Bibliografias temáticas / Immunohistochemistry

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Literatura científica selecionada sobre o tema "Immunohistochemistry"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 25 de julho de 2025

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Artigos de revistas sobre o assunto "Immunohistochemistry"

B. Ingle, Sachin. "Immunohistochemistry." International Journal of Current Research and Review 10, no. 11 (2018): 0–1. http://dx.doi.org/10.31782/ijcrr.2018.10115.

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Taylor, Clive R. "Immunohistochemistry." Applied Immunohistochemistry & Molecular Morphology 27, no. 5 (2019): 325–26. http://dx.doi.org/10.1097/pai.0000000000000770.

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Fuchigami, Hirobumi, Kazunobu Ohnuki, Toshihiro Suzuki, and Kazumasa Takenouchi. "Immunohistochemistry." Drug Delivery System 39, no. 3 (2024): 218–21. http://dx.doi.org/10.2745/dds.39.218.

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Mani, Haresh, and Dani S. Zander. "Immunohistochemistry." Chest 142, no. 5 (2012): 1324–33. http://dx.doi.org/10.1378/chest.12-0123.

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&NA;. "Immunohistochemistry." Pathology 22 (1990): 9–10. http://dx.doi.org/10.3109/00313029009060103.

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Aryal, G. "Immunohistochemistry." Journal of Pathology of Nepal 5, no. 10 (2015): I. http://dx.doi.org/10.3126/jpn.v5i10.15660.

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Immunohistochemistry (IHC) or immunocytochemistry is a method of localizing specific antigen in tissue or cells based on antigen antibody reaction. IHC is the way of validating morphological findings. It helps in tumor diagnosis and classification, identify prognostic and predictive markers. IHC has a long history that dates back more than 70 years, when Coons1 first developed immunofluroscence technique to detect corresponding antigen in frozen tissue section. At oxford, Taylor and Burns2 developed the first successful demonstration of antigens in routinely processed formalin fixed paraffin-e

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Dabbs, David J. "Immunohistochemistry." Pathology Case Reviews 4, no. 6 (1999): 229. http://dx.doi.org/10.1097/00132583-199911000-00001.

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Mani, Haresh, and Dani S. Zander. "Immunohistochemistry." Chest 142, no. 5 (2012): 1316–23. http://dx.doi.org/10.1378/chest.11-3327.

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Mazroa, Shireen A. "Immunohistochemistry." Egyptian Journal of Histology 35, no. 2 (2012): 191–97. http://dx.doi.org/10.1097/01.ehx.0000414291.44156.ef.

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Wittekind, Christian, and Andrea Tannapfel. "Immunohistochemistry." Digestion 58, no. 1 (1997): 79–81. http://dx.doi.org/10.1159/000201534.

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Teses / dissertações sobre o assunto "Immunohistochemistry"

King, George. "Studies of amplification methods in immunohistochemistry." Thesis, University of Aberdeen, 2001. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU537963.

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The aim of this project was to compare and contrast the results of three related methodologies which are of particular relevance or potential within our department -. a manually performed streptAvidin Biotin Complex (sABC/ HRP) method which for many years has served as our 'standard' immunocytochemical method; an integrated semi-automated systems from DAKO based on the TechMate 500 immunostainer and the ChemMate reagent package;. a manually performed tyramide amplification method regarded as amongst the most sensitive immunocytochemical method currently available. Antigen retrieval investigati

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Lam, Sing-chi, and 藍承志. "A HRCT and immunohistochemistry study on bronchiectasis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B30402499.

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Shu, Jie. "Immunohistochemistry image analysis : protein, nuclei and gland." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/27616/.

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This thesis focus on the analysis of digitized microscopic image, especially on IHC stained colour images. The corresponding contributions focused on the automatic detection of stain colour and glands, the segmentation and quantification of cell nuclei, the analysis of liver cirrhosis and the development of a semi-automatic toolbox. Colour is the most important feature in the analysis of immunostained images. We developed a statistical colour detection model for stain colour detection based on the histograms of collected colour pixels. This is acting on the approach "what you see is what you g

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Koria, Muntaha. "Identification of PHPT1 in mouse tissues by immunohistochemistry." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7745.

