Artigos de revistas sobre o tema "Leukemia initiation and transformation"
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He, Jin, Anh Tram Nguyen e Yi Zhang. "KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia". Blood 117, n.º 14 (7 de abril de 2011): 3869–80. http://dx.doi.org/10.1182/blood-2010-10-312736.
Texto completo da fonteHurtz, Christian, Katerina Hatzi, Leandro Cerchietti, Melanie Braig, Eugene Park, Yong-mi Kim, Sebastian Herzog et al. "BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia". Journal of Experimental Medicine 208, n.º 11 (12 de setembro de 2011): 2163–74. http://dx.doi.org/10.1084/jem.20110304.
Texto completo da fonteMendoza-Castrejon, Jonny, Emily B. Casey, Riddhi M. Patel, Elisabeth Denby e Jeffrey Magee. "Fetal MLL-ENL Initiation Induces Developmental Stage-Specific Programs That Restrict Transformation and Depend on MLL3". Blood 142, Supplement 1 (28 de novembro de 2023): 950. http://dx.doi.org/10.1182/blood-2023-178865.
Texto completo da fonteUgale, Amol Sanjay, Gudmundur Logi Norddahl, Martin Wahlestedt, Petter Säwén, Pekka Jaako, Cornelis J. H. Pronk, Shamit Soneji, Jorg Cammenga e David Bryder. "Hematopoietic Stem Cells Are Intrinsically Protected Against MLL-ENL Mediated Transformation". Blood 124, n.º 21 (6 de dezembro de 2014): 839. http://dx.doi.org/10.1182/blood.v124.21.839.839.
Texto completo da fonteOkeyo-Owuor, Theresa, Yanan Li, Riddhi M. Patel, Wei Yang, Emily B. Casey, Andrew S. Cluster, Shaina N. Porter, David Bryder e Jeffrey A. Magee. "The efficiency of murine MLL-ENL–driven leukemia initiation changes with age and peaks during neonatal development". Blood Advances 3, n.º 15 (12 de agosto de 2019): 2388–99. http://dx.doi.org/10.1182/bloodadvances.2019000554.
Texto completo da fonteBunworasate, Udomsak, Hilal Arnouk, Hans Minderman, Kieran L. O'Loughlin, Sheila N. J. Sait, Maurice Barcos, Carleton C. Stewart e Maria R. Baer. "Erythropoietin-dependent transformation of myelodysplastic syndrome to acute monoblastic leukemia". Blood 98, n.º 12 (1 de dezembro de 2001): 3492–94. http://dx.doi.org/10.1182/blood.v98.12.3492.
Texto completo da fonteTsuruta-Kishino, Takako, Keisuke Kataoka, Hiroshi Kobayashi, Junji Koya, Kensuke Narukawa, Tomohiko Sato e Mineo Kurokawa. "Loss Of p53 Induces Leukemic Transformation In a Murine Model Of JAK2V617F-Induced Polycythemia Vera". Blood 122, n.º 21 (15 de novembro de 2013): 269. http://dx.doi.org/10.1182/blood.v122.21.269.269.
Texto completo da fonteWagenblast, Elvin, Joana Araújo, Olga I. Gan, Sarah K. Cutting, Alex Murison, Jessica L. McLeod, Gabriela Krivdova et al. "A Human Model of Down Syndrome Associated Leukemia Reveals Different Cell of Origins for Initiation and Progression". Blood 136, Supplement 1 (5 de novembro de 2020): 11–12. http://dx.doi.org/10.1182/blood-2020-135867.
Texto completo da fonteWang, Pin-Yi, Fay Young, Chun-Yu Chen, Brett M. Stevens, Sarah J. Neering, Randall M. Rossi, Timothy Bushnell et al. "The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19ARF gene". Blood 112, n.º 10 (15 de novembro de 2008): 4184–92. http://dx.doi.org/10.1182/blood-2008-02-142190.
Texto completo da fonteSharma, Ritul, Chunfen Zhang e Aru Narendran. "The Small-Molecule E26-Transformation-Specific Inhibitor TK216 Attenuates the Oncogenic Properties of Pediatric Leukemia". Genes 14, n.º 10 (8 de outubro de 2023): 1916. http://dx.doi.org/10.3390/genes14101916.
