts mention the “wait and see” attitude toward this fracture until a perfect remodeling happens to correct the deformity; however, a number of studies have shown good results after early reconstruction. AIM: We aimed to evaluate the short-term follow-up of supracondylar humeral fractures that came after 14 days of injury and then open reduction reconstructions were done, followed by the installation of K-wire and screws with the figure of eight patterns based on the quick disabilities of the arm, shoulder, and hand (Q-DASH) 9-score, Flynn’s Criteria, and Mayo Elbow Performance Score (MEPS). METHODS: The samples were five patients who underwent corrective open reduction and injury fixed with Kirschner (K)-wire and screws with the figure of eight patterns using the posterior approach at the Orthopedic Hospital from December 2019 to February 2020. Results were assessed with the quick disabilities of the arm, shoulder, and hand-9 score (Q-DASH-9 score), Flynn’s Criteria, and Mayo Elbow Performance Score (MEPS). RESULTS: All patients after reconstruction correction showed an increase in range of motion in the fractured elbow. No complications were found from the surgical treatment. CONCLUSIONS: Early reconstruction correction of patients with supracondylar humeral fractures gave satisfactory results based on the Q-DASH-9 Score, Flynn’s Criteria, and MEPS.
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