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1

Sanderson, Victoria P., Jennifer C. Miller, Vladimir V. Bamm, et al. "Profiling disease burden and Borrelia seroprevalence in Canadians with complex and chronic illness." PLOS ONE 18, no. 11 (2023): e0291382. http://dx.doi.org/10.1371/journal.pone.0291382.

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Lyme disease, caused by vector-borne Borrelia bacteria, can present with diverse multi-system symptoms that resemble other conditions. The objective of this study was to evaluate disease presentations and Borrelia seroreactivity in individuals experiencing a spectrum of chronic and complex illnesses. We recruited 157 participants from Eastern Canada who reported one or more diagnoses of Lyme disease, neurological, rheumatic, autoimmune, inflammatory, gastrointestinal, or cardiovascular illnesses, or were asymptomatic and presumed healthy. Intake categories were used to classify participants ba
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Coiffier, Guillaume, and Pierre Tattevin. "Lyme disease: “End of the debate?”." Joint Bone Spine 88, no. 4 (2021): 105181. http://dx.doi.org/10.1016/j.jbspin.2021.105181.

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Yarema, Nadiya, Kateryna Myndziv, and Volodymyr Dzhyvak. "Lyme carditis in clinical practice." Acta Facultatis Medicae Naissensis 41, no. 1 (2024): 139–45. http://dx.doi.org/10.5937/afmnai41-39831.

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Introduction. Lyme disease is an infectious disease transmitted by the Ixodes ticks and is manifested by damaging various organs and systems (most often-migrating erythema, damage to the nervous system, musculoskeletal system, heart, liver and eyes). According to various authors, heart damage in Lyme borreliosis ranges from 4% to 10% and is an understudied pathology. Case report. The article describes a clinical case of infectious myocarditis associated with Lyme disease in a 51-year-old patient. The course of the disease and the results of treatment of the patient were analyzed. The severe rh
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4

Kennel, Peter J., Melvin Parasram, Daniel Lu, et al. "A Case of Lyme Carditis Presenting with Atrial Fibrillation." Case Reports in Cardiology 2018 (September 2, 2018): 1–5. http://dx.doi.org/10.1155/2018/5265298.

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We report a case of a 20-year-old man who presented to our institution with a new arrhythmia on a routine EKG. Serial EKG tracings revealed various abnormal rhythms such as episodes of atrial fibrillation, profound first degree AV block, and type I second degree AV block. He was found to have positive serologies for Borrelia burgdorferi. After initiation of antibiotic therapy, the atrial arrhythmias and AV block resolved. Here, we present a case of Lyme carditis presenting with atrial fibrillation, a highly unusual presentation of Lyme carditis.
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Shabbir, Muhammad Asim, Muhammad Hamza Saad Shaukat, Muhammad Hashaam Arshad, and Joseph Sacco. "Lyme carditis presenting as atrial fibrillation in a healthy young male." BMJ Case Reports 12, no. 6 (2019): e229261. http://dx.doi.org/10.1136/bcr-2019-229261.

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We present a case of a 23-year-old man coming with palpitations, found to be in atrial fibrillation (AF). He was initially managed with metoprolol for rate-controlled therapy—reverted to normal sinus rhythm and discharged home. He returned a few days later—this time in varying degrees of atrioventricular block including transient complete heart block. He was empirically started on intravenous ceftriaxone for suspected Lyme carditis, which subsequently led to the resolution of high-degree heart block. Lyme immunoglobulin G (IgG) and IgM returned positive. Follow-up ECG after the course of antib
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6

Muhammad, Sheheryar, and Robert J. Simonelli. "Lyme Carditis: A Case Report and Review of Management." Hospital Pharmacy 53, no. 4 (2018): 263–65. http://dx.doi.org/10.1177/0018578717749927.

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Purpose: A case report of a patient who presented with an acute onset, fluctuating atrioventricular (AV) block and was diagnosed with Lyme carditis is presented. Summary: A 55-year-old man with progressively worsening generalized malaise, flu-like symptoms, dyspnea on exertion, and near syncope was admitted with bradycardia (heart rate was between 20 and 30 beats per minute upon admission). He endorsed having several tick bites after which he developed erythema migrans on his arm and abdomen. An electrocardiogram (ECG) revealed a second-degree AV block, fluctuating between Mobitz type I and Mo
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7

Dersch, R., M. H. Freitag, S. Schmidt, H. Sommer, S. Rauer, and J. J. Meerpohl. "Efficacy and safety of pharmacological treatments for acute Lyme neuroborreliosis - a systematic review." European Journal of Neurology 22, no. 9 (2015): 1249–59. http://dx.doi.org/10.1111/ene.12744.

