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Artigos de revistas sobre o assunto "Darwin (N.T)"
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Tabrizi, Sepehr N., Barbara A. Paterson, Christopher K. Fairley, Francis J. Bowden e Suzanne M. Garland. "Comparison of tampon and urine as self-administered methods of specimen collection in the detection of Chlamydia trachomatis , Neisseria gonorrhoeae and Trichomonas vaginalis in women". International Journal of STD & AIDS 9, n.º 6 (1 de junho de 1998): 347–49. http://dx.doi.org/10.1258/0956462981922386.
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1 Department of Microbiology, The Royal Women's Hospital, Victoria, 2 Menzies School of Health Research, Rocklands Drive, Tiwi, 3 Department of Epidemiology and Preventive Medicine, Alfred Hospital, Monash University, Prahran, Victoria and 4 AIDS/STD Unit, Centre for Disease Control, Territory Health Services, Darwin, Australia Summary: Self-administered sampling techniques for the detection of sexually transmitted diseases (STDs) are particularly useful due to their ease of collection and better patient compliance. Urine specimens, and recently tampons, have been described as methods of specimen collection for the detection of some STDs in women. In this study, 660 women had both first-void urine (FVU) and tampon specimens analysed by polymerase chain reaction (PCR) for the detection of Chlamydia trachomatis , Neisseria gonorrhoeae and Trichomonas vaginalis . Overall 6.5%, 10.1% and 17.9% of urine samples were positive whereas 7%, 21.2% and 22% of tampon specimens were positive for C. trachomatis , N. gonorrhoeae and T. vaginalis respectively. Tampon-collected specimens tested by PCR were more sensitive than urine specimens for the detection of N. gonorrhoeae and T. vaginalis ( P 0.001) and equally sensitive for the detection of C. trachomatis ( P =0.45). <
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KANE, R. P. "Comparison of quasi-biennial oscillations of stratospheric winds and atmospheric temperatures at different altitudes". MAUSAM 49, n.º 2 (16 de dezembro de 2021): 223–28. http://dx.doi.org/10.54302/mausam.v49i2.3622.
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During 1959-89, the 12-month running means of 50 hPa zonal winds, the average atmospheric temperatures in the northern and southern hemisphere at four altitude slabs (950 hPa, 850- 300 hPa, 300-100 hPa and 100-50 hPa), Pacific and Atlantic sea surface temperature (SST) and-30hPa temperatures at North Pole and average for (10°-90° N), all showed quasi-biennial oscillations (QBO). However, whereas the wind QBO had an average spacing of 29 months, only temperatures at 300-100 hPa and Atlantic SST had similar average spacing. Other temperatures as also SO index (represented by Tahiti minus Darwin atmospheric pressure) had larger average spacing. Spectral analysis showed that whereas wind QBO had only one prominent peak at T=2.33 years, other parameters had weak QBOs near T=2.5-2.6 years except Pacific SST and 30 hPa North Pole temperature which had small peaks near T=2.3 years. All the temperatures had prominent peaks in the 3-6 year region which matched with similar peaks in the SO index. There is some indication that stratospheric wind QBO had some relation with parameters at all altitudes in tropics and with North Pole, while ENSO had considerable influence at other latitudes/altitudes.
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Zhang, Mengjuan, Yuefeng Cai, Nanjing Ji, Benny Kwok Kan Chan e Xin Shen. "The Mitochondrial Genome of the Globally Invasive Barnacle Megabalanus coccopoma Darwin 1854 (Crustacea: Balanomorpha): Rearrangement and Phylogenetic Consideration within Balanomorpha". Diversity 15, n.º 1 (14 de janeiro de 2023): 117. http://dx.doi.org/10.3390/d15010117.