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<p>Although it has been estimated that protein histidine phosphorylation account for about 6 % of the protein phosphorylation in eukaryotic cells; the knowledge of histidine phosphorylation and dephosphorylation is still limited. Lately, studies have appeared of a mammalian 14-kDa phospho- histidine phosphatase, also named protein histidine phosphatase and molecular cloning have provided some information of its physiological role. The object of the present study was to detect the protein expression of protein histidine phosphatase, PHPT1, in mouse tissue, by using immunohistochemistry. Tissue

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Sundara, Rajan Sreekumar. "Investigating male breast cancer using transcriptomics and immunohistochemistry." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/15847/.

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Background: The rare nature of male breast cancer (MBC) has led to its management being guided by the extensive research conducted in the field of female breast cancer (FBC). The aim of this study was to evaluate MBC at both protein and molecular level to improve understanding of its pathology. Methodology: Immunohistochemistry analysis was performed in MBC (n=428) TMAs for 18 biomarkers (ERα, ERβ1, ERβ2, ERβ5, Total PR, AR, CK5/6, CK14, CK18, CK19, p53, Bcl-2, Her2, E-cadherin, Ki67, Survivin, Prolactin and FOXA1). The manual scoring of ERα and Ki67 was correlated with a fully automated immun

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Café, Marçal Valéria. "Pathology and immunohistochemistry of Cheetah (Acinonyx jubatus) myelopathy /." [S.l.] : [s.n.], 2006. http://www.stub.ch/index.php?p=1&i=645.

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Rozell, Björn. "Immunohistochemical studies of the thioredoxin system." Göteborg : Dept. of Histology, University of Göteborg, 1987. http://catalog.hathitrust.org/api/volumes/oclc/17242526.html.

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Kolivras, Athanassios. "Immunohistochemistry in the histopathological diagnosis of primary scalp alopecia." Doctoral thesis, Universite Libre de Bruxelles, 2016. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/238160.

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Primary scalp alopecia is classically divided into cicatricial (scarring) and non-cicatricial (non-scarring). Challenging cases are assessed with a scalp biopsy. The use of both horizontal and vertical sections (HoVert sections) has dramatically improved the accuracy of histopathological diagnosis. In this work, we have used immunostaining to address diagnostic difficulties, which persist despite all currently available tools. We performed an immunostain panel (CD3, CD4, CD8 and CD20) in order to distinguish pattern hair loss from alopecia aerate in cases which do not have the usual peribulbar

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Holtzhausen, Wendy. "Diuretic factors controlling beetle malphighian tubules fluid secretion and immunohistochemistry /." Pretoria : [s.n.], 2006. http://upetd.up.ac.za/thesis/available/etd-07182007-164904.

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Fung, Hau-yin Kevin. "Detection of SARS-CoV in lung tissues by immunohistochemistry and in-situ hybridization /." View the Table of Contents & Abstract, 2005. http://sunzi.lib.hku.hk/hkuto/record/B32020624.

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Livros sobre o assunto "Immunohistochemistry"

Kalyuzhny, Alexander E. Immunohistochemistry. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30893-7.

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Simon, Renshaw, ed. Immunohistochemistry. Scion, 2007.

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Chu, Peiguo. Modern immunohistochemistry. Cambridge University Press, 2009.

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C, Cuello A., ed. Immunohistochemistry II. Wiley, 1993.

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Del Valle, Luis, ed. Immunohistochemistry and Immunocytochemistry. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1948-3.

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Kalyuzhny, Alexander E., ed. Signal Transduction Immunohistochemistry. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6759-9.

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Kalyuzhny, Alexander E., ed. Signal Transduction Immunohistochemistry. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-024-9.

