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Artigos de revistas sobre o assunto "He57"

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Batra, Priyanka, Monika Barkodia, Umang Ahlawat, Rekha Sansanwal, Rajesh Kumar Vaid e Leela Wati. "Identification and characterization of promising endophytic bacteria for growth promotion in chickpea (Cicer arietinum)". Indian Journal of Agricultural Sciences 90, n.º 4 (10 de julho de 2020): 708–12. http://dx.doi.org/10.56093/ijas.v90i4.102207.

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The present study was carried out for the isolation and characterization of endophytic bacteria from chickpea nodules. A total of 107 endophytes were isolated from five districts of Haryana using three media, viz. YEMA for rhizobia, Pikovskaya and TSA for non-rhizobial isolates. The endophytes were then screened for various growth promoting traits like IAA production, Phosphate solubilization, Siderophore production, ACC utilization, Potassium solubilization and tolerance to NaCl concentrations. Total six endophytes, one rhizobium (HM2) and five non-rhizobial endophytes (RE6, BE13, ME3, HE5, HE7) were selected based on of plant growth promoting traits. Furthermore, the most promising non-rhizobial endophytes RE6 and BE13, compatible with Rhizobial isolate HM2 were Pseudomonas protegens and Bacillus boroniphilus using 16s rDNA sequencing. Both the isolates are non-pathogenic to humans and thus, are potential plant probiotics that can be used as biofertilizers.
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Hong, Woojae, Jeon Hwang-Bo, Hyelin Jeon, Minsung Ko, Joongyeon Choi, Yong-Joon Jeong, Jae-Hyun Park et al. "A Comparative Study of the Hepatoprotective Effect of Centella asiatica Extract (CA-HE50) on Lipopolysaccharide/d-galactosamine-Induced Acute Liver Injury in C57BL/6 Mice". Nutrients 13, n.º 11 (15 de novembro de 2021): 4090. http://dx.doi.org/10.3390/nu13114090.

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Acute liver failure (ALF) refers to the sudden loss of liver function and is accompanied by several complications. In a previous study, we revealed the protective effect of Centella asiatica 50% ethanol extract (CA-HE50) on acetaminophen-induced liver injury. In the present study, we investigate the hepatoprotective effect of CA-HE50 in a lipopolysaccharide/galactosamine (LPS-D-Gal)-induced ALF animal model and compare it to existing therapeutic silymarin, Lentinus edodes mycelia (LEM) extracts, ursodeoxycholic acid (UDCA) and dimethyl diphenyl bicarboxylate (DDB). Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were decreased in the CA-HE50, silymarin, LEM, UDCA and DDB groups compared to the vehicle control group. In particular, AST and ALT levels of the 200 mg/kg CA-HE50 group were significantly decreased compared to positive control groups. Lactate dehydrogenase (LDH) levels were significantly decreased in the CA-HE50, silymarin, LEM, UDCA and DDB groups compared to the vehicle control group and LDH levels of the 200 mg/kg CA-HE50 group were similar to those of the positive control groups. Superoxide dismutase (SOD) activity was significantly increased in the 100 mg/kg CA-HE50, LEM and UDCA groups compared to the vehicle control group and, in particular, the 100 mg/kg CA-HE50 group increased significantly compared to positive control groups. In addition, the histopathological lesion score was significantly decreased in the CA-HE50 and positive control groups compared with the vehicle control group and the histopathological lesion score of the 200 mg/kg CA-HE50 group was similar to that of the positive control groups. These results show that CA-HE50 has antioxidant and hepatoprotective effects at a level similar to that of silymarin, LEM, UDCA and DDB, which are known to have hepatoprotective effects; further, CA-HE50 has potential as a prophylactic and therapeutic agent in ALF.
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Park, Dae-Won, Yeong-Geun Lee, Yong-Joon Jeong, Hyelin Jeon e Se-Chan Kang. "Preventive Effects against Retinal Degeneration by Centella asiatica Extract (CA-HE50) and Asiaticoside through Apoptosis Suppression by the Nrf2/HO-1 Signaling Pathway". Antioxidants 10, n.º 4 (16 de abril de 2021): 613. http://dx.doi.org/10.3390/antiox10040613.

