Artigos de revistas sobre o tema "Baz Bahadur"
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Kuhn, Julia, Michel Mandjes e Thomas Taimre. "EXACT ASYMPTOTICS OF SAMPLE-MEAN-RELATED RARE-EVENT PROBABILITIES". Probability in the Engineering and Informational Sciences 32, n.º 2 (16 de janeiro de 2017): 207–28. http://dx.doi.org/10.1017/s0269964816000541.
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Relying only on the classical Bahadur–Rao approximation for large deviations (LDs) of univariate sample means, we derive strong LD approximations for probabilities involving two sets of sample means. The main result concerns the exact asymptotics (asn→∞) of$$ {\open P}\left({\max_{i\in\{1,\ldots,d_x\}}\bar X_{i,n} \les \min_{i\in\{1,\ldots,d_y\}}\bar Y_{i,n}}\right),$$with the${\bar X}_{i,n}{\rm s}$(${\bar Y}_{i,n}{\rm s}$, respectively) denotingdx(dy) independent copies of sample means associated with the random variableX(Y). Assuming${\open E}X \gt {\open E}Y$, this is a rare event probability that vanishes essentially exponentially, but with an additional polynomial term. We also point out how the probability of interest can be estimated using importance sampling in a logarithmically efficient way. To demonstrate the usefulness of the result, we show how it can be applied to compare the order statistics of the sample means of the two populations. This has various applications, for instance in queuing or packing problems.
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Aripin, Norizah, e Nurshafizah Suhairi. "“DOCUMENTARY THE CURSE BAN PECAH”". International Journal of Law, Government and Communication 5, n.º 18 (10 de março de 2020): 43–56. http://dx.doi.org/10.35631//ijlgc.518005.
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The study focused on the publication of a documentary entitled “The Curse of Ban Pecah” to address some of the concerns of the tragedy and public opinion on the devastation that has occurred over Kampung Sungai Baharu and the surrounding area. In general, the documentary "The Curse of Ban Pecah" is historical and mythical about the existence of "The Curse of Ban Pecah" which raises the question of its existence. The history of the curse is a matter of ignorance and the story of orphans who have been betrayed by their uncles because of their wealth. In this regard, the documentary was produced for 10 minutes showing the history and development of the “Ban Pecah” in Tanjung Piandang, Perak. The publication of the documentary was conducted in advance of interviews with some of the villagers. Observations are also made in the area for information before filming in the area. The production of this video was uploaded on “YouTube Sintok Media” for public viewing. Overall, the study shows that this place has begun to develop and, in addition to the story behind the name "Ban Pecah", can provide lessons for the community and can be taught in the future.
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Habib, Abbas Ghaffari, e Seyed Hadi Khatami. "Survey of the Water Quality of the Bahar County Streams (Iran) by NSFWQI". Environment Conservation Journal 16, SE (5 de dezembro de 2015): 395–403. http://dx.doi.org/10.36953/ecj.2015.se1646.
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In Bahar County (Iran), rivers are among the important sources of water for the agricultural sector. Therefore, this research evaluated the parameters of temperature, pH, Total Dissolved Solids (TDS), turbidity, nitrate, total phosphate, dissolved oxygen (DO), Biological Oxygen Demand (BOD5), and fecal coliform at five stations for five months (from February 2015 to June 2015) to determine water quality in the rivers. Based on this evaluation, the NSFWQI index was calculated and, finally, the routes of the rivers were zoned. The best water quality was recorded at Station Number 3 with the NSFWQI Value of 80 in January, and the worst at Station Number 5 (latgah) with the NSFWQI Value of 37 in June. Based on the mean NSFWQI indices, water quality was Medium at Stations Number 1, 2, and 4, good at Station Number 3, and bad at Station number 5.
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Singh, Anjali, Sruthi Bhaskaran e Anshuja Singla. "Outcome and complications of self-administration of over-the-counter abortion pills: an observational study in a tertiary care hospital of a medical college in New Delhi". International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, n.º 8 (26 de julho de 2021): 3148. http://dx.doi.org/10.18203/2320-1770.ijrcog20212971.
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Background: Due to unrestricted free availability of abortion pills, despite of national policies, guidelines and medical termination of pregnancy (MTP) act, unsafe abortions by self-administration of these drugs for termination of unwanted pregnancies without prescription are becoming common in our country, leading to associated morbidity and mortality.Methods: A prospective Observational study was done at Guru Teg Bahadur hospital, university college of medical sciences, New Delhi, from November 2019 to April 2020, in the department of gynecology and obstetrics, on women visiting the outpatient department and casualty department with the history of self-administration of medical termination pills without prescription. This study was done to study the outcome and complications occurring due to self-administration of over-the-counter abortion pills that are freely available in the market. 95 women were included in study and data was collected regarding age, education level, parity, presenting complaints, complications and their management. Descriptive analysis of the collected data was done.Results: In this study 95 women were included 71.6% took pills before 8 weeks of gestation, 1% took in second trimester. 46.3% landed up in incomplete abortion and 33.68% needed surgical evacuation, 8.42% had ectopic out, 2.1% had scar site pregnancy and 7.36% needed laparotomy, 1.05% had rupture uterus followed by abortion pill intake while 1.05% suffered from acute kidney injury (AKI). There was no ICU admission nor any mortality.Conclusions: There is urgent need of strict legislation to curtail this bad practice and free availability of over-the-counter abortion pills which leads to unexpected morbidity and mortality, such drugs should be given only by health care providers under supervision, there is need of community level awareness so as to impart knowledge regarding this problem.
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Hikmawati, Masna, Ulfa Amalia e Nur Ilmi Kamiliah. "Analisis Ilmu Arudl dan Qawafi dalam Kitab Tanwīr al-Qāri' Karya Muhammad Mundzir Nadzir". JILSA (Jurnal Ilmu Linguistik dan Sastra Arab) 6, n.º 2 (27 de outubro de 2022): 162–75. http://dx.doi.org/10.15642/jilsa.2022.6.2.162-175.
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Ilmu Arudl dan Qawafi merupakan dua ilmu yang ada di bidang sastra Arab yang saat ini kurang diminati oleh kalangan pelajar, karena dianggap terlalu terikat dengan aturan yang baku dan mengekang dalam mengungkapkan ekspresi serta emosi. Namun demikian, tidak dapat dipungkiri bahwa kedua ilmu (Arudl dan Qawafi) ini telah menjadi mutiara dalam sejarah peradaban Arab. Penelitian ini berusaha menganalisa syair dalam kitab Tanwir al-Qari’ karya Muhammad Mundzir Nadzir yaitu kitab tajwid yang syairnya berbahasa Jawa yang ditinjau dari Ilmu Arudl dan Ilmu Qawafi. Penelitian ini adalah deskriptif kualitatif yaitu memaparkan hasil analisis puisi ini ditinjau dari Ilmu Arudl dan Ilmu Qawafi. Hasil penelitian menunjukkan bahwa syair kitab Tanwir al-Qari’ menggunakan bahar Rajaz. Dilihat dari segi Ilmu Arudl, ada beberapa yang sahih, dan ada beberapa yang fasid. Dalam syair ini juga terdapat beberapa zihaf yang digunakan, antara lain; khabn, khazm, Thayy, dan khabl. Dari segi ilmu Qawafi, syair dalam bab nun sukun ini dibagi menjadi dua macam, yaitu bentuk Qawafi dan jenis qafiyah. Sedangkan dari segi bentuk Qawafi, syair kitab Tanwir al-Qari’ bab nun sukun ini menggunakan dua jenis huruf Qafiyah, yaitu ar-Rawiy (Rawiy Mutlak dan Rawiy Muqayyad) dan al-Wasl.
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Mora, Yenni Sofyan. "EVALUASI DIMENSI UNIT ISTALASI PENGOLAHAN AIR LIMBAH DOMESTIK RUMAH SAKIT dr. ERNALDI BAHAR KOTA PALEMBANG". Jurnal Dampak 12, n.º 2 (1 de julho de 2015): 127. http://dx.doi.org/10.25077/dampak.12.2.127-136.2015.
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Penelitian ini bertujuan menganalisa karakteristik air limbah domestik serta mengevaluasi kriteria teknis bangunan unit pengolahan air limbah domestik yang ada di RS ERBA apakah sudah memenuhi standar. Dilakukan di wilayah Rumah Sakit dr. Ernaldi bahar yang berlokasi di Jalan Tembus Terminal Km 12 No 2 RT 20 RW 04 Kecamatan Alang-Alang Lebar Kota Palembang dari bulan November 2014 - Maret 2015. Metode Peneliti melaksanakan penelitian pada air limbah domestik, bangunan IPAL domestik dan tangki septik ruang rawat inap menggunakan metode observasional, Metode komparatif (perbandingan) mengacu pada Keputusan Menteri Negara Lingkungan Hidup Nomor : Kep-58/MENLH/12/1995 dan Kriteria Desain bangunan unit pengolahan air limbah berdasarkan pada Kriteria Teknis Prasarana & Sarana Pengolahan Air Limbah PU. Hasil penelitian menunjukan bahwa kualitas effluen limbah cair IPAL domestik rumah sakit telah memenuhi standar baku mutu limbah cair yang dikeluarkan oleh KepMen LH No.Kep-58/MENLH/12/1995 kecuali untuk parameter amoniak (NH3N) tinggi. debit air limbah melebihi kapasitas tampung pada IPAL domestik dan tangki septik. Kesimpulan dari penelitian ini adalah strategi perencaaan teknis dimensi pada bangunan bak kontrol, IPAL STP Biotech dan Tangki Septik.Kata kunci : Air limbah, Evaluasi IPAL Domestik, Tangki Septik
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Surya Putra, Firman. "Tathbiq Maslahah Menurut Ibn Daqiq Al-‘Id (625-702 H), dalam Bab Munakahat, (Studi terhadap Kitab Ihkam Al-Ahkam Syarh ‘Umdah Al-Ahkam)". Jurnal An-Nahl 8, n.º 1 (30 de junho de 2021): 26–42. http://dx.doi.org/10.54576/annahl.v8i1.27.
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Tulisan ini membahas tentang mashlahah yang pada zahirnya merupakan ushul atau dalil yang dipertentangkan. Tetapi pada hakikatnya mashlahah secara langsung ataupun tidak langsung telah diterapkan dalam syari’at Islam. Dan jika diperhatikan secara seksama maka dari setiap syari’at yang Allah SWT tetapkan ada mashlahah untuk manusia, baik Allah SWT taklifkan dalam keadaan normal (tidak ada udzur syar’i) atau dalam keadaan darurat. Imam Ibn Daqiq al-‘Id (625-702 H), diakui para ulama sebagai mujtahid mustaqil (indefenden), kendatipun menguasai dua mazhab, mazhab Maliki dan mazhab Syafi’i. Namun dalam berijtihad selalu mempunyai pendapat dan sisi pandang tersendiri dan tidak muqallid terhadap dua mazhab yang beliau kuasai, terutama dalam kitabnya Ihkam al-Ahkam Syarh ‘Umdatu al-Ahkam. Lalu bagaimana perhatian beliau terhadap mashlahah terutama pada bab Munakahat, apakah mengenyampingkan mashlahah atau sebaliknya? Untuk menjawab permasalahan di atas, dipergunakan penelitian kepustakaan, dengan mengumpulkan data primer (kitab Ihkam al-Ahkam Syarh ‘Umdatu al-Ahkam) dan data skunder. Peniliti mencoba menggambarkan pendapat-pendapat Ibnu Daqiq al-’Id dan pendapat ulama lain pada satu fokus permasalahan, kemudian menganalisa pendapat-pendapat tersebut..Penulis melihat Ibn Daqiq dalam berijtihad selalu memperhatikan sisi mashlahah yang disesuaikan dengan Qasd al-Syari’mashlahah yang diterapkan Imam Ibn Daqiq tidak terlepas dari keadaan yang beliau jalani semasa hidupnya dari berbagai permasalahan yang dialami masyarakat saat itu, mulai dari segi sosial, ekonomi, politik dan yang lainnya. Perhatian terhadap mashlahah suatu keniscayaan dan relevan dengan zaman dengan catatan tanpa mengedepankan hawa nafsu, karena permasalahan selalu terjadi dengan bersifat baharu terutama dalam bab Munakahat.