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8

Marx, Grace E., Anna M. Schotthoefer, Brian S. Schwartz, et al. "1198. Lyme Disease Post-Exposure Prophylaxis by Single-Dose Doxycycline in Three Healthcare Systems." Open Forum Infectious Diseases 8, Supplement_1 (2021): S690. http://dx.doi.org/10.1093/ofid/ofab466.1390.

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Abstract Background Lyme disease, the most common tickborne disease in the United States, may be prevented by taking a single 200-mg dose of oral doxycycline after a high-risk bite from a blacklegged tick. Currently, it is not known how Lyme disease post-exposure prophylaxis (PEP) might vary by region and healthcare system. We identified single-dose doxycycline medication orders in three healthcare systems in states with high incidence of Lyme disease and compared associated patient and provider characteristics. Methods Electronic health record data during 2012 – 2016 were obtained from three
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9

Michalski, Basia, and Adrian Umpierrez De Reguero. "Lyme Carditis Buried Beneath ST-Segment Elevations." Case Reports in Cardiology 2017 (2017): 1–3. http://dx.doi.org/10.1155/2017/9157625.

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Lyme disease is caused by the spirochete Borrelia burgdorferi and is carried to human hosts by infected ticks. There are nearly 30,000 cases of Lyme disease reported to the CDC each year, with 3-4% of those cases reporting Lyme carditis. The most common manifestation of Lyme carditis is partial heart block following bacterial-induced inflammation of the conducting nodes. Here we report a 45-year-old gentleman that presented to the hospital with intense nonradiating chest pressure and tightness. Lab studies were remarkable for elevated troponins. EKG demonstrated normal sinus rhythm with mild S
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10

Ozdenerol, Esra, Rebecca Michelle Bingham-Byrne, and Jacob Daniel Seboly. "The Effects of Lifestyle on the Risk of Lyme Disease in the United States: Evaluation of Market Segmentation Systems in Prevention and Control Strategies." International Journal of Environmental Research and Public Health 18, no. 24 (2021): 12883. http://dx.doi.org/10.3390/ijerph182412883.

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The aim of this study was to investigate lifestyles at risk of Lyme disease, and to geographically identify target populations/households at risk based on their lifestyle preferences. When coupled with geographically identified patient health information (e.g., incidence, diagnostics), lifestyle data provide a more solid base of information for directing public health objectives in minimizing the risk of Lyme disease and targeting populations with Lyme-disease-associated lifestyles. We used an ESRI Tapestry segmentation system that classifies U.S. neighborhoods into 67 unique segments based on
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11

Radesich, Cinzia, Eva Del Mestre, Kristen Medo, et al. "Lyme Carditis: From Pathophysiology to Clinical Management." Pathogens 11, no. 5 (2022): 582. http://dx.doi.org/10.3390/pathogens11050582.

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Cardiac involvement is a rare but relevant manifestation of Lyme disease that frequently presents as atrioventricular block (AVB). Immune-mediated injury has been implicated in the pathogenesis of Lyme carditis due to possible cross-reaction between Borrelia burgdorferi antigens and cardiac epitopes. The degree of the AVB can fluctuate rapidly, with two-thirds of patients progressing to complete AVB. Thus, continuous heart rhythm monitoring is essential, and a temporary pacemaker may be necessary. Routinely permanent pacemaker implantation, however, is contraindicated because of the frequent t
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12

Bremell, D., and L. Dotevall. "Oral doxycycline for Lyme neuroborreliosis with symptoms of encephalitis, myelitis, vasculitis or intracranial hypertension." European Journal of Neurology 21, no. 9 (2014): 1162–67. http://dx.doi.org/10.1111/ene.12420.

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13

Nykytyuk, S., S. Klymnyuk, and L. Levytska. "SINUS BRADYCARDIA AS AN EARLY MARKER OF HEART DAMAGE IN A GIRL WITH LYME DISEASE (CASE REPORT AND MINI REVIEW)." East European Scientific Journal 3, no. 4(68) (2021): 4–10. http://dx.doi.org/10.31618/essa.2782-1994.2021.3.68.22.

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Objectives Early clinical markers of Lyme carditis and other life-threatening prognostic factors due to complications of borreliа infection are still the beginning of active research by scientists. The literature describes a small number of cases of Lyme carditis with arrhythmias or cardiac conduction disorders. Material and methods We reviewed the case of a 14-year-old girl. LC was diagnosed on the basis of history of disease, physical examination, laboratory examination data (positive anti-borrelia IgM in ELISA with confirmation in immunoblot. The presence of B. burgdorferi s.l. was detected
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14

Packard, Russell C., and Lesley P. Ham. "EEG Biofeedback in the Treatment of Lyme Disease:." Journal of Neurotherapy 1, no. 3 (1995): 22–31. http://dx.doi.org/10.1300/j184v01n03_04.

