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Radzevičienė, Lina. "Sergančiųjų cukriniu diabetu mokymo organizavimo ir kokybės vertinimas poliklinikoje". Master's thesis, Lithuanian Academic Libraries Network (LABT), 2006. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20060612_144532-92108.
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Aim of the study. To assess the organization possibilities and evaluate the quality of diabetes education in outpatient clinic.
Methods. The anonymous questionnaire survey was performed among adult diabetic patients in Kaunas Dainava outpatient clinic in october-December, 2005. 500 questionnaire were given to the patients, the responce rate was 354 patients (70.8 %). The data was analysed by application of statistical package SPSS 12.0 for Windows. The associations between the variables were measured using the Chi-squared (χ²) test.
Results. The positive evaluation of diabetes education in Kaunas Dainava outpatient clinic was given by 73.7 % of patients. 98.3 % believed that diabetes education is necessary. 77.9 % knew about diabetes, 80.8 % - were aware of fasting glycaemia criteria, 95.3 % - glycaemia in untreated patients. 82.2 % understood the importance of diet and it‘s ingredients (90.6 %). Less than a half (40.4 %) were aware of glycated hemoglobin and importance of postprandial glycaemia. Only 33.2 % of those taught in „Diabetes school“ had adequate diabetes control. The target glycated hemoglobin was reached in 42.1 % of thosewho attended the inpatient „Diabetes school“ and only in 22.5 % of those who didn‘t. Diabetes complications have been diagnosed in 43.7 % of those whose glycated hemoglobin ≤ 7 % and in 76.2 % of those whose glycated hemoglobin > 7 %.
Conclusions. Diabetes education in Kaunas Dainava outpatient clinic is not sistematic organized, the time of... [to full text]
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Pouladi, Fatemah Ali RN. "Diabets Knowledge, Self-Effecacy, Social Support, and Diabetes Self-management Affecting Type II Diabetes Outcomes In Qataris". Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case151512792425253.
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Beales, Philip Edward. "Diabetes prevention in the non-obese diabetic mouse". Thesis, University of East London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265059.
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Dow, Courtney. "Dietary Factors, Type 2 Diabetes and Diabetic Retinopathy". Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS380/document.
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Contexte : Le diabète de type 2 (DT2) constitue une pathologie majeure, au lourd fardeau, associ ée à de nombreuses complications, comme la rétinopathie diabétique (RD). Des facteurs modifiables, comme l’alimentation, ont déjà été identifiés pour le DT2 et la RD mais certains aspects de leurs rôles restent à préciser. Objectifs : Les objectifs de cette thèse étaient d’examiner le rôle de l’alimentation, en particulier la consommation d’acides gras (AGs), et des autres facteurs modifiables liés au mode de vie sur le risque de DT2 et de synthétiser, interpréter et analyser la relation entre l’alimentation et la RD. Résultats : Les résultats suggèrent que le rôle des AGs sur le risque de DT2 et de la RD pourrait être différent selon leur type, et même varier au sein d’un groupe comme les AG polyinsaturés (AGPI). Les résultats suggèrent aussi qu’une forte adhésion aux recommandations alimentaires n’est pas associée avec le développement d’un DT2, mais en revanche une forte adhérence aux autres recommandations de santé (concernant le tour de taille, l’activité physique et le statut tabagique) est fortement associée avec un moindre risque de DT2. On a montré qu’avoir un mode de vie sain aurait pu empêcher la survenue de plus de la moitié des cas de DT2. Conclusions : Cette thèse a permis de préciser l’importance et la complexité du rôle de l’alimentation dans le développement du DT2 et de la RD. Elle montre aussi l’impact des comportements sains dans la pathologie de DT2 et confirme que le DT2 est en grande partie, une maladie évitable. Les efforts devraient se focaliser sur la modification des comportements de santé à la fois dans la population générale et atteinte de DT2 et notamment encourager une alimentation modérée et variéeBackground : Type 2 diabetes (T2D) presents a significant health burden that is associated with many complications, such as diabetic retinopathy (DR), that further burden people with diabetes. Modifiable risk factors, such as the diet, have been identified for both T2D and DR; yet certain aspects of the role of the diet remain unclear. Objectives : The main objectives of this thesis were therefore to examine the role and impact of the diet, and in particular, the consumption of fatty acids (FAs), and other modifiable behaviours on the risk of T2D and to summarize, interpret and analyze the relationship between the diet and DR using data from both the E3N and AusDiab cohort studies. Results : The results suggest that the role of FAs on the risk of T2D and DR may differ between and within subgroups, and by individual polyunsaturated fatty acids (PUFAs). The findings also suggest that strongly adhering to national dietary guidelines is not associated with the development of T2D, but strongly adhering to other recommendations for healthy behaviours (for waist circumference, physical activity and smoking) is strongly inversely associated with T2D. Modifiable behaviour could have prevented more than half of the cases of T2D. Conclusions : This work underlines the importance and the complexity of the role of the diet in the development of T2D and DR. It also illustrates the impact of healthy behaviour in the etiology of T2D and confirms that T2D is largely preventable. Efforts should focus on the modification of multiple healthy behaviours in populations, and promote diets that are moderate and widely varied
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Rosenfeld, Ellie. "The care of the feet of people with type 2 diabetes in South Australian general practice /". Title page, table of contents and summary only, 1998. http://web4.library.adelaide.edu.au/theses/09MPM/09mpmr813.pdf.
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Naemiratch, Bhensri. "Who is in control : the diabetic or diabetes? lived experience of adults living with diabetes in Bangkok /". [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18681.pdf.
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Orr, Neil John. "Patterns of care for diabetes: risk factors for vision-threatening retinopathy". Thesis, The University of Sydney, 2005. http://hdl.handle.net/2123/1421.
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OBJECTIVES: In Australia, diabetes causes significant morbidity and mortality. Whilst the need to prevent diabetes and its complications has been widely recognised, the capacity of health care systems - which organise diabetes care - to facilitate prevention has not been fully established. METHODS: A series of seven population-based case-control studies were used to examine the effectiveness of the Australian health care system and its capacity to manage diabetes. Six of the studies compared the patterns of care of patients who had developed advanced diabetes complications in 2000 (cases), to similar patients who remained free of the condition (controls) across Australia and for various risk groups. A secondary study investigated the role of treating GPs in the development of the outcome. RESULTS: A strong relationship between the patterns of care and the development of advanced diabetes complications was found and is described in Chapter 4. In Chapter 5, this same relationship was investigated for each Australian state and territory, and similar findings were made. The study in Chapter 6 investigated whether late diagnosis or the patterns of care was the stronger risk factor for advanced diabetes complications, finding that the greatest risk was associated with the latter. In Chapter 7 the influence of medical care during the pre-diagnosis period was explored, and a strong relationship between care obtained in this period and the development of advanced complications was found. In Chapter 8, which investigated the role of socio-economic status in the development of advanced complications, found that the risk of advanced diabetes complications was higher in low socio-economic groups. Chapter 9 investigated geographic isolation and the development of advanced diabetes complications and found that the risk of advanced complications was higher in geographically isolated populations. Finally, Chapter 10, which utilised a provider database, found that some GP characteristics were associated with the development of advanced diabetes complications in patients. CONCLUSION: A number of major risk factors for the development of advanced complications in Australia was found. These related to poorer diabetes management, later diagnosis, low socioeconomic status and geographic isolation. Strategies must be devised to promote effective diabetes management and the early diagnosis of diabetes across the Australian population.
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Orr, Neil John. "Patterns of care for diabetes: risk factors for vision-threatening retinopathy". University of Sydney, 2005. http://hdl.handle.net/2123/1421.
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Master of Public HealthOBJECTIVES: In Australia, diabetes causes significant morbidity and mortality. Whilst the need to prevent diabetes and its complications has been widely recognised, the capacity of health care systems - which organise diabetes care - to facilitate prevention has not been fully established. METHODS: A series of seven population-based case-control studies were used to examine the effectiveness of the Australian health care system and its capacity to manage diabetes. Six of the studies compared the patterns of care of patients who had developed advanced diabetes complications in 2000 (cases), to similar patients who remained free of the condition (controls) across Australia and for various risk groups. A secondary study investigated the role of treating GPs in the development of the outcome. RESULTS: A strong relationship between the patterns of care and the development of advanced diabetes complications was found and is described in Chapter 4. In Chapter 5, this same relationship was investigated for each Australian state and territory, and similar findings were made. The study in Chapter 6 investigated whether late diagnosis or the patterns of care was the stronger risk factor for advanced diabetes complications, finding that the greatest risk was associated with the latter. In Chapter 7 the influence of medical care during the pre-diagnosis period was explored, and a strong relationship between care obtained in this period and the development of advanced complications was found. In Chapter 8, which investigated the role of socio-economic status in the development of advanced complications, found that the risk of advanced diabetes complications was higher in low socio-economic groups. Chapter 9 investigated geographic isolation and the development of advanced diabetes complications and found that the risk of advanced complications was higher in geographically isolated populations. Finally, Chapter 10, which utilised a provider database, found that some GP characteristics were associated with the development of advanced diabetes complications in patients. CONCLUSION: A number of major risk factors for the development of advanced complications in Australia was found. These related to poorer diabetes management, later diagnosis, low socioeconomic status and geographic isolation. Strategies must be devised to promote effective diabetes management and the early diagnosis of diabetes across the Australian population.