Texto completo da fonteOhlsson, Ewa, Marie Sigurd Hasemann, Anton Willer, Felicia Kathrine Bratt Lauridsen, Nicolas Rapin, Johan Jendholm e Bo Torben Porse. "Initiation of MLL-rearranged AML is dependent on C/EBPα". Journal of Experimental Medicine 211, n.º 1 (23 de dezembro de 2013): 5–13. http://dx.doi.org/10.1084/jem.20130932.
Texto completo da fonteYokoyama, Akihiko, e Hiroshi Okuda. "The Molecular Mechanism of Transcriptional Activation By MLL-AEP Fusion Proteins". Blood 126, n.º 23 (3 de dezembro de 2015): 2435. http://dx.doi.org/10.1182/blood.v126.23.2435.2435.
Texto completo da fonteHorton, Sarah J., Vanessa Walf-Vorderwülbecke, Steve J. Chatters, Neil J. Sebire, Jasper de Boer e Owen Williams. "Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities". Blood 113, n.º 20 (14 de maio de 2009): 4922–29. http://dx.doi.org/10.1182/blood-2008-07-170480.
Texto completo da fonteFishman, Hila, Shreyas Madiwale, Ifat Geron, Vase Bari, Wouter Van Loocke, Yael Kirschenbaum, Itamar Ganmore et al. "ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells". Blood 139, n.º 3 (20 de janeiro de 2022): 399–412. http://dx.doi.org/10.1182/blood.2020010405.
Texto completo da fonteCai, Xiongwei, Yoshihiro Hayashi, Mark Wunderlich, Nancy A. Speck, James C. Mulloy, Gang Huang e Yi Zheng. "Loss of Function RUNX1 Mutations Restrict Protein Biosynthesis during Pre-Leukemia and MDS Transition but Not after Leukemic Transformation". Blood 128, n.º 22 (2 de dezembro de 2016): 3860. http://dx.doi.org/10.1182/blood.v128.22.3860.3860.
Texto completo da fonteGasic, Vladimir, Teodora Karan-Djurasevic, Djordje Pavlovic, Branka Zukic, Sonja Pavlovic e Natasa Tosic. "Diagnostic and Therapeutic Implications of Long Non-Coding RNAs in Leukemia". Life 12, n.º 11 (2 de novembro de 2022): 1770. http://dx.doi.org/10.3390/life12111770.
Texto completo da fonteMelo, Junia V., e Michael W. N. Deininger. "Biology of chronic myelogenous leukemia—signaling pathways of initiation and transformation". Hematology/Oncology Clinics of North America 18, n.º 3 (junho de 2004): 545–68. http://dx.doi.org/10.1016/j.hoc.2004.03.008.
Texto completo da fonteJoffre, Carine, Charlotte Ducau, Laura Poillet-Perez, Charly Courdy e Véronique Mansat-De Mansat-De Mas. "Autophagy a Close Relative of AML Biology". Biology 10, n.º 6 (18 de junho de 2021): 552. http://dx.doi.org/10.3390/biology10060552.
Texto completo da fonteJamrog, Laura, Guillaume Chemin, Vincent Fregona, Lucie Coster, Marlène Pasquet, Chloé Oudinet, Nelly Rouquié et al. "PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice". Proceedings of the National Academy of Sciences 115, n.º 41 (26 de setembro de 2018): 10357–62. http://dx.doi.org/10.1073/pnas.1721678115.
Texto completo da fonteHorton, Sarah J., Vanessa Walf-Vorderwülbecke, Steve J. Chatters, Neil J. Sebire, Jasper de Boer e Owen Williams. "Acute Myeloid Leukemia Induced by MLL-ENL Is Cured by Oncogene Ablation despite Acquisition of Complex Genetic Abnormalities". Blood 112, n.º 11 (16 de novembro de 2008): 3109. http://dx.doi.org/10.1182/blood.v112.11.3109.3109.
Texto completo da fonteQuéré, Ronan, Göran Karlsson, Falk Hertwig, Marianne Rissler, Beata Lindqvist, Thoas Fioretos, Peter Vandenberghe, Marilyn L. Slovak, Jörg Cammenga e Stefan Karlsson. "Smad4 binds Hoxa9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by Hoxa9 and leukemia transformation". Blood 117, n.º 22 (2 de junho de 2011): 5918–30. http://dx.doi.org/10.1182/blood-2010-08-301879.
