Teses / dissertações sobre o tema "Cell-Embryon"
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Veja os 39 melhores trabalhos (teses / dissertações) para estudos sobre o assunto "Cell-Embryon".
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Savagner, Pierre. "Etude des mécanismes invasifs de colonisation de l'ébauche thymique par des précurseurs hématopoïétiques chez l'embryon d'oiseau". Paris 6, 1986. http://www.theses.fr/1986PA066530.
Texto completo da fonteShajahan, Shireen. "Z-DNA drives Zscan4-dependent chromatin reorganization to induce and safeguard totipotent stem cell identity". Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS221.pdf.
Texto completo da fonteMammalian development is characterized by a sequence of cell fate decisionsalong an irreversible pathway of restricted developmental potential and increasingcell specialization. With progressing development, a gradual restriction inpotency is accompanied by significant transcriptome modulation and drasticchromatin reprogramming. Totipotent 2-cell (2C) embryos are defined by aunique transcriptional signature and a relaxed chromatin organization (globalhypomethylation, poor chromatin organization and increased chromatinaccessibility). However, how 2C embryos safeguard their strict cell identity in arelaxed chromatin conformation remains poorly understood.The spontaneous conversion of mouse embryonic stem cells (mESCs) to a 2C-like state, called 2C like cells (2CLCs), provides a convenient in vitro modelsystem to study totipotent-like characteristics as they share several features with2C embryos. To investigate genome-wide chromatin interactions, chromosomeconformation capture experiments (Hi-C) were conducted in both mESCs and2CLCs. While the global chromosome architecture remained stable between thetwo cell populations, we identified new large interacting regions specific to2CLCs, located towards one end of numerous chromosomes. The formation ofthese chromatin interactions depends on Zscan4, a transcription factor expressedspecifically at the 2C stage. Intriguingly, Zscan4 binds to motifs predisposed toadopt a Z-DNA conformation, characterized by a left-handed double helix. Wedetected the presence of Z-DNA in 2CLCs, and inducing it significantly increasedthe proportion of 2CLCs displaying chromatin conformation akin to spontaneous2CLCs. Mechanistically, we propose that Z-DNA formation plays a role inaltering DNA replication timing, a process known to promote cell transitions.In summary, we propose a novel role for Zscan4 in forming 3D genomeinteraction, a process that may be critical in establishing and maintainingtotipotency
Geiselmann, Anna Maria. "The PI3K/AKT pathway regulates cell fate identities during early mouse development". Electronic Thesis or Diss., Sorbonne université, 2022. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2022SORUS138.pdf.
Texto completo da fonteThe early mouse embryo is a unique paradigm for regulative development which requires a fine-tuned balance between plasticity and commitment. In just a few days, the fertilized egg forms a multicellular embryo which is able to attach to and develop intricate connections with the mother's uterine tissue. Initially equivalent, early embryonic cells become restricted in their developmental potential and commit to a specific cell identity while keeping short windows of responsiveness to react to external cues or developmental perturbations. Shortly before implantation, the inner cell mass (ICM) of early blastocysts differentiates into the epiblast (Epi), that will give rise to the fetus, and the primitive endoderm (PrE), at the origin of extraembryonic tissues. Previous studies have established a regulatory network, involving the transcription factors (TFs) NANOG and GATA6 and the FGF/ERK signaling, which controls many aspects of this differentiation process. However, several questions remain about the underlying mechanisms controlling the generation of the first embryonic lineages. The objective of this thesis was to study the role of PI3K/AKT signaling during blastocyst development when first Epi, then PrE cells arise from the uncommitted pool of ICM cells. My work demonstrates that PI3K/AKT is constitutively active during preimplantation development and that variations of signaling activities occur during mid to late blastocyst stages. By modulating pathway activity, I could demonstrate that PI3K/AKT activity is a premise for Epi formation as the Epi-specific TFs NANOG and SOX2 are dramatically reduced and endodermal SOX17 is activated in the absence of PI3K/AKT. I further provide evidence that the regulation of TF patterning in the ICM is, at least in part, mediated by the PI3K/AKT downstream target GSK3. Single cell RNA sequencing (scRNAseq) revealed that PI3K/AKT inhibition induced marginal alterations in the inner cell transcriptome, indicating that PI3K/AKT regulates TFs levels through post-transcriptional mechanisms. Surprisingly, I observed upregulation of SOX17 when PI3K/AKT is inhibited in Gata6 mutant embryos which suggests that initiation of PrE fate requires the release of PI3K/AKT inhibition. In conclusion, this PhD project illustrates that PI3K/AKT, a pathway often associated with controlling survival, proliferation and metabolism, acts also as a mediator of cell fate during a specific and limited period of early mouse development. We propose that PI3K/AKT guards the pluripotency of forming Epi progenitors by maintaining the expression of key Epi markers while simultaneously preventing differentiation towards PrE fate. Thus, my work gives novel and important insights into the regulation of the Epi master TF NANOG in early embryos and identifies signals other than FGF/ERK signaling that participate in lineage decisions independently of the latter
Fremont, Patrick. "Differenciation en culture in vitro de myoblastes d'ebauches musculaires lentes et rapides de l'embryon d'oiseau : influence de l'innervation et de l'activite mecanique". Nantes, 1987. http://www.theses.fr/1987NANT2028.