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Megabalanus coccopoma (Darwin, 1854) is a globally invasive species in Balanomorpha (Crustacea). This species is a model organism for studying marine pollution and ecology. However, its mitogenome remains unknown. The mitogenome sequencing of M. coccopoma is completed in the present study. It has a 15,098 bp in length, including 13 protein-coding genes (PCGs), 2 ribosomal RNAs (rRNAs), 22 transfer RNAs (tRNAs), along with a putative regulatory area. A substantial A+T bias was observed in the genome composition (68.2%), along with a negative AT (0.82) and GC (−0.136) skew. Compared to the gene sequence of the ground model of pan-crustacea, 13 gene clusters (or genes), such as 10 tRNAs and 3 PCGs, were observed in a different order. This was in line with the previously observed large-scale gene rearrangements of Balanomorpha. Among the 37 genes, the gene cluster (M-nad2-W-cox1-L2-cox2-D-atp8-atp6-cox3-G- nad3-R-N-A-E-S1) Balanomorpha was conserved. Furthermore, phylogeny analysis indicated that the existing Balanomorpha species family was divided into nine rearrangement patterns, supporting the polyphyly of Balanoidea.
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Kwok, Darwin W., Michael Y. Zhang, Cliff Wang, Nicholas Stevers, Tyler Borrman, Zheng Pan, Benjamin Yuen et al. "Abstract 895: Tumor-wide neoantigen-specific T-cells infiltrating mutant IDH1 low-grade gliomas and persisting in peripheral blood allow for personalized TCR-based immunotherapies". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 895. http://dx.doi.org/10.1158/1538-7445.am2023-895.
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Abstract BACKGROUND: The low mutational burden and immunologically “cold” microenvironment of mutant IDH1 low-grade gliomas (LGG) are considerable challenges facing immunotherapy against these tumor types. However, we hypothesize that LGG-targeting T-cells may exist at low frequency and with limited regional infiltration within the tumor. Multi-region tumor sampling coupled with high-throughput T-cell receptor (TCR) profiling across the LGG landscape detected neoantigen-specific T-cells that persisted in peripheral blood. TCR-engineered T-cells transduced with these TCRs demonstrated neoantigen-specific immunogenicity. METHODS: Maximal-anatomical sampling of at least 10 distinct tumor regions were collected at the initial resection for three WHO Grade II diffuse astrocytoma patients for exome-based prediction of clonally and subclonally expressed neoantigens, RNAseq analysis of regional immune cell composition, and TCR beta deep sequencing. We used these predictions to generate a barcoded library of patient-specific peptide-HLA multimers loaded with predicted neoepitopes. With this library, neoantigen-specific CD8+ T-cells were captured and isolated from patient peripheral blood. Single cell TCR sequencing allowed us to identify the neoantigen-reactive TCR clonotypes which were transduced subsequently into Jurkat76 cell lines for functional validation. RESULTS: We screened patient-derived peripheral blood drawn two years after initial resection in 3 mutant IDH1 LGG patients and detected a total of 20 TCR clonotypes recognizing neoepitopes derived from truncal, tumor-wide mutations in CNTNAP1 (n=8), TP53 (n=3), and MRPL46 (n=2) as well as subclonal mutations in PRMT5 (n=1) and ZDHHC5 (n=6). Multi-sampling RNAseq analysis indicated varying degrees of interpatient and intratumoral immune infiltration as well as distally located populations of neoantigen-reactive T-cells within the tumor, suggesting widespread migration of neoantigen-specific T-cells across the glioma landscape. We proceeded with TCR functional analysis for one patient (P375) with 5 detected TCR clonotypes recognizing neoantigens derived from mutations in PRMT5, MRPL46, and TP53. Jurkat76 cells transduced with the mutant-PRMT5-specific TCR demonstrated a neoantigen-specific immune response when co-cultured with mutant-PRMT5 pulsed-antigen presenting cells expressing HLA-A*0201 (T2 cells). CONCLUSION: Our study demonstrates the existence and persistence of neoantigen-targeting T-cells within the blood and tumor of mutant IDH1 LGG patients. We identified a TCR clonotype that successfully recognizes and induces an immune response against mutant-PRMT5. These findings suggest a feasible methodology to develop personalized T-cell-based immunotherapies for patients with mutant IDH1 LGGs. Citation Format: Darwin W. Kwok, Michael Y. Zhang, Cliff Wang, Nicholas Stevers, Tyler Borrman, Zheng Pan, Benjamin Yuen, Songming Peng, Diana Nguyen, Michael Martin, Chibo Hong, Stephanie Hilz, Joanna Phillips, Anny Shai, Nancy Ann Oberheim Bush, Shawn Hervey-Jumper, Michael McDermott, Stefanie Mandl, Hideho Okada, Joseph Costello. Tumor-wide neoantigen-specific T-cells infiltrating mutant IDH1 low-grade gliomas and persisting in peripheral blood allow for personalized TCR-based immunotherapies [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 895.