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Gunawan, Fahmi, Adnan Mahmud e Nirwan Umasugi. "PERAN NAZHIR DALAM PENGELOLAAN WAKAF PRODUKTIF PADA YAYASAN KESEJAHTRAAN NURUL BAHAR TOMALOU KOTA TIDORE KEPULAUAN". Indonesian Journal of Shariah and Justice 2, n.º 2 (29 de dezembro de 2022): 199–228. http://dx.doi.org/10.46339/ijsj.v2i2.39.
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Waqf management lies in the existence of waqf managers, especially nazhir and a solid work team to maximize the role of waqf. If waqf is managed professionally, then it will become a potential Islamic institution that functions to fund and develop the people's economy. Therefore, the progress of waqf is largely determined by the good and bad management of waqf management. And also the waqf institution is a religious institution that has potential and economic benefits that need to be managed effectively and efficiently for the benefit of worship and advancing public welfare. The social welfare of the community that is expected cannot be realized optimally if Nazhir does not carry out his duties optimally, what is Nazhir's role in managing productive waqf at the Nurul Bahar Tomalou Welfare Foundation, Tidore City, the purpose of management is to realize the welfare of the people. Waqf has a dual function, namely the function of worship and social function. In the function of worship, waqf aims to be a provision for wakif in the afterlife because the reward continues to flow during mawqûf bih. In its social function, waqf plays a role in creating the welfare of the people when the nazhir's role is in optimal management by the nazhir. In accordance with the law. The research used is field research, namely research that seeks to find primary data obtained directly from productive waqf implementation activities. The results of research on the role of a nazir on waqf management carried out by nazirs in a professional manner provide opportunities for waqf development to be more productive, as well as provide opportunities for the application of modern management principles. Within this framework, nazhir should try to show the best possible waqf performance.
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Brendan Kung, Kevin, Ramalinggam Rajamanickam e Muhammad Helmi Md. Said. "Kebolehterimaan Keterangan Anjing Pengesan di Amerika Syarikat". JURNAL UNDANG-UNDANG DAN MASYARAKAT 34, n.º 1 (29 de maio de 2024): 64–79. http://dx.doi.org/10.17576/juum-2024-3401-05.
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Dengan teknologi yang semakin maju sepantas kilat, teknik penyiasatan forensik yang baharu telah dibangunkan. Walau bagaimanapun, beberapa sabitan dalam kes jenayah masih bergantung pada teknik lama dan tradisional, seperti penggunaan anjing pengesan atau K-9. Umum mengetahui bahawa, anjing ialah haiwan yang pintar dan mempunyai deria bau yang tajam. Pada awalnya, mahkamah di Amerika Syarikat teragak-agak untuk menerima keterangan anjing pengesan dan telah meluahkan kebimbangan, khususnya apabila anjing membuat inferens. Namun, keterangan anjing pengesan telah diterima oleh mahkamah di Amerika Syarikat sejak satu abad yang lalu. Memandangkan anjing tidak boleh masuk ke kandang saksi untuk memberikan keterangan di mahkamah, pengendali anjing dibenarkan untuk memberikan keterangan bagi anjingnya berhubungan dengan penjejakan dan pengesanan. Mahkamah di bidang kuasa lain telah menganggap pengendali anjing sebagai saksi pakar. Hal ini menyebabkan pendapat mereka boleh diterima sebagai keterangan pakar. Artikel ini mengupas isu berkaitan dengan penggunaan anjing pengesan oleh agensi penguatkuasaan undang-undang di Amerika Syarikat. Selain itu, artikel ini juga membincangkan kebolehterimaan keterangan anjing pengesan oleh mahkamah di Amerika Syarikat. Metodologi yang digunakan dalam artikel ini adalah deskriptif, doktrinal, analitis dan preskriptif kerana keputusan kes, jurnal dan buku berkaitan dengan keterangan anjing pengesan dianalisis.
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Abdel Karim, Maria. "Queer representation in Arab and Middle Eastern Films". Alphaville: Journal of Film and Screen Media, n.º 20 (27 de janeiro de 2021): 71–86. http://dx.doi.org/10.33178/alpha.20.06.
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Queer representations have been present since the 1930s in Arab and Middle Eastern cinema, albeit always in coded forms. However, the idea of homosexuality or queerness in the Middle East is still not tolerated due to religious, political, social and cultural reasons. Middle Eastern filmmakers who represent homosexual relations in their films could face consequences ranging from censorship to punishment by the State or religious extremists. This article explores the representation of lesbians in three transnational Middle Eastern women’s films: Caramel (Sukkar banat, 2007) by Nadine Labaki, set in Lebanon, Circumstance (2011) by Maryam Keshavarz, set in Iran, and In Between (Bar Bahar, 2016) by Maysaloun Hamoud, set in Israel/Palestine. It analyses the position the female lesbian protagonists occupy in the narrative structure and their treatment within the cinematic discourse. The article will examine mise-en-scène elements and compare each director’s stylistic and directorial approach in representing homosexuality within different social and cultural contexts. It will also prompt discussions related to queer identity, queer feminism, women’s cinema, audience reception and spectatorship within the Middle East.
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Araya Vergara, José F. "Análisis de la carta geomorfológica de la cuenca del Mapocho". Investigaciones Geográficas, n.º 32 (1 de janeiro de 1985): 31. http://dx.doi.org/10.5354/0719-5370.1985.27693.
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The Mapocho basin (Central de Chile) is divided into two morphotectonic styles by the Mapocho fracture. ln the northern section, of the Santiago depression an intense monoclinal warping anda deep alveolar excavation evidence important uplift of the western border. ln the southern section, the asymetry is stronger than the former one and inverse, giving a fault angle depression. This fracturation of the depression's bottom has affected both the conditions of sedimentation and the drainage patterns, causing antecedence phenomena and antagonistic effects between tectodynamics and external morphogenesis. Concerning present tectonics and seismicity, the presence both of different tectonic compartments and depositional landforms in the depression, is possibly more important than the faults themselves in the explanation of the distribution of seismic intensities. ln the northern section of the depression there is a characteristic combination between alluvial cones and "glacis" (bahadas). Moreover, marshy terraces correspond to bad drainage conditions. ln the southern section, in exchange, the central compartments are occupied by proximal cones and dista1 terraces. Slopes are presented as slope systems anda new classification supported on the structure and the external dynamics is used. At the same time, the concept of dissection balance allows relate slopes and talweg dynamics. Therefore, it can be known if the more important morphogenetic processes are present or ancient. So, the fluvial landforms at the depression's bottom are inherited. In the present conditions it is unlikely the transport of coarse sediments from the high mountain toward the depression. Moreover, the torrentialand sheet wash morphologic systems are also inherited. Present through put of material from active slopes toward beds and depressions is possible only during heavy storms of rain y years.
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Saputri, Ayu, e Ismar Agustin. "Case Study: Nursing Implementation of Taking Medication in Patients with Auditory Hallucinations". International Journal Scientific and Professional (IJ-ChiProf) 2, n.º 2 (31 de maio de 2023): 18–22. http://dx.doi.org/10.56988/chiprof.v2i2.52.
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Medication adherence is the level of individual accuracy with medical advice that describes the use of medication according to the instructions and instructions on the prescription, including using it at the correct time. Patients who are not compliant in taking medication tend to experience relapses easily. Frequent relapses in sufferers result in bad effects on the brain which makes it difficult for sufferers to recover. This research aims to obtain an overview of the level of adherence to taking medication and provide knowledge about the importance of taking medication in patients with sensory perception disorders, auditory hallucinations. This case study research is descriptive in nature, with an implementation method using nursing care which was carried out on 8-15 April 2021, the case study subjects were two patients with sensory perception disorders, auditory hallucinations in the Cempaka ward of the Ernaldi Bahar Hospital, South Sumatra Province. After implementing it on patients, the result was that taking medication regularly was very effective in controlling hallucinations because patients were taught to know the five correct principles in taking medication, namely the correct patient, the correct drug, the correct dose, the correct method/route of administration, and the correct time for administering the drug. where compliance occurs if the rules for taking prescribed medication and administering it in the hospital are followed correctly
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Omar, Ani, e Lajiman Janoory. "Jati Diri Orang Melayu menerusi novel Malaisie karya Henri Fauconnier". Jurnal Peradaban Melayu 12 (9 de dezembro de 2017): 28–39. http://dx.doi.org/10.37134/peradaban.vol12.4.2017.
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Sejak 84 tahun lalu, novel berteraskan rakaman sejarah mengenai citra kehidupan, budaya, adat resam, keindahan bahasa dan kesusasteraan Melayu daripada kaca mata lelaki Perancis, Henri Fauconnier sudah diterbitkan dalam bahasa Perancis. Novel Malaisie telah diterjemahkan ke pelbagai bahasa dunia termasuk bahasa Inggeris dengan tajuk The Soul of Malaya oleh penterjemahnya, Eric Sutton. Nurani Tanah Melayu tajuk novel Malaisie yang diterjemahkan ke dalam bahasa Melayu oleh Sasterawan Negara Prof. Emeritus Dr. Muhammad Haji Salleh, menanggapi dimensi baharu kehidupan yang dilalui dua pengurus estet, Lescale dan Rolain di Kuala Sampah, Selangor yang secara perlahan-lahan menyesuaikan diri, sekali gus mempelajari adat budaya pelbagai kaum di Tanah Melayu. Artikel ini selanjutnya menampilkan bagaimana Fauconnier mencerminkan realiti sepanjang beliau berkelana ke Tanah Melayu bermula tahun 1905 untuk memulakan penanaman getah. Pelbagai kisah menarik merangkumi kehidupan pelbagai kaum dimuatkan dalam novel ini. Lebih menarik, banyak pantun Melayu yang menghiasi setiap bab, malah Fauconnier turut menulis bahawa beliau terpikat dengan bait indah dan kiasan dalam khazanah puisi tradisional Melayu yang menunjukkan kesantunan masyarakatnya dalam berbahasa sekali gus menampilkan jati diri penuturnya. Keindahan sastera Melayu menerusi watak pembantu Lescale, iaitu Ngah dan Smail yang mengajaknya membaca buku dongeng lama seperti Cerita Kutu di Dalam Hutan dan Pak Belalang pula menunjukkan kebanggaan masyarakat dulu dalam memartabatkan bahasa dan kesusasteraan. Secara keseluruhannya Nurani Tanah Melayu adalah simbolik kepada kekuatan Melayu yang selama ini sering dipandang rendah oleh masyarakatnya sendiri, sedangkan ia dihormati oleh orang asing yang mengambil peluang mendalami keunikan budaya dan keseniannya. Dapatan kajian ini berupaya membuatkan nurani dan minda masyarakat supaya teguh kepada akarnya, tegar dalam menjaga kedaulatan bangsa dan lebih patriotik seperti saratnya cinta Fauconnier kepada Tanah Melayu.
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NAGHAVI, Mohammad Reza, Mahmoud TOORCHI, Mohammad MOGHADDAM e Mohammad Reza SHAKIBA. "Evaluation of Diversity and Traits Correlation in Spring Wheat Cultivars under Drought Stress". Notulae Scientia Biologicae 7, n.º 3 (21 de setembro de 2015): 349–54. http://dx.doi.org/10.15835/nsb739592.
