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1

Shatillo, Artem, Juho Koponen, Tuukka Miettinen, Anna-Mari Karkkainen e Antti Nurmi. "Functional Ultrasound". Genetic Engineering & Biotechnology News 39, n.º 4 (abril de 2019): 52–54. http://dx.doi.org/10.1089/gen.39.04.16.

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Montaldo, Gabriel, Alan Urban e Emilie Macé. "Functional Ultrasound Neuroimaging". Annual Review of Neuroscience 45, n.º 1 (8 de julho de 2022): 491–513. http://dx.doi.org/10.1146/annurev-neuro-111020-100706.

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Functional ultrasound (fUS) is a neuroimaging method that uses ultrasound to track changes in cerebral blood volume as an indirect readout of neuronal activity at high spatiotemporal resolution. fUS is capable of imaging head-fixed or freely behaving rodents and of producing volumetric images of the entire mouse brain. It has been applied to many species, including primates and humans. Now that fUS is reaching maturity, it is being adopted by the neuroscience community. However, the nature of the fUS signal and the different implementations of fUS are not necessarily accessible to nonspecialists. This review aims to introduce these ultrasound concepts to all neuroscientists. We explain the physical basis of the fUS signal and the principles of the method, present the state of the art of its hardware implementation, and give concrete examples of current applications in neuroscience. Finally, we suggest areas for improvement during the next few years.
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3

de Korte, Chris L., e Hendrik H. G. Hansen. "FOCUS: FUNCTIONAL IMAGING - ULTRASOUND". Artery Research 7, n.º 3-4 (2013): 110. http://dx.doi.org/10.1016/j.artres.2013.10.387.

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4

Tyler, William J., Yusuf Tufail e Sandipan Pati. "Noninvasive functional neurosurgery using ultrasound". Nature Reviews Neurology 6, n.º 1 (janeiro de 2010): 13–14. http://dx.doi.org/10.1038/nrneurol.2009.211.

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5

Gilja, Odd Helge. "Ultrasound in functional GI disorders". Ultrasound in Medicine & Biology 45 (2019): S14—S15. http://dx.doi.org/10.1016/j.ultrasmedbio.2019.07.458.

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Martinez de Paz, Jose Maria, e Emilie Macé. "Functional ultrasound imaging: A useful tool for functional connectomics?" NeuroImage 245 (dezembro de 2021): 118722. http://dx.doi.org/10.1016/j.neuroimage.2021.118722.

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7

Lin, Yan, Zhi-Yi Chen e Feng Yang. "Ultrasound-Based Multimodal Molecular Imaging and Functional Ultrasound Contrast Agents". Current Pharmaceutical Design 19, n.º 18 (1 de abril de 2013): 3342–51. http://dx.doi.org/10.2174/1381612811319180016.

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Lin, Yan, Zhi-Yi Chen e Feng Yang. "Ultrasound-Based Multimodal Molecular Imaging and Functional Ultrasound Contrast Agents". Current Pharmaceutical Design 999, n.º 999 (1 de março de 2013): 6–10. http://dx.doi.org/10.2174/13816128113198880008.

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9

Macé, Emilie, Gabriel Montaldo, Ivan Cohen, Michel Baulac, Mathias Fink e Mickael Tanter. "Functional ultrasound imaging of the brain". Nature Methods 8, n.º 8 (3 de julho de 2011): 662–64. http://dx.doi.org/10.1038/nmeth.1641.

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10

Rau, Richard, Pieter Kruizinga, Frits Mastik, Markus Belau, Nico de Jong, Johannes G. Bosch, Wolfgang Scheffer e Georg Maret. "3D functional ultrasound imaging of pigeons". NeuroImage 183 (dezembro de 2018): 469–77. http://dx.doi.org/10.1016/j.neuroimage.2018.08.014.

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11

Blomley, M. J. K., e R. J. Eckersley. "Functional ultrasound methods in oncological imaging". European Journal of Cancer 38, n.º 16 (novembro de 2002): 2108–15. http://dx.doi.org/10.1016/s0959-8049(02)00383-0.

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12

Mourad, Pierre D., Daniel A. Lazar, Francesco P. Curra, Brandt C. Mohr, Kathleen C. Andrus, Anthony M. Avellino, Lawrence D. McNutt, Lawrence A. Crum e Michel Kliot. "Ultrasound Accelerates Functional Recovery after Peripheral Nerve Damage". Neurosurgery 48, n.º 5 (1 de maio de 2001): 1136–41. http://dx.doi.org/10.1097/00006123-200105000-00035.

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Abstract OBJECTIVE Axonal injury in the peripheral nervous system is common, and often it is associated with severe long-term personal and societal costs. The objective of this study is to use an animal model to demonstrate that transcutaneous ultrasound can accelerate recovery from an axonotmetic injury. METHODS The sciatic nerve of adult male Lewis rats was crushed in the right midthigh to cause complete distal degeneration of axons yet maintain continuity of the nerve. Beginning 3 days after surgery, various transcutaneous ultrasound treatments or sham treatments were applied 3 days per week for 30 days to the crush site of rats that were randomly assigned to two groups. In the preliminary experiments, there were three animals in each ultrasound group and two control animals. In the final experiment, there were 22 animals in the ultrasound group and 20 animals in the control group. Recovery was assessed by use of a toe spread assay to quantify a return to normal foot function in the injured leg. Equipment included a hand-held transducer that emitted continuous-wave ultrasound. The most successful ultrasound protocol had a spatial peak, time-averaged intensity of 0.25 W/cm2 operated at 2.25 MHz for 1 minute per application. RESULTS Rats subjected to the most successful ultrasound protocol showed a statistically significant acceleration of foot function recovery starting 14 days after injury versus 18 days for the control group. Full recovery by the ultrasound group occurred before full recovery by the control group. CONCLUSION Transcutaneous ultrasound applied to an animal model of axonotmetic injury accelerated recovery. Future studies should focus on identification of the mechanism(s) by which ultrasound creates this effect, as a prelude to optimization of the protocol, demonstration of its safety, and its eventual application to humans.
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13

Bertholdt, C., M. Dap, M. Beaumont, J. Duan e O. Morel. "New insights into human functional ultrasound imaging". Placenta 117 (janeiro de 2022): 5–12. http://dx.doi.org/10.1016/j.placenta.2021.10.005.

