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Artigos de revistas sobre o tema "Iron Metabolism"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 7 de julho de 2024

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1

Conway, Deirdre, e Mark A. Henderson. "Iron metabolism". Anaesthesia & Intensive Care Medicine 23, n.º 2 (fevereiro de 2022): 123–25. http://dx.doi.org/10.1016/j.mpaic.2021.10.021.

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2

COUGHLAN, MICHAEL P. "Iron Metabolism". Biochemical Society Transactions 13, n.º 4 (1 de agosto de 1985): 803. http://dx.doi.org/10.1042/bst0130803.

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3

Aisen, Philip, Marianne Wessling-Resnick e Elizabeth A. Leibold. "Iron metabolism". Current Opinion in Chemical Biology 3, n.º 2 (abril de 1999): 200–206. http://dx.doi.org/10.1016/s1367-5931(99)80033-7.

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4

Conway, Deirdre, e Mark A. Henderson. "Iron metabolism". Anaesthesia & Intensive Care Medicine 20, n.º 3 (março de 2019): 175–77. http://dx.doi.org/10.1016/j.mpaic.2019.01.003.

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5

Badwing, TP. "Iron Metabolism". Biochemical Education 13, n.º 3 (julho de 1985): 150. http://dx.doi.org/10.1016/0307-4412(85)90229-8.

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6

Ponka, Prem. "Cellular iron metabolism". Kidney International 55 (março de 1999): S2—S11. http://dx.doi.org/10.1046/j.1523-1755.1999.055suppl.69002.x.

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7

Anderson, Gregory J., e David M. Frazer. "Hepatic Iron Metabolism". Seminars in Liver Disease 25, n.º 04 (2005): 420–32. http://dx.doi.org/10.1055/s-2005-923314.

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8

Rouault, Tracey A., e Sharon Cooperman. "Brain Iron Metabolism". Seminars in Pediatric Neurology 13, n.º 3 (setembro de 2006): 142–48. http://dx.doi.org/10.1016/j.spen.2006.08.002.

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9

Valerio, Luis G. "Mammalian Iron Metabolism". Toxicology Mechanisms and Methods 17, n.º 9 (janeiro de 2007): 497–517. http://dx.doi.org/10.1080/15376510701556690.

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10

Kohgo, Yutaka. "2. Iron Metabolism and Iron Overload." Nihon Naika Gakkai Zasshi 100, n.º 9 (2011): 2412–24. http://dx.doi.org/10.2169/naika.100.2412.

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11

Kohgo, Yutaka. "2. Iron Metabolism and Iron Overload". Nihon Naika Gakkai Zasshi 100, Suppl (2011): 46a—50a. http://dx.doi.org/10.2169/naika.100.46a.

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12

Asano, Masayuki, Kenshi Yamasaki, Takashi Yamauchi, Tadashi Terui e Setsuya Aiba. "Epidermal iron metabolism for iron salvage". Journal of Dermatological Science 87, n.º 2 (agosto de 2017): 101–9. http://dx.doi.org/10.1016/j.jdermsci.2017.04.003.

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13

Wang, Yafang, Lei Yu, Jian Ding e Yi Chen. "Iron Metabolism in Cancer". International Journal of Molecular Sciences 20, n.º 1 (27 de dezembro de 2018): 95. http://dx.doi.org/10.3390/ijms20010095.

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Demanded as an essential trace element that supports cell growth and basic functions, iron can be harmful and cancerogenic though. By exchanging between its different oxidized forms, iron overload induces free radical formation, lipid peroxidation, DNA, and protein damages, leading to carcinogenesis or ferroptosis. Iron also plays profound roles in modulating tumor microenvironment and metastasis, maintaining genomic stability and controlling epigenetics. in order to meet the high requirement of iron, neoplastic cells have remodeled iron metabolism pathways, including acquisition, storage, and efflux, which makes manipulating iron homeostasis a considerable approach for cancer therapy. Several iron chelators and iron oxide nanoparticles (IONPs) has recently been developed for cancer intervention and presented considerable effects. This review summarizes some latest findings about iron metabolism function and regulation mechanism in cancer and the application of iron chelators and IONPs in cancer diagnosis and therapy.