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In order to study of diversity and classify agro-morphological characters under normal irrigation and drought stress in spring wheat cultivars, 20 cultivars were evaluated in the research farm of University of Tabriz, Iran. According to the results, significant correlation was found between grain yield and number of spikes per plant, number of tiller per plant, number of fertile tillers, spike length, root length, root number, root volume, root diameter and root dry weight under both conditions. Moreover, 1,000 grain weight and plant dry weight had significant positive correlation with grain yield under drought stress. Factor analysis detected four and two factors which explained 96.77% and 90.59% of the total variation in normal irrigation and drought stress conditions, respectively. In drought stress condition the first factor justified 69.52% of total variation and was identified as yield factor. The second factor explained 21.07% of total variation and represented the biomass and plant height factor. Cluster analysis was based on the four and two factors obtained. According to the amount of factors for clusters obtained under drought stress, ‘Kavir’, ‘Niknejhad’, ‘Moghan 3’, ‘Darya’ and ‘Marvdasht’ were identified as the most drought tolerant cultivars. Other cluster was comprised of ‘Bahar’, ‘Pishtaz’, ‘Bam’, ‘Sepahan’, ‘Sistan’, ‘Pars’ and ‘Sivand’ and was named as the most sensitive under drought stress. Tolerant cultivars identified within the study can be used for direct culture or as genitors in breeding programs.
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Abderamane Hamit, Mahamat Nour Abdallah, Moussa Abderamane e Mahamat Ahmat Sougoudji. "Hydrodynamic, hydrochemical and isotopic characterization of the waters of the quaternary aquifer of Bahr-El-Ghazal, north central Chad." World Journal of Advanced Research and Reviews 16, n.º 2 (30 de novembro de 2022): 794–803. http://dx.doi.org/10.30574/wjarr.2022.16.2.1147.
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Located in the middle of the Sahel, the study area is an integral part of the Bahr-El-Ghazal region. It is crossed by a fossil valley, which has a geological history similar to that of rivers that disappeared under the influence of climate change where evaporation phenomena were intense. From the hydrogeological point of view, the free water table of this region is housed in sedimentary geological formations of different natures. It passes from the sand tablecloth to that of the fluviolacustrine clays. In some cases, the latter confer particularly bad chemical qualities to the water, even though groundwater is the main source of drinking water for the local population. For this reason, a study aimed at understanding the different mechanisms that govern the chemical functioning of the aquifer of the Bahar-El-Ghazal region has been carried out. It is with this in mind that a piezometric study is being carried out in the first instance. This reveals the presence of some hydrodynamic anomalies. Thus, a shallow depth of the body of water is observed in the Harr and in the sandy formations of the extreme West. However, underground flows oriented from these two zones towards the central part characterize a deepening of the water level. Subsequently, a hydro-chemical study was undertaken. As regards the chemical facies, they also show an evolutionary character. They pass from calcium and magnesian bicarbonate facies to chloride or sodium and potassium sulphate facies in the piezometric depression. The values of the isotopic composition of the studied groundwater vary from -4.86 to 4.04‰ and -35.60 to 14.50‰ and delta 2H respectively.
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Nasamsir, Nasamsir, Yuza Defitri e Heri Suhermanto. "PROSES DEKOMPOSISI BATANG KELAPA SAWIT (Elaeis guineensis Jacq.) METODE REPLANTING SISIPAN DAN PENCINCANGAN". Jurnal Media Pertanian 2, n.º 2 (25 de outubro de 2017): 55. http://dx.doi.org/10.33087/jagro.v2i2.36.
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This research was carried out in Panca Mulya Village, Sungai Bahar District, Muaro Jambi Regency, Jambi Province since August to September 2017. The material that used was weathering stems of oil palm that already previously replanting by 6 to 7 months, while the tools that used was the Global Positioning System (GPS) with Garmin GPSmap 78s as its brand, plastic bag, holding tool, camera, and stationery. This research was carried out by survey methods applying. Samples was collected from the replanting areas of both underplanting and chipping method, respectively 2 blocks with 3 locations each block had 200 m distance to North direction with 0.2 kg weight. Secondary data was collected from a company and Indonesian Agency for Meteorological, Climatological and Geophysics (Badan Meteorologi, Klimatologi, dan Geofisika or simply BMKG) while primary data was an interviews with farmers using a questionnaire. The collected data were : general description of research location, rainfall, temperature, humidity, soil acidity, C-N ratio of oil palm stem both before and after decomposition, from the replanting of both underplanting and chipping methods. The result of this study showed that C-N ratio of oil palm stem before decomposition was 58.42, C-N ratio of oil palm stem decomposition that replanting with underplanting method was 37.18, and the average C-N ratio of chipping method was 14.24. Be equaling with the compost quality specifications on Indonesian national Standar (Standar Nasional Indonesia (SNI) 19-7030-2004, so C/N value of decomposition process of oil palm stem that replanting by chipping method was already meet this standard with 10 to 20 as a C/N grade. Keywords ; C-N ratio, oil palm, replanting methodPenelitian ini dilaksanakan di desa Panca Mulya, kecamatan Sungai Bahar, kabupaten Muaro Jambi, Jambi pada bulan Agustus sampai September 2017. Bahan yang digunakan adalah hasil pelapukan batang Kelapa sawit yang sudah direplanting 6 sampai 7 bulan sebelumnya, sedangkan alat-alat yang digunakan adalah Global Positioning System (GPS) merek Garmin GPSmap 78s, kantung plastik, alat pengambil bahan, kamera, dan alat tulis. Penelitian ini dilaksanakan dengan metode survey, sampel dikumpulkan dari areal replanting metode sisipan dan matode pencincangan, masing-masing 2 blok pada 3 titik setiap blok jarak 200 m arah utara dengan berat 0.2 kg. Data sekunder dikumpulkan dari perusahaan atau BMKG dan wawancara dengan petani menggunakan kuisioner. Data yang dikumpulkan adalah ; informasi umum lokasi penelitian, curah hujan, suhu, kelembaban, pH tanah, rasio C-N batang Kelapa sawit sebelum dekomposisi, serta rasio C-N hasil dekomposisi.dari replanting metode sisipan dan pencincangan. Hasil penlitian menunjukkan nisbah C-N batang Kelapa sawit di daerah penelitian sebelum dekomposisi 58,42, rasio C-N dekomposisi batang Kelapa sawit replanting dengan metode sisipan rata-rata 37.18, dan metode pencincangan rata-rata 14,24. Bila disetarakan dengan spesifikasi kualitas kompos SNI 19-7030-2004, nilai C/N proses dekomposisi batang Kelapa sawit hasil replanting metode pencincangan sudah memenuhi standar dengan nilai C/N 10 sampai 20.Kata kunci ; rasio C-N, Kelapa sawit, metode replanting
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Ahmad, Khadher, Mustaffa Abdullah, Sedek Ariffin e Mohd Yakub @Zulkifli Mohd Yusoff. "Fanatik Beragama dalam Kalangan Masyarakat Islam di Malaysia: Analisis Berdasarkan Pemahaman Terhadap Fiqh Al-Hadith". HADIS 7, n.º 14 (31 de dezembro de 2017): 39–74. http://dx.doi.org/10.53840/hadis.v7i14.26.
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In the Muslim community in Malaysia, mechanisms of religion can be seen in various atmosphere and conditions depending on the understanding of the teachings in the religion itself. Although Islam is derived from the Quran and guided by Prophet Muhammad Peace Be Upon Him, but in expressing understanding among the communities are different. Therefore, reveal different groups with different religious will be manifestation until the realization of the conditions that are simple, the fanatical (extreme) and the deviants. Through deductive and inductive analysis method, this article aims to collect the hadith associated with religious fanaticism and explain the meanings in the hadith refers to religious fanaticism and clarify understanding based on discussions base on fiqh al-hadith. The analysis found that there are five (5) hadith that form the basis of discussions related to the religious fanatics refer to the theory and the understanding aspect with three main themes: [1] the prohibition exceeds the limit, something extreme or burdensome; [2] ban invent a new religion and [3] religion that easy and not burdensome or charge.
ABSTRAK
Dalam masyarakat Islam di Malaysia, mekanisme beragama dapat dilihat dalam pelbagai suasana dan keadaan bergantung kepada pemahaman terhadap ajaran agama itu sendiri. Sekalipun agama Islam itu bersumberkan kepada al-Quran dan berpandukan kepada ajaran yang hanya dibawa oleh Nabi Muhammad SAW, tetapi dalam menzahirkan kefahaman dalam kalangan masyarakat adalah berbeza. Dari itu, lahirkan pelbagai golongan yang memanisfitasikan agama dengan pelbagai keadaaan sehingga wujudnya golongan yang bersifat sederhana, golongan yang fanatik (ekstrem) dan golongan yang sesat. Melalui metode analisis deduktif dan induktif, artikel ini bertujuan untuk mengumpulkan hadith berkaitan dengan fanatik beragama dan menjelaskan pengistilahan dalam hadith yang merujuk kepada fanatik beragama serta menjelaskan pemahaman berdasarkan perbincangan dalam fiqh al-Hadith. Hasil analisis mendapati bahawa terdapat lima (5) hadith yang menjadi asas perbincangan berkaitan dengan fanatik beragama dari sudut landasan teori dan pemahaman berkaitan dengannya dengan merujuk kepada tiga tema utama iaitu [1] larangan melampaui batas, extreme atau memberatkan sesuatu; [2] larangan mengada-adakan sesuatu baharu berkaitan agama dan [3] agama itu mudah dan tidak memberatkan atau membebankan.
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Sughra, Mariam, Farwa Fatima, Mouzma Marrium e Khizer Abbas. "Maternal health expenditures and health seeking behavior among lowest wealth quintile of the rural population in an under developed district of the Punjab, Pakistan". International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, n.º 7 (27 de junho de 2018): 2579. http://dx.doi.org/10.18203/2320-1770.ijrcog20182505.
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Background: Expenditures on maternal health is important factor to determine the health seeking behavior in pregnant women among the lowest economical section of Pakistan. This study was carried out determine the maternal health expenditures and health seeking behavior among lowest wealth quintile of rural Rahim Yar Khan.Methods: Sample Size: For this cross- sectional study, a total of 230 subjects were involved in the study from rural areas of Rahim Yar Khan including Basti Bahishti, Bah-o-Bahar and Chak 83/P. This study was comprised of duration of 06 months from 02/03/2016 to 04/09/2016. The head of Family (Husband) with monthly income less than 15000 Pakistani rupees (PKR) were included and marriage with in last 5 years with at alive delivery. While subjects having income more than 15000 PKR and not willing to participate in study were excluded from the study.Results: People with mean monthly income of PKR. 1176±4109 spent mean amount of PKR. 146442 ± 7747 on their marriages. While the mean expenses on treatment of complication in the last pregnancy were PKR. 35808±6771 and the amount saved for the treatment of complication was PKR. 2750±1157 only. Mean antenatal expenses were PKR. 1807±3335, Mean expenses on delivery were PKR. 7351±855 as compared to the money saved for delivery was PKR. 6115±1460. Mean expenses on complications during delivery were PKR. 1692±523. Mean expenses on postnatal care were PKR.8596±3597 while the mean amount used for treatment of postnatal complications were of PKR. 2451±560. Mean expenses on birth celebrations were of PKR. 7697±832.Conclusions: Present study reveals that there is a high financial cost of maternal health expenditures paid by the lowest wealth quintile in rural areas of Rahim Yar Khan when compared with the income of this quintile. Access of the people to the health sector is still limited due to low income of people, low health education and unavailability of health services in rural areas and even in 2017.
