Teses / dissertações sobre o tema "Emergence de l'âge adulte"
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Pithon, Lucas. "Twitch.tv : de la consommation de contenu à la recherche de contenance ? : exploration des enjeux psychologiques des jeunes adultes spectateurs d’un réseau interactif de diffusion de contenu en direct". Electronic Thesis or Diss., Angers, 2024. http://www.theses.fr/2024ANGE0039.
Texto completo da fonteThis thesis examines how Twitch.tv, a live streaming platform, fits into the context of hypermodernity and influences the passage to adulthood. In a world where traditional points of reference are shifting under the impact of social and technological transformations, this research analyzes how young adults invest in live streams to find narcissistic support, and weave new forms of social ties. Combining quantitative and qualitative approaches, the study reveals that Twitch.tv becomes a place of re-enchantment and identity construction, offering both narcissistic support and a framework for collective engagement. This thesis sheds new light on contemporary psychosocial dynamics, illustrating the central role of the digital in the complex process of becoming an adult in the hypermodern age
Guenin, Didier. "En chemin vers l'âge adulte". Paris 7, 2005. http://www.theses.fr/2005PA070002.
Texto completo da fonteCompared to the reports written by ethnologists on traditional societies, French child living at the beginning of XXlst century is educated in a cocoon and set aside from adults' world. A survey on childhood fantasy worlds (Disney, Pokemons, Harry Potter) combined with the analysis of 3 field studies (child at school, child in public spaces, child at home) deliver a fair approach of this question. Analysed through the concept of "social distance", developed on purpose, the surveys and studied fields reveal that child is not separated from real world but protected and kept at large distance by a dynamic link. The formative way powered by a child to prepare himself to enter society and learn social behaviours and rituals create distance relationship between the child and the world. The "child of distance" is also the "child of love" who experiences the strength of love in family ; he is the "connected child" that knows how to build a discontinue relationship with the external world and the others. He is also a "creative person", creating himself and the future world. A child does not enter adult world, h becomes an adult while becoming himself
Cornic, Françoise. "Devenir à l'âge adulte des adolescents catatoniques". Paris 6, 2011. http://www.theses.fr/2011PA066132.
Texto completo da fonteNeault, Sylvie. "La métamémoire à l'âge adulte : l'influence du sexe et de l'âge des sujets". Thèse, Université du Québec à Trois-Rivières, 1988. http://depot-e.uqtr.ca/5774/1/000569490.pdf.
Texto completo da fonteGrèze, Victoria. "Cancers dans l'enfance et fertilité à l'âge adulte". Thesis, Université Clermont Auvergne (2017-2020), 2019. http://www.theses.fr/2019CLFAS011.
Texto completo da fonteAdvances in the treatment of childhood and adolescent cancers have led to real improvements as long-term survival is now over 80%. As a result, quality of life of these future adults is a major concern for the professionals involved in the care of these patients. Our work focuses on pubertal development and fertility, through epidemiological research and transfer research, in childhood cancer survivor.Concerning the "epidemiological research", female pubertal development and fertility were studied using the L.E.A cohort (Childhood and Adolescent Leukemias), which collects data about the outcome of patients treated for childhood leukemia. Although it is more important in women who received hematopoietic stem cell transplantation and/or relapsed, gonadotoxicity also affects those who received only first-line chemotherapy.In parallel, access to fertility preservation for adolescents and young adults treated for malignant diseases in Auvergne was analyzed. Boys benefit more from fertility consultation and preservation of their fertility. Progress should be made thanks the creation of clinico-biological platforms such as PREFERA (PREservation FERtilité Auvergne), which ensure better coordination between the different teams that support these patients.Concerning the "transfer research", we addressed the cryopreservation of gonadal tissues, only option for prepubertal children in particular, but with a potential risk of neoplastic cells reintroduction in case of future use. We developed sensitive and specific techniques of residual disease detection for two solid pediatric tumors whose current treatments are potentially sterilizing: neuroblastoma and Ewing's tumor. The interest is to have a diagnostic test usable for adults cured of these cancers, whose fertility has been compromised by the treatments and who have benefited from ovarian or testicular tissue cryopreservation
Soguel, Alexander Ludivine. "Gain de poids à l'âge adulte et densité mammaire". Master's thesis, Université Laval, 2015. http://hdl.handle.net/20.500.11794/27240.
Texto completo da fonteL’adiposité est un facteur de risque connu pour le cancer du sein et le gain de poids à l’âge adulte semble l’être également. Au niveau mammaire, le tissu adipeux peut être étudié au travers des mesures de densité. En effet, la zone non-dense reflète le gras mammaire et le pourcentage de densité, l’un des plus importants facteurs de risque pour le cancer du sein, reflète la proportion de tissu fibroglandulaire. Le premier objectif de ce mémoire était d’évaluer, chez 1435 femmes recrutées lors d’une mammographie de dépistage, l’association entre le gain de poids à l’âge adulte et trois paramètres de mesure de densité mammaire : le pourcentage de densité et les zones dense et non-dense en valeurs absolues. Le second objectif était de présenter un texte de synthèse et de discussion portant sur les interrelations entre l’adiposité, la densité mammaire et le risque de cancer du sein.
Adiposity is a known risk factor for breast cancer and weight gain during adulthood also seems to play a role. In the breast, adipose tissue can be studied through breast density features. Indeed, absolute non-dense area reflects breast fat and percent density, one of the strongest risk factor for breast cancer, reflects the proportion of fibroglandular tissue. The first objective of this dissertation was to evaluate the association between weight gain during adulthood and three density features: percent density, absolute dense and non-dense areas, among 1435 women recruited at screening mammography. The second objective was to present a consolidated text of the interrelation between adiposity, breast density and breast cancer risk and to discuss it in an epidemiological and biological point of view.
Murray, Guylaine. "Suivi de la fonction pulmonaire de l'enfance à l'âge adulte". Thèse, Université du Québec à Trois-Rivières, 2010. http://depot-e.uqtr.ca/1960/1/030154082.pdf.
Texto completo da fonteFortier, Stéphanie. "Agression sexuelle à l'enfance, motivations sexuelles à l'âge adulte et conduites sexuelles extradyadiques". Doctoral thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/36275.
Texto completo da fonteSafwan, Zaiter Hasan. "Le marqueur de sénescence p16Ink4a dans le développement, l'âge adulte et le vieillissement". Electronic Thesis or Diss., Université Côte d'Azur, 2023. http://www.theses.fr/2023COAZ6029.