Texto completo da fonteCai, Qi, Robin Jeannet, Hongjun Liu e ya-Huei Kuo. "CBFβ-SMMHC Impairs Erythroid Differentiation and Induces Expansion of Aberrant Megakaryocytic/Erythroid Progenitors Capable of Leukemia Initiation". Blood 124, n.º 21 (6 de dezembro de 2014): 2149. http://dx.doi.org/10.1182/blood.v124.21.2149.2149.
Texto completo da fonteEl-Haj, Nura, Wilson I. Gonsalves, Vinay Gupta, Jacob P. Smeltzer, Sameer A. Parikh, Preet P. Singh e Naseema Gangat. "Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia". Case Reports in Hematology 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/287479.
Texto completo da fonteCobaleda, C., N. Gutiérrez-Cianca, J. Pérez-Losada, T. Flores, R. Garcı́a-Sanz, M. González e I. Sánchez-Garcı́a. "A primitive hematopoietic cell is the target for the leukemic transformation in human Philadelphia-positive acute lymphoblastic leukemia". Blood 95, n.º 3 (1 de fevereiro de 2000): 1007–13. http://dx.doi.org/10.1182/blood.v95.3.1007.003k35_1007_1013.
Texto completo da fonteQuere, Ronan, Silja Andradottir, Ann Brun, Roman Zubarev, Göran Karlsson, Karin Olsson, Mattias Magnusson, Jörg Cammenga e Stefan Karlsson. "High Levels of the Adhesion Molecule CD44 on Leukemic Cells Generate Acute Myeloid Leukemia Relapse After Withdrawal of the Initial Transforming Event". Blood 116, n.º 21 (19 de novembro de 2010): 3154. http://dx.doi.org/10.1182/blood.v116.21.3154.3154.
Texto completo da fonteJeannet, Robin, Qi Cai, Hongjun Liu, Hieu Vu e Ya-Huei Kuo. "Alcam Mediated Interaction Regulates Normal Hematopoietic Stem Cell Function and Cbfβ-SMMHC Induced Leukemogenesis". Blood 120, n.º 21 (16 de novembro de 2012): 4091. http://dx.doi.org/10.1182/blood.v120.21.4091.4091.
Texto completo da fonteChaubey, Aditya, Chinavenmeni Subramani Velu, Shane Horman, Anil Jegga, Monica L. Guzman, Nancy Zeleznik-Le, Craig T. Jordan, Martin Carroll, Brian Gebelein e H. Leighton Grimes. "Intrinsic Requirement of MicroRNA In Hox-Based Leukemia Initiating Cell Maintenance". Blood 116, n.º 21 (19 de novembro de 2010): 4192. http://dx.doi.org/10.1182/blood.v116.21.4192.4192.
Texto completo da fonteMa, Haiqing, Saradhi Mallampati, Baohua Sun, Yun Gong, Véronique Lefebvre e Xiaoping Sun. "Sox4 Is Essential for Initiation and Progression of Acute Lymphoblastic Leukemia Induced by P190-BCR-ABL Transformation". Blood 118, n.º 21 (18 de novembro de 2011): 564. http://dx.doi.org/10.1182/blood.v118.21.564.564.
Texto completo da fonteCai, Qi, Robin Jeannet, Hongjun Liu e Ya-Huei Kuo. "Aberrant Megakaryocytic/Erythroid Progenitors Contributes To Transformation Of Cbfb-SMMHC Induced Acute Myeloid Leukemia". Blood 122, n.º 21 (15 de novembro de 2013): 1652. http://dx.doi.org/10.1182/blood.v122.21.1652.1652.
Texto completo da fonteWesolowski, Radoslaw, Elisabeth Kowenz-Leutz, Karin Zimmermann, Dorothea Dörr, Maria Hofstätter, Robert K. Slany, Alexander Mildner e Achim Leutz. "Myeloid transformation by MLL-ENL depends strictly on C/EBP". Life Science Alliance 4, n.º 1 (3 de novembro de 2020): e202000709. http://dx.doi.org/10.26508/lsa.202000709.