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Bahar, Furkan, Thomas C. Frost, Varsha Ananthapadmanabhan, Julia L. Schnabel, Manisha Thakuria e James A. DeCaprio. "Abstract 3042: Unraveling the mechanism of YAP toxicity in neuroendocrine solid tumors: Insights from Merkel cell carcinoma". Cancer Research 84, n.º 6_Supplement (22 de março de 2024): 3042. http://dx.doi.org/10.1158/1538-7445.am2024-3042.
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Abstract The Hippo pathway, a pivotal regulator orchestrating organ size and tissue growth, has emerged as a central player in cancer biology. The downstream transcription factor YAP within this pathway has been implicated in diverse oncogenic processes. YAP activation contributes to drug resistance, metastasis, and poor clinical outcomes in many solid tumors. Conversely, YAP exhibits growth-suppressive effects in neuroendocrine (NE) solid cancers, a paradox that remains poorly understood. Analysis of RNAseq data from the Cancer Cell Line Encyclopedia (CCLE) revealed a distinct classification of tumors into YAP1-expressing (YAPon) and non-expressing (YAPoff) subgroups, with hematopoietic malignancies and NE solid tumors featured prominently in the latter. Merkel cell carcinoma (MCC) is a rare, high-grade, NE carcinoma of the skin with two distinct etiologies. Virus-positive MCC contains integrated Merkel cell polyomavirus that expresses the viral T antigens and virus-negative MCC caused by sunlight exposure and extensive UV damage. Bulk RNAseq performed with more than 60 MCC tumors revealed that YAP expression displayed an inverse correlation with an NE gene expression signature. To gain insight into why YAP expression is so low in MCC, we generated MCC cell lines with inducible expression of YAP. Expression of YAP led to growth arrest and cell death. We performed a genome-wide CRISPR-Cas9 screen to identify genes that when lost enable MCC cells to tolerate YAP expression. Functional enrichment analysis of the positively selected genes uncovered a variety of signaling pathways. Intriguingly, the CRISPR screen revealed a positive enrichment of non-canonical BAF complex members, including BRD9 and SMARCD1. To validate this finding, we treated MKL-1 cells with a BRD9 inhibitor, observing a substantial reduction in YAP toxicity. These findings open avenues for the development of targeted therapeutic strategies for high grade NE cancers, addressing a critical gap in our understanding of YAP biology in the context of MCC and beyond. Citation Format: Furkan Bahar, Thomas C. Frost, Varsha Ananthapadmanabhan, Julia L. Schnabel, Manisha Thakuria, James A. DeCaprio. Unraveling the mechanism of YAP toxicity in neuroendocrine solid tumors: Insights from Merkel cell carcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 3042.
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Kraev, K., M. Geneva-Popova e S. Popova. "AB0489 CORRELATION BETWEEN DISEASE ACTIVITY AND SERUM TNF-ALPHA LEVELS IN PATIENTS WITH ANKYLOSING SPONDYLITIS". Annals of the Rheumatic Diseases 80, Suppl 1 (19 de maio de 2021): 1272.3–1272. http://dx.doi.org/10.1136/annrheumdis-2021-eular.931.
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Background:Ankylosing spondylitis (AS) is an immune-mediated rheumatic disease, it belongs to the spectrum of the axial spondyloarthritis. Several elements are important for the pathogenesis of AS - they include interactions in the context of a specific genetic origin between the intestinal microbiome, innate immunity, lymphoid cells and anatomical structures, which are the entheses of the axial skeleton and peripheral joints. The main mediators of the inflammatory process are TNF - α, IL-17 and IL-17A.Objectives:To study the level of TNF-alpha in the serum of patients with ankylosing spondylitis and to assess its relationship with the indices of disease activity before starting therapy with TNF-alpha blockers and in the dynamics after initiation of treatment.Methods:The present study included 50 patients with ankylosing spondylitis and 31 healthy controls similar in age, sex, and BMI. Clinical and non-clinical methods of examination and evaluation were used for proper assessment and follow-up of patients. The disease activity indices that were used were BASDAI and ASDAS. Statistical analysis was performed with the IBM SPSS program, v.24., To prove the relationship between the level of TNF-alpha in the serum of patients and disease activity, a correlation analysis of Spearman Rho was used.Results:The level of TNF-α in patients with AS was highest before treatment initiation with biologics, 89.77 ± 36.89 pg / ml, and was significantly higher than that of healthy controls. At the next visit, the TNF-α level decreased to 27.59 ± 23.88 pg / ml, the difference being significant from baseline. 24 months after initiation of treatment with biological therapy average level of TNF-α in patients with AS did not differ reliably from its levels in 6 and 12 month after initiation of treatment, respectively, 22.36 ± 22.38 pg/ml, 19,29 ± 21.07 pg/ml. The level of this cytokine significantly correlates with the activity of the disease, measured by the activity indices BASDAI, ASDAS.Conclusion:The level of the pro-inflammatory cytokine TNF-alpha is significantly higher in patients with ankylosing spondylitis and significantly correlates with the disease activity in them, measured by the respective indices (BASDAI, ASDAS).References:[1]Arends S., N. Lebbink, A. Spoorenberg et al., “The formation of autoantibodies and antibodies to TNF-α blocking agents in relation to clinical response in patients with ankylosing spondylitis”, Clin Exp Rheumatol, 2010, 28: 661- 668.[2]Bal A., E. Unlu, G. Bahar et al., “Comparison of serum IL-1 beta, sIL-2R, IL-6, and TNF-alpha levels with disease activity parameters in ankylosing spondylitis.” Clin Rheumatol, 2007, 26: 211–215.Disclosure of Interests:None declared.
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Lesley, Arthur M. "Abraham Melamed. On the Shoulders of Giants: The Debate between Moderns and Ancients in Medieval and Renaissance Jewish Thought. (‘Al kitfei ‘anaqim: Toldot ha-pulmus bein aharonim lerishonim bahagut ha-yehudit biyemei ha-beinayim uvreishit ha-’et ha-hadashah). Ramat-Gan: Bar Ilan University Press, 2003. 336 pp. index. bibl. $39. ISBN: 965-226-216-1." Renaissance Quarterly 59, n.º 4 (2006): 1267–69. http://dx.doi.org/10.1353/ren.2008.0520.
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ASMA, Bülent, Süreyya YİĞİTALP RENÇBER, Sinemis ÇETİN DAĞLI e Ali CEYLAN. "HEALTHY LIFE-STYLE BEHAVIOURS AND EFFECTING FACTORS OF FINAL YEAR STUDENTS ATTENDING TO TWO DIFFERENT MEDICINE FACULTIES". International Journal of Health Services Research and Policy 4, n.º 1 (1 de abril de 2019): 11–21. http://dx.doi.org/10.33457/ijhsrp.525434.
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This study was carried out to determine and compare the Lifestyles of final year medicine faculty students attending two different universities.The population of this descriptive type study consists of final year students attending Dicle University Medicine Faculty (DUMF) and Van Yüzüncüyıl University Medicine Faculty (YYUMF). In 2018-2019 academic year, 166 and 84 intern students are attending to DUMF and YYUMF, respectively; hence, through this number, it is aimed to reach all population. In DUMF, 160 and in YYUMF, 62 were contacted. The students were informed; and they confirmed the consent form and a questionnaire containing descriptive information arranged by Walker. Turkish validity and reliability survey, Healthy Lifestyle Behavioural Scale, was carried out by Bahar et al. in 2008; and the students were given “Healthy Lifestyle Behavioural Scale II” (HLSBS-II), and they were asked to respond the questionsThe mean of total scores of HLSBS in DUMF students is 127,85±19,1, while it is 121,42±18,7 in YYUMF students (p=0,04). According to sub groups of HLSBS, the scores that the students gained are as follows: The mean in health responsibility total score of DUMF students is 21,05±4,9, while it is 19,08±4,2 in YYUMF students(p=0,007). The mean in physical activity total score of DUMF students is 16,42±4,9, while it is 17,54±4,6 in YYUMF students (p=0,123). The mean in nourishment total score of DUMF students is 19,08±4,4, while it is 18,80±3,5 in YYUMF students (p=0665). The mean in spiritual development of DUMF students is 26,3±4,5, while it is 24,43±5,8 in YYUMF students (p=0,027). The mean in interpersonal relations of DUMF students is 24,94±4,5, while it is 23,10±3,6 in YYUMF students (p=0,005). The mean in stress management of DUMF students is 19,97±3,6, while it is 19,39±4,5 in YYUMF students (p=0,370). Total HLSBS score of the students whose family income is good is 130,85±17,5, while the total HLSBS score of the ones whose family income is bad is 113,76±18,8(p=0,004). While the total score of physical activity according gender is 17,52±4,9 for men which is higher than women with 15,39±3,8 (p=0,001), inter individual relation total point is higher with women (25,3±4,5) than man (23,91±4,2) (p=0,001). The fact that the medicine faculty students should lead healthy lifestyle behaviour is important due to the fact that they make a role model for not only themselves but for the society as well. It is thought-provoking that while in normal circumstances 204 score can be obtained from the scale, medicine faculty intern students have received an average of 127,85 score in HLSBS-II; and while in normal condition, it is possible to get 32 scores in the physical activity sub group; medicine students have received only 16,42 score. In order to make the individuals adopt healthy Lifestyle, the earlier the individuals are provided with education and opportunities, the healthier they will be.
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Wang, Zhongyang, Ge Sun, Mrinmay Mandal, Paul Kohl, Juan de Pablo, Shrayesh N. Patel e Paul F. Nealey. "Role of Water Molecules in Enabling Site Hopping and Vehicular Transport Mechanisms in Polynorbornene-Based Anion Exchange Membrane". ECS Meeting Abstracts MA2022-02, n.º 41 (9 de outubro de 2022): 1536. http://dx.doi.org/10.1149/ma2022-02411536mtgabs.
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Role of Water Molecules in Enabling Site Hopping and Vehicular Transport Mechanisms in Polynorbornene-based Anion Exchange Membrane Zhongyang Wang, ⸹ Ge Sun ， ⸹ Mrinmay Mandal, ‡, Paul A. Kohl, ‡, Juan de Pablo, ⸹ Shrayesh N. Patel, ⸹ and Paul F. Nealey ⸹ ‡ School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia, 30332-0100, United States ⸹ Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, USA Ion exchange membranes are at the heart of electrochemical conversion and storage devices such as fuel cells 1, water electrolyzers 2, CO2 electrolyzers 3. redox flow batteries 4, and reverse electrodialysis 5. Anion exchange membrane fuel cells (AEMFCs) have attracted enormous attention as alternatives to replace perfluorinated, sulfonic acid-based proton exchange membrane fuel cells (PEMFCs) 6 because alkaline membrane electrode assemblies (MEAs) composed of anion exchange ionomers (AEIs) and AEMs that allow the use of Ni 7, 8, Fe 9, and Ag 10 based precious-group-metal (PGM) free catalysts in alkaline environments for hydrogen oxidation reactions (HORs) and oxygen reduction reactions (ORRs). However, the lack of understanding of ion transport mechanisms at different hydration levels of an anion exchange membrane hinders the rational design of the MEAs in an AEMFC. Here we investigate site hopping and vehicular transport mechanisms using anion exchange thin films, interdigitated electrodes, and atomistic molecular dynamics simulations. Halide ion (Br-, Cl- and I-) conductivities in polynorbornene-based thin films are measured as a function of temperature and relative humidity using electrochemical impedance spectroscopy. Halide ions show Arrhenius behaviors, and activation energy (Ea) is for the first time used as an indicator for detecting the transition of site hopping and vehicular transport mechanisms. Using atomistic molecular dynamics simulation, we quantitatively demonstrate that the transition of site hopping and vehicular mechanisms is aided by better solvation environments of anions and more percolated water pathways. References Z. Wang, J. Parrondo, C. He, S. Sankarasubramanian and V. Ramani, Nature Energy, 2019, 4, 281-289. S. Z. Oener, M. J. Foster and S. W. Boettcher, Science, 2020, 369, 1099-1103. D. A. Salvatore, C. M. Gabardo, A. Reyes, C. P. O’Brien, S. Holdcroft, P. Pintauro, B. Bahar, M. Hickner, C. Bae, D. Sinton, E. H. Sargent and C. P. Berlinguette, Nature Energy, 2021, 6, 339-348. K. Lin, Q. Chen, M. R. Gerhardt, L. Tong, S. B. Kim, L. Eisenach, A. W. Valle, D. Hardee, R. G. Gordon, M. J. Aziz and M. P. Marshak, Science, 2015, 349, 1529-1532. R. D. Cusick, Y. Kim and B. E. Logan, Science, 2012, 335, 1474-1477. J. Wang, Y. Zhao, B. P. Setzler, S. Rojas-Carbonell, C. Ben Yehuda, A. Amel, M. Page, L. Wang, K. Hu, L. Shi, S. Gottesfeld, B. Xu and Y. Yan, Nature Energy, 2019, 4, 392-398. G. Braesch, Z. Wang, S. Sankarasubramanian, A. G. Oshchepkov, A. Bonnefont, E. R. Savinova, V. Ramani and M. Chatenet, Journal of Materials Chemistry A, 2020, 8, 20543-20552. S. Kabir, K. Lemire, K. Artyushkova, A. Roy, M. Odgaard, D. Schlueter, A. Oshchepkov, A. Bonnefont, E. Savinova, D. C. Sabarirajan, P. Mandal, E. J. Crumlin, Iryna V. Zenyuk, P. Atanassov and A. Serov, Journal of Materials Chemistry A, 2017, 5, 24433-24443. H. Adabi, A. Shakouri, N. Ul Hassan, J. R. Varcoe, B. Zulevi, A. Serov, J. R. Regalbuto and W. E. Mustain, Nature Energy, 2021, 6, 834-843. H. Erikson, A. Sarapuu and K. Tammeveski, ChemElectroChem, 2019, 6, 73-86.