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Myers, Valerie Harwell Herbert James D. "Mood and anxiety symptomatology in adults with insulin-dependent Diabetes Mellitus using intensive management regimens /". Philadelphia, Pa. : Drexel University, 2003. http://dspace.library.drexel.edu/handle/1860/233.
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McKnight, A. J. "Genetic predisposition to diabetic nephropathy in type 1 diabetes". Thesis, Queen's University Belfast, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396899.
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Fagerudd, Johan. "Familial factors and diabetic nephropathy in type 1 diabetes". Helsinki : University of Helsinki, 2000. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/fagerudd/.
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Malaguarnera, Giulia Anna. "Diabetic retinopathy and Type 3 Diabetes Role of Homocysteine". Doctoral thesis, Università di Catania, 2015. http://hdl.handle.net/10761/3950.
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Homocysteine is a sulphur amino acid converted to methionine to a remethylation pathway and to cysteine via transulphuration patway. Its level in the blood increase with age and are associated with several pathologies: cancer, autoimmune disease, cardiovascular and neurodegenerative disorders.
The present thesis has focused on the study of the relationship between elevated levels of homocysteine and the deficiency of his metabolites, focusing on folate, in the severity of diabetic retinopathy (non- proliferative and proliferative).
Then it had been investigated whether retinal Hcy is associated with retinal neurodegeneration. Histopathological, molecular, and biochemical abnormalities have commonalities in Diabetes and Alzheimer s Disease (AD), which has lead to AD recently termed as "Type 3 Diabetes". Therefore, the present study has focused to evaluate the role of homocysteine in animal models of Type 2 Diabetes (Goto-Kakizaki (GK) rats) and Alzheimer Disease (TASTPM transgenic mice).
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MALAGUARNERA, GIULIA ANNA MARIA. "Diabetic retinopathy and Type 3 Diabetes Role of Homocysteine". Doctoral thesis, Università degli studi di Catania, 2015. http://hdl.handle.net/20.500.11769/490906.
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Homocysteine is a sulphur amino acid converted to methionine to a remethylation pathway and to cysteine via transulphuration patway. Its level in the blood increase with age and are associated with several pathologies: cancer, autoimmune disease, cardiovascular and neurodegenerative disorders. The present thesis has focused on the study of the relationship between elevated levels of homocysteine and the deficiency of his metabolites, focusing on folate, in the severity of diabetic retinopathy (non- proliferative and proliferative). Then it had been investigated whether retinal Hcy is associated with retinal neurodegeneration. Histopathological, molecular, and biochemical abnormalities have commonalities in Diabetes and Alzheimer s Disease (AD), which has lead to AD recently termed as "Type 3 Diabetes". Therefore, the present study has focused to evaluate the role of homocysteine in animal models of Type 2 Diabetes (Goto-Kakizaki (GK) rats) and Alzheimer Disease (TASTPM transgenic mice).
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Mitev, Nikolay. "E-health for people with diabetes : Adoption and use of diabetes self-management applications among diabetics in Bulgaria". Thesis, Internationella Handelshögskolan, Högskolan i Jönköping, IHH, Informatik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-39081.
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The purpose of this thesis is to study the level of understanding of e-health applications among users with diabetes in Bulgaria, to find out how they use those applications, and to provide knowledge on what m-health applications provide to people with diabetes, and what they actually need. This research used TAM variables combined with Innovation Diffusion Theory to produce knowledge on technology acceptance. Therefore, the factors of relative advantage, compatibility, complexity, trialability and observability will be used to determine perceived usefulness, perceived ease of use and behavior intention to use a technology. This research was intended to gather information on the use of diabetes self-management mobile apps in a standardized manner. The instrument used for the survey, a questionnaire, aimed to provide information on the use and experience of mobile health apps for managing diabetes. The final online survey was completed by 71 participants, 38 of which were female, 28 were male and 7 were of non-specified gender. The introductory stage of the survey showed that most of the respondents were between the ages of 31 to 40 years old (28.2 %), and that the largest part of the population sample has been diabetic for five years (32.4%). By taking into consideration the results, it can be said that 74.6% of relative advantage correspond to very high perceived usefulness on behalf of the respondents. And a score of 53.5% shows that the people who took part in the survey exhibit high perceived ease of use of the mobile applications. This concludes that initially upon using diabetes self-management applications, the respondent’s exhibit high behavioral intention to do so and due to that the applications are not defined as complex, they are suitable for constant use.
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Tahiliani, Arunkumar Govindram. "Studies on diabetes-induced myocardial alterations in streptozotocin diabetic rats". Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/25979.
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Diabetes is known to result in a large number of alterations which affect various systems and organs. One of the more prominent disorders associated with diabetes is that of cardiac disease. Clinically, diabetics
suffer from morbidity and mortality of cardiac origin to a greater extent than the nondiabetic population. Various functional studies have also revealed that the efficiency of diabetic hearts to function as pumps is lower than that of normal hearts. Experimentally, myocardial function of either rats or dogs made diabetic with either streptozotocin (STZ) or alloxan has been studied and a depression clearly demonstrated in both the species. The abnormalities of cardiac function in experimental diabetes are accompanied by depression of various enzyme systems in the heart. These include the ability of the sarcoplasmic reticulum (SR) to take up calcium; the myosin and actomyosin ATPase activities; and the Na⁺, K⁺ ATPase activity. All these changes can be prevented and reversed by insulin treatment suggesting that the myocardial problems seen in STZ or alloxan diabetic animals are due to diabetes and not direct toxicities of the drugs.
It is not known whether the beneficial effects of in vivo insulin treatment are due to its direct myocardial effects or whether they are secondary to its effects mediated via normalisation of metabolism in diabetic animals. Thus, in the first part of the present investigation, we examined the direct effects of insulin on hearts from either control or diabetic rats using the isolated working heart preparation. Rats made diabetic with STZ (55 mg/kg) were sacrificed either 3 days or 6 weeks after induction of the disease and their hearts isolated and perfused in the working heart mode. Glucose concentrations varying from 5mM to 20mM were used in the perfusion medium, either in the presence or absence of insulin (5mU/mL). Left ventricular function was expressed as left ventricular developed pressure (LVDP) and the rates of contraction and relaxation (positive and negative dP/dt respectively) at various left atrial filling pressures. Three days after injecting STZ into rats, the animals exhibited hypoinsulinemia, hyperglycemia and their body weights although not significantly different from those of control animals, tended to be lower than the body weights of controls. Animals treated in this manner did not exhibit depression of cardiac function when compared with the myocardial function of control rats. Hearts from control rats exposed to regular insulin in the presence of 5mM glucose exhibited values of contractility which were significantly greater as compared with those obtained from control rat hearts not exposed to the hormone. When insulin was perfused along with a higher concentration of glucose (10mM), function of control rat hearts was affected to a significant extent. As opposed to the effects on control rat hearts, insulin failed to increase contractility in hearts from 3 day diabetic rats when either 5 or 10mM glucose was used in the perfusion medium.
The study was then repeated using animals which had been diabetic for six weeks. At the time of sacrifice, these animals were hypoinsulinemic, hyperglycemic and weighed significantly less than their age-matched controls. Analysis of cardiac function revealed a significant depression in diabetic rats as compared with controls. Increasing glucose concentrations from 5 to 20mM in the perfusion medium did not affect the function of either control or diabetic rat hearts. Perfusion with regular insulin increased contractility in control rat hearts; the increase in contractility was not affected by increasing the glucose concentration from 5 to 10mM. However, contractility of diabetic rat hearts was not affected by insulin perfusion when either 5 or 10mM glucose was used in the perfusion medium. In order to eliminate the possibility of involvement of glucagon (which may contaminate commercial insulin preparations) in the effects of insulin on control rat hearts, part of the study was repeated using glucagon - free insulin. While the glucagon - free insulin increased contractility in control rat hearts, diabetic rat hearts were not affected. These results are identical to those obtained with regular insulin, suggesting that the effects of insulin observed were due to insulin itself.