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Kwok, Darwin W., Takahide Nejo, Nicholas Stevers, Lee H. Chen, Kaori Okada, Chibo Hong, Gary K. Chan et al. "Abstract 3152: Targetable public neoantigens are generated by tumor-wide cancer-specific splicing events in gliomas". Cancer Research 83, n.º 7_Supplement (4 de abril de 2023): 3152. http://dx.doi.org/10.1158/1538-7445.am2023-3152.
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Abstract BACKGROUND: The efficacy of immunotherapy in gliomas is limited by tumor heterogeneity and low mutational burden. Recent studies revealed increased alternative splicing (AS) in various cancer types that potentially translate into targetable neoantigens. We developed a novel comprehensive in silico pipeline for detecting tumor-specific AS events (neojunctions), and successfully identified tumor-wide, public, alternatively spliced neoantigens (ASNs) that elicited CD8+ T-cell-mediated immune responses. METHODS: Our computational pipeline first identified recurring splice junctions in high purity TCGA LGG/GBM bulk RNA-seq samples (n=429, PSR > 10%) and not in GTEx normal tissue bulk RNA-seq data (n=9166, PSR < 1%). We subsequently employed two independent algorithms to predict the peptide processing likelihood and the HLA-binding affinity of ASN candidates before validating neojunction and ASN expression in RNA-seq data from patient-derived glioma cell lines (n=68) and spatially-mapped glioma samples (n=535), and in the Clinical Proteomic Tumor Analysis Consortium (CPTAC) GBM mass spectrometry data (n=99). In vitro sensitization of healthy donor-derived CD8+ T-cells against our top ASN candidates followed by 10x VDJ scRNA-seq was performed to identify ASN-specific TCR sequences. We transduced these TCRs into Jurkat76s and co-cultured them with ASN-pulsed T2 cells and ASN and HLA-expressing COS7 cells to determine whether the TCR recognized the presented HLA:ASN. RESULTS: Our analysis identified 249 putative neojunctions that translated into 222 cancer-specific peptides sequences. Iterating across these peptides yielded 17,562 glioma-specific n-mer sequences between 8 to 11 amino acids in length. Both prediction algorithms concurrently identified 636 n-mers likely to be presented by demographically common HLA haplotypes. Through transcriptomic and proteomic validation with patient-derived samples and cell lines, we identified 8 ASNs that were tumor-wide, 4 of which were predicted to be HLA*A0201-presented. In vitro sensitization of healthy-donor derived CD8+ T-cells against these 4 ASNs resulted in an expansion of reactive CD8+ T-cells against ASNs derived from neojunctions within S100A6, RPL22, and GNAS. Subsequent 10x VDJ scRNA-seq on the expanded CD8+ population identified mutRPL22-reactive TCR clonotypes with neoantigen-mediated increases in IFNG and GZMB signatures. When transduced and expressed in Jurkat76 cells, one particular TCR clonotype demonstrated recognition and immunogenic activation against mutRPL22-pulsed T2 cells and COS7 cells endogenously expressing both HLA*A0201 and mutRPL22. CONCLUSION: Our unique integrative pipeline detected novel tumor-wide splice-derived neoantigen candidates, and ASN-reactive TCRs identified through our pipeline offer a new avenue for TCR-based therapies across cancer types. Citation Format: Darwin W. Kwok, Takahide Nejo, Nicholas Stevers, Lee H. Chen, Kaori Okada, Chibo Hong, Gary K. Chan, Akane Yamamichi, Aidan Du, Maggie Colton, James Woo, Joseph Costello, Hideho Okada. Targetable public neoantigens are generated by tumor-wide cancer-specific splicing events in gliomas [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 3152.