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Wheeler, Caroline, Yuanquan Yang, Daniel Spakowicz, Rebecca Hoyd e Mingjia Li. "942 The tumor microbiome correlates with response to immune checkpoint inhibitors in renal cell carcinoma". Journal for ImmunoTherapy of Cancer 9, Suppl 2 (novembro de 2021): A988—A989. http://dx.doi.org/10.1136/jitc-2021-sitc2021.942.
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BackgroundImmune checkpoint inhibitor therapy, or ICI, is currently the most successful treatment option for patients with renal cell carcinoma (RCC). However, only 20% of patients have a durable response,1 driving a significant need to improve treatment outcomes. The tumor microbiome has recently been shown to play a role in chemotherapy-based treatment outcomes, but, to our knowledge, no study has explored its role in response to ICIs.2–4MethodsTumor samples were collected from 22 patients with RCC as a part of the Total Cancer Care program at The Ohio State University Comprehensive Cancer Center. Raw RNA-seq reads from these biopsies, as well as data on the responses to ICI therapy were collected. Response evaluation was based on RECIST v1.1 criteria with complete or partial response, or stable disease classified as ”Responders,”, and progressive disease classified as ”Non-responsders”. The RNA-seq reads were processed through a pipeline developed by the Spakowicz lab, known as ExoTIC (Exogenous sequences in Tumor and Immune Cells), to carefully identify exogenous sequences.5 6 Reads that don’t align to the human reference genome are meticulously filtered of (1) common laboratory contaminants, (2) taxa that inversely correlate with input RNA quantity, and (3) taxa commonly found in the negative controls of microbiome experiments. DESeq2 was used to perform a differential abundance analysis on the comparison groups at every taxonomic level.ResultsThe 22 patients with RCC range from 22 to 74 years of age at diagnosis, are 72.7% male, and 54.5% responded to ICIs. Exogenous taxa are identified in the tumor RNAseq, including bacteria, fungi, and viruses (figure 1). Within the tumors responsive to immunotherapy, there was found to be a significant enrichment of certain microbial species, including Bacillus thuringiensis, Comamonas testosteroni, Colletotrichum higginsianum, and Elaeis guineesis. Comparatively, the cohort of non-responsive tumors was found to have a significant enrichment of Candidatus Promineofilum breve, Clostridioides difficile, Nocardia cyriacigeorgica, Streptomyces sp. CdTB01, and Streptomyces venezuelae (figure 2).Abstact 942 Figure 1Relative abundances of exogenous taxa found in tumor RNAseq are shown in a stacked bar plotAbstact 942 Figure 2Differential abundance analysis of taxa found within tumor RNAseq data by the exotic pipeline. Colored points represent significantly (pvalue < 0.05) enriched taxa with a high (>2.5) fold-difference in abundance between the groupsConclusionsWe found that prior to ICI treatment the tumor microbiome of patients with RCC whose tumors responded to immunotherapy vary from those that did not respond to treatment. This implies that a therapeutic target to modify the tumor microbiome to improve treatment outcomes. Future research will evaluate whether these correlations are causally associated with outcomes and will evaluate their effect on the tumor microenvironment including immune cell infiltration.AcknowledgementsThe authors acknowledge the support and resources of the Ohio Supercomputing Center (PAS1695).ReferencesCiccarese C, Di Nunno V, Iacovelli R, Massari F. Future perspectives for personalized immunotherapy in renal cell carcinoma. Expert opinion on biological therapy. Taylor & Francis. 2017;17(9):1049–1052.Geller LT, Barzily-Rokni M, Danino T, Jonas OH, Shental N, Nejman D, Gavert N, Zwang Y, Cooper ZA, Shee K, Thaiss CA, Reuben A, Livny J, Avraham R, Frederick DT, Ligorio M, Chatman K, Johnston SE, Mosher CM, Brandis A, Fuks G, Gurbatri C, Gopalakrishnan V, Kim M, Hurd MW, Katz M, Fleming J, Maitra A, Smith DA, Skalak M, Bu J, Michaud M, Trauger SA, Barshack I, Golan T, Sandbank J, Flaherty KT, Mandinova A, Garrett WS, Thayer SP, Ferrone CR, Huttenhower C, Bhatia SN, Gevers D, Wargo JA, Golub TR, Straussman R. Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine. Science 2017 September 15;357(6356):1156–1160. PMID: 28912244.Nejman D, Livyatan I, Fuks G, Gavert N, Zwang Y, Geller LT, Rotter-Maskowitz A, Weiser R, Mallel G, Gigi E, Meltser A, Douglas GM, Kamer I, Gopalakrishnan V, Dadosh T, Levin-Zaidman S, Avnet S, Atlan T, Cooper ZA, Arora R, Cogdill AP, Khan MAW, Ologun G, Bussi Y, Weinberger A, Lotan-Pompan M, Golani O, Perry G, Rokah M, Bahar-Shany K, Rozeman EA, Blank CU, Ronai A, Shaoul R, Amit A, Dorf-man T, Kremer R, Cohen ZR, Harnof S, Siegal T, Yehuda-Shnaidman E, Gal-Yam EN, Shapira H, Baldini N, Langille MGI, Ben-Nun A, Kaufman B, Nissan A, Golan T, Dadiani M, Levanon K, Bar J, Yust-Katz S, Barshack I, Peeper DS, Raz DJ, Segal E, Wargo JA, Sandbank J, Shental N, Straussman R. The human tumor microbiome is composed of tumor type–specific intracellular bacteria. Science 2020 May 29;368(6494):973–980.Poore GD, Kopylova E, Zhu Q, Carpenter C, Fraraccio S, Wandro S, Kosciolek T, Janssen S, Metcalf J, Song SJ, Kanbar J, Miller-Montgomery S, Heaton R, Mckay R, Patel SP, Swafford AD, Knight R. Microbi-ome analyses of blood and tissues suggest cancer diagnostic approach. Nature 2020;579(7800):567–574. PMID: 32214244.Malalur, Pannaga, Mo, Xiaokui, Hoyd, Rebecca, Hays, John, Carbone, David, Spakowicz, Daniel. Investigating intra-tumor microbes, blood microbes, and CEA for development of non-invasive biomarkers in colorectal cancer. Journal of Clinical Oncology 2021;39(15_suppl): 3551–3551.Malalur PG, Mo X, Hoyd R, Carbone DP, Spakowicz D. Intra-tumoral microbes and overall survival in colorectal cancer patients. Journal of Clinical Oncology 2020;38(15_suppl):4083–4083.Ethics ApprovalData were obtained through an IRB-approved Honest Broker protocol (2015H0185) supporting the Total Cancer Care protocol 2013H0199.
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Gado, Alanna M., Deniz Ipekçi, Stoyan Bliznakov, Leonard J. Bonville, Jeffrey McCutcheon e Radenka Maric. "Investigation of the Performance and Durability of Reactive Spray Deposition Fabricated Electrodes on a Bifunctional Membrane for Alkaline Water Electrolysis and CO2 Reduction Reaction". ECS Meeting Abstracts MA2023-01, n.º 38 (28 de agosto de 2023): 2250. http://dx.doi.org/10.1149/ma2023-01382250mtgabs.
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Alkaline water electrolysis (AWE) is a promising technology for carbon capture [1]. Anion exchange membrane water electrolyzers (AEMWEs) utilize low-cost, non-precious metal materials, providing an economically viable alternative to more expensive proton exchange membrane water electrolyzers (PEMWEs). While PEMWEs can operate at much higher current densities, they require noble metal catalysts and titanium components for the high potential environment anode [1]. The implementation of a bipolar membrane (BPM) will allow both HER and OER to occur under kinetically favorable conditions [2, 3] by combining both thin AEM and thin PEM layers within a single membrane. AEMs, PEMs, and BPMs have been tested in CO2RR electrolyzers [4]. The BPM may provide a pathway to combine the advantages of both AEMs and PEMs for CO2 reduction. Altering both the membrane and CCM is a focus in the research and development in CO2RR electrolyzers. Lee et al. [5] explored the use of a porous membrane for CO2 reduction. While work can be done to improve performance and crossover, the porous membrane provided excellent mechanical properties and good economic potential. There has been some work done on developing bifunctional membranes for water electrolysis and CO2 reduction [3, 6, 7]. Two key issues with operation of a CO2RR electrolyzer with a BPM is the reactant CO2 that is lost to the AEM and PEM membrane layer interface and the instability of the cell. Both issues contribute to a significant decrease in performance and faradaic efficiency in product conversion. Development of the BPM, both on the membrane’s fabrication and configuration, and electrode layers, needs to be explored to reach higher performances and longer lifespans. In this work, reactive spray deposition technology (RSDT) was used to fabricate electrodes on a UConn fabricated bipolar membrane. Testing of each configuration was conducted as both an AEM water electrolyzer and CO2RR electrolyzer. Polarization, electrochemical impedance spectroscopy, electrochemical equivalent circuits, and distribution of relaxation times were used to investigate cell performance and durability. References [1] B. Mayerhofer, D. McLaughlin, T. Bohm, M. Hegelheimer, D. Seeberger, and S. Thiele, “Bipolar membrane electrode assemblies for water electrolysis,” ACS applied energy materials, vol. 3, no. 10, pp. 9635–9644, 2020. [2] J. Xu, I. Amorim, Y. Li, J. Li, Z. Yu, B. Zhang, A. Araujo, N. Zhang, and L. Liu, “Stable overall water splitting in an asymmetric acid/alkaline electrolyzer comprising a bipolar membrane sandwiched by bifunctional cobalt-nickel phosphide nanowire electrodes,” Carbon Energy, vol. 2, no. 4, pp. 646–655, 2020. [3] Q. Lei, B. Wang, P. Wang, and S. Liu, “Hydrogen generation with acid/alkaline amphoteric water electrolysis,” Journal of Energy Chemistry, vol. 38, pp. 162–169, 2019. [13] W. H. Lee, K. Kim, C. Lim, Y. J. Ko, Y. J. Hwang, B. K. Min, U. Lee, and H. S. Oh, “New strategies for economically feasible CO2 electroreduction using a porous membrane in zero-gap configuration,” Journal of Materials Chemistry A, vol. 9, pp. 16169–16177, 8 2021 [4] D. A. Salvatore, C. M. Gabardo, A. Reyes, C. P. O’Brien, S. Holdcroft, P. Pintauro, B. Bahar, M. Hickner, C. Bae, D. Sinton, E. H. Sargent, and C. P. Berlinguette, “Designing anion exchange membranes forCO2 electrolysers,” Nature Energy, vol. 6, pp. 339–348, 4 202 [5] W. H. Lee, K. Kim, C. Lim, Y. J. Ko, Y. J. Hwang, B. K. Min, U. Lee, and H. S. Oh, “New strategies for economically feasible CO2 electroreduction using a porous membrane in zero-gap configuration,” Journal of Materials Chemistry A, vol. 9, pp. 16169–16177, 8 2021 [6] W. Li, Z. Yin, Z. Gao, G. Wang, Z. Li, F. Wei, X. Wei, H. Peng, X. Hu, L. Xiao, J. Lu, and L. Zhuang, “Bifunctional ionomers for efficient CO electrolysis of CO2 and pure water towards ethylene production at industrialscale current densities,” Nature Energy, 2022 [7] C. P. O’Brien, R. K. Miao, S. Liu, Y. Xu, G. Lee, A. Robb, J. E. Huang, K. Xie, K. Bertens, C. M. Gabardo, et al., “Single pass CO2 conversion exceeding 85% in the electrosynthesis of multicarbon products via local CO2 regeneration,” ACS Energy Letters, vol. 6, no. 8, pp. 2952–2959, 2021.
