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Artigos de revistas sobre o tema "I-464"

Autor: Grafiati

Publicado: 29 de julho de 2024

Última modificação: 31 de julho de 2024

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1

Stocker, Sean D., Alan F. Sved e Michael C. Andresen. "Missing pieces of the Piezo1/Piezo2 baroreceptor hypothesis: an autonomic perspective". Journal of Neurophysiology 122, n.º 3 (1 de setembro de 2019): 1207–12. http://dx.doi.org/10.1152/jn.00315.2019.

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Baroreceptors play a pivotal role in the regulation of blood pressure through moment to moment sensing of arterial blood pressure and providing information to the central nervous system to make autonomic adjustments to maintain appropriate tissue perfusion. A recent publication by Zeng and colleagues (Zeng WZ, Marshall KL, Min S, Daou I, Chapleau MW, Abboud FM, Liberles SD, Science 362: 464–467, 2018) suggests the mechanosensitive ion channels Piezo1 and Piezo2 represent the cellular mechanism by which baroreceptor nerve endings sense changes in arterial blood pressure. However, before Piezo1 and Piezo2 are accepted as the sensor of baroreceptors, the question must be asked of what criteria are necessary to establish this and how well the report of Zeng and colleagues (Zeng WZ, Marshall KL, Min S, Daou I, Chapleau MW, Abboud FM, Liberles SD, Science 362: 464–467, 2018) satisfies these criteria. We briefly review baroreceptor function, outline criteria that a putative neuronal sensor of blood pressure must satisfy, and discuss whether the recent findings of Zeng and colleagues suitably meet these criteria. Despite the provocative hypothesis, there are significant concerns regarding the evidence supporting a role of Piezo1/Piezo2 in arterial baroreceptor function.

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da Empoli, Domenico. "Magnani, I., Dibattito tra economisti italiani difine Ottocento". Journal of Public Finance and Public Choice 21, n.º 1 (1 de abril de 2003): 84–87. http://dx.doi.org/10.1332/251569203x15665366543863.

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da Empoli, Domenico. "Monti, A. - Briganti, A. (eds), 2002, Rapporto sull’istruzione universitaria in Italia – I costi e i rischi delta riforma",. Journal of Public Finance and Public Choice 20, n.º 1 (1 de abril de 2002): 77–79. http://dx.doi.org/10.1332/251569202x15665366114860.

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BERETTA, MARCO. "OLIVIER BLOCH, Matière à histoires, Paris, Vrin, 1997, 464 pp. (ISBN 0249-7980), 340 ff." Nuncius 14, n.º 2 (1 de janeiro de 1999): 677–79. http://dx.doi.org/10.1163/221058799x00142.

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Martínez García, Sebastián, e Tomás Silva Sánchez. "Apuntes crítico textuales a los Cynegetica de Opiano de Apamea". Emerita 88, n.º 1 (2 de junho de 2020): 143. http://dx.doi.org/10.3989/emerita.2020.08.1928.

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Rådö, Göran. "Ett gott liv inom planetens gränser är möjligt. Två böcker pekar på lösningar". Socialmedicinsk tidskrift 100, n.º 2 (20 de junho de 2023): 410–11. http://dx.doi.org/10.62607/smt.v100i2.22237.

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För att bidra till att sprida nödvändig kunskap har Greta Thunberg i Klimatboken samlat texter från ett hundratal forskare, experter, aktivister och författare som belyser klimat- , ekologi - och hållbarhetskrisen ur ett helhetsperspektiv. I närmare 20 egna kommentarer tryckta på papper i avvikande färg formulerar hon egna slutsatser och uppmaningar med rubriker som " Vi måste göra något som verkar omöjligt " och " Hopp är något vi måste förtjäna". Boken är på 464 sidor och har givits ut samtidigt i en rad olika länder inför klimattoppmötet i Egypten i november 2022.

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Hernàndez i Garcia, Xavier. "Montserrat Corretger & Oriol Teixell (eds.), «Literatura catalana contemporània: patrimoni i identitat», Barcelona, Institut d’Estudis Catalans / Universitat Rovira i Virgili, 2019, 251 p. // Josep Camps Arbós & Maria Dasca (eds.), «La narrativa catalana al segle XXI, balanç crític», Barcelona, Institut d’Estudis Catalans, 2019, 139 p." Caplletra. Revista Internacional de Filologia, n.º 71 (6 de outubro de 2021): 271. http://dx.doi.org/10.7203/caplletra.71.21043.

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Ressenyes sobre els llibres següents: Montserrat Corretger & Oriol Teixell (eds.), Literatura catalana contemporània: patrimoni i identitat, Barcelona, Institut d’Estudis Catalans / Universitat Rovira i Virgili, 2019, 251 p., ISBN: 978-84-9965-456-0. Josep Camps Arbós & Maria Dasca (eds.), La narrativa catalana al segle xxi, balanç crític, Barcelona, Institut d’Estudis Catalans, 2019, 139 p., ISBN: 978-84-9965-464-5.

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Rödel, Michael. "Heiko Hausendorf. 2020. Deutschstunde(n). Erkundungen zur Lesbarkeit der Literatur. Stuttgart: Kröner Verlag. 464 S." Zeitschrift für Rezensionen zur germanistischen Sprachwissenschaft 13, n.º 1-2 (1 de dezembro de 2021): 76–80. http://dx.doi.org/10.1515/zrs-2021-2071.

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Campos, Luis A. "Genetic engineering’s contested ethics As Gods Matthew Cobb Basic Books, 2022. 464 pp." Science 378, n.º 6620 (11 de novembro de 2022): 607. http://dx.doi.org/10.1126/science.ade5848.

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Yanai, Itai, e Martin J. Lercher. "Thinking about science I’ve Been Thinking Daniel C. Dennett Norton, 2023. 464 pp." Science 382, n.º 6671 (10 de novembro de 2023): 653. http://dx.doi.org/10.1126/science.adk5070.

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Vieta, Eduard, Ross A. Baker, Jessica J. Madera, Peter Zhang, Pedro Such, Maxine Chen e Joseph Calabrese. "47 Sustained Functional Recovery and Symptom Remission After Maintenance Treatment with Aripiprazole Once-Monthly for Patients with Bipolar I Disorder". CNS Spectrums 24, n.º 1 (fevereiro de 2019): 201–2. http://dx.doi.org/10.1017/s1092852919000403.