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Kwok, Darwin, Nicholas O. Stevers, Takahide Nejo, Lee H. Chen, Inaki Etxeberria, Jangham Jung, Kaori Okada et al. "Abstract 3907: Novel public and tumor-wide neoantigens arising from clonal aberrant splicing events drive tumor-specific T-cell responses across diverse cancer types". Cancer Research 84, n.º 6_Supplement (22 de março de 2024): 3907. http://dx.doi.org/10.1158/1538-7445.am2024-3907.
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Abstract BACKGROUND: Immunotherapy in gliomas is limited by intratumor heterogeneity (ITH) and low mutational burden. We developed a novel comprehensive in silico pipeline for detecting tumor-specific splicing events (neojunctions), and across multiple cancer types, we successfully identified a new class of tumor-wide, public, alternatively spliced neoantigens (ASNs) that elicit CD8+ T-cell-mediated immune responses. METHODS: Our pipeline identified recurring public neojunctions expressed in TCGA RNA-seq (positive sample rate (PSR) > 10%) and not in GTEx normal tissue RNA-seq data (PSR < 1%) across ten cancer types. To characterize tumor-wide neojunctions, we utilized available multi-site RNA sequencing across diverse cancer types. With gliomas, our in-house dataset comprised of 56 patients with approximately 10 maximally-distanced intratumoral biopsy sites per patient (n=535). Tumor-wide public neojunction expression was subsequently validated in RNA-sequencing and mass spectrometry (MS) data from patient-derived cell lines (n=68) and samples (n=447). Two independent algorithms then predicted peptide processing likelihood and HLA-binding affinity of ASN candidates. TCRs identified by in vitro sensitization (IVS) of donor-derived CD8+ T-cells followed by 10x VDJ scRNA-seq, were transduced into CD8+ T-cells and co-cultured with tumor cells to evaluate TCR functionality and cytotoxicity. RESULTS: Pan-cancer analysis identified large subsets of neojunctions that were interpatiently and intratumorally conserved. Our glioma-specific analysis identified 789 public neojunctions, and 8 ASNs were validated in transcriptomic and proteomic glioma data and predicted to be presented by HLA-A*02:01 with high confidence. IVS and subsequent 10x VDJ scRNA-seq on expanded PBMC-derived CD8+ populations cultured against ASN-pulsed dendritic cells identified TCR clonotypes reactive against neojunctions in RPL22 (n=7) and GNAS (n=1), the latter being highly intratumorally-conserved (detected in > 90% of spatially-mapped biopsies in 17/56 patients (26.78%)). TCR-transduced T-cells demonstrated recognition and immunogenic activation against endogenously processed and presented neoantigens in both pan-cancer cell lines and transfected COS7 cells and cytotoxicity against glioma cell lines. Pan-cancer analysis revealed the detection of both neojunctions in various tumor types beyond gliomas, with the GNAS neojunction notably found tumor-wide in mesothelioma, prostate cancer, and liver hepatocellular carcinoma spatial data. CONCLUSION: Our unique integrative pipeline identified a novel class public tumor-wide splice-derived neoantigen candidates and ASN-specific TCRs, offering a promising off-the-shelf immunotherapy approach for diverse cancer types and tackling the critical challenge of ITH in immunotherapy resistance. Citation Format: Darwin Kwok, Nicholas O. Stevers, Takahide Nejo, Lee H. Chen, Inaki Etxeberria, Jangham Jung, Kaori Okada, Maggie Colton Cove, Senthilnath Lakshmanachetty, Marco Gallus, Abhilash Barpanda, Chibo Hong, Gary KL Chan, Samuel H. Wu, Emilio Ramos, Akane Yamamichi, Jerry YZ Liu, Payal Watchmaker, Hirokazu Ogino, Atsuro Saijo, Aidan Du, Nadia Grishanina, James Woo, Aaron Diaz, Susan M. Chang, Joanna J. Phillips, Arun P. Wiita, Christopher A. Klebanoff, Joseph F. Costello, Hideho Okada. Novel public and tumor-wide neoantigens arising from clonal aberrant splicing events drive tumor-specific T-cell responses across diverse cancer types [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 3907.
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Vinogradova, O. A., e A. V. Ugleva (Yastrebtseva). "The Birth of the Idea of Perfectibility: From the Enlightenment to Transhumanism". Russian Journal of Philosophical Sciences 62, n.º 4 (6 de julho de 2019): 113–31. http://dx.doi.org/10.30727/0235-1188-2019-62-4-113-131.