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Mansir, Firman, Sofyan Abas e Lia Kian. "SARANA DAN METODE PEMBELAJARAN EFEKTIF PESERTA DIDIK DI SEKOLAH DASAR ERA DIGITAL". Taman Cendekia: Jurnal Pendidikan Ke-SD-an 5, n.º 2 (29 de dezembro de 2021): 619–29. http://dx.doi.org/10.30738/tc.v5i2.11347.
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The purpose of writing this article was to find out and explain effective learning methods used and applied in elementary schools in the digital era. In addition, this study could review the lack of utilization and management of facilities in elementary schools. At the time of starting their age, the students needed to get guidance by using a way that was in sync with the situation they were experiencing. Methods that could be used for education were advice, stories, and customs. There were no bad or good methods. Because it depended on many factors. The crucial thing that educators paid attention to in deciding a method was to know the limits of the goodness and weaknesses of the method to be used. As a result, it was possible to formulate conclusions regarding the outcome or achievement of tnegrihe decision objectives. The use of facilities was very crucial for the continuity of the teaching and learning process and increasing the quality of learning for students and educators. The facilities greatly hypnotized the ability of students to learn. This showed that the role of facilities was very crucial in supporting the quality of student learning. Management of facilities was a very crucial activity in schools, the success of learning in schools lied in how the strategic location of schools was placed. This study used a qualitative approach, so that in conducting data analysis the literature analysis method was sourced from various data that had been prepared. Keywords: method, learning, student. References: Anugraheni, I. 2018. Meta Analisis Model Pembelajaran Problem Based Learning dalam Meningkatkan Keterampilan Berpikir Kritis di Sekolah Dasar [A Meta-analysis of Problem-Based Learning Models in Increasing Critical Thinking Skills in Elementary Schools]. Polyglot: Jurnal Ilmiah, 14(1), 9–18. Baharun, H., & Finori, F.D. 2019. Smart Techno Parenting: Alternatif Pendidikan Anak Pada Era Teknologi Digital. Jurnal Tatsqif, 17(1), 52–69. Deshler, D.D., Schumaker, J. B., Lenz, B. K., Bulgren, J. A., Hock, M. F., Knight, J., & Ehren, B. J. 2001. Ensuring content‐area learning by secondary students with learning disabilities. Learning Disabilities Research & Practice, 16(2), 96–108. Gull, F., & Shehzad, S. 2015. Effects of cooperative learning on students’ academic achievement. Journal of Education and Learning, 9(3), 246–255. Hadi, S. 2011. Pembelajaran Sosial Emosional Sebagai Dasar Pendidikan Karakter Anak Usia Dini. Jurnal Teknodik, 15(2), 227–240. Jannah, S. N., & Sontani, U. T. 2018. Sarana dan prasarana pembelajaran sebagai faktor determinan terhadap motivasi belajar siswa. Jurnal Pendidikan Manajemen Perkantoran (JPManper), 3(1), 63–70. Mansir, F. 2020. Identitas Guru PAI Abad 21 Yang Ideal pada Pembelajaran Fiqh di Sekolah dan Madrasah. Muslim Heritage, 5(2), 435. Mansir, F. 2020. Kesejahteraan Dan Kualitas Guru Sebagai Ujung Tombak Pendidikan Nasional Era Digital. Jurnal IKA PGSD (Ikatan Alumni PGSD) UNARS, 8(2), 293–303. Mansir, F. 2020. Management of Fiqh Learning In School an Madrasah For Islamic Religious Education Teacher. Ta’dib: Jurnal Pendidikan Islam, 9(2), 78–85. Mansir, F. 2020. Manajemen Pondok Pesantren di Indonesia dalam Perspektif Pendidikan Islam Era Modern. QALAMUNA: Jurnal Pendidikan, Sosial, Dan Agama, 12(2), 207–216. Mansir, F. 2020. The impact of globalization on islamic education toward fiqh learning existence in covid-19 pandemic period. ATTARBIYAH: Journal of Islamic Culture and Education, 5(2), 123–133. Mansir, F. 2020. The Urgency of Fiqh Siyasah In Islamic Education Learning At Madrasas And Schools. POTENSIA: Jurnal Kependidikan Islam, 6(2), 142–154. Mansir, F. 2020. Urgensi Metode Ceramah dan Diskusi (Buzz Group) dalam Proses Pembelajaran di Madrasah. TADRIS: Jurnal Pendidikan Islam, 15(2), 225–235. Mansir, F. 2021. Aktualisasi Pendidikan Agama dan Sains dalam Character Building Peserta Didik di Sekolah dan Madrasah. J-PAI: Jurnal Pendidikan Agama Islam, 7(2). Mansir, F. 2021. Analisis model-model pembelajaran fikih yang aktual dalam merespons isu sosial di sekolah dan madrasah. Ta’dibuna: Jurnal Pendidikan Islam, 10(1), 88–99. Mansir, F. 2021. Kontribusi Kepemimpinan Kepala Sekolah Dalam Mewujudkan Pendidikan Humanis. TADBIR MUWAHHID, 5(2), 149–166. Mansir, F. 2021. Paradigma Pendidikan Inklusi Dalam Perspektif Pendidikan Islam: Dinamika Pada Sekolah Islam. Tadrib, 7(1), 1–17. Mansir, F. 2021. The Urgency of Fiqh Education and Family Role in The Middle of Covid-19 Pandemic For Students In School and Madrasah. Kamaya: Jurnal Ilmu Agama, 4(1), 1–10. Mansir, F., Parinduri, M. A., & Abas, S. 2020. Implementasi Pendidikan Karakter Melalui Kegiatan Pembinaan Peserta Didik Dalam Membentuk Watak Kuat-Positif. Taman Cendekia: Jurnal Pendidikan Ke-SD-An, 4(1), 429–437. Masturdin, M. 2016. Kreativitas Guru Menumbuhkan Motivasi Belajar Siswa dalam Upaya Peningkatan Hasil Belajar Aqidah Akhlak di MTSN Rukoh Darussalam Banda Aceh. PIONIR: Jurnal Pendidikan, 5(2). Prastyawan, P. 2016. Manajemen Sarana dan Prasarana Pendidikan. Al Hikmah: Jurnal Studi Keislaman, 6(1). Rianie, N. 2015. Pendekatan dan Metode Pendidikan Islam (sebuah perbandingan dalam konsep teori pendidikan Islam dan barat). Management of Education, 1(2). Sadeghi, R., Sedaghat, M. M., & Ahmadi, F. S. 2014. Comparison of the effect of lecture and blended teaching methods on students’ learning and satisfaction. Journal of Advances in Medical Education & Professionalism, 2(4), 146. ShahsavariIsfahani, S., Mosallanejad, L., & Sobhanian, S. 2010. The effect of virtual and traditional methods on students learning and competency–based skills. Hormozgan Medical Journal, 14(3), 184–190. Ummah, M. S. (n.d.). Manajemen Strategi Program Pendidikan Diniyah dalam Pembentukan Karakter Siswa di SMP Negeri 2 Jombang Kabupaten Jombang. Jurnal Meirinawati. 13–28. Yamin, M. 2015. Teori dan Metode Pembelajaran: Konsepsi, Strategi dan Praktik Belajar yang Membangun Karakter. Malang: Madani. Kelompok Intrans Publishing) Anggota IKAPI.
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Mishra, KP. "Remembering Dr. Bam Bahadur Singh: An outstanding Scientist and a learned lawyer". Journal of Radiation and Cancer Research, 2023, 0. http://dx.doi.org/10.4103/jrcr.jrcr_9_23.
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Scott, Jason M., Joshua L. Jackson e Andrea M. Pals. "Are Law Schools Cream-Skimming to Bolster Their Bar Exam Pass Rates? A Multilevel Regression Approach to Estimate How Attrition and Transfer Rates Affect Bar Passage". AERA Open 10 (janeiro de 2024). http://dx.doi.org/10.1177/23328584231214526.
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Law schools are held accountable on many fronts to achieve and maintain high bar passage rates. While the course of legal education itself, along with various interventions, is a key driver of bar exam performance, Bahadur et al. (2021) suggests that obscure institutional practices might be inflating institutional bar passage performance. Such practices could include recruitment and admission of transfer students and academic attrition. We examine this hypothesis to assess the influence of both attrition and transfer on law schools’ bar passage differential using fixed-effects and between-within models. We also utilize Poisson regression to explore the effect of geographical proximity to other law schools on transfer rates. We find that, on average, neither attrition nor transfer activity substantively affect bar passage performance, and that although geographic proximity to other schools is related to transfer rates, this relationship does not result in notable differences in bar passage.
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SEZER, Ayşe. "ŞECERE-İ TERÂKİME’YE PSİKOSOYBİLİM BAĞLAMINDA BİR YAKLAŞIM". Motif Akademi Halk Bilimi Dergisi, 1 de dezembro de 2022. http://dx.doi.org/10.12981/mahder.1191452.