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Age-related macular degeneration (AMD) is caused by the chronic and gradual oxidative degeneration of the retina. Unfortunately, the general purpose of current treatments is to slow AMD progression, as the retina cannot be restored to its pre-AMD condition. We aimed to identify natural products that can be potential treatments that prevent AMD and can delay the development of late-AMD and selected Centella asiatica extract (CA-HE50), which shows excellent efficacy in cytoprotection. In animal experiments using N-methyl-N-nitrosourea (MNU), CA-HE50 dramatically increased the thickness of photoreceptors and the outer nuclear layer (ONL) and the number of nuclei in the ONL (p < 0.05). Using retinal epithelial ARPE-19 cells showed that CA-HE50 inhibited apoptosis through inhibition of the intrinsic apoptosis signaling pathway and cell cycle regulation (p < 0.05). The anti-apoptotic efficacy was confirmed to be due to activation of the Nrf2/HO-1 antioxidation pathway (p < 0.05). These results were also observed with asiaticoside, a functional substance of CA-HE50. In addition, the accumulation of oxidized-N-retinylidene-N-retinylethanolamine (A2E), which induces AMD, was inhibited by CA-HE50, resulting in increased ARPE-19 cell viability (p < 0.05). This study demonstrates that CA-HE50 is worth further research and human application tests, to develop it as a raw material for treatment or dietary supplement for the prevention of AMD.
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Oates, Andrew C., e Robert K. Ho. "Hairy/E(spl)-related(Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish". Development 129, n.º 12 (15 de junho de 2002): 2929–46. http://dx.doi.org/10.1242/dev.129.12.2929.

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We have examined the expression of a Hairy/E(spl)-related (Her) gene, her7, in the zebrafish and show that its expression in the PSM cycles similarly to her1 and deltaC. A decrease in her7 function generated by antisense oligonucleotides disrupts somite formation in the posterior trunk and tail, and disrupts the dynamic expression domains of her1 and deltaC, suggesting that her7 plays a role in coordinating the oscillations of neighboring cells in the presomitic mesoderm. This phenotype is reminiscent of zebrafish segmentation mutants with lesions in genes of the Delta/Notch signaling pathway, which also show a disruption of cyclic her7 expression. The interaction of HER genes with the Delta/Notch signaling system was investigated by introducing a loss of her7 function into mutant backgrounds. This leads to segmental defects more anterior than in either condition alone. Combining a decrease of her7 function with reduction of her1 function results in an enhanced phenotype that affects all the anterior segments, indicating that Her functions in the anterior segments are also partially redundant. In these animals, gene expression does not cycle at any time, suggesting that a complete loss of oscillator function had been achieved. Consistent with this, combining a reduction of her7 and her1 function with a Delta/Notch mutant genotype does not worsen the phenotype further. Thus, our results identify members of the Her family of transcription factors that together behave as a central component of the oscillator, and not as an output. This indicates, therefore, that the function of the segmentation oscillator is restricted to the positioning of segmental boundaries. Furthermore, our data suggest that redundancy between Her genes and genes of the Delta/Notch pathway is in part responsible for the robust formation of anterior somites in vertebrates.
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Henry, Clarissa A., Michael K. Urban, Kariena K. Dill, John P. Merlie, Michelle F. Page, Charles B. Kimmel e Sharon L. Amacher. "Two linkedhairy/Enhancer of split-related zebrafish genes,her1andher7, function together to refine alternating somite boundaries". Development 129, n.º 15 (1 de agosto de 2002): 3693–704. http://dx.doi.org/10.1242/dev.129.15.3693.