Texto completo da fonteAging is a biological feature that is characterized by gradual degeneration of function of cells, tissues, organs, or an intact organism due to accumulation of environmental factors and stresses with time. Several factors have been attributed to aging such as oxidative stress, telomere shortening, DNA damage and most importantly, the deposit of senescent cells (SnCs). These are irreversibly mitotically inactive, yet metabolically active cells. The reason underlying their senescence lies within the extrinsic and the intrinsic arms. The extrinsic arm is mainly characterized by the expression and the secretory profile known as the senescence associated secretory phenotype (SASP). The intrinsic arm results from the impact of several genes meant to regulate the cell cycle, such as the tumor suppressor genes p16Ink4a (p16), p19ARF (p19) and p21. P16 is a tumor suppressor and cell cycle regulator that has been linked to aging and senescence. Extensive research has revealed that p16 expression is significantly increased in SnCs, as well as during natural aging or age-related pathologies. Based on this fact, p16 is considered as a specific biomarker for identifying SnCs and aging. Whilst a potential role of p19 and p21 has been demonstrated in embryonic development, yet p16 has been less well documented. To investigate p16's potential role in development, we conducted a developmental expression study of p16, beside the tumor suppressors p19 and p21, and examined their RNA expression in the brain, heart, liver, and kidney of mice at embryonic, postnatal, adult, and old ages. Moreover, immunohistochemistry (IHC) was used to examine p16 expression at the protein level. We found that p16 expression was highly dynamic in all organs during embryonic and postnatal stages, and it was significantly more upregulated in old mice compared to p19 and p21. Furthermore, we found that p16 mRNA and protein were more prevalent in liver endothelial cells (ECs) than parenchymal cells in old mice. These findings point to a possible role for p16 in embryonic development, as well as a potential selective role for p16 in liver ECs.Therefore, we aimed at better understanding the role of p16 in biological processes of liver ECs Hence, we used small hairpin (shRNA) constructs and a p16 cDNA-GFP vector transduced via a lentivirus, to knock-down and over-express p16 in-vitro, in order to assess the loss and gain of function in two types of liver ECs, CD31+ vascular ECs and CD146+ sinusoidal endothelial cells (LSECs). Cells were isolated from the liver through magnetic activated cells sorting (MACS) assay using a magnetic bead-attached monoclonal antibodies against CD31 and CD146 surface markers. Non-coding sequence and an empty-GFP vector transduced cells were used as a control for shRNA and p16-GFP transduced cells, respectively
Li, Na. "Programmation postnatale du risque cardio-métabolique : effets d'une restriction calorique modérée à l'âge adulte". Thesis, Dijon, 2016. http://www.theses.fr/2016DIJOS017/document.
Texto completo da fontePostnatal overfeeding (PNOF) in rodents induces early programming of cardio-metabolic risk. Our aim was to determine if a moderate diet restriction could restore cardio-metabolic alterations induced by PNOF.Immediately after birth, litters of C57BL/6 mice were either maintained at 9 (normal litter, NL), or reduced to 3 (small litter, SL) to induce PNOF. At weaning, all mice received a standard diet ad libitum (AL). At 6 month of age, half of the NL and SL mice were assigned to a moderate 20% calorie restriction (CR: NLCR, SLCR) for one month, while the other mice continued to eat AL (AL: NLAL, SLAL). Glucose and insulin tolerance tests, cardiac function (echocardiography), body composition (Echo-MRI), cardiac sensitivity to ischemia-reperfusion injury, mitochondrial function, reactive oxygen species (ROS) generation (EPR spectroscopy) and insulin signaling were assessed before and/or after one month of CR.Adult SL mice presented overweight, fat accumulation, hyperleptinemia, glucose intolerance, insulin resistance and decreased left ventricular ejection fraction (LVEF). After one month of moderate CR, body weight of SLCR was normalized to this of NLAL however their fat mass and leptinemia were not decreased. Glucose metabolism was improved and LVEF was increased In SLCR. After 30 min of global ischemia, hearts isolated from SLCR mice showed better recovery and smaller infarct size than this of others groups. CR increased the cardiac mitochondrial respiratory rate in SLCR mice whereas cardiac ROS production was significantly decreased in SLCR mice. Insulin signaling in heart was affected neither by PNOF nor by CR. Intriguingly, no difference was observed in NLCR mice for most of the parameters investigated.Our results confirmed the programming of early overfeeding on metabolic and cardiac function. A short-term moderate CR in not only normalized body weight in SL mice but also ameliorate the metabolic programming and reverse the cardiac dysfunction induced by PNOF
Espíndola, Rosina. "Effet de l'éducation physique quotidienne au primaire sur la condition physique à l'âge adulte". Thèse, Université du Québec à Trois-Rivières, 1998. http://depot-e.uqtr.ca/3771/1/000651150.pdf.
Texto completo da fonteDejours, Roxane. "Classes préparatoires, grandes écoles et entrée dans l'âge adulte : entre renoncement pulsionnel et sexualité". Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCB062.
Texto completo da fonteFrom a longitudinal study, conducted among 51 students of preparatory classes, and based on annual clinical interviews and on the award of projective tests (Rorschach and TAT), this thesis aims to study the links constructed by young adults with work in preparatory class and French "Grandes Écoles" from two perspectives: subjective springs of engagement in the preparatory program on the one hand, the possible consequences of this course for their mental functioning on the other hand. If heterogeneity that emerges from the exploration of their mental functioning makes impossible the definition of a "personality type" specific presiding over this commitment, the elements from the longitudinal follow are rather more significant. They confront us in particular to the issue of the student's active submission to the institution's requirements and their progressive standardization. Enabled by a paradoxical alliance between sublimation and defensive strategies based on the stopping of thought and splitting, this process is becoming increasingly important as they adapt to work constraints of preparatory classes and French Grandes Ecoles. Those latter have the main aim to prepare students to assume a senior manager position in firms, and the results of this research tend more widely to bring out the close links between the new forms of work organization in the world productive work and psychic transformations made during the course [preparatory classe- French Grande École]. Recalling also the essential role played by sexuality or, more specifically, infantile sexuality both in the relation of the subject to the world that in the links between men, they underline the importance for the humanities, putting into perspective of psychic reality with the social field
Samson, Nathalie. "Interactions des déglutitions non-nutritives avec la respiration de la période néonatale jusqu'à l'âge adulte". Thèse, Université de Sherbrooke, 2009. http://savoirs.usherbrooke.ca/handle/11143/4278.
Texto completo da fonteFréchette, Valérie. "Soutien à la transition vers l'âge adulte et à l'autodétermination chez des jeunes en centre jeunesse". Thèse, Université de Sherbrooke, 2017. http://hdl.handle.net/11143/11297.
Texto completo da fonteHamelin, Christine. "Violences sexuelles dans l'enfance et santé à l'âge adulte chez les femmes Kanakes de Nouvelle-Calédonie". Paris 11, 2010. http://www.theses.fr/2010PA11T029.