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AbstractStudy ObjectivesTo report functional recovery, symptomatic remission, and sustained symptomatic remission rates after treatment with aripiprazole once-monthly 400mg (AOM 400) administered every 4weeks for up to 52weeks as maintenance treatment in a mixed cohort of AOM 400 naïve (de novo) and experienced adults (rollover) with bipolar I disorder (BP-I).MethodThis open-label study (NCT01710709) enrolled de novo patients with a diagnosis of BP-I and ≥1 previous manic or mixed episode and rollover patients who completed a randomized, double-blind, placebo-controlled study assessing the efficacy and safety of AOM 400 (NCT01567527). Efficacy was assessed by mean changes from baseline in Young-Mania Rating Scale (YMRS), Montgomery-Asberg Depressive Rating Scale (MADRS), and Clinical Global Impression- Bipolar Version-Severity of Illness (CGI-BP-S) scores. Sustained functional recovery was defined as a total score of ≤11 on the Functioning Assessment Short Test (FAST) for ≥8 consecutive weeks. Remission was defined as YMRS and MADRS total scores ≤12, and sustained remission was defined as meeting criteria for remission for 8 consecutive weeks. The study included a screening phase (6weeks) for de novo patients, an oral aripiprazole conversion phase (4–6weeks), an oral stabilization phase (4–12weeks), and an AOM 400 maintenance phase (up to 52weeks). Rollover patients entered directly into the AOM 400 maintenance phase.ResultsA total of 464 subjects entered the maintenance phase and 63% (291/464) completed the trial. Of patients entering the maintenance phase, 379 (82%) were de novo and 85 (18%) were rollover. The most frequent reasons for discontinuation were withdrawal of consent (11%) and adverse events (AEs) (10%). Weight increase (1.5%, 7/464) and BP-I (0.9%, 4/464) were the most common reasons for discontinuation due to AEs. Improvements in mean YMRS, MADRS, CGI-BP-S, and FAST scores achieved in previous phases were maintained over 52weeks. Treatment-emergent AEs experienced by >10% of the patients were akathisia (14.7%), weight increased (13.4%), nasopharyngitis (12.1%), and insomnia (11.0%). A high proportion of de novo patients met the criteria for symptomatic remission (87.2%, 328/376) and sustained remission (77%, 292/379) by last visit. Rollover patients’ remission rate remained stable (98.8%, 84/85) by last visit. Of the rollover patients, 35/85 (43%) and 35/116 (36%) of de novo subjects met the criteria for sustained functional recovery after study completion.ConclusionsPatients treated with AOM 400 maintained symptomatic and functional stability for up to 52weeks. Importantly, more than one-third of patients achieved sustained functional recovery using a strict criterion. Overall, AOM 400 was safe and well tolerated in patients with BP-I. Results support AOM 400 as a viable once-monthlyoption for maintenance treatment of BP-I.These data were previously presented at the 31st ECNP Congress, 2018, Barcelona,Spain.Funding Acknowledgements: The study was supported by Otsuka Pharmaceutical Development & Commercialization, Inc.

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Aufdembrinke, B. "Abecarnil, a new beta-carboline, in the treatment of anxiety disorders". British Journal of Psychiatry 173, S34 (julho de 1998): 55–63. http://dx.doi.org/10.1192/s0007125000293537.

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Background Abecarnil, a novel anxiolytic beta-carboline, was investigated in five four-week double-blind, European multicentre studies. Overall, 451 patients with generalised anxiety disorder were randomised to abecarnil, 461 to placebo and 464 to active controls.Method Data includes inferential statistics based on individual studies and descriptive analysis of 323 patients in open-label abecarnil longterm continuation up to 52 weeks.Results Abecarnil was safe, the most frequent adverse event being drowsiness. Onset of effect was at week I. At week 4 the Hamilton Anxiety Scale score had improved by 12–13 points on average. Due to notably large and variable placebo effects abecarnil was not consistently superior to placebo. No rebound or withdrawal symptoms were observed after fast-tapered discontinuation. Safety, extent of efficacy and incidence of rebound or withdrawal did not change during longterm treatment.Conclusions Abecarnil is safe and effective. Further research into its therapeutic potential seems warranted.

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ЭГАВА, Таку. "КУДО Масахиро: Исследование о Б. Пастернаке (на японском языке), Книгоиздательство ун-та Хоккайдо, Саппоро, 1988, 464 стр." Japanese Slavic and East European Studies 10 (1989): 135–37. http://dx.doi.org/10.5823/jsees.10.0_135.

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Hill, Jonathan. "Flood, Gavin. Religion and the Philosophy of Life. Oxford: Oxford University Press, 2019. 464 pp. $53.00 (cloth)." Journal of Religion 102, n.º 4 (1 de outubro de 2022): 576–78. http://dx.doi.org/10.1086/721360.

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Putra, Candra Novaliandi Pranata, e Alven Safik Ritonga. "Sistem Informasi PPDB Dengan Menerapkan Metode Simple Additive Weight (SAW) Dalam Sistem Pendukung Keputusan Pemilihan Sekolah". Journal of System Engineering and Technological Innovation (JISTI) 3, n.º 01 (28 de abril de 2024): 177–81. http://dx.doi.org/10.38156/jisti.v3i01.61.

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This research proposes and implements a web-based New Student Admission Information System (PPDB) using the Simple Additive Weight (SAW) method as a decision support system for school selection. The case study was conducted at the Lidah Kulon I/464 Surabaya Elementary School. The background of this research is driven by the significant impact of information technology advancements in the education sector. Lidah Kulon I/464 Surabaya Elementary School, as an educational institution committed to achieving excellence, discipline, faith, science and technology (IPTEK), as well as environmental awareness, strives to reduce paper usage in the new student registration process by transitioning to a more efficient administrative information system. The results of the tests state that the system has succeeded in various aspects, including the use of the Certainty Factor Method, diagnosis menu, information menu, login menu, and others. The conclusion of this research is that the system has been implemented successfully, supporting the efficiency of the PPDB process, and providing easy access to users. System development recommendations for the future include flexibility without hard coding, more comprehensive user management, the development of a more advanced school selection system, more accurate entrance fee calculations, and considerations for seasonal factors and school promotions. Keyword: PPDB Information System, Simple Additive Weight (SAW), Method Student Registration, Efficiency Educational Administration

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Liu, Qing Ye, Hao Ying Zhai e Ai Hui Liang. "Spectral Properties of K₂PtCl₆-KI-Protein Associated Particle Systems and its Application to Resonance Scattering Spectral Analysis". Advanced Materials Research 718-720 (julho de 2013): 552–56. http://dx.doi.org/10.4028/www.scientific.net/amr.718-720.552.