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The formation of somites, reiterated structures that will give rise to vertebrae and muscles, is thought to be dependent upon a molecular oscillator that may involve the Notch pathway. hairy/Enhancer of split related [E(spl)]-related (her or hes) genes, potential targets of Notch signaling, have been implicated as an output of the molecular oscillator. We have isolated a zebrafish deficiency, b567, that deletes two linked her genes, her1 and her7. Homozygous b567 mutants have defective somites along the entire embryonic axis. Injection of a combination of her1 and her7 (her1+7) morpholino modified antisense oligonucleotides (MOs) phenocopies the b567 mutant somitic phenotype, indicating that her1 and her7 are necessary for normal somite formation and that defective somitogenesis in b567 mutant embryos is due to deletion of her1 and her7. Analysis at the cellular level indicates that somites in her1+7-deficient embryos are enlarged in the anterior-posterior dimension. Weak somite boundaries are often found within these enlarged somites which are delineated by stronger, but imperfect, boundaries. In addition, the anterior-posterior polarity of these enlarged somites is disorganized. Analysis of her1 MO-injected embryos and her7 MO-injected embryos indicates that although these genes have partially redundant functions in most of the trunk region, her1 is necessary for proper formation of the anteriormost somites and her7 is necessary for proper formation of somites posterior to somite 11. By following somite development over time, we demonstrate that her genes are necessary for the formation of alternating strong somite boundaries. Thus, even though two potential downstream components of Notch signaling are lacking in her1+7-deficient embryos, somite boundaries form, but do so with a one and a half to two segment periodicity.
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Murakami, Kohki, Soki Tanai, Takafumi Okuda, Jun Suda, Tsunenobu Kimoto e Takahide Umeda. "ESR Study on Hydrogen Passivation of Intrinsic Defects in p-Type and Semi-Insulating 4H-SiC". Materials Science Forum 858 (maio de 2016): 318–21. http://dx.doi.org/10.4028/www.scientific.net/msf.858.318.

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We studied the hydrogen passivation/depassivation of four types of intrinsic defects (EI5/6, HEI7/8, HEI9/10, and P6/7) in p-type and semi-insulating 4H-SiC by means of electron spin resonance (ESR) for examining the origin of career-lifetime-killing defects. We suggest that the HEI7/8 and P6/7 centers are the strongest candidate for the origin of the lifetime-killing defects.
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Li, Yan, Yu Ling Liu, Hong Bo Li, Ao Chen Wang, Wei Juan Liu e Jiao Hong. "Optimization of Chemical Mechanical Planarization Process of High Enrichment Slurry Under Low Pressure". Key Engineering Materials 645-646 (maio de 2015): 291–96. http://dx.doi.org/10.4028/www.scientific.net/kem.645-646.291.

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The polishing process was optimized according to the polishing rate and its consistency of HE slurry with different dilution multiple on the copper wafers, it can be confirmed that: the best pressure value of HE1, HE10, HE20, HE50 type slurries was 6890Pa, the best flow rate value of the preceding three slurries was 300ml/min, the best value of the HE50 slurry was 400ml/min. Through the planarization effects of the slurries with different dilution multiple, it can be obtained that: the initial dishing and erosion heights of the samples were both 1270nm and -500nm, and the two values respectively changed to 539.3nm, -75.7nm and 796.3nm, -191.3nm after being treated by HE1 and HE10 slurries, the step height of the wafer changed from 117nm to 72nm after being treated by HE20 slurry, the step height of the wafer changed from 88nm to 71nm after being treated by HE50 slurry. It was concluded that: the HE slurry shows strong ability for step removal when the slurry is diluted by 1 times and 10 times, the HE slurry also owns high planarization ability when the slurry is diluted by 20 times and 50 times.
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Matsuda, Mitsuhiro, Hanako Hayashi, Jordi Garcia-Ojalvo, Kumiko Yoshioka-Kobayashi, Ryoichiro Kageyama, Yoshihiro Yamanaka, Makoto Ikeya, Junya Toguchida, Cantas Alev e Miki Ebisuya. "Species-specific segmentation clock periods are due to differential biochemical reaction speeds". Science 369, n.º 6510 (17 de setembro de 2020): 1450–55. http://dx.doi.org/10.1126/science.aba7668.

