Artigos de revistas sobre o tema "Maria Rosenberg"

Resenha de: YALOM, Irvin D. O enigma de Espinosa: a história do filósofo judeu que influenciou uma das maiores mentes nazistas. Tradução Maria Helena Rouanet. 1ªEd. Rio de Janeiro: Harper Collins, 2019. 432p.

Noach Lasman, Wspomnienia z Polski 1 sierpnia 1944–30 kwietnia 1957, Warszawa 1997; Celina Budzyńska, Strzępy rodzinnej sagi, Warszawa 1997; Marek Urban, Polska… Polska…, Warszawa 1998; Oskar Kofler, Żydowskie dwory. Wspomnienia z Galicji Wschodniej od początku XIX wieku do wybuchu I wojny światowej, Warszawa 1999; Chawka Folman – Raban, Nie rozstałam się z nimi…, tłum. z hebrajskiego Inka Wajsbrot i Dora Sternberg, Warszawa 2000; Janina Bauman, Nigdzie na ziemi, Warszawa 2000; Irena Śmigielska, Skradzione lata, Warszawa 2001; Jakub Bukowski, Opowieść o życiu, Warszawa 2002; Leokadia Silverstein, Tak właśnie było, tłum. z angielskiego Hanna Sochacka-Kozłowska, Warszawa 2002; Florian Majewski, Pustelnik, Warszawa 2002; Lili Chuwis-Thau, A jeśli Cię zapomnę, Warszawa 2002; Menachem Katz, Na ścieżkach nadziei, tłum. z hebrajskiego Jan Biełas, Warszawa 2003; Joseph Rosenberg, Nazywam się Józef Nowak, Warszawa 2004; Rachela Margolis, Wspomnienia wileńskie, Warszawa 2005; Icchak Sternberg, Pod przybraną tożsamością, tłum. z hebrajskiego Maria Perlberger-Schmuel, Warszawa 2005; Eliasz Bialski, Patrząc prosto w oczy, Warszawa 2006

Our society new where technology has touched every cell of it is becoming even more virtually from where fashion is Selfie therefore be shooting themselves, a modern trend which has involved the whole society on the plates as Instagram, Facebook, Twitter, Snapchat, etc. Art selfie is one that many people have practiced and perfected over the years, but knowing what relationship they have with this new generation of virtual relationship remains a difficult task as important as well. This study aims to explore the selfie as a reflection of low self-esteem because the mania for photographing herself, is a pathology of the syndrome in search of a stable personality. Target group of this study were middle school students "Dhaskal Todri" in Elbasan, where 100 participants aged 16-18 years from where 39 participants were males and 61 females. They were asked to fill the Rosenberg Self-Assessment Inventory (Rosenberg Self-Esteem Inventory, 1965) within ethical standards. After analysis of the data showed a positive correlation between connectivity Selfie – Self-Esteem which holds that studies to date have shown that there is a connection between the selfie mania and self-esteem. Out of the sample obtained in this study show that individuals are looking for a better image of themselves as self images contradict the image of a secure existence, through fixing a few moments as a symbol of an attempt to establish an identity consistent, full realized. The pathology of this syndrome is the search for a stable personality. Of course, we are talking about the first research on this phenomenon should probably be more careful diagnostic categorization and labeling.

Our society new where technology has touched every cell of it is becoming even more virtually from where fashion is Selfie therefore be shooting themselves, a modern trend which has involved the whole society on the plates as Instagram, Facebook, Twitter, Snapchat, etc. Art selfie is one that many people have practiced and perfected over the years, but knowing what relationship they have with this new generation of virtual relationship remains a difficult task as important as well. This study aims to explore the selfie as a reflection of low self-esteem because the mania for photographing herself, is a pathology of the syndrome in search of a stable personality. Target group of this study were middle school students "Dhaskal Todri" in Elbasan, where 100 participants aged 16-18 years from where 39 participants were males and 61 females. They were asked to fill the Rosenberg Self-Assessment Inventory (Rosenberg Self-Esteem Inventory, 1965) within ethical standards. After analysis of the data showed a positive correlation between connectivity Selfie – Self-Esteem which holds that studies to date have shown that there is a connection between the selfie mania and self-esteem. Out of the sample obtained in this study show that individuals are looking for a better image of themselves as self images contradict the image of a secure existence, through fixing a few moments as a symbol of an attempt to establish an identity consistent, full realized. The pathology of this syndrome is the search for a stable personality. Of course, we are talking about the first research on this phenomenon should probably be more careful diagnostic categorization and labeling.

Abstract Fanconi anemia (FA), a model syndrome of genome instability, is caused by a deficiency in DNA interstrand crosslink (ICL) repair resulting in chromosome breakage. The FA repair pathway comprises at least 22 FANC proteins including BRCA1 and BRCA2 and protects against carcinogenic endogenous and exogenous aldehydes. Individuals with FA are hundreds to thousands-fold more likely to develop head and neck (HNSCC), esophageal and anogenital squamous cell carcinomas (SCCs) with a median onset age of 31 years. The aggressive nature of these tumors and poor patient tolerance of platinum and radiation-based therapy have been associated with short survival in FA. Molecular studies of SCCs from individuals with FA (FA SCCs) have been limited, and it is unclear how they relate to sporadic HNSCCs primarily driven by tobacco and alcohol exposure or human papillomavirus (HPV) infection. Here, by sequencing FA SCCs, we demonstrate that the primary genomic signature of FA-deficiency is the presence of a high number of structural variants (SVs). SVs are enriched for small deletions, unbalanced translocations, and fold-back inversions that arise in the context of TP53 loss. The SV breakpoints preferentially localize to early replicating regions, common fragile sites, tandem repeats, and SINE elements. SVs are often connected forming complex rearrangements. Resultant genomic instability underlies elevated copy number alteration (CNA) rates of key HNSCC-associated genes, including PIK3CA, MYC, CSMD1, PTPRD, YAP1, MXD4, and EGFR. In contrast to sporadic HNSCC, we find no evidence of HPV infection in FA HNSCC, although positive cases were identified in gynecologic tumors. A murine allograft model of FA pathway-deficient SCC was enriched in SVs, exhibited dramatic tumor growth advantage, more rapid epithelial-to-mesenchymal transition, and enhanced autonomous inflammatory signaling when compared to an FA pathway-proficient model. In light of the protective role of the FA pathway against SV formation uncovered here, and recent findings of FA pathway insufficiency in the setting of increased formaldehyde load resulting in hematopoietic stem cell failure and carcinogenesis, we propose that high copy-number instability in sporadic HNSCC may result from functional overload of the FA pathway by endogenous and exogenous DNA crosslinking agents. Our work lays the foundation for improved FA patient treatment and demonstrates that FA SCC is a powerful model to study tumorigenesis resulting from DNA crosslinking damage. Citation Format: Andrew L. Webster, Mathijs A. Sanders, Krupa Patel, Ralf Dietrich, Raymond J. Noonan, Francis P. Lach, Ryan R. White, Audrey M. Goldfarb, Kevin Hadi, Matthew M. Edwards, Frank X. Donovan, Moonjung Jung, Sunandini Sridhar, Olivier Fedrigo, Huasong Tian, Joel Rosiene, Thomas Heineman, Jennifer Kennedy, Lorenzo Bean, Rasim O. Rosti, Rebecca Tryon, Ashlyn-Maree Gonzalez, Allana Rosenberg, Ji-Dung Luo, Thomas Carrol, Eunike Velleuer, Jeff C. Rastatter, Susanne I. Wells, Jordi Surrallés, Grover Bagby, Margaret L. MacMillan, John E. Wagner, Maria Cancio, Farid Boulad, Theresa Scognamiglio, Roger Vaughan, Amnon Koren, Marcin Imielinski, Settara Chandrasekharappa, Arleen D. Auerbach, Bhuvanesh Singh, David Kutler, Peter J. Campbell, Agata Smogorzewska. Fanconi anemia pathway deficiency drives copy number variation in squamous cell carcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 6196.

