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1

Pauleikhoff, Daniel, C. Alex Harper, John Marshall e Alan C. Bird. "Aging Changes in Bruch's Membrane". Ophthalmology 97, n.º 2 (fevereiro de 1990): 171–78. http://dx.doi.org/10.1016/s0161-6420(90)32619-2.

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2

Bird, A. C. "Bruch's membrane change with age." British Journal of Ophthalmology 76, n.º 3 (1 de março de 1992): 166–68. http://dx.doi.org/10.1136/bjo.76.3.166.

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3

KARWATOWSKI, WOJCIECH S. S., TRACY E. JEFFRIES, VICTOR C. DUANCE, JULIE ALBON, ALAN J. BAILEY e DAVID L. EASTY. "Collagen and ageing in Bruch's Membrane". Biochemical Society Transactions 19, n.º 4 (1 de novembro de 1991): 349S. http://dx.doi.org/10.1042/bst019349s.

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4

Afshari, F. T., e J. W. Fawcett. "Improving RPE adhesion to Bruch's membrane". Eye 23, n.º 10 (16 de janeiro de 2009): 1890–93. http://dx.doi.org/10.1038/eye.2008.411.

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5

Pino, R. P., e E. Essner. "On the components of Bruch's membrane." Journal of Histochemistry & Cytochemistry 34, n.º 3 (março de 1986): 413. http://dx.doi.org/10.1177/34.3.3950388.

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6

Booij, J. C., D. C. Baas, J. Beisekeeva, T. G. M. F. Gorgels e A. A. B. Bergen. "The dynamic nature of Bruch's membrane". Progress in Retinal and Eye Research 29, n.º 1 (janeiro de 2010): 1–18. http://dx.doi.org/10.1016/j.preteyeres.2009.08.003.

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7

JONAS, J., Q. YOU, XY PENG, L. XU, WB WEI, Y. WANG e CX CHEN. "Macular Bruch's membrane defects in Hi". Acta Ophthalmologica 92 (20 de agosto de 2014): 0. http://dx.doi.org/10.1111/j.1755-3768.2014.f028.x.

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8

Korte, Gary E. "The Elastic Tissue of Bruch's Membrane". Archives of Ophthalmology 107, n.º 11 (1 de novembro de 1989): 1654. http://dx.doi.org/10.1001/archopht.1989.01070020732037.

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9

Hirabayashi, Yoshifumi, Osamu Fujimori e Satoru Shimizu. "Bruch's membrane of the brachymorphic mouse". Medical Electron Microscopy 36, n.º 3 (1 de setembro de 2003): 139–46. http://dx.doi.org/10.1007/s00795-003-0218-z.

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10

Rizzolo, L. J. "Basement membrane stimulates the polarized distribution of integrins but not the Na,K-ATPase in the retinal pigment epithelium." Cell Regulation 2, n.º 11 (novembro de 1991): 939–49. http://dx.doi.org/10.1091/mbc.2.11.939.

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The basement membrane stimulates the differentiation and polarity of simple transporting epithelia. We demonstrated for the retinal pigment epithelium (RPE) of chicken embryos that polarity develops gradually. Although the RPE and an immature basement membrane are established on embryonic day 4 (E4), the distribution of the Na,K-ATPase and a family of basement membrane receptors containing the beta 1 subunit of integrin is nonpolarized. The percentage of polarized cells increases gradually until cells in all regions of the epithelium are polarized on E11. During this time, the basement membrane increases in size and complexity to form Bruch's membrane. To study the ability of the basement membrane to stimulate the polarized distribution of the beta 1 integrins or the Na,K-ATPase, RPE was harvested from E7, E9, or E14 embryos and cultured on Bruch's membrane isolated (in association with the choroid) from E14 embryos. As a control, the RPE was plated on the side of the choroid lacking a Bruch's membrane. The distribution of the beta 1 integrins and the Na,K-ATPase was determined by indirect immunofluorescence. Bruch's membrane stimulated the polarized distribution of the beta 1 integrins regardless of the developmental age of the RPE even though E7 RPE is nonpolarized in vivo. To examine the role of individual matrix components, RPE was plated on matrix-coated filters. The polarized distribution of the beta 1 integrins was stimulated by laminin, collagen IV, and Matrigel but not by fibronectin. Interestingly, laminin and collagen IV are present in the basement membrane on E4 when RPE is not polarized in vivo. Under no circumstances was the distribution of the Na,K-ATPase polarized. These data indicate that the basement membrane influences the distribution of a subset of plasma membrane proteins but that other factors are required for full polarity.
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11

Greiner, Jack V., e Thomas A. Weidman. "Comparative histogenesis of Bruch's membrane (complexus basalis)". Experimental Eye Research 53, n.º 1 (julho de 1991): 47–54. http://dx.doi.org/10.1016/0014-4835(91)90143-3.