Texto completo da fonteRosfelter, Anne. "Le positionnement du fuseau mitotique chez le zygote d'ascidie et son rôle dans la répartition des organelles". Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS063.
Texto completo da fonteAfter oocyte fertilization, a microtubule aster forms around the male DNA. The sperm aster brings the female pro-nucleus to the male pro-nucleus so they can fuse, but it also moves the fused nuclei to the cell center to ensure an equitable cell division. Numerous studies performed in vitro, by modeling or experimentally in species such as C. elegans, P. lividus, and M. musculus, addressed the aster and spindle centration mechanisms. Three main mechanisms emerged; pushing, cortical pulling, and cytoplasmic pulling. By studying aster centration in the zygote of the ascidian P. mammillata, I discovered a system that combines these three mechanisms based on the cell cycle stages. In meiosis, the aster uses the polymerization of its microtubules to push against the actin cortex and move away from it (pushing). Once in interphase, the aster returns to the cortex by a pull exerted by the membrane on the microtubules (cortical pulling). At mitosis entry, cortical pulling stops, and releases the mitotic spindle's asters. In consequence, the asters give in to the forces exerted by the transport of organelles to the aster center (cytoplasmic pulling), that appeared constant during the cell cycle. Cytoplasmic pulling hence participate in centering the spindle While the aster forms and moves, the intracellular compartments reorganize. To understand how intracellular organization can be disrupted by aster formation, I studied the case of yolk. The yolk, in the form of vesicles (called granules or platelets), is initially abundant and homogeneous in the unfertilized oocyte. However, as soon as the aster appears, its distribution changes and the yolk platelets are excluded from the region containing the aster. This exclusion generated by the aster formation in the zygote is maintained during development. I observed that yolk exclusion is mainly due to the accumulation at the aster of other organelles such as the endoplasmic reticulum. The transport function of the aster microtubules is therefore sufficient to completely reorganize the cell by excluding some organelles and accumulating others. The movements of the aster and the spindle, their regulation by cell cycle, and the intracellular reorganization, identified here in the ascidian zygote, rely on basic elements of a cell, namely: the microtubules, the actin cortex, the endoplasmic reticulum, the proteins of the cell cycle, etc. Thus, the discoveries presented here cover a broad scope, and seem adaptable to the specificities of different cell types
Ahmad, Nazem. "La cinetique cellulaire de la premiere molaire inferieure de l'embryon de souris in vivo et in vitro". Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13045.
Texto completo da fonteBOSC, CHRISTOPHE. "Caracterisation moleculaire et expression in vivo de la proteine stop de cerveau de rat, effecteur de la stabilite des microtubules neuronaux". Université Joseph Fourier (Grenoble), 1996. http://www.theses.fr/1996GRE10151.
Texto completo da fonteChneiweiss, Hervé. "Récepteurs centraux des monoamines et de neuropeptides couplés à l'adénylate cyclase de populations neuronales et astrocytaires de l'embryon de souris en culture primaire". Paris 6, 1986. http://www.theses.fr/1986PA066083.