Although insulin treatment prevents and reverses diabetes - induced myocardial alterations in the rats, due to its widespread metabolic effects, it is not a good tool for investigating the specific factors which cause the cardiac abnormalities. In addition, a major problem with insulin treatment clinically is the fact that hypoglycemia can be associated with it, inadequate control occurs in some diabetics and secondary complications, such as myocardial problems, occur despite insulin treatment. It is thus desirable to have treatments which selectively affect certain aspects of diabetes so that the suspected underlying causes can be corrected specifically and their significance in causing the myocardial problems assessed. It would also be useful to have drug treatments which could either substitute for insulin or could be used in addition to the peptide. We have thus studied the effectiveness of certain treatments in preventing diabetes - induced myocardial alterations. The first one used was methyl palmoxirate, a fatty acid analog which is reported to reduce blood glucose levels in diabetic rats and dogs. The glucose - lowering effect is mediated via inhibition of fatty acid metabolism due to inhibition of carnitine acyl transferase resulting in inhibition of acyl carnitine formation and eventually inhibition of fatty acid transport across the mitochondrial membrane. Rats were treated with the drug (25mg/kg/day p.o.) three days after they were injected with either STZ or buffer. The treatment was carried out for 6 weeks and cardiac performance was then assesed. Untreated and treated diabetic rats were hypoinsulinemic, hyperglycemic and hyperlipedemic at the time of sacrifice. Cardiac function, which was depressed in diabetic animals, was still depressed despite the methyl palmoxirate treatment. However, the ability of the myocardial sarcoplasmic reticulum (SR) to take up calcium, which was depressed in diabetic rats, was normal in treated diabetic rats. Also, the levels of long chain acyl carnitines (LCAC) in the myocardial SR were normalised by methyl palmoxirate treatment in diabetic rats.
In an effort to normalise diabetes - induced myocardial alterations in rats, we then attempted a combination of either methyl palmoxirate or carnitine (as both can prevent the depression of SR calcium uptake) with thyroid hormone treatment (as it can normalise myosin ATPase depression in diabetic rat hearts). The treatment protocol was identical to that described above (30µg/kg/day s.c. T₃ was used). Although the general features of both control and diabetic animals were not affected by either of the combination treatments, cardiac dysfunction in diabetic rats was prevented by methyl palmoxirate and T₃ treatment. Carnitine and T₃ treatment, on the other hand, affected the function of diabetic rat hearts only at the lower left atrial filling pressures. These results suggest that the combination treatment of methyl palmoxirate and T₃ affect parameters besides SR calcium uptake and myosin ATPase. This is because the combination of carnitine and T₃, which also supposedly affects same parameters as the other combination, could not prevent the myocardial alterations. One of the possible reasons for the effectiveness of the combination of methyl palmoxirate and T₃ could be that animals treated with methyl palmoxirate derived at least part of their metabolic energy (especially at higher left atrial filling pressures) from glucose and thus reduced the oxygen demand at higher filling pressures as opposed to the untreated diabetic rat hearts which depended completely on fatty acids for their metabolic energy demands.Pharmaceutical Sciences, Faculty of
Graduate
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Pilkauskienė, Ramutė. "Pediatrų endokrinologų, slaugytojų ir tėvų požiūris į šeimos problemas, vaikui susirgus cukriniu diabetu". Master's thesis, Lithuanian Academic Libraries Network (LABT), 2005. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2005~D_20050614_123532-83061.
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Summary
The diabetes is а chronic non-infectious disease that touches people from the birth to the old age. Children and young people mostly suffer from diabetes type 1. Тhe morbidity in this disease is increasing not only in Lithuania but also in the whole world. In 1980, 30 million people in the world suffered from the diabetes, while in 2000 there were already 100 million such people. As the number of children suffering from the diabetes is increasing, it is very important to understand what influence to their psycho-social development is caused bу this disease, how the relationship between the child and his or her family changes, and how the relationship between the diabetics, their family and the environment develops.
When а child falls ill with the diabetes, the family faces many questions, and the life splits into two parts: before the disease and after its diagnosing. А child who suffers from diabetes of type 1 has to make insulin injections during аll his or her life, to check the quantity of glucose in the blood, to observe nutrition recommendations. The family whose child falls ill with an incurable disease experiences the process of loss. The duration of its stages and its succession depends of the psychosocial state of the family.
The treatment of children's diabetes is also complicated due to psychological peculiarities of the age of children. Children of different ages can perform different tasks and to undertake different duties. Eventually, а child will bе... [to full text]
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Simpson, Sandra Marcia. "Walking the line managing type 2 diabetes : a grounded theory study of part-Europeans from Fiji : a thesis submitted in partial fulfilment of the requirement for the degree of Master in Health Science, Department of Nursing Studies, Auckland University of Technology, November 2004". Full thesis. Abstract, 2004.
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Johansson, Madelene. "Barn med diabetes : Hur kan diabetes påverka inlärningsförmågan?" Thesis, Karlstad University, Faculty of Arts and Education, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-577.
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Att drabbas av en kronisk sjukdom som diabetes påverkar vardagen för resten av livet. Allt fler barn drabbas av diabetes och som lärare innebär det att chansen att få möta dessa barn i skolan ökar. För barn i skolåldern kan sjukdomen påverka skolarbetet. Syftet med denna rapport är att undersöka hur diabetes påverkar inlärningsförmågan, samt undersöka vad en lärare behöver förstå angående barn med diabetes. Genom att intervjua en flicka med diabetes på mellanstadiet, hennes föräldrar och klassföreståndare har jag fått en personlig bild av hur det är att leva med diabetes i praktiken. De kan alla vittna om hur diabetes påverkar förmågan att koncentrera sig och att lära. Intervjuer med två diabetessköterskor visar att svaren från de andra respondenterna delvis kan tas för allmänna bland barn med diabetes. Denna rapport visar att diabetes har inverkan på inlärningsförmågan. Högt, lågt och svängande blodsocker gör diabetikern trött och okoncentrerad. Det är diabetikern själv, med hjälp av föräldrar och sjukvård, som ansvarar för att sjukdomen sköts på ett bra sätt. För läraren gäller det att ha en god förståelse för diabetessjukdomens påverkan på skolarbetet.
To suffer from a chronic disease such as diabetes affects everyday life for the rest of life. More and more children suffer from diabetes and the chances for teachers to meet one of these children in school are increasing. A child’s ability to perform at school can be affected by this disease. The purpose of this report is to investigate how diabetes affects the ability to learn and what a teacher must understand about children who have diabetes. I have learnt what it’s like to live with diabetes by interviewing a girl in middle school, her parents and her teacher. They can all testify about how diabetes affects the ability to focus and learn. Interviews with two nurses confirm that diabetes can have this effect on children. This report shows that diabetes affects the ability to learn. High, low and turning levels of blood sugar makes a diabetic tired and unfocused. The diabetic assisted by her parents and the medical treatment is responsible for handling the disease. The teacher however must understand how diabetes affects a child’s ability to perform at school.
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Swan, Wendy Elizabeth. "Diabetes prevention in women with previous gestational diabetes /". Connect to thesis, 2008. http://repository.unimelb.edu.au/10187/5742.
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Nordwall, Maria. "Long term complications in juvenile diabetes mellitus". Doctoral thesis, Linköping : Univ, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-6377.
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Vindedzis, Sally Ann. "The relationship between low blood thiamin levels in diabetes to thiamin intake and diabetic control". Thesis, Curtin University, 2008. http://hdl.handle.net/20.500.11937/248.
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Mild thiamin deficiency is prevalent in diabetes, and high dose thiamin ameliorates some diabetic complications, but there are no definitive studies addressing thiamin intake, diabetes control and thiamin status in diabetes. Subjects were 113 people with diabetes (58 type 1, 55 type 2), 43 with and 70 without thiamin supplementation. Dietary thiamin was estimated by 24-hour recall, diabetes control by HbA1c. Age, BMI, albumin excretion, activity level and smoking status did not correlate with red cell thiamin (RCT) in either group. RCT correlated with serum thiamin (ST) (p < 0.01). In those unsupplemented, adequate dietary thiamin did not ensure normal RCT, with 15.7 % of subjects below the reference range. Supplementation to intake > 4 mg/d, was significantly associated with normal RCT (p = 0.028), with 97.7% of supplemented subjects having normal RCT. Supplementation was also significantly associated with elevated serum thiamin 24 hours post supplementation, contrary to other reports. HbA1c was not significantly associated with RCT. Conclusions: In diabetes, adequate dietary thiamin does not ensure normal red cell thiamin, but supplementation to > 4 mg/day does, raising questions about actual thiamin requirements in diabetes and supporting evidence that thiamin deficiency in diabetes is not primarily due to dietary deficiency. Diabetes control was not significantly related to thiamin status.