Abstract Immunotherapies mediate the regression of human tumors through the recognition of tumor antigens by immune cells, which triggers an immune response. Mutations in the RAS oncogene occur across various cancer histologies and are found in about 30% of all cancer patients. These mutations play an essential role in tumor establishment and survival and are most commonly found in hotspots - specifically at amino acid positions 12, 13, and 61. We have recently treated a patient who underwent a durable objective response after receiving tumor-infiltrating lymphocytes (TILs) that recognized a KRAS G12D mutation. T cell receptors (TCR) that recognize shared mutated RAS antigens presented on major histocompatibility complex (MHC) class I and class II molecules are thus promising reagents for “off-the-shelf” adoptive cell therapies (ACT) following insertion of the TCR into lymphocytes. We recently published a paper describing the discovery of anti-mutated RAS reactivities by using screening TIL and by performing in-vitro stimulation (IVS) of peripheral blood lymphocytes (PBLs). Interestingly by those two methods, we sometimes found reactivity or TCR in a patient in one method but not with the other method. In this work, we described the discovery of anti-mutated RAS TCRs by TIL IVS, which combines the best of the two described methods: using TILs coming from the tumor and therefore assumed to have a higher proportion of anti-tumor-reactive cells and stimulate them, which could enrich smaller populations. The specific anti-mutated RAS CD4 and CD8 TCRs were isolated by coculture of the reactive T cells with dendritic cells (DC) loaded with peptides or transfected with mRNA encoding RAS mutated antigens. The reactive T cells were subjected to single-cell sequencing to identify TCRs. The TCRs were reconstructed as a viral plasmid and retrovirally transduced into PBLs. The transduced TCRs were tested for avidity, MHC restriction, and specific recognition of the mutation. In the same patients tested by both methods, by TIL IVS, identified 12 anti-mutated RAS TCRs in addition the 9 TCRs that we could find by TIL screening. Overall, we present here the discovery of multiple mutation-specific anti-RAS TCRs and its MHC class I and class II restriction elements involved in tumor recognition. Each of the newly discovered TCRs recognized mutated RAS with high avidity and specificity and low to no reactivity against wild-type RAS. Testing of the TCR transduced cells to recognize tumor cell lines in-vitro and in-vivo demonstrated tumor cell line recognition. The anti-RAS mutated TCRs we discovered by all of our methods can potentially be used as an “off the shelf” treatment for the evaluation of TCR-based ACT in 45-60% of patients were tumor bears RAS mutations. Citation Format: Noam Levin, Frank J. Lowery, Maria R. Parkhurst, Zhiya Yu, Nolan R. Vale, Sanghyun P. Kim, Steven A. Rosenberg. Identification of T-cell receptors targeting RAS hotspot mutations using TIL IVS in human cancers for use in cell-based immunotherapy [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 3576.

BackgroundAlthough depression and mania are often assumed to be polar opposites, studies have shown that, in patients with bipolar disorder, they are weakly positively correlated and vary somewhat independently over time. Thus, when investigating relationships between specific psychological processes and specific symptoms (mania and depression), co-morbidity between the symptoms and changes over time must be taken into account.MethodA total of 253 bipolar disorder patients were assessed every 24 weeks for 18 months using the Hamilton Rating Scale for Depression (HAMD), the Bech–Rafaelsen Mania Assessment Scale (MAS), the Rosenberg Self-Esteem Questionnaire (RSEQ), the Dysfunctional Attitudes Scale (DAS), the Internal, Personal and Situational Attributions Questionnaire (IPSAQ) and the Personal Qualities Questionnaire (PQQ). We calculated multilevel models using the xtreg module of Stata 9.1, with psychological and clinical measures nested within each participant.ResultsMania and depression were weakly, yet significantly, associated; each was related to distinct psychological processes. Cross-sectionally, self-esteem showed the most robust associations with depression and mania: depression was associated with low positive and high negative self-esteem, and mania with high positive self-esteem. Depression was significantly associated with most of the other self-referential measures, whereas mania was weakly associated only with the externalizing bias of the IPSAQ and the achievement scale of the DAS. Prospectively, low self-esteem predicted future depression.ConclusionsThe associations between different self-referential thinking processes and different phases of bipolar disorder, and the presence of the negative self-concept in both depression and mania, have implications for therapeutic management, and also for future directions of research.

Introduction Self-stigmatization in patients with bipolar disorder could lead to shame, self-judgement, impaired quality of life, and could negatively affect self-esteem imeding recovery. Objectives The aim of this study was to assess self-stigma in remitted patients with bipolar disorder and to evaluate its impact on self-esteem. Methods We conducted a cross-sectional, descriptive, and analytical study of 61 patients with bipolar disorder. Euthymia was verified using the Hamilton scale for depression and the Young scale for mania. We used the Internalized Stigma of Mental Illness (ISMI) to evaluate self-stigma, and the Rosenberg scale to assess self-esteem. Results The mean age of patients was 43.4 years. The sex ratio was 2.4. The mean score on the ISMI was 2.36. More than half of our patients (59%) were self-stigmatized. With regard to self-esteem, the mean score obtained on the Rosenberg scale was 27.72. Low or very low self-esteem was found in 54% of patients. The most self-stigmatized patients had significantly lower self-esteem (p<10-3). Conclusions Internalized stigmatization negatively affects self-esteem of patients with bipolar disorder. Psychoeducation and cognitive behavioral therapy would improve self-esteem and enhance psychosocial treatment adherence and move people with bipolar disorder toward a culture of recovery based on hope and self-determination. Disclosure No significant relationships.

Os camarões encontram-se entre os representantes da ordem Decapoda (LATREILLE, 1802) e dentro dessa ordem está inserida a família Palaemonidae. O camarão Macrobrachium rosenbergii (De Man, 1879) é uma espécie de camarão de água doce, originária do sul e sudeste asiático, parte da Oceania e algumas ilhas do Oceano Pacífico, e considerado no Brasil uma espécie exótica. O estudo da biologia populacional das espécies na Amazônia Maranhense ajuda a compreender aspectos ecológicos da população, então avaliar a dinâmica populacional dos camarões e Macrobrachium rosenbergii na bacia do rio Pericumã. As coletas foram realizadas mensalmente, durante 12 meses do ano de 2020, em 3 pontos distintos ao longo do rio Pericumã, no período da noite, o sexo dos animais foi aferido e realizamos a retirada das medidas morfológicas. Foram 1.412 camarões da espécie M. rosenbergii, sendo 545 fêmeas, 548 machos e 319 juvenis. Os dados de L∞ obtidos a partir da curva de crescimento apresentaram variação de 12,10 a 15,03 cm para fêmeas, 10,08 a 13,14 cm para machos e 12,19 a 13,62 cm para sexos agrupados. O presente trabalho marca uma etapa importante para a Amazônia maranhense, pois irá subsidiar a exploração sustentável do animal desenvolvimento de pacotes tecnológicos para a carcinicultura continental.