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12

Araie, Makoto, Aiko Iwase, Kazuhisa Sugiyama, Toru Nakazawa, Goji Tomita, Masanori Hangai, Yasuo Yanagi et al. "Determinants and Characteristics of Bruch's Membrane Opening and Bruch's Membrane Opening–Minimum Rim Width in a Normal Japanese Population". Investigative Opthalmology & Visual Science 58, n.º 10 (21 de agosto de 2017): 4106. http://dx.doi.org/10.1167/iovs.17-22057.

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13

Zhang, Qi, Liang Xu, Wen Bin Wei, Ya Xing Wang e Jost B. Jonas. "Size and Shape of Bruch's Membrane Opening in Relationship to Axial Length, Gamma Zone, and Macular Bruch's Membrane Defects". Investigative Opthalmology & Visual Science 60, n.º 7 (20 de junho de 2019): 2591. http://dx.doi.org/10.1167/iovs.19-27331.

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14

Newsome, David A., Warne Huh e W. Richard Green. "Bruch's membrane age-related changes vary by region". Current Eye Research 6, n.º 10 (janeiro de 1987): 1211–21. http://dx.doi.org/10.3109/02713688709025231.

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15

Tokura, T. "Age-Related Changes in Bruch's Membrane in Rats". Japanese Journal of Ophthalmology 43, n.º 4 (8 de julho de 1999): 337. http://dx.doi.org/10.1016/s0021-5155(99)00054-4.

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16

Han, Young Bock. "Anionic Sites in Bruch's Membrane of Rabbit Eyes". Ewha Medical Journal 14, n.º 4 (1991): 411. http://dx.doi.org/10.12771/emj.1991.14.4.411.

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17

Tarkkanen, Ahti, e Salme Vannas. "ULTRASTRUCTURE OF BRUCH'S MEMBRANE IN SENILE MACULAR DEGENERATION". Acta Ophthalmologica 45, n.º 5 (27 de maio de 2009): 694–98. http://dx.doi.org/10.1111/j.1755-3768.1967.tb06540.x.

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18

Tarkkanen, A., e Saline Vannas. "ULTRASTRUCTURE OF BRUCH'S MEMBRANE IN SENILE MACULAR DEGENERATION". Acta Ophthalmologica 46, n.º 3 (27 de maio de 2009): 492. http://dx.doi.org/10.1111/j.1755-3768.1968.tb02834.x.

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19

Pollack, Ayala. "Ultrastructure of Bruch's Membrane After Krypton Laser Photocoagulation". Archives of Ophthalmology 104, n.º 9 (1 de setembro de 1986): 1372. http://dx.doi.org/10.1001/archopht.1986.01050210126039.

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20

Pollack, Ayala. "Ultrastructure of Bruch's Membrane After Krypton Laser Photocoagulation". Archives of Ophthalmology 104, n.º 9 (1 de setembro de 1986): 1377. http://dx.doi.org/10.1001/archopht.1986.01050210131040.

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21

Curcio, Christine A. "Mice With Cholesterol in Bruch's Membrane: Have We Arrived?" Investigative Opthalmology & Visual Science 55, n.º 11 (17 de novembro de 2014): 7296. http://dx.doi.org/10.1167/iovs.14-15858.

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22

Sheraidah, Ghassan, Robert Steinmetz, Joseph Maguire, Daniel Pauleikhoff, John Marshall e Alan C. Bird. "Correlation between Lipids Extracted from Bruch's Membrane and Age". Ophthalmology 100, n.º 1 (janeiro de 1993): 47–51. http://dx.doi.org/10.1016/s0161-6420(13)31712-6.

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23

Tokura, T. "Changes in Bruch's Membrane in Experimental Hypercholesteremia in Rats". Japanese Journal of Ophthalmology 43, n.º 4 (8 de julho de 1999): 337–38. http://dx.doi.org/10.1016/s0021-5155(99)00055-6.