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Nordenhäll, Tove. "Gåtan Diabetes". Thesis, Södertörn University College, School of Discourse Studies, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-217.
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McKnight, Sarah. "Diabetes Camp". ScholarWorks@UNO, 2008. http://scholarworks.uno.edu/td/708.
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Every summer Camp Hopewell in Oxford, Mississippi hosts its annual summer camps. Over the course of a week, kids between the ages of seven and fifteen run, play, hike, and canoe. It's the pretty standard summer camp fair, but there is something that makes a week at Camp Hopewell different. Every child that comes to camp has been diagnosed with Type I Diabetes. Some have had it for years and consider camp their second home while some have just been diagnosed and still live in fear of their condition. For this one week, however, they all have something in common, and while they eat, sleep, and play, they learn to take care of their own Diabetes. Diabetes Camp is a 25 minute documentary film that is meant to show audiences the remarkable occurrences at Camp Hopewell through the eyes and voices of the campers and the staff that work there.
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Cabrera, Mario, e María Inés Giagnoni. "Diabetes gestacional". Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Escuela de Enfermería, 2011. http://bdigital.uncu.edu.ar/6022.
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El presente trabajo de investigación se realizó en el Centro de Salud Nº 146, ubicado en el distrito Los Campamentos, departamento de Rivadavia. Se trabajó con 65 mujeres embarazadas quienes asistieron al Centro de Salud en los años 2009 y 2010. Los objetivos de este trabajo son: conocer los diferentes factores que inciden en la aparición de diabetes gestacional, valorar los conocimientos que poseen las pacientes embarazadas sobre diabetes gestacional y determinar las diferentes complicaciones que surgen en la embarazada.Fil: Cabrera, Mario. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Escuela de Enfermería..
Fil: Giagnoni, María Inés. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Escuela de Enfermería..
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Alvarado, Silvana Carina, Vanesa Cruz e Jhenny Herrera. "Diabetes gestacional". Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Escuela de Enfermería, 2018. http://bdigital.uncu.edu.ar/11871.
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El presente trabajo de investigación se realizó en el 2do piso de maternidad del Hospital Luis Lagomaggiore en la ciudad de Mendoza, Argentina. Se trabajó con 50 mujeres embarazadas, las cuales, estuvieron internadas desde el mes de junio al mes de septiembre del 2017, teniendo como finalidad detectar los conocimientos previos que poseen las embarazadas con diabetes gestacional sobre los riesgos y las complicaciones de su patología.
Objetivos:determinar los conocimientos previos que poseen las embarazadas con diabetes gestacional sobre los riesgos y las complicaciones de su patología; indagar los conocimientos previos que poseen las embarazadas con diabetes gestacional sobre las complicaciones y los riesgos de esta patología; enunciar los factores de riesgo y las complicaciones; caracterizar el nivel social, económico y cultural de las embarazadas con diabetes gestacional; conocer si recibió información sobre los cuidados de su patología
Es un estudio con diseño de tipo mixto: cuantitativo y cualitativo, descriptivo y retrospectivo. Población y muestra: 50 pacientes embarazadas del servicio de maternidad de 2do piso del Hospital L. Lagomaggiore. Se utiliza un cuestionario con preguntas cerradas.
Resultados: Del total de población de estudio, se observo que el 50% de la muestra (25 casos) correspondieron a embarazadas del rango de 21 a 30 años de edad, con un predominio del 56% de embarazadas con 2 a 4 gestas, solamente el 12% eran primigestas. Se observó un predominio del 62% de los casos de embarazos cursan entre la semanas 25 a 36 de gestación, el 46% de las gestantes tiene estudios secundarios incompletos y el 98% sabe leer y escribir, el 46% pertenecen a un grupo familiar múltiple (padre-madre-hijos-otros familiares), el 66% no trabaja, el 36% de la población gestante no presenta antecedentes de patologías previas y el 35% tenía DBT-G.
Se obtuvo que 44% de los padres de las embarazadas no refieren antecedentes patológicos y el 58% de las madres de las embarazadas no presenta antecedentes de enfermedad, el 46% de la población conoce la diabetes gestacional y el 44% no conoce ningún tipo de diabetes, el 48% conoce la complicación de parto prematuro como consecuencia de la diabetes gestacional y un 44% no tiene conocimiento de dichas complicaciones maternas, un 46% desconoce las complicaciones fetales y el 66% fueron diagnosticadas con diabetes gestacional, el 70% fue diagnosticada durante el embarazo, el 42% fue diagnosticada entre la semana 31 a la 40 de gestación y el 84% de las gravídicas recibió información del profesional médico.
Conclusiones: Detectar la diabetes gestacional, informando a las embarazadas de manera correcta, permitirá cursar un embarazo sin demasiados sobresaltos, la salud de la embarazada y el bebé depende de su ámbito familiar y de su atención en los institutos de salud, donde la enfermería tiene un rol muy importante.
Recomendaciones: La educación se debe adaptar en cada paciente de manera particular. Las embarazadas, deberían tener charlas educativas desde enfermería, durante su internación, donde se las pueda evaluar para la continuidad del tratamiento en el hogar.Fil: Alvarado, Silvana Carina.
Fil: Cruz, Vanesa.
Fil: Herrera, Jhenny.
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van, Netten Jaap J., Peter A. Lazzarini, David G. Armstrong, Sicco A. Bus, Robert Fitridge, Keith Harding, Ewan Kinnear et al. "Diabetic Foot Australia guideline on footwear for people with diabetes". BIOMED CENTRAL LTD, 2018. http://hdl.handle.net/10150/626601.
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Background: The aim of this paper was to create an updated Australian guideline on footwear for people with diabetes. Methods: We reviewed new footwear publications, (international guidelines, and consensus expert opinion alongside the 2013 Australian footwear guideline to formulate updated recommendations. Result: We recommend health professionals managing people with diabetes should: (1) Advise people with diabetes to wear footwear that fits, protects and accommodates the shape of their feet. (2) Advise people with diabetes to always wear socks within their footwear, in order to reduce shear and friction. (3) Educate people with diabetes, their relatives and caregivers on the importance of wearing appropriate footwear to prevent foot ulceration. (4) Instruct people with diabetes at intermediate-or high-risk of foot ulceration to obtain footwear from an appropriately trained professional to ensure it fits, protects and accommodates the shape of their feet. (5) Motivate people with diabetes at intermediate-or high-risk of foot ulceration to wear their footwear at all times, both indoors and outdoors. (6) Motivate people with diabetes at intermediate-or high-risk of foot ulceration (or their relatives and caregivers) to check their footwear, each time before wearing, to ensure that there are no foreign objects in, or penetrating, the footwear; and check their feet, each time their footwear is removed, to ensure there are no signs of abnormal pressure, trauma or ulceration. (7) For people with a foot deformity or pre-ulcerative lesion, consider prescribing medical grade footwear, which may include custom-made in-shoe orthoses or insoles. (8) For people with a healed plantar foot ulcer, prescribe medical grade footwear with custom-made in-shoe orthoses or insoles with a demonstrated plantar pressure relieving effect at high-risk areas. (9) Review prescribed footwear every three months to ensure it still fits adequately, protects, and supports the foot. (10) For people with a plantar diabetic foot ulcer, footwear is not specifically recommended for treatment; prescribe appropriate offloading devices to heal these ulcers. Conclusions: This guideline contains 10 key recommendations to guide health professionals in selecting the most appropriate footwear to meet the specific foot risk needs of an individual with diabetes.
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Åkerman, Linda. "Aspects of the Pre-Diabetic Period in Type 1 Diabetes". Doctoral thesis, Linköpings universitet, Avdelningen för kliniska vetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-132171.