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Starting from the Age of Enlightenment, a person’s ability of self-improvement, or perfectibility, is usually seen as a fundamental human feature. However, this term, introduced into the philosophical vocabulary by J.-J. Rousseau, gradually acquired additional meaning – largely due to the works of N. de Condorcet, T. Malthus and C. Darwin. Owing to perfectibility, human beings are not only able to work on themselves: by improving their abilities, they are also able to change their environment (both social and natural) and create favorable conditions for their existence. It is no coincidence that perfectibility became the key concept of the idea of social progress proposed by French thinkers in the Age of Enlightenment, despite the fact that later it was criticized, above all, by English authors, who justified its organic and biological nature and gave a different evolutionary interpretation to this concept, without excluding perfectibility from the philosophical vocabulary. In this article, we address the opposition and mutual counterarguments of these two positions. Beyond that, we draw a parallel with some of the ideas of S. Kapitsa, who proved to be not only a critic of Malthusianism but also a direct disciple of Condorcet. In the modern age, the ideas of human self-improvement caused the development of transhumanist movement. Condorcet is more relevant than ever, and today his theory of the progress of the human mind, which influenced the genesis of modern historical science, needs a re-thinking in the newest perspective of improving the mental and physical human nature with the help of modern technologies.
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Lee, Joan. "Reviewer Acknowledgements for Sustainable Agriculture Research, Vol. 9, No. 2". Sustainable Agriculture Research 9, n.º 2 (26 de abril de 2020): 129. http://dx.doi.org/10.5539/sar.v9n2p129.
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Sustainable Agriculture Research wishes to acknowledge the following individuals for their assistance with peer review of manuscripts for this issue. Their help and contributions in maintaining the quality of the journal are greatly appreciated.
Sustainable Agriculture Research is recruiting reviewers for the journal. If you are interested in becoming a reviewer, we welcome you to join us. Please contact us for the application form at: sar@ccsenet.org
Reviewers for Volume 9, Number 2
Adel Khashaveh, Islamic Azad University, Iran
Darwin Pangaribuan, Lampung University, Indonesia
Dietrich Darr, Hochschule Rhein-Waal, Germany
Entessar Mohammad Al JBawi, General Commission for Scientific Agricultural Research, Syria
Francesco Sunseri, Università Mediterranea di Reggio Calabria, Italy
Gema Parra, Universidad de Jaén, Spain
Giuseppina Migliore, University of Palermo, Italy
Gunnar Bengtsson, Sweden
Inder Pal Singh, Guru Angad Dev Veterinary and Animal Science University (GADVASU), India
Isaac Danso, Council for Scientific and Industrial Research-Oil Palm Research Institute, Ghana
Kassim Adekunle Akanni, Olabisi Onabanjo University, Nigeria
Katarzyna Panasiewicz, Poznan University of Life Sciences, Poland
Manuel Teles Oliveira, University Tras os Montes Alto Douro (UTAD), Portugal
Maren Langhof, Julius Kühn-Institut, Germany
Murtazain Raza, Subsidiary of Habib Bank AG Zurich, Pakistan
Nehemie T. Donfagsiteli, Institute of Medical Research and Medicinal Plants Studies, Cameroon
Nicusor-Flavius Sima, University of Agricultural Studies and Veterinary Medicine Cluj-Napoca, Romania
Sait Engindeniz, Ege University Faculty of Agriculture, Turkey
Stefano Marino, University of Molise, Italy
Subhash Chand, Central Agricultural Research Institute CARI Port Blair, India
Suheb Mohammed, University of Virginia, United States
Tenaw Workayehu, Hawassa Research Center, Southern Agricultural Research Institute, Ethiopia
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GIBSON, GARY A. P., CHARLES DEWHURST e SIMON MAKAI. "Nomenclatural changes in Anastatus Motschulsky and the description of Anastatus eurycanthae Gibson n. sp. (Eupelmidae: Eupelminae), an egg parasitoid of Eurycantha calcarata Lucas (Phasmida: Phasmatidae) from Papua New Guinea". Zootaxa 3419, n.º 1 (13 de agosto de 2012): 53. http://dx.doi.org/10.11646/zootaxa.3419.1.2.