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15

Zainal, Abir, Amir Hanafi, Ninad Nadkarni, Mahmood Mubasher, Deeraj Lingutla, and Ryan Hoefen. "Lyme carditis presenting as atrial fibrillation." BMJ Case Reports 12, no. 4 (2019): e228975. http://dx.doi.org/10.1136/bcr-2018-228975.

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The incidence of Lyme disease in the USA is 8 per 100 000 cases and 95% of those occur in the Northeastern region. Cardiac involvement occurs in only 1% of untreated patients. We describe the case of a 46-year-old man who presented with chest pressure, dyspnoea, palpitations and syncope. He presented initially with atrial fibrillation with rapid ventricular response, a rare manifestation of Lyme carditis. In another hospital presentation, he had varying degrees of atrioventricular block including Mobitz I second-degree heart block. After appropriate antibiotic treatment, he made a full recover
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16

Kerndt, Connor C., John A. Bills, Zaid J. Shareef, Alexander M. Balinski, Daniel F. Summers, and Jose M. Tan. "Early Disseminated Lyme Carditis Inducing High-Degree Atrioventricular Block." Case Reports in Cardiology 2020 (June 4, 2020): 1–6. http://dx.doi.org/10.1155/2020/5309285.

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Lyme disease is the most common tick-borne illness in the United States due to Borrelia burgdorferi infection. This case demonstrates a 20-year-old male patient presenting with complaints of annular skin rash, malaise, fever, and lightheadedness after significant outdoor exposure. Physical exam revealed multiple large targetoid lesions on the back and extremities. The rash had raised borders and centralized clearing consistent with erythema migrans chronicum. Electrocardiogram (ECG) revealed a high-degree atrioventricular (AV) block. The patient was started on intravenous ceftriaxone due to cl
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17

Myndziv, K. V., N. I. Yarema, N. Ya Vereshchahina, V. I. Bondarchuk, U. P. Hevko, and O. V. Vayda. "Application of diagnostic methods in the verification of Lyme carditis (clinical case)." Medicni perspektivi 28, no. 3 (2023): 205–12. http://dx.doi.org/10.26641/2307-0404.2023.3.289228.

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The aim of the reserch was to investigate the genotype of the pathogen in a patient with Lyme carditis and to analyze the course of the disease in the process of etiotropic treatment. The article describes a clinical case of infectious myocarditis associated with Lyme disease in a 49-year-old patient. The value of modern diagnostics technologies in diagnosis determination was described. The course of the disease and the results of treatment of the patient were analyzed. The severe rhythm and conduction disorders were revealed with the method of Holter monitoring: AV-block of the first degree,
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18

Myndziv, K.V., N.I. Yarema, N.Ya. Vereshchahina, V.I. Bondarchuk, U.P. Hevko, and O.V. Vayda. "Application of diagnostic methods in the verification of Lyme carditis (clinical case)." Medicni perspektivi 28, no. 3 (2023): 205–12. https://doi.org/10.26641/2307-0404.2023.3.289228.

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The aim of the reserch was to investigate the genotype of the pathogen in a patient with Lyme carditis and to analyze the course of the disease in the process of etiotropic treatment. The article describes a clinical case of infectious myocarditis associated with Lyme disease in a 49-year-old patient. The value of modern diagnostics technologies in diagnosis determination was described. The course of the disease and the results of treatment of the patient were analyzed. The severe rhythm and conduction disorders were revealed with the method of Holter monitoring: AV-block of the first degree,
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19

Lytvyn, Halyna, Natella Basa, Khrystyna Slivinska-Kurchak, and Iryna Avramenko. "First-degree atrioventricular block in 14-year-old child due to Lyme disease." Journal of Infection in Developing Countries 16, no. 04 (2022): 726–28. http://dx.doi.org/10.3855/jidc.15071.

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Lyme disease is an infectious disease caused by bacteria of the Borrelia burgdorferi sensu lato (Bbsl) complex and is characterized by predominant lesions of the skin, cardiovascular system, nervous system and musculoskeletal system. We have described a clinical case of first-degree atrioventricular block in a 14-year-old boy caused by Lyme borreliosis. The disease started with the manifestations of cardiovascular system involvement. The patient and his parents did not recall observing a tick bite or manifestation of erythema migrans (EM). The boy was prescribed doxycycline. Three weeks after
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20

Pritulina, Yu G., L. A. Chernyshova, G. G. Salomakhin, et al. "Cardiac lesions in patients with Lyme borreliosis." Infekcionnye bolezni 19, no. 1 (2021): 83–88. http://dx.doi.org/10.20953/1729-9225-2021-1-83-88.