Texto completo da fonteBoulmier, Sandrine. "L' ours, héros socialisateur des européens. De l'enfance à l'âge adulte, de la préhistoire à nos jours". Montpellier 3, 2007. http://www.theses.fr/2007MON30046.
Texto completo da fonteHow has the bear’s status—anthropomophized by humankind—evolved: from being deified to being reduced to a mistreated animal and finally becoming the symbol of tenderness, children’s socializer Teddy bear? Using an ethnohistoric and deductive method, we investigate into the first signs of bear worship in sub-christian european societies, in which the bear is conceived as being parented to humankind and possessing supernatural powers. Then, during Europe’s conversion to Christianity, the bear comes to be regarded as a diabolic animal is the Church’s most hated adversary. Domesticated and exhibited by bear leaders, the bear afterwards regains a certain prestige through its usefulness in hunting and it furthermore lends added value to aristocracy’s patronyms. The plantigrade allows men and women to access to sexuality and marriage during bears’days festivities. In the twentieth century, the bear becomes the Teddy bear, a therapeutic object and socializer hero with which the child identifies himself through stories. Nowadays, hunted for by collectors and designed by creators, the Teddy bear is conceived as a work of art. Therefore the bear is, for the European man, a medium through which to enter into relation with his world, open up to it, and even affirm his identity through it. Whereas for the animal, it remains a continent where its survival has become a major political and economical stake
Gosselin, Edith. "Soutien social perçu suite à une agression sexuelle à l'enfance : problèmes relationnels et conjugaux à l'âge adulte". Doctoral thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/33771.
Texto completo da fonteVictims of childhood sexual abuse (CSA) are at risk of developing multiple symptoms in various spheres of functioning that may continue into adulthood and adversely affect the development and stability of couple relationships (Briere & Runtz, 1993). The nature and extent of this diversity is associated with the quality of support received by the child (Charuvastra & Cloitre, 2008, Godbout & al., 2014). In this context, the purpose of this study is to examine the extent of social support received by adult survivors of CSA and how it is associated with various indicators of couple relationships quality (attachment as well as psychological, sexual and conjugal distress). A sample of 1309 participants currently in a couple relationship was recruited from within the community to answer online questionnaires about CSA, support received following the unveiling of this event, attachment, psychological distress, marital and sexual distress. Of the sample, 19.1% (n = 250) reported having experienced CSA. Of these CSA victims, 15.6% (n = 39) reported receiving support following the unveiling, 17.6% (n = 44) received negative support, while 66.8% (n = 167) never disclosed CSA. Path analyses indicated that, consistent with our assumptions, negative support is associated with greater attachment difficulties (abandonment anxiety and avoidance of intimacy) that are associated with greater psychological, couple and sexual distress. These results show the protective role of perceived support in the development of psycho-sexo-relational consequences following the CSA. These results will contribute to the development of best practices in managing the unveiling of CSA in preventive and therapeutic interventions with couples where one of the partners has experienced this type of abusive experience.
Gélinas-Beaulieu, Jessyca. "Maltraitance durant l'enfance et satisfaction conjugale à l'âge adulte : recension des écrits et études de cas descriptives". Thèse, Université du Québec à Trois-Rivières, 2011. http://depot-e.uqtr.ca/2279/1/030275912.pdf.
Texto completo da fonteGueye, Aliou. "Alimentation durant l'adolescence : facteurs de troubles comportementaux et neurobiologiques à l'âge adulte : modèle animal chez le rat". Thesis, Bordeaux 2, 2010. http://www.theses.fr/2010BOR21805/document.
Texto completo da fonteAdolescent diet often contains an excessive amount of palatable food with high caloric and sugar contents. Clinical and epidemiological data show that overconsumption of these large foods and sugar beverage consumption may have consequences in adolescence during which the brain is still maturing.Several studies have shown that sugar overconsumption during adolescence have long lasting effect of disease incidence such as obesity, diabetes … However, little is known in the long lasting effect of behavior disorder related to sugar overconsumption early in life. Therefore we set up an animal model to investigate the long lasting effect of sugar overconsumption during adolescence (PND 30 - 46) in neurobiological and behavioral alterations at adulthood. Our results reveal that chronic free access to sugar during adolescence decreases motivation and induce a vertical downshift of dose response curve for natural sweet and no sweet solution at adulthood with no behaviour consequences for pharmacological reward such as cocaine. These behavioral alterations are specific: 1) to the 5% sucrose concentration which is the more rewarding dose in our rats; 2) to a long access to 5% sucrose because only these alterations of behavior are observed after 12h et 24h/day access but not after 2h/day access; 3) to the sweet taste of the solution exposure during adolescence but not to its caloric effect since saccharine (a no caloric and sweet solution) induces these behavioral alterations; 4) to the adolescent period because we show no effect when adult rats have access to a sucrose solution; 5) is not dependent on the rearing conditions during adolescence since singly housed or group housed rats show the same behavioural disorder. We also show that these long lasting behavioral alterations to palatable foods are associated to anxiogenic-like behaviors and a depressive-like state evaluated in the Novelty suppressed feeding test and the forced swimming test respectively. Chronic imipramine treatment from the end of adolescence onwards (PND 47) prevents this behavioral disorder. Immunohistochemical studies show that sucrose exposure during adolescence decreases neurogenesis in the dentate gyrus of the hippocampus and imipramine treatment restores this deficit. These results suggest the importance of diet during adolescence in the development of neuropsychiatric disorders at adulthood. Given our high sweet environment, all these data suggest that considerable effort must be conducted to control early life initiation of sugar
Coutelle, Romain. "Les spécificités du self dans les troubles du spectre de l'autisme sans déficience intellectuelle à l'âge adulte". Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAJ065/document.
Texto completo da fonteSince first descriptions of Autism, disorders of self have been seen as key symptoms. The Self-Memory System put forward by Conway describes the reciprocal relationships between the self and autobiographical memory. This model was the theoretical background of our investigations of the specificities of the self in adults with Autism Spectrum Disorder without Intellectual Deficiency. We addressed three issues: structural aspects, concepts and subjective characteristics of the self. Our results showed an impairment of structural aspects of self while concepts and subjective characteristics were spared. Indeed, we found that the social function of autobiographical memory was altered and that social self-images belonging to self-concepts were related to qualitatively different memories. Our results challenge the episodic autobiographical memory deficit classically reported and encourage new researches to explore the impact of social relationships on the self and autobiographical memory
Jacquillet, Grégory. "Effets d'une intoxication au cadmium sur la fonction rénale du rat de la naissance à l'âge adulte". Nice, 2007. http://www.theses.fr/2007NICE4043.