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24

Pauleikhoff, D., J. C. Chen, I. H. Chisholm e A. C. Bird. "Choroidal Perfusion Abnormality With Age-Related Bruch's Membrane Change". American Journal of Ophthalmology 109, n.º 2 (fevereiro de 1990): 211–17. http://dx.doi.org/10.1016/s0002-9394(14)75989-6.

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25

Zhu, Zhi-Ren, Randi Goodnight, Tatsuro Ishibashi, Nino Sorgente, Thomas E. Ogden e Stephen J. Ryan. "Breakdown of Bruch's Membrane after Subretinal Injection of Vitreous". Ophthalmology 95, n.º 7 (julho de 1988): 925–29. http://dx.doi.org/10.1016/s0161-6420(88)33074-5.

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26

Feeney-Burns, Lynette, e Mark R. Ellersieck. "Age-Related Changes in the Ultrastructure of Bruch's Membrane". American Journal of Ophthalmology 100, n.º 5 (novembro de 1985): 686–97. http://dx.doi.org/10.1016/0002-9394(85)90625-7.

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27

Gullapalli, Vamsi K., Ilene K. Sugino, Yancy Van Patten, Sumit Shah e Marco A. Zarbin. "Impaired RPE survival on aged submacular human Bruch's membrane". Experimental Eye Research 80, n.º 2 (fevereiro de 2005): 235–48. http://dx.doi.org/10.1016/j.exer.2004.09.006.

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28

Fiskaadal, H. J., B. Nicolaissen, A. Ringvold e O. Naess. "In vitro ingrowth of choroidal cells on Bruch's membrane". Acta Ophthalmologica 70, n.º 3 (27 de maio de 2009): 297–302. http://dx.doi.org/10.1111/j.1755-3768.1992.tb08567.x.

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29

STARITA, CARLA, ALI A. HUSSAIN, SERGIO PAGLIARINI e JOHN MARSHALL. "Hydrodynamics of Ageing Bruch's Membrane: Implications for Macular Disease". Experimental Eye Research 62, n.º 5 (maio de 1996): 565–72. http://dx.doi.org/10.1006/exer.1996.0066.

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30

Gottsch, John D. "Light-Induced Deposits in Bruch's Membrane of Protoporphyric Mice". Archives of Ophthalmology 111, n.º 1 (1 de janeiro de 1993): 126. http://dx.doi.org/10.1001/archopht.1993.01090010130039.

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31

Willenberg, Wolfgang, Marcus Stoffel, Dieter Weichert e Gabriele Thumann. "Investigation of regenerative tissue for replacing the Bruch's membrane". PAMM 12, n.º 1 (dezembro de 2012): 93–94. http://dx.doi.org/10.1002/pamm.201210038.

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32

Zarbin, M. A. "Age-Related Macular Degeneration: Review of Pathogenesis". European Journal of Ophthalmology 8, n.º 4 (outubro de 1998): 199–206. http://dx.doi.org/10.1177/112067219800800401.

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Age-related macular degeneration is a condition (a) characterized by accumulation of membranous debris on both sides of the retinal pigment epithelium (RPE) basement membrane. Clinical manifestations of drusen, atrophy of the RPE/choriocapillaris, RPE detachment, and choroidal new vessel (CNV) formation occur after age 50 years. A hypothetical pathogenic sequence of events consistent with known data is: 1) RPE dysfunction (e.g., precipitated by an inherited susceptibility and/or environmental exposure); 2) accumulation of intracellular material in the RPE (e.g., accumulation of normal substrate material that is not enzymatically degraded properly vs. abnormal substrate material); 3) abnormal accumulation of extracellular material (basal laminar and basal linear deposit); 4) change in Bruch's membrane composition (e.g., increased lipid deposition and protein crosslinking); 5) change in Bruch's membrane parmeability to nutrients (e.g., impaired diffusion of water soluble plasma constituents across Bruch's membrane); and 6) response of the RPE to metabolic distress (i.e., atrophy vs. CNV growth). Histopathological and clinical studies indicate that areas of choroidal ischemia often are seen near CNVs in AMD patients. In response to decreased oxygen delivery/metabolic “distress”, the RPE may elaborate substances leading to CNV growth. Perhaps RPE atrophy, followed by choriocapillaris and photoreceptor atrophy, is a response to decreased nutrients/increasing metabolic abnormalities in areas of excessive accumulation of extracellular debris. Unanswered questions regarding AMD include: 1) is AMD an ocular manifestation of a systemic disease or purely an ocular disease?; 2) what determines whether CNVs vs.atrophy of the RPE-choriocapillaris-photoreceptors develops?; and 3) what induces the maturation of CNVs into an inactive scar, and what limits the growth of most CNVs to the area centralis?
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33

Khodamoradi, Maedeh, Mahnaz Eskandari, Hamid Keshvari e Reza Zarei. "An electro-conductive hybrid scaffold as an artificial Bruch's membrane". Materials Science and Engineering: C 126 (julho de 2021): 112180. http://dx.doi.org/10.1016/j.msec.2021.112180.