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Acute infectious diseases can potentially affect the cardiovascular system. Objective. To demonstrate the need for dynamic monitoring and treatment of cardiovascular disorders in patients with tickborne borreliosis. Patients and methods. This study included 142 patients with laboratory-confirmed tick-borne borreliosis. We analyzed clinical symptoms, results of laboratory testing, and electrocardiography (ECG) findings. Results. Almost one-fifth of all patients (18%) had complaints indicating cardiovascular lesions (both in the group under 60 years of age and in the group of elderly patients).
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21

Dhliwayo, Nyembezi, Rana Wajahat, Andriy Havrylyan, Alvia Moid, Walid Khayr, and Charles P. Barsano. "Lyme Disease: An Autoimmunity-Based “Destructive Thyroiditis” or Just Another “Non-Thyroidal Illness”?" Journal of the Endocrine Society 5, Supplement_1 (2021): A940—A941. http://dx.doi.org/10.1210/jendso/bvab048.1922.

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Abstract There is considerable evidence that some Borrelial (Lyme spirochetal) proteins share significant antigenic properties with several thyroid-related proteins (e.g. TSH receptor, thyroglobulin, thyroid peroxidase) and can induce thyroid autoimmunity, sometimes associated with Hashimoto’s thyroiditis and perhaps also a “destructive thyroiditis” such as “silent” thyroiditis or “Hashitoxicosis.” As an acute illness, Lyme disease may also constitute a “non-thyroidal illness” capable of perturbing thyroid function tests without causing thyroid dysfunction. We report a 22-year old woman admitt
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Budaeva, Iryna, Heorhii Revenko, Liubov Kodola, and Svitlana Ryasik. "Modern Epidemiological Features of Lyme-borreliosis and Diagnostic Criteria of «Minor» Forms of Myocarditis." Family Medicine, no. 6 (December 30, 2016): 94–97. http://dx.doi.org/10.30841/2307-5112.6.2016.249523.

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This paper shows the epidemiological characteristics of Lyme-borreliosis in Dnipropetrovsk region, which presents urbanic environment. The greatest incidence of the disease was determined in working age population. The possibility of heart involvement in the «minor» forms is proved; the later are diagnosed with the means of ECG and CFK-MB evaluation.
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Budaeva, Iryna, Heorhii Revenko, Liubov Kodola, and Svitlana Ryasik. "Modern Epidemiological Features of Lyme-borreliosis and Diagnostic Criteria of «Minor» Forms of Myocarditis." Family Medicine, no. 6 (December 26, 2016): 94–97. https://doi.org/10.30841/2307-5112.6.2016.249523.

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This paper shows the epidemiological characteristics of Lyme-borreliosis in Dnipropetrovsk region, which presents urbanic environment. The greatest incidence of the disease was determined in working age population. The possibility of heart involvement in the «minor» forms is proved; the later are diagnosed with the means of ECG and CFK-MB evaluation.
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24

Chirva, D. V. "Does Olson’s animalism put end to personal identity debate?" Omsk Scientific Bulletin. Series Society. History. Modernity 6, no. 2 (2021): 107–12. http://dx.doi.org/10.25206/2542-0488-2021-6-2-107-112.

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Theory of Eric Olson’s animalism is evaluated in the article in relation to his debate with the proponents of psychological approach to personal identity problem. Olson aims to show the irrelevance of psychology to the issue and to finish the debate by means of introducing the fetus problem. It is argued that theory of animalism has its certain strong points in comparison with Lynne Baker’s constitution view and Jeff McMahan’s embodied part approach; it does not contain any contradictions and rests on few theoretical assumptions. Nevertheless, it is claimed that animalism does not finish the d
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Sur, Maria Lucia, Bogdan-Stefan Moldovan, Diana Mocanu, et al. "Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review." Life 12, no. 7 (2022): 940. http://dx.doi.org/10.3390/life12070940.

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Viral infections are a key issue in modern medicine. SARS-CoV-2 infection confirms that we are not sufficiently prepared for these unforeseen infections. The COVID-19 pandemic has cultivated a great sense of fear and distrust in patients. If viral infections, in this case, SARS-CoV-2, overlap with another infection, the symptoms are prolonged and worsened, and complications may occur. Starting from an objective clinical finding of a patient they had in follow-up and treatment, the authors present the problems of the diseases the patient suffered from. These are described as reviews so that rea
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Wendel Neto, Silvano. "Current concepts on the transmission of bacteria and parasites by blood components." Sao Paulo Medical Journal 113, no. 6 (1995): 1036–52. http://dx.doi.org/10.1590/s1516-31801995000600007.