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14

Rouault, Tracey A. "Systemic iron metabolism: a review and implications for brain iron metabolism". Pediatric Neurology 25, n.º 2 (agosto de 2001): 130–37. http://dx.doi.org/10.1016/s0887-8994(01)00260-0.

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15

Słomka, Artur, Ewa Żekanowska, Katarzyna Piotrowska e Justyna Kwapisz. "Iron metabolism and maternal-fetal iron circulation". Postępy Higieny i Medycyny Doświadczalnej 66 (4 de janeiro de 2012): 876–87. http://dx.doi.org/10.5604/17322693.1019651.

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16

García, F., J. Sánchez e J. Planas. "IRon metabolism in iron-deficient male quail". Comparative Biochemistry and Physiology Part A: Physiology 87, n.º 4 (janeiro de 1987): 947–50. http://dx.doi.org/10.1016/0300-9629(87)90018-1.

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17

Wang, Jian, e Kostas Pantopoulos. "Regulation of cellular iron metabolism". Biochemical Journal 434, n.º 3 (24 de fevereiro de 2011): 365–81. http://dx.doi.org/10.1042/bj20101825.

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Iron is an essential but potentially hazardous biometal. Mammalian cells require sufficient amounts of iron to satisfy metabolic needs or to accomplish specialized functions. Iron is delivered to tissues by circulating transferrin, a transporter that captures iron released into the plasma mainly from intestinal enterocytes or reticuloendothelial macrophages. The binding of iron-laden transferrin to the cell-surface transferrin receptor 1 results in endocytosis and uptake of the metal cargo. Internalized iron is transported to mitochondria for the synthesis of haem or iron–sulfur clusters, which are integral parts of several metalloproteins, and excess iron is stored and detoxified in cytosolic ferritin. Iron metabolism is controlled at different levels and by diverse mechanisms. The present review summarizes basic concepts of iron transport, use and storage and focuses on the IRE (iron-responsive element)/IRP (iron-regulatory protein) system, a well known post-transcriptional regulatory circuit that not only maintains iron homoeostasis in various cell types, but also contributes to systemic iron balance.

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18

Forciniti, Stefania, Luana Greco, Fabio Grizzi, Alberto Malesci e Luigi Laghi. "Iron Metabolism in Cancer Progression". International Journal of Molecular Sciences 21, n.º 6 (24 de março de 2020): 2257. http://dx.doi.org/10.3390/ijms21062257.

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Iron is indispensable for cell metabolism of both normal and cancer cells. In the latter, several disruptions of its metabolism occur at the steps of tumor initiation, progression and metastasis. Noticeably, cancer cells require a large amount of iron, and exhibit a strong dependence on it for their proliferation. Numerous iron metabolism-related proteins and signaling pathways are altered by iron in malignancies, displaying the pivotal role of iron in cancer. Iron homeostasis is regulated at several levels, from absorption by enterocytes to recycling by macrophages and storage in hepatocytes. Mutations in HFE gene alter iron homeostasis leading to hereditary hemochromatosis and to an increased cancer risk because the accumulation of iron induces oxidative DNA damage and free radical activity. Additionally, the iron capability to modulate immune responses is pivotal in cancer progression. Macrophages show an iron release phenotype and potentially deliver iron to cancer cells, resulting in tumor promotion. Overall, alterations in iron metabolism are among the metabolic and immunological hallmarks of cancer, and further studies are required to dissect how perturbations of this element relate to tumor development and progression.

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19

Loreal, Olivier, Christelle Haziza-Pigeon, Marie-Berengere Troadec, Lenaick Detivaud, Bruno Turlin, Brice Courselaud, Guennadi Ilyin e Pierre Brissot. "Hepcidin in Iron Metabolism". Current Protein & Peptide Science 6, n.º 3 (1 de junho de 2005): 279–91. http://dx.doi.org/10.2174/1389203054065392.