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Anastatus eurycanthae Gibson n. sp. (Eupelmidae: Eupelminae) is newly described as an egg parasitoid of Eurycanthacalcarata Lucas (Phasmida: Phasmatidae), an important pest of oil palm in Papua New Guinea. Both sexes are describedand illustrated by macrophotography and scanning electron microscopy. Basic biological data are provided on the parasi-toid. Six species are transferred from A. (Anastatus) Motschulsky to other genera, namely Eupelmus tennysoni Girault(1921) revived comb., Eupelmus (Eupelmus) darwini (Girault 1915) n. comb., Reikosiella (Hirticauda) pasteuri (Girault1915) n. comb., R. (Hirticauda) tricolor (Girault 1915) n. comb., Tineobius (Tineobius) adamsi (Yoshimoto & Ishii 1965) n. comb., and T. (Tineobius) crassipes (Yoshimoto & Ishii 1965) n. comb.
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Gorochov, A. V., M. K. Tan e Ch Ya Lee. "Taxonomic notes on the cricket subfamilies Nemobiinae and Trigonidiinae (Orthoptera: Gryllidae) from islands and coasts of the Pacific and Indian Oceans". Zoosystematica Rossica 27, n.º 2 (17 de dezembro de 2018): 290–321. http://dx.doi.org/10.31610/zsr/2018.27.2.290.
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Several taxa of Nemobiinae and Trigonidiinae from some islands and coasts of Pacific Ocean and Andaman Sea (Indian Ocean) are considered. The tribes Marinemobiini Gorochov, 1985 and Burcini Gorochov, 1986 are briefly redescribed, and the tribes Nemobiini Saussure, 1877 and Pteronemobiini Vickery, 1973 are also discussed. Some genera of Marinemobiini (Marinemobius Gorochov, 1985, Apteronemobius Chopard, 1929 and Parapteronemobius Furukawa, 1970) as well as type species of Apteronemobius (A. longipes Chopard, 1929) are redescribed; Marinemobius and Parapteronemobius are restored from synonyms of Apteronemobius and Caconemobius Kirby, 1906, respectively (with the suggestion of three new combinations for the specific names); Eumarinemobius sundaicus gen. et sp. nov. is described from the Malay Peninsula and nearest islands, and former Apteronemobius darwini Otte et Alexander, 1983 is supposedly included in this genus (as E. darwini comb. nov.); Parapteronemobius sazanami kunashir subsp. nov. is described from the Kuril Islands. The tribe Burcini is restored from synonyms of Thetellini Otte et Alexander, 1983, and its following taxa are redescribed or described as new for the science: Burcus Gorochov, 1986 which is also restored from synonyms of Thetella Otte et Alexander, 1983; B. trilobulatus sp. nov. from Thailand; B. t. bunaken subsp. nov. from Indonesia; Paraburcus gen. nov. for Thetella elegans Kobayashi, 1983 (= P. elegans comb. nov.); Neoburcus tarutao gen. et sp. nov. from Thailand. The unavailable tribal name Thetellini is considered as a possible synonym of Nemobiini, and its type genus and species (Thetella and Th. oonoomba Otte et Alexander, 1983 from Australia) as well as some other genera from Pacific islands must be preliminary placed in this tribe, but the genus Caledonina Desutter-Grandcolas, 2016 from New Caledonia probably belongs to Pteronemobiini. Two generic names of Hawaiian Trigonidiinae (Zudella Gorochov, 1988 and Nudilla Gorochov, 1988) are restored from subgenera and synonyms of Trigonidium Rambur, 1838, respectively: the genus Zudella includes numerous Hawaiian species erroneously placed in Trigonidium (they are listed here); the genus Nudilla is here synonymised with Laupala Otte, 1994, syn. nov., and the neotype for Nudilla type species (Trigonidium pacificum Scudder, 1869) is here designated, as well as a new replacement specific name (N. danieli nom. nov.) is here given for the secondary homonym Laupala pacifica Otte, 1994. Also 169 new combinations for specific names in the two latter genera are proposed; T. kolekole Otte, 1994, syn. nov. and L. cerasina Otte, 1994, syn. nov. are synonymised with Z. hawaiiensis Gorochov, 1986 and N. pacifica (Scudder, 1869), respectively.