Texto completo da fonteThe aim of this study was to go further in the understanding of the mechanisms of the renal cadmium toxicity. Cadmium is one of the heavy metals which represents a risk for public health and even if it is well known that kidney is a target for this metal, some points remain unclear considering the apparition of renal damages during cadmium chronic exposure. Using in vivo experiments and after a chronic cadmium contamination, we have shown that a renal failure occurred in adult rats as well as in offspring. It was characterised by a dramatic decrease of the glomerular filtration rate with an increase of the fractional excretions of the main ions a few days after the exposure was stopped. In situ, using immunofluorescent microscopy, we have shown that the functional renal failure was associated with morphological damages characterized by the disruption of the intercellular tight junctions. In adult rats, we have also demonstrated that the delayed effect due to the chronic cadmium contamination was related to the increase of the apoptotic cell death in the whole kidney. During this work, we have shown that every cadmium exposure represents a danger for the kidney. This metal can accumulate in the tissue inducing a long term nephrotoxicity that can induce a renal failure at each stage of aging even after the animals are kept out the contamination source
Thomas, Cécile. "Etude d'une série de 10 cas de maladie de Still de l'adulte chez des antillaises". Bordeaux 2, 1996. http://www.theses.fr/1996BOR2M108.
Texto completo da fonteTchokote, Emilie Clarisse. "Sujet confronté à une déficience motrice acquise à l'âge adulte au Cameroun : représentations du vécu et du devenir". Rouen, 2014. http://www.theses.fr/2014ROUEL007.
Texto completo da fonteThis work focuses on representation of living and become of subject with motor deficiency acquired at adulthood. To understand how the subject attributes meaning to his future state, it is necessary to focus on the supports he needs and uses to surpass the adversity in the process of resilience. This is a dynamic process influenced by a subtle and evolutionary equilibrium between protection and risk factors. (Anaut, 2005 ; Cyrulnik, 2002 ; Dyer et McGuinness, 1996 ; Manciaux, 2006). However, the overlap of the internal and external resources likely to predict the subject's resilient capacities can experience distortions depending on the quality of support given to the subject. Thus, we formulated the hypothesis that « the establishment of the process of resilience through the resources (internal and external) makes it possible to understand the process of representation of living and become of the subject with motor deficiency acquired at adulthood ». In this study we were interested on men who are lodged in CNRPH in Yaounde. The purposive sampling technique (Depelteau, 2000), was used to get fifteen subjects who took part in a semi-directive interview based on the clinical method of qualitative research. The results showed that the subjects mobilise their internal and external potentialities and use them to fight against the psychological disorder. But the « psychic scars » are observed because of the difference that exist in the quality of support brought by the microsystem, exosystem and the mesosystem. The meeting point with the motor deficiency peers considered as resilience tutors offers the possibility for the subjects to have area for affection, mutual aid, mutual solidarity, activities and words space. The cultural representations are used in an ambivalent manner (positive and negative) and which either favour and/or disfavour the search for internal equilibrium. These cultural representations orientate how the subject rebuilds identity feelings and influences positively and/or negatively the search for psychic equilibrium. Moreover, it arises that from the same factor supposed to protect the subject, the same variable can block and facilitate the use of the resilience process obliging the subject to manage the internal difference of the factor or between the factors. This management is a function of circumstances, the cognitive evaluation and the resources which he has during this period of his existence. It is necessary to put in place a therapeutic framework to reinforce the resources. But, these results deserve to be in-depth by varying the tools for data-collection through inferential techniques from a projective situation
Chaminaud, Stéphanie. "Développement de la compréhension du langage non littéral de 4 ans à l'âge adulte : aspects pragmatiques et métapragmatiques". Poitiers, 2008. http://www.theses.fr/2008POIT5003.
Texto completo da fonteThe purpose of this work is to study the comprehension and the metapragmatic knowledge of three forms of nonliteral language (indirect requests / hints, idioms and conversational implicatures) in same participants. The comprehension is evaluated with a paradigm which exhibits the characteristics of natural language-production situations and meets the methodological requirements of experimental method. The results show that the context drives the understanding at different ages according to the nonliteral language forms, that there is an acquisition order of nonliteral language forms and that metapragmatic knowledge also depends of language domain to be acquired. Moreover, we show that the comprehension of phonologic-syntactic language-impaired children is relatively preserved. In conclusion, nonliteral language should not be studied as a category acquired at a given age
Boxberger, Manon. "Le microbiote cutané : analyse exploratoire de sa composition et de sa variation avec l'âge chez la femme adulte". Thesis, Aix-Marseille, 2022. http://www.theses.fr/2022AIXM0026.
Texto completo da fonteAmong the methods described as allowing the cultivation of microorganisms considered as "difficult to cultivate", one of the first strategies is based on the supplementation, customization or modification of isolation and culture media, and another is based on the mimicry of growth conditions in the natural environment. The MB2L medium was developed and used in this study to isolate and select skin bacteria whose growth is masked by the main skin species (such as Staphylococcus). In this study, in addition to showing a preferential pattern of carriage of different bacterial species between the two age groups, we isolated 20 new bacterial species never described before. Carriage analysis by qPCR of these new bacterial species was performed on large panels. This analysis made it possible to determine whether these bacteria were commensal or transient. Of our 20 novel bacterial species, 7 were determined as commensals, so potentially of greater interest for further investigations of their roles or what they could produce, and their interaction with the skin, notably through the coculture with 3D skin models. These organisms are the starting point of future investigations that aim to discover their potential beneficial role for the skin and create expectations for their use as probiotic and postbiotic or the discovery of new bacterial-derivate bioactive compounds (for the use as postbiotic), they could also be the substrate for experimental determination of prebiotic compounds
Riba, Ambre. "Les conséquences d'un stress en période périnatale sur l'homéostasie intestinale et la réponse au microbiote à l'âge adulte". Thesis, Toulouse, INPT, 2015. http://www.theses.fr/2015INPT0010/document.