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Several bacterial and parasite transfusion-transmitted diseases have been described in the medical literature. This review deals with the main bacterial (Syphilis, Lyme disease, Gram positive and Gram negative agents), parasite (Chagas disease, malaria, leishmaniasis, toxoplasmosis and babesiosis) and rickettsial diseases that are carried by blood products. Preventional aspects (e.g. storage, screening tests, use of leukocyte-depleted components), diagnosis, geographical distribution and the incidence of these transfusional hazards are also discussed.
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Iyer, Radha, Ogori Kalu, Joye Purser, Steven Norris, Brian Stevenson, and Ira Schwartz. "Linear and Circular Plasmid Content in Borrelia burgdorferi Clinical Isolates." Infection and Immunity 71, no. 7 (2003): 3699–706. http://dx.doi.org/10.1128/iai.71.7.3699-3706.2003.

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ABSTRACT The genome of Borrelia burgdorferi, the etiologic agent of Lyme disease, is composed of a linear chromosome and more than 20 linear and circular plasmids. Typically, plasmid content analysis has been carried out by pulsed-field gel electrophoresis and confirmed by Southern hybridization. However, multiple plasmids of virtually identical sizes (e.g., lp28 and cp32) complicate the interpretation of such data. The present study was undertaken to investigate the complete plasmid complements of B. burgdorferi clinical isolates cultivated from patients from a single region where early Lyme
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Rochlin, Ilia, and Alvaro Toledo. "Emerging tick-borne pathogens of public health importance: a mini-review." Journal of Medical Microbiology 69, no. 6 (2020): 781–91. http://dx.doi.org/10.1099/jmm.0.001206.

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Ticks are the most important vectors of human pathogens, leading to increased public health burdens worldwide. Tick-borne pathogens include viruses (e.g. tick-borne encephalitis and Powassan); bacteria, such as the causative agents of Lyme disease, spotted fever rickettsiosis and human anaplasmosis; and malaria-like protozoan parasites causing babesiosis. Tick-borne diseases are emerging due to the geographical expansion of their tick vectors, especially in the northern hemisphere. Two examples of this phenomenon are Ixodes scapularis and Amblyomma americanum, which have expanded their ranges
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Sapozhnikova, V. V., and A. L. Bondarenko. "Multifactorial analysis of clinical laboratory signs, the levels of IL-17A, IL-23, IL-33, IL-35, and specific antibodies in the serum of patients with Lyme borreliosis without erythema migrans." Russian Medical Inquiry 4, no. 11 (2020): 676–81. http://dx.doi.org/10.32364/2587-6821-2020-4-11-676-681.

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Aim: to determine the association between clinical laboratory parameters, the production of cytokines (IL-17A, -23, -33, -35), and specific IgM and IgG in the serum of patients with Lyme borreliosis without erythema migrans. Patients and Methods: complete blood count, the concentrations of IL-17A, -23, -33, -35, and the levels of specific IgM and IgG were measured during acute infection and convalescence (n=30). The control group included age- and sex-matched healthy individuals (n=30). Statistical analysis was performed using the StatSoft Statistica v 10.0 software (parametric and non-paramet
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Massara, M., L. Zappelli, A. Lanari, et al. "LYME AND DENGUE FEVER: FROM BANGLADESH TO ITALY." European Heart Journal Supplements 26, Supplement_2 (2024): ii59. http://dx.doi.org/10.1093/eurheartjsupp/suae036.134.

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Abstract Background Dengue fever (Flavivirus) and Lyme disease (Borrelia burgdorferi) are rare tropical infectious diseases transmitted by hematophagous vectors (Aedes mosquitoes and ticks, respectively), and they are extremely uncommon in Italy. In European countries, both represent a public health concern as they manifest as imported diseases. Case Report A 54–year–old man from Bangladesh was admitted with symptoms of fever, dyspnea, and pericarditic chest pain. Laboratory and imaging examinations revealed severe acute respiratory failure secondary to left lower lobe pneumonia and pleuroperi
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Porwancher, Richard B., C. Greg Hagerty, Jianqing Fan, et al. "Multiplex Immunoassay for Lyme Disease Using VlsE1-IgG and pepC10-IgM Antibodies: Improving Test Performance through Bioinformatics." Clinical and Vaccine Immunology 18, no. 5 (2011): 851–59. http://dx.doi.org/10.1128/cvi.00409-10.

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ABSTRACTThe Centers for Disease Control and Prevention currently recommends a 2-tier serologic approach to Lyme disease laboratory diagnosis, comprised of an initial serum enzyme immunoassay (EIA) for antibody toBorrelia burgdorferifollowed by supplementary IgG and IgM Western blotting of EIA-positive or -equivocal samples. Western blot accuracy is limited by subjective interpretation of weakly positive bands, false-positive IgM immunoblots, and low sensitivity for detection of early disease. We developed an objective alternative second-tier immunoassay using a multiplex microsphere system tha
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Stupica, Daša, Fajko F. Bajrović, Rok Blagus, et al. "Clinical manifestations and long‐term outcome of early Lyme neuroborreliosis according to the European Federation of Neurological Societies diagnostic criteria (definite versus possible) in central Europe. A retrospective cohort study." European Journal of Neurology 28, no. 9 (2021): 3155–66. http://dx.doi.org/10.1111/ene.14962.