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20

Harigae, Hideo. "Iron Metabolism -Recent Findings-". Nihon Naika Gakkai Zasshi 102, n.º 10 (2013): 2699–704. http://dx.doi.org/10.2169/naika.102.2699.

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21

AUSTONI, M. E., D. ZILIOTTO e E. ODEBLAD. "Thyroid and Iron Metabolism". Acta Medica Scandinavica 155, n.º 5 (24 de abril de 2009): 329–34. http://dx.doi.org/10.1111/j.0954-6820.1956.tb14381.x.

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22

Andrews, Nancy C. "Disorders of Iron Metabolism". New England Journal of Medicine 341, n.º 26 (23 de dezembro de 1999): 1986–95. http://dx.doi.org/10.1056/nejm199912233412607.

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23

Korman, Samuel. "IRON METABOLISM IN MAN*". Annals of the New York Academy of Sciences 88, n.º 2 (15 de dezembro de 2006): 460–73. http://dx.doi.org/10.1111/j.1749-6632.1960.tb20043.x.

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24

FEUILLEN, Y. M., e M. PLUMIER. "Iron Metabolism in Infants". Acta Paediatrica 41, n.º 2 (28 de junho de 2008): 138–44. http://dx.doi.org/10.1111/j.1651-2227.1952.tb17013.x.

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25

Cook, J. D. "Adaptation in iron metabolism". American Journal of Clinical Nutrition 51, n.º 2 (1 de fevereiro de 1990): 301–8. http://dx.doi.org/10.1093/ajcn/51.2.301.

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26

Schaefer, Benedikt, Maria Effenberger e Heinz Zoller. "Iron metabolism in transplantation". Transplant International 27, n.º 11 (20 de agosto de 2014): 1109–17. http://dx.doi.org/10.1111/tri.12374.

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27

Anderson, Gregory J., David M. Frazer e Gordon D. McLaren. "Iron absorption and metabolism". Current Opinion in Gastroenterology 25, n.º 2 (março de 2009): 129–35. http://dx.doi.org/10.1097/mog.0b013e32831ef1f7.

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28

Żekanowska, Ewa, Joanna Boinska, Paulina Giemza-Kucharska e Justyna Kwapisz. "Obesity and iron metabolism". BioTechnologia 2 (2011): 147–52. http://dx.doi.org/10.5114/bta.2011.46528.

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29

von Drygalski, Annette, e John W. Adamson. "Iron Metabolism in Man". Journal of Parenteral and Enteral Nutrition 37, n.º 5 (11 de setembro de 2012): 599–606. http://dx.doi.org/10.1177/0148607112459648.

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30

Papanikolaou, G., e K. Pantopoulos. "Iron metabolism and toxicity". Toxicology and Applied Pharmacology 202, n.º 2 (janeiro de 2005): 199–211. http://dx.doi.org/10.1016/j.taap.2004.06.021.

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31

Waldvogel-Abramowski, Sophie, Gérard Waeber, Christoph Gassner, Andreas Buser, Beat M. Frey, Bernard Favrat e Jean-Daniel Tissot. "Physiology of Iron Metabolism". Transfusion Medicine and Hemotherapy 41, n.º 3 (2014): 213–21. http://dx.doi.org/10.1159/000362888.

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32

Hagar, Ward, Elizabeth C. Theil e Elliott P. Vichinsky. "Diseases of iron metabolism". Pediatric Clinics of North America 49, n.º 5 (outubro de 2002): 893–909. http://dx.doi.org/10.1016/s0031-3955(02)00028-7.

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33

Anderson, Greg. "Iron metabolism and testing". Pathology 43 (2011): S20. http://dx.doi.org/10.1016/s0031-3025(16)33125-7.

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34

AUSTONI, M., D. ZILIOTTO, P. CARENZA e E. ODEBLAD. "Thyroid and Iron Metabolism". Acta Medica Scandinavica 162, n.º 1 (24 de abril de 2009): 1–7. http://dx.doi.org/10.1111/j.0954-6820.1958.tb01748.x.

