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Livros sobre o tema "Lymphocytes T régulateurs – Cancer"

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1

L, Kripke Margaret, Frost Philip 1940- e M.D. Anderson Hospital and Tumor Institute., eds. Immunology and cancer. Austin: Published for the University of Texas System Cancer Center, M.D. Anderson Hospital and Tumor Institute, Houston, Tex. by the University of Texas Press, 1986.

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2

Alexander, Michael A. Immune-based cancer treatment: The T lymphocyte response. Boca Raton, FL: CRC Press, 2011.

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3

Alexander, Michael A. Immune-based cancer treatment: The T lymphocyte response. Boca Raton, FL: CRC Press, 2011.

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4

Clark, Lambert W., Giannotti B, Vloten W. A. van, North Atlantic Treaty Organization. Scientific Affairs Division. e NATO Advanced Research Workshop on Basic Mechanisms of Physiologic and Aberrant Lymphoproliferation in the Skin (1991 : San Miniato, Italy), eds. Basic mechanisms of physiologic and aberrant lymphoproliferation in the skin. New York: Plenum Press, 1994.

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5

Symposium, Takamatsu no Miya Hi Gan Kenkyū Kikin International. Retroviruses in human lymphoma/leukemia: Proceedings of the 15th International Symposium of the Princess Takamatsu Cancer Research Fund, Tokyo, 1984. Tokyo: Japan Scientific Societies Press, 1985.

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6

1944-, Finke James H., e Bukowski Ronald M, eds. Cancer immunotherapy at the crossroads: How tumors evade immunity and what can be done. Totowa, N.J: Humana Press, 2004.

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7

1944-, Finke James H., e Bukowski Ronald M, eds. Cancer immunotherapy at the crossroads: How tumors evade immunity and what can be done. Totowa, N.J: Humana Press, 2004.

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8

Burkhard, Ludewig, e Hoffmann Matthias W, eds. Adoptive immunotherapy: Methods and protocols. Totowa, N.J: Humana Press, 2005.

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9

Immunotherapy of cancer with sensitized T lymphocytes. Austin: R.G. Landes, 1994.

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10

Medin, Jeffrey, e Daniel Fowler. Experimental and Applied Immunotherapy. Springer, 2011.

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11

Medin, Jeffrey, e Daniel Fowler. Experimental and Applied Immunotherapy. Humana, 2014.

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12

Cellular Therapy Of Cancer. World Scientific Publishing Company, 2010.

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13

(Editor), James H. Finke, e Ronald M. Bukowski (Editor), eds. Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done (Current Clinical Oncology). Humana Press, 2003.

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14

McMichael, A. J. A New Look at Tumour Immunology (Cancer Surveys Series Vol 13) (Cancer Surveys Series Vol 13). Cold Spring Harbor Laboratory Pr, 1992.

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15

(Editor), K. Kikuchi, B. J. Van Den Eynde (Editor) e N. Sato (Editor), eds. Recent Advances of Human Tumor Immunology and Immunotherapy (Gann Monograph on Cancer Research). Not Avail, 1999.

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16

Hawkins, Robert E. Cellular Therapy of Cancer: Development of Gene Therapy Based Approaches. World Scientific Publishing Co Pte Ltd, 2014.

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17

Ludewig, Burkhard, e Matthias W. Hoffmann. Adoptive Immunotherapy: Methods and Protocols. Humana Press, 2010.

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18

Adoptive immunotherapy: Methods and protocols. Totowa, NJ: Humana Press, 2004.

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19

Moerdler, Scott, e Xingxing Zang. PD-1/PDL-1 Inhibitors as Immunotherapy for Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0010.

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Resumo:
Programmed death 1 (PD-1), a member of the B7-CD28 immunoglobulin superfamily, and its ligands PD-L1/PD-L2 inhibit T-cell activation. They also play a key role in the tumor microenvironment, allowing for cancer immune escape. PD-1 is induced on a variety of immune cells, including tumor-infiltrating lymphocytes (TILs), while PD-L1 is found on many types of solid tumors including ovarian cancer and some TILs. The use of immunocheckpoint inhibitors like anti-PD-1 and anti-PD-L1 therapies has been shown to reactivate the immune system to attack tumor cells. Ovarian cancers have been shown to be responsive to anti-PD-1 and anti-PD-L1 therapies, though immunocheckpoint inhibitors are not enough. Current research is evaluating combination therapies to improve response rates.
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