Texto completo da fonteCohen, Edith. "Etude cytologique de la cellule neuro-epitheliale, chez l'embryon de souris, au stade initial de la differenciation neuronale". Paris 6, 1987. http://www.theses.fr/1987PA066155.
Texto completo da fonteGrinfeld, Simone. "Etude du blocage en phase G du premier cycle cellulaire, induit par les rayons X dans l'oeuf de souris". Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376057177.
Texto completo da fonteMonge, Madeleine. "Séquence d'apparition du galactosylcéramide, de la protéine de Wolfram, de la protéine basique encéphalitogène et du protéolipide de Folch dans l'oligodendrocyte et dans la myéline au cours de la myélinisation chez la souris : étude comparative de la différenciation de l'oligodendrocyte in vivo and in vitro". Paris 6, 1986. http://www.theses.fr/1986PA066245.
Texto completo da fonteAbbadie, Corinne. "Proteines nucleaires de l'ovocyte impliquees dans le developpement embryonnaire chez pleurodeles". Paris 6, 1987. http://www.theses.fr/1987PA060622.
Texto completo da fonteLelong-Rebel, Isabelle. "Etude de l'evolution de l'architecture membranaire des neurones d'embryons de poulet en culture : composition et topologie des proteines et des lipides polaires au cours du developpement cellulaire". Université Louis Pasteur (Strasbourg) (1971-2008), 1989. http://www.theses.fr/1989STR13089.
Texto completo da fonteFerraris, Corinne. "Pluripotentialité des kératinocytes épidermiques et cornéens chez les mammifères". Grenoble 1, 1994. http://www.theses.fr/1994GRE10090.
Texto completo da fonteCandelier, Jean-Jacques. "Etude de la differenciation antigenique du rein humain et de certains vertebres a l'aide d'anticorps monoclonaux". Paris 6, 1987. http://www.theses.fr/1987PA066293.
Texto completo da fonteMazzola, Clarisse. "Réalisation d'un modèle de xénogreffe rénale utilisant des embryons de poule permettant d'analyser en amont la sensibilité des cellules tumorales de chaque patient ayant un cancer du rein métastatique aux différents agents de thérapie ciblée". Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS471.
Texto completo da fonteObjective: Approximately 30% of patients with metastatic renal cancer are resistant to targeted therapy agents. The other patients will eventually develop long-term therapeutic resistances. An improvement in the clinician's ability to predict therapeutic response before treatment initiation could improve patients' prognosis. The aim of our projet was to develop a patient-derived xenograft models to be able to test the sensibility of each patient's renal tumor cells to the different available targeted therapy agent prior to treatment.Methods: The chicken embryo chorioallantoic membrane has been the base of our model. In a first phase of our work, a xenograft of human kidney tumor cells has been carried out in order to verify that the histologic and phenotypic characteristics of the original tumors were preserved in the xenografts performed on our model. As a second step, fragments of the kidney tumor speciments of 5 patients undergoing cytoreductive nephrectomy in our hospital center were grafted on our model (> 60/patient). Different targeted therapy agents were tested on the xenografts we performed.Results: The histopathologic and phenotypic characteristics of the original renal tumors were preserved in our xenografts. There was intra-tumor spatial heterogeneity in terms of sensitivity in different targeted therapy agents. There was also a nucleotide polymorphism within the different regions of each renal tumor.Conclusion: This patient-derived renal xenograft model could be useful prior to treatment for the evaluation of each patients'renal tumor cells to the different available targeted therapy agents. This model could make it possible to personalize the treatment of each metastatic kidney cancer patient, prior to systemic treatment. A prospective evaluation of our model could help assess the potential clinical benefits of its use
Simonneau, Lionel. "Etude de l'expression des cristallines et de leurs proprietes aggregatives dans les cultures de cellules epitheliales de cristallin de boeuf et de la neurotine embryonnaire de caille normale ou transformee par des retrovirus aviaires". Paris 7, 1988. http://www.theses.fr/1988PA077154.
Texto completo da fonteDufour, Sylvie. "Mécanismes adhésifs lors de la migration des cellules de la crête neurale et de la somitogenèse chez l'embryon d'oiseau". Paris 6, 1987. http://www.theses.fr/1987PA066160.