Texto completo da fontePerinatal period is characterized by an immature intestinal barrier particularly permeable to luminal antigens and as such highly vulnerable to environmental factors like toxins, infections or stressful events. The appropriate maturation of intestinal barrier leads to intestinal homeostasis and tolerance toward luminal contents. Early life stressful events are associated with the development and/or maintenance of functional gastrointestinal disorders like Irritable Bowel Syndrome (IBS) or organic one like Inflammatory Bowel Diseases (IBD). These pathologies are highly different in term of etiology and clinical severity however they share common features like alteration in intestinal barrier associated with an abnormal immune response toward luminal contents especially commensal microbiota. Our aim was to evaluate the consequences of maternal separation (MS) on intestinal homeostasis, host-microbiota relationship and the humoral and cellular response at adulthood. Due to sexual dimorphism in this model, the results are presented separately for male and female. In young adult male mice, MS decreases intestinal barrier functions associated with an alteration of systemic humoral and cellular response toward commensal microbiota. Moreover, a defect of antigen presenting cells in spleen leads to systemic low grade inflammation despite a pro-inflammatory profile of T cell. In young adult female mice, MS alters the functionality of Paneth cells associated with an intestinal bacterial overgrowth, leading to visceral sensitivity and systemic humoral response toward commensal microbiota. We highlighted that MS has long lasting adverse effects on intestinal homeostasis and systemic immune response toward commensal microbiota in young adult. MS impairs intestinal homeostasis in healthy individuals and might contribute to trigger intestinal pathologies in susceptible persons
Noël, Catherine. "Étude longitudinale des liens entre les types d'attachement à l'adolescence, la motivation autodéterminée et l'ajustement psychosocial à l'âge adulte". Thesis, Université Laval, 2008. http://www.theses.ulaval.ca/2008/25080/25080.pdf.
Texto completo da fonteChevrier, Basilie. "Approche longitudinale de l'ajustement psychosocial des étudiants primo-entrants en contexte universitaire : une question de transition vers l'âge adulte". Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0233.
Texto completo da fonteStarting university is a period of major transition with many changes in roles, statuses, and environments. This transitional period corresponds to the beginning of the becoming an adult. The developmental challenge of this time involves autonomy and independence issues. Autonomy and independence are acquired progressively and are expressed through young adults’ representations of family functioning and their own functioning. Thus, the family environment, attachment representations, home-leaving experience, and self-determination processes are expressions of becoming adult that are particularly questioned during this major transition. With a holistic-interactionist point of view, the current research aims to investigate young adults’ psychosocial development when they enter at the university considering specificities of the developmental period.Our sample consisted of freshman young adults. Using a longitudinal approach, this research had three waves and to two separate cohorts. The first wave was during the back-to- school period, in September/October (N = 1,142); the second wave in the middle of the freshman year, in February/March (N = 248); and the third wave at the end of the year, in June/July (N = 101). In each wave, participants completed the questionnaire assessing family environment (i.e., parents-child relationship and family relationships), attachment representations, home-leaving, self-determination process (i.e., academic motivation and basic psychological needs), and psychosocial adjustment (i.e., psychological well-being, self- worth, depression, and academic results). Data were analyzed using both person-oriented and variable-oriented approaches and considered the different kinds of variability.Our results highlight the heterogeneity and multiplicity of family environment, attachment, and self-determination profiles, home leaving classes, and developmental patterns in the beginning of the freshman year. Family environment, attachment, and self- determination profiles presented a singular evolution during freshman year. Concerning psychosocial adjustment, our results showed that personal characteristics (i.e., attachment and self-determination processes) have an effect on adjustment across the freshman year unlike environmental contexts (i.e., family environment and home leaving). Psychosocial adjustment evolution during the year appeared to be positive and stable for positive profiles of family environment, attachment, and self-determination whereas it was unstable for negative profiles. Finally, our results replace basic psychological needs as important levers allowing a better adaptation during transitional periods. These different observations give a complementary perspective to literature and provide an opportunity to discuss possible applications in the support of emerging adults in the university context
Viscogliosi, Caroline. "Relation entre les symptômes du trouble d'anxiété généralisée à l'âge adulte et les comportements parentaux perçus durant l'enfance et l'adolescence". Thèse, Université de Sherbrooke, 2010. http://savoirs.usherbrooke.ca/handle/11143/2813.
Texto completo da fonteFidolini, Vulca. "Les constructions de l'hétéronormativité : sexualité, masculinités et transition vers l'âge adulte chez de jeunes marocains en France et en Italie". Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAG025/document.
Texto completo da fonteThis thesis investigates representations of sexuality and constructions of masculinity among young Moroccan Muslim men (aged between 20 and 30) who migrated to France (Alsace) and Italy (Tuscany). Sexual accounts and gender identification processes are the main fields to study heteronormativity and to show how its hegemonic power is interwoven with other social relations which define the transition to adulthood of these young men. By exploring the outcomes of a qualitative research – based on ethnographic observation and interviews – this study demonstrates that heteronormativity, far from being a monolithic power, is a plural norm which produces not only social constructions of sexuality and masculinity among young Moroccans, but also shapes intra- and intergenerational relationships, relations among minority groups, and between migrants and the majority population
Langlois, Émilie. "Les liens entre l'attachement aux parents à la fin de l'adolescence et les relations amoureuses et conjugales à l'âge adulte". Doctoral thesis, Université Laval, 2021. http://hdl.handle.net/20.500.11794/68546.
Texto completo da fonteThree meta-analyses were conducted to synthesize results of previous research on the association between adult attachment with parents and the quality of romantic relationships in adulthood. These meta-analyzes address the link between attachment security and three components of romantic relationships, namely the quality of interactions, attachment to the partner and dyadic satisfaction. Results indicate a moderate association between adult attachment and each of these components of romantic relationships. A longitudinal study was subsequently conducted to address specific questions raised by these meta-analyses. The link between attachment and romantic relationships in adulthood was examined in a longitudinal study, starting in adolescence and continuing until participants were 41-years-old (mean). Seventy-five individuals participated at three different time points. The first participation took place in 1992 or 1996 (time 1), the second in 2007 (time 2), and the third in 2019 (time 3). Measures on the quality of their relationships, and the stability of their relationships were obtained at times 2 and 3, where as attachment data (Adult Attachment Interview; AAI) was collected at time 1, when participants were late adolescents or early adults. A double mediation model shows that adolescents who are more preoccupied with attachment are less intimate and less involved in their romantic relationships at the age of 28; that a low level of perceived intimacy and engagement at the age of 28 is associated with low level of stabilityin romantic relationships in the early 40s; that a shorter relationship in the early 40s is associated with a weaker commitment to the partner. The results of these studies suggest that attachment organization in late adolescents and young adults may have a bearing on the mechanisms involved in the dynamics of romantic relationships during adulthood.
Rissoan, Odile. "Trajectoires amicales et construction des positions lors du passage à l'âge adulte : enquête auprès d'un amphithéâtre d'étudiants en première année". Lyon 2, 2002. http://theses.univ-lyon2.fr/documents/lyon2/2002/rissoan_o.
Texto completo da fonteDreyfuss, Monique. "Mémoire et mémorisation dans les autismes de l'enfance à l'âge adulte : une étude à partir de la notion de protodiakrisis". Paris 8, 2005. http://www.theses.fr/2005PA082616.