The goal of the current study was to examine psychometric properties of the Serbian version of the Multidimensional Jealousy Scale (MJS, Pfeiffer & Wong, 1989). For this purpose, 500 participants, aged 18?40, were asked to complete this version of MJS. In order to examine external validity of MJS, participants were asked to complete The Rosenberg?s self-esteem scale, The Big Five Inventory and the Love Attitudes Scale. Confirmatory factor analysis supported the three-factor structure of the instrument, but required the addition of a number of error covariance arguments to achieve fit. Another model was tested, after which acceptable fit levels were achieved with smaller number of error covariance arguments in the model. Internal consistency of subscales was high. Correlations with neuroticism, self-esteem and mania love styles are consistent with the theoretical expectations and previous results, suggesting good external validity of the instrument.

The present study was conducted to determine the psychometric properties of the Polish version of The Love Attitudes Scale: Short Form (Hendrick et al., 1998). The scale is used to measure the love styles Eros, Ludus, Storge, Pragma, Mania, Agape based on John Lee's theory. The mean age of the subjects was 23 years (SD = 4.09). To determine the psychometric properties of the scale, an exploratory factor analysis, confirmatory factor analysis (RMSEA = 0.0425; CFI = 0.938; TLI = 0.928) was performed. The reliability of the Polish version of The Love Attitudes Scale: Short Form was measured using Cronbach's Alpha (0.67 for the total tool, for subscales 0.61 to 0.81) and McDonald's Omega (0.69 for the total tool, for subscales 0.66 to 0.82). An external validity analysis was also conducted using the Attachment Styles Questionnaire, the Sexual Satisfaction Questionnaire, Rosenberg self-esteem scale and the Well-being Questionnaire. Based on the results, the Polish version of The Love Attitudes Scale: Short Form can be considered a tool with good psychometric properties recommended for use in scientific research.

Human aggression is a major worldwide health issue that brings negative effects to victims, perpetrators, and society. One of the areas that may be potentially variables for understanding aggression is self-esteem that can influence whether someone will display aggressive behaviour. Therefore, the aim of this study was to determine the relationship between the level of aggression and level of self-esteem among Universiti Teknologi MARA (UiTM) Shah Alam student-athletes. This study is very important to determine the athlete’s aggression and self-esteem level based on the differences of genders and types of sport. Furthermore, the findings of this study may help in promoting a beneficial knowledge among coaches and athletes about aggression level and also self-esteem level toward maintaining and improving sports performance. A correlational study was selected in order to conduct this study. This correlational study was selected because this study was closely related to both descriptive and causal-comparative research. The instrument used for this study comprised of a 10-item Rosenberg SelfEsteem Scale (RSES) and 19-item of Aggression Questionnaire (AQ), which had been distributed in UiTM Shah Alam. The samples consisted of 260 UiTM Shah Alam athletes, included male and female, individual and team sports, age ranged between 18 until 26 years old. Independent t-test showed there was no significant difference between genders and types of sport on aggression level, p > 0.05. Result also showed that there was no significant difference on self-esteem between types of sport, p > 0.05. Meanwhile, a result found that there was a significant difference on self-esteem between genders, p < 0.05. Result also showed that there was a positive correlation between aggression and self-esteem among UiTM Shah Alam athletes, (r = 0.20, p < 0.05). Present findings indicated that athletes who had higher aggression level tend to have a higher level of self-esteem. Therefore, psychological skill training (PST) recommended as a better coping technique in order to promote better adaptation to the constraints of sports involvement.

A World Among these Islands: Essays on Literature, Race, and National Identity in Antillean America, by Roberto Márquez (reviewed by Peter Hulme) Caribbean Reasonings: The Thought of New World, The Quest for Decolonisation, edited by Brian Meeks & Norman Girvan (reviewed by Cary Fraser) Elusive Origins: The Enlightenment in the Modern Caribbean Historical Imagination, by Paul B. Miller (reviewed by Kerstin Oloff) Caribbean Perspectives on Modernity: Returning Medusa’s Gaze, by Maria Cristina Fumagalli (reviewed by Maureen Shay) Who Abolished Slavery: Slave Revolts and Abolitionism: A Debate with João Pedro Marques, edited by Seymour Drescher & Pieter C. Emmer, and Abolitionism and Imperialism in Britain, Africa, and the Atlantic, edited by Derek R . Peterson (reviewed by Claudius Fergus) The Mediterranean Apprenticeship of British Slavery, by Gustav Ungerer (reviewed by James Walvin) Children in Slavery through the Ages, edited by Gwyn Campbell, Suzanne Miers & Joseph C. Miller (reviewed by Indrani Chatterjee) The Invisible Hook: The Hidden Economics of Pirates, by Peter T. Leeson (reviewed by Kris Lane) Theorizing a Colonial Caribbean-Atlantic Imaginary: Sugar and Obeah, by Keith Sandiford (reviewed by Elaine Savory) Created in the West Indies: Caribbean Perspectives on V.S. Naipaul, edited by Jennifer Rahim & Barbara Lalla (reviewed by Supriya M. Nair) Thiefing Sugar: Eroticism between Women in Caribbean Literature, by Omise’eke Natasha Tinsley (reviewed by Lyndon K. Gill) Haiti Unbound: A Spiralist Challenge to the Postcolonial Canon, by Kaiama L. Glover (reviewed by Asselin Charles) Divergent Dictions: Contemporary Dominican Literature, by Néstor E. Rodríguez (reviewed by Dawn F. Stinchcomb) The Caribbean Short Story: Critical Perspectives, edited by Lucy Evans, Mark McWatt & Emma Smith (reviewed by Leah Rosenberg) Society of the Dead: Quita Manaquita and Palo Praise in Cuba, by Todd Ramón Ochoa (reviewed by Brian Brazeal) El Lector: A History of the Cigar Factory Reader, by Araceli Tinajero (reviewed by Juan José Baldrich) Blazing Cane: Sugar Communities, Class, and State Formation in Cuba, 1868-1959, by Gillian McGillivray (reviewed by Consuelo Naranjo Orovio) The Purposes of Paradise: U.S. Tourism and Empire in Cuba and Hawai’i, by Christine Skwiot (reviewed by Amalia L. Cabezas) A History of the Cuban Revolution, by Aviva Chomsky (reviewed by Michelle Chase) The Cubalogues: Beat Writers in Revolutionary Havana, by Todd F. Tietchen (reviewed by Stephen Fay) The Devil in the Details: Cuban Antislavery Narrative in the Postmodern Age, by Claudette M. Williams (reviewed by Gera Burton) Screening Cuba: Film Criticism as Political Performance during the Cold War, by Hector Amaya (reviewed by Ann Marie Stock) Perceptions of Cuba: Canadian and American Policies in Comparative Perspective, by Lana Wylie (reviewed by Julia Sagebien) Forging Diaspora: Afro-Cubans and African Americans in a World of Empire and Jim Crow, by Frank Andre Guridy (reviewed by Susan Greenbaum) The Irish in the Atlantic World, edited by David T. Gleeson (reviewed by Donald Harman Akenson) The Chinese in Latin America and the Caribbean, edited by Walton Look Lai & Tan Chee-Beng (reviewed by John Kuo Wei Tchen) The Island of One People: An Account of the History of the Jews of Jamaica, by Marilyn Delevante & Anthony Alberga (reviewed by Barry Stiefel) Creole Jews: Negotiating Community in Colonial Suriname, by Wieke Vink (reviewed by Aviva Ben-Ur) Only West Indians: Creole Nationalism in the British West Indies, by F.S.J. Ledgister (reviewed by Jerome Teelucksingh) Cultural DNA: Gender at the Root of Everyday Life in Rural Jamaica, by Diana J. Fox (reviewed by Jean Besson) Women in Grenadian History, 1783-1983, by Nicole Laurine Phillip (reviewed by Bernard Moitt) British-Controlled Trinidad and Venezuela: A History of Economic Interests and Subversions, 1830-1962, by Kelvin Singh (reviewed by Stephen G. Rabe) Export/Import Trends and Economic Development in Trinidad, 1919-1939, by Doddridge H.N. Alleyne (reviewed by Rita Pemberton) Post-Colonial Trinidad: An Ethnographic Journal, by Colin Clarke & Gillian Clarke (reviewed by Patricia van Leeuwaarde Moonsammy) Poverty in Haiti: Essays on Underdevelopment and Post Disaster Prospects, by Mats Lundahl (reviewed by Robert Fatton Jr.) From Douglass to Duvalier: U.S. African Americans, Haiti, and Pan Americanism, 1870-1964, by Millery Polyné (reviewed by Brenda Gayle Plummer) Haiti Rising: Haitian History, Culture and the Earthquake of 2010, edited by Martin Munro (reviewed by Jonna Knappenberger) Faith Makes Us Live: Surviving and Thriving in the Haitian Diaspora, by Margarita A. Mooney (reviewed by Rose-Marie Chierici) This Spot of Ground: Spiritual Baptists in Toronto, by Carol B. Duncan (reviewed by James Houk) Interroger les morts: Essai sur le dynamique politique des Noirs marrons ndjuka du Surinam et de la Guyane, by Jean-Yves Parris (reviewed by H.U.E. Thoden van Velzen & W. van Wetering)