Texto completo da fonteSUIGNARD, KHASKIYE GISELE. "Contribution a l'etude des modifications des proprietes fonctionnelles affectant les cardiomyoblastes isoles en culture in vitro et des mecanismes d'action de l'acetylcholine sur le myocarde embryonnaire de poulet". Nantes, 1987. http://www.theses.fr/1987NANT2026.
Texto completo da fonteScalici, Elodie. "Les acides nucléiques circulants : biomarqueurs d'intérêt en Assistance Médicale à la Procréation". Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTT031.
Texto completo da fonteDuring the last years, the use of circulating nucleic acids as diagnostic and/or prognostic tools in cancerology was widely documented. The recent development of non-invasive prenatal testing also reveals the growing interest of these biomarkers in obstetrics and gynecology. The circulating or extracellular nucleic acids have for particularity to be easily detectable in the biological fluids of the body and there are two types: (1) Cell-free DNA (cfDNA), short or long DNA fragments resulting from cellular apoptosis and/or necrosis (2) microRNAs (miRNAs), small non-coding RNA sequences, which regulate gene expression by interfering with their mRNA targets. Since it was demonstrated that cfDNA level is abnormally increased in some pathological conditions and miRNAs are involved in the regulation of several biological processes such as folliculogenesis and steroidogenesis, these two types of nucleic acids could constitute new biomarkers of interest in Assisted Reproductive Technology. In this thesis work, we quantified the cfDNA level and analysed the expression profiles of some miRNAs by quantitative PCR, in follicular fluid (FF) samples from women undergoing in vitro fertilization (IVF) procedure. We observed significant high cfDNA levels as well as specific miRNA expression profiles in FF from women with ovarian disorders (such as polycystic ovary syndrome or low ovarian reserve). Next, we investigated the potential of circulating nucleic acids as predictive biomarkers of IVF outcomes. We demonstrated that the intra-follicular cfDNA level and some miRNA expressions were significantly associated with in vitro embryo quality and the clinical pregnancy outcome. Therefore, the circulating nucleic acids offer new diagnostic and prognostic perspectives in human infertility management
Robert, Joe͏̈lle. "Influence de divers constituants de la matrice extracellulaire sur le comportement de cellules dermiques d'embryon de poulet cultivées in vitro". Grenoble 1, 1988. http://www.theses.fr/1988GRE10110.
Texto completo da fonteFauquet, Mireille. "Etude des stades precoces de la differenciation du systeme nerveux peripherique chez l'oiseau". Paris 6, 1987. http://www.theses.fr/1987PA066162.
Texto completo da fonteMILLET, BOTTI JOELLE. "Dynamique de l'interaction fibronectine-matrice extracellulaire dans l'adhesion des fibroblastes au cours du developpement embryonnaire chez le poulet". Paris 7, 1988. http://www.theses.fr/1988PA077120.
Texto completo da fonteXue, Zhi-Gang. "Recherches sur la différenciation du système nerveux periphérique chez les oiseaux : mise en évidence et propriétés des précurseurs de type autonome présents dans les ganglions sensoriels". Paris 13, 1987. http://www.theses.fr/1987PA132008.
Texto completo da fonteCaldarelli, Paolo. "On the role of mechanical forces in embryonic self-organization". Electronic Thesis or Diss., Sorbonne université, 2021. http://www.theses.fr/2021SORUS189.