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34

Cho, Myung Ho, Hyun-kyung Cho e Ji Woong Lee. "Bruch's Membrane Minimum Rim Width in a Normal Korean Population". Journal of the Korean Glaucoma Society 9, n.º 1 (2020): 24. http://dx.doi.org/10.36299/jkgs.2020.9.1.24.

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35

Chen, L. "Distribution of the collagen IV isoforms in human Bruch's membrane". British Journal of Ophthalmology 87, n.º 2 (1 de fevereiro de 2003): 212–15. http://dx.doi.org/10.1136/bjo.87.2.212.

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36

Enders, Philip, Andreas Bremen, Friederike Schaub, Manuel M. Hermann, Michael Diestelhorst, Thomas Dietlein, Claus Cursiefen e Ludwig M. Heindl. "Intraday Repeatability of Bruch's Membrane Opening-Based Neuroretinal Rim Measurements". Investigative Opthalmology & Visual Science 58, n.º 12 (11 de outubro de 2017): 5195. http://dx.doi.org/10.1167/iovs.17-22812.

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37

Nakanishi, Masataka, Rhonda Grebe, Imran A. Bhutto, Malia Edwards, D. Scott McLeod e Gerard A. Lutty. "Albumen Transport to Bruch's Membrane and RPE by Choriocapillaris Caveolae". Investigative Opthalmology & Visual Science 57, n.º 4 (26 de abril de 2016): 2213. http://dx.doi.org/10.1167/iovs.15-17934.

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38

Gampa, Amulya, Gautam Vangipuram, Zainab Shirazi e Heather E. Moss. "Quantitative Association Between Peripapillary Bruch's Membrane Shape and Intracranial Pressure". Investigative Opthalmology & Visual Science 58, n.º 5 (26 de maio de 2017): 2739. http://dx.doi.org/10.1167/iovs.17-21592.

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39

Pruett, Ronald C., John J. Weiter e Robert B. Goldstein. "Myopic Cracks, Angioid Streaks, and Traumatic Tears in Bruch's Membrane". American Journal of Ophthalmology 103, n.º 4 (abril de 1987): 537–43. http://dx.doi.org/10.1016/s0002-9394(14)74277-1.

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40

Killingsworth, M. C. "Age-related components of Bruch's membrane in the human eye". Graefe’s Archive for Clinical and Experimental Ophthalmology 225, n.º 6 (novembro de 1987): 406–12. http://dx.doi.org/10.1007/bf02334166.

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41

Killingsworth, M. C., J. P. Sarks e S. H. Sarks. "Macrophages related to Bruch's membrane in age-related macular degeneration". Eye 4, n.º 4 (julho de 1990): 613–21. http://dx.doi.org/10.1038/eye.1990.86.

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42

Dastgheib, Kourosh. "Granulomatous Reaction to Bruch's Membrane in Age-Related Macular Degeneration". Archives of Ophthalmology 112, n.º 6 (1 de junho de 1994): 813. http://dx.doi.org/10.1001/archopht.1994.01090180111045.

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43

Braekevelt, C. R. "Fine structure of the retinal epithelium, Bruch's membrane, and choriocapillaris of the pigeon (Columba livia)". Canadian Journal of Zoology 67, n.º 4 (1 de abril de 1989): 795–800. http://dx.doi.org/10.1139/z89-116.