Livros sobre o assunto "Darwin (N.T)"
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Jesus History And Mt Darwin An Academic Excursion. Lutterworth Press, 2008.
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Richard, Owen. Zoology of the Voyage of H. M. S. Beagle, under the Command of Captain Fitzroy, R. N. , During the Years 1832 To 1836: Birds, by J. Gould [with Notice of Their Habits and Ranges by C. Darwin, and with an Anatomical Appendix by T. C. Eyton. 1841. 4 P. Creative Media Partners, LLC, 2023.
Encontre o texto completo da fonteCapítulos de livros sobre o assunto "Darwin (N.T)"
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"W. Dahr, in Recent Advance in Blood Group Biohchemistrv, V. Vengelen-Tyler and W.J. Judd, eds. American Association of Blood Banks, Arlington, VA (1986) pp. 23-65. 32. J-P. Cartron, in Monoclonal antibodies against human red blood cell and related antigens. P. Rouger and C. Salmon, eds. Arnette, Paris (1987) pp. 69-97. 33. D.J. Anstee, Vox Sang., 58, 1-20 (1990). 34. P. Tippett, in Blood Group Systems: Rh. V. Vengelen-Tyler and S. Pierce, eds. American Association of Blood Banks, Arlington, VA (1987) pp. 25-53 35. C. Lomas, J. Poole, N. Salaru, M. Redman, K. Kirkley, M. Moulds, J. McCreary, G.S. Nicholson, H. Hustinx and C. Green, Vox Sang., 59, 39-43 (1990). 36. J. Poole, H. Hustinx, H. Gerber, C. Lomas, Y.W. Liew, and P. Tippett, Vox Sang., 59, 44-47 (1990). 37. M. Bizot, C. Lomas, F. Rubio and P. Tippett, Transfusion, 28, 342-345 (1988). 38. N.A. Ellis, T-Z. Ye, S. Patton, J. German, P.N. Goodfellow and P. Weller, Nature Genet., 6, 394-400 (1994). 39. C. Gelin, F. Aubrit, A. Phalipon, B. Raynal, S. Cole, M. Kaczorek and A. Bernard, EMBO J., 8, 3253-3259 (1989). 40. M.N. Dworzak, G. Fritsch, P. Buchinger, C. Fleischer, D. Printz, A. Zellner, A. Schollhammer, G. Steiner, P.F. Ambros and H. Gadner, Blood, 83, 415-425 (1994). 41. R. Levy, J. Dilley, R.l. Fox and R. Warnke, Proc. Natl. Acad. Sci. USA, 76, 6552-6556 (1979). 42. G.S. Banting, B. Pym, S.M. Darling and P.N. Goodfellow, Mol Immunol., 26, 181-188 (1989). 43. P. Goodfellow, G. Banting, D. Sheer, H.H. Ropers, A. Caine, M.A. Ferguson-Smith, S. Povey and R. Voss, Nature, 302. 346-349 (1983). 44. S.M. Darling, G.S. Banting, B. Pym, J. Wolfe and P.N. Goodfellow, Proc. Natl. Acad. Sci. USA, 83, 135-139 (1986). 45. P.N. Goodfellow and P. Tippett, Nature, 289. 404-405 (1981). 46. P. Tippett, M-A. Shaw, C.A. Green and G.L. Daniels, Ann. Hum. Genet., 50, 339-347 (1986). 47. G.S. Banting, B. Pym and P.N. Goodfellow, EMBO J., 4, 1967-1972 (1985). 48. F. Latron, D. Blanchard and J-P. Cartron, Biochem. J., 247, 757-764 (1987). 49. R. Herron and G.A. Smith, Biochem. J., 262. 369-371 (1989). 50. A.C. Petty and P. Tippett Submitted." In Transfusion Immunology and Medicine, 200–205. CRC Press, 1995. http://dx.doi.org/10.1201/9781482273441-18.