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Although mechanisms of embryonic development are similar between mice and humans, the time scale is generally slower in humans. To investigate these interspecies differences in development, we recapitulate murine and human segmentation clocks that display 2- to 3-hour and 5- to 6-hour oscillation periods, respectively. Our interspecies genome-swapping analyses indicate that the period difference is not due to sequence differences in the HES7 locus, the core gene of the segmentation clock. Instead, we demonstrate that multiple biochemical reactions of HES7, including the degradation and expression delays, are slower in human cells than they are in mouse cells. With the measured biochemical parameters, our mathematical model accounts for the two- to threefold period difference between the species. We propose that cell-autonomous differences in biochemical reaction speeds underlie temporal differences in development between species.
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Lafaye, G., e A. Benyamina. "Clock genes SNP array identifies a key role of the PER1/HES7 gene in the risk of cannabis addiction and psychiatric comorbidities". European Psychiatry 41, S1 (abril de 2017): s867—s868. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1739.

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The existence of biological rhythms disruption in addicted subjects has been described including disturbances in their sleep-wake pattern, rest-activity rhythms, and feeding schedules. Circadian rhythms have also been related to psychiatric diseases, including mood and anxiety disorders and the regulation of dopaminergic transmission, especially in reward circuitry in substance abusers. The relationship between them remained enigmatic and no data on the role of clock genes variants on cannabis dependence have been documented. We aimed at exploring the role of clock gene genotypes as potential predisposing factor to cannabis addiction, using a high throughput mass spectrometry methodology that enables the large-scale analysis of all the known clinically-relevant polymorphisms of the core human clock genes. We have conducted a case-control study on 177 Caucasians categorizing between cannabis-addicted subjects (n = 83) and casual cannabis consumers (n = 94). We report here a strong association between the TT* genotype RS1442849 in PER1/HES7 gene and a significantly higher risk of vulnerability to be dependent to cannabis. Moreover, this SNP was overrepresented in the subsets of cannabis users with more severe characteristics like personal psychiatric history, unemployed status, and beginning of cannabis use early in lifetime as well as large weekly consumption. HES7 gene is a newly described gene with a circadian expression regulated by reactive oxygen species in many cell types including neural stem cells. The HES7 TT* genotype RS1442849 gene could intervene on the dopamine reward systems. This genotype thus represents the first potential biomarker for stratification of cannabis consumers for the risk to develop a true dependence.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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Adahchour, A., e P. Descouvemont. "Core excitations in He8 and He7". Physics Letters B 639, n.º 5 (agosto de 2006): 447–50. http://dx.doi.org/10.1016/j.physletb.2006.05.092.

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Teses / dissertações sobre o assunto "He57"

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Aldana, Hidalgo Julio Xavier, Parodi Augusto José Amador, Palacios Jorge Martin Arredondo, Aguilar Carla Barrionuevo, Ortiz Carol Elizabeth Beltrán, Fuentes Carlos Arturo Capellino, Alcazar Martin Roberto Cervetto et al. "Estrategias de redacción - HE59 201801". Universidad Peruana de Ciencias Aplicadas (UPC), 2018. http://hdl.handle.net/10757/624389.

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Descripción: Estrategias de Redacción es un curso de Humanidades, que brinda al participante un conjunto de herramientas lingüísticas para la redacción en el entorno laboral, tales como el uso apropiado de la normativa del español y la aplicación de estrategias de redacción como la enumerativa y la causal. Estas últimas se emplean en la elaboración de un tipo de documento: el informe de recomendación. Propósito: El curso desarrolla la competencia de comunicación escrita en el primer nivel de logro. La asignatura se orienta a la redacción de textos administrativos que ayuden a optimizar el desempeño profesional del participante, ya sea en el entorno universitario o en el ámbito laboral.
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(UPC), Universidad Peruana de Ciencias Aplicadas, e Celis Ingunza Sandy Cecilia. "Creatividad Y Liderazgo-HE50-201601". Universidad Peruana de Ciencias Aplicadas (UPC), 2016. http://hdl.handle.net/10757/639326.