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As part of a comparative morphological study, the fine structure of the retinal pigment epithelium, the choriocapillaris, and Bruch's membrane (complexus basalis) has been studied by light and electron microscopy in the pigeon (Columba livia). In this species the retinal pigment epithelium consists of a single layer of cuboidal cells, which show numerous very deep basal (scleral) infoldings and extensive apical (vitreal) processes enclosing photoreceptor outer segments. These epithelial cells are joined laterally by prominent basally located tight junctions. Internally, smooth endoplasmic reticulum is the most abundant cell organelle with only small amounts of rough endoplasmic reticulum present. Polysomes are abundant as are mitochondria, which often display a ring-shaped structure. The cell nucleus is large and vesicular. Melanosomes are plentiful in both the apical region of the cell body and within the apical process in the light-adapted condition. Myeloid bodies are large and numerous and very often have ribosomes on their outer border. Bruch's membrane shows a pentalaminate structure but with only a poorly represented central elastic lamina. Profiles of the choriocapillaris are relatively small and not overly abundant. The endothelium of the choriocapillaris, while extremely thin facing the retinal epithelium, is but minimally fenestrated.
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44

Hewitt, A. Tyl, e David A. Newsome. "Altered synthesis of Bruch's membrane proteoglycans associated with dominant retinitis pigmentosa". Current Eye Research 4, n.º 3 (janeiro de 1985): 169–74. http://dx.doi.org/10.3109/02713688509000846.

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45

Kaya, Abdullah, Cihan Büyükavşar e Yavuz Çakır. "Bruch's membrane does not seem to have a role in myopization". Acta Ophthalmologica 95, n.º 1 (7 de abril de 2016): e74-e74. http://dx.doi.org/10.1111/aos.13045.

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46

Pollack, A., W. J. Heriot e P. Henkind. "Cellular Processes Causing Defects in Bruch's Membrane Following Krypton Laser Photocoagulation". Ophthalmology 93, n.º 8 (agosto de 1986): 1113–19. http://dx.doi.org/10.1016/s0161-6420(86)33614-5.

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47

Stoyukhina, A. S., e S. U. Nechesnyuk. "Correlations between OCT and histological findings in choroidal melanomas". Modern technologies in ophtalmology, n.º 3 (15 de julho de 2021): 401–7. http://dx.doi.org/10.25276/2312-4911-2021-3-401-407.

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It is known that OCT-detected retinal changes are comparable with histology resalts. Choroidal structure on EDI-OCT also comparable with histology. Purpose. To compare OCT-changes with pathomorphology in same microscopic sections. Material and methods. The analysis of OCT tomograms of 5 patients with choroidal melanomas (CM), who subsequently underwent primary enucleation. The patients age was 55,2±10,57 years. The maximum CM elevation is 4,85±1,76 mm, the maximum diameter is 13,09±4,14 mm. Results and discussion. The correlation of tomographic and histological picture was obtained in the following signs: signs of destruction of Bruch's membrane, the presence of hyperreflective changes at the RPE level, photoreceptors changes, the presence of neuroepithelial detachment, the presence of intraretinal cavities. Partial correlation - for signs of the presence of subretinal transudate and infiltration of the outer layers of the retina. No correlation was obtained for the signs of infiltration of the inner retina layers and the inner limitans membrane breakthrough with CM dissemination on a retinal surface. Conclusions. Comparison of OCT signs of MC with pathomorphological studies in 5 enucleated eyes made it possible to expand the interpretation of signs of CM spreading on OCT beyond the Bruch's membrane with the tumor growth zones formation in the retina. Key words: choroidal melanoma, optical coherence tomography of the retina, histological examination.
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48

Ramesh, PrasannaV, ShruthyV Ramesh, MeenaK Ramesh, Ramesh Rajasekaran e Sathyan Parthasarathi. "Striking the metronome in morphometric analysis of glaucoma - Shifting from Bruch's Membrane Opening - Horizontal Rim Width (BMO-HRW) to Bruch's Membrane Opening - Minimum Rim Width (BMO-MRW)". Indian Journal of Ophthalmology 69, n.º 4 (2021): 1005. http://dx.doi.org/10.4103/ijo.ijo_2879_20.

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49

Lin, Wen-Lang. "Immunogold localization of extracellular matrix molecules in Bruch's membrane of the rat". Current Eye Research 8, n.º 11 (janeiro de 1989): 1171–78. http://dx.doi.org/10.3109/02713688909000042.

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50

Vijayasekaran, Sarojini, Dao-Yi Yu, Ian L. McAllister, Chris Barry e Ian J. Constable. "Significance of Bruch's membrane in the creation of iatrogenic chorioretinal venous anastomosis". Current Eye Research 13, n.º 1 (janeiro de 1994): 29–33. http://dx.doi.org/10.3109/02713689409042395.

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