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In suitable pH value of Walpole buffer solution and in the presence of surfactant Triton X-10 and alcohol, PtCl62- reacts with I- to form PtI62-. By means of the electrostatic and hydrophobic forces, proteins with positive charge, such as human serum albumin (HSA), bovine serum albumin (BSA), human immunoglobulin (IgG) and ovalbumin (OVA), associates with PtI62- to form stable [protein-(PtI6)n]m association particles which cause substantial enhancement of Rayleigh scattering and interface fluorescence. They produce three Rayleigh scattering peaks at 330 nm, 420 nm and 464 nm and a resonance scattering peak at 580 nm, among which the strongest peak is at 464 nm. The four kinds of protein association particle system all exhibit a strong fluorescence peak at 466 nm, while the HSA fluorescence peak at 360 nm was quenched with the formation of the association particle. The cause of the Rayleigh scattering peaks of the association particle system was considered in detail, and the relationship between the Rayleigh scattering and fluorescence of the association particle (the means diameter is about 470 nm) and the fluorescence quenching of HSA was interpreted. Under the optimal experimental conditions, there is a good linear relationship between the scattering intensity (I464 nm) and protein concentration in the range of 0.05~25μg/mL HSA, 0.05~25μg/mL BSA, 0.3~30μg/mL IgG and 0.1~16μg/mL OVA respectively, with a detection limit of 20 ng/mL HSA, 26 ng/mL BSA, 40 ng/mL IgG and 70 ng/mL OVA. This assay has been applied to the determination of the albumin of human serum samples with satisfactory results.

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BONDÌ, ROBERTO. "GUIDO GIGLIONI, Immaginazione e malattia: saggio su Jan Baptiste van Helmont, Milano, Franco Angeli, 2000, 187 pp., L. 32.000 (ISBN 88-464-2286-4)." Nuncius 16, n.º 2 (1 de janeiro de 2001): 839–43. http://dx.doi.org/10.1163/221058701x00824.

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Głowacka, Aleksandra. "Skuteczność chwastobójcza wybranych herbicydów stosowanych w jęczmieniu jarym". Agronomy Science 76, n.º 4 (30 de dezembro de 2021): 19–28. http://dx.doi.org/10.24326/as.2021.4.2.

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Celem prowadzonych badań była ocena skuteczności chwastobójczej wybranych herbicydów stosowanych w jęczmieniu jarym, odmiana Poldek. Doświadczenie przeprowadzono w latach 2012–2014. W doświadczeniu stosowano następujące kombinacje herbicydowe: kontrola (bez odchwaszczania), Pike 20 WG (metsulfuron metylu), Aurora 40 WG (karfentrazon etylu), Tayson 464 SL + Pike 20 WG (2,4-D + dikamba + metsulfuron metylu), Pike 20 WG + Aurora 40 WG (metsulfuron metylu + karfentrazon etylu), Galmet 20 SG + Galaper 200 EC (metsulfuron metylu + fluroksypyr), Granstar Ultra SX 50 WG (tifensulfuron metylu + tribenuron metylu). Ocenę skuteczności zwalczania najliczniej występujących gatunków chwastów przeprowadzono 30 dni po zastosowaniu preparatów metodą szacunkową. Dodatkowo dwa tygodnie przed zbiorem jęczmienia oceniono wtórne zachwaszczenie łanu metodą botaniczno-wagową, określając skład florystyczny, liczebność poszczególnych gatunków oraz powietrznie suchą masę chwastów. Gatunkami dominującymi w uprawie jęczmienia były: Galinsoga parviflora, Polygonum lapathifolium subsp. lapathifolium, Galium aparine, Matricaria maritima subsp. inodora, Chenopodium album i Stellaria media. Najbardziej skuteczne w zwalczaniu dominujących w jęczmieniu gatunków chwastów były kombinacje herbicydowe Tayson 464 SL + Pike 20 WG oraz Pike 20 WG + Aurora 40 WG, Galmet 20 SG + Galaper 200 EC. Po aplikacji tych kombinacji herbicydowych uzyskano również najwyższy plon ziarna jęczmienia.

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Newman, Lenore. "Biodiversity, food, and culture Eating to Extinction Dan Saladino Farrar, Straus and Giroux, 2022. 464 pp." Science 375, n.º 6578 (21 de janeiro de 2022): 273. http://dx.doi.org/10.1126/science.abn1066.

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MANCE, JONATHAN. "Noise: A Flaw in Human Judgment , DANIELKAHNEMAN, OLIVIERSIBONY, AND CASS. R.SUNSTEIN, London: William Collins, 2021, 464 pp., £25.00". Journal of Law and Society 49, n.º 1 (14 de fevereiro de 2022): 226–31. http://dx.doi.org/10.1111/jols.12345.

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Capson, Todd L. "Our oceans, ourselves The Blue Machine: How the Ocean Works Helen Czerski Norton, 2023. 464 pp." Science 382, n.º 6666 (6 de outubro de 2023): 44. http://dx.doi.org/10.1126/science.adj7198.

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STEINKE, HUBERT. "MARIA TERESA MONTI (ed.), Écriture et mémoire. Les carnets medico-biologiques de Vallisneri a É. Wolff. Milano: Franco Angeli, 2006. 226 pp., ISBN 88-464-7937-8." Nuncius 23, n.º 1 (1 de janeiro de 2008): 164–65. http://dx.doi.org/10.1163/221058708x00340.

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De Barros Veiga, Paulo Eduardo. "Lira, vassouras e cavalinhos: um estudo sobre a imagem verbal e a expressão poética". Transições 4, n.º 2 (23 de novembro de 2023): 102–18. http://dx.doi.org/10.56344/2675-4398.v4n2a2023.5.