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Type 1 diabetes (T1D) is an autoimmune disease characterized by insulin deficiency, due to immune-mediated destruction of beta cells. Current knowledge regarding the period preceding disease onset comes, to a large extent, from studying risk cohorts based on relatives of T1D-patients, as they have an increased disease risk. Among T1D patients in general, however, few have the disease in their immediate family. It is therefore important to study risk cohorts from the general population as well. An ongoing autoimmune reaction can often be seen in the blood long before disease onset, by detection of autoantibodies directed towards beta cell antigens. By autoantibody screening among participants in the ABIS (All Babies in the South-east of Sweden) cohort, we could identify a group of children from the general population with increased risk for T1D, positive for multiple autoantibodies. They were enrolled in a 2-year prospective follow-up aiming to characterize the prediabetic period and to identify factors indicative of progression/non-progression to T1D. We assessed glucose homeostasis and autoantibody titers over time, and searched for risk-biomarkers by analyzing the expression of immune-related genes (Th1-Th2-Th3) in peripheral blood mononuclear cells (PBMC) from these children, in comparison to healthy children and newly diagnosed T1D patients. In the same groups we also compared serum micro RNA (miRNA) profiles, knowing that miRNA molecules have desirable biomarker properties. We found that two specific autoantibodies, IA2A and ZnT8A, were detected at higher concentrations in risk-individuals who progressed to overt T1D during or after the follow-up period, compared to those who still have not. We also observed disturbed glucose homeostasis long before onset in the progressors, but it was seen among those who remain symptom free as well. Further, we found support for the possible role of insulin resistance as an accelerator of the disease process. For gene expression and serum miRNA, few differences were observed between risk-individuals and healthy children overall. However, for PBMC gene expression and serum miRNA both, there were associations to beta cell function and glucose homeostasis, and for miRNA also to islet autoantibodies. Although specific profiles for prediction of disease onset or identification of risk-individuals could not be found, these results are interesting and deserve to be evaluated further. As part of another sub-study within ABIS, the effects of physical activity on glucose homeostasis were assessed in healthy schoolchildren. The level of physical activity, measured by pedometers, was related to insulin resistance and beta cell-stress, and decreased physical activity was associated with increased insulin resistance and load on the insulin-producing beta cells, already at school-age.
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Dzivakwe, Vanessa G. "Psychosocial Determinants of Diabetic Control and Satisfaction with Diabetes Care". Thesis, University of North Texas, 2011. https://digital.library.unt.edu/ark:/67531/metadc67977/.
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Diabetes mellitus affects 7.8% of the American population. National health statistic data and other research shows that racial/ethnic disparities exist in terms of prevalence and treatment outcomes. The present study investigated the role of patient health beliefs (i.e., locus of control, self-efficacy) and the doctor-patient relationship (e.g., satisfaction and collaboration with health care provider), as relative predictors of diabetic control (i.e., HbA1c levels) and overall satisfaction with diabetes care, in older adult participants with diabetes. Demographic, psychosocial, and diabetes-related data from the Health and Retirement Study (HRS) 2003 Diabetes Study were analyzed to compare treatment outcomes among non-Hispanic White, non-Hispanic Black, and Hispanic individuals with various types of diabetes. Non-Hispanic White individuals exhibited better diabetic control than their minority counterparts (F(2, 592) = 7.60, p < .001); however, no significant group differences were noted in terms of psychosocial factors. Diabetic control was best predicted by time since diagnosis (β = -.21, p < .001), satisfaction with diabetes self-care (β = .19, p < .001) and age (β = .12, p < .01). In addition, satisfaction with provider care was best predicted by perceived collaboration with provider (β = .44, p < .001), satisfaction with diabetes self-care (β = .22, p < .001) and diabetes self-efficacy (β = .08, p < .05). Recommendations for future research were discussed.
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Gravely, Marie R. "West Virginia registered dietitians knowledge and attitudes of diabetes care". Huntington, WV : [Marshall University Libraries], 2002. http://www.marshall.edu/etd/descript.asp?ref=157.
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Van, Zyl Danie G. "The efficacy of an intervention program aimed at diabetes care physicians regarding quality of diabetes care at a tertiary care hospital". Diss., University of Pretoria, 2003. http://hdl.handle.net/2263/27097.
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Roberts, Clare Louise. "Associations between satisfaction with diabetes care, diabetic control and psychological variables in adolescents with type I insulin dependent diabetes mellitus". Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/26887.
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Insulin Dependent Diabetes Mellitus (IDDM) is a life-long condition, which is the third most common chronic illness in young people (Metcalfe & Baum, 1991). Management of the illness includes a daily regimen of blood testing, insulin injections and careful balancing of diet and exercise (Shillitoe, 1995). In adolescence, diabetes control often deteriorates (Brink, 1997; Jacobson, Hauser, Wolsdorf, Houlihan, Herskowitz, Wertlieb & Watt, 1987). This consequently can have a detrimental effect on future physical health (Diabetes Control and Complications Trial, 1994). A large amount of research has sought to identify the relevant variables that are indicative of good and poor adjustment to chronic illness (for example, Eiser, 1990a). Several models have been developed, including the Risk and Resilience Model (Wallander & Varni, 1998), which was used to guide this study. It is hypothesised that patient satisfaction with diabetes care will act as a resilience factor and therefore be associated with better psychological well-being. Eighty-three young people between the ages of 14 and 18 attending diabetes outpatient clinics in the Lothian area were assessed, using standardised measures of patient satisfaction, quality of life, psychological well-being and adaptation to diabetes. The relationships between these variables, diabetic control and the effects of age, gender and time since diagnosis were calculated. Results are discussed in relation to the planning and evaluation of medical and psychological services for adolescents with diabetes. Finally, methodological weaknesses are highlighted and implications for future research discussed.
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Dornhorst, Anne. "Gestational diabetes : a model of non-insulin dependent diabetes". Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334887.
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Ferreira, Filipa Cristina Costa. "A Diabetes - Principais Parâmetros para o Controlo da Diabetes". Master's thesis, Faculdade de Ciências Médicas. UNL, 2013. http://hdl.handle.net/10362/10001.
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RESUMO: A Diabetes Mellitus é uma doença metabólica crónica, com deficiência a nível do metabolismo dos hidratos de carbono, lípidos e proteínas, resultante de deficiências na secreção ou ação da insulina, ou de ambas, que quando não tratada antecipadamente e de modo conveniente, pode ter consequências muito graves. Dado a incidência a nível mundial da Diabetes Mellitus, torna-se de elevada importância avaliar toda a sua envolvência e estudar bem quais os critérios a ter em consideração. Este trabalho propõe-se estudar para além dos parâmetros bioquímicos relacionados com a doença - Glicose e Hemoglobina Glicada A1c (HbA1c), analisar os resultados dos últimos cinco anos (2008-2012) dos ensaios interlaboratoriais do PNAEQ, do Departamento de Epidemiologia, do Instituto Nacional de Saúde Dr. Ricardo Jorge. Foram também analisadas as metodologias utilizadas e as variações interlaboratoriais, de forma a entender qual ou quais são os parâmetros mais adequados para o seu diagnóstico e controlo.
Este estudo utilizou a população de laboratórios portugueses, públicos e privados, de Portugal Continental e Ilhas, um laboratório de Angola e outro de Macau que se inscreveram no PNAEQ nestes cinco anos, sendo a amostra composta pelo n.º de participações. No programa de Química Clinica foram distribuídas 38 amostras e no programa de HbA1c foram distribuídas 22 amostras.
Para a glicose, o nível de desempenho nos ensaios é na globalidade das amostras de Excelente, no entanto verifica-se que sempre que a concentração da amostra é de nível patológico, que a maioria dos ensaios o desempenho foi inferior – Bom. O método de eleição e com CV% mais baixos foi o método da hexoquinase. Para a HbA1c, o nível de desempenho nos ensaios é na globalidade das amostras de Excelente. O método de eleição e com CV% mais baixos foi o método de HPLC. O CV% para a glicose ronda desde 2010 a 2012, os 3% e para a HbA1c foi de aproximadamente 4,0% em 2012.
A HbA1c tem mostrado ser uma ferramenta muito útil, importante e robusta na monitorização da Diabetes, sendo hoje em dia quase sempre requisitada em análises de rotina a diabéticos de modo a prevenir complicações que possam vir a acorrer. No futuro poderá ser um importante, senão o parâmetro de futuro, para o diagnóstico da Diabetes, no entanto, mesmo já tendo sido muito trabalhada a sua padronização, ainda existem questões por responder como quais são na realidade todos os seus interferentes, qual a verdadeira relação da HbA1c com a glicose média estimada, em todas as populações e com estudos epidemiológicos. Também a própria educação do diabético e clínico deve ser aprimorada, pelo que neste momento as PTGO e os doseamentos de glicose em jejum devem ser utilizados e encontrando-se a Norma da DGS N.º 033/2011 de acordo com as necessidades e com o estado da arte deste parâmetro. A implementação da glicose média estimada será uma mais-valia na monitorização dos diabéticos pelo que deverá ser uma das prioridades a ter em conta no futuro desta padronização, uniformizando a decisão clinica baseada nela e minimizando a dificuldade de interpretação de resultados de laboratório para laboratório. --------------ABSTRACT: Diabetes Mellitus is a chronic metabolic disease, with a deficit in the metabolism of carbohydrates, lipids and proteins, resulting from deficiencies in insulin secretion or action, or both, which if, when not early treated in a proper way, may result in very serious consequences. Given the worldwide incidence of diabetes mellitus, it is highly important to evaluate all its background and study specifically all the criteria to take into consideration. The aim of this thesis is to study and evaluate beyond the biochemical parameters related to the disease - Glucose and Glycated Haemoglobin A1c (HbA1c), analyze the results of the last five years (2008-2012) of the PNAEQ interlaboratorial tests, in the Department of Epidemiology of National Institute of Health Dr. Ricardo Jorge. It is also intended to analyze the methodologies used and the interlaboratorial variations, in order to understand the most suitable parameters for the diagnosis and control.