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Flynn, Connor, Elham Rezaee, and Anna Ignaszak. "A Detection of Borrelia Burgdorferi, the Lyme Disease-Causing Bacteria, Using a Biomimetic Electrochemical Assay." ECS Meeting Abstracts MA2025-01, no. 59 (2025): 2810. https://doi.org/10.1149/ma2025-01592810mtgabs.

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Lyme disease, caused by infection with pathogenic Borrelia bacteria, has emerged as a pervasive illness throughout North America and many other regions of the world in recent years, owing in part to climate-mediated habitat expansion of the tick vectors. Standard diagnostic testing has remained largely unchanged over the past several decades and is indirect, relying on the detection of antibodies against the Borrelia pathogen rather than the detection of the pathogen itself. The development of new rapid, point-of-care tests for Lyme disease that directly detect the pathogen could drastically i
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Gardner, Allison M., Natalie C. Pawlikowski, Sarah A. Hamer, et al. "Landscape features predict the current and forecast the future geographic spread of Lyme disease." Proceedings of the Royal Society B: Biological Sciences 287, no. 1941 (2020): 20202278. http://dx.doi.org/10.1098/rspb.2020.2278.

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Lyme disease, the most prevalent vector-borne disease in North America, is increasing in incidence and geographic distribution as the tick vector, Ixodes scapularis , spreads to new regions. We re-construct the spatial-temporal invasion of the tick and human disease in the Midwestern US, a major focus of Lyme disease transmission, from 1967 to 2018, to analyse the influence of spatial factors on the geographic spread. A regression model indicates that three spatial factors—proximity to a previously invaded county, forest cover and adjacency to a river—collectively predict tick occurrence. Vali
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Mesbah-Oskui, L., O. Marais, J. Alabkal, N. Randhawa, and MM Mezei. "P.066 A 65 year-old male with subacute asymmetric, proximal more than distal upper extremity weakness with associated paresthesias and pain." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 51, s1 (2024): S34. http://dx.doi.org/10.1017/cjn.2024.172.

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Background: Neuroborreliosis affects approximately 10-15% of people with untreated Lyme disease and typically declares itself 2-18 weeks after infection. North American neuroborreliosis often manifests with cranial nerve palsy, meningitis, and/or radiculoneuritis. Methods: Here we describe a case of North American neuroborreliosis and also highlight some of the rare manifestations of systemic Lyme disease. A 65-year old male presented with a subacute history of progressive upper extremity weakness, neck pain, and headache. This occurred in the context of a recent tick exposure. Results: MRI of
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Rudd-Barnard, Alexandra, Sarah Jarvandi, Roxanne Rapoport, Sue Smith, and Natalia Witkowska. "A-79 Case Series Evaluating Quantitative Electroencephalograph and Neuropsychological Function in Neurological Lyme Disease." Archives of Clinical Neuropsychology 36, no. 6 (2021): 1123–24. http://dx.doi.org/10.1093/arclin/acab062.97.

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Abstract Objectives The purpose of this study was to investigate the characteristics of physician diagnosed Neurological Lyme disease (NLD) using Quantitative EEG and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). We hypothesize that findings would include more slow wave (Delta/Theta) activity that is consistent with the severity reported dysfunction. Methods Subjects consisted of four adult females with a physician provided diagnosis of NLD. EEG was recorded from 21 sites during an eyes open and eyes-closed resting conditions. Raw EEG data was made quantifiabl
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Shushkovska, Yu Yu, O. I. Afanasiuk, and R. V. Matyash. "Clinical case of borreliosis myocarditis." Reports of Vinnytsia National Medical University 24, no. 2 (2020): 232–35. http://dx.doi.org/10.31393/reports-vnmedical-2020-24(2)-06.

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Annotation. The purpose of the work is to demonstrate the peculiarities of its course, modern methods of diagnosis and treatment on the example of a clinical case of borreliosis myocarditis. According to the results of the patient's ECG, a transient atrio-ventricular block of the first degree was established. The results of general clinical methods of examination of the patient generally corresponded to the reference values. According to the results of Holter ECG monitoring, a diagnosis of mild myocarditis, heart failure I, functional class I, with preserved ejection fraction (50 %) of the lef
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Tully, Brenden G., and Jason F. Huntley. "Mechanisms Affecting the Acquisition, Persistence and Transmission of Francisella tularensis in Ticks." Microorganisms 8, no. 11 (2020): 1639. http://dx.doi.org/10.3390/microorganisms8111639.