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Ebulgâzi Bahadır Han, 1603-1663 yılları arasında, Türkistan hanlıklarının çalkantılı dönemlerinde yaşamış, Çingiz soyundan gelerek yirmi bir yıl Hive hanlığı yapmış bir Türk hükümdarıdır. Ebulgâzi Bahadır Han’ın bizim için asıl önemi, Türklerdeki Oğuznamecilik geleneği adı altında iki önemli şecerenameyi/Oğuzname’yi kaleme almasıdır. Bunlardan ilki olan Şecere-i Terâkime 1660’ta kaleme alınmış; Şecere-i Türk ise 1663 yılında Ebulgâzi’nin ölümü üzerine yarım kalmış ve oğlu tarafından tamamlanmıştır. Şecere-i Terâkime’nin kaynağını büyük oranda Reşidüddin’in Câmiü’t Tevârih’indeki Farsça Oğuzname ile Türkmenler arasından toplanan yirmi kadar rivayet oluşturmaktadır. Bu toplanan rivayetler tarihe ve folklora kaynaklık etmekle beraber, soyun/genin psikolojik boyutta yorumlanmasına da olanak sağlar. Psikosoybilim, Anne Ancelin Schützenberger’in uzun ve titiz çalışmaları sonucunda oluşturulan; olumlu ya da olumsuz psikolojik meselelerin kaynağını kendi hayatında bulamayan bireylerin geçmişini araştıran; kuşaklar boyunca tekrar eden travmaların gün yüzüne çıkarılmasını sağlayan klinik bir yöntemdir. Aynı zamanda bu yöntem, ruhsal mirasımızı anlamamıza ve kuşaklararası bağlantıları içine alan zengin şecere bilgilerini algılamamıza, kendi içinde oluşturduğu tekniklerle yardım etmektedir. Bu çalışmada, zengin bir şecerecilik geleneği oluşturan Türklerin, bu şecereleri/Oğuznameleri ne maksatla kaleme aldıkları, ardından da bu şecerelerdeki birçok unsurun ne anlama geldiği psikolojik bağlamda incelenmeye çalışılmıştır. Çalışmada, Türk toplumundaki Oğuznamecilik geleneği ve şecere kültürünün, Şecere-i Terâkime adlı eser baz alınarak psikosoybilimsel yöntem bağlamında yorumlanması amaçlanmıştır. Şecere-i Terâkime’de, eserin yazılış amacı ve soyun teker teker açıklanmasının, tarihin psikolojik biçimde yorumlanmasına olanak sağladığı görülmüştür. Şecere-i Terâkime’nin iyi ya da kötü birçok olayın tekrar gözden geçirilmesi ve kişiler arasındaki bağların bulunması açısından fazlasıyla yoruma açık olduğu tespit edilmiştir.
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DOĞAN, Süleyman. "Yükseköğretim Öğrencilerinin Mevlana Celaleddin Rumi’ye Yazdıkları 100 Mektubun Tematik İncelenmesi". Bingöl Araştırmaları Dergisi, 11 de outubro de 2022. http://dx.doi.org/10.53440/bad.1162214.
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Bu çalışmada, yükseköğretim (üniversite) öğrencilerinin “Mevlana Celaleddin Rumi’ye Açık Mektup” şeklinde yazdıkları 100 mektup incelenerek, O’nun hakkında neler bilip bilmediklerinin belirlenmesi hedeflenmiştir. Yıldız Teknik Üniversitesi’nde “2021 Bahar” döneminde katılımcı öğrencilerden “Mevlana Celaleddin Rumi’ye Açık Mektup” yazmaları istenmiştir. Çalışma, araştırmacının seçmeli ders verdiği katılımcı öğrencilerin, her fakülteden, her birimden, her sınıf düzeyinde, her branştan, her bölümden, 18-25 yaş aralığında kız ve erkek öğrencilerden oluşmaktadır. Dört ayrı sınıfta 180 lisans öğrencisinin 160’ı “Mevlana Celaleddin Rumi’ye Açık Mektup” başlığında mektup yazmışlardır. İçlerinden rastgele 100 mektup incelenmiş ve içerik analizine tabi tutulmuştur. Bu çalışma, üniversitenin neredeyse tamamını içine alan küçük bir nüveyi ve ortalama bir örneklemi teşkil etmektedir. Mektuplarda açıkça görülmektedir ki, kişiler ve mektupların sayısı kadar farklı olmakla birlikte özünde Mevlana Celaleddin Rumi’yi bildikleri ve onu çok sevdikleri ortaya çıkmıştır. Araştırma sonucunda; katılımcı öğrencilerin Mevlana Celaleddin Rumi’ye karşı büyük bir saygı ve sevgi besledikleri saptanmıştır. Katılımcıların Mevlana Celaleddin Rumi ile sevgi sözcüğünü birlikte kullandıkları belirlenmiştir. Onun örnek ve model biri olduğu öğrenciler tarafından mektuplarda vurgulanmıştır. Katılımcı öğrencilerin Mevlana Celaleddin Rumi’nin önemli marka şahsiyet olduğu konusunda fikir birliği ettikleri bulgusuna ulaşılmıştır.
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Alam, Laima, Jawad Khan, Mafaza Alam, Varqa Faraid, Fahad Ajmal e Laila Bahadur. "Residents’ perspective on the quality of postgraduate training programs in Pakistan – the good, the bad and the ugly". Pakistan Journal of Medical Sciences 37, n.º 7 (8 de setembro de 2021). http://dx.doi.org/10.12669/pjms.37.7.4297.
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Objectives: To assess the satisfaction of trainees towards different attributes of their training programs.
Methods: This cross-sectional survey was carried out by enrolling trainee doctors currently working in Medical, Surgical, Dental and Allied specialties of the country by sending a validated and piloted questionnaire through email. Data collection was done from 1st to 31st January 2021 after taking ethical approval from the concerned authorities. Data was analysed using SPSS v. 19.0.
Results: A total of 516 completed responses were received from 15 major cities of the country. The overall perceived satisfaction towards clinical skills (42%), teaching skills (31.4%), personal growth and development (23.6%), research (21%) and supervisor’s role (44.2%) were considerably low with the most common causes for non-satisfaction being poor work-life balance (59%), financial instability (54.5%), poor research facilities (53%), poor career guidance (44%) and poor skill development (42.4%) in descending order. Senior years of residency, government and private set-ups, less than four and greater than 13 residents on average with less than three supervisors per department, excessive duty hours and financial instability in-lieu of not doing locums were statistically related to poor satisfaction across majority of the facets of residency as well the overall satisfaction towards training programs.
Conclusion: There is a tremendous scope for improvement in the recognized and partially acknowledged attributes of our training programs. Yearly feedback surveys involving residents is essential for enlightening the authorities and mitigating the trainees’ grievances.
doi: https://doi.org/10.12669/pjms.37.7.4297
How to cite this:Alam L, Khan J, Alam M, Faraid V, Ajmal F, Bahadur L. Residents’ perspective on the quality of postgraduate training programs in Pakistan – the good, the bad and the ugly. Pak J Med Sci. 2021;37(7):---------. doi: https://doi.org/10.12669/pjms.37.7.4297
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Othman, Siti Suriani, e Lee Kuok Tiung. "Pemilihan peristiwa dalam proses pemberitaan". Jurnal Komunikasi Borneo (JKoB), 22 de setembro de 2020, 95–105. http://dx.doi.org/10.51200/jkob.vi.2616.
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Kajian-kajian berkenaan penghasilan berita menawarkan pelbagai penjelasan tentang mengapa berita boleh bertukar menjadi apa yang dipaparkan (Berkowitz, 1988). Namun begitu, kajian berkenaan persamaan di kalangan wartawan dalam membuat pemilihan berita pula menunjukkan hasil yang tidak konsisten (Kim & Bae, 2006). Kajian teoritikal ini secara amnya membincangkan bagaimana sesuatu peristiwa boleh menjadi berita dengan merujuk kepada beberapa pandangan dan paradigma kewartawanan dengan menggunakan kaedah penaakulan induktif. Apa yang dilakukan sebagai usaha awal ini ialah menelusuri kekuatan dan kelemahan setiap paradigma ilmu kewartawanan di samping pandangan-pandangan yang berbeza akan model kewartawanan yang ideal. Ini penting untuk mengenalpasti kekurangan sedia ada dalam usaha membentuk model pemberitaan yang bersesuaian dengan masyarakat Malaysia. Rumusan kepada hasil analisis ini mendapati nilai-nilai murni yang cuba diketengahkan oleh mana-mana ajaran agama sebenarnya adalah sama iaitu menyeru kepada kebaikan dan mencegah kemungkaran dan nilai-nilai ini sudah sedia ada dalam nilai-nilai berita yang menjadi asas kriteria kepada pemilihan sesuatu peristiwa. Justeru itu, taksonomi nilai-nilai berita yang mula dieksplorasi oleh Galtung dan Ruge (1965) wajar dijadikan sebagai asas permulaan kepada pencarian model kewartawanan yang baharu.
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DURAN, Tansu, e Özgür ÖNAL. "The Relationship Between The Nutrition Map Of The Families in Isparta Center and The Obesity Status Assessment". SDÜ SAĞLIK BİLİMLERİ DERGİSİ, 13 de abril de 2023, 78–86. http://dx.doi.org/10.22312/sdusbed.1216551.
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Amaç: Market rafları baz alınarak tarafımızca hazırlanan, obeziteye neden olması beklenen besinlerden oluşturulan beslenme haritası eşliğinde haneler ziyaret edilmiştir. Hanede bulunan besin miktarları, hane halkının sosyodemografik özellikleri, yeme tutumları ve fiziksel aktivite (FA) düzeyleri ile obezite ilişkisini incelemek amaçlanmıştır. Gereç ve Yöntem: Kesitsel analitik tipte yapılan araştırma 2019-2021 bahar döneminde, çalışmaya katılmayı kabul eden hane halkına bizzat ulaşılarak yapılmıştır. Örnekleme yöntemi olarak olasılıksız örnekleme yöntemlerinden kota örnekleme yöntemi kullanılmıştır. Katılımcıların sosyo-demografik verileri (Kişisel Bilgi Formu), yeme tutumları (Yeme Tutum Testi), fiziksel aktivite değişkenleri (Uluslararası Fiziksel Aktivite Değerlendirme Anketi Kısa Formu) ve hanelerde bulunan obeziteye neden olması beklenen besinlerin gruplandırılmasıyla elde edilen beslenme haritaları ile obezite durum değerlendirilmeleri yapılmıştır. Bulgular: Katılımcıların boy ortalaması 170,8±8,4, ağırlık ortalaması 76,0±14,2, vücut kitle indeksi(VKİ) ortalaması 26,0±4,2 ve yaş ortalaması 41,6±11,9 (min-maks=23-81) olarak tespit edilmiştir. Araştırmaya göre 10 kişiden 1‟inin evinde 2,5 litre ve fazlası gazlı içecek, 2 kişiden 1‟inin evinde hazır meyve suyu bulunmaktadır. Şekerli besin grupları incelendiğinde ise reçel %94, beyaz şeker %90 bulunma oranı ile hanelerde en çok bulunan şekerli besinlerdir. Çikolata, reçel, tatlandırıcı, şekerleme, beyaz şeker, yapay çikolata, gıda şurupları, dondurma ve kurutulmuş meyve düzeylerinin VKİ‟ ye etkisi saptanmamıştır. %91,3 oranla beyaz un, yüksek karbonhidrat içerikli besin grubundan, hanelerde en çok bulunan besindir. Sonuç: Beslenme haritası ile obezite durum değerlendirilmesi yapıldığında kadınların erkeklere oranla obeziteye daha yatkın olduğu, artan gelir düzeyi ile obezite riskinin azaldığı, yaş ile beraber obezite riskinin arttığı ve sigara kullananların kullanmayanlara oranla daha düşük vücut kitle indeksine sahip olduğu bulunmuştur.
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Romanazzi, Tiziana, Daniele Zanella, Mary Hongying Cheng, Behrgen Smith, Angela M. Carter, Aurelio Galli, Ivet Bahar e Elena Bossi. "Bile Acids Gate Dopamine Transporter Mediated Currents". Frontiers in Chemistry 9 (10 de dezembro de 2021). http://dx.doi.org/10.3389/fchem.2021.753990.