This study was based in a population of Portuguese laboratories, public and private, of Portugal mainland and islands, a laboratory of Angola and other from Macau, who enrolled in PNAEQ in these five years, and the sample was composed by the n. º of holdings. In the Clinical Chemistry Program there were distributed 38 samples and in the program HbA1c were distributed 22 samples.
For glucose, the level of performance in the total nº of the samples was Excellent; however, it was found that when the concentration level of the sample was pathological, in most of the tests the performance was Good. The most preferred method with the lowest CV% is the hexokinase method. For the HbA1c, as a whole, the samples’ tests were Excellent, at the level of performance. The method of election with the lower CV% was the HPLC. The CV% for glucose was around 3%, from 2010 to 2012 and the HbA1c was approximately 4.0% in 2012.
The HbA1c method has demonstrated to be a very useful tool, important and robust for monitoring diabetes, being nowadays, almost always required in routine analysis to prevent future complications. In the future it may be an important parameter, if not the most important, for the diagnosis of diabetes. However, despite it has already been standardized, there are still some questions that need to be answered, such as, which are in fact all their interferences, which is the true connection of HbA1c, when compared with the estimated average glucose, in all populations and epidemiological studies. Moreover, the education of the patient and the doctor concerning diabetes should be improved. Nowadays, the Oral Glucose Tolerance Test (OGTT) and fasting glucose determinations should be used and, the needs and the state of the art of this parameter, should be in accordance with the Standard DGS N. º 033/2011.
The Implementation of the estimated average glucose will be an added value in monitoring diabetics and, therefore, should be a priority to consider in its future standardization and clinical decision based on it, will be uniform and the difficulty of interpreting results from laboratory to laboratory will be minimal.
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Brown, Remona Lysa. "Assessing for Awareness and Knowledge Regarding Diabetes in Pre-Diabetes Obese Patients". ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4045.
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Over the past few decades, there has been an increase in prevalence of diabetes in the United States. Prevention of diabetes and improving patients' knowledge and awareness of diabetes are crucial for healthcare providers. Using the Health Belief Model (HBM) as a theoretical foundation, the student used the National Diabetes Prevention Program (NDPP) from the Centers for Disease Control and Prevention (CDC), to improve awareness and knowledge of diabetes among obese individuals with prediabetes. The key research question of this project was to determine whether the patients' diabetes knowledge and awareness improved after the NDPP program. A convenience sample of 30 participants was recruited from patients seeking care at a family practice clinic. Data collection was conducted using the Michigan Diabetes Research and Training Center's Diabetes Knowledge Test (DKT). Pretest and posttests were used to evaluate improvement in the participants' knowledge and awareness after administration of education sessions. The t-tests indicated a significant improvement in the patients' knowledge (p < 0.000) and awareness (p < 0.000) of diabetes after the NDPP program. Thus, the NDPP program was effective in improving the patients' diabetes knowledge and awareness. The nationwide adoption of the NDPP program was recommended to reduce the rate of diabetes among high risk individuals. The implication of this Doctor of Nursing Practice (DNP) project to social change was that improving knowledge and awareness of diabetes among obese patients with prediabetes would increase their participation in lifestyle and behavioral modification programs, thus, improving the control of blood sugar levels.
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Petropoulos, Ioannis. "Corneal nerve pathology in diabetes". Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/corneal-nerve-pathology-in-diabetes(9912e560-1032-45cd-8f0a-0477d6605a98).html.
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The accurate detection and quantification of human diabetic somatic polyneuropathy (DSPN) are important to define at risk patients, anticipate deterioration, and assess new therapies. Current methods lack sensitivity, require expert assessment and have major shortcomings when employed to define therapeutic efficacy. In recent years, in vivo corneal confocal microscopy (IVCCM) has shown potential as a surrogate endpoint for DSPN.This study aims to investigate fundamental aspects of IVCCM such as repeatability and optimal scanning methodology and establish changes in corneal nerve morphology in relation to the severity of DSPN and regeneration in response to normalisation of hyperglycaemia. Furthermore, it aims to provide a novel fully automated image analysis algorithm for the quantification of corneal nerve morphology and establish the diagnostic ability of CCM.IVCCM shows high repeatability which is enhanced with more experienced observers. Central corneal innervation is comparable to adjacent peripheral innervation in mild diabetic neuropathy but the central cornea may be more sensitive to change. Corneal nerve loss is symmetrical and progressive with increasing neuropathic severity and corneal nerves show significant regenerative capacity following rapid normalisation of glycaemic control after simultaneous pancreas and kidney transplantation. The novel image analysis algorithm strongly correlates with human expert annotation and therefore represents a rapid, objective and repeatable means of assessing corneal nerve morphology. Automated image quantification may replace human manual assessment with high diagnostic validity for DSPN.
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Maher, Kathryn. "Assessment of Diabetes Regimen Disease Care in Youth with Type 1 Diabetes via the Diabetes Behavior Rating Scale and the 24-Hour Diabetes Interview". VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/185.
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The psychometric properties of two measures of diabetes disease care, the Diabetes Behavior Rating Scale (DBRS) and the 24-hr Diabetes Interview (24-hr) were evaluated. The 24-hr is a widely used, structured interview while the DBRS is a self-administered, fixed-choice questionnaire. Both measures were administered to 250 youth with Type 1 Diabetes (aged 11–14 years) and their parents. Overall, both measures demonstrate adequate psychometric properties. The DBRS and the 24-hr demonstrated good incremental validity and low convergent validity with each adding significant additive value. Both measures demonstrated good concurrent validity with HbA1c. As expected, scores on the 24-hr demonstrated less than adequate test-retest reliability and both measures demonstrated low parent/youth agreement. Interestingly, external validity analyses demonstrated DBRS scores were moderately related to HbA1c in non-pump but not pump regimens, while the 24-hr displayed acceptable external validity. Only three subscales significantly contributed to HbA1c suggesting a more parsimonious assessment measure. This novel, brief combination could prove efficacious for clinical practice.
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Lopes, Daniela Filipa Narciso Ortiz. "Diabetes, conhecer para melhor viver: capacitação da pessoa com diabetes". Master's thesis, Instituto Politécnico de Setúbal. Escola Superior de Saúde, 2019. http://hdl.handle.net/10400.26/29236.
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Mestrado em Enfermagem Comunitária e de Saúde Pública, Área de especialização: Enfermagem Comunitária e de Saúde PúblicaEste relatório foi desenvolvido no âmbito da realização de um projeto de intervenção comunitária no concelho de Portimão dirigido aos utentes diabéticos, utilizando a metodologia de planeamento em saúde. Para tal, foi inicialmente realizado um diagnóstico de saúde que permitiu identificar a Diabetes Mellitus como uma área problemática desta população. O objetivo deste projeto de inter-venção foi capacitar para o autocuidado os utentes diabéticos tipo 2 de determinada equipa de uma USF, validando, também, a adesão a este tipo de iniciativas. Foi aplicado um instrumento de avalia-ção validado e direcionado para a temática e foram realizadas sessões de educação para a saúde. A adesão às sessões de educação para a saúde mostrou-se satisfatória. Após a realização das sessões de educação para a saúde e análise do instrumento de avaliação validou-se a importância de dar continuidade a este projeto de capacitação da pessoa diabética.
This report was developed in the context of the implementation of a community intervention project in the county of Portimão for diabetic users, using the methodology of health planning. To that end, a health diagnosis was initially made to identify Diabetes Mellitus as a problematic area of this population. The objective of this intervention project was to qualify self-care for type 2 diabetic patients of a specific USF team, also validating adherence to this type of initiatives. A validated and directed evaluation instrument was applied to the theme and health education sessions were held. Adherence to health education sessions was satisfactory. After the health education sessions and analysis of the evaluation instrument, the importance of continuing this diabetic training project was validated.
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Wu, Di. "Discovery of glyco-biomarkers for diabetes and complications in diabetes". Thesis, University of Dundee, 2015. https://discovery.dundee.ac.uk/en/studentTheses/e2eee4c8-c74c-4fc6-8658-ab51ecd793de.