Texto completo da fonteAuberger, Patrick, e Alexandre Puissant. "Autophagy, a key mechanism of oncogenesis and resistance in leukemia". Blood 129, n.º 5 (2 de fevereiro de 2017): 547–52. http://dx.doi.org/10.1182/blood-2016-07-692707.
Texto completo da fonteZhang, Jing, Jing Wang, Yangang Liu, Harwin Sidik, Ken H. Young, Harvey F. Lodish e Mark D. Fleming. "Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation". Blood 113, n.º 6 (5 de fevereiro de 2009): 1304–14. http://dx.doi.org/10.1182/blood-2008-01-134262.
Texto completo da fonteKumar, Bijender, Lei Zhang, Yunan Miao, Gerald Wuenschell, Allen Lin, Vinod Pullarkat, Guido Marcucci, Robert Hickey e Ching-Cheng Chen. "Proteomics Profiling of Leukemia Derived Exosomes: A Potential Role in Leukemic Transformation". Blood 126, n.º 23 (3 de dezembro de 2015): 3857. http://dx.doi.org/10.1182/blood.v126.23.3857.3857.
Texto completo da fonteDudenhöffer-Pfeifer, Monika, e David Bryder. "Immunoediting is not a primary transformation event in a murine model of MLL-ENL AML". Life Science Alliance 1, n.º 4 (10 de julho de 2018): e201800079. http://dx.doi.org/10.26508/lsa.201800079.
Texto completo da fonteRoe, Jae-Seok, e Christopher R. Vakoc. "C/EBPα: critical at the origin of leukemic transformation". Journal of Experimental Medicine 211, n.º 1 (6 de janeiro de 2014): 1–4. http://dx.doi.org/10.1084/jem.20132530.
Texto completo da fonteChen, Shuying, Qing Rao, Haiyan Xing, Jing Yu, Huan Li, Min Wang e Jianxiang Wang. "Rac1 Gtpase Promotes Hematopoietic Stem Cell Migration, Self-Renewal and Participates in Leukemia Initiation and Maintenance". Blood 124, n.º 21 (6 de dezembro de 2014): 2923. http://dx.doi.org/10.1182/blood.v124.21.2923.2923.
Texto completo da fonteKuchenbauer, Florian, Tobias Berg, Sarah M. Mah, Milijana mirkovic-Hosle, Anisa Salmi, Jens Ruschmann, Andrew Muranyi et al. "Mir-223 Is Dispensable for the Onset of Acute Myeloid Leukemia". Blood 116, n.º 21 (19 de novembro de 2010): 501. http://dx.doi.org/10.1182/blood.v116.21.501.501.
Texto completo da fonteWang, Yingzi, Andrei V. Krivtsov, Amit U. Sinha, Trista North, Wolfram Goessling, Leonard I. Zon e Scott Armstrong. "β-Catenin Determines Developmental Stage Specific Transformation by Hox Genes." Blood 114, n.º 22 (20 de novembro de 2009): 385. http://dx.doi.org/10.1182/blood.v114.22.385.385.
Texto completo da fonteRopa, James, Nirmalya SAHA e Andrew G. Muntean. "SETDB1 Represses Hox Gene Expression and Suppresses Acute Myeloid Leukemia". Blood 132, Supplement 1 (29 de novembro de 2018): 1320. http://dx.doi.org/10.1182/blood-2018-99-117690.
Texto completo da fonteDong, Fang, Haitao Bai, Xiaofang Wang, Shanshan Zhang, Zhao Wang, Miner Xie, Sen Zhang et al. "Mouse acute leukemia develops independent of self-renewal and differentiation potentials in hematopoietic stem and progenitor cells". Blood Advances 3, n.º 3 (7 de fevereiro de 2019): 419–31. http://dx.doi.org/10.1182/bloodadvances.2018022400.
Texto completo da fonteChan, Lai N., Mark A. Murakami, Rebecca Caesar, Christian Hurtz, Kohei Kume, Teresa Sadras, Seyedmehdi Shojaee et al. "Signaling Input from Divergent Pathways Subverts Malignant B-Cell Transformation". Blood 134, Supplement_1 (13 de novembro de 2019): 3944. http://dx.doi.org/10.1182/blood-2019-130774.