Texto completo da fonteDuring embryonic development, cells divide, migrate, rearrange, acquire different fates while organizing into a properly shaped organism. The regulation of these events is increasingly recognized to be controlled by self-organizing mechanisms. Following the seminal work of Alan Turing, who postulated, in his reaction-diffusion model, that self-organization could be controlled by the interaction between molecules, subsequent studies have focused on the identification of signaling molecules fulfilling Turing’s criteria. However, mechanical forces are generated and propagated at the tissue-scale level during morphogenesis, yet the possibility that they might act as signals in embryonic self-organization is largely underexplored. The gastrulating avian embryo, which is highly amenable to both live imaging approaches and mechanical perturbations, represents a great model to investigate the role of mechanical forces during development. Furthermore, classic experiments have demonstrated the highly regulative and self-organizing nature of early avian development: when the early epithelial disk (blastoderm) is bisected, fully formed embryos emerge from each separated part. Although recent work performed in the lab has drawn a precise mechanical picture that shapes the embryo at this stage, their role in regulating and self-organizing the embryo remains elusive, and it is the subject of this Ph.D. thesis. In collaboration with a physicist, we first formulated a mathematical model that accounts for the steady pattern of forces observed at the margin between the embryonic and extraembryonic region of the embryo. The model is based on the hypothesis that tissue mechanics at the margin self-organizes in analogy to a mechanical Turing system: tissue contractility acts as a local activator and tissue tension as a long-range inhibitor. We obtained unique predictions, which we tested experimentally to validate our model and ultimately explore the link between mechanical forces and gene expression. We found that modulation of tissue contractility at the margin alters the normal expression of Gdf1, a key morphogen in the formation of the embryo, and results in the formation of ectopic primitive streaks (primary body axis). We then perturbed the embryo mechanically. Using time-lapse imaging and laser ablation, we could orient and precisely bisect the early blastoderm. We found that in anterior halves, tissue contractility can ectopically initiate Gdf1 expression and primitive streak formation. Subsequently, to further explore the feedback between tissue mechanics and gene expression, we focused on the posterior bisected half where Gdf1 is endogenously expressed. We showed that after a few hours from the cut, the mechanical forces rescale according to the new size of the margin along with the expression domains of Gdf1. Moreover, we also found that the expression of selected embryonic territories markers follows the rescaling of the margin, suggesting an active role of tissue mechanics in allocating cell fate during development. Lastly, we showed that ectopic primitive streaks could form by placing a physical obstacle at the margin, following a prediction whereby ectopic friction is added to the motion of the tissue at the margin. This last result strongly argues against molecular diffusion as the driver of self-organization and rules out spurious events in the formation of ectopic embryos upon bisection (i.d. wound healing). Thus, this work uncovers the role of mechanical forces as signaling factors during embryonic development and demonstrates that tissue mechanics at the margin of the embryo self-organizes and underlies embryonic regulation in amniotes
Dainous, Francine. "Etude de la synthese et du metabolisme des composes a choline dans les cellules nerveuses en culture". Université Louis Pasteur (Strasbourg) (1971-2008), 1987. http://www.theses.fr/1987STR13146.
Texto completo da fonteLOMBARD, GOLLY DOMINIQUE. "Contribution a l'etude du metabolisme des glycoconjugues au cours du developpement de neurones de poulet en culture primaire : effets des gangliosides". Université Louis Pasteur (Strasbourg) (1971-2008), 1986. http://www.theses.fr/1986STR13148.
Texto completo da fonteCharpentier, Gilles. "Etude d'un facteur testiculaire qui perturbe le developpement de l'ovaire du foetus de rat, in vitro". Paris 7, 1988. http://www.theses.fr/1988PA077032.
Texto completo da fonteMiladinović, Olivera. "Molecular profiling of the embryonic hematopoietic stem cell niche". Electronic Thesis or Diss., Sorbonne université, 2023. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2023SORUS025.pdf.
Texto completo da fonteHematopoietic stem cells (HSCs) constitute a rare population of cells at the foundation of the adult hematopoietic system. During mouse ontogeny, the first adult-type HSCs are autonomously generated in the Aorta-Gonad-Mesonephros (AGM) region at mid-gestation. More precisely, HSCs emerge from aortic endothelial cells through an endothelial to hematopoietic transition. The AGM hematopoietic microenvironment is composed of diverse cell types including mesenchymal stromal cells, sympathetic nerve cells, macrophages and vascular smooth muscle cells. Although the subaortic mesenchyme is known to play a key role in AGM hematopoiesis, its molecular identity still remains elusive. To address this critical issue, we designed a laser capture strategy to isolate in the mouse embryo the dorsal and ventral aortic tissues at three developmental stages. By combining bulk and single cell transcriptomics and lineage tracing, I contributed to reveal the existence of a unique mesenchymal cell population expressing both neuronal and mesenchymal genes in the subaortic tissue at embryonic day 11.5. Using loss-of-function experiments and genetic tools in the zebrafish model that I implemented in the team, I showed that Decorin, encoding an extracellular matrix protein, is necessary for HSC development in vivo. Taken together, my PhD project provides new insights on the molecular identity of the AGM hematopoietic microenvironment and leads to the identification of potential novel HSC regulators in the embryo
Gualandris, Lydie. "Caracteristiques et role de la membrane plasmique des cellules ectoblastiques cibles de l'induction neurogene chez un amphibien urodele". Toulouse 3, 1987. http://www.theses.fr/1987TOU30031.