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Over 600,000 vector-borne disease cases were reported in the United States (U.S.) in the past 13 years, of which more than three-quarters were tick-borne diseases. Although Lyme disease accounts for the majority of tick-borne disease cases in the U.S., tularemia cases have been increasing over the past decade, with >220 cases reported yearly. However, when comparing Borrelia burgdorferi (causative agent of Lyme disease) and Francisella tularensis (causative agent of tularemia), the low infectious dose (<10 bacteria), high morbidity and mortality rates, and potential transmission of tular
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Dr.h.c., Andreas Ludwig Kalcker. "Clarifying The Science of Chlorine Dioxide Solution (CDS): Addressing Misinformation and Establishing Evidence for Medical Use." INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH AND ANALYSIS 08, no. 03 (2025): 1367–73. https://doi.org/10.5281/zenodo.15093881.

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Chlorine Dioxide Solution (CDS), an aqueous preparation of chlorine dioxide (ClO₂) gas, is promoted as a treatment for conditions including COVID-19, cancer, Lyme disease, and methicillin-resistant Staphylococcus aureus (MRSA), yet lacks robust clinical validation. This review assesses ClO₂’s chemical properties, distinguishing gaseous ClO₂ (hazardous when inhaled at >0.1 ppm) from CDS (safe and effective at < 1 mg/L for disinfection and potential therapy). As a selective oxidant, CDS exhibits biocidal efficacy without forming trihalomethanes, unlike sodium chlorite (NaClO₂)-based
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Chojnowska, Sylwia, Alina Kępka, Sławomir Dariusz Szajda, Napoleon Waszkiewicz, Marcin Bierć, and Krzysztof Zwierz. "Exoglycosidase markers of diseases." Biochemical Society Transactions 39, no. 1 (2011): 406–9. http://dx.doi.org/10.1042/bst0390406.

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Exoglycosidases are hydrolases involved in lysosomal degradation of oligosaccharide chains of glycoconjugates (glycoproteins, glycolipids and proteoglycans). In tissues and body fluids, a higher exoglycosidase specific activity is found in N-acetyl-β-hexosaminidase, than β-glucuronidase, α-L-fucosidase, β-galactosidase, α-mannosidase and α-glucosidase. Determination of exoglycosidases (especially N-acetyl-β-hexosaminidase and β-glucuronidase) in body fluids could be an inexpensive, easy to perform and sensitive test for pathological evaluation, as well as in screening and monitoring many disea
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Taylor, Michael A. "Lost & Found: 200.Thomas Hawkins FGS (22 July 1810 - 15 October 1889)." Geological Curator 5, no. 3 (1989): 112–14. http://dx.doi.org/10.55468/gc632.

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Michael Taylor (Leicestershire Museums, Arts and Records Service, 96 New Walk, Leicester LEI 6TD) writes: 'Thomas Hawkins of Glastonbury has generally been regarded as an archetypal eccentric collector, who accumulated one of the finest collections of Liassic fossil marine reptiles from around Street and Glastonbury in Somerset, with a smaller proportion from Lyme Regis and Charmouth in Dorset. Although by no means forgotten (e.g. Blanford 1890; Owen 1894; Howe et ^.1981; McGowan 1983; McGarvie 1987), he has been the subject of little if any primary research since the biography of Bulleid (194
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Armstrong, Mary A. "NEXT WEEK!! — : DESIRE, DOMESTIC MELODRAMA, AND THE EXTRAVAGANT PROLIFERATIONS OFEAST LYNNE." Victorian Literature and Culture 43, no. 4 (2015): 745–64. http://dx.doi.org/10.1017/s1060150315000248.

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Ellen Wood'sEast Lynne(1861) exhibits the exhilarating characteristics of a Victorian sensation novel and then some: degenerate aristocracy, a sneering villain, flight, adultery, a child born out of wedlock, disfigurement, disguise, extended deathbed scenes, murder, and more (e.g., fake accents, false identities, an electrifying homicide trial, and a spectacular train wreck). But at the center of all the disaster, transgression, pathos, coincidence, and extremity,East Lynneis (mainly) the story of the aptly-named Isabel Vane, the beloved but patently bored wife who abandons her husband and chi
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Malenica, M., L. J. Cvitanović-Šojat, R. G. Juraški, and G. Tešović. "P22.11 EEG as a predictor of Lyme disease in a child with a peripheral facial palsy." European Journal of Paediatric Neurology 15 (May 2011): S122. http://dx.doi.org/10.1016/s1090-3798(11)70425-1.