Aydemir O, Akkaya C. Association of social anxiety with stigmatisation and low self-esteem in remitted bipolar patients.Background: In remitted bipolar disorder, it is aimed to show the association between social anxiety, self-esteem and stigmatisation.Methods: From two university clinics, a sample of 150 remitted bipolar patients was included in this study. Patients were assessed with Liebowitz Social Anxiety Scale, Rosenberg Self-Esteem Scale and sense of stigmatisation subscale of Bipolar Disorder Functioning Questionnaire (Stigma) and were rated with Hamilton Depression Rating Scale and Young Mania Rating Scale for mood symptoms. Confirmatory path analysis was performed.Results: The mean age of the patients was 39.5, and 52.7% (n = 79) were female. Ninety per cent (n = 135) of the patients had bipolar I disorder. The mean duration of the illness was 13.4 years and the mean number of episodes was 7.8. The model was subjected to confirmatory path analysis and the goodness-of-fit index was calculated to be 0.909, the confirmatory fit index was found to be 0.902 and the root mean square error of approximation was 0.097. Self-esteem was negatively associated with stigmatisation (r = −0.746). Social anxiety was positively associated with self-esteem (r = 0.494). Social anxiety was negatively associated with stigmatisation (r = −0.381).Conclusions: In remitted bipolar patients, social anxiety is very high and this social anxiety seems to be caused by self-stigmatisation and low self-esteem.

Com enorme pesar, registramos o falecimento em fevereiro passado do nosso editor associado, professor Tamás József Márton Károli Szmrecsányi. Ao longo de toda a existência da RBI, Tamás foi o mais ativo de todos os editores associados. Sempre disposto a colaborar, não só atendia prontamente os pedidos dos editores como espontaneamente encaminhava sugestões, especialmente para a seção Ideias Fundadoras. Em duas oportunidades colaborou diretamente nessa seção, indicando textos e elaborando sua apresentação aos leitores da revista. Na primeira indicou, em 2002, um texto menos conhecido de Joseph Schumpeter sobre teoria econômica e história empresarial, publicado em 1949, um ano antes da morte do autor. Na apresentação Tamás ressalta que nesse texto, “além de resumir e sistematizar suas contribuições anteriores sobre a função empresarial e o processo inovativo”, Schumpeter “abre-se para algumas novas perspectivas, raramente levadas em conta pelos divulgadores e seguidores de seu pensamento”, entre as quais “a inclusão do Estado no rol dos agentes da inovação tecnológica” (RBI, v.1, n.2, jul.-dez., 2002). Num estilo conciso, claro e objetivo, aliado a um tom irônico e provocativo, como era sua marca, Tamás nos legou nessa apresentação duas das melhores páginas publicadas na RBI. Na segunda colaboração (RBI, v.5, n.2, jul.-dez., 2006), ao apresentar um texto de Nathan Rosenberg, Tamás disseca a obra do autor e descreve sua trajetória nos campos de história econômica, história de empresas, história do pensamento econômico e história da ciência e da tecnologia. São páginas notáveis de erudição, capacidade de síntese e de percepção dos pontos de vista do autor. Sentiremos muito sua falta.