Texto completo da fonteLOUIS, JEAN-CLAUDE. "Mise au point, caracterisation et applications de cultures pures de neurones du systeme nerveux central". Université Louis Pasteur (Strasbourg) (1971-2008), 1986. http://www.theses.fr/1986STR13050.
Texto completo da fonteImaizumi-Scherrer, Tereza. "Etudes sur la regulation de l'expression du gene globine au cours de la differenciation des cellules erythropoietiques aviaires". Paris 7, 1987. http://www.theses.fr/1987PA077119.
Texto completo da fonteBorges, Figueiredo Ana Leonor. "Control of cell specification and migration during early frog development by PFKFB4, a key glycolysis regulator". Thesis, Paris 11, 2015. http://www.theses.fr/2015PA112107.
Texto completo da fonteEmbryonic ectoderm becomes specified into non-neural ectoderm, neural plate and neural border at the end of gastrulation. Neural border cells are the progenitors of the neural crest and placodes. The neural crest is a transient population of multipotent cells, which forms during neurulation. As the neural border elevates to form the neural tube, neural crest cells undergo an epithelial to mesenchymal transition, migrate extensively into the whole body to reach their final destinations and differentiate. Neural crest gives rise to multiple derivatives such as neurons and glia, facial cartilage, bones, melanocytes and sympatho-adrenal cells. A complex interplay of signaling and transcriptional regulations orchestrates these early patterning events. However, the first steps leading to NC formation and early specification at the NB are less understood. We analysed the NC transcriptome of frog embryos, to look for novel regulators of the early steps of NC formation. We found that the well-known glycolysis regulator PFKFB4, is expressed in early gastrula dorsal ectoderm, and in neurula neural crest cells. Here, we demonstrate that PFKFB4 regulates ectoderm specification via Akt signaling independently of glycolysis, thus demonstrating the first non-glycolytic function of PFKFB enzymes. Moreover, this regulation is essential to allow ectoderm embryonic progenitors to be patterned into neural plate, neural crest, placodes and definitive ectoderm, highlighting a novel developmental checkpoint. Moreover, we also demonstrate that PFKFB4 regulates later steps of neural crest formation. Our work highlights that regulators of cell metabolism accumulate non-metabolic related functions to control developmental steps during embryonic development
Debec, Alain. "Etude génétique de lignées cellulaires de Drosophila melanogaster". Paris 6, 1986. http://www.theses.fr/1986PA066180.
Texto completo da fonteBOULAY, JEAN-LOUIS. "Clonage et etude moleculaire du gene snail, intervenant dans la mise en place de l'axe dorso-ventral de l'embryon de drosophila melanogaster". Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13161.
Texto completo da fonteMARO, BERNARD. "Etudes sur l'organisation et le role du cytosquelette lors du developpement precoce de la souris". Paris 7, 1988. http://www.theses.fr/1988PA077223.
Texto completo da fonteHaine-Joubert, Raymonde. "Contribution à l'etude des lectines solubles : isolement et caractérisation d'une lectine soluble spécifique des résidus béta-d-galactosyles à partir d'extraits de cerveau de mammifères". Paris 13, 1987. http://www.theses.fr/1987PA132001.
Texto completo da fonteNguyen, Vinh Xuan. "Mecanismes de la resistance au gel de l'embryon de pommier (pyrus malus l. Cv. Golden delicious)". Paris 6, 1987. http://www.theses.fr/1987PA066554.
Texto completo da fonteLouerguioui, Ali. "Techniques de multiplication par clonage "in vitro" du genre eucalyptus". Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37615472r.
Texto completo da fonte