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Shi, Wenyuan, Zhaomin Yang, Yongzhi Geng, Lawrence E. Wolinsky, and Michael A. Lovett. "Chemotaxis in Borrelia burgdorferi." Journal of Bacteriology 180, no. 2 (1998): 231–35. http://dx.doi.org/10.1128/jb.180.2.231-235.1998.

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ABSTRACT Borrelia burgdorferi is a motile spirochete which has been identified as the causative microorganism in Lyme disease. The physiological functions which govern the motility of this organism have not been elucidated. In this study, we found that motility of B. burgdorferi required an environment similar to interstitial fluid (e.g., pH 7.6 and 0.15 M NaCl). Several methods were used to detect and measure chemotaxis of B. burgdorferi. A number of chemical compounds and mixtures were surveyed for the ability to induce positive and negative chemotaxis of B. burgdorferi. Rabbit serum was fou
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Gagné, Julie. "Henderson, Errol A., Democracy and War. The End of an Illusion ?, Boulder, co, Lynne Rienner, 2002, 165 p." Études internationales 34, no. 3 (2003): 478. http://dx.doi.org/10.7202/038666ar.

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Leite, R. Almeida, M. Almeida, A. Costa, J. Alcafache, and A. Mesquita. "First psychotic episode as first manifestation of lyme disease: Case report." European Psychiatry 64, S1 (2021): S813. http://dx.doi.org/10.1192/j.eurpsy.2021.2148.

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IntroductionLyme disease (LD) is caused by the spirochete Borrelia burgdorferi (Bb) and has been reported to be associated with various psychiatric presentations.ObjectivesTo report a case with LD and to highlight the importance of differential diagnosis in a first psychotic episode.MethodsCase report and non-systematic review of the literature.Results A woman aged 31 was admitted to the psychiatric department, after a car accident with a mortal victim, due to a first psychotic episode with visual hallucinations, disorientation in time and space, persecutory and grandiosity delusions. She had
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Lager, Malin, Peter Wilhelmsson, Andreas Matussek, Per-Eric Lindgren, and Anna J. Henningsson. "Molecular Detection of Borrelia Bacteria in Cerebrospinal Fluid-Optimisation of Pre-Analytical Sample Handling for Increased Analytical Sensitivity." Diagnostics 11, no. 11 (2021): 2088. http://dx.doi.org/10.3390/diagnostics11112088.

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The main tools for clinical diagnostics of Lyme neuroborreliosis (LNB) are based on serology, i.e., detection of antibodies in cerebrospinal fluid (CSF). In some cases, PCR may be used as a supplement, e.g., on CSF from patients with early LNB. Standardisation of the molecular methods and systematic evaluation of the pre-analytical handling is lacking. To increase the analytical sensitivity for detection of Borrelia bacteria in CSF by PCR targeting the 16S rRNA gene, parameters were systematically evaluated on CSF samples spiked with a known amount of cultured Borrelia bacteria. The results sh
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Dixon, Gabriel, Andrew S. Marriott, Graham Stelfox, Chris Dunkerley, and Sven P. Batke. "How do red deer react to increased visitor numbers? A case study on human-deer encounter probability and its effect on cortisol stress responses." Nature Conservation 43 (February 26, 2021): 55–78. http://dx.doi.org/10.3897/natureconservation.43.56266.

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The numbers of visitors to greenspaces in the United Kingdom has increased over the last few years as the health benefits of spending time in greenspaces have become better known. This has led to problems for conservation ecologists due to increased numbers of reported human-wildlife encounters. Deer are often found in public spaces and are of particular concern. Previous research suggests elevated levels of stress hormones (e.g., cortisol) in deer is a result of increased human activity. This has been linked to several negative effects on the deer’s health. From a practitioner’s point of view
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Dixon, Gabriel, Andrew S. Marriott, Graham Stelfox, Chris Dunkerley, and Sven P. Batke. "How do red deer react to increased visitor numbers? A case study on human-deer encounter probability and its effect on cortisol stress responses." Nature Conservation 43 (February 26, 2021): 55–78. https://doi.org/10.3897/natureconservation.43.56266.

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The numbers of visitors to greenspaces in the United Kingdom has increased over the last few years as the health benefits of spending time in greenspaces have become better known. This has led to problems for conservation ecologists due to increased numbers of reported human-wildlife encounters. Deer are often found in public spaces and are of particular concern. Previous research suggests elevated levels of stress hormones (e.g., cortisol) in deer is a result of increased human activity. This has been linked to several negative effects on the deer's health. From a practitioner's point of view
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Gormally, M. J. "The effect of temperature on the duration of the egg stage of certain sciomyzid flies which predate Lymnae truncatula." Journal of Thermal Biology 10, no. 4 (1985): 199–203. http://dx.doi.org/10.1016/0306-4565(85)90040-3.

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