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14

Qiaonong, Wen, Xu Shuang e Wan Suiren. "Ultrasound Image Deconvolution Based on Energy Functional". Journal of Nanoscience and Nanotechnology 16, n.º 7 (1 de julho de 2016): 6667–78. http://dx.doi.org/10.1166/jnn.2016.11363.

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Wen, Qiaonong, Shuang Xu e Suiren Wan. "Ultrasound Image Segmentation Based on Energy Functional". Journal of Nanoscience and Nanotechnology 16, n.º 9 (1 de setembro de 2016): 9359–70. http://dx.doi.org/10.1166/jnn.2016.12433.

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Tyurnikov, V. M., e A. O. Gushcha. "High-Intensity Focused Ultrasound in Functional Neurosurgery". Human Physiology 43, n.º 8 (dezembro de 2017): 916–21. http://dx.doi.org/10.1134/s036211971708014x.

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Bailao, L. A. "Ultrasound and Doppler in functional ovarian disturbances". Ultrasound in Medicine & Biology 29, n.º 5 (maio de 2003): S75. http://dx.doi.org/10.1016/s0301-5629(03)00334-x.

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18

Yeh, C. K., K. W. Ferrara e D. E. Kruse. "High-Resolution Functional Vascular Assessment With Ultrasound". IEEE Transactions on Medical Imaging 23, n.º 10 (outubro de 2004): 1263–75. http://dx.doi.org/10.1109/tmi.2004.834614.

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19

Moon, Sunho, Xiangming Xue, Vidisha Ganesh, Darpan Shukla, Benjamin C. Kreager, Qianqian Cai, Huaiyu Wu, Yong Zhu, Nitin Sharma e Xiaoning Jiang. "Ultrasound-Compatible Electrode for Functional Electrical Stimulation". Biomedicines 12, n.º 8 (2 de agosto de 2024): 1741. http://dx.doi.org/10.3390/biomedicines12081741.

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Functional electrical stimulation (FES) is a vital method in neurorehabilitation used to reanimate paralyzed muscles, enhance the size and strength of atrophied muscles, and reduce spasticity. FES often leads to increased muscle fatigue, necessitating careful monitoring of the patient’s response. Ultrasound (US) imaging has been utilized to provide valuable insights into FES-induced fatigue by assessing changes in muscle thickness, stiffness, and strain. Current commercial FES electrodes lack sufficient US transparency, hindering the observation of muscle activity beneath the skin where the electrodes are placed. US-compatible electrodes are essential for accurate imaging and optimal FES performance, especially given the spatial constraints of conventional US probes and the need to monitor muscle areas directly beneath the electrodes. This study introduces specially designed body-conforming US-compatible FES (US-FES) electrodes constructed with a silver nanowire/polydimethylsiloxane (AgNW/PDMS) composite. We compared the performance of our body-conforming US-FES electrode with a commercial hydrogel electrode. The findings revealed that our US-FES electrode exhibited comparable conductivity and performance to the commercial one. Furthermore, US compatibility was investigated through phantom and in vivo tests, showing significant compatibility even during FES, unlike the commercial electrode. The results indicated that US-FES electrodes hold significant promise for the real-time monitoring of muscle activity during FES in clinical rehabilitative applications.
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20

贺, 鑫媛. "Research Progress of Functional Ultrasound Imaging Technology". Journal of Clinical Personalized Medicine 03, n.º 04 (2024): 1597–604. https://doi.org/10.12677/jcpm.2024.34229.

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21

Yuan, Baohong, e Joshua Rychak. "Tumor Functional and Molecular Imaging Utilizing Ultrasound and Ultrasound-Mediated Optical Techniques". American Journal of Pathology 182, n.º 2 (fevereiro de 2013): 305–11. http://dx.doi.org/10.1016/j.ajpath.2012.07.036.

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22

Lin, Riqiang, Jiaming Zhang, Wen Gao, Xiatian Wang, Shengmiao Lv, Kwok-Ho Lam e Xiaojing Gong. "A Miniature Multi-Functional Photoacoustic Probe". Micromachines 14, n.º 6 (19 de junho de 2023): 1269. http://dx.doi.org/10.3390/mi14061269.

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Photoacoustic technology is a promising tool to provide morphological and functional information in biomedical research. To enhance the imaging efficiency, the reported photoacoustic probes have been designed coaxially involving complicated optical/acoustic prisms to bypass the opaque piezoelectric layer of ultrasound transducers, but this has led to bulky probes and has hindered the applications in limited space. Though the emergence of transparent piezoelectric materials helps to save effort on the coaxial design, the reported transparent ultrasound transducers were still bulky. In this work, a miniature photoacoustic probe with an outer diameter of 4 mm was developed, in which an acoustic stack was made with a combination of transparent piezoelectric material and a gradient-index lens as a backing layer. The transparent ultrasound transducer exhibited a high center frequency of ~47 MHz and a −6 dB bandwidth of 29.4%, which could be easily assembled with a pigtailed ferrule of a single-mode fiber. The multi-functional capability of the probe was successfully validated through experiments of fluid flow sensing and photoacoustic imaging.
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23

Solomatina, A. A., L. M. Mikhaleva, M. Yu Tyumentseva, O. V. Bratchikova, I. Z. Khamzin, E. A. Tumasyan, A. I. Gashimova e P. D. Ismayilova. "Morphological and functional features of the endometrium in patients before and after ovary-sparing surgery for benign ovarian tumors". Voprosy ginekologii, akušerstva i perinatologii 21, n.º 3 (2022): 45–52. http://dx.doi.org/10.20953/1726-1678-2022-3-45-52.