Texto completo da fonteTrabalhos de conferências sobre o assunto "Darwin (N.T)"
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Terenzi, Benedetta, Valeria Menchetelli, Giacomo Pagnotta e Ludovica Avallone. "Connection between AI and product design - Potentials and critical issues in the text-to-image software-assisted design experience". In Intelligent Human Systems Integration (IHSI 2024) Integrating People and Intelligent Systems. AHFE International, 2024. http://dx.doi.org/10.54941/ahfe1004511.
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Driven by the demand for innovation, design is constantly evolving and is increasingly focused on integrating new technologies into design processes. Technological innovations have proven to be of fundamental importance, both in speeding up and improving production processes and managing and enriching the ideational process.We are now surrounded by software in which the participation of artificial intelligence is constant, but although it has become pervasive, we often do not even notice its presence. In the field of product design, several software exploiting artificial intelligence have been diffused to provide us with virtual products at the two-dimensional level. These software are capable of transforming the ideational stages of a project, as they generate original idea proposals in a matter of minutes. One of the most popular software is Midjourney, which is based on the key text-to-image concept, and can create images from prompts, and descriptive keywords provided by the designer. There are also interesting examples in this regard. Think of the work done by Filippo Nassetti, a British architect and designer, who came up with a series of sunglasses and eyeglasses by going through Midjourney, to obtain zoomorphic-inspired products that recall the textures of biological and mineral microstructures. The surreal collection of biomorphically shaped glasses is an example of the exploration of the creative potential of Midjourney software.Another interesting project is the one tackled by the Oio company for the Spawns spoon collection, in collaboration with Giosanpietro Jewelry. According to Simone Rebaudengo, director and co-founder together with Matteo Loglio of the Oio company, the products in the Spawns collection derive from an ongoing dialogue between different skills that has led to the collaboration between man and algorithm, resulting in an expansion of the handmade, merging the ancient world of craftsmanship with that of advanced technology, defining what they call 'craft intelligence.The paper aims to explore the relationships, potentials and limitations of integrating artificial intelligence into the design process through a design experience that tests the innovative potential of text-to-image software in product ideation and reflects on the redefinition of the designer's role in this rapidly and continuous changing scenario.The case study presented therefore experiments with a design process in which the ideation phase is supported by AI, particularly by text-to-image software, which allows textual descriptions to be translated into visual representations, generating highly detailed images and offering new creative possibilities. The work addressed outlines perspectives and critical issues, which deserve further investigation. On the one hand, one potential that is being outlined is the possibility of visualizing even complex ideas by entrusting the imaginative component to the software, having a multiplicity of alternatives and expanding the ideational range with novel solutions from which to make more informed design choices. Text-to-image software also simulates effective virtual prototyping, allowing a concept to be prefigured and visualized in a three-dimensional context before committing to physical production.On the other hand, text-to-image software has some significant limitations, for example in the poor correspondence of generated images with design intentions and the designer's need to acquire technical skills to effectively use text-to-image software, going on to delineate the possibility of a figure such as that of the prompt designer.Therefore, the presented project aims to contribute to the contemporary debate on the integration of AI into design processes with the collaboration of text-to-image software as another avenue for innovation in product design. The scenario sketched out defines an area in which the role of the designer and human creativities proves irreplaceable, leaving one to understand how more and more a process of understanding and collaboration with AI technologies is needed, and how the skills required of future designers are going to vary and expand.Nozaki, N., Konno, E., Sato, M., Sakairi, M., Shibuya, T., Kanazawa, Y., & Georgescu, S., 2017, Application of artificial intelligence technology in product design. Fujitsu Sci. Tech. J, 53(4), 43-51.F. Morace, Design più umano. Quello che l’intelligenza artificiale non potrà mai darci. Egea, 2018S. Quintarelli, Intelligenza artificiale: cos'è davvero, come funziona, che effetti avrà. Bollati Boringhieri, Torino, 2020G. E. Valori, Intelligenza artificiale tra mito e realtà. Motore di sviluppo o pericolo imminente? Rubbettino, 2021L. Keeheon, A Systematic Review on Social Sustainability of Artificial Intelligence in Product Design. Sustainability 2021, 13(5), 2668; https://doi.org/10.3390/su13052668M. Mitchell, L'intelligenza artificiale: una guida per esseri umani pensanti. Einaudi, 2022