Texto completo da fonteCrossard, Elodie. "Ontogenèse des neurones à kisspeptine chez le rat : neurogénèse et cartographie spatio-temporelle de kisspeptine de l'embryogénèse à l'âge adulte". Thesis, Tours, 2011. http://www.theses.fr/2011TOUR4026/document.
Texto completo da fonteKisspeptin (kp) is a neuropeptide, derived from the kiss-1 gene, which plays a key role in the central control of reproduction by regulating GnRH secretion in adult but also during development. Cells which express kiss-1 are localized in two distincts hypothalamic regions: the rostral peri-ventricular third ventricule area (RP3V) and the arcuate nucleus (ARC). Kiss-1 expression is highly regulated by sex steroids: positively in the RP3V and negatively in the ARC. RP3V kp neurons have been implicated in the pre-ovulatory GnRH surge whereas ARC kp neurons may predominantly act on GnRH secretion pulsatility. The aim of this PhD work was to determine the neurogenesis period of kp neurons and changes of kiss-1 and kp expression in both regions during different stages of development in rats. Our results highlight key periods of kp neurons ontogenesis and show that: 1) ARC kp neurons are born during an extended embryonic neurogenesis period starting at embryonic day (E) 12,5; 2) a sex independent down-regulation of kp occurs during peri-natal period; 3) sex difference in the expression level and neuroanatomique distribution of kp establishes during neo-natal period; 4) kp was regulated during peri-pubertal period in sex and region dependant manner; 5) kp-ir fibers are detected throughout the septo-hypothalamic continuum suggesting that kp could be implicated in other functions than reproductive function
Grynkorn, Meas Taly. "Programmation foetale de l'insulinorésistance et du syndrôme métabolique : contribution du développement de l'adiposité à l'âge adulte dans la cohorte haguenau". Paris 7, 2010. http://www.theses.fr/2010PA077026.
Texto completo da fonteMetabolic consequences of being born small for gestational age (SGA) begin to be well known. The biological mechanisms underlying this association are still unknown. To explain this association, the particular dynamic changes in adiposity that occur during catch-up growth have been evoked. Moreover the interactions with modifications of body composition later in life seem to play an important role. Our group has been working on this field since several years. We used a population-based registry, located in the city area of Haguenau. Subjects from this cohort were selected on birth criteria: 734 subjects born full-term SGA, (BW< 10th percentile) were compared to 886 subjects born Appropriate for Gestational Age (AGA: 25th
Tordjman, Michel. "Ostéomalacie hypophosphorémique vitamino D resistante découverte à l'âge adulte liée au chromosome X : à propos de l'observation familiale de deux cas". Bordeaux 2, 1993. http://www.theses.fr/1993BOR2M082.
Texto completo da fonteLapointe, Frédérique, e Frédérique Lapointe. "Tracer son chemin : la transition à la vie adulte des femmes ayant expérimenté l'itinérance". Master's thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/37561.
Texto completo da fonteCertains groupes de la population sans domicile fixe sont identifiés comme particulièrement vulnérables. Les femmes et les jeunes adultes en font partie. En plus d’être spécifiquement touchées par certaines formes d’adversité au courant de leur vécu de rue, ces franges minorisées des populations en situation d’itinérance sont rarement représentées dans les politiques sociales et les dénombrements entourant ce phénomène. Le but de cette recherche est de faire entendre les voix de femmes ayant expérimenté l’itinérance sur la façon dont elles vivent ou ont vécu leur transition à la vie adulte. Prenant appui sur la perspective intersectionnelle socioconstructionniste, cette étude a cherché à éclairer leur expérience et leur compréhension de leur situation, tout en mettant en lumière les mécanismes d’oppression et les stratégies de résistance présents dans leur parcours. Misant sur une approche narrative, cette recherche qualitative a été réalisée par le biais d’entretiens individuels auprès de cinq jeunes femmes afin de recueillir le récit personnel de leur passage à la vie adulte. Ainsi, le parcours singulier de chacune de ces femmes de même que les similitudes et les différences entre leurs situations respectives ont été analysées pour mieux comprendre leurs expériences semblables et variables de l’itinérance au cours du passage à la vie adulte. Les résultats décrivent des parcours faits de départs, de nouvelles rencontres et de prises de décisions menant vers diverses situations de revenus et d’hébergement. Au-delà des interprétations qu’elles font de leur vécu respectif, les participantes éclairent les mécanismes d’oppression auxquels elles sont confrontées, incluant diverses formes de mise à l’écart et de violence, ainsi que les stratégies qu’elles emploient pour améliorer leur sort.
Some groups of the homeless population are identified as particularly vulnerable. Women and young adults are part of them. In addition to being specifically affected by certain forms of adversity when they are on the streets, these minority fringes of homelessness are rarely represented in social policies and are not included in the numbers regarding this phenomenon. The purpose of this research is to put forward the experience of transition to adulthood of women who experience, or have experienced, homelessness. Drawing on the intersectional socioconstructionist perspective, this study sought to shed light on their path and understanding of their situation, while highlighting the mechanisms of oppression and the strategies of resistance. Using a narrative approach, this qualitative research was conducted through individual interviews with five young women. Thus, each of these women's unique pathways as well as the similarities and differences between their respective situations were analyzed to better understand their similar and variable experiences of homelessness during the pathway of adult life. The results describe journeys made of departures, new encounters and decision-making leading to various income and housing situations. Beyond the interpretations they make of their experiences, the participants shed light on the oppression mechanisms they face, including various forms of exclusion and violence, as well as the strategies they employ to improve their lives.
Some groups of the homeless population are identified as particularly vulnerable. Women and young adults are part of them. In addition to being specifically affected by certain forms of adversity when they are on the streets, these minority fringes of homelessness are rarely represented in social policies and are not included in the numbers regarding this phenomenon. The purpose of this research is to put forward the experience of transition to adulthood of women who experience, or have experienced, homelessness. Drawing on the intersectional socioconstructionist perspective, this study sought to shed light on their path and understanding of their situation, while highlighting the mechanisms of oppression and the strategies of resistance. Using a narrative approach, this qualitative research was conducted through individual interviews with five young women. Thus, each of these women's unique pathways as well as the similarities and differences between their respective situations were analyzed to better understand their similar and variable experiences of homelessness during the pathway of adult life. The results describe journeys made of departures, new encounters and decision-making leading to various income and housing situations. Beyond the interpretations they make of their experiences, the participants shed light on the oppression mechanisms they face, including various forms of exclusion and violence, as well as the strategies they employ to improve their lives.
Duong, Van Huyen Jean-Paul. "Exposition in utero au diabète maternel chez le rat : altération de la néphrogénèse et programmation fœtale d'une hypertension artérielle à l'âge adulte". Paris 6, 2007. http://www.theses.fr/2007PA066071.