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Benign ovarian tumors (BOT) have a significant impact on fertility and are associated with infertility, which, in turn, relates to endometrial receptivity and depends on the ovarian status, forming the so-called endometriopathy. Objective. To study the morphological and functional features of the endometrium in patients of reproductive age before and after ovary-sparing surgery for BOT according to 2D and 3D ultrasounds. Patients and methods. The study included 145 patients who underwent surgery for BOT. Patients were divided into two groups. Group 1 included 75 patients with diminished ovarian reserve (OR), group 2 included 70 patients with normal OR. Diminished OR was defined as serum Anti-Müllerian hormone (AMH) level <1.1 ng/mL. Pelvic ultrasound (US) was performed in the mid-secretory phase before and 6–12 months after surgery. We measured endometrial thickness, endometrial pattern, visualization of basal and spiral arteries by 2D ultrasound, volume and volumetric blood flow in the endometrial and subendometrial regions by 3D ultrasound. Results. The analysis revealed endometrial dysfunction in patients with diminished OR before and after surgery, however there was a trend towards improvement in all the examined parameters after 12 months. In patients with normal OR before surgery, endometrial parameters did not differ from the population, but more persistent abnormalities were noted in the postoperative period. Conclusion. The 3D ultrasound technique provides an objective assessment of morphological and functional features of the endometrium and allows to identify markers of endometrial dysfunction. Key words: benign ovarian tumors, volumetric blood flow, ovarian reserve, 3D ultrasound, endometrium
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24

Alhakami, Anas Mohammed, Reem Abdullah Babkair, Ahmad Sahely e Shibili Nuhmani. "Effectiveness of therapeutic ultrasound on reducing pain intensity and functional disability in patients with plantar fasciitis: a systematic review of randomised controlled trials". PeerJ 12 (22 de março de 2024): e17147. http://dx.doi.org/10.7717/peerj.17147.

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Background Ultrasound therapy is one of the preferred conservative treatments for patients with plantar fasciitis. This study aims to evaluate the effectiveness of therapeutic ultrasound in decreasing pain intensity and improving functional disability in patients with plantar fasciitis. Methods Five randomised control trials (RCT) were selected based on an electronic search in PubMed, Trip Database and PEDro. To be included in the systematic review, the study should be an RCT which investigated the effectiveness of therapeutic ultrasound conducted in patients with plantar fasciitis with pain intensity and functional disability as outcome measures. Only studies published in peer-reviewed journals written in the English language were included. The quality of the selected studies was measured by the PEDro scale. Results All the included studies showed that ultrasound therapy is beneficial in reducing pain score and improving functional disability, except one study did not recommend using ultrasound therapy for plantar fasciitis. Moreover, regarding another outcome measure, two studies found that ultrasound therapy reduces thickness and tenderness in plantar fasciitis and improves static and dynamic balance. Conclusion After reviewing the five studies, this systematic review support using ultrasound therapy to decrease pain and improve functional disability in patients with plantar fasciitis. Study Registration https://osf.io/xftzy/.
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Ferronato, Letícia, Hemily Marega Cunha, Pâmela Maiara Machado, Gabriela dos Santos de Souza, Mirieli Denardi Limana e Núbia Carelli Pereira de Avelar. "Phisical modalities on the functional performance in knee osteoarthritis: a sytematic review". Fisioterapia em Movimento 30, n.º 3 (setembro de 2017): 607–23. http://dx.doi.org/10.1590/1980-5918.030.003.ar02.

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Abstract Introduction: Despite recent advances in the treatment of osteoarthritis (OA), few studies have evaluated the longitudinal effect of physical modalities in functional capacity in patients with knee OA. Thereby, since the physical components and pain can affect the functional performance of daily activities, the effect of these treatment’s form is still to be established. Objective: Evaluate the effectiveness of therapeutic ultrasound, electrical stimulation and phototherapy in the functional performance, in patients with knee osteoarthritis. Methods: Articles present in the PubMed, Lilacs, SciELO and PEDro’s databases were evaluated. The used keywords were “pulsed ultrasound therapy”, “ultrasound therapy”, “electric stimulation” and “low level laser therapy” in combination with “knee osteoarthritis”. Were included in this presented review, randomized clinical studies using ultrasound, electrical and laser stimulation in subjects with knee osteoarthritis. To evaluate the methodological quality of the selected studies, was used the PEDro’s scale. The dependent variables of the study were: pain, physical function, joint stiffness, life quality and functional performance. Results: 268 studies were found, of these, 41 studies met eligibility criteria and were classified for analysis in full. The used methodology in the studies varied widely, however, in most cases there was improvement in functional performance of individuals with knee OA, with the use of physical modalities, for the pulsed ultrasound, continuous ultrasound, electrical stimulation and laser resourses. Conclusion: The physical modalities used in the studies demonstrated improvement in functional performance of individuals with knee OA.
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Kenny, Jon-Émile S. "Functional Hemodynamic Monitoring With a Wireless Ultrasound Patch". Journal of Cardiothoracic and Vascular Anesthesia 35, n.º 5 (maio de 2021): 1509–15. http://dx.doi.org/10.1053/j.jvca.2021.01.040.

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Sieu, Lim-Anna, Antoine Bergel, Elodie Tiran, Thomas Deffieux, Mathieu Pernot, Jean-Luc Gennisson, Mickaël Tanter e Ivan Cohen. "EEG and functional ultrasound imaging in mobile rats". Nature Methods 12, n.º 9 (3 de agosto de 2015): 831–34. http://dx.doi.org/10.1038/nmeth.3506.