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Creatividad y Liderazgo es un curso de formación general de carácter teórico y práctico que está dirigido a estudiantes de quinto ciclo a más de las Facultades de negocios e Ingeniería y que desarrolla una de las competencias generales de nuestro modelo educativo: Pensamiento Innovador.El curso Creatividad y Liderazgo surge como una respuesta a los vertiginosos cambios tecnológicos y sociales que ocurren en nuestros días los que a su vez producen profundas transformaciones en la cultura corporativa de empresas e instituciones. Esto enfrenta a los ejecutivos a cada vez mayores exigencias profesionales requeridas por las organizaciones que necesitan personas capaces de ejercer un liderazgo en equipos gestores de cambio e innovación. La formación por competencias que se brinda permite al estudiante ejecutivo un aprender haciendo. Las experiencias de aprendizaje se desarrollan en espacios de experimentación y simulación que facilitan al estudiante transferir lo aprendido de manera autónoma a los diferentes ámbitos de su vida y en particular al laboral. Así la formación que llevamos a cabo centra su atención en estrategias de indagación crítica y creativa de problemas reales influencia en los procesos de deliberación así como los modos de interacción. El objetivo central es preparar al ejecutivo para enfrentar de manera exitosa dos problemas: la resolución creativa de problemas y capacitarlos en el ejercicio de un liderazgo proactivo dentro de equipos de trabajo marcados cada vez más por una naturaleza interdisciplinaria.
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(UPC), Universidad Peruana de Ciencias Aplicadas, e Garcia Soria Juddy Grethel Nora. "Creatividad Y Liderazgo-HE50-201602". Universidad Peruana de Ciencias Aplicadas (UPC), 2016. http://hdl.handle.net/10757/639327.

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Creatividad y Liderazgo es un curso de formación general de carácter teórico y práctico que está dirigido a estudiantes de quinto ciclo a más de las Facultades de negocios e Ingeniería y que desarrolla una de las competencias generales de nuestro modelo educativo: Pensamiento Innovador.El curso Creatividad y Liderazgo surge como una respuesta a los vertiginosos cambios tecnológicos y sociales que ocurren en nuestros días los que a su vez producen profundas transformaciones en la cultura corporativa de empresas e instituciones. Esto enfrenta a los ejecutivos a cada vez mayores exigencias profesionales requeridas por las organizaciones que necesitan personas capaces de ejercer un liderazgo en equipos gestores de cambio e innovación. La formación por competencias que se brinda permite al estudiante ejecutivo un aprender haciendo. Las experiencias de aprendizaje se desarrollan en espacios de experimentación y simulación que facilitan al estudiante transferir lo aprendido de manera autónoma a los diferentes ámbitos de su vida y en particular al laboral. Así la formación que llevamos a cabo centra su atención en estrategias de indagación crítica y creativa de problemas reales influencia en los procesos de deliberación así como los modos de interacción. El objetivo central es preparar al ejecutivo para enfrentar de manera exitosa dos problemas: la resolución creativa de problemas y capacitarlos en el ejercicio de un liderazgo proactivo dentro de equipos de trabajo marcados cada vez más por una naturaleza interdisciplinaria.
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(UPC), Universidad Peruana de Ciencias Aplicadas, e Ilizarbe Jurado Anndy Antonio. "Creatividad Y Liderazgo-HE50-201701". Universidad Peruana de Ciencias Aplicadas (UPC), 2017. http://hdl.handle.net/10757/639328.