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Com vistas ao reconhecimento da obra poética, elabora-se uma proposta de leitura dos versos 464 a 466 do Canto IV das Geórgicas de Virgílio, que tratam do mito de Orfeu. Em particular, o interesse por poesia, haja vista a expressividade verbal e o artesanato do poeta, motivou o estudo da imagem poética, a partir das relações entre som e sentido. Sob essa proposta, abre-se uma discussão acerca dos possíveis efeitos estéticos advindos da leitura atenta dos três versos latinos, incluindo sua escansão e contextualização de referências míticas, com ênfase na inteligência sensorial do texto poético. O objetivo do artigo, em síntese, consiste na descrição de leitura detalhada de um excerto, a partir do qual se estabelecem comentários sobre expressividade poética e imagem verbal. Nesse ensejo, comparam-se os recursos métrico-prosódicos da poesia latina com a poesia em língua portuguesa, mais acessível ao falante nativo. Assim, acrescentam-se, na proposta de leitura, a estrofe 19 do Canto I dos Lusíadas de Camões e o poema “Rondó dos cavalinhos”, de Manuel Bandeira, perpassando o antigo e o moderno.

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Madera, Jessica J., Pedro Such, Maxine Chen e Ross A. Baker. "154 Functioning in de Novo and Rollover Patients with Bipolar I Disorder Receiving Aripiprazole Once-monthly in a 52-Week, Open-label Study". CNS Spectrums 25, n.º 2 (abril de 2020): 298–99. http://dx.doi.org/10.1017/s109285292000070x.

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Abstract:Introduction:Long-term maintenance treatment is essential in management of bipolar I disorder (BP-I) to achieve mood stability, prevent recurrence of mood episodes and improve functioning. Aripiprazole once-monthly 400 mg (AOM 400) is a long-acting formulation of aripiprazole for maintenance treatment of BP-I. In a double-blind, placebo-controlled, randomized withdrawal study in adult patients with BP-I after a manic episode (NCT01567527), AOM 400 delayed time to and reduced rate of recurrence of mood episodes and was safe and well tolerated (1). In an open-label, long-term safety study (NCT01710709), AOM 400 was safe and effective as long-term maintenance treatment (2).Objective:To evaluate the effect of long-term AOM 400 maintenance treatment on manic and depressive symptoms in BP-I patients from the open-label, long term safety study.Methods:Manic and depressive symptoms were assessed post-hoc by analysis of change from study entry in the Young-Mania Rating Scale (YMRS) and Montgomery-Åsberg Depression Rating Scale (MADRS) total scores and line item scores. The mean changes from baseline at last visit in YMRS and MADRS total scores, and single items were calculated using descriptive statistics, using last observation carried forward for total scores and observed cases for single items.Results:A total of 464 patients entered the maintenance phase: 379 were de novo and 85 were rollover patients who completed the double-blind, placebo-controlled withdrawal study. Overall, 63% (291/464) completed 52 weeks of open-label treatment. Mean YMRS and MADRS total scores were minimally changed from baseline (YMRS: 2.31, endpoint change -0.30; MADRS: 3.23, endpoint change +1.24) across the study in the total population.Conclusion:Patients entering an open-label safety study with stable manic and depressive symptoms maintained stability in both types of symptoms, as shown by minimal mean changes from baseline in YMRS and MADRS scores, suggesting that treatment with AOM 400 is effective in preventing re-emergence of both manic and depressive symptoms.Funding Acknowledgements:The study was supported by Otsuka Pharmaceutical Development & Commercialization, Inc.

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Madera, Jessica J., Pedro Such, Maxine Chen e Ross A. Baker. "155 Symptom Stability in de Novo and Rollover Patients with Bipolar I Disorder Receiving Aripiprazole Once-monthly in a 52-Week, Open-label Study". CNS Spectrums 25, n.º 2 (abril de 2020): 299. http://dx.doi.org/10.1017/s1092852920000711.

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Abstract:Introduction:Long-term maintenance treatment is essential in management of bipolar I disorder (BP-I) to achieve mood stability, prevent recurrence of mood episodes and improve functioning. Aripiprazole once-monthly 400 mg (AOM 400) is a long-acting formulation of aripiprazole for maintenance treatment of BP-I. In a double-blind, placebo-controlled, randomized withdrawal study in adult patients with BP-I after a manic episode (NCT01567527), AOM 400 delayed time to and reduced rate of recurrence of mood episodes and was safe and well tolerated (1). In an open-label, long-term safety study (NCT01710709), AOM 400 was safe and effective as long-term maintenance treatment (2).Objective:To evaluate the effect of long-term AOM 400 maintenance treatment on manic and depressive symptoms in BP-I patients from the open-label, long term safety study.Methods:Manic and depressive symptoms were assessed post-hoc by analysis of change from study entry in the Young-Mania Rating Scale (YMRS) and Montgomery-Åsberg Depression Rating Scale (MADRS) total scores and line item scores. The mean changes from baseline at last visit in YMRS and MADRS total scores, and single items were calculated using descriptive statistics, using last observation carried forward for total scores and observed cases for single items.Results:A total of 464 patients entered the maintenance phase: 379 were de novo and 85 were rollover patients who completed the double-blind, placebo-controlled withdrawal study. Overall, 63% (291/464) completed 52 weeks of open-label treatment. Mean YMRS and MADRS total scores were minimally changed from baseline (YMRS: 2.31, endpoint change -0.30; MADRS: 3.23, endpoint change +1.24) across the study in the total population.Conclusion:Patients entering an open-label safety study with stable manic and depressive symptoms maintained stability in both types of symptoms, as shown by minimal mean changes from baseline in YMRS and MADRS scores, suggesting that treatment with AOM 400 is effective in preventing re-emergence of both manic and depressive symptoms.Funding Acknowledgements:The study was supported by Otsuka Pharmaceutical Development & Commercialization, Inc.

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Erofeev, Nikolay. "The I-464 Housing Delivery System: A Tool for Urban Modernisation in the Socialist World and Beyond". Fabrications 29, n.º 2 (4 de maio de 2019): 207–30. http://dx.doi.org/10.1080/10331867.2019.1611255.

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Van der Auwera, Johan. "Talmy Givón, Syntax. A functional-typological introduction. Volume I. Amsterdam/Philadelphia: John Benjamins, 1984. Pp. xx + 464." Journal of Linguistics 21, n.º 2 (setembro de 1985): 503–9. http://dx.doi.org/10.1017/s0022226700010434.

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Nachtergaele, Delphine. "Three New Letters in the Thermouthas Dossier". Mnemosyne 68, n.º 1 (20 de janeiro de 2015): 53–67. http://dx.doi.org/10.1163/1568525x-12301440.