Texto completo da fonteCantin, Jessica. "L'expérience de la séparation parentale durant l'enfance et ses incidences à l'âge adulte : vécus et effets perçus par des enfants aujourd'hui adultes". Master's thesis, Université Laval, 2020. http://hdl.handle.net/20.500.11794/40193.
Texto completo da fonteRaji, Bahija. "Etude de l'expression des protéines Musashi1 et Partner of Inscuteable Pins dans l'oeil de souris au cours de développement et à l'âge adulte". Paris 7, 2007. http://www.theses.fr/2007PA077145.
Texto completo da fonteIn this work, we studied the expression and the role of the Musashi1 and partner of inscuteable (Pins) proteins in the development of the eye. We showed an expression of Msi1 in various potential sites of ocular stem cells during the development and at adulthood. These zones include the retina, ciliary body, iris, pigmentary epithelium, lens, cornea and the limbus. Msi1 is also present in the adult neurons. This distribution in various ocular compartiments and at various stages of the development suggests that Msi1 could play an important role at multiple stages of the eye development. Msi1 could be also implied in physiology and function of the adult neurons. We also showed that the Pins protein is expressed in the retinal cells very early during the embryonic development where it could play an important role in stem/progenitors cells division. The expression of Pins protein in the photoreceptors, implied in Visual transduction, suggests that this protein could play an important role in this process. In addition, the predominent expression of Pins protein in the lens epithelial cells and fibers lens at the adulthood pointed out the probable important roles of this protein in the growth and the maintenance of the physiological properties of the lens. Keywords: Musashi1, Pins, asymmetric cell division, stem cells, adult neurons
Baracat, Bruno. "Changements liés à l'âge dans les processus de prise de décision. Application de la théorie de la détection du signal chez l'homme adulte". Toulouse 3, 1992. http://www.theses.fr/1992TOU30255.
Texto completo da fonteLefebvre, Myriam. "Contribution des indices du trouble déficitaire de l'attention-hyperactivité dans la présence de troubles mentaux à l'âge adulte dont, le trouble de personnalité antisociale". Mémoire, Université de Sherbrooke, 2013. http://hdl.handle.net/11143/6418.
Texto completo da fonteBrus, Aude. "Anthropométrie d'un milieu rural français(1976-2006) : étude auxologique et relations entre biométrie à l'âge adulte, modalités de croissance et pratiques alimentaires et corporelles". Aix-Marseille 2, 2008. http://www.theses.fr/2008AIX20705.
Texto completo da fonteA French rural population (Châteauponsac, Limousin, France) was measured from childhood to adulthood. Such data corpus is rare and allows several analytic and interdisciplinary studies. We first describe the average growth of subjects aged from 6 to 16 years-old. Percentiles are determined using LMS method. Curves are compared with French growth standards (Parisian sample). Comparison of height curves shows few differences between both populations. However, children from Châteauponsac mature earlier. This precocity may be related to secular trend. Nevertheless, the variability of individual growth patterns is not well described by percentiles. Thus, we analyse longitudinally the height data from the Châteauponsac and Paris samples. Comparison of individual patterns of two French populations has never been presented. It shows that children from Châteauponsac present a later maximal pre pubertal deceleration compare to the Parisians. This delay may be caused by environmental differences (rural versus urban). Divergence of results when average growth curves are compared with individual growth curves underlines difficulties to compare several growth standards built with different statistical method. Growth standards used by French clinicians are out of date and methods used are obsolete. These growth norms need to be updated. Furthermore, curves describing body mass index evolution during growth show a worrying increase of overweight among children during the last decades. Since growth data and adult nutritional status are known, we finally look for relationships between adult overweight prevalence and growth patterns. Longitudinal analysis allows the determination of ages of pre pubertal deceleration and pubertal growth spurt which permit to differentiate pre pubertal, pubertal and post pubertal periods for each subject. Results show that body mass index is correlated to corpulence during childhood and adolescence and to growth patterns. Nevertheless, our study, associated with the analysis of social and behavioural information, reveals that nutritional status is not independent of nutritional and body practises and social pressure of health and thinness broadcasted by medias. In order to manage overweight increase, it is essential to understand the etiology of weight excess, although its origins are complex and multifactorial (biological, environmental, social, psychological causes). Moreover, it is necessary to beware of behavioural normative discourses which could product undesirable effects
Le, gall Anne. "Influence de la graviception vestibulaire sur le développement et les fonctions cognitivo-motrices à l'âge adulte : étude longitudinale chez un modèle murin vestibulo-déficient". Thesis, Normandie, 2017. http://www.theses.fr/2017NORMC421.
Texto completo da fonteEarth’s gravity is a fundamental mechanical constraint for living organisms against which we have adapted our strategies of posture and locomotion as well as all metabolic and cardiovascular regulations. Beyond the mechanical stimulus, the vestibular organ is the first sensory system to emerge in protochordates about 500 million years ago, as early as the visual system, encoding the gravity strength into the brain. The vestibular system has since then been devoted to balance and gaze stabilization supported by postural and ocular reflexes, recently fortified with a key role in spatial and social cognition in adults. Its encoding abilities of head movements, body accelerations and Earth's gravity make this system a major player in the perception of verticality, navigation, orientation and spatial memorization. We have hypothesized that vestibular sensory perception of gravity might play a crucial role not only in adults, but also during the first stages of development in both sensorimotor and cognitive functions. For the first time, we have investigated an original mouse model (Head-Tilt mice, B6Ei.GL-Nox3Het/J) with selective congenital absence of vestibular gravisensors. Our data highlights that mouse pups suffered from a delay in the acquisition of sensorimotor reflexes, spatial olfactive guidance, path integration and ultrasonic communication while maternal care remained normal. In addition, a delay in locomotor development and the appearance of were observed during the late stage of development. We demonstrate that development on Earth has a critical period dependent on the vestibular sensory perception of gravity, at least between postnatal days 6 to 10 in rodents. We have shown that otolithic information plays a key role in the adult motor functions, spatial and non-spatial memory processes, reference frames choice but also in emotional regulation. These disorders have been correlated with early developmental delay. We are currently working on the effects of early sensory stimulation on development and adult functions in our Het mouse model as well as on the structural and functional characterization at the cerebral level of observed developmental and behavioral impairments. Observations in Het mice corroborate with symptoms reported in vestibulo-deficient children, supporting the need for better screening of vestibular diseases during childhood. Remarkably, the symptoms of our vestibulo-congenital deficient mice investigated here matched with the profile of validated mouse models of autism and re-update the significance of vestibular graviception in the physiopathology and therapy of autism spectrum disorders during its development
Chiarelli, Clémentine. "Des enjeux psychiques de l'engagement et du militantisme dans un parti politique à l'adolescence et au début de l'âge adulte : approche psychodynamique et projective". Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCB220.