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Bile acids (BAs) are molecules derived from cholesterol that are involved in dietary fat absorption. New evidence supports an additional role for BAs as regulators of brain function. Sterols such as cholesterol interact with monoamine transporters, including the dopamine (DA) transporter (DAT) which plays a key role in DA neurotransmission and reward. This study explores the interactions of the BA, obeticholic acid (OCA), with DAT and characterizes the regulation of DAT activity via both electrophysiology and molecular modeling. We expressed murine DAT (mDAT) in Xenopus laevis oocytes and confirmed its functionality. Next, we showed that OCA promotes a DAT-mediated inward current that is Na+-dependent and not regulated by intracellular calcium. The current induced by OCA was transient in nature, returning to baseline in the continued presence of the BA. OCA also transiently blocked the DAT-mediated Li+-leak current, a feature that parallels DA action and indicates direct binding to the transporter in the absence of Na+. Interestingly, OCA did not alter DA affinity nor the ability of DA to promote a DAT-mediated inward current, suggesting that the interaction of OCA with the transporter is non-competitive, regarding DA. Docking simulations performed for investigating the molecular mechanism of OCA action on DAT activity revealed two potential binding sites. First, in the absence of DA, OCA binds DAT through interactions with D421, a residue normally involved in coordinating the binding of the Na+ ion to the Na2 binding site (Borre et al., J. Biol. Chem., 2014, 289, 25764–25773; Cheng and Bahar, Structure, 2015, 23, 2171–2181). Furthermore, we uncover a separate binding site for OCA on DAT, of equal potential functional impact, that is coordinated by the DAT residues R445 and D436. Binding to that site may stabilize the inward-facing (IF) open state by preventing the re-formation of the IF-gating salt bridges, R60-D436 and R445-E428, that are required for DA transport. This study suggests that BAs may represent novel pharmacological tools to regulate DAT function, and possibly, associated behaviors.
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Pokhrel, Hari Prasad. "Editorial Vol.1". Siddhajyoti Interdisciplinary Journal 1 (30 de janeiro de 2020). http://dx.doi.org/10.3126/sij.v1i0.34920.
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Siddajyoti Education Campus (SJEC) is a community campus located at Kamalamai Municipality-5, Phosretar, a rural area of Sindhuli district. The campus is affiliated with Tribhuvan University, and managed by the local community envisioning to stand as one of the leading academic institutions in the country for quality education and promoting research activities. It follows the rules, regulations, guidelines, curriculum, examination system, and other academic norms of Tribhuvan University. The campus enrolls and provides support to the students of rural areas in this region particularly Chhori (daughters) and Buhari (daughters-in-law).
Since research is to create new knowledge and to use the existing bodies of knowledge in a new and creative ways so as to generate new concepts, methodologies and understandings, SJEC believes on developing research culture for effective, meaningful and productive classroom instruction in this ever-changing world. Apprehending this reality SJEC has established Research Management Cell (RMC) with the support of University Grants Commission (UGC). RMC has been launching research oriented trainings, workshops, seminars, course refresher trainings, capacity development trainings to develop professional skills of teachers as well as students. RMC also supports teachers for doing mini researches, and students for thesis writing.
SJEC believes that delivering lecture and providing the same old notes culture has been failure in our context. Therefore, RMC decided to publish research-based academic journal, Siddhajyoti Interdisciplinary Journal (SIJ), an official journal of SJEC. It aims to encourage teachers to read, write and share their researches and ideas among teachers, trainers, researchers, policy makers, and practitioners of interdisciplinary subjects (Education, Curriculum, Psychology, EPM, English, Nepali, Mathematics, Social, Population, Economics, Health and physical Education etc.) in the academic world through publication.
In this first volume of Siddhajyoti Interdisciplinary Journal (SIJ), we have included 15 articles by following rigorous peer review and editing process. This volume includes the articles of novice scholars of Nepal from English, Health, Economics, Nepali, Education and Mathematics backgrounds. In the article from Nepali discipline Dr. Jibalal Basyal explores the contemporary issues of writing Nepali poem, Surendra Bam, Heramba Raj Bastola, Ramesh Bhattrai, Krishna Prasad Subedi and Jhagindra Raj Dhakal analyse and synthesise the ideas of professional development of language teacher, role of teaching materials in multilingual class, self evaluation practice in instruction development, different aspects of origin of language and various types and ways of reading, respectively.
In English Nani Babu Ghimire explores the responsibilities and expectation of the teachers of community campus for their professional development, Man Bahadur Jora talks about the burning issue of English Medium Instruction regarding ethnics groups' parents believe on it, Dipak Tamang attempted to justify the language policy in Nepal concerning on multilingual practice in family, and Sakun Kumar Joshi discusses about linguistic intelligences at basic level learners in Nepal. Likewise, Keshar Bahadur Kunwar argues on foreign direct investment and economic growth of Nepal, Yam Prasad Pandeya looks into parental factors and their effects on students' learning in mathematics, Sapana Adhikari investigates struggle of Tamang children in achieving elementary education, Shanti Devi Rai explains Suptulung as indigenous knowledge of Kirat Rai people in Nepal. Exploring the issue of Health education Kosh Bilash Bagale avers about menstruation as still dark side of the society in 21th century in Nepal.
We are very confident that these articles will be instrumental in guiding the coming generations of multidisciplinary practitioners of Nepal. We make call to all valuable readers to contribute by writing for the upcoming issues, reading articles and writing comments as well as bringing changes in your profession. Let's try our hand not only in the classroom but also in strengthening our academic development through this publication.
We express our gratitude to all authors for their valuable contributions. Our sincere gratitude goes to all reviewers, who supported the Editorial Team throughout the process. We are equally grateful to Campus Management Committee of SJEC and RMC for their continuous support. We are also thankful to the designer, Prakhar Sindhuliya for the elegant design.
Happy reading!
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Ling Hoon Leh, Oliver, Muhammad Shamsul Azdhar Zulkapli, Kwong Qi Jie e Nurul Ashikin Mabahwi. "SATISFACTION OF RESIDENTS ON THE REDEVELOPMENT OF NATURAL DISASTER AREA. CASE STUDY: KUALA KRAI, KELANTAN, MALAYSIA". PLANNING MALAYSIA JOURNAL 16, n.º 7 (4 de novembro de 2018). http://dx.doi.org/10.21837/pmjournal.v16.i7.500.
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Referring to the Malaysian National Security Council, disaster is defined as a catastrophic situation that claimed many lives and caused extensive damage to property and potentially endangers the public peace and security. In Malaysia, there were few natural disaster events that can be said to be among the worst ever in terms of the number of deaths and damages. However, these occurrences were not as severe as overseas. At the end of December 2014, there was a catastrophic flood called as the 'Bah Kuning' was hitting the east coast of Peninsular Malaysia. It resulted in almost 85% of the total Kuala Krai area inundated by flood water. One of the elements in post-disaster recovery is rebuilding shelter for victims. Regardless, it is important to research on residents’ satisfaction as it will affect the well-being directly or indirectly. Thus, a study was carried out to evaluate the satisfaction of residents (victims) on the “New Permanent Houses” (Rumah Kekal Baharu, RKB) that they received from the redevelopment project. A questionnaire survey was carried out to collect and understand respondents’ satisfaction on the redevelopment of their housing area, in specific, the quality of their newly reconstructed houses and the supporting facilities or infrastructure in their area. From the analysis, it was found that majority of the respondents were satisfied with their newly redeveloped houses and the infrastructure. The satisfaction level was associated with the locational and land ownership factors.
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Robb, Thomas. "From the Editor". Teaching English as a Second or Foreign Language--TESL-EJ 28, n.º 1 (1 de maio de 2024). http://dx.doi.org/10.55593/ej.28109fromed.
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[First part only] Dear Readers, Welcome to the first issue of our 28th Volume! This issue contains a “Special Issue” within it on “Between Indisposition and Perseverance: Disrupted Language Teacher Identities in Times of Uncertainty” ably edited by Hyunjin Jinna Kim and Huseyin Uysal. We hope that you will find it both informative and relevant to your own teaching context. In addition, this issue contains 8 feature articles. We offer our usual smörgåsbord for your reading pleasure, topics include learner autonomy, ChatGPT, sustainable development goals in global education, digital literacy, vocabulary knowledge for writing, speech pragmatics of hotel negotiations, migrant learners, and language learner beliefs. In order to make our articles useful to our global readership, we are strictly enforcing our policy that articles must be applicable to other contexts despite the research having been carried out in a single country. SCOPUS ranking improves. TESL-EJ’s ranking on the newly released 2024 version of scimagojr.com‘s SCOPUS listing has moved up to #253 from #267 out of the 312 journals in their Q1 “Linguistics and Language” category. We congratulate our editorial team, our contributors and you, the readers, for the steady improvement in our listing over the five years that we have been listed. Kudos. We are proud to say that past Review Editor, Ilka Kostka and our new Review Editor, Rachel Toncelli (see below) received the TESOL “Ron Chang Lee Award for Excellence in Classroom Technology,” while Huseyin Uysal, co-editor of the current Special Issue, received the “TESOL Leadership Mentoring Program Award” for 2024. Congratulations to all! Passages. Rachel Toncelli (Northeastern University) joins Dylan Burton on our Book Review Team. Dr. Toncelli was introduced by our former review editor and colleague, Ilka Kotska who co-authored the “On the Internet” article on ChatGPT in our November 2023 issue. We thank Behzad Mansouri for his long service to TESL-EJ as a co-editor, media review editor, special issue editor and special mentor to struggling authors. Behzad has now moved away from ELT, and is currently involved in a study of “community-engagement and leadership.” New book! We are pleased to announce another book publication, Tips for Writing Well: Research-Based Principles, by Scott Alkire. This volume contains 25 easy-to-read and easy-to-follow tips on effective academic writing. The topics range from how to find sources to improving your style to grammar and proofreading. It is free for download in PDF from this site. It will soon be available on Amazon in ebook and paperback formats. Our policy is that 100% of profits from this and all of our books go to supporting TESL-EJ’s mission to remain free from advertising, and free from subscription fees. Thank you for considering a purchase. Thanks to recent reviewers. We thank the reviewers of all submissions that had reached a decision since our last issue – regardless of whether the paper was accepted or declined. Thanks go to: Abdul Syahid, Adrian Leis, Ahmed Bashir, Andrias Susanto, Anh Ton-Nu, Aránzazu García-Pinar, Aurelio Vilbar, Azran Azmee Kafia, Baburam Upadhaya, Bao Trang Thi Nguyen, Betsy Gilliland, Boudjemaa Dendenne , Burak Senel, C-S Anna Chang, Chin Ee Loh, Cihat Atar, Claire Louise Rodway, Colin William Campbell, Dale Brown, Danial Babajani Azizi, Daron Benjamin Loo, David Berry, Eli Hinkel, Elisabet Murtisari, Emrah Cinkara, Eric Hagley, Fatemeh Ranjbaran, Flora Debora Floris, Frank Hermann, Gözde Balıkçı, Gina Paschalidou, Grant Eckstein, Ha Hoang, Hamid Bahador, Hjalmar Hernandez, I Putu Indra Kusuma, Ilka Kostka, Ismail Xodabande, Jofen Wu Han, Juland Salayo, Kathleen Eilers-crandall, Kuang Li, Kyle R. Van Horn, Larry Xethakis, Leonardo Veliz, Made Hery Santosa, Md. Didar Hossain, Meliha R Simsek, Michael Joseph Ennis, Minh Le, Mirjam Anugerahwati, Napak-on Sritrakarn, Nurkamilah, Omer Gokhan ULUM, Paul Mathieson, Penkhae Wongosuriya, Peter Ilic, Piyapong Laosrirattanachai, Rita Elaine Silver, Sachiko Nakamura, Shaun Manning, Shizuka Sakurai, Sophia Skoufaki, Theresa A Antes, Ufuk Atas, Valentin Werner, Vijayakumar Chintalapalli, Xiaoli YU, Xirui Cai, Yosefina Rosdiana Su and Zainurrahman. Another Special Issue production by Thomas Farrell is in the offing! Moving Forward With Reflective Practice in TESOL is now calling for contributions, to be published in the August 2025 issue. Best wishes, Thomas Robb, for the Editorial Team