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Diabetes mellitus is a group of metabolic diseases characterized in disordered blood glucose levels with many altered genes, proteins and metabolites. The chronic hyperglycemia in diabetes damages organ systems and makes the diabetic patients vulnerable to one or more complications. The onset of diabetes and complications in diabetes are estimated to occur 5 to 10 years before the clinical diagnosis. The early diagnosis of diabetes prevents the damage and pathological progress of diabetes and complications in diabetes. The central hypothesis of this study was that the protein N-glycosylation pathway in diabetes might be influenced by elevated hexosamine flux in diabetes elevating sugar nucleotide levels. This, in turn, might affect the N-glycan branching pathway and result in detectable changes in plasma glycoprotein glycoforms. The aim of the study was to discover potential glyco-biomarkers for diabetes and complication in diabetes. Mass spectrometry based glycomic quantification was performed to look for alterations in N-glycan profiles between normal and diabetic plasma samples. Fucosylated N-glycans and intersected N-glycans were found to be up-regulated in diabetes with statistical significance. The elevated fucosylation in diabetes was verified at the glycosylation site level by quantitative Aleuria aurantia lectin (AAL) pull-down experiments. Fucosylated fetuin-A and α-1-acid glycoprotein were selected as candidate glyco-biomarkers. A lectin ELISA using F(abʹ)2 fragments as capture antibody was developed to validate the fucosylation changes by screening 20 normal and 20 diabetic patient plasma samples. We conclude that the fucosylation level of fetuin-A is a potential glyco-biomarker for diabetes. Additional work is necessary to see whether this glyco-biomarker correlates with any pathological complications of diabetes.
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Vindedzis, Sally Ann. "The relationship between low blood thiamin levels in diabetes to thiamin intake and diabetic control". Curtin University of Technology, School of Public Health, 2008. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=118316.
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Mild thiamin deficiency is prevalent in diabetes, and high dose thiamin ameliorates some diabetic complications, but there are no definitive studies addressing thiamin intake, diabetes control and thiamin status in diabetes. Subjects were 113 people with diabetes (58 type 1, 55 type 2), 43 with and 70 without thiamin supplementation. Dietary thiamin was estimated by 24-hour recall, diabetes control by HbA1c. Age, BMI, albumin excretion, activity level and smoking status did not correlate with red cell thiamin (RCT) in either group. RCT correlated with serum thiamin (ST) (p < 0.01). In those unsupplemented, adequate dietary thiamin did not ensure normal RCT, with 15.7 % of subjects below the reference range. Supplementation to intake > 4 mg/d, was significantly associated with normal RCT (p = 0.028), with 97.7% of supplemented subjects having normal RCT. Supplementation was also significantly associated with elevated serum thiamin 24 hours post supplementation, contrary to other reports. HbA1c was not significantly associated with RCT. Conclusions: In diabetes, adequate dietary thiamin does not ensure normal red cell thiamin, but supplementation to > 4 mg/day does, raising questions about actual thiamin requirements in diabetes and supporting evidence that thiamin deficiency in diabetes is not primarily due to dietary deficiency. Diabetes control was not significantly related to thiamin status.
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Bargren, MaryJean K. "Factors affecting dietary compliance in the adolescent with type 1 diabetes /". View online, 2009. http://repository.eiu.edu/theses/docs/32211131396029.pdf.
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Caramlau, Isabela Oana. "Diabetes and depression". Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3899/.
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Volume 1 of the thesis contains the research component. Paper one is a systematic review of longitudinal studies looking at the association between depression and diabetes complications. Paper two describes a prospective longitudinal study, examining risk factors for postnatal depression in women with gestational diabetes. Paper three is a public dissemination document. Volume 2 of the thesis contains clinical practice reports (CPRs). The reports reflect work conducted during clinical placements, as follows: 1) psychological models CPR (A cognitive-behavioural and psychodynamic formulation in the case of Samuel, a 28-year old man with phobia of falling following an acquired brain injury); 2) service-related CPR (Adherence to initial goal planning meeting clinical standard in an outpatient brain injury rehabilitation service. Factors acting as barriers and facilitators); 3) single-case experimental design CPR (Cognitive behavioural intervention in the case of Alice, a 15-year old White British female with obsessive-compulsive symptoms); 4) case study CPR (The case of Monique, a 55-year old White British female with mild learning disabilities presenting with challenging behaviour); 5) case-study CPR – abstract (The case of Martin, a 67-year old White British male presenting with hypochondriasis). Names and other identifying materials in all the reports were changed in order to protect confidentiality.
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O'Hair, Allison Kelly. "Personalized diabetes management". Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/82725.
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Thesis (Ph. D.)--Massachusetts Institute of Technology, Sloan School of Management, Operations Research Center, 2013.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 105-111).
In this thesis, we present a system to make personalized lifestyle and health decisions for diabetes management, as well as for general health and diet management. In particular, we address the following components of the system: (a) eciently learning preferences through a dynamic questionnaire that accounts for human behavior; (b) modeling blood glucose behavior and updating these models to match individual measurements; and (c) using the learned preferences and blood glucose models to generate an overall diet and exercise plan using mixed-integer robust optimization. In the first part, we propose a method to address (a) above, using integer and robust optimization. Despite the importance of personalization for successful lifestyle modification, current systems for diabetes and dieting do not attempt to use individual preferences to make suggestions. We present a general approach to learning preferences, that includes an efficient and dynamic questionnaire that accounts for response errors, and robust optimization models using risk measures to account for the commonly seen human behavior of loss aversion. We then address part (b) of our system, by first modeling blood glucose behavior as a function of food consumed and exercise performed. We rely on known attributes of dierent foods as well as individual data to build these models. We also show how we use optimization to dynamically update the parameters of the model using new data as it becomes available. In the third part of this thesis, we address (c) by using mixed-integer optimization to nd an optimal meal and exercise plan for the user that minimizes blood glucose levels while maximizing preferences. We then present a robust counterpart to the formulation, that minimizes blood glucose levels subject to uncertainty in the blood glucose models. We have implemented our system as an online application, and conclude by showing a demonstration of the overall program.
by Allison Kelly O'Hair.
Ph.D.
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Pereira, Ana Isabel Avelar. "Diabetes em odontopediatria". Master's thesis, Faculdade de Medicina Dentária da Universidade do Porto, 2009. http://hdl.handle.net/10216/60832.
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Sousa, Sofia Alexandra. "Diabetes Mellitus felina". Master's thesis, Universidade de Évora, 2022. http://hdl.handle.net/10174/30830.
Texto completo da fonteResumo:
O estágio curricular do Mestrado Integrado em Medicina Veterinária da Universidade de Évora realizado durante seis meses no Hospital Veterinário de São Bento, em Lisboa, deu origem ao presente relatório. Este relatório é constituído por duas partes. Na primeira parte fez-se uma breve análise descritiva dos casos clínicos assistidos durante o período de estágio, abordando de forma sumária as patologias mais relevantes para a estagiária. Por sua vez, a segunda parte compreende uma monografia com o tema “Diabetes Mellitus Felina”, onde se realizou uma revisão bibliográfica abordando a fisiologia do pâncreas, a classificação da afeção, a etiologia e patofisiologia, a epidemiologia, a apresentação clínica, o diagnóstico, o tratamento, as complicações associadas, a monitorização e o prognóstico. A Diabetes Mellitus é uma doença endócrina comum no paciente felino que é identificada pela presença de sinais clínicos típicos. Por fim, foi apresentado um caso clínico num gato sendo realizada uma discussão do mesmo; Abstract: Feline Diabetes Mellitus
The internship of the master’s degree in Veterinary medicine from the University of Évora, was held for six months at Hospital Veterinário São Bento, in Lisbon, and resulted in the present report. This report consists of two parts. The first part, was held a brief descriptive analysis of clinical cases assisted during the probationary period, briefly addressing the most relevant pathologies for the intern. In turn, the second part is comprised of the monography with the theme Feline Diabetes Mellitus, where a literature review was carried out addressing physiology of the pancreas, classification of the disease, etiology and pathophysiology, epidemiology, clinical presentation, diagnosis, treatment, associated complications, monitoring and prognosis. Diabetes Mellitus is a common endocrine disease in feline patients that is identified by specific clinical signals. Lastly, a clinical case in a cat was presented and a discussion was carried out.
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Mykhailychenko, K., Світлана Григорівна Золотова, Светлана Григорьевна Золотова e Svitlana Hryhorivna Zolotova. "Streptosotzin diabetes model". Thesis, Sumy State University, 2020. https://essuir.sumdu.edu.ua/handle/123456789/78064.