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Kalyuzhny, Alexander E., ed. Signal Transduction Immunohistochemistry. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2811-9.

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A, DeLellis Ronald, ed. Advances in immunohistochemistry. Raven Press, 1988.

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Lin, Fan, Jeffrey W. Prichard, Haiyan Liu, and Myra L. Wilkerson, eds. Handbook of Practical Immunohistochemistry. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-83328-2.

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Capítulos de livros sobre o assunto "Immunohistochemistry"

Ramos-Vara, José A., and Luke B. Borst. "Immunohistochemistry." In Tumors in Domestic Animals. John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781119181200.ch3.

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Clausen, P. P., M. Møller, B. van Deurs, and O. W. Petersen. "Immunohistochemistry." In Theory and Strategy in Histochemistry. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-73742-8_26.

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Chiaravalli, Anna Maria. "Immunohistochemistry." In Encyclopedia of Pathology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-28845-1_5085-1.

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Kigawa, Junzo, Tsunehisa Kaku, Toru Sugiyama, and Steven G. Silverberg. "Immunohistochemistry." In Atlas of Clear Cell Carcinoma of the Ovary. Springer Japan, 2015. http://dx.doi.org/10.1007/978-4-431-55438-7_6.

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Azumi, Norio, and Bernard Czernobilsky. "Immunohistochemistry." In Blaustein’s Pathology of the Female Genital Tract. Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4757-3889-6_26.

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Taylor, Clive R., and Richard J. Cote. "Immunohistochemistry." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_2995-2.

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Baron, Jeffrey, Jeffrey M. Voigt, Thomas T. Kawabata, and Jan A. Redick. "Immunohistochemistry." In Regulation of Hepatic Metabolism. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5041-5_4.

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Davis, Barbara J. "Immunohistochemistry." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_1594.

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Carbone, Giancarlo. "Immunohistochemistry." In Antibody Usage in the Lab. Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-662-03942-7_6.

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Chiaravalli, Anna Maria. "Immunohistochemistry." In Endocrine Pathology. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-62345-6_5085.

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Trabalhos de conferências sobre o assunto "Immunohistochemistry"

Qiu, Fanhao, Yangyang Zhang, Xiaoguang Guo, and Zhengxia Wang. "Weakly Supervised Virtual Immunohistochemistry Staining via Schrödinger Bridge Method." In 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2024. https://doi.org/10.1109/bibm62325.2024.10822509.

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Kang, Dongkyun, Yongjun Kim, Jingwei Zhao, et al. "Scattering-based light sheet microscopy images of anal lesions with challenging morphological features." In Bio-Optics: Design and Application. Optica Publishing Group, 2025. https://doi.org/10.1364/boda.2025.dm1a.2.

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We evaluated cellular morphological features visualized in scattering-based light sheet microscopy images of anal biopsies that were later submitted for p16 immunohistochemistry staining due to inconclusive findings from H&E images.

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Mickert, Matthias, Magnus Helgstrand, Sanathana Konugolu Venkata Sekar, et al. "Increasing Objectivity in Quantitative Analysis in Immune-Histochemistry Biomarker Mapping using Upconverting Nanoparticles." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2025. https://doi.org/10.1364/omp.2025.otu1e.2.

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Today immunohistochemistry (IHC) stains molecular biomarkers for treatment stratification. IHC can become increasingly objective by improving sensitivity, quantification and multiplexing capabilities. We use upconverting nanoparticles to achieve this, potentially leading to improved treatment outcomes.

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Li, Jiahan, Jiuyang Dong, Shenjin Huang, et al. "Virtual Immunohistochemistry Staining for Histological Images Assisted by Weakly-supervised Learning." In 2024 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR). IEEE, 2024. http://dx.doi.org/10.1109/cvpr52733.2024.01070.