Abstract Background Current American Joint Committee on Cancer (AJCC) breast cancer staging considers contralateral axillary metastasis (CAM) stage IV disease (M1). Retrospective studies suggest that women with CAM have improved overall survival (OS) compared to those with distant metastasis (M1) and/or comparable OS to locally advanced breast cancer (LABC). These studies support consideration of curative intent treatment; however, they contain heterogeneous cohorts with highly variable treatment strategies. We sought to evaluate treatment and outcomes in a well-defined CAM cohort treated with contemporary systemic and locoregional therapy. Methods We performed a retrospective multi-institution cohort study to compare OS of patients with CAM matched 1:3 on age +/- 5 years to LABC (defined as cN2-3 and/or pN2-3), and to non-CAM M1. CAM patients classified as type 1) de novo CAM, synchronous with the contralateral primary, 2) metachronous isolated CAM in the setting of prior surgical and/or radiation treatment to primary index cancer, 3) synchronous with, or 4) metachronous after an in-breast or axillary nodal recurrence of the primary index cancer. The M1 cohort included de novo and recurrent metastasis with varied sites and number of metastasis. OS was defined as time from CAM diagnosis to death or last follow-up for CAM patients; time from primary diagnosis to death or last follow-up for LABC; and time from metastatic diagnosis to death or last follow-up for M1. Unadjusted OS was estimated with the Kaplan-Meier method, and Cox proportional hazards models were used to estimate the association of group with OS after adjustment for covariates Results We identified 57 CAM and 155 LABC from 8 institutions (2016-2022), and 632 M1 from a single institution. The median age was similar between groups (CAM=59 years, LABC=58, M1=57, p=0.44), and there were no statistically significant differences in hormone receptor status (p=0.25). There were more Non-Hispanic Black patients in the M1 cohort compared to CAM or LABC (p&lt; 0.001). The majority of CAM cases were delayed metachronous from the index cancer (type 2, 35.1%), or synchronous with a recurrence (type 3, 33.3%). Type 1 (de novo, 14%) and type 4 (delayed metachronous after breast cancer recurrence, 17.5%) were less frequent. Among CAM patients, 49.1% were hormone receptor positive (HR+)/HER2-negative (HER2-), 22.8% HR-/HER2-, 10.5% HR+/HER2+, and 5.3% HR-/HER2+. Comparing CAM versus LABC, invasive ductal carcinoma (IDC) was more commonly seen in CAM (82.5% vs 66.5%), as was grade 3 (45.6% vs 35.5%), and triple negative (22.8% vs 13.5%). Conversely, in LABC, treatment of the primary index cancer more frequently included chemotherapy (CAM=71.9%, LABC=92.3%), mastectomy (CAM=54.4%, LABC 74.2%), and adjuvant radiation (CAM=73.7%, LABC=90.3%). On multivariable analysis adjusting for age, race/ethnicity, and hormone receptor status, both CAM and M1 had inferior survival to LABC (Table 1), but with a 2.4-fold difference for CAM (95% CI 1.42-4.07, p=0.001) versus a 6.3-fold difference for M1 (95% CI 4.29-9.23, p=&lt; 0.001). Discussion In this contemporary, multi-institution study, we demonstrated that CAM patients selected for presumed curative intent treatment experienced improved OS when compared to stage IV (M1) patients. Our data adds additional support for re-evaluating the current stage IV designation, in favor of N3, and consideration of curative intent treatment in this disease. Table. Adjusted* Overall Survival Comparing Patients with Breast Cancer Contralateral Axillary Metastasis (CAM) to those with Locally Advanced Breast Cancer (LABC) and Metastatic Disease (M1) *Adjusted for age, race/ethnicity, hormone receptors. Citation Format: Meghan R. Flanagan, Stephanie Downs-Canner, Samantha Thomas, Astrid Botty van de bruele, Margaret Lillie, Kristalyn Gallagher, Tammeza Gibson, James Jakub, Alexandra Verosky, Sarah Tevis, Malia Brennan, Francys Verdial, Jennifer Q. Zhang, Leisha Elmore, Jennifer Plichta, Laura Rosenberger. A Multi-Institutional Review of Contralateral Axillary Metastases: Time for Reclassification as Local-Regional Event? [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO3-05-13.

Abstract Background: Data on the oncologic safety of omission of axillary lymph node dissection (ALND) in node positive (N+) patients who downstage to ypN0 with neoadjuvant chemotherapy (NAC) is sparse. Additionally, there is no consensus on which axillary staging procedure should be used in this setting, sentinel lymph node biopsy (SLNB) alone or in combination with localization and retrieval of the clipped positive node, also known as targeted axillary dissection (TAD). Whether the reduction in the false negative rate observed with TAD translates into a significant reduction in the rate of axillary recurrence is unknown. We sought to evaluate oncologic outcomes after omission of ALND in a large, real-world cohort of breast cancer (BC) patients and to compare rates of axillary recurrence after SLNB with dual tracer mapping vs. TAD. Methods: Data were collected from 19 centers in the Oncoplastic Breast Consortium (OPBC) and EUBREAST networks. Patients with T1-4 biopsy-proven N1-3 BC who underwent NAC followed by axillary staging with either SLNB with dual tracer mapping or TAD and who were pathologically node negative (ypN0) were included. ypN0 was defined as the absence of any tumor or isolated tumor cells. Competing risk analysis was performed to assess the cumulative incidence rates of axillary recurrence, locoregional recurrence, and any invasive (locoregional or distant) recurrence. Two-year cumulative incidence rates were compared between TAD and SLNB using the Gray’s test. Type I error rate was set to 0.05 (α). Results: We included 785 patients (565 treated with SLNB and 220 with TAD) treated with NAC followed by surgery from 01/2014-12/2020. Median patient age was 50 years. The majority (57%) of patients had clinical T2 tumors, and 95% had N1 disease. Most (55%) were HER2+, and 21% were triple negative. Most patients (81%) received anthracycline and taxane-based chemotherapy regimens, but NAC regimens differed between patients treated with TAD and those treated with SLNB (Table 1). All patients with HER2+ tumors received anti HER2 therapy. Nodal radiotherapy was administered to 76% of patients, and was more common in patients who underwent TAD (82% TAD vs 74% SLNB, p=0.017). Breast pathologic complete response (ypT0/is) was more frequent among those patients that had TAD (80% TAD vs. 66% SLNB, p&lt; 0.001). TAD localization was with wire in 46%, radioactive seed in 40%, ultrasound in 5%, tattoo in 2%, and with a combination of these techniques in 7%. The clipped node was successfully retrieved in 94% of TAD cases. The median number of lymph nodes removed was lower in the TAD group compared to the SLNB group [3 (IQR 3-5) vs 4 IQR 3-5), p&lt; 0.001], as was the median number of sentinel lymph nodes [3 (IQR 2-4) vs 4 IQR 3-5), p&lt; 0.001] (Table 1). The 5-year rates of any axillary recurrence, locoregional recurrence, and any invasive recurrence in the entire cohort were 1.1% (95%CI 0.39-2.4%), 3.1% (95%CI 1.6-5.3%) and 10% (95%CI 7.6-13%), respectively. The two-year cumulative incidence of axillary recurrence did not differ between patients treated with TAD compared to SLNB (0% vs 0.9%, p=0.19). Conclusion: Early axillary recurrence after omission of ALND in patients who successfully downstage from N+ to ypN0 with NAC is a rare event following both SLNB or TAD, and was not significantly lower in TAD than SLNB. Although longer follow-up is needed to confirm these findings, the main advantage of TAD seems to be a reduction in the number of lymph nodes removed. Overall, these results support omission of ALND in patients who successfully downstage to node negative disease after NAC. Table 1: Clinicopathological Features of the Study Cohort, Stratified by Axillary Staging Technique Citation Format: Giacomo Montagna, Mary Mrdutt, Astrid Botty, Andrea V. Barrio, Varadan Sevilimedu, Judy C. Boughey, Tanya L. Hoskin, Laura H. Rosenberger, E Shelley Hwang, Abigail Ingham, Bärbel Papassotiropoulos, Bich Doan Nguyen-Sträuli, Christian Kurzeder, Danilo Diaz Aybar, Denise Vorburger, Dieter Michael Matlac, Edvin Ostapenko, Fabian Riedel, Florian Fitzal, Francesco Meani, Franziska Fick, Jacqueline Sagasser, Jörg Heil, Konstantin J. Dedes, Laszlo Romics, Maggie Banys-Paluchowski, Maria Del Rosario Cueva Perez, Marcelo Chavez Diaz, Martin Heidinger, Mathias K. Fehr, Mattea Reinisch, Nadia Maggi, Nicola Rocco, Nina Ditsch, Oreste Davide Gentilini, Regis Resende Paulinelli, Sebastian Sole Zarhi, Sherko Küemmel, Simona Bruzas, Simona Di Lascio, Tamara Parissenti, Uwe Güth, Valentina Ovalle, Christoph Tausch, Monica Morrow, Thorsten Kühn, Walter P. Weber. Oncological Outcomes Following Omission of Axillary Lymph Node Dissection in Node Positive Patients Downstaging To Node Negative with Neoadjuvant Chemotherapy: the OPBC-04/EUBREAST-06/OMA study [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr GS4-02.