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In the present case study, I will discuss the so-called ‘dossier of Thermouthas’. It currently consists of six private letters, but I will argue in favor of the addition of three more letters to this collection: viz. P.Mich. viii 464 (tm 17238), P.Col. viii 215 (tm 17627) and P.Corn. 49 (tm 25711). My hypothesis is based on both internal arguments (linguistic and content related elements) and external ones (e.g. museum archaeology, onomastics and prosopography). This paper illustrates how idiolectic features and the close linguistic investigation of the letters’ phraseology can help the scholar reunite papyri in their original context. It refines the date of P.Corn. 49 and shows that some of the documents in this collection were preserved as an (archaeological) archive.

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Santhira Shagar, Pravina, Caroline L. Donovan, Jennifer Boddy, Caley Tapp e Neil Harris. "Does culture moderate the relationship between body dissatisfaction and quality of life? A comparative study of Australian and Malaysian emerging adults". Health Psychology Open 8, n.º 1 (janeiro de 2021): 205510292110183. http://dx.doi.org/10.1177/20551029211018378.

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Investigating moderating effects of culture between body dissatisfaction (BD) and quality of life (QoL) is paramount, as BD affects psychosocial functioning. Participants include 866 females (18–25) years old from Australia ( n = 464) M (20.88) SD (3.38) and Malaysia ( n = 402) M (20.63) SD (2.05). Higher levels of BD predicted lower levels of QoL across all four domains. BD had the strongest effect on psychological QoL for both cultures. Culture moderated the relationship between BD and: (i) physical QoL and (ii) environmental QoL. The adverse impact of BD on all domains of QoL, highlights the importance of BD as a public health problem.

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Levy, Thomas E. "Interpreting Jerusalem Under Jerusalem: The Buried History of the World’s Most Contested City Andrew Lawler Doubleday, 2021. 464 pp." Science 374, n.º 6573 (10 de dezembro de 2021): 1330. http://dx.doi.org/10.1126/science.abn0362.

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Armstrong, Wesley R., Pan Thin, Kathleen Nguyen, Rejah M. Alano, Kiara M. Booker, Jeannine Gartmann, Vincent Lok et al. "Comparison of recurrence patterns after surgery and radiation therapy with 68Ga-PSMA-11 PET/CT in nonmetastatic castrate-sensitive prostate cancer patients: A single-center post-hoc retrospective analysis in 787 patients." Journal of Clinical Oncology 38, n.º 15_suppl (20 de maio de 2020): 3577. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.3577.

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3577 Background: 20 to 50% of prostate cancer (PCa) patients undergoing radical prostatectomy (RP) or definitive radiation therapy (dRT) will experience disease recurrence. However, anatomical recurrence patterns may differ depending on the therapeutic approaches. The aim of this post-hoc retrospective analysis was to investigate if the relapse pattern as assessed by 68Ga-PSMA-11 PET/CT was different depending on the type of local pelvic therapy (RP, dRT, salvage RT (SRT), pelvic lymph node dissection (PLND), pelvic lymph node RT (PLNRT)) in patients with non-metastatic castrate sensitive (nmCS) recurrent disease after primary definitive therapy. Methods: Patients who underwent a 68Ga-PSMA-11 PET/CT for nmCS PCa recurrent disease after primary definitive therapy were screened from a database of 4 prospective studies (NCT02940262, NCT03515577, NCT04050215, NCT03582774). Patients who underwent primary staging (n = 95), without definitive therapy (n = 68), with known metastatic disease (M1) (n = 68) or with castrate resistant (CR) disease (n = 291) were excluded. We examined the relationship between recurrence patterns as assessed by 68Ga-PSMA-11 PET/CT (PROMISE criteria) and prior local treatments: i) RP, ii) dRT, iii) RP + SRT. Results: 787 patients were included in the analysis. Positive scan rates were 60%, 94% and 75% in RP, dRT and RP + SRT populations, respectively. Median pre-scan PSA levels were 0.50 (0.02-72.5) ng/ml, 4.4 (0.1-202) ng/ml, and 1.07 (0.04-33) ng/ml for patients who underwent RP (n = 464), dRT (n = 109) and post-RP SRT (n = 214). Median time to first recurrence was 27.7 after RP and 54.6 months after dRT (p = < 0.0001). Patients who underwent RP had lower local recurrence (LR) pattern (T+) rates by PSMA PET than those with dRT (99/464; 21% vs 69/109; 63%; p = < 0.0001). Nodal metastasis (N1) positivity rate was similar between RP and dRT (179/464; 39% vs 43/109; 39%; p = 0.87). Extrapelvic metastasis (M1) positivity rate was lower for RP than dRT (93/464; 20% vs 51/109; 47%; p = < 0.0001). Median time from post-RP SRT to second recurrence was 22.3 months. In patients who had a second recurrence after RP and SRT the positivity rate of LR (T+), N1 disease and M1 disease by PSMA PET/CT was 12% (24/214), 46% (99/214) and 44% (95/214). Conclusions: In this cohort of patients with nmCS PCa recurrent disease after primary definitive therapy, the patterns of failure differ based on prior local treatments.

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Lacaita, Carlo G., Antonio Maria Orecchia, Raffaella Bianchi Riva, Simone Campanozzi e Elisa Signori. "Note e recensioni". STORIA IN LOMBARDIA 43, n.º 1 (agosto de 2023): 71–93. http://dx.doi.org/10.3280/sil2023-001004.

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Anche Cattaneo tra i fondatori del pensiero di destra?Jacopo Perazzoli, Angelo Filippetti, l'ultimo sindaco di Milano prima del fascismo, refazione di Ezio Mauro, Postfazione di Andrea Jacchia, con una nota di Andrea Torre, Milano, Biblion Edizioni, 2022, 284 pp.Rosaria Marchesi e Fabio Cani, Lo specchio rotto. Giornalismo, narrazioni e documenti durante la Repubblica Sociale Italiana e la Resistenza nel Comasco 1943-1945, Como, NodoLibri, 2022, 500 pp..Marco Cuzzi, Seicento giorni di terrore a Milano. Vita quotidiana ai tempi di Salò, Vicenza, Neri Pozza Editore, 2022, 464 pp.Sergio Onger, a cura di, L'Università degli Studi di Brescia 1982-2022, Brescia, Brixia University Press, 2022, 475 pp.