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Bzyl, Jessica, Wiltrud Lederle, Moritz Palmowski e Fabian Kiessling. "Molecular and functional ultrasound imaging of breast tumors". European Journal of Radiology 81 (setembro de 2012): S11—S12. http://dx.doi.org/10.1016/s0720-048x(12)70005-0.

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Mourad, Pierre D., Daniel A. Lazar, Francesco P. Curra, Brandt C. Mohr, Kathleen C. Andrus, Anthony M. Avellino, Lawrence D. McNutt, Lawrence A. Crum e Michel Kliot. "Ultrasound Accelerates Functional Recovery after Peripheral Nerve Damage". Neurosurgery 48, n.º 5 (maio de 2001): 1136–41. http://dx.doi.org/10.1227/00006123-200105000-00035.

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van Raaij, Martijn E., Liis Lindvere, Adrienne Dorr, Jianfei He, Bhupinder Sahota, F. Stuart Foster e Bojana Stefanovic. "Functional micro-ultrasound imaging of rodent cerebral hemodynamics". NeuroImage 58, n.º 1 (setembro de 2011): 100–108. http://dx.doi.org/10.1016/j.neuroimage.2011.05.088.

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Suzuki, A. H., J. Lee, S. G. Padilla e S. Martini. "Altering Functional Properties of Fats Using Power Ultrasound". Journal of Food Science 75, n.º 4 (24 de março de 2010): E208—E214. http://dx.doi.org/10.1111/j.1750-3841.2010.01572.x.

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Pulkkinen, Aki, Beat Werner, Ernst Martin e Kullervo Hynynen. "Numerical simulations of clinical focused ultrasound functional neurosurgery". Physics in Medicine and Biology 59, n.º 7 (12 de março de 2014): 1679–700. http://dx.doi.org/10.1088/0031-9155/59/7/1679.

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33

Anguluan, E., E. Kim e J. Kim. "Modulating brain functional connectivity using transcranial ultrasound stimulation". Brain Stimulation 12, n.º 2 (março de 2019): 566–67. http://dx.doi.org/10.1016/j.brs.2018.12.877.

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Martin, Ernst, Daniel Jeanmonod, Anne Morel, Eyal Zadicario e Beat Werner. "High-intensity focused ultrasound for noninvasive functional neurosurgery". Annals of Neurology 66, n.º 6 (dezembro de 2009): 858–61. http://dx.doi.org/10.1002/ana.21801.

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Zhang, Junhang, Chen Gong, Zihan Yang, Fan Wei, Xin Sun, Jie Ji, Yushun Zeng et al. "Ultrasound Flow Imaging Study on Rat Brain with Ultrasound and Light Stimulations". Bioengineering 11, n.º 2 (10 de fevereiro de 2024): 174. http://dx.doi.org/10.3390/bioengineering11020174.

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Functional ultrasound (fUS) flow imaging provides a non-invasive method for the in vivo study of cerebral blood flow and neural activity. This study used functional flow imaging to investigate rat brain’s response to ultrasound and colored-light stimuli. Male Long-Evan rats were exposed to direct full-field strobe flashes light and ultrasound stimulation to their retinas, while brain activity was measured using high-frequency ultrasound imaging. Our study found that light stimuli, particularly blue light, elicited strong responses in the visual cortex and lateral geniculate nucleus (LGN), as evidenced by changes in cerebral blood volume (CBV). In contrast, ultrasound stimulation elicited responses undetectable with fUS flow imaging, although these were observable when directly measuring the brain’s electrical signals. These findings suggest that fUS flow imaging can effectively differentiate neural responses to visual stimuli, with potential applications in understanding visual processing and developing new diagnostic tools.
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Akram, Saba, Aasma Ashraf, Zainab Zahur, Aniqua Saleem, Safia Ashraf e Nadia Nazir. "Characteristics of Ovarian Cysts Observed in Doppler Ultrasound". Pakistan Journal of Medical and Health Sciences 15, n.º 10 (30 de outubro de 2021): 3304–6. http://dx.doi.org/10.53350/pjmhs2115103304.

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Background: Ovarian cysts known as ovarian masses, are commonly found incidentally in asymptomatic women. Ovarian cancer is the 7th most frequent cancer in women worldwide, as well as the eighth leading cause of cancer death. Ultrasonography is the principal imaging technique for confirming the mass ovarian origin and determining whether the mass is benign or malignant. Method: This descriptive cross sectional study was conducted from 15 June to December 2019 in the Radiology Department of Avicenna Medical College. A total of 90 ultrasounds undertaken at the Gynecological Ultrasound Unit. A total of 32 patients with functioning ovarian cysts were included. A total of 46 individuals with benign tumors and 9 patients with malignant cysts were included in the control group. The remaining patients were not followed up on and were treated at a different center. The majority of the patients had issues with their menstrual cycle and pain. Results: The mean age of the patients was 35.6+9.16. In functioning ovarian cysts, benign tumors & ovarian tumors. The functioning ovarian cysts had a mean size of 40.8 mm +16.35 mm. Differences were significant found between1this group & other1two groups: A mean size of 61.75 +65.5; P, 0.001 was seen for non-functional benign ovarian disease; and the average size of malignant cysts was 85.9 +50.6; P = 0.001. Out of 32 functional1ovarian cysts, 22 were found by ultrasonography, 8.0 were not identified and 2.0 cases were1diagnosed ultra-sonographically as functional ovarian cysts but histologically revealed to be benign ovarian cysts (non-functional). The sensitivity of color Doppler ultrasound was determined to be 82.0%. Conclusion: The study's findings revealed that ultrasound had an 82 percent sensitivity in diagnosing ovarian masses, increasing its accuracy. As a result, ultrasonography appears to be the first modality of choice in the examination of any woman suspected of having an ovarian tumor. Also, to rule out the need for unnecessarily surgical procedures in benign lesions. Keywords: Ovarian Cysts, cancer, ultrasound
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Arief Efendi e Nurul Halimah. "THE EFFECT OF COMBINED ULTRASOUND AND MC KENZIE ON IMPROVING FUNCTIONAL ABILITY IN PATIENTS WITH MYOGENIC LOW BACK PAIN". STAND : Journal Sports Teaching and Development 4, n.º 1 (16 de julho de 2023): 68–72. http://dx.doi.org/10.36456/j-stand.v4i1.7785.