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35

AUSTONI, M., P. CARENZA, D. ZILIOTTO e E. ODEBLAD. "Thyroid and Iron Metabolism." Acta Medica Scandinavica 164, n.º 1 (24 de abril de 2009): 19–22. http://dx.doi.org/10.1111/j.0954-6820.1959.tb00161.x.

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36

Nichol, Helen, John H. Law e Joy J. Winzerling. "Iron Metabolism in Insects". Annual Review of Entomology 47, n.º 1 (janeiro de 2002): 535–59. http://dx.doi.org/10.1146/annurev.ento.47.091201.145237.

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37

Bidlack, Wayne R. "Proteins of Iron Metabolism". Journal of the American College of Nutrition 21, n.º 3 (junho de 2002): 290–91. http://dx.doi.org/10.1080/07315724.2002.10719225.

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38

Fern??ndez-Ballart, Joan D. "Iron Metabolism during Pregnancy". Clinical Drug Investigation 19, Supplement 1 (2000): 9–19. http://dx.doi.org/10.2165/00044011-200019001-00002.

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39

Bezkorovainy, Anatoly, Eva Kot, Robin Miller-Catchpole, George Haloftis e Sergey Furmanov. "Iron metabolism in bifidobacteria". International Dairy Journal 6, n.º 10 (outubro de 1996): 905–19. http://dx.doi.org/10.1016/s0958-6946(96)00003-9.

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40

Swaiman, Kenneth F. "Iron metabolism in brain". Brain and Development 8, n.º 2 (janeiro de 1986): 101–2. http://dx.doi.org/10.1016/s0387-7604(86)80028-6.

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41

Pietrangelo, Antonello. "Proteins of iron metabolism". Gastroenterology 125, n.º 6 (dezembro de 2003): 1906. http://dx.doi.org/10.1053/j.gastro.2003.08.039.

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42

Arredondo, Miguel, e Marco T. Núñez. "Iron and copper metabolism". Molecular Aspects of Medicine 26, n.º 4-5 (agosto de 2005): 313–27. http://dx.doi.org/10.1016/j.mam.2005.07.010.

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43

Fleming, Robert E., e Robert S. Britton. "Iron Metabolism: Clinical Implications". Transfusion Alternatives in Transfusion Medicine 8 (abril de 2006): 43–44. http://dx.doi.org/10.1111/j.1778-428x.2006.tb00215.x.

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44

Andrews, Nancy C. "Iron metabolism and absorption". Reviews in Clinical and Experimental Hematology 4, n.º 4 (dezembro de 2000): 283–301. http://dx.doi.org/10.1046/j.1468-0734.2000.00021.x.

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45

Ganz, Tomas. "Hepcidin in iron metabolism". Current Opinion in Hematology 11, n.º 4 (julho de 2004): 251–54. http://dx.doi.org/10.1097/00062752-200407000-00004.

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46

Ratledge, Colin. "Iron Metabolism and Infection". Food and Nutrition Bulletin 28, n.º 4_suppl4 (dezembro de 2007): S515—S523. http://dx.doi.org/10.1177/15648265070284s405.

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47

Prentice, Andrew M., Hala Ghattas, Conor Doherty e Sharon E. Cox. "Iron Metabolism and Malaria". Food and Nutrition Bulletin 28, n.º 4_suppl4 (dezembro de 2007): S524—S539. http://dx.doi.org/10.1177/15648265070284s406.

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48

Camaschella, Clara. "BMP6 orchestrates iron metabolism". Nature Genetics 41, n.º 4 (abril de 2009): 386–88. http://dx.doi.org/10.1038/ng0409-386.

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49

Soares, Miguel P., e Iqbal Hamza. "Macrophages and Iron Metabolism". Immunity 44, n.º 3 (março de 2016): 492–504. http://dx.doi.org/10.1016/j.immuni.2016.02.016.

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50

Powers, Jacquelyn M., e George R. Buchanan. "Disorders of Iron Metabolism". Hematology/Oncology Clinics of North America 33, n.º 3 (junho de 2019): 393–408. http://dx.doi.org/10.1016/j.hoc.2019.01.006.

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