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Levi, Francis, Arti Parganiha, Abdoulaye Karaboué, Pasquale F. Innominato, Sylvie Giacchetti, Carlo Garufi, Garance Dispersyn et al. "Circadian robustness as an independent predictor of prolonged progression-free survival (PFS) and overall survival (OS) in 436 patients with metastatic colorectal cancer (mCRC)." Journal of Clinical Oncology 30, n.º 4_suppl (1 de fevereiro de 2012): 464. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.464.

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464 Background: The rest-activity rhythm is a biomarker of the circadian timing system (CTS), whose disruption accelerates cancer progression in experimental models. Prior studies in cancer pts identified a reliable measure of CTS function in cancer pts based on non invasive wrist actigraphy monitoring. Methods: The prognostic value of I<O, the ratio between activity counts in-bed vs out-of-bed, was explored for PFS and OS in mCRC. The rest-activity rhythm was recorded for >48 h in 436 mCRC pts from 3 international cohorts. Data were stratified per cohort, and analyzed with Kruskall-Wallis ANOVA, log rank tests, and multivariate Cox analyses. Results: Median age was 59.2 y. Pts were mainly men (62.6%); had good performance status (PS = 0, 58.2%; 1, 33%); > 2 metastatic sites (51.6%); metastases in liver (79%) or lung (38.8%); were chemotherapy-naïve (54.6%). After baseline actigraphy recording, pts received a median of 8 courses of oxaliplatin- or irinotecan-based chemotherapy, including chronomodulated schedules (chrono; 81.4%). Despite a strong correlation with PS (p< 0.0001), I<O independently influenced both PFS and OS. Thus, both median PFS and OS nearly doubled in the pts with I<O above 97.5% (upper two quartiles) as compared to those with I<O below 93.2% (lowest quartile). Median PFS ranged from 4.8 to 10.6 months (log rank, p<0.001) and median OS from 10.1 to 20.6 months (p<0.001). In multivariate analyses, I<O ranked as the second best independent predictor of PFS, after metastases surgery, with a hazard ratio (HR) of 0.967 [95% C.L., 0.95-0.98] (p<0.001). I<O ranked as first independent predictor of OS, with a HR of 0.95 [0.94-0.97] (p<0.001). Forrest plots revealed consistent HR of I<O for PFS and OS in each cohort. Conclusions: The circadian biomarker indicator I<O is a robust, consistent and independent quantitative predictor of both PFS and OS in mCRC pts. Rest-activity rhythm monitoring deserves further testing for helping accurate determination of mCRC prognosis. The biological significance of I<O implies that specific treatments of circadian disruption could enhance survival in cancer pts.

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Cañizares-Esguerra, Jorge. "Rethinking the “Western” revolution in science Horizons: The Global Origins of Modern Science James Poskett Mariner Books, 2022. 464 pp." Science 376, n.º 6592 (29 de abril de 2022): 467. http://dx.doi.org/10.1126/science.abo5229.

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Carver, Mandy. "Theory of African Music Volumes I and II. Gerhard Kubik. 2010. Chicago: University of Chicago Press. Vol I, 464 pp., Vol II, 359 pp." African Music: Journal of the International Library of African Music 9, n.º 1 (2011): 250–51. http://dx.doi.org/10.21504/amj.v9i1.1766.

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Leezenberg, Michiel. "Timothy Brennan, Places of Mind: A Life of Edward Said. New York: Farrar, Straus & Giroux, 2021. Pp. 464. US$35.00 (cloth)." History of Humanities 7, n.º 2 (1 de setembro de 2022): 336–39. http://dx.doi.org/10.1086/721319.

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Najati, Ida, Endar Pituringsih e Animah Animah. "IMPLEMENTASI AKUNTANSI BERBASIS AKRUAL: PENGUJIAN DETERMINAN DAN IMPLEMENTASINYA TERHADAP AKUNTANSI BERBASIS AKRUAL". JURNAL AKUNTANSI UNIVERSITAS JEMBER 14, n.º 1 (30 de agosto de 2016): 1. http://dx.doi.org/10.19184/jauj.v14i1.2501.

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Abstract The study objectives are to empirically examine the effects of usage of SAIBA, accounting training and organization culture on accrual accounting implementation and its implication on quality of Ministry/Board financial accounting report (LKKL). The research population are 464 SAIBA operators of KPPN Makassar I and II stakeholders. Samples which determined by slovin technique and cluster sampling are 82 respondents. Data analysis tool used is PLS with second order confirmatory factor analysis. The finding shows that accrual accounting implementation is affected by accounting training and organization culture, but it is not affected by the usage of SAIBA. The other finding indicates that accrual accounting implementation has implication on quality of LKKL.

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Ogrodnik-Kalita, Agnieszka. "Glosa do uchwały Sądu Najwyższego z 13 maja 2015 r., III CZP 19/15, LEX nr 1679823". Studia Prawnicze KUL, n.º 4 (4 de dezembro de 2016): 159–72. http://dx.doi.org/10.31743/sp.4886.

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Przedmiotem glosy jest uchwała Sądu Najwyższego z 13 maja 2015 r. (III CZP 19/15), w której Sąd Najwyższy stwierdził, że „przedstawiciel ustawowy małoletniego dziecka może udzielić pełnomocnictwa do złożenia oświadczenia o wyrażeniu zgody przewidzianej w art. 34 ust. 3 ustawy z dnia 5 grudnia 1996 r. o zawodach lekarza i lekarza dentysty (jedn. tekst: Dz. U. z 2015 r. poz. 464)”. Sąd Najwyższy za bezwzględnie niedopuszczalne uznał udzielenie przez rodziców pełnomocnictwa ogólnego do wykonywania wszystkich czynności z zakresu władzy rodzicielskiej. Autorka, aprobując co do zasady zajęte przez Sąd Najwyższy stanowisko, analizuje związane z nim szczegółowe zagadnienia, pominięte przez Sąd Najwyższy, skupiając się na wymogach, jakie powinna spełniać osoba pełniąca funkcję pełnomocnika, a także na kwalifikacji udzielenia analizowanego pełnomocnictwa jako istotnej sprawy dziecka. Zdaniem autorki udzielenie pełnomocnictwa do wyrażenia zgody powinno być stosowane w sytuacjach zupełnie wyjątkowych, przy uwzględnieniu zastrzeżeń, wynikających z prawa cywilnego i medycznego.