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Low back pain is a musculoskeletal disorder with signs of pain in the area around the lower back, the incidence is mostly myogenic low back pain, it increases with age. Physiotherapy interventions used to improve functional ability with a combination of ultrasound and mc kenzie. The purpose of this study was to determine the effect of a combination of ultrasound and mc kenzie on improving functional abilities in patients with myogenic low back pain. This research design uses a type of quasi-experimental with a one group pretest and posttest approach, this study has 20 respondents using a sampling technique, namely purposive sampling. The effect of the combination of ultrasound and mc kenzie on functional ability in myogenic low back pain patients with a p-value = 0.001 (p <0.05). Based on the results of this study, it is stated that the combination of ultrasound and mc kenzie can improve functional ability in myogenic Low Back Pain patients performed 2 times a week for 4 weeks.
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Silișteanu, Andrei-Emanuel, e Juliánna Szakács. "Study on the effects of the use of therapeutic ultrasound in the treatment of osteoarticular diseases". Balneo and PRM Research Journal, Vol.13, no.1 (19 de março de 2022): 482. http://dx.doi.org/10.12680/balneo.2022.482.

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Introduction. The use of therapeutic ultrasounds is a method that proved its efficiency in articu-lar and periarticular pathology, in the subacute and chronic stages. The biological effects of the ultrasound use are determined by their interaction with the cellular structures whereas the re-sults depend on the used parameters. The purpose of the survey is to evaluate / identify the ef-fects of using ultrasounds in the treatment of musculoskeletal conditions (lumbar discopathy), knee osteoarthritis). Material and method. The survey was conducted on an outpatient basis in a period of 7 months and it is of the longitudinal type. It included 151 patients diagnosed with low back pain and knee osteoarthritis. The evaluated parameters were: pain, functional skills, articu-lar rigidity and the quality of life. Results. The effects of the use of ultrasounds is found in the decrease of pain, the stiffness of the joints and the contracture of the muscles, as shown by the re-sults of several surveys. Our survey proves that the use of ultrasounds decreases pain and in-creases the functional skills, it influences the physical function more obviously in patients with knee osteoarthritis, which is an aspect found in others surveys. Discussion. The use of a complex ultrasound treatment (in the pulsed way to avoid thermal effects) and kinesiotherapy enabled in our research the decrease of the pain and of the rigidity in the joints, the increase of the function-al skills and the quality of life, whereas these obtained results are in accordance with those of others surveys. Conclusions. The use of the therapeutic ultrasounds can have the following ef-fects: the decrease of the pain and of the joint rigidity, the improvement of the physical capacity for daily activities and the improvement of the quality of life. The use of low intensity ultra-sounds can determine biological effects with actions for a short period or for an average one. Keywords: therapeutic ultrasound, treatment, osteoarticular diseases, quality of life
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Oppersma, Eline, Nima Hatam, Jonne Doorduin, Johannes G. van der Hoeven, Gernot Marx, Andreas Goetzenich, Sebastian Fritsch, Leo M. A. Heunks e Christian S. Bruells. "Functional assessment of the diaphragm by speckle tracking ultrasound during inspiratory loading". Journal of Applied Physiology 123, n.º 5 (1 de novembro de 2017): 1063–70. http://dx.doi.org/10.1152/japplphysiol.00095.2017.

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Assessment of diaphragmatic effort is challenging, especially in critically ill patients in the phase of weaning. Fractional thickening during inspiration assessed by ultrasound has been used to estimate diaphragm effort. It is unknown whether more sophisticated ultrasound techniques such as speckle tracking are superior in the quantification of inspiratory effort. This study evaluates the validity of speckle tracking ultrasound to quantify diaphragm contractility. Thirteen healthy volunteers underwent a randomized stepwise threshold loading protocol of 0–50% of the maximal inspiratory pressure. Electric activity of the diaphragm and transdiaphragmatic pressures were recorded. Speckle tracking ultrasound was used to assess strain and strain rate as measures of diaphragm tissue deformation and deformation velocity, respectively. Fractional thickening was assessed by measurement of diaphragm thickness at end-inspiration and end-expiration. Strain and strain rate increased with progressive loading of the diaphragm. Both strain and strain rate were highly correlated to transdiaphragmatic pressure (strain r2 = 0.72; strain rate r2 = 0.80) and diaphragm electric activity (strain r2 = 0.60; strain rate r2 = 0.66). We conclude that speckle tracking ultrasound is superior to conventional ultrasound techniques to estimate diaphragm contractility under inspiratory threshold loading. NEW & NOTEWORTHY Transdiaphragmatic pressure using esophageal and gastric balloons is the gold standard to assess diaphragm effort. However, this technique is invasive and requires expertise, and the interpretation may be complex. We report that speckle tracking ultrasound can be used to detect stepwise increases in diaphragmatic effort. Strain and strain rate were highly correlated with transdiaphragmatic pressure, and therefore, diaphragm electric activity and speckle tracking might serve as reliable tools to quantify diaphragm effort in the future.
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Криштопова, М. А., Л. Г. Петрова e В. Н. Гирса. "The Method of Ultrasound Biofeedback in the Treatment of Persistent Forms of Functional Dysphonia". Оториноларингология. Восточная Европа, n.º 2 (16 de julho de 2020): 130–40. http://dx.doi.org/10.34883/pi.2020.2.2.009.