Texto completo da fonteAivalioti, Maria M., Tushar D. Bhagat, Aditi Paranjpe, Boris Bartholdy, Kith Pradhan, Mario Pujato, Amit Verma e Britta Will. "PU.1-Dependent Enhancer Decommissioning Drives Transformation of Tet2 deficient Hematopoietic Stem and Progenitor Cells". Blood 136, Supplement 1 (5 de novembro de 2020): 40. http://dx.doi.org/10.1182/blood-2020-142070.
Texto completo da fonteHsieh, Mo-Ying, e Richard A. Van Etten. "Distinct Roles for the NF-κB Pathway In Myeloid and Lymphoid Transformation and Leukemogenesis by BCR-ABL." Blood 116, n.º 21 (19 de novembro de 2010): 1225. http://dx.doi.org/10.1182/blood.v116.21.1225.1225.
Texto completo da fonteHurtz, Christian, Cihangir Duy, Leandro Cerchietti, Eugene Park, Weimin Ci, Srividya Swaminathan, Soo-mi Kweon et al. "BCL6 Is Required for Leukemia-Initiation and Self-Renewal Signaling in Chronic Myeloid Leukemia." Blood 114, n.º 22 (20 de novembro de 2009): 2167. http://dx.doi.org/10.1182/blood.v114.22.2167.2167.
Texto completo da fonteOzpolat, Bulent, Ugur Akar, Magaly Barria e Gabriel Lopez-Berestein. "PKCδ Regulates Eukaryotic Initiation Factor eIF2α through PKR during Retinoic Acid-Induced Myeloid Cell Differentiation." Blood 108, n.º 11 (16 de novembro de 2006): 1928. http://dx.doi.org/10.1182/blood.v108.11.1928.1928.
Texto completo da fonteTrinh, Long Xuan, Young Kwang Chae, Preetesh Jain, Susan Lerner, Ohad Benjamini, Xuemei Wang e Michael J. Keating. "Second Cancers Affect the Clinical Outcomes of Patients with Chronic Lymphocytic Leukemia (CLL) Treated with Frontline FCR-Based Therapy." Blood 120, n.º 21 (16 de novembro de 2012): 2900. http://dx.doi.org/10.1182/blood.v120.21.2900.2900.
Texto completo da fonteXu, Dan, Xia Liu, Wen-Mei Yu, Howard J. Meyerson, Caiying Guo, Stanton L. Gerson e Cheng-Kui Qu. "Non–lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells". Journal of Experimental Medicine 208, n.º 10 (19 de setembro de 2011): 1977–88. http://dx.doi.org/10.1084/jem.20110450.
Texto completo da fonteSengupta, Amitava, Ashley M. Ficker, Susan K. Dunn, Malav Madhu e Jose A. Cancelas. "Bmi1 reprograms CML B-lymphoid progenitors to become B-ALL–initiating cells". Blood 119, n.º 2 (12 de janeiro de 2012): 494–502. http://dx.doi.org/10.1182/blood-2011-06-359232.
Texto completo da fonteOancea, Claudia, Brigitte Rüster, Jessica Roos, Afsar Ali Mian, Tatjana Micheilis, Hannelore Held, Anjali Dubey, Hubert Serve, Reinhard Henschler e Martin Ruthardt. "T(15;17)-PML/RAR-Induced Leukemogenesis: Long-Term Repopulating Hematopoietic Stem Cells as the Initial Target and More Mature Progenitors as the Potential Targets for Final Leukemic Transformation." Blood 114, n.º 22 (20 de novembro de 2009): 3980. http://dx.doi.org/10.1182/blood.v114.22.3980.3980.
Texto completo da fonteWang, Xiaoli, Cing Siang Hu, Joseph Tripodi, Vesna Najfeld, Bruce Petersen, Raajit K. Rampal, Noushin Farnoud, Christopher Famulare, John Mascarenhas e Ronald Hoffman. "Myeloproliferative Neoplasm (MPN) Blastic Transformation Occurs at the Level of Hematopoietic Stem Cells". Blood 132, Supplement 1 (29 de novembro de 2018): 101. http://dx.doi.org/10.1182/blood-2018-99-117348.
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