AbstractBackgroundTaking selfies is spreading like a mania across the globe. It may positively or negatively affect the self-esteem of an individual.ObjectiveThe present study was undertaken to assess the proportion of medical undergraduates and teaching faculty involved in taking selfies, to compare the pattern of selfie taking among medical undergraduates and teaching faculty and to assess the self-esteem score among them.SubjectsThe subject consisted of medical undergraduates and teaching faculty of Kasturba Medical College, Mangalore.MethodsA cross-sectional study was carried out. A semi-structured questionnaire was prepared. Self-esteem was assessed by using the Rosenberg Self-esteem Scale. Information obtained was analyzed using SPSS 11.5.ResultsThe study included 366 participants of the study population. The Rosenberg Self-esteem Scale conclude that 96% of the faculty and 84% of the students have normal self-esteem. Around 52.73% of them agree that they find selfie taking can be addictive, 43.72% of them agree that selfie taking can have disastrous effects, sometimes even life threatening and 57.92% of them agree that they enjoy the habit of selfie taking and find entertainment in it.ConclusionIt was found that most undergraduates and teaching faculty indulge in the act of selfie taking. Students tend to take selfies to share their current lifestyle, whereas faculty take selfies for convenience. It is found that selfies does not affect the self-esteem of an individual as the majority of the population were found to have normal self-esteem.

Aims: To identify the species of decapods and their edibility, determine the population density, abundance, dominance, and diversity indices of decapods found in the selected mangrove sites, and measure the physicochemical parameters of the area. Place and Duration of Study: Barangay Tanglad, Mamacao, and Basiawan of the Municipality of Sta. Maria, Davao Occidental. April 25-29, 2022. Methodology: A transect-plot method was used in sampling and the samples were handpicked or captured using tongs, scooped using the locally used net, dug from their burrows, and collected from wooden hides. The samples were put in a container with seawater and ice, then cleaned, photographed, and identified. The samples were presented to the fisherfolks and locals to identify local names and their edibility. The pH, temperature, and salinity of the seawater were recorded on site. The decapods’ taxonomic classification was identified. The population density, abundance, dominance, and diversity indices were computed. Results: There were 13 species of decapods found in the three sampling sites, namely: Triangular fiddler crab (A. triangularis), Nymph snapping shrimp (A. euphrosyne), Mud crab (B. vinosus), Forceps crab (E. dentatus), Brown land crab (C. carnifex), Hermit crab (C. rugosus), Indian prawn (F. indicus), Giant freshwater prawn (M. rosenbergii), Alamihi crab (M. thukuhar), Mudflat crab (P. pictum), Flat porcelain crab (P. cinctipes), Mangrove swimming crab (T. crenata), and Compressed fiddler crab (T. coarctata). A total of 633 individuals were gathered from the three sampling sites. 279 individuals were collected in Barangay Tanglad, 189 individuals in Barangay Mamacao, and 165 individuals in Barangay Basiawan. Triangular fiddler crab (A. triangularis), Hermit crab (C. rugosus), Indian prawn (F. indicus), Alamihi crab (M. thukuhar), Mudflat Crab (P. pictum), and Compressed fiddler crab (T. coarctata) were observed to be present among the three sites. In the three sampling sites, Mudflat crab (P. pictum) showed to have the highest population density of 199 ind./2,700 m2, highest index of the dominance of 0.291, and a relative abundance of 31.44%. Mudflat crab (P. pictum), Triangular fiddler crab (A. triangularis), and Compressed fiddler crab (T. coarctata) were the most dominant species in the area. Conclusion: Barangay Tanglad was found to be the most diverse site, it also had the highest index of evenness. Barangay Mamacao and Basiawan had the highest similarity index. There was no significant difference in the number of decapod species between the sampling sites. The physicochemical parameters are within the optimum level which could be a favorable condition for the abundance of the decapods.