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Perrin, Romain, Aurélie Leborgne, Nicolas Passat, Benoît Naegel, and Cédric Wemmert. "Multi-Scale Component-Trees for Enhanced Representation in Multiplex Immunohistochemistry Imaging." In 2024 IEEE International Symposium on Biomedical Imaging (ISBI). IEEE, 2024. http://dx.doi.org/10.1109/isbi56570.2024.10635272.

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Li, Wentao, Xingde Luo, Ziqi Yang, Xiaofang Jia, and Zhongyu Li. "A Foundation Model for Cell Segmentation from Immunohistochemistry: A Pilot Study." In 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI). IEEE, 2025. https://doi.org/10.1109/isbi60581.2025.10980902.

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Long, Xi, Tianyang Wang, Yanjia Kan, et al. "Pseudo Training Data Generation for Unsupervised Cell Membrane Segmentation in Immunohistochemistry Images." In 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2024. https://doi.org/10.1109/bibm62325.2024.10822664.

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Zabihollahy, Fatemeh, Xiaotian Yuan, Maxim Mohareb, et al. "Automated quantification of TP53 using digital immunohistochemistry for acute myeloid leukemia prognosis." In Digital and Computational Pathology, edited by John E. Tomaszewski and Aaron D. Ward. SPIE, 2025. https://doi.org/10.1117/12.3046351.

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Chen, Pingjun, Maria E. Salvatierra, Alejandra Serrano, et al. "Optimizing Cell Recognition in Sarcoma Multiplex Immunohistochemistry Images via Pre-Training Strategies." In 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI). IEEE, 2025. https://doi.org/10.1109/isbi60581.2025.10980737.

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Kawai, Masataka. "Exclusive loss in segmentation for the virtual multiplex immunohistochemistry using multiple singleplex masks." In Digital and Computational Pathology, edited by John E. Tomaszewski and Aaron D. Ward. SPIE, 2025. https://doi.org/10.1117/12.3044651.

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Relatórios de organizações sobre o assunto "Immunohistochemistry"

มณีศรี เลอกรองด์, ศุภางค์. โครงการวิจัยผลของการได้รับยาพาราเซตตามอลอย่างเรื้อรังต่อการเปลี่ยนแปลงของเซลล์บุผนังหลอดเลือดสมอง : โครงสร้างในระดับจุลทรรศน์อิเลคตรอน และการหลั่งสารกระตุ้นการอักเสบ : รายงานการวิจัยฉบับสมบูรณ์. จุฬาลงกรณ์มหาวิทยาลัย, 2010. https://doi.org/10.58837/chula.res.2010.19.

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การศึกษาครั้งนี้มีจุดประสงค์เพื่อศึกษาผลของการได้รับยาพาราเซลตามอลแบบต่อเนื่องต่อการเปลี่ยนแปลงหลอดเลือดสมองและการแสดงออกของสารกระตุ้นการอักเสบ TNF alpha และIL-1 ในสมอง โดยแบ่งการทดลองออกเป็นกลุ่มควบคุม และกลุ่มที่ได้รับยาพาราเซตตามอล โดยหนูในกลุ่มที่ได้รับพาราเซตตามอลได้รับการฉีดพาราเซตตามอล 200 มิลลิกรัมต่อกิโลกรัมน้ำหนักตัวต่อเนื่องทุกวันเป็นระยะเวลา 30 วัน ในขณะที่กลุ่มควบคุมได้รับ NSS แทน ทั้งสองกลุ่มทดลองแบ่งย่อยเป็นกลุ่มที่ได้รับและไม่ได้รับการกระตุ้นให้เกิดปรากฎการณ์คอร์ติคัลสเปรดดิ้งคีเพรสชั่น โดยปรากฎการณ์คอร์ติคัลสเปรดดิ้งดีเพรสชั่นนั้นถูกเหนี่ยวนำโดยการวางผลึกโพแทสเซียมคลอไรด์ขนาด

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Pleva, Christina M., Tracey A. Hamilton, John P. Petrali, and Robert K. Kan. Determining Optimal Microwave Antigen Retrieval Conditions for Microtubule-Associated Protein 2 Immunohistochemistry in the Guinea Pig Brain. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada417833.