Texto completo da fonteIf political parties are often referred as "traditional" and therefore "outdated" institutions, they continue anyhow to participate in "living together" and are still the main institutions that compete in local and national elections. Their main target is the conquest and the exercise of power at all steps. Despite the mistrust in these institutions, especially among adolescents and young adults, some of them are still engaging and militating, sometimes intensely, in the party-political youth organizations of political parties. Our thesis aims to highlight psychic issues of the adolescents and young adults' involvement in political parties. In an attempt to take those stakes into account, two questions guided our research. Firstly, In France today, what are the psychic functioning modalities of adolescents and young adults who militate in a political party, what are their eventual common psychic characteristics? Secondly, regarding the psychic processes mobilized in adolescence and early adulthood for these subjects, what would be the function and effect of the engagement and militancy in a political party? Between January 2015 and June 2016, thirty-six young activists, aged between 18 and 26, agreed to participate in the research. Political organizations in which these young activists committed themselves represent the entire political spectrum, from the extreme left to the far right. In order to address the questions raised a methodology including both individual semi-structured interviews and projective tests (Rorschach and TAT) has been set up. While the projective tests enable us to apprehend shrewdly the characteristics of the young militants individual psychic functioning, individual interviews provide valuable insights of their personal story and their militant journey. First of all, the results show the heterogeneity of the psychic resources and fragilities according each militant, which leads us to believe that there is no specific psychological profile for this population. However, we find common characteristics among National Front activist, which conduct us to make the hypothesis of a resonance between these psychic characteristics and this political party's advocated ideas and ideals. A question remains: why don't we find the same phenomenon amongst the other political parties and related activists; in that regard, a reflection path is proposed in this thesis. Moreover, the findings of this study, allow us to state that a political party can provide a more or less effective support for the management of the psychic conflicts peculiar to the adolescence and to the adulthood. Does the effectiveness of this support exclusively depend the resources and psychic weaknesses preexisting in young activists? It would seem not. This research shows that the framework of political organization is far from contingent to the activists' individual psychic functioning. Thus, it is important to consider both the psychic functioning has been built through the individual history of the militants, and the organizational constraints they confront, in order to evaluate, from a psychic point of view, the extent to which this commitment has a mutative effect
Mellerio, Hélène. "Devenir à l'âge adulte des enfants porteurs de pathologie chronique : exemples de la transplantation rénale pour insuffisance rénale terminale et du diabète de type 1". Sorbonne Paris Cité, 2015. https://theses.hal.science/tel-01366720.
Texto completo da fonteAlthough chronic diseases affect social life at any age, the long-term social outcome of children with chronic disease is uncertain. Our objective was to describe social life, quality of life (QOL ; SF36), sexuality and experience of transition from pediatric to adult care of pediatric renal transplant recipients (Transdevenir study) or children with type 1 diabetes (T1D)(Diabdevenir study) at adult age. Data of these two GEDEPAC French multicenter studies were collected by self-administered questionnaire (199 items) and compared with the general population (GP) by Standardized Incidence Ratios (SIR) matched for age-sex-period. In Transdevenir (n=374 ; median age (years) at survey = 27. 1 ; at 1st transplant=12. 3 ; functioning graft = 81%), difficulties of social integration were identified : less frequent marital life (SIR=0. 60), lower educational level, higher unemployment (SIR=1. 77) and fixed-term contracts (SIR=1. 79) rates. The social participation was negatively correlated to : disease severity (early diagnosis, hereditary disease, comorbidity), lower personal or parental educational level, and young age. The global QOL was reduced. In Diabdevenir (n=388 ; mean age=28. 5±3. 1yrs ; mean DT1 duration=17±2. 7yrs), social participation was satisfying (educational level, unemployment and familial life similar to GP). However, the daily alcohol consumption was more frequent (SIR=men : 3. 1;women :6. 1), as well as dissatisfaction with sexuality, and mental QOL was significantly decreased. To develop research on long-term well-being of children with other chronic diseases, the GEDEPAC-2 questionnaire was constructed (validation in progress)
Richard, Marie-Claude. "Trajectoires de passage à la vie adulte de personnes ayant fait l'objet d'une mesure de placement en milieu de vie substitut jusqu'à la majorité". Thesis, Université Laval, 2012. http://www.theses.ulaval.ca/2012/29115/29115.pdf.
Texto completo da fonteGallant, Martine. "Le type de garde parentale et la structure des visites suite au divorce et leurs effets sur les confiances générale et relationnelle des enfants à l'âge adulte". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ37846.pdf.
Texto completo da fonteLabonté-Fournier, Sébastien. "DIMORPHISME SEXUEL DES RÉPONSES PHYSIOLOGIQUES À l'HYPOXIE CHEZ LE RAT : ÉTUDE DU RÔLE DES HORMONES SEXUELLES DANS LA PROGRAMMATION NÉONATALE ET DANS LA RÉGULATION À L'ÂGE ADULTE". Thesis, Université Laval, 2013. http://www.theses.ulaval.ca/2013/29553/29553.pdf.
Texto completo da fonteDecoppet, Nathalie. "Les effets d'âge d'acquisition de la forme orthographique des mots : illusion ou réalité ? : une approche développementale de la construction des mémoires orthographiques entre l'enfance et l'âge adulte". Lyon 2, 2005. http://theses.univ-lyon2.fr/documents/lyon2/2005/decoppet_n.
Texto completo da fonteOver the past two decades, an increasing number of studies have empirically established that the age at which words were learnt in childhood has an independent effect on the efficiency with which these words can be recognised and produced in adults. However, Age of Acquistion (AoA) effects in word reading have recently undergone some challenging criticism by Zevin and Seidenberg (2002). Based on their connectionist modelling, these authors have indeed argued that the AoA effects should only emerge in cases where the learning process requires memorising arbitrary patterns, which does not apply to the orthography-to-phonology mapping utilised in alphabetic systems. In an attempt to circumscribe this quite radical position, the work presented here aims to provide both an empirical description and a theoretical account of the AoA phenomenon and its origins, using new measurements specifically focused on the age at which the orthographic forms of words are learnt. Taken together, the data collected among children or adults and for different languages, plead in favour of the rehabilitation of the AoA effect in visual word recognition, but confirms simultaneously that residual influence of AoA in skilled performance indeed depends on whether what is learned about early patterns carries over in later patterns. Results are discussed in reference to the classical view of reading development supported by parallel and distributed processing networks, and some perspectives for the instruction of reading are proposed