Alex Abou-Chebl, MD Michael Abraham, MD Joseph E. Acker, III, EMT-P, MPH Robert Adams, MD, MS, FAHA Eric Adelman, MD Opeolu Adeoye, MD DeAnna L. Adkins, PhD Maria Aguilar, MD Absar Ahmed, MD Naveed Akhtar, MD Rufus Akinyemi, MBBS, MSc, MWACP, FMCP(Nig) Karen C. Albright, DO, MPH Felipe Albuquerque, MD Andrei V. Alexandrov, MD Abdulnasser Alhajeri, MD Latisha Ali, MD Nabil J. Alkayed, MD, PhD, FAHA Amer Alshekhlee, MD, MSc Irfan Altafullah, MD Arun Paul Amar, MD Pierre Amarenco, MD, FAHA, FAAN Sepideh Amin-Hanjani, MD, FAANS, FACS, FAHA Catherine Amlie-Lefond, MD Aaron M. Anderson, MD David C. Anderson, MD, FAHA Sameer A. Ansari, MD, PhD Ken Arai, PhD Agnieszka Ardelt, MD, PhD Juan Arenillas, MD PhD William Armstead, PhD, FAHA Jennifer L. Armstrong-Wells, MD, MPH Negar Asdaghi, MD, MSc, FRCPC Nancy D. Ashley, APRN,BC, CEN,CCRN,CNRN Stephen Ashwal, MD Andrew Asimos, MD Rand Askalan, MD, PhD Kjell Asplund, MD Richard P. Atkinson, MD, FAHA Issam A. Awad, MD, MSc, FACS, MA (hon) Hakan Ay, MD, FAHA Michael Ayad, MD, PhD Cenk Ayata, MD Aamir Badruddin, MD Hee Joon Bae, MD, PhD Mark Bain, MD Tamilyn Bakas, PhD, RN, FAHA, FAAN Frank Barone, BA, DPhil Andrew Barreto, MD William G. Barsan, MD, FACEP, FAHA Nicolas G. Bazan, MD, PhD Kyra Becker, MD, FAHA Ludmila Belayev, MD Rodney Bell, MD Andrei B. Belousov, PhD Susan L. Benedict, MD Larry Benowitz, PhD Rohit Bhatia, MBBS, MD, DM, DNB Pratik Bhattacharya, MD MPh James A. Bibb, PhD Jose Biller, MD, FACP, FAAN, FAHA Randie Black Schaffer, MD, MA Kristine Blackham, MD Bernadette Boden-Albala, DrPH Cesar Borlongan, MA, PhD Susana M. Bowling, MD Monique M. B. Breteler, MD, PhD Jonathan Brisman, MD Allan L. Brook, MD, FSIR Robert D. Brown, MD, MPH Devin L. Brown, MD, MS Ketan R. Bulsara, MD James Burke, MD Cheryl Bushnell, MD, MHSc, FAHA Ken Butcher, MD, PhD, FRCPC Livia Candelise, MD S Thomas Carmichael, MD, PhD Bob S. Carter, MD, PhD Angel Chamorro, MD, PhD Pak H. Chan, PhD, FAHA Seemant Chaturvedi, MD, FAHA, FAAN Peng Roc Chen, MD Jun Chen, MD Eric Cheng, MD, MS Huimahn Alex Choi, MD Sherry Chou, MD, MMSc Michael Chow, MD, FRCS(C), MPH Marilyn Cipolla, PhD, MS, FAHA Kevin Cockroft, MD, MSc, FACS Domingos Coiteiro, MD Alexander Coon, MD Robert Cooney, MD Shelagh B. Coutts, BSc, MB.ChB., MD, FRCPC, FRCP(Glasg.) Elizabeth Crago, RN, MSN Steven C. Cramer, MD Carolyn Cronin, MD, PhD Dewitte T. Cross, MD Salvador Cruz-Flores, MD, FAHA Brett L. Cucchiara, MD, FAHA Guilherme Dabus, MD M Ziad Darkhabani, MD Stephen M. Davis, MD, FRCP, Edin FRACP, FAHA Deidre De Silva, MBBS, MRCP Amir R. Dehdashti, MD Gregory J. del Zoppo, MD, MS, FAHA Bart M. Demaerschalk, MD, MSc, FRCPC Andrew M. Demchuk, MD Andrew J. DeNardo, MD Laurent Derex, MD, PhD Gabrielle deVeber, MD Helen Dewey, MB, BS, PhD, FRACP, FAFRM(RACP) Mandip Dhamoon, MD, MPH Orlando Diaz, MD Martin Dichgans, MD Rick M. Dijkhuizen, PhD Michael Diringer, MD Jodi Dodds, MD Eamon Dolan, MD, MRCPI Amish Doshi, MD Dariush Dowlatshahi, MD, PhD, FRCPC Alexander Dressel, MD Carole Dufouil, MD Dylan Edwards, PhD Mitchell Elkind, MD, MS, FAAN Matthias Endres, MD Joey English, MD, PhD Conrado J. Estol, MD, PhD Mustapha Ezzeddine, MD, FAHA Susan C. Fagan, PharmD, FAHA Pierre B. Fayad, MD, FAHA Wende Fedder, RN, MBA, FAHA Valery Feigin, MD, PhD Johanna Fifi, MD Jessica Filosa, PhD David Fiorella, MD, PhD Urs Fischer, MD, MSc Matthew L. Flaherty, MD Christian Foerch, MD Gregg C. Fonarow, MD, FAHA Andria Ford, MD Christine Fox, MD, MAS Isabel Fragata, MD Justin Fraser, MD Don Frei, MD Gary H. Friday, MD, MPH, FAAN, FAHA Neil Friedman, MBChB Michael Froehler, MD, PhD Chirag D. Gandhi, MD Hannah Gardener, ScD Madeline Geraghty, MD Daniel P. Gibson, MD Glen Gillen, EdD, OTR James Kyle Goddard, III, MD Daniel A. Godoy, MD, FCCM Joshua Goldstein, MD, PhD, FAHA Nicole R. Gonzales, MD Hector Gonzalez, PhD Marlis Gonzalez-Fernandez, MD, PhD Philip B. Gorelick, MD, MPH, FAHA Matthew Gounis, PhD Prasanthi Govindarajan, MD Manu Goyal, MD, MSc Glenn D. Graham, MD, PhD Armin J. Grau, MD, PhD Joel Greenberg, PhD, FAHA Steven M. Greenberg, MD, PhD, FAHA David M. Greer, MD, MA, FCCM James C. Grotta, MD, FAHA Jaime Grutzendler, MD Rishi Gupta, MD Andrew Gyorke, MD Mary N. Haan, MPH, DrPH Roman Haberl, MD Maree Hackett, PhD Elliot Clark Haley, MD, FAHA Hen Hallevi, MD Edith Hamel, PhD Graeme J. Hankey, MBBS, MD, FRCP, FRCP, FRACP Amer Haque, MD Richard L. Harvey, MD Don Heck, MD Cathy M. Helgason, MD Thomas Hemmen, MD, PhD Dirk M. Hermann, MD Marta Hernandez, MD Paco Herson, PhD Michael D. Hill, MD, MSc, FRCPC Nancy K. Hills, PhD, MBA Robin C. Hilsabeck, PhD, ABPP-CN Judith A. Hinchey, MD, MS, FAHA Robert G. Holloway, MD, MPH William Holloway, MD Sherril K. Hopper, RN Jonathan Hosey, MD, FAAN George Howard, DPH, FAHA Virginia J. Howard, PhD, FAHA David Huang, MD, PhD Daniel Huddle, DO Richard L. Hughes, MD, FAHA, FAAN Lynn Hundley, RN, MSN, ARNP, CCRN, CNRN, CCNS Patricia D. Hurn, PhD, FAHA Muhammad Shazam Hussain, MD, FRCPC Costantino Iadecola, MD Rebecca N. Ichord, MD M. Arfan Ikram, MD Kachi Illoh, MD Pascal Jabbour, MD Bharathi D. Jagadeesan, MD Vivek Jain, MD Dara G. Jamieson, MD, FAHA Brian T. Jankowitz, MD Edward C. Jauch, MD, MS, FAHA, FACEP David Jeck, MD Sayona John, MD Karen C. Johnston, MD, FAHA S Claiborne Johnston, MD, FAHA Jukka Jolkkonen, PhD Stephen C. Jones, PhD, SM, BSc Theresa Jones, PhD Anne Joutel, MD, PhD Tudor G. Jovin, MD Mouhammed R. Kabbani, MD Yasha Kadkhodayan, MD Mary A. Kalafut, MD, FAHA Amit Kansara, MD Moira Kapral, MD, MS Navaz P. Karanjia, MD Wendy Kartje, MD, PhD Carlos S. Kase, MD, FAHA Scott E. Kasner, MD, MS, FAHA Markku Kaste, MD, PhD, FESO, FAHA Prasad Katakam, MD, PhD Zvonimir S. Katusic, MD Irene Katzan, MD, MS, FAHA James E. Kelly, MD Michael Kelly, MD, PhD, FRCSC