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แอกทอง, สิทธิพร, та อทิตยา แก้วเสมา. การพัฒนาวิธีการรักษาการบาดเจ็บของเส้นประสาทโดยการเปลี่ยนแปลงระดับการกระตุ้นของ MAPKs : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2011. https://doi.org/10.58837/chula.res.2011.21.

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การบาดเจ็บของเส้นประสาทเป็นสาเหตุที่สำคัญของภาวะทุพพลภาพเนื่องจากการตายของเซลล์ประสาทและเซลล์ค้ำจุน มีหลักฐานบ่งชี้ว่า p38 MAPK น่าจะมีบทบาทสำคัญในกระบวนการดังกล่าว การศึกษานี้มีจุดประสงค์เพื่อดูการเปลี่ยนแปลงระดับการทำงานของ p38 ในปมประสาทไขสันหลังและเส้นประสาทหลังการบาดเจ็บของเส้นประสาทและทดสอบว่า p38 เกี่ยวข้องกับกระบวนการ apoptosis ในโครงสร้างเหล่านี้หรือไม่ โดยทำให้เกิดการบาดเจ็บของเส้นประสาท sciatic แบบตัดขาด (transection) ในหนู จากนั้นเมื่อครบ 2 สัปดาห์นำเนื้อเยื่อมาศึกษาระดับ p38 และโปรตีนที่เกี่ยวข้องกับ apoptosis หนูอีกส่วนถูกแบ่งเป็นกลุ่มที่ได้รับ p38 inhibitor คือ SB203580 ขนาด 200

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ปิยะธีรธิติวรกุล, สมเกียรติ, та ศิริรัตน์ เร่งพิพัฒน์. แลกติกแอซิดแบคทีเรียที่ใช้เป็นโพรไบโอติกสำหรับปลากะพงขาว Lates calcarifer : รายงานฉบับสมบูรณ์. ศูนย์เชี่ยวชาญเฉพาะทางด้านเทคโนโลยีชีวภาพทางทะเล ภาควิชาวิทยาศาสตร์ทางทะเล คณะวิทยาศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2005. https://doi.org/10.58837/chula.res.2005.76.

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การแยกแลกติกแอซิดแบคทีเรียจากทางเดินอาหารของปลากะพงขาว เพื่อคัดเลือกแบคทีเรียที่มีสมบัติเป็นโพรไบโอติก ด้วยเทคนิค well agar diffusion ผลพบว่า มี 5 ไอโซเลต (กำหนดให้เป็น LAB-1 - LAB-5) ที่สามารถยับยั้งการเจริญของ Aeromonas hydrophila แบคทีเรียก่อโรคในปลาได้ ผลการวิเคราะห์ปริมาณองค์ประกอบในอาหารผสมแบบเปียก พบว่า ปริมาณสารอาหารต่างๆ ในอาหารมีเพียงพอกับความต้องการของปลากะพงขาว ยกเว้นปริมาณไขมันที่ต่ำเกินไป ความเข้มข้นของ A. hydrophila ที่ทำให้ปลาตาย 50% (LC50) หลังจากที่ปลาได้รับเชื้อแล้ว 72 ชั่วโมง มีค่าเท่ากับ 7.76 log10 เซลล์/มล. และที่ 96 และ 120 ชั่วโมง มีค่าเท่ากับ 7.47 และ 7.26 log10 เซลล์/

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Burke, Allen P. Detection and Clinicopathologic Correlation of Human Immunodeficiency Virus (HIV-1) Nucleic Acids and Antigens in Reticuloendothelial and Central Nervous System Tissues, by Immunohistochemistry, in situ Hybridization, and Polymerase Chain Reaction. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada259307.