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Diabetes mellitus (DM) is a widespread disease leading to the development of serious complications, disability and premature death. A mandatory factor in the pathogenesis of type 1 diabetes is absolute insulin deficiency, leading to characteristic metabolic disorders. The fundamental treatment of Type 1 diabetes costs a lot of millions dollars every year for the past 100 years. Medicine spends a huge amount of money for daily insulin injections. Insulin therapy prevents death of patients from hyperglycemic coma, but doesn’t prevent the development of severe chronic complications. That is why, the search of more effective and preferably cardinal ways for antidiabetic treatment is extremely important. Great attention is paid to experiments on animals with experimental diabetes.
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Grankvist, Laban, e Hampus Hörnlund. "Vad är diabetes?" Thesis, Linköpings universitet, Kommunikations- och transportsystem, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-168066.
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Syftet med den här studien var att utforska hur man på ett effektivt sätt kan ta fram en animerad informationsfilm för att ge barn i åldrarna sju till tio år förståelse för diabetes typ 1, och att öka deras handlingsberedskap ifall en diabetesrelaterad krissituation skulle uppstå. Studien inleddes med en förstudie för att ta reda på vad diabetes typ 1 år, om en animerad informationsvideo är ett lämpligt inlärningsformat för målgruppen barn i åldrarna sju till tio, samt vilka designprinciper man bör ha i åtanke vid utformandet av informativa artefakterna som ska vara med under filmen. Arbetet fortgick med en designfas som bestod av utforskning av olika koncept med hjälp av storyboards. De här koncepten utvärderades i olika steg tills ett färdigt manus tog form. Efter att manuset var färdigställt började animeringsfasen. Det här slutade med en stiliserad animerad kortfilm på ungefär fyra minuter som förklarade grunderna kring diabetes och vad som bör göras i en diabetes-relaterad krissituation. Filmen värderades sen av en expert inom utbildning, med hjälp av hans nio-åriga son på grund av att COVID-19 pandemin förhindrade några verkliga möten med målgruppen. Hans åsikter kombinerades sen med vårt teoretiska ramverk för att ta fram studiens analys. Studiens slutsats är att animerade kortfilmer lämpar sig för att informera barn i avsedd åldersgrupp om diabetes typ 1. Ett bra sätt att göra det här på att använda starka kontrasterande färger för att dra fokus till viktiga objekt och använda mediets rörelse för att hålla tittaren underhållen. Det är viktigt att inte tala ner till barn i målgruppen.The purpose of this study was to explore an effective way to create an informative animatedshort film to give children aged seven to ten an understanding of type 1 diabetes, andincrease their readiness in the case of a diabetes-related emergency.The study began with a research study to find out what type 1 diabetes is, if an animatedinformation video is a suitable teaching tool for the target audience of children aged sevento ten, and what design principles one should keep in mind when designing illustrations forchildren.The work proceeded with the design phase, which consisted of exploration of conceptsthrough the use of storyboards. These concepts were evaluated and compared in stages,until a final script was finished. After the script had been finished the animation stageproceeded. This culminated in a stylized animated short film of about four minutes thatexplained the basics of diabetes and what should be done in the case of a diabetes-relatedemergency.The film was then evaluated by an expert in the field of education, with help from his9-year-old son due to the prevailing COVID-19 pandemic preventing any physical meetingswith our target audience. His opinions were then combined with the theoretical framework toform the study’s analysis.The conclusion of this thesis is that the medium of animated short films is suitable forinforming children in the targeted age about diabetes type 1. A good way to do this is tofocus on strong contrasting colours to highlight important objects on screen and focus onusing the strengths of the medium’s movements to keep the viewer entertained. It’simportant not to talk down to the target audience.1
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Thulin, Sofia. "Diabetes i klassen". Thesis, Malmö högskola, Lärarutbildningen (LUT), 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-31734.
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Jag vill genom denna uppsats belysa ett samarbete mellan sjukvårdskulturen ochskolkulturen. I min egen studie har jag gjort intervjuer med personer som har anknytning tilldessa båda kulturer. Om du som barn får diabetes ingår du både i skolkulturen ochsjukvårdskulturen och för att underlätta för patienten/eleven finns ett samarbete. Jag har genommin vft träffat barn som har diabetes och som inspirerat mig till denna uppsats.
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Possfelt, Sofia, e Alfred Bertilsson. "D4Active : Diabetes System". Thesis, Högskolan i Halmstad, Akademin för ekonomi, teknik och naturvetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-40248.
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What is missing today on the Swedish market for diabetic products? Users with diabetes type 1 are today asking for products that will elevate the feeling of freedom and increase the quality of life. Diabetes type 1 is a disease where the pancreas is unable to produce insulin to adjust the level of blood sugar. To keep the value stable is the user in need of external control and insulin injection. Today’s innovations are activity-based products that will offer high technology solutions. The products require the user to adapt, rather than designing the products for the user. The group have enlightened through extensive analysis the occasions a diabetic person perceive itself as exposed. Physical activity was found as the situation to be the hardest to control their values. They lack support from the physical products. The need of user-friendly products that offers greater options for an active lifestyle with a more sustainable suit was noticed. The goal of the project has been to create a prototype that can demonstrate the possibility to simplify the treatment of diabetes through connecting three innovative products. The products will only be felt as one whole system by the user. The product caters the basic need of usability to create greater prerequisites for an easier everyday life. The result of the project consists of a requested prototype of the product developed by the new directive of medical technique, MDR. The system will contribute to reduce excessive units, higher sustainability and greater value for the user. The process of developing have been conjoint with users which creates greater possibility for a higher demand of D4Actives future product.
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Pereira, Ana Isabel Avelar. "Diabetes em odontopediatria". Dissertação, Faculdade de Medicina Dentária da Universidade do Porto, 2009. http://hdl.handle.net/10216/60832.
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Koskinen, J.-P. (Juha-Pekka). "Parondontiitti ja diabetes". Master's thesis, University of Oulu, 2018. http://jultika.oulu.fi/Record/nbnfioulu-201906122523.
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Tiivistelmä. Parodontiitti ja diabetes ovat yleisiä, kroonisia sairauksia, joiden välinen kahdensuuntainen vuorovaikutus on runsaan tutkimuksen kohteena. Tämän tutkielman tarkoituksena on arvioida parodontiitin ja diabeteksen yhteyttä, niiden vuorovaikutusmekanismeja, parodontaalihoidon vaikutuksia diabetekseen sekä diabetespotilaan suun ja hampaiston hoitoa.
Diabetespotilailla on suurempi riski sairastua parodontiittiin ja parodontiittin aiheuttama tulehdustila saattaa heikentää diabetespotilaiden verensokeritasapainoa. Lukuisat epidemiologiset tutkimukset ovat osoittaneet parodontiitin ja diabeteksen välisen yhteyden, vaikka kaksisuuntaisen vuorovaikutusmekanismin tarkka tuntemus on vielä rajallista.
Diabeteksesta johtuva hyperglykemia aiheuttaa muun muassa suuremman reaktiivisten happijohdannaisten syntymisen ja RANK-ligandin sekä AGE-tuotteiden määrän kasvun, joka suorien soluvaurioiden lisäksi johtaa tulehdusta kiihdyttävien sytokiinien pitoisuuden nousuun. Proinflammatoristen ja anti-inflammatoristen sytokiinien tasapainon häiriintyminen johtaa lisäksi muutoksiin immuunipuolustuksen soluissa tulehdusta edistävään suuntaan. Myös tyypin 2 diabetekseen usein liittyvä lihavuus johtaa tulehdustilan kiihtymiseen. Nämä muutokset pahentavat parodontiitin tilannetta.
Parodontiitin aiheuttaman tulehdustilan on todettu huonontavan diabeetikoiden verensokeritasapainoa ja lisäävän diabeteksen komplikaatioiden riskiä. Parodontiumin bakteerien aiheuttama tulehdustila lisää mm. reaktiivisten happijohdannaisten syntymistä. Parodontaalihoitoa pidetäänkin yhtenä keinona verensokeritasapainon parantamiseksi. Useat tutkimukset ovat osoittaneet ei-kirurgisen parodontaalihoidon alentavan diabetesta ja parodontiittia sairastavien HbA1c-pitoisuuksia, tosin myös eriäviä tutkimustuloksia on julkaistu.
Diabetes vaikuttaa monin tavoin suuhun ja hampaistoon, mm. alentuneen syljen erityksen vuoksi, erityisesti sen ollessa huonosti hoidettu. Diabetespotilasta hoitavan hammaslääkärin on huomioitava erityisesti hypoglykemian riski sekä potilaan käyttämä lääkitys. Parodontiitin hoito on erityisen tärkeää diabeetikoilla, ja myös diabeteksen hyvä hoitotasapaino vaikuttaa positiivisesti suunterveyteen.