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Haryani, Welas, Siti Maulidah e Munjiyati Munjiyati. "HUBUNGAN MANAJEMEN DISASTER DENGAN KESIAPSIAGAAN MAHASISWA PRODI DIII KEPERAWATAN TEGAL POLTEKKES KEMENKES SEMARANG". Juru Rawat. Jurnal Update Keperawatan 3, n.º 2 (28 de dezembro de 2023): 37–42. http://dx.doi.org/10.31983/juk.v3i2.10927.

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Latar belakang Manajemen disaster adalah kegiatan-kegiatan yang dilakukan untuk mengendalikan bencana dan kesiapsiagaan sangat penting dalam menghadapi bencana. Setiap orang harus memiliki rasa siaga dalam menghadapi bencana terlebih tim kesehatan maupun mahasiswa/i kesehatan. Tujuan : Mengetahui hubungan manajemen disaster dengan kesiapsiagaan mahasiswa/i Prodi DIII Keperawatan Tegal dalam tanggap bencana. Metode : Jenis penelitian ini adalah deskriptif korelasi dengan pendekatan cross sectional. Pengambilan sampel menggunakan teknik total sampling dengan responden sebanyak 464 orang. Hasil : Penelitian menunjukkan bahwa pemahaman manajemen disaster mahasiswa/i, Prodi DIII Keperawatan Tegal tergolong baik (94,8%), tetapi kesiapsiagaan yang dimiliki mayoritas sedang (57,3%). Hasil uji statistik Spearman Rank (Rho) diperoleh p (value) = 0,312 (p0,05), sehingga tidak ada hubungan antara manajemen disaster dengan kesiapsiagaan mahasiswa/i dalam tanggap bencana Prodi DIII Keperawatan Tegal Poltekkes Kemenkes Semarang. Kesimpulan dan saran : Intitusi Kesehatan sebaiknya memberikan kesempatan kepada mahasiswa untuk terjun langsung di tengah-tengah masyarakat dalam tim gawat darurat bencana serta peneliti berharap agar komitmen pengembangan ilmu keperawatan dibidang manajemen bencana dapat ditingkatkan melalui beberapa alternatif kegiatan seperti edukasi, simulasi, membentuk organisasi khusus penanggulangan bencana dan bekerjasama antar institusi atau organisasi kebencanaan tingkat daerah atau nasional.

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Bloom, Arthur L. "Water-Formed Structures: Geomorphology and Hydrology of Karst Terrains . William B. White. Oxford University Press, New York, 1988. xiv, 464 pp., illus. $45." Science 243, n.º 4898 (24 de março de 1989): 1618–19. http://dx.doi.org/10.1126/science.243.4898.1618.b.

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Bloom, Arthur L. "Water-Formed Structures: Geomorphology and Hydrology of Karst Terrains . William B. White. Oxford University Press, New York, 1988. xiv, 464 pp., illus. $45." Science 243, n.º 4898 (24 de março de 1989): 1618–19. http://dx.doi.org/10.1126/science.243.4898.1618-b.

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Agazzi, Elena. "Federica La Manna, Winckelmann. L’uomo che ha cambiato il modo di vedere l’arte antica. La nave di Teseo, Milano 2022. 464 S., € 22,–." Arbitrium 41, n.º 2 (1 de agosto de 2023): 178–83. http://dx.doi.org/10.1515/arb-2023-0001.

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Maier, Christoph T. "Jörg Oberste, Der Kreuzzug gegen die Albigenser. Ketzerei und Machtpolitik im Mittelalter. Darmstadt: Primus Verlag, 2003. Pp. 222. ISBN 3 89678 464 1." Crusades 5, n.º 1 (31 de dezembro de 2006): 238–39. http://dx.doi.org/10.1080/28327861.2006.12220325.

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Grafinger, Christine Maria. "Kreative Impulse und Innovationsleistungen religiöser Gemeinschaften im mittelalterlichen Europa, hrsg. Julia Becker und Julia Burkhardt. Klöster als Innovationslabore. Studien und Texte 9. Regensburg: Verlag Schnell & Steiner 2021, S. 464, 37 Abb." Mediaevistik 34, n.º 1 (1 de janeiro de 2021): 351–54. http://dx.doi.org/10.3726/med.2021.01.56.

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Zahlreiche Editionen und Auswertungen klösterlicher Texte mit innovativem Charakter durch Forscher aus Dresden und Heidelberg waren Anlass, sich auf einer Tagung in Heidelberg im Februar 2020 fächerübergreifend mit der Thematik “Invention, Innovation und Diffusion“ im Mittelalter auseinanderzusetzen. Einleitend stellen die beiden Herausgeberinnen die Frage nach Innovation und ihrer Wirkung in der mittelalterlichen Gesellschaft und schlagen vor, von “kreativen Impulsen“ zu sprechen. Die Beiträge sind vier Themenbereichen zugeordnete, denen jeweils ein repräsentativer Text eines mittelalterlichen Autors oder eine weitreichende Innovation vorangestellt ist: So steht Norbert von Xanten (1180/85‐1134) mit seiner apostolischen Lebensweise der Christusnachfolge für den ersten Themenkreis “Inspiration und Charisma“. Im zweiten Abschnitt “Technische Innovationen und regionale Visibilität“ wird auf die Errungenschaften der Zisterzienser in Wassertechnik, Forstwirtschaft und Bergbau verwiesen. Das Konzept einer idealen Gemeinschaft der Menschen von Thomas von Cantimpré (1200‐1270) in seinem Bienenbuch veranschaulicht “Netzwerke und Gemeinschaftsbildung“. Gerhoch von Reichersberg (1092/93‐1169) repräsentiert mit der Forderung nach einer Reform des Klerus und nach einer Verwirklichung einer vita apostolica – wobei er auch zeitgenössische Auffassungen rezipierte – “Wissen als Macht: Religiose als Impulsgeber“.

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Selvia P, Fanny Mega, e Chalim Chalil Yusuf. "ANALISIS BIAYA PEMESANAN DAN BIAYA PEMELIHARAAN DALAM MANAJEMEN PERSEDIAAN BAHAN BAKU (Studi pada PT. Gunawan Dianjaya Steel Tbk)". Aplikasi Administrasi: Media Analisa Masalah Administrasi 16, n.º 01 (7 de dezembro de 2017): 23. http://dx.doi.org/10.30649/aamama.v16i01.6.