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Creatividad y Liderazgo es un curso de formación general de carácter teórico y práctico que está dirigido a estudiantes de quinto ciclo a más de las Facultades de Negocios e Ingeniería y busca desarrollar una de las competencias generales de nuestro modelo educativo: Pensamiento Innovador.El curso Creatividad y Liderazgo surge como una respuesta a la necesidad de profesionales que cuenten con estrategias y metodologías para afrontar los vertiginosos cambios que ocurren en nuestros días los que a su vez producen profundas transformaciones en la cultura corporativa de empresas e instituciones. Esto enfrenta a los ejecutivos a cada vez mayores exigencias por parte de las organizaciones las cuales requieren personas capaces de involucrar en su práctica y ejercer cotidianamente un liderazgo en equipos gestores de cambio e innovación.La formación por competencias que se brinda permite al estudiante ejecutivo un aprender haciendo. Las experiencias de aprendizaje se desarrollan en espacios de experimentación y simulación que facilitan al estudiante transferir lo aprendido de manera autónoma a los diferentes ámbitos de su vida y en particular al laboral. Así la formación que llevamos a cabo centra su atención en estrategias de indagación crítica y creativa de problemas reales influencia en los procesos de deliberación así como los modos de interacción. El objetivo central es preparar al ejecutivo para enfrentar de manera exitosa dos situaciones: la resolución creativa de problemas y capacitarlos en el ejercicio de un liderazgo proactivo dentro de equipos de trabajo marcados cada vez más por una naturaleza interdisciplinaria.
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Yoshioka, Kumiko. "Coupling delay controls synchronized oscillation in the segmentation clock". Kyoto University, 2020. http://hdl.handle.net/2433/253153.

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Takagi, Akari. "Dynamic Delta‐like1 expression in presomitic mesoderm cells during somite segmentation". Kyoto University, 2020. http://hdl.handle.net/2433/253186.

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播磨, 有希子. "Hes7遺伝子のイントロン削減による分節時計の加速化". 京都大学 (Kyoto University), 2013. http://hdl.handle.net/2433/175183.

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Nagel, Olaf. "HE5-CD52 und die [alpha]1-3-Fucosyltransferasen [Alpha-1-3-Fucosyltransferasen] des humanen Nebenhodens". [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968647464.

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Niwa, Yasutaka. "The Initiation and Propagation of Hes7 Oscillation Are Cooperatively Regulated by Fgf and Notch Signaling in the Somite Segmentation Clock". Kyoto University, 2009. http://hdl.handle.net/2433/124301.

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Sielaff, Bernhard. "Molekulare Analyse der Gene und Proteine der Cytochrom P450-haltigen Morpholin-Monooxygenase aus Mycobacterium sp. Stamm HE5". [S.l. : s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=975691856.

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Livros sobre o assunto "He57"

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cai, Jin sheng. Ping di ke ^wei guan jing ji xue~ (di4 he5 ban) bi ji he ke hou xi ti xiang jie. Bei jing: Zhong guo shi hua chu ban she, 2006.

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Kay, Bartholomew L., ed. Planning health promotion programs: An intervention mapping approach. San Francisco: Jossey-Bass, 2006.

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Occupational Health Law. Wiley & Sons, Incorporated, John, 2020.

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Occupational Health Law. Wiley & Sons, Limited, John, 2008.

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Occupational Health Law. Wiley & Sons, Limited, John, 2010.

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Safety and Health for Engineers. Wiley & Sons Australia, Limited, John, 2005.

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Safety and health for engineers. 2a ed. Hoboken, N.J: John Wiley, 2005.

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Safety and health for engineers. Hoboken: Wiley, 2016.

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Safety and health for engineers. New York: Van Nostrand Reinhold, 1990.

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Safety and Health for Engineers. Wiley & Sons Canada, Limited, John, 2006.

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Capítulos de livros sobre o assunto "He57"

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Hall, Christine M., Amaka C. Offiah, Francesca Forzano, Mario Lituania, Gen Nishimura e Valérie Cormier-Daire. "Spondylocostal Dysostosis, DLL3-, MESP2-, LFNG-, HES7-, TBX6- and RIPPLY2-Related". In Fetal and Perinatal Skeletal Dysplasias, 517–20. 2a ed. Boca Raton: CRC Press, 2024. http://dx.doi.org/10.1201/9781003166948-113.