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Цель исследования. Повысить эффективность комплексного лечения пациентов с функциональными дисфониями методом визуальной ультразвуковой биологической обратной связи.Материалы и методы. Проспективное обсервационное исследование проводилось пациентам с функциональной дисфонией/афонией (n=91). Основными видами лечения были комплексное медикаментозное лечение и фонопедия (G1, n=45) или комплексное медикаментозное лечение и фонопедия с методом ультразвуковой биологической обратной связи (G2, n=46).Результаты. Более быстрое и стойкое восстановление голоса наблюдалось в группе пациентов, получавших комплексное медикаментозное лечение и фонопедию с методом ультразвуковой биологической обратной связи, по сравнению с группой пациентов, получавших комплексное медикаментозное лечение и фонопедию без ультразвуковой биологической обратной связи (p<0,005).Заключение. Фонопедическое лечение с биологической обратной связью является эффективным методом лечения функциональной дисфонии. The purpose of the study is to improve treatment of patients with functional dysphonia by using the method of ultrasound visual biofeedback.Materials and methods. Prospective observational study was performed for patients with functional dysphonia/aphonia (n=91). Medication therapy and oropharyngeal muscle exercisetherapy without ultrasound biofeedback (G1, n=45) or oropharyngeal muscle exercise therapy with ultrasound biofeedback (G2, n=46) were used.Results. The group of patients receiving medication therapy and oropharyngeal muscle exercise therapy with ultrasound biofeedback compared to the group of patients without ultrasound biological feedback had significantly higher functional results (p<0.005).Conclusion. Oropharyngeal muscle exercise therapy with ultrasound biofeedback is an effective treatment tool for functional dysphonia.
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Moser, David, Eyal Zadicario, Gilat Schiff e Daniel Jeanmonod. "Measurement of targeting accuracy in focused ultrasound functional neurosurgery". Neurosurgical Focus 32, n.º 1 (janeiro de 2012): E2. http://dx.doi.org/10.3171/2011.10.focus11246.

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The object of this study was to describe a method of measuring targeting accuracy in functional neurosurgery using MR imaging and the Stereotactic Atlas of the Human Thalamus and Basal Ganglia. This method should be useful for any functional procedure using these tools or similar ones, and is described here in the specific context of focused ultrasound surgery. The authors describe the atlas coordinate system used, the different relevant targeting and accuracy definitions, the tools used, the intraoperative target determination, the postoperative target reconstructions, and the calculation of the therapeutic lesion volume. The proposed method has been applied to the specific situation of measuring targeting accuracy in focused ultrasound functional neurosurgery. The authors found mean absolute global targeting accuracies between 0.54 and 0.72 mm (SDs between 0.34 and 0.42 mm), with 85% of measured coordinates within 1 mm. The proposed method may be particularly useful in the context of functional neurosurgical procedures implying therapeutic ablations, be they through radiofrequency, focused ultrasound, or any other technique. This method allows an ongoing control of the targeting precision, a basic requirement in any functional neurosurgical procedure.
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Rakan Saleh Alkhalifah. "Ultrasound Technology And Biomaterials For Precise Drug Therapy". Journal of Namibian Studies : History Politics Culture 33 (15 de janeiro de 2023): 1–11. http://dx.doi.org/10.59670/rj2ega72.

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Advanced ultrasound technology and functional biomaterials can be used to achieve precision drug therapy in different aspects such as dose, space, and/or time. At present, many physical or chemical technologies and preparations, such as ultrasound, light, magnetism, and enzyme, have been used to prepare a variety of functional biomaterials and trigger precise drug delivery. Notably, ultrasound provides a convenient and robust technology for drug triggering and precision therapy and is increasingly being studied and applied. At present, the ultrasound system mainly triggers and realizes precise drug treatment through sonophoresis and sonoopermeation (including inorganic-based nanoparticles, microbubbles, nanobubbles, liposomes, micelles, micro-nanomotors, etc.). This review first introduces the classification of ultrasound and related physical properties involving precision drug treatment, and then systematically discusses the realization of drug precision treatment through sonophoresis and sonopermeation. In particular, key information such as effective ultrasonic intensity and frequency parameter range, types of loaded drugs, systematic therapeutic effect, and so on for precision therapy with an advanced combination of ultrasonic technology and various biological materials were expounded and summarized. In addition, relevant clinical opportunities and challenges are described. Finally, the development and application of ultrasound-functional biomaterials for drug precision therapy are prospected.
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Hou, Riying. "Postoperative Nursing and Functional Rehabilitation of Ultrasound Diagnosis of Lower Rotator Cuff Injury". Scanning 2022 (28 de agosto de 2022): 1–7. http://dx.doi.org/10.1155/2022/8319082.

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In order to explore the postoperative nursing effect and functional rehabilitation of rotator cuff repair under ultrasound diagnosis, a method of nursing and rehabilitation functional training for athletes’ wrist injury under the assistance of microscopic B-ultrasound was proposed. This study retrospectively analyzed the therapeutic effect of tendon anastomosis in 237 patients with wrist tendon injury, adopted nursing measures such as health education and functional exercise, and observed its clinical effect. The results showed that after 3-6 months of follow-up, all patients had satisfactory recovery of tendon function. Of these, 132 patients recovered well. 84 patients recovered well. The excellent and good rate of patients was 91%. Ultrasound diagnosis of rotator cuff repair combined with functional exercise promotes good recovery of shoulder joint function in patients.
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Wibawa, Ari, Ni Wayan Tianing, Gede Parta Kinandana e Ni Komang AYu Juniantari. "THE COMPARISON OF INTERVENTION OF ULTRASOUND AND MUSCLE ENERGY TECHNIQUE WITH ULTRASOUND AND MCKENZIE EXERCISE INTERVENTION ON INCREASING FUNCTIONAL ABILITY IN NON-SPECIFIC LOW BACK PAIN". Majalah Ilmiah Fisioterapi Indonesia 6, n.º 2 (15 de maio de 2018): 55. http://dx.doi.org/10.24843/mifi.2018.v06.i02.p13.