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Patumraj, Suthiluk, and Sheepsumon Viboolvorakul. Protective effects of exercise training against vascular and neuronal dysfunction in aging brain. Department of Physiology, Faculty of Medicine, Chulalongkorn University, 2019. https://doi.org/10.58837/chula.res.2019.11.

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During advancing age, reduction of microvessels in the brain contributes insufficiency tissue perfusion. Mounting evidence indicates that microvascular deterioration in aged brain relates to oxidative stress. Nuclear factor erythroid-related factor 2 (Nrf2) plays an important role in cellular antioxidant defense. Regular physical exercise is well known to have beneficial effect to brain health, including promoted blood flow and augmented angiogenesis, in aging individuals. However, the underlying mechanism of regular physical exercise in improvement of brain microvascular density during advanc

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Tummaruk, Padet. Impact of PRRS virus infection in the replacement gilts on number and development of follicles in the ovarian tissues. Chulalongkorn University, 2015. https://doi.org/10.58837/chula.res.2015.81.

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Replacement gilts are a major source of introducing the porcine reproductive and respiratory syndrome (PRRS) virus into the swine breeding herd. The objective of the present study was to determine the prevalence of PRRS virus antigen by detection in the ovary of gilts culled due to reproductive disturbances. Ovarian tissues were collected from 100 Landrace x Yorkshire crossbred slaughtered gilts in Thailand. PRRS virus antigen in the ovarian tissues were detected by using immunohistochemistry. On average, the gilts were culled at 277 days of age at a body weight of 148 kg. Of these gilts, 75 h

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Suriyaphol, Gunnaporn. Study the gene expression of E-cadherin, syndecan1, matrix metalloproteinases-2, -7, -9, -14 and tissue inhibitors of metalloproteinases-1 and -2 in canine oral melanoma. Chulalongkorn University, 2015. https://doi.org/10.58837/chula.res.2015.80.

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The objectives of this study were to 1.) select the suitable reference genes for quantitative real-time polymerse chain reaction in the most common canine oral cancers: oral melanoma (OM) and oral squamous cell carcinoma (OSCC), 2.) study the gene expression of E-cadherin (CDH1), syndecan 1 (SDC1), matrix metalloproteinases-2, -7, -9, -14 (MMP2, MMP7, MMP9, MMP14) and tissue inhibitors of metalloproteinases-1 and -2 (TIMP1, TIMP2) in canine OM at the mRNA level and study the CDH1, SDC1 and Ki-67 protein expression by immunohistochemistry, and 3.) study the association of gene expression and th

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Funkenstein, Bruria, and Cunming Duan. GH-IGF Axis in Sparus aurata: Possible Applications to Genetic Selection. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7580665.bard.

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Many factors affect growth rate in fish: environmental, nutritional, genetics and endogenous (physiological) factors. Endogenous control of growth is very complex and many hormone systems are involved. Nevertheless, it is well accepted that growth hormone (GH) plays a major role in stimulating somatic growth. Although it is now clear that most, if not all, components of the GH-IGF axis exist in fish, we are still far from understanding how fish grow. In our project we used as the experimental system a marine fish, the gilthead sea bream (Sparus aurata), which inhabits lagoons along the Mediter

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Fields, Michael J., Mordechai Shemesh, and Anna-Riitta Fuchs. Significance of Oxytocin and Oxytocin Receptors in Bovine Pregnancy. United States Department of Agriculture, 1994. http://dx.doi.org/10.32747/1994.7568790.bard.

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Oxytocin has multiple actions in bovine reproductive tract and it was our purpose to determine the nature of these actions and their significance for the physiology of bovine reproduction. The bovine oxytocin receptors (OTR) gene was cloned and its expression studied during the cycle and pregnancy. OTR mRNA changed in parallel with OTR with control occurring mainly at the transcriptional level. However, the endocrine regulation of OTR were found in endometrium and cervical mucosa at estrus and at parturition. In both tissues OTR were suppressed in the luteal phase and early pregnancy. Whereas

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