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Sanaki-Matsumiya, Marina, e Ryoichiro Kageyama. "Time-Lapse Bioluminescence Imaging of Hes7 Expression In Vitro and Ex Vivo". In Bioluminescence, 321–32. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2473-9_25.

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Leier, André, Kevin Burrage e Pamela Burrage. "Stochastic Modelling and Simulation of Coupled Autoregulated Oscillators in a Multicellular Environment: The her1/her7 Genes". In Computational Science – ICCS 2007, 778–85. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-72584-8_103.

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Turnpenny, Peter D., Kenro Kusumi e Sally L. Dunwoodie. "DLL3, MESP2, LFNG, HES7, TBX6, RIPPLY2 and Spondylocostal Dysostosis". In Epstein's Inborn Errors of Development, 559–70. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199934522.003.0074.

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Peacocke, Arthur. "The Doctrine Of Creation In The Light Of The Scientific World-View". In Creation and The World OF Science, 77–85. Oxford University PressOxford, 2004. http://dx.doi.org/10.1093/oso/9780199271696.003.0013.

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Abstract Certain clarifications are required from the outset. In saying that God is, and that God is Creator, we do not affirm that he/ she (rather than it, for personal pronouns are now clearly less misleading than impersonal ones) is any ordinary ‘cause’ in the physical nexus of the universe itself-otherwise God would be neither explanation nor possible meaning. He47 cannot be the old ‘God of the gaps’-but we shall have to explore, in the light of the scientific account of the world, what images are best now employed to unfold the relation of the all-embracing reality of God to that world to which he stands as Creator.
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Barrio, Manuel, Kevin Burrage, Pamela Burrage, André Leier e Tatiana Márquez Lago. "Computational Approaches for Modeling Intrinsic Noise and Delays in Genetic Regulatory Networks". In Handbook of Research on Computational Methodologies in Gene Regulatory Networks, 169–97. IGI Global, 2010. http://dx.doi.org/10.4018/978-1-60566-685-3.ch007.

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This chapter focuses on the interactions and roles between delays and intrinsic noise effects within cellular pathways and regulatory networks. We address these aspects by focusing on genetic regulatory networks that share a common network motif, namely the negative feedback loop, leading to oscillatory gene expression and protein levels. In this context, we discuss computational simulation algorithms for addressing the interplay of delays and noise within the signaling pathways based on biological data. We address implementational issues associated with efficiency and robustness. In a molecular biology setting we present two case studies of temporal models for the Hes1 gene (Monk, 2003; Hirata et al., 2002), known to act as a molecular clock, and the Her1/Her7 regulatory system controlling the periodic somite segmentation in vertebrate embryos (Giudicelli and Lewis, 2004; Horikawa et al., 2006).
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"4 General principles". In ANSI/AAMI HE75:2009/(R)2018; Human factors engineering – Design of medical devices. AAMI, 2010. http://dx.doi.org/10.2345/9781570203640.ch04.

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"14 Cross-cultural/cross-national design". In ANSI/AAMI HE75:2009/(R)2018; Human factors engineering – Design of medical devices. AAMI, 2010. http://dx.doi.org/10.2345/9781570203640.ch14.

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"5 Managing the risk of use error". In ANSI/AAMI HE75:2009/(R)2018; Human factors engineering – Design of medical devices. AAMI, 2010. http://dx.doi.org/10.2345/9781570203640.ch05.

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"16 Accessibility considerations". In ANSI/AAMI HE75:2009/(R)2018; Human factors engineering – Design of medical devices. AAMI, 2010. http://dx.doi.org/10.2345/9781570203640.ch16.

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Trabalhos de conferências sobre o assunto "He57"

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"HE5: temperature measurement". In Proceedings of the 21st IEEE Instrumentation and Measurement Technology Conference. IEEE, 2004. http://dx.doi.org/10.1109/imtc.2004.1351517.

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