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This study aims to compare ultrasound interventions and muscle energy techniques more effective than ultrasound and McKenzie exercise in improving functional ability in non-specific low back pain cases. The test used is a modified oswestry low back pain disability questionnaire to measure functional pain. Using experimental design with pre-test and post-test group design involved a sample of 32 people divided into 2 groups. Group 1 with ultrasound treatment and muscle energy technique and group 2 with ultrasound treatment and Mckenzie exercise. Hypothesis test results using the independent sample t-test obtained results p = 0,000 with a mean difference in group 1 22,85 (SB 4,348) while group 2 obtained a mean difference of 12,86 (SB 2,797). These results showed that there was a significant difference in the reduction of significant non-specific LBP functional pain between the treatment groups of the muscle energy technique and the McKenzie exercise treatment group.Keywords: non-specific low back pain, modified oswestry low back pain, disability questionnaire, ultrasound, muscle energy technique, mckenzie exercise
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45

Antsaklis, Panagiotis, e Sebija Izetbegovic. "Functional Test for Fetal Brain: The Role of KANET Test". Donald School Journal of Ultrasound in Obstetrics and Gynecology 7, n.º 4 (2013): 385–99. http://dx.doi.org/10.5005/jp-journals-10009-1309.

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ABSTRACT Defining normal and abnormal fetal neurological function in utero in order to better predict antenatally which fetuses are at risk for adverse neurological outcome has remained a great challenge in perinatal medicine. Fetal behavioral patterns have been considered as indicators of fetal brain development. It has been suggested that the assessment of fetal behavior in different periods of gestation may make possible the distinction between normal and abnormal brain development. Advances in ultrasound technology and particularly the introduction of real time four-dimensional (4D) ultrasonography, allowed direct observation of in utero life and offered a new insight for the assessment of fetal behavior. Fetal behavioral movements, the full range of facial expressions and mobility of fetal upper and lower extremities and fingers can be clearly visualized with 4D ultrasound. A new scoring system for the assessment of fetal neurobehavior based on prenatal assessment of the fetus with 4D sonography has been developed based on the same technique that neonatologists assess newborns during the first days of their postnatal life. This overview focuses on the study of fetal behavior and neurological assessment with 4D ultrasound. How to cite this article Antsaklis P, Kurjak A, Izetbegovic S. Functional Test for Fetal Brain: The Role of KANET Test. Donald School J Ultrasound Obstet Gynecol 2013;7(4):385-399.
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46

Ashfaq, Alweera. "Ultrasound-assisted Extraction of Plant-Based Proteins: A Novel Technique". Indian Journal of Pure & Applied Biosciences 9, n.º 3 (30 de junho de 2021): 145–50. http://dx.doi.org/10.18782/2582-2845.8676.

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Ultrasound has been explored in recent times by researchers and food processing industries due to its capacity to increase extraction efficacy by enhancing mass transfer and rupturing cells due to acoustic cavitation. In protein extraction ultrasound treatment is generally used as a pretreatment in combination with the traditional method of extraction as it breaks the cell wall and improves the extractability. Ultrasound treatment not only improves the extraction rate but can also modify the functional properties of the protein product. The rate and yield of protein extraction depend on the operating conditions like power density of ultrasound, pulse, duration of ultrasonication, solid to solvent ratio, temperature, extraction solvent, pH, and so on. The current paper aims to present the impact of incorporating ultrasound technology with traditional technologies on the yield and functional properties of protein extraction from plant sources.
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Zhang, Minjian, Bo Li, Yafei Liu, Rongyu Tang, Yiran Lang, Qiang Huang e Jiping He. "Different Modes of Low-Frequency Focused Ultrasound-Mediated Attenuation of Epilepsy Based on the Topological Theory". Micromachines 12, n.º 8 (23 de agosto de 2021): 1001. http://dx.doi.org/10.3390/mi12081001.

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Epilepsy is common brain dysfunction, where abnormal synchronized activities can be observed across multiple brain regions. Low-frequency focused pulsed ultrasound has been proven to modulate the epileptic brain network. In this study, we used two modes of low-intensity focused ultrasound (pulsed-wave and continuous-wave) to sonicate the brains of KA-induced epileptic rats, analyzed the EEG functional brain connections to explore their respective effect on the epileptic brain network, and discuss the mechanism of ultrasound neuromodulation. By comparing the brain network characteristics before and after sonication, we found that two modes of ultrasound both significantly affected the functional brain network, especially in the low-frequency band below 12 Hz. After two modes of sonication, the power spectral density of the EEG signals and the connection strength of the brain network were significantly reduced, but there was no significant difference between the two modes. Our results indicated that the ultrasound neuromodulation could effectively regulate the epileptic brain connections. The ultrasound-mediated attenuation of epilepsy was independent of modes of ultrasound.
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48

Mroczek, Karolina, Bogdan Saletnik, Marcin Bajcar, Aneta Saletnik, Czesław Puchalski e Grzegorz Zaguła. "Ultrasound-Assisted Extraction as a Technique for Preparing Improved Infusions as Functional Beverage Bases". Applied Sciences 13, n.º 20 (17 de outubro de 2023): 11392. http://dx.doi.org/10.3390/app132011392.