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Inventory is the company's assets that have an important role in business operations, inventory shortages could result in the cessation of the production process and if you are inventory too large (over stock) can result in very high costs to store and preserve the material during storage thus company needs to make proactive inventory management, meaning that the company should he able to minimize the total cost to be incurred related to the supply of raw materialsIn PT Gunawan Dianjaya Steel Corporation, can be seen on the inventory management policies in terms of fees and maintenance costs of raw materials, PT Gunawan Dianjaya Steel Tbk alone can not determine when to hold back ordering or commonly called the reorder point, so the company made a purchase raw materials as much as I Ox within a period of I year during 2010 with a quantity of 286 464 748 kgKeywords: Inventory, Economic Order Quantity (EOQ) and Reorder Point

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Bagatell, R., X. Liu, Whitesell e J. J. Hutter. "#464 Inhibition of insulin-like growth factor I receptor expression in neuroblastoma tumors elicits a potent cytotoxic T-cell response". Journal of Pediatric Hematology/Oncology 21, n.º 4 (julho de 1999): 331. http://dx.doi.org/10.1097/00043426-199907000-00110.

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Leake, Bernard Elgey. "New light on the Oughterard Granite: Connemara's S-Type granite, Ireland". Irish Journal of Earth Sciences 41, n.º 1 (2024): 33–43. http://dx.doi.org/10.1353/ijes.2023.a918662.

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Abstract: Most of the Connemara granites, including the Galway Granite batholith, have a clearly defined circular or ellipsoidal outcrop shape and are I-Type granites often with K-feldspar phenocrysts, whereas the Oughterard Granite (OG) forms numerous small intrusions scattered east-west over 40km with two larger linked bodies near Oughterard and is S-Type and aphyric. The only comprehensive mapping, mineralogical and chemical study of the OG was published over 50 years ago before the important 1974 recognition of the distinction of I- and S-Type granites was first made. New mapping of the southern Oughterard area with small OG intrusions is presented and many scattered published chemical and Rb, Sr, S and Pb isotopic studies integrated to confirm overall their individual conclusions that the peraluminous OG is of S-Type, being formed from melted Dalradian rocks as are the fluid-carried associated uneconomic mineral deposits. The OG is confined to the high sillimanite zone, mostly south of, and mainly later than, the 465-464Ma D4 Connemara Antiform, where a wide (>15km N-S) >70km E-W band of 469Ma gabbros and 467Ma quartz diorite gneisses intruded into already hot Dalradian rocks undergoing regional metamorphism. This generated the OG magmas by partial melting of pelites and semi-pelites. The upward intrusion of the OG magma was significantly delayed, as has been shown by precise dating in other granites elsewhere, to ∼464-461Ma during the late stages and mostly after D4 but before the country rocks had completely cooled. The OG intrusions as a whole probably form the second largest area of S-Type granite in Ireland, after the Leinster Granite.

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Brunner, Benedikt. "Joachim Scholtyseck, Die National-Bank. Von der Bank der christlichen Gewerkschaften zur Mittelstandsbank, 1921–2021, C.H. Beck, München 2021, 464 S., € 39,95." Zeitschrift für Unternehmensgeschichte 68, n.º 2 (11 de setembro de 2023): 315–16. http://dx.doi.org/10.1515/zug-2023-0026.

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Uematsu, Daisuke, Joel H. Greenberg, Nobuo Araki e Martin Reivich. "Mechanism Underlying Protective Effect of MK-801 against NMDA-Induced Neuronal Injury in vivo". Journal of Cerebral Blood Flow & Metabolism 11, n.º 5 (setembro de 1991): 779–85. http://dx.doi.org/10.1038/jcbfm.1991.135.

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The effects of the N-methyl-D-aspartate (NMDA) receptor antagonist MK-801 and the dihydropyridine calcium antagonist nimodipine on NMDA-induced phenomena were investigated using an in vivo fluorometric technique with indo-1. Indo-1, a fluorescent cytosolic free calcium ([Ca2+]i) indicator, was loaded into the cat cortex approximately 500 μm in depth by super-fusion with the membrane-permeant indo-1 acetoxymethyl ester (indo-1-AM). Changes in [Ca2+]i signals (400 and 506 nm) and reduced nicotinamide adenine dinucleotide (NADH) fluorescence (464 nm) were simultaneously measured directly from the cortex during ultraviolet excitation (340 nm). Superfusion of 100 μM NMDA over the exposed cortex induced an elevation of the [Ca2+]i signal ratio (400/506 nm), biphasic changes in NAD/NADH redox state (initial oxidation followed by progressive reduction), and characteristic changes in the EEG (abrupt depression in amplitude followed by an excitatory pattern of 18–22 Hz poly spikes or sharp waves). These changes were completely blocked by treatment with MK-801 and reduced by nimodipine. The mechanism underlying the protective effects of systemically administered MK-801 on the NMDA-induced neuronal injury was verified in vivo.

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Li, Sheng, Jing Huang, Ying Wang e Peng Liu. "Synthesis, Crystal Structure and Fluorescence Study of 8-Dimethylaminomethyl-7-hydroxy-chromen-2-one①". Advanced Materials Research 881-883 (janeiro de 2014): 181–86. http://dx.doi.org/10.4028/www.scientific.net/amr.881-883.181.

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A new coumarin derivative 8-Dimethylaminomethyl-7-hydroxy-chromen-2-one (C12H13NO3,M= 219.23) were prepared and characterized by single-crystal X-ray diffraction. The compound crystallized in methyl alcohol system. The crystal belongs to the Monoclinic system, space groupP21/C, witha= 10.228(2) Å,b= 8.9260(18) Å,c= 12.064(2) Å,α= 90°,β= 91.85(3)°,γ= 90°,M= 219. 23,V= 1100.8(4) Å3,Z= 4,Dc = 1.323 g/cm3,μ=0.096 mm-1,F(000) = 464,R= 0.0594 andwR= 0.1611. A total of 2136 unique reflections were collected, of which 2020 withI>2(I) were observed. The quantum chemistry calculation study on the title compound has been performed by quantum chemical method in SVWN5/6-31G**level. Additionally, IR,1HNMR spectra, thermal analysis and the fluorescent properties are discussed .

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