Peter J. Kelly, MD, MS, FRCPI, ABPN (Dip) Margaret Kelly-Hayes, EdD, RN, FAAN David M. Kent, MD Thomas A. Kent, MD Walter Kernan, MD Salomeh Keyhani, MD, MPH Alexander Khalessi, MD, MS Nadia Khan, MD, FRCPC, MSc Naim Naji Khoury, MD, MS Chelsea Kidwell, MD, FAHA Anthony Kim, MD Howard S. Kirshner, MD, FAHA Adam Kirton, MD, MSc, FRCPC Brett M. Kissela, MD Takanari Kitazono, MD, PhD Steven Kittner, MD, MPH Jeffrey Kleim, PhD Dawn Kleindorfer, MD, FAHA N. Jennifer Klinedinst, PhD, MPH, MSN, RN William Knight, MD Adam Kobayashi, MD, PhD Sebastian Koch, MD Raymond C. Koehler, PhD, FAHA Ines P. Koerner, MD, PhD Martin Köhrmann, MD Anneli Kolk, PhD, MD John B. Kostis, MD Tobias Kurth, MD, ScD Peter Kvamme, MD Eduardo Labat, MD, DABR Daniel T. Lackland, BA, DPH, FAHA Kamakshi Lakshminarayan, MD, PhD Joseph C. LaManna, PhD Catherine E. Lang, PT, PhD Maarten G. Lansberg, MD, PhD, MS Giuseppe Lanzino, MD Paul A. Lapchak, PhD, FAHA Sean Lavine, MD Ronald M. Lazar, PhD Marc Lazzaro, MD Jin-Moo Lee, MD, PhD Meng Lee, MD Ting-Yim Lee, PhD Erica Leifheit-Limson, PhD Enrique Leira, MD, FAHA Deborah Levine, MD, MPh Joshua M. Levine, MD Steven R. Levine, MD Christopher Lewandowski, MD Daniel J. Licht, MD Judith H. Lichtman, PhD, MPH David S. Liebeskind, MD, FAHA Shao-Pow Lin, MD, PhD Weili Lin, PhD Ute Lindauer, PhD Italo Linfante, MD Lynda Lisabeth, PhD, FAHA Alice Liskay, RN, BSN, MPA, CCRC Warren Lo, MD W. T. Longstreth, MD, MPH, FAHA George A. Lopez, MD, PhD David Loy, MD, PhD Andreas R. Luft, MD Helmi Lutsep, MD, FAHA William Mack, MD Mark MacKay, MBBS, FRACP Jennifer Juhl Majersik, MD Marc D. Malkoff, MD, FAHA Randolph S. Marshall, MD John H. Martin, PhD Alexander Mason, MD Masayasu Matsumoto, MD, PhD Elizabeth Mayeda, MPH William G. Mayhan, PhD Avi Mazumdar, MD Louise D. McCullough, MD, PhD Erin McDonough, MD Lisa Merck, MD, MPH James F. Meschia, MD, FAHA Steven R. Messe, MD Joseph Mettenburg, MD,PhD William Meurer, MD BA Brett C. Meyer, MD Robert Mikulik, MD, PhD James M. Milburn, MD Kazuo Minematsu, MD, PhD J Mocco, MD, MS Yousef Mohammad, MD MSc FAAN Mahendranath Moharir, MD, MSc, FRACP Carlos A. Molina, MD Joan Montaner, MD PhD Majaz Moonis, MD, MRCP Christopher J. Moran, MD Henry Moyle, MD, PhD Susanne Muehlschlegel, MD, MPH Susanne Muehlschlegel, MD, MPH Yuichi Murayama, MD Stephanie J. Murphy, VMD, PhD, DACLAM, FAHA Fadi Nahab, MD Andrew M. Naidech, MD, MPh Ashish Nanda, MD Sandra Narayanan, MD William Neil, MD Edwin Nemoto, PhD, FAHA Lauren M. Nentwich, MD Perry P. Ng, MD Al C. Ngai, PhD Andrew D. Nguyen, MD, PhD Thanh Nguyen, MD, FRCPC Mai Nguyen-Huynh, MD, MAS Raul G. Nogueira, MD Bo Norrving, MD Robin Novakovic, MD Thaddeus Nowak, PhD David Nyenhuis, PhD Michelle C. Odden, PhD Michael O'Dell, MD Christopher S. Ogilvy, MD Jamary Oliveira-Filho, MD, PhD Jean Marc Olivot, MD, PhD Brian O'Neil, MD, FACEP Bruce Ovbiagele, MD, MSc, FAHA Shahram Oveisgharan, MD Mayowa Owolabi, MBBS,MWACP,FMCP Aditya S. Pandey, MD Dhruvil J. Pandya, MD Nancy D. Papesh, BSN, RN, CFRN, EMT-B Helena Parfenova, PhD Min S. Park, MD Matthew S. Parsons, MD Aman B. Patel, MD Srinivas Peddi, MD Joanne Penko, MS, MPH Miguel A. Perez-Pinzon, PhD, FAHA Paola Pergami, MD, PhD Michael Phipps, MD Anna M. Planas, PhD Octavio Pontes-Neto, MD Shyam Prabhakaran, MD, MS Kameshwar Prasad, MD, DM, MMSc, FRCP, FAMS Charles Prestigiacomo, MD, FAANS, FACS G. Lee Pride, MD Janet Prvu Bettger, ScD, FAHA Volker Puetz, MD, PhD Svetlana Pundik, MD Terence Quinn, MD, MRCP, MBChb (hons), BSc (hons) Alejandro Rabinstein, MD Mubeen Rafay, MB.BS, FCPS, MSc Preeti Raghavan, MD Venkatakrishna Rajajee, MD Kumar Rajamani, MD Peter A. Rasmussen, MD Kumar Reddy, MD Michael J. Reding, MD Bruce R. Reed, PhD Mathew J. Reeves, BVSc, PhD, FAHA Martin Reis, MD Marc Ribo, MD, PhD David Rodriguez-Luna, MD, PhD Charles Romero, MD Jonathan Rosand, MD Gary A. Rosenberg, MD Michael Ross, MD, FACEP Natalia S. Rost, MD, MA Elliot J. Roth, MD, FAHA Christianne L. Roumie, MD, MPH Marilyn M. Rymer, MD, FAHA Ralph L. Sacco, MS, MD, FAAN, FAHA Edgar A. Samaniego, MD, MS Navdeep Sangha, BS, MD Nerses Sanossian, MD Lauren Sansing, MD, MSTR Gustavo Saposnik, MD, MSc, FAHA Eric Sauvageau, MD Jeffrey L. Saver, MD, FAHA, FAAN Sean I. Savitz, MD, FAHA Judith D. Schaechter, PhD Lee H. Schwamm, MD, FAHA Phillip Scott, MD, FAHA Magdy Selim, MD, PhD, FAHA Warren R. Selman, MD, FAHA Souvik Sen, MD, MS, MPH, FAHA Frank Sharp, MD, FAHA, FAAN George Shaw, MD, PhD Kevin N. Sheth, MD Vilaas Shetty, MD Joshua Shimony, MD, PhD Yukito Shinohara, MD, PhD Ashfaq Shuaib, MD, FAHA Lori A. Shutter, MD Cathy A. Sila, MD, FAAN Gisele S. Silva, MD Brian Silver, MD Daniel E. Singer, MD Robert Singer, MD Aneesh B. Singhal, MD Lesli Skolarus, MD Eric E. Smith, MD Sabrina E. Smith, MD, PhD Christopher Sobey, PhD, FAHA J David Spence, MD Christian Stapf, MD Joel Stein, MD Michael F. Stiefel, MD, PhD Sophia Sundararajan, MD, PhD David Tanne, MD Robert W. Tarr, MD Turgut Tatlisumak, MD, PhD, FAHA, FESO Charles H. Tegeler, MD Mohamed S. Teleb, MD Fernando Testai, MD, PhD Ajith Thomas, MD Stephen Thomas, MD, MPH Bradford B. Thompson, MD Amanda Thrift, PhD, PGDipBiostat David Tong, MD Michel Torbey, MD, MPH, FCCM, FAHA Emmanuel Touze, MD, PhD Amytis Towfighi, MD Richard J. Traystman, PhD, FAHA Margaret F. Tremwel, MD, PhD, FAHA Brian Trimble, MD Georgios Tsivgoulis, MD Tanya Turan, MD, FAHA Aquilla S. Turk, DO Michael Tymianski, MD, PhD, FRCSC Philippa Tyrrell, MB, MD, FRCP Shinichiro Uchiyama, MD, FAHA Luis Vaca, MD Renee Van Stavern, MD Susan J. Vannucci, PhD Dale Vaslow, MD, PHD Zena Vexler, PhD Barbara Vickrey, MD, MPH Ryan Viets, MD Anand Viswanathan, MD, PhD Salina Waddy, MD Kenneth R. Wagner, PhD Lawrence R. 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