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Right after water, tea is one of the most popular beverages in the world. The composition of a tea drink is determined by, among other things: the degree of fermentation and the fineness of the tea leaves, as well as the brewing time and temperature. The purpose of this study was to verify the hypothesis that the extraction of selected elements from dried tea during infusion preparation was improved by using ultrasound under laboratory conditions. The effect of increasing the extraction time was also analyzed. The effectiveness of ultrasound was evaluated by measuring the content of selected elements in the extract of teas that were treated with ultrasound compared to a control group. The effectiveness of the application of ultrasound was evaluated by measuring the content of individual elements at intervals of 1 min, 5 min and 10 min comparing the application of ultrasound with the classical technique of tea brewing. In addition, the results were related to measurements of the amounts of overall concentrations of selected ions after the dried tea mineralization procedure. Samples of extracts and mineralizates were analyzed for elemental composition using an ICP-OES iCAP Dual 6500 Thermo® spectrometer. The use of ultrasound was shown to have a positive effect on the extraction process, and the efficiency of the process depended on the tea variety and the extraction time. The percentage of extraction relative to the results of the total amount of extracted ions was also calculated. Analyzing the effect of ultrasound on the leaching of minerals from tea leaves during infusion preparation is another step toward optimizing the tea brewing extraction process and a way to improve the nutritional value of tea infusions as a functional beverage base. The application of ultrasound in the extraction process of tea infusions may be a good solution to support traditional methods of extracting infusions for both research and technological purposes.
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Криштопова, М. А., Л. Г. Петрова e В. Н. Гирса. "The Role of Laryngeal Ultrasound in the Assessment and Treatment of Functional Dysphonia". Оториноларингология. Восточная Европа, n.º 1 (8 de abril de 2020): 51–58. http://dx.doi.org/10.34883/pi.2020.10.1.034.

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Цель исследования: повышение эффективности диагностики и объективизации эффекта комплексного лечения пациентов с функциональными дисфониями с помощью УЗИ гортани. Материалы и методы: исследование гортани с помощью УЗИ проводилось здоровым лицам без дисфонии (n10) и пациентам с функциональной дисфонией/афонией (n20). Основными видами лечения пациентов были комплексное медикаментозное лечение и фонопедия (G1, n10) или фонопедия с ультразвуковой биологической обратной связью (G2, n10). Результаты: УЗИ гортани в B-режиме и в режиме доплерографии с фонаторными пробами позволяет визуализировать нарушение координации работы мышц гортани в виде напряжения вестибулярного отдела гортани, ограничения подвижности, наличия неполного смыкания и отсутствие вибрации голосовых складок при фонации. Более быстрое и стойкое восстановление голоса наблюдалось в группе пациентов, получавших комплексное медикаментозное лечение и фонопедию с ультразвуковой биологической обратной связью, по сравнению с группой пациентов, получавших комплексное медикаментозное лечение и фонопедию без ультразвуковой биологической обратной связи (p0,005). Заключение: УЗИ гортани в B-режиме и режиме доплерографии с фонаторными пробами позволяет глубже понять патофизиологические процессы функциональной дисфонии. Фонопедическое лечение с биологической обратной связью является эффективным методом лечения функциональной дисфонии. The purpose of the study is to improve diagnosis and treatment of patients with functional dysphonia by using ultrasound of the larynx. Materials and methods. Larynx ultrasonography was performed to healthy people without dysphonia (n10) and patients with functional dysphonia/aphonia (n20). Complex medication therapy and oropharyngeal muscle exercise therapy without ultrasound biofeedback (G1, n10) or oropharyngeal muscle exercise therapy with ultrasound biofeedback (G2, n10) were used. Results. Larynx ultrasonography is a minimally invasive, easily reproducible, and inexpensive method of laryngeal examining. It may become a perfect tool for functional dysphonia identification with its later monitoring. The group of patients receiving complex medication therapy and oropharyngeal muscle exercise therapy with ultrasound biofeedback compared to the group of patients without ultrasound biological feedback had significantly higher functional results (p0.005). Conclusion. Larynx ultrasonography is a perfect tool for understanding the pathophysiology of functional dysphonia. Oropharyngeal muscle exercise therapy with ultrasound biofeedback is an effective treatment tool for functional dysphonia.
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Shi, Ji, Ye Zhang, Bing Yao, Peixin Sun, Yuanyuan Hao, Haozhe Piao e Xi Zhao. "Application of Multiparametric Intraoperative Ultrasound in Glioma Surgery". BioMed Research International 2021 (16 de abril de 2021): 1–18. http://dx.doi.org/10.1155/2021/6651726.

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Gliomas are the most invasive and fatal primary malignancy of the central nervous system that have poor prognosis, with maximal safe resection representing the gold standard for surgical treatment. To achieve gross total resection (GTR), neurosurgery relies heavily on generating continuous, real-time, intraoperative glioma descriptions based on image guidance. Given the limitations of currently available equipment, developing a real-time image-guided resection technique that provides reliable functional and anatomical information during intraoperative settings is imperative. Nowadays, the application of intraoperative ultrasound (IOUS) has been shown to improve resection rates and maximize brain function preservation. IOUS, which presents an attractive option due to its low cost, minimal operational flow interruptions, and lack of radiation exposure, is able to provide real-time localization and accurate tumor size and shape descriptions while helping distinguish residual tumors and addressing brain shift. Moreover, the application of new advancements in ultrasound technology, such as contrast-enhanced ultrasound, three-dimensional ultrasound, navigable ultrasound, ultrasound elastography, and functional ultrasound, could help to achieve GTR during glioma surgery. The current review describes current advancements in ultrasound technology and evaluates the role and limitation